Thrombectomy device

Abstract

The embodiment of the present application provides a kind of to take out device, comprising: first pipe and multiple main take out support;Multiple main take out support is sequentially arranged in the first pipe along the axial direction of the first pipe;And along the axial direction of the first pipe, the radial dimension of multiple main take out support is sequentially increased.The above technical scheme is used, can be sequentially taken out by multiple main take out support and the embolus of different radial dimension in blood vessel is handled, reduces the number of times that the embolus is taken out in the channel of blood vessel, to reduce the operation complexity of the embolus process.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a thrombectomy device. Background Technology

[0002] Currently, the main treatments for deep vein thrombosis (DVT) include anticoagulation therapy, local thrombolysis, and mechanical thrombectomy. However, some patients have contraindications to anticoagulation or thrombolysis, making mechanical thrombectomy the primary option. Mechanical thrombectomy mainly includes aspiration thrombectomy and stent thrombectomy. Among these, stent thrombectomy is widely used in DVT treatment due to its advantages such as less blood loss and complications, shorter operation time, less trauma, and lower cost.

[0003] Specifically, the working principle of stent thrombectomy includes: using microcatheter technology, a microcatheter is delivered along the blood vessel channel to the embolism site, and then the thrombectomy stent is withdrawn from the microcatheter. At this point, the thrombectomy stent can self-expand radially along the blood vessel channel and come into contact with the embolus. During the withdrawal of the thrombectomy stent from the microcatheter, the stent can capture the embolus, thereby removing the embolus from the blood vessel channel and restoring blood flow to the blood vessel.

[0004] For patients with a high thrombus burden, excessive emboli captured by the stent can make stent withdrawal difficult. Current techniques address this by increasing the number of thrombectomy attempts to reduce the amount of emboli captured per attempt. However, this increases the complexity of the thrombectomy process. Therefore, developing an improved technique to reduce this complexity is a pressing technical challenge. Summary of the Invention

[0005] In view of this, embodiments of the present invention provide a thrombectomy device that can reduce the number of insertions and reduce the operational complexity of the thrombectomy process.

[0006] First, this embodiment of the invention provides a thrombectomy device, including: a first tube and multiple main thrombectomy supports;

[0007] The plurality of main thrombectomy brackets are sequentially arranged on the first tube along the axial direction of the first tube;

[0008] Furthermore, along the axial direction of the first tube, the radial dimensions of the plurality of main tapping supports increase sequentially.

[0009] Optionally, the main thrombectomy bracket includes: a first part, a second part, and a third part;

[0010] The first part is adapted to radially divide the embolus along the main embolic retrieval stent;

[0011] The second part is adapted to expand radially along the main thrombectomy bracket;

[0012] The first and / or the second part are also adapted to circumferentially divide the embolus along the main embolic stent;

[0013] The third part is adapted to collect the embolus after being cut by the first part and / or the second part.

[0014] Optionally, the first part is fixedly connected to the first tube;

[0015] The second part is fixedly connected to the first part and the third part, respectively.

[0016] Optionally, the first part includes:

[0017] A fastener adapted to be fixedly connected to the first tube.

[0018] Optionally, the second part and the third part are integrally formed.

[0019] Optionally, the second part and the third part are detachably and fixedly connected.

[0020] Optionally, the third part includes:

[0021] A sliding element, the sliding element being adapted to slide and engage with the first tube.

[0022] Optionally, the first tube includes:

[0023] A limiting portion is provided, which is adapted to limit the distance by which the sliding member slides along the axial direction of the first tube.

[0024] Optionally, the projection density of the first part on the cross-section of the main retrieval bracket is less than the projection density of the third part on the cross-section of the main retrieval bracket.

[0025] Optionally, the thrombectomy device further includes:

[0026] The second tube is coaxially disposed outside the first tube, and the relative position of the second tube and the first tube is adjustable. The second tube is adapted to accommodate the main thrombec support.

[0027] Optionally, the thrombectomy device further includes:

[0028] The third tube is coaxially disposed inside the first tube, and the relative position of the third tube and the first tube is adjustable;

[0029] A secondary thrombectomy bracket, the secondary thrombectomy bracket being adapted to be coupled to the first tube; and / or, the secondary thrombectomy bracket being adapted to be coupled to the third tube.

[0030] Optionally, there may be multiple secondary thrombectomy brackets, which are sequentially arranged in the third tube along its axial direction.

