Multi-frequency multi-mode modulation power ultrasonic high-frequency system and frequency adjusting method

Abstract

The application provides a multi-frequency multi-mode modulation power ultrasonic high-frequency system and a frequency adjusting method, which solves the problem of poor adaptability of a drive control circuit to frequency change and the like, and comprises the drive control circuit, the drive control circuit having a waveform signal generating circuit and a power amplification circuit, the drive control circuit being connected with the ultrasonic scalpel through a transducer, and the ultrasonic scalpel being connected with a bipolar circuit. The application has the advantages of good frequency adjusting adaptability, effective satisfaction of multi-frequency multi-mode power modulation requirements and the like.

Description

Technical Field

[0001] This invention belongs to the field of surgical ultrasonic scalpel technology, specifically relating to a multi-frequency, multi-mode modulated power ultrasonic high-frequency system and a frequency adjustment method. Background Technology

[0002] Electrosurgery is a surgical treatment method that uses the coagulation and ablation effects of high-frequency current. Generally, it works by conducting heat to the tissue or generating a thermal reaction in the tissue through the current. Common electrosurgery methods in dermatological surgery include electrocoagulation and electrocautery, similar to those used in general surgery. Ultrasonic scalpels, also known as high-intensity focused ultrasound (HIFU) therapy systems, are a thermotherapy method that coagulates and necrotizes tumors from outside the body. By focusing the energy of ultrasound at a single point, the temperature of the tissue at that focal point suddenly rises to 60-100°C. This temperature destroys and kills tumor tissue, achieving the goal of eliminating tumor cells. Normal tissue remains unaffected. However, when combining ultrasonic cutting with electrocoagulation hemostasis, existing drive control circuits have poor adaptability to frequency changes and cannot meet the requirements of multi-frequency, multi-mode power modulation.

[0003] To address the shortcomings of existing technologies, people have conducted long-term explorations and proposed various solutions. For example, Chinese patent literature discloses a highly integrated high-frequency ultrasonic system and its working method [202310098396.7], which includes a high-frequency ultrasonic scalpel connected to an ultrasonic transducer. The ultrasonic transducer is equipped with an ultrasonic high-frequency multi-frequency multi-mode integrated device. The high-frequency ultrasonic scalpel includes an ultrasonic guide rod connected to a composite handle. The bipolar circuit between the ultrasonic high-frequency multi-frequency multi-mode integrated device and the composite handle adopts a parasitic circuit structure and is connected to the ultrasonic circuit of the ultrasonic guide rod.

[0004] The above solution has solved the problem of combining ultrasonic cutting with electrocoagulation hemostasis to a certain extent, but it still has many shortcomings, such as poor adaptability to frequency conversion and inability to meet the requirements of multi-frequency and multi-mode power modulation. Summary of the Invention

[0005] The purpose of this invention is to address the above-mentioned problems by providing a well-designed, multi-frequency, multi-mode modulated power ultrasonic high-frequency system with good frequency conversion adaptability.

[0006] Another objective of this invention is to provide a frequency adjustment method that can meet the requirements of multi-frequency and multi-mode modulation, addressing the aforementioned problems.

[0007] To achieve the above objectives, the present invention adopts the following technical solution: a multi-frequency multi-mode modulated power ultrasonic high-frequency system, including a drive control circuit, the drive control circuit having a waveform signal generation circuit and a power amplification circuit, the drive control circuit being connected to an ultrasonic scalpel via a transducer, and the ultrasonic scalpel being connected to a bipolar circuit.

[0008] In the aforementioned multi-frequency multi-mode modulated power ultrasonic high-frequency system, the waveform signal generation circuit includes a microcontroller connected to a host computer via a serial port, the microcontroller being connected to a programmable module, and the programmable module outputting signals through a conversion unit.

