工程化核酸酶及其应用

By mutating the amino acids of nucleases and binding them with heterologous engineered guide nucleic acids, and optimizing PAM preferences, the problem of insufficient flexibility and precision in targeted editing of nucleases in different organisms has been solved, enabling broader and more efficient genome editing.

CN116732003BActive Publication Date: 2026-07-17QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD
Filing Date
2023-01-30
Publication Date
2026-07-17

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Abstract

本公开内容提供了用于编辑活细胞的工程化核酸酶及其应用。
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