[0031] Optionally, the radial dimensions of the plurality of secondary thrombectomy brackets include at least two different radial dimensions;

[0032] The radial dimension variation of the plurality of auxiliary thrombectomy supports along the axial direction of the third tube is consistent with the radial dimension variation of the plurality of main thrombectomy supports along the axial direction of the first tube.

[0033] Optionally, the radial dimensions of the plurality of secondary thrombectomy brackets are the same.

[0034] Using the above technical solution, the multiple main thrombectomy stents can be sequentially arranged along the axial direction of the first tube, with the radial dimensions of the multiple main thrombectomy stents increasing sequentially. The main thrombectomy stent with the smaller radial dimension enters the vascular channel first to treat a portion of the embolus within its corresponding inner diameter range. Then, the main thrombectomy stent with the larger radial dimension enters the vascular channel later to treat the remaining embolus. Therefore, the thrombectomy device with the above structure, by sequentially treating embolus at different radial dimensions within the blood vessel using multiple main thrombectomy stents, can reduce the number of times the thrombectomy device needs to enter the vascular channel, thereby reducing the operational complexity of the thrombectomy process. Attached Figure Description

[0035] To more clearly illustrate the technical solutions of the embodiments of this specification, the drawings used in the description of the embodiments of this specification or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this specification. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0036] Figure 1 A schematic diagram of a thrombectomy system in the prior art is shown;

[0037] Figure 2 A schematic diagram of a thrombectomy device according to an embodiment of the present invention is shown;

[0038] Figure 3A A schematic diagram of a main thrombectomy support structure is shown in an embodiment of the present invention;

[0039] Figure 3B A schematic diagram of another main thrombectomy support structure is shown in an embodiment of the present invention;

[0040] Figures 4A to 4C This invention illustrates a schematic diagram of the structure of the second part of various main thrombectomy stents in embodiments of the present invention;

[0041] Figure 5 A schematic diagram of another thrombectomy device in an embodiment of the present invention is shown;

[0042] Figure 6 A cross-sectional schematic diagram of a vascular channel according to an embodiment of the present invention is shown. Detailed Implementation

[0043] As described in the background section, stent thrombectomy is widely used in the treatment of deep vein thrombosis (DVT). (See also...) Figure 1 The diagram illustrates a prior art thrombectomy system. The system includes a delivery device M and a thrombectomy stent N. The delivery device M includes an outer delivery tube M1 and a stent fixation tube M2. The outer delivery tube M1 is coaxially disposed outside the stent fixation tube M2, and the relative positions of the outer delivery tube M1 and the stent fixation tube M2 are adjustable. The thrombectomy stent N is fixed to the distal end of the stent fixation tube M2, and the distal end of the stent fixation tube M2 is provided with a guide cap M3. The thrombectomy stent N is a cavity structure made of a cylindrical braided mesh frame with shape memory effect. The thrombectomy stent N, with its opening facing proximally, can make close contact with the inner wall of the blood vessel channel. The thrombectomy stent N scrapes off the embolus and collects it within its cavity, returning to the outer delivery tube M1 along with the stent fixation tube M2.

[0044] For patients with a large thrombus burden, if too much embolus is embedded in the thrombectomy stent, it can cause difficulties in withdrawing the stent delivery catheter. To solve this problem, existing technologies reduce the amount of embolus captured by the stent in a single thrombectomy and increase the number of times the stent enters the vascular channel for thrombectomy. This method increases the operational complexity of the thrombectomy process. Therefore, how to provide an improved thrombectomy stent to reduce the operational complexity of the thrombectomy process has become an urgent technical problem to be solved.

[0045] To address the aforementioned issues, this invention provides a thrombectomy device comprising multiple main thrombectomy stents, each having at least two different radial dimensions. By sequentially using multiple main thrombectomy stents to remove emboli at different radial dimensions within the blood vessel, the number of times the thrombectomy device needs to enter the blood vessel channel for thrombectomy can be reduced, thereby reducing the operational complexity of the thrombectomy process.

[0046] To enable those skilled in the art to better understand and implement the embodiments of the present invention, the following describes the concept, scheme, principle, and advantages of the embodiments of the present invention in detail with reference to the accompanying drawings and through specific application examples.

[0047] In some embodiments of the present invention, the thrombectomy device may include: a first tube and a plurality of main thrombectomy supports;

[0048] The plurality of main thrombectomy brackets are sequentially arranged on the first tube along the axial direction of the first tube;

[0049] Furthermore, along the axial direction of the first tube, the radial dimensions of the plurality of main tapping supports increase sequentially.