[0009] In the aforementioned multi-frequency multi-mode modulated power ultrasonic high-frequency system, the programmable module includes a 12-bit shift register connected to a microcontroller and a conversion unit. The microcontroller is connected to the conversion unit in sequence through a 16-bit shift register, a 16-bit accumulator, a 16-bit latch, and a memory. The microcontroller adjusts the clock signal of the 16-bit latch through a frequency processing module.

[0010] In the aforementioned multi-frequency multi-mode modulated power ultrasonic high-frequency system, the conversion unit includes an amplitude D / A conversion module connected to a 12-bit shift register, a memory connected to a waveform high-speed D / A conversion module, the amplitude D / A conversion module providing a reference voltage to the waveform high-speed D / A conversion module, and the waveform high-speed D / A conversion module outputting a signal through a signal processing module.

[0011] In the aforementioned multi-frequency multi-mode modulated power ultrasonic high-frequency system, the power amplifier circuit includes a high-power operational amplifier U1. The negative input terminal of the high-power operational amplifier U1 is connected to the power supply circuit, the positive input terminal of the high-power operational amplifier U1 is grounded, and the output terminal of the high-power operational amplifier U1 is connected to the output circuit.

[0012] In the aforementioned multi-frequency multi-mode modulated power ultrasonic high-frequency system, the power supply circuit includes a socket J1 and a resistor RI connected between the socket J1 and the high-power operational amplifier U1. The negative input terminal of the high-power operational amplifier U1 is connected to a protection circuit, an absorption circuit, and a step-down circuit in parallel. The step-down circuit includes diodes D1 and D2 connected in series with ground. The absorption circuit includes diodes D3 and D4 connected in reverse series. The protection circuit includes a capacitor Cn and a resistor Rn connected in series.

[0013] In the aforementioned multi-frequency multi-mode modulated power ultrasonic high-frequency system, the output circuit includes a data interface J2 and diodes DFB1 and DFB2 connected between the data interface J2 and the high-power operational amplifier U1. A resistor RF is connected between the negative input terminal and the output terminal of the high-power operational amplifier U1, and a capacitor CF is connected in parallel with the resistor RF. The high-power operational amplifier U1 is connected to a phase compensation capacitor Cc and a current-limiting resistor Rcl. The positive terminal of the operational amplifier power supply of the high-power operational amplifier U1 is grounded through a diode DZ1, a capacitor E1, and a capacitor C1 connected in parallel, and the negative terminal of the operational amplifier power supply of the high-power operational amplifier U1 is grounded through a diode DZ2, a capacitor E2, and a capacitor C2 connected in parallel.

[0014] In the aforementioned multi-frequency multi-mode modulated power ultrasonic high-frequency system, the transducer uses piezoelectric ceramics to convert electrical energy into mechanical energy and employs an alternating cylindrical and variable cross-section for rigid connection.

[0015] In the aforementioned multi-frequency multi-mode modulated power ultrasonic high-frequency system, the bipolar circuit includes a power supply unit and a transformer unit connected to each other. The transformer unit is connected to the output unit through a vibration unit.

[0016] A frequency adjustment method for a multi-frequency, multi-mode modulated power ultrasound and high-frequency system includes the following steps:

[0017] S1: Divide the latch output address Dm-D0 into two parts: Dm-Dn and Dn-D0;

[0018] S2: Dm-D0 are connected to the waveform memory, while Dn-D0 remain unused;

[0019] S3: Control the frequency data Fin to vary between 0 and 2n.

[0020] Compared with existing technologies, the advantages of this invention are: the drive control circuit meets the requirements of high-efficiency vibration and a wide start-up bandwidth, and multi-mode mechanical oscillation under the drive of multiple modulation waves meets the requirements of multi-frequency and multi-mode power modulation; while realizing the ultrasonic scalpel function using the transducer, it can also realize the ultrasonic high-frequency bipolar function through the bipolar circuit, integrating the ultrasonic scalpel and high-frequency bipolar functions, reducing the complexity of the surgical procedure; the drive control circuit is applicable to any specific vibration structure, and its structure can be optimized without limitation within the bandwidth frequency domain. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the waveform signal generation circuit of the present invention.

