Tranexamic acid glutathione complex aqueous solution and preparation method thereof

CN116637040BActive Publication Date: 2026-07-03CHENGDU JOY YOUNG BIOTECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
CHENGDU JOY YOUNG BIOTECH CO LTD
Filing Date
2021-08-16
Publication Date
2026-07-03

AI Technical Summary

Technical Problem

Existing tranexamic acid and glutathione compound formulations are prone to forming particles and precipitating in water. Furthermore, glutathione has strong antioxidant properties, making it difficult to produce stable, high-concentration skincare products. Existing methods are either costly or have complex processes.

Method used

A stable tranexamic acid-glutathione composite aqueous solution was prepared by using an aqueous solution of tranexamic acid, glutathione, cyclodextrin and ascorbic acid in a specific ratio, and by adjusting the specific order of addition and pH.

Benefits of technology

The prepared composite aqueous solution has moderate viscosity, is uniform and stable, and does not change color or precipitate particles when stored at room temperature for a long time. Its antioxidant properties remain stable, making it suitable for whitening and spot-removing cosmetics. It is low in cost and has a simple process.

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Abstract

This invention relates to a tranexamic acid-glutathione complex aqueous solution and its preparation method, belonging to the field of cosmetic technology. The technical problem solved by this invention is to provide a low-cost tranexamic acid-glutathione complex aqueous solution. This complex aqueous solution comprises the following components in parts by weight: 2-6 parts tranexamic acid, 12-20 parts glutathione, 10-20 parts cyclodextrin, and 3-8 parts ascorbic acid. This invention successfully prepares the tranexamic acid-glutathione complex aqueous solution using a specific order and method of adding the ingredients. This complex aqueous solution has moderate viscosity, is uniform and stable, and does not separate into layers or precipitate particles after being left at room temperature for 6 months. It can be used daily as a whitening and spot-removing cosmetic with good effects. Furthermore, the preparation method is simple, low-cost, and suitable for industrial production.
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