[0050] Specifically, along the axial direction of the first tube, the radial dimensions of the plurality of main thrombectomy supports increase sequentially, and the radial dimensions of the plurality of main thrombectomy supports may include at least two different radial dimensions. The radial dimension corresponding to a main thrombectomy support may include the dimension of the fully expanded main thrombectomy support projected onto the cross-section of the thrombectomy device, the cross-section of the thrombectomy device being perpendicular to the axial direction of the first tube.

[0051] In practical applications, the distribution of multiple master thrombectomy stents in the thrombectomy device includes: the master thrombectomy stent with the smallest radial dimension is closest to the embolus, moving away from the embolus along the axis of the first tube, with the radial dimensions of the remaining master thrombectomy stents increasing sequentially. When multiple master thrombectomy stents are dragged toward the embolus, the master thrombectomy stent with the smaller radial dimension contacts the embolus earlier, and the master thrombectomy stent with the larger radial dimension contacts the embolus later. During the dragging of multiple master thrombectomy stents, the master thrombectomy stent with the smallest radial dimension can handle part of the embolus within the inner diameter range corresponding to its radial dimension in the vascular channel. Subsequent master thrombectomy stents can handle the part of the embolus within the inner diameter range corresponding to its radial dimension that has not been handled by the previous master thrombectomy stent. By sequentially treating emboli at different radial dimensions in the blood vessel with multiple master thrombectomy stents, the number of times the thrombectomy device needs to enter the blood vessel channel for thrombectomy can be reduced, thereby reducing the operational complexity of the thrombectomy process.

[0052] As an optional implementation, refer to Figure 2 , Figure 2 A schematic diagram of a thrombectomy device according to an embodiment of the present invention is shown. The thrombectomy device Q may include: a first tube G1 and two main thrombectomy supports 1 and 2; the main thrombectomy supports 1 and 2 are disposed on the first tube G1 and are distributed sequentially along the axial direction of the first tube G1; wherein, along the axial direction of the first tube G1, the radial dimension of the main thrombectomy support 1 is smaller than the radial dimension of the main thrombectomy support 2.

[0053] It is understood that the radial dimensions of the plurality of main retrieval supports distributed along the axial direction of the first pipe can be different from each other, or at least two main retrieval supports can have the same radial dimension, as long as it is ensured that at least two of the radial dimensions of the plurality of main retrieval supports distributed along the axial direction of the first pipe are different. Furthermore, this embodiment of the invention does not limit whether the main retrieval supports are axisymmetric structures; they can also be asymmetrical structures, and the shapes of the plurality of main retrieval supports distributed along the first pipe can be the same or different. In addition, Figure 2 Only two main retrieval supports are shown in the diagram. In actual implementation, the number of main retrieval supports can be flexibly set according to the actual application requirements.

[0054] As an optional implementation, continue to refer to Figure 2 The thrombectomy device Q may further include a second tube G2, which is coaxially disposed outside the first tube G1. The relative position of the second tube G2 and the first tube G1 is adjustable, and the second tube G2 is adapted to accommodate the main thrombectomy support.

[0055] By adjusting the relative positions of the second tube and the first tube, the main thrombectomy stent, which is in a compressed state before being released in the second tube, can be pushed into the vascular channel for subsequent thrombectomy. Similarly, by adjusting the relative positions of the second tube and the first tube, the main thrombectomy stent, which has expanded into a preset shape in the vascular channel, can be pulled back into the first tube, thereby removing the embolus captured by the main thrombectomy stent from the vascular channel.

[0056] In a specific implementation, the main thrombectomy stent may include a first part, a second part, and a third part. The first part is adapted to radially divide the embolus along the main thrombectomy stent; the second part is adapted to radially expand along the main thrombectomy stent; the first part and / or the second part is also adapted to circumferentially divide the embolus along the main thrombectomy stent; and the third part is adapted to collect the embolus divided by the first part and / or the second part.

[0057] Specifically, the first part may include a component distributed radially along the main thrombectomy stent, and this radially distributed component can segment the embolus along the radial direction of the vascular channel; the first part and / or the second part may include a component distributed circumferentially along the main thrombectomy stent, and this circumferential component can segment the embolus along the circumference of the vascular channel. The segmented portion of the embolus detaches from the vascular channel and can be captured and collected by the third part.