[0022] Figure 2 This is a schematic diagram of the power amplifier circuit of the present invention.

[0023] Figure 3This is a schematic diagram of the drive control circuit of the present invention.

[0024] Figure 4 This is a schematic diagram of the method principle of the present invention.

[0025] As shown in the figure, the circuit includes: 1. Drive control circuit; 2. Waveform signal generation circuit; 3. Power amplifier circuit; 4. Transducer; 5. Ultrasonic scalpel; 6. Bipolar circuit; 7. Microcontroller; 8. Programmable module; 8. 12-bit shift register; 8. 16-bit shift register; 8. 16-bit accumulator; 8. 16-bit latch; 8. Memory; 85. Frequency processing module; 86. Conversion unit; 9. Amplitude D / A conversion module; 91. High-speed waveform D / A conversion module; 92. Signal processing module; 93. Detailed Implementation

[0026] The present invention will now be described in further detail with reference to the accompanying drawings and specific embodiments.

[0027] like Figure 1-3 As shown, a multi-frequency, multi-mode modulated power ultrasonic high-frequency system includes a drive control circuit 1, which can be excited in various operating modes to generate pulse repetition, phase, frequency, and amplitude modulated bulk wave excitation covering and sweeping across an extremely wide frequency band. This high-frequency and ultrasonic drive generates a uniform acoustic activity distribution on the surface and inside the vibration system, while avoiding the generation of stationary waves and standing waves, thus allowing the entire vibration system to respond fully. The drive control circuit 1 has a waveform signal generation circuit 2 and a power amplifier circuit 3. The drive control circuit 1 is connected to an ultrasonic scalpel 5 via a transducer 4, and the ultrasonic scalpel 5 is connected to a bipolar circuit 6. The transducer 4 or ultrasonic generator is a simple or hybrid constant-frequency contraction-extension vibration mode. This common oscillation mode can be described when one or more axial, lateral, or any other spatial dimension of the sensor periodically changes length according to some simple sinusoidal function. All conventional acoustic and high-frequency signal sources used for medium- and high-power applications require an oscillating electrical signal as input and generate a proportionally amplitude oscillating mechanical contraction / extension.

[0028] like Figure 1 As shown, the waveform signal generation circuit 2 includes a microcontroller 7 connected to a host computer via a serial port. This microcontroller receives data transmitted from the host computer and controls the amplitude and frequency of the synthesized waveform. The microcontroller 7 is connected to a programmable module 8, which outputs signals through a conversion unit 9. Using direct digital frequency synthesis (DDS) technology to synthesize analog waveform signals of different frequencies offers advantages such as fast frequency conversion and high stability, making it ideal as a signal source.

[0029] Specifically, programmable module 8 includes a 12-bit shift register 81 connected to microcontroller 7, and the 12-bit shift register 81 is connected to conversion unit 9. It sends amplitude data to amplitude D / A conversion module 91, whose analog output serves as the reference voltage for waveform high-speed D / A conversion module 92. Amplitude adjustment is achieved by changing the reference voltage. Microcontroller 7 is connected to conversion unit 9 sequentially through a 16-bit shift register 82, a 16-bit accumulator 83, a 16-bit latch 84, and memory 85. Microcontroller 7 adjusts the clock signal of 16-bit latch 84 through frequency processing module 86. Frequency adjustment can be achieved by changing the frequency control word of the DDS circuit to speed up the synthesized waveform, thereby changing the frequency. Optional frequency processing module 86 can multiply the clock signal to meet higher frequency requirements.

[0030] Furthermore, the conversion unit 9 includes an amplitude D / A conversion module 91 connected to a 12-bit shift register 81, and a waveform high-speed D / A conversion module 92 connected to the memory 85. The amplitude D / A conversion module 91 provides a reference voltage for the waveform high-speed D / A conversion module 92, and the waveform high-speed D / A conversion module 92 outputs a signal through the signal conditioning module 93.

