一种血管内超声探头的在体导航方法

By coating the surface of the IVUS probe with a superparamagnetic coating and using MPI technology for angiography, the problem of radiation damage caused by X-ray navigation has been solved, realizing radiation-free IVUS probe navigation and providing a safe intravascular imaging method.

CN116763357BActive Publication Date: 2026-07-17THE FIRST AFFILIATED HOSPITAL OF JINAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF JINAN UNIV
Filing Date
2023-06-07
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

The use of X-ray navigation in existing intravascular ultrasound imaging techniques for cardiovascular disease research has led to the problem of ionizing radiation damage to laboratory personnel and animals.

Method used

Magnetic particle imaging (MPI) technology is used for angiography and IVUS probe navigation. By coating the surface of the IVUS probe with a superparamagnetic coating, the MPI subsystem is used to achieve probe positioning and navigation without ionizing radiation.

Benefits of technology

It enables IVUS probe navigation under ionizing radiation-free conditions, avoiding radiation damage to laboratory personnel and animals, and providing a safe intravascular imaging solution.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明公开了一种基于磁粒子成像(Magneticparticleimaging，MPI)技术的血管内超声(IVUS)探头在体导航方法。本发明利用MPI对超顺磁性材料的快速成像方法，使用MPI技术导航带有磁性标记物的血管内IVUS探头实现无电离辐射伤害的血管内探测。实现本发明所述方法的装置由改造的IVUS子系统、MPI子系统和控制子系统组成。IVUS探头的端点或其它可用于标记探头位置的部位被涂上超顺磁性涂层，通过MPI子系统对探头标记物的实时成像，实现对IVUS探头的准确定位和血管内导航。控制子系统不仅控制MPI子系统和IVUS子系统的成像过程，也实时地处理MPI子系统和IVUS子系统的探测信号，并用以显示MPI和IVUS的影像，以便直观有效地导航IVUS探头的。本发明所述方法可实现无电离辐射伤害的IVUS血管探测，在血管疾病病理研究中有潜在应用价值。
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