[0058] As an optional example, in conjunction with the reference Figure 2 and Figure 3A , Figure 3AA schematic diagram of a main thrombectomy support structure according to an embodiment of the present invention is shown. The main thrombectomy support may include a first part 11, a second part 12, and a third part 13. The first part 11 may include a plurality of cutting members 111 and a plurality of peeling members 112, wherein the two ends of the cutting members 111 are at different distances from the axis of the main thrombectomy support 1, so that the first part 11 has a component distributed radially along the main thrombectomy support 1. The combined projection of the plurality of peeling members 112 on the cross-section of the main thrombectomy support 1 is circular, so that the first part 11 has a component distributed circumferentially along the main thrombectomy support 1. The second part 12 may include a plurality of annular members 121, wherein the annular members 121 are adapted to expand radially along the main thrombectomy support 1, so that the second part 12 has a component distributed circumferentially along the main thrombectomy support 1. Dragging the main thrombectomy stent 1, the cutting member 111 can divide the embolus along the radial direction of the blood vessel channel, and the peeling member 112 and the annular member 121 can both divide the embolus along the circumferential direction of the blood vessel channel.

[0059] As another alternative example, the difference from the previous example is that the first part may not include multiple stripping members, and the cutting member of the first part is directly connected to the second part. That is, by dragging the main thrombectomy stent, the cutting member can divide the embolus radially along the vascular channel, and the annular member can divide the embolus circumferentially along the vascular channel.

[0060] In practice, the first part is fixedly connected to the first tube.

[0061] As an optional implementation, continue to combine with reference Figure 2 , Figure 3A and Figure 3B The first part 11 may further include a fixing member 113, the ends of a plurality of cutting members 111 being connected to the fixing member 113, and the fixing member 113 being fixedly connected to the first tube G1, so that the cutting members 111 can be fixedly connected to the first tube G1 through the fixing member 113. Specifically, the fixing member 113 may be an annular structure sleeved and welded to the first tube G1.

[0062] In practice, the specific structure of the second part can be determined according to the specific circumstances.

[0063] As an optional example, in conjunction with the reference Figure 3B and Figure 4A , Figure 4A It shows Figure 3BThe schematic diagram of the second part of the main thrombec support shown indicates that the second part 12 may include multiple annular members 121 and multiple connecting members 122. The multiple annular members 121 are coaxially arranged, and the connecting members 122 are parallel to the axial direction of the annular members. The annular members 121 may include multiple support members 2211. The multiple support members 2211 are connected end to end to form an annular structure. Each pair of support members 1211 are arranged in a V-shape to form a V-shaped angle. Each V-shaped angle is fixedly connected to a connecting member 122.

[0064] When the main thrombectomy stent is in a compressed state, the angle of the V-shape is at its minimum, and the interaction force between the two adjacent supports is at its maximum. When the main thrombectomy stent is released in the vascular channel, the annular member expands under the interaction between the two adjacent supports, the angle of the V-shape gradually increases, and the interaction force between the two adjacent supports gradually decreases until the main thrombectomy stent returns to the preset shape or the main thrombectomy stent comes into contact with the inner wall of the vascular channel.

[0065] As another optional example, see Figure 4B , Figure 4B A schematic diagram of the structure of the second part of another main thrombectomy bracket in an embodiment of the present invention is shown. The second part 12 may include a mesh structure formed by the intersection of multiple connectors 121.

[0066] As another optional example, see Figure 4C , Figure 4C This diagram illustrates the structure of the second part of another type of main thrombectomy bracket according to an embodiment of the present invention. The second part 12 can also be along... Figure 4A The axially distributed partial structure of the second part 12, and along Figure 4B The axially distributed partial structures of the second part 12 together form a hybrid structure.

[0067] In practice, the first part can be fixedly connected to the second part. For example, the first part can be detachably or non-detachably fixedly connected to the second part.

[0068] As an optional implementation, refer to Figure 3A The peeling part 112 of the first part 11 and the connecting part 122 of the second part 12 are integrally formed.

[0069] In practice, the second part can be fixedly connected to the third part. For example, the second part can be detachably or non-detachably fixedly connected to the third part.

[0070] As an optional example, see [reference] Figure 3AThe third part 13 is integrally formed with the endpoint of the V-shaped angle between the end of the second part 12 and the connector 122.

[0071] As another optional example, in conjunction with reference Figure 3B and Figure 4A The connector 122 at the end of the second part 12 near the end of the third part 13 is provided with a connecting ring 123. The third part 13 is fixedly wound around the connecting ring 123 and the V-shaped angle of the end of the second part 12 near the end of the third part 13.

[0072] In specific implementations, one or more of the first part, the second part, or the third part can be made by laser cutting a shape memory material. As an optional example, the shape memory material may include nickel-iron alloys, spring steel, shape memory polymers, etc., which are materials that can expand into a preset shape when subjected to pressure or temperature changes.