[0031] The excitation voltage generated by the waveform signal generation section needs to be amplified to drive the ultrasonic scalpel vibration. For the applied voltage, the piezoelectric ceramic can be simplified as a capacitive load. There are two main types of voltage-controlled piezoelectric ceramic drive power supplies: one is a switching drive power supply based on the DC-DC converter principle, and the other is a DC amplification power supply. The former has lower power loss and higher efficiency, but larger power ripple and a narrower frequency response range; the latter has a wider frequency response range and can achieve a wider frequency adjustment range. Considering the low power requirement of the energy platform and the need for frequency adjustment, the power amplifier circuit 3 is selected to be a DC amplification method.

[0032] like Figure 2 As shown, the power amplifier circuit 3 includes a high-power operational amplifier U1. The negative input terminal of the high-power operational amplifier U1 is connected to the power supply circuit, the positive input terminal of the high-power operational amplifier U1 is grounded, and the output terminal of the high-power operational amplifier U1 is connected to the output circuit.

[0033] In addition, the power supply circuit includes socket J1 and resistor RI connected between socket J1 and high-power operational amplifier U1. The negative input terminal of high-power operational amplifier U1 is connected with a protection circuit, a snubber circuit and a buck circuit in parallel. The buck circuit includes diodes D1 and D2 connected in series with ground. The snubber circuit includes diodes D3 and D4 connected in reverse series. The protection circuit includes capacitor Cn and resistor Rn connected in series.

[0034] Meanwhile, the output circuit includes a data interface J2 and diodes DFB1 and DFB2 connected between the data interface J2 and the high-power operational amplifier U1. A resistor RF is connected between the negative input terminal and the output terminal of the high-power operational amplifier U1, and a capacitor CF is connected in parallel with the resistor RF. The high-power operational amplifier U1 is connected to a phase compensation capacitor Cc and a current limiting resistor Rcl. The positive terminal of the operational amplifier power supply of the high-power operational amplifier U1 is grounded through a diode DZ1, a capacitor E1, and a capacitor C1 connected in parallel, and the negative terminal of the operational amplifier power supply of the high-power operational amplifier U1 is grounded through a diode DZ2, a capacitor E2, and a capacitor C2 connected in parallel.

[0035] As can be seen, transducer 4 uses piezoelectric ceramics to convert electrical energy into mechanical energy. The frequency may be relatively constant, varying sufficiently to compensate for changes in temperature and load, or sometimes sweeping a narrow band around a central operating frequency. In contrast, high-power multi-frequency, multi-mode, modulated acoustic and ultrasonic systems can generate multimode mechanical oscillations over a very wide frequency range in any mechanical system. The oscillations of transducer 4 are not random but follow a consistent pulse repetition pattern, controlled by a system that modulates frequency, phase, and amplitude simultaneously. This avoids the generation of fixed waves or standing waves, resulting in high and low acoustic activity regions. Generator technology provides a high degree of freedom for the control, regulation, and programming of all vibration, frequency, and power parameters.

[0036] Clearly, the bipolar circuit 6 includes interconnected power supply units and transformer units, with the transformer unit connected to the output unit via the vibration unit. The bipolar circuit 6 can be combined with the drive control circuit 1 using a parasitic circuit structure, flexibly switching operating modes to meet the needs of complex surgical procedures. Both drive signals act on the same central rod of the ultrasonic scalpel, and the longitudinal vibration of the central rod is unaffected by the high-frequency bipolar signal. According to wave equation theory, the ultrasonic scalpel 5 rod contains not only longitudinal wave vibration modes but also lower-order bending vibrations and higher-order longitudinal-bending coupled vibrations. The vibration modes of the ultrasonic scalpel not only determine its operating frequency but also result in different displacement directions, interactions with biological tissues, and varying degrees of energy conversion. Therefore, using ultrasonic scalpels with different vibration modes to cut different biological tissues is more effective.

