Double-layered cosmetic

Abstract

[Problem] To provide a two-layer cosmetic which has excellent two-layer stability, is good in separation, and is good in use properties such as stickiness. [Solution] A two-layer cosmetic containing: (A) one or more agents selected from the group consisting of 4-methoxysalicylic acid potassium salt, nicotinamide, ascorbyl glucoside, phenylethyl resorcinol, and 4-isobutylresorcinol; (B) an aqueous phase; and (C) an oil phase is used.

Description

Technical Field

[0001] This invention relates to double-layer cosmetics. Background Technology

[0002] Warming cosmetics provide a comfortable warming sensation, making them especially popular during the cold winter months. However, because they contain a large number of moisturizing agents with warming properties, they can be sticky when applied to the face and can cause significant skin irritation if left on without rinsing. Furthermore, to ensure the warming effect, they are formulated with almost no water in the ingredients, making it difficult to incorporate suitable extracts and active pharmaceutical ingredients.

[0003] To date, temperature-sensitive cosmetics containing tranexamic acid are known, and this tranexamic acid is mostly incorporated as an agent to improve rough skin or as a whitening agent (see Patent Document 1). However, temperature-sensitive cosmetics containing a pharmaceutical agent other than tranexamic acid as an active ingredient are completely unknown. Furthermore, non-sticky two-layer cosmetics containing a pharmaceutical agent other than tranexamic acid as an active ingredient are also completely unknown to date.

[0004] Existing technical documents

[0005] Patent documents

[0006] Patent Document 1: International Publication No. 2019 / 230579 Summary of the Invention

[0007] The inventors have surprisingly discovered that by including specific agents in a two-layer cosmetic product containing both an aqueous and an oil phase, it is possible to achieve a two-layer cosmetic product with excellent two-layer stability, good separability, and good usability, such as a non-sticky texture. This invention is based on these insights.

[0008] According to the present invention, the following invention is provided.

[0009] (1) A two-layer cosmetic product containing:

[0010] (A) One or more agents selected from the group consisting of potassium 4-methoxysalicylate, nicotinamide, ascorbate glucoside, phenylethyl resorcinol and 4-isobutylresorcinol;

[0011] (B) Aqueous phase; and

[0012] (C) Oil phase.

[0013] (2) The cosmetic according to (1), wherein the amount of water in the aqueous phase of (B) is less than 10% by mass relative to the total amount of the cosmetic.

[0014] (3) The cosmetic according to (1) or (2), wherein the aqueous phase of (B) contains a polyol.

[0015] (4) The cosmetic according to (3), wherein the aforementioned polyol comprises one or more selected from glycerin, dipropylene glycol, diglycerol, sorbitol, methyl glucetol polyether-10 and 1,3-butanediol.

[0016] (5) The cosmetic according to (3) or (4), wherein the amount of the aforementioned polyol is 40 to 70% by mass relative to the total amount of the cosmetic.

[0017] (6) The cosmetic according to any one of (1) to (5), wherein the cosmetic is a temperature-sensitive cosmetic.

[0018] (7) A cosmetic according to any one of (1) to (6), wherein the aforementioned (A) agent is potassium 4-methoxysalicylate, nicotinamide or phenylethyl resorcinol.

[0019] (8) The cosmetic product according to any one of (1) to (6), wherein,

[0020] The aforementioned agent (A) is potassium 4-methoxysalicylate, nicotinamide, ascorbate glucoside, or 4-isobutylresorcinol, and

[0021] The amount of 4-methoxysalicylate potassium salt, nicotinamide, ascorbate glucoside or 4-isobutylresorcinol in combination is 0.25 to 6% by mass relative to the total amount of cosmetic.

[0022] (9) The cosmetic product according to any one of (1) to (6), wherein,

[0023] The aforementioned agent (A) is phenylethyl resorcinol, and

[0024] The amount of phenylethyl resorcinol used in the cosmetic is less than 5% by mass relative to the total amount of the cosmetic product.

[0025] (10) The cosmetic product according to any one of (1) to (9), wherein,

[0026] The amount of surfactant incorporated is less than 0.01% of the total mass of the cosmetic product.

[0027] By using the double-layer cosmetic of the present invention, it is advantageous to provide a double-layer cosmetic with excellent double-layer stability, good separation properties, and good usability such as stickiness. Detailed Implementation

[0028] This invention provides a two-layer cosmetic product containing:

[0029] (A) One or more agents selected from the group consisting of potassium 4-methoxysalicylate, nicotinamide, ascorbate glucoside, phenylethyl resorcinol and 4-isobutylresorcinol;

[0030] (B) Aqueous phase; and

[0031] (C) Oil phase.

[0032] <Pharmaceuticals>

[0033] The agent contained in the double-layer cosmetic of the present invention is one or more agents selected from the group consisting of potassium 4-methoxysalicylate, nicotinamide, ascorbyl glucoside, phenylethyl resorcinol and 4-isobutylresorcinol.

[0034] Potassium 4-methoxysalicylate is a salicylic acid derivative and a compound that inhibits tyrosinase activity and melanin production.

[0035] Nicotinamide, also known as nicotinamide or nicotinic acid amide, is a derivative of nicotinic acid and is an amide compound of nicotinic acid (vitamin B3 / nicotinic acid). Nicotinamide is a water-soluble vitamin and a well-known component of the B vitamins. It can be extracted from natural sources (such as rice bran) or synthesized using known methods. For example, substances described in the 18th revision of the Japanese Pharmacopoeia can be used.

[0036] There is no particular limitation on ascorbyl glucoside, but L-ascorbyl glucoside is preferred. L-Ascorbyl glucoside is one of the derivatives of ascorbic acid, which is produced by the glycotransfer reaction of starch liquefaction liquid and L-ascorbic acid through