[0073] In a specific implementation, the projection density of the first part on the cross-section of the main retrieval bracket is less than the projection density of the third part on the cross-section of the main retrieval bracket.

[0074] By setting the projection density of the first part on the cross-section of the main thrombectomy stent to be less than the projection density of the third part on the cross-section of the main thrombectomy stent, the area of ​​the cross-section of the segmented embolus can be larger than the area of ​​the cross-section through which the third part is allowed to pass. Dragging the main thrombectomy stent along the vascular channel, the embolus segmented by the first part can remain within the main thrombectomy stent and be removed from the vascular channel by the main thrombectomy stent.

[0075] As an optional example, see [reference] Figure 3A The first part 11 may include three cutting elements 111 extending radially along the main thrombec support and evenly distributed circumferentially along the main thrombec support. The projection of the three cutting elements 111 onto the cross-section of the main thrombec support divides the cross-section of the main thrombec support into three equal parts. The third part 13 may include twelve filter elements 131 evenly distributed circumferentially along the main thrombec support. The projection of the twelve filter elements 131 onto the cross-section of the main thrombec support divides the cross-section of the main thrombec support into twelve equal parts.

[0076] In practical applications, the main thrombectomy stent is dragged along the vascular channel. The embolus corresponding to the radial dimension of the main thrombectomy stent is divided into three equal parts by three cutting elements. The cross-section of each part of the embolus is approximately one-third the cross-section of the main thrombectomy stent. The cross-sectional area of ​​the embolus allowed to pass through the third part should be less than one-twelfth the cross-sectional area of ​​the main thrombectomy stent. Therefore, the embolus cut by the cutting elements will remain in the main thrombectomy stent and be removed from the vascular channel by the main thrombectomy stent.

[0077] As another alternative example, combined Figure 3B and Figure 4A As shown, the difference from the previous alternative example is that the third part 13 can be a conical mesh structure woven from twelve filter elements 131. The projection of the conical mesh structure on the cross-section of the main thrombec support divides the cross-section into multiple grid regions. Along the direction of the third part 13 away from the second part 12, the area of ​​each grid region gradually decreases, and each grid region is less than one-third of the cross-section of the main thrombec support.

[0078] In practical applications, the main thrombectomy stent is dragged along the vascular channel. The embolus corresponding to the radial dimension of the main thrombectomy stent is divided into three equal parts by three cutting elements. The cross-sectional area of ​​each part of the embolus is approximately one-third the cross-sectional area of ​​the main thrombectomy stent. The cross-sectional area of ​​the embolus allowed to pass through in the third part is less than one-third the cross-sectional area of ​​the main thrombectomy stent. Therefore, the embolus cut by the cutting elements will remain in the main thrombectomy stent and be removed from the vascular channel by the main thrombectomy stent.

[0079] In a specific implementation, the third part can slide and engage with the first tube. The main thrombectomy bracket can include two states: compression and expansion. When the main thrombectomy bracket changes from the compression state to the expansion state, the axial component of one or more of the first, second, or third parts will change, causing a change in the axial length of the main thrombectomy bracket. Since the first part is fixedly installed with the first tube, by setting the third part to slide and engage with the first tube, the change in axial length caused by the change in the state of the main thrombectomy bracket can be absorbed, thereby facilitating the switching of the main thrombectomy bracket between the two states.

[0080] As an optional example, see [reference] Figure 3A The third part 13 may include a slider 132, which is integrally formed with the ends of the plurality of filter elements 131, and the slider 132 can slide and engage with the first tube. Specifically, the slider may be an annular structure sleeved on the first tube.

[0081] As another optional example, see Figure 3B The third part 13 may include a sliding member 132, and the filter element 131 has a rope-like structure. Multiple filter elements 131 are wound and fixedly arranged with the sliding member 132, and the sliding member 132 can slide and cooperate with the first tube. Specifically, the sliding member can be a ring-shaped structure sleeved on the first tube.

[0082] As an optional implementation, refer to Figure 2 The first tube G1 may include a limiting part X, which is adapted to limit the distance the sliding member slides along the axial direction of the first tube G1. The third part 13 is made of a memory material and has a certain elasticity. As the main thrombectomy bracket 1 moves, the thrombus inside the main thrombectomy bracket 1 gradually increases, which will continuously squeeze the third part 13, causing the third part 13 to deform along the axial direction of the first tube G1. By providing the limiting part X on the first tube G1 on the side of the third part 13 away from the first part 11, the deformation of the third part 13 along the axial direction of the first tube G1 can be effectively controlled, thereby avoiding excessive deformation of the third part 13.