[0037] By effectively integrating the ultrasound system and the high-frequency system into a single device, the high-performance operation of the ultrasonic scalpel and the high-frequency bipolar system is ensured, reducing the space occupied during surgery. The system has a clear operating logic, is easy to operate, and can operate independently or output simultaneously in combination. The drive circuits do not interfere with each other, and the operating frequency is adjusted in a timely manner to ensure efficient operation.

[0038] Every elastic mechanical system has numerous vibration modes, plus harmonics and subharmonics in the ultrasonic and high-frequency domains. Many vibration modes are acoustically and / or mechanically coupled; others are relatively independent. The multimode acoustic and ultrasonic excitations described herein synchronously excite many vibration modes (including harmonics and subharmonics) in tissues and fluids, producing uniform, homogeneous, and repeatable high-intensity vibrations.

[0039] In addition, this application includes an ultrasonic resonant rod waveguide radiator having at least three cylindrical sections, one of which is an inlet section with a planar inlet surface and another is an outlet section with a planar outlet surface, and at least a variable cross section. The cylindrical and variable cross sections are arranged alternately and are acoustically rigidly connected to each other. The dimensions of the cylindrical and variable cross sections are selected such that the gain of the waveguide radiator is significantly greater than 1, and the strain generated by the ultrasonic waves passing through the waveguide radiator is minimized, increasing the operating lifetime of the waveguide radiator and maximizing the useful energy transmitted by the waveguide radiator. The dimensions of the cross sections are selected such that the exit and incident surfaces are approximately equal, and the length of the variable cross section is determined according to a specified formula, wherein the sum of the lengths of the exit cross section and adjacent cross sections is 30% or more of the total length of the waveguide radiator. This multi-frequency, multi-mode ultrasonic structure excitation is well-suited for driving slender structures with various loads and excitation forces, while maintaining optimal electroacoustic energy transmission efficiency in complex operating environments.

[0040] like Figure 4 As shown, a frequency adjustment method for a multi-frequency, multi-mode modulated power ultrasound and high-frequency system includes the following steps:

[0041] S1: Divide the latch output address Dm-D0 into two parts: Dm-Dn and Dn-D0;

[0042] S2: Dm-D0 are connected to the waveform memory, while Dn-D0 remain unused;

[0043] S3: The control frequency data Fin varies between 0 and 2n, and the increase in Dm-Dn data will not exceed 1. This ensures that data is read from the waveform data memory one by one, guaranteeing the accuracy of the output data. The change in Fin controls the rate of change of Dm-Dn data, adjusting the output waveform frequency. This changes the speed of the synthesized waveform while keeping the number of data points in the synthesized waveform constant. This avoids the problems of poor frequency stability when adjusting the frequency by changing the clock frequency, or poor waveform continuity when changing the number of synthesized waveform points, which are common problems in general frequency adjustment methods.

[0044] In summary, the principle of this embodiment is as follows: the drive control circuit 1 controls the vibration frequency of the ultrasonic scalpel, and in combination with the bipolar circuit 6, it meets the structural requirements of ultrasonic cutting and electrocoagulation hemostasis. The drive control circuit 1 uses direct digital frequency synthesis technology to synthesize analog waveform signals of different frequencies and uses them as signal sources, thereby meeting the requirements of multi-frequency and multi-mode power modulation.

[0045] The specific embodiments described herein are merely illustrative of the spirit of the invention. Those skilled in the art to which this invention pertains may make various modifications or additions to the described specific embodiments or use similar methods to substitute them, without departing from the spirit of the invention or exceeding the scope defined by the appended claims.

[0046] Although this paper frequently uses terms such as drive control circuit 1, waveform signal generation circuit 2, power amplifier circuit 3, transducer 4, ultrasonic scalpel 5, bipolar circuit 6, microcontroller 7, programmable module 8, 12-bit shift register 81, 16-bit shift register 82, 16-bit accumulator 83, 16-bit latch 84, memory 85, frequency processing module 86, conversion unit 9, amplitude D / A conversion module 91, waveform high-speed D / A conversion module 92, and signal processing module 93, the possibility of using other terms is not excluded. The use of these terms is merely for the convenience of describing and explaining the essence of this invention; interpreting them as any additional limitation would contradict the spirit of this invention.