[0083] As an optional implementation, refer to Figure 2 The thrombectomy device Q may include a third tube G3, wherein the third tube G3 is coaxially disposed inside the first tube G1, and the relative position of the third tube G3 and the first tube G1 is adjustable.

[0084] As an optional example, continue to refer to Figure 2 The end of the third tube G3 is provided with a broken plug element S, which can pass through the plug to form a channel for the thrombus removal device to pass through.

[0085] During thrombectomy, embolic fragments may pass through the gap in the third part and remain in the vascular channel. These fragments are in a free state and can move with the blood in the vascular channel, which can easily lead to problems such as pulmonary embolism.

[0086] To address this technical problem, in a specific implementation, the thrombectomy device Q may include a secondary thrombectomy support, which is located on the side of the main thrombectomy support away from the second tube. The secondary thrombectomy support can perform secondary capture of embolic debris.

[0087] In a specific implementation, the projection density of the auxiliary thrombectomy bracket on the cross-section of the main thrombectomy bracket is set to be greater than the projection density of the third part of the main thrombectomy bracket on the cross-section of the main thrombectomy bracket.

[0088] As an optional example, the secondary thrombectomy stent may include a disc-shaped mesh structure woven from memory material, wherein the projection density of the secondary thrombectomy stent on the cross-section of the vascular channel is set to be greater than the projection density of the third part of the primary thrombectomy stent on the cross-section of the vascular channel.

[0089] As another alternative example, the secondary thrombectomy stent may include a balloon structure.

[0090] In specific implementations, the secondary thrombectomy bracket is adapted to be coupled to the first tube; and / or, the secondary thrombectomy bracket is adapted to be coupled to the third tube. The coupling may include a direct connection or an indirect connection.

[0091] As an optional example, one end of the secondary thrombectomy bracket can be connected to the sliding member of the primary thrombectomy bracket, and the other end can be connected to the thrombectomy member at the end of the third tube. The first part of the primary thrombectomy bracket is welded and fixed to the first tube, and the secondary thrombectomy bracket is indirectly connected to the first tube through the connection with the sliding member of the primary thrombectomy bracket. The secondary thrombectomy bracket is made of shape memory material. By adjusting the relative position of the third tube and the first tube, when the length of the secondary thrombectomy bracket along the axial direction of the first tube increases, the radial dimension of the secondary thrombectomy bracket can be decreased; when the length of the secondary thrombectomy bracket along the axial direction of the first tube decreases, the radial dimension of the secondary thrombectomy bracket can be increased.

[0092] As another alternative example, the secondary thrombectomy stent can be welded to the third tube. The secondary thrombectomy stent is made of an elastic material (e.g., medical rubber), and its radial dimensions can be adjusted by filling it with saline solution.

[0093] As another alternative example, the secondary thrombectomy bracket can be connected to the sliding member of the primary thrombectomy bracket. The first part of the primary thrombectomy bracket is welded and fixed to the first tube, and the secondary thrombectomy bracket is indirectly connected to the first tube through the connection with the sliding member of the primary thrombectomy bracket.

[0094] In a specific implementation, there may be multiple secondary thrombectomy supports, which are sequentially arranged in the third tube along the axial direction of the third tube.

[0095] In practice, the radial dimensions of multiple secondary thrombectomy supports can be determined according to the specific circumstances.

[0096] As an optional example, the radial dimensions of the plurality of auxiliary thrombectomy supports include at least two different radial dimensions; the radial dimension variation of the plurality of auxiliary thrombectomy supports along the axial direction of the third tube is consistent with the radial dimension variation of the plurality of main thrombectomy supports along the axial direction of the first tube.

[0097] As a specific example, refer to Figure 2 The thrombectomy device Q may include two main thrombectomy supports 1 and 2, and two auxiliary thrombectomy supports 3 and 4. The radial dimension of the main thrombectomy support 1 is smaller than that of the main thrombectomy support 2, and the radial dimension of the auxiliary thrombectomy support 3 is smaller than that of the auxiliary thrombectomy support 4. The main thrombectomy support 1, the main thrombectomy support 2, the auxiliary thrombectomy support 3, and the auxiliary thrombectomy support 4 are arranged in sequence along the direction away from the second tube.

[0098] As another optional example, see Figure 5 , Figure 5 This diagram illustrates the structure of another thrombectomy device according to an embodiment of the present invention. Figure 2 The difference in the thrombectomy device shown is that the thrombectomy device may include three auxiliary thrombectomy brackets 3, 4, and 5 with the same radial dimension.

[0099] To enable those skilled in the art to better understand and implement the thrombectomy device in the embodiments of the present invention, a specific example in conjunction with a specific scenario is described below.

[0100] As a specific example, in conjunction with reference Figure 2 , Figure 3A , Figure 3B and Figure 6 ,in, Figure 6 A cross-sectional schematic diagram of a vascular access channel according to an embodiment of the present invention is shown. The thrombectomy device Q includes: main thrombectomy stents 1 and 2, auxiliary thrombectomy stents 3 and 4, a first tube G1, a second tube G2, and a third tube G3. The radial dimension of the second part 12 of the main thrombectomy stent 1 in a preset shape is half the radial dimension of the second part 22 of the main thrombectomy stent 2 in a preset shape. The maximum radial dimension of the auxiliary thrombectomy stent 3 is the same as the radial dimension of the second part 12 of the main thrombectomy stent 1 in a preset shape. The maximum radial dimension of the auxiliary thrombectomy stent 4 is the same as the radial dimension of the second part 22 of the main thrombectomy stent 2 in a preset shape. The main thrombectomy stents 1, 2, 3, and 4 are arranged sequentially, with the interception capability of the third part 13, third part 23, 3, and 4 increasing sequentially.

[0101] When the main thrombectomy stents 1 and 2 and the auxiliary thrombectomy stents 3 and 4 are placed in the vascular channel T, the main thrombectomy stent 2 and the auxiliary thrombectomy stent 4 are in close contact with the inner wall of the vascular channel T, the radial dimension of the second part 12 corresponds to region S1, and the difference between the radial dimensions of the second part 22 and the second part 12 corresponds to region S2.

[0102] During the dragging of the main thrombectomy stents 1 and 2 and the auxiliary thrombectomy stents 3 and 4, the first part 11 of the main thrombectomy stent 1 first cuts the embolus in region S1 into free embolus and collects it into the second part 12 of the main thrombectomy stent 1. The third part 13 intercepts the embolus that has entered the second part 12 of the main thrombectomy stent 1 within the main thrombectomy stent 1 to prevent embolus escape. Subsequently, the main thrombectomy stent 2 moves close to the inner wall of the vascular channel T. The first part 11 of the main thrombectomy stent 2 further cuts the embolus in region S2 (including embolus adhering to the inner wall of the vascular channel) into free embolus and collects it into the second part 12 of the main thrombectomy stent 2. The third part 13 of the main thrombectomy stent 2 intercepts the embolus that has entered the second part 12 of the main thrombectomy stent 1 within the main thrombectomy stent 1 to prevent embolus escape. The embolus in the second part 12 of the thrombectomy stent 2 is intercepted within the main thrombectomy stent 2 to prevent escape. Since the interception performance of the third part 13 of the main thrombectomy stent 2 is better than that of the third part 13 of the main thrombectomy stent 1, the third part 13 of the main thrombectomy stent 2 can also intercept some embolus fragments that escape from the third part 13 of the main thrombectomy stent 1. Subsequently, the auxiliary thrombectomy stents 3 and 4 continue to capture the embolus fragments that escape from the main thrombectomy stents 1 and 2. At the same time, since the auxiliary thrombectomy stent 4 is in close contact with the inner wall of the vascular channel T, the auxiliary thrombectomy stent 4 will rub against the inner wall of the vascular channel during the dragging process, thereby enabling secondary capture of the embolus remaining on the inner wall of the vascular channel.

[0103] After thrombectomy is completed, the main thrombectomy stents 1 and 2 and the auxiliary thrombectomy stents 3 and 4 are retracted into the second tube G2 through the first tube G1, and finally the embolus captured by the main thrombectomy stents 1 and 2 and the auxiliary thrombectomy stents 3 and 4 is removed from the vascular channel T.

[0104] By using the aforementioned thrombectomy device, the main and auxiliary thrombectomy stents of different radial dimensions can work together to treat emboli in the center of the vascular channel and emboli adhering to the inner wall of the vascular channel in a graded manner. This can reduce the burden of capturing emboli in a single thrombectomy stent and reduce the number of thrombectomy procedures, thereby reducing the operational complexity of the thrombectomy process.

[0105] It is understood that the above embodiments provide multiple implementation schemes, and these implementation schemes can be combined and cross-referenced with each other without conflict, thereby extending to multiple possible implementation schemes. These can all be considered as the implementation schemes disclosed and made public in this application.