Claims

1. A multi-frequency, multi-mode modulated power ultrasonic high-frequency system, comprising a drive control circuit (1), characterized in that, The drive control circuit (1) includes a waveform signal generation circuit (2) and a power amplifier circuit (3). The drive control circuit (1) is connected to an ultrasonic scalpel (5) via a transducer (4). The ultrasonic scalpel (5) is connected to a bipolar circuit (6). The waveform signal generation circuit (2) includes a microcontroller (7) connected to a host computer via a serial port. The microcontroller (7) is connected to a programmable module (8). The programmable module (8) outputs signals through a conversion unit (9). The power amplifier circuit (3) includes a high-power operational amplifier U1. The negative input terminal of U1 is connected to the power supply circuit, the positive input terminal of the high-power operational amplifier U1 is grounded, and the output terminal of the high-power operational amplifier U1 is connected to the output circuit. The power supply circuit includes a socket J1 and a resistor RI connected between the socket J1 and the high-power operational amplifier U1. The negative input terminal of the high-power operational amplifier U1 is connected to a protection circuit, a snubber circuit, and a step-down circuit in parallel. The step-down circuit includes diodes D1 and D2 connected in series to ground. The snubber circuit includes diodes D3 and D4 connected in reverse series. The protection circuit includes a capacitor Cn and a resistor Rn connected in series.

2. The multi-frequency, multi-mode modulated power ultrasonic high-frequency system according to claim 1, characterized in that, The programmable module (8) includes a 12-bit shift register (81) connected to the microcontroller (7) and the 12-bit shift register (81) is connected to the conversion unit (9). The microcontroller (7) is connected to the conversion unit (9) in sequence through a 16-bit shift register (82), a 16-bit accumulator (83), a 16-bit latch (84), and a memory (85). The microcontroller (7) adjusts the clock signal of the 16-bit latch (84) through the frequency processing module (86).

3. The multi-frequency multi-mode modulated power ultrasonic high-frequency system according to claim 2, characterized in that, The conversion unit (9) includes an amplitude D / A conversion module (91) connected to a 12-bit shift register (81), and a waveform high-speed D / A conversion module (92) connected to the memory (85). The amplitude D / A conversion module (91) provides a reference voltage to the waveform high-speed D / A conversion module (92), and the waveform high-speed D / A conversion module (92) outputs a signal through a signal processing module (93).

4. The multi-frequency multi-mode modulated power ultrasonic high-frequency system according to claim 1, characterized in that, The output circuit includes a data interface J2 and diodes DFB1 and DFB2 connected between the data interface J2 and the high-power operational amplifier U1. A resistor RF is connected between the negative input terminal and the output terminal of the high-power operational amplifier U1, and a capacitor CF is connected in parallel with the resistor RF. The high-power operational amplifier U1 is connected with a phase compensation capacitor Cc and a current limiting resistor Rcl. The positive terminal of the operational amplifier power supply of the high-power operational amplifier U1 is grounded through a diode DZ1, a capacitor E1, and a capacitor C1 connected in parallel. The negative terminal of the operational amplifier power supply of the high-power operational amplifier U1 is grounded through a diode DZ2, a capacitor E2, and a capacitor C2 connected in parallel.

5. A multi-frequency, multi-mode modulated power ultrasonic high-frequency system according to claim 1, characterized in that, The transducer (4) uses piezoelectric ceramics to convert electrical energy into mechanical energy and uses alternating cylindrical and variable cross sections for rigid connection.

6. The multi-frequency, multi-mode modulated power ultrasonic high-frequency system according to claim 1, characterized in that, The bipolar circuit (6) includes a power supply unit and a transformer unit connected to each other. The transformer unit is connected to the output unit through a vibration unit.

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