[0106] It should be noted that the terms "example" or "embodiment" used in this specification refer to a specific feature, structure, or characteristic that can be included in at least one implementation of the embodiments of the present invention. Furthermore, in the description of this specification, terms such as "first," "second," "third," and "fourth" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined with terms such as "first," "second," etc., may explicitly or implicitly include one or more of that feature. Moreover, terms such as "first," "second," "third," and "fourth" are used to distinguish similar objects and are not necessarily used to describe a specific order or indicate importance. It is understood that such terms can be interchanged where appropriate so that the embodiments of the present invention described herein can be implemented in orders other than those illustrated or described herein.

[0107] While the embodiments of the present invention have been disclosed above, the present invention is not limited thereto. Any person skilled in the art can make various modifications and alterations without departing from the spirit and scope of the present invention; therefore, the scope of protection of this specification should be determined by the scope defined in the claims.

Claims

1. A thrombus removal device, characterized in that, include: First tube and multiple main thrombectomy supports; The plurality of main thrombectomy brackets are sequentially arranged on the first tube along the axial direction of the first tube; Furthermore, along the axial direction of the first tube, the radial dimensions of the plurality of main thrombectomy supports increase sequentially; the main thrombectomy support with the smallest radial dimension is closer to the embolus, and along the axis of the first tube away from the embolus, the radial dimensions of the remaining main thrombectomy supports increase sequentially. The main thrombectomy support includes: a first part, a second part, and a third part; The first part is adapted to radially divide the embolus along the main embolic support. The first part includes a plurality of cutting members and a plurality of peeling members, wherein the two ends of the cutting members are at different distances from the axis of the main embolic support, so that the first part has a component distributed radially along the main embolic support. The combined projection of the plurality of peeling members on the cross-section of the main embolic support is circular, so that the first part has a component distributed circumferentially along the main embolic support. The second part is adapted to expand radially along the main thrombectomy bracket, and the second part includes a plurality of annular members, wherein the annular members are adapted to expand radially along the main thrombectomy bracket such that the second part has a circumferentially distributed component along the main thrombectomy bracket; The first and / or the second part are also adapted to circumferentially divide the embolus along the main embolic stent; The third part is adapted to collect the embolus after being cut by the first part and / or the second part. The third part is elastic and includes filters that are evenly distributed circumferentially along the main embolus support. A limiting part is provided on the first tube on the side of the third part away from the first part to effectively control the deformation of the third part in the axial direction of the first tube, so as to avoid excessive deformation of the third part. The thrombectomy device further includes a third tube and a secondary thrombectomy support; the third tube is coaxially disposed inside the first tube, and the relative position of the third tube and the first tube is adjustable; the secondary thrombectomy support is adapted to be coupled to the first tube; and / or, the secondary thrombectomy support is adapted to be coupled to the third tube, and there are multiple secondary thrombectomy supports, which are sequentially disposed on the third tube along the axial direction of the third tube, and the radial dimension of the secondary thrombectomy support includes at least two different radial dimensions, and the change in the radial dimension of the secondary thrombectomy support along the axial direction of the third tube is consistent with the change in the radial dimension of the multiple primary thrombectomy supports along the axial direction of the first tube.

2. The apparatus according to claim 1, characterized in that, The first part is fixedly connected to the first tube; The second part is fixedly connected to the first part and the third part, respectively.

3. The apparatus according to claim 2, characterized in that, The first part includes: A fastener adapted to be fixedly connected to the first tube.

4. The apparatus according to claim 2, characterized in that, The second part and the third part are integrally formed.

5. The apparatus according to claim 2, characterized in that, The second part and the third part are detachably and fixedly connected.

6. The apparatus according to claim 2, characterized in that, The third part includes: A sliding element, the sliding element being adapted to slide in conjunction with the first tube; The limiting portion is adapted to limit the distance by which the sliding member slides along the axial direction of the first tube.

7. The apparatus according to claim 1, characterized in that, The projection density of the first part on the cross-section of the main retrieval bracket is less than the projection density of the third part on the cross-section of the main retrieval bracket.

8. The apparatus according to claim 1, characterized in that, Also includes: The second tube is coaxially disposed outside the first tube, and the relative position of the second tube and the first tube is adjustable. The second tube is adapted to accommodate the main thrombec support.

9. The apparatus according to claim 8, characterized in that, The radial dimensions of the auxiliary thrombectomy brackets are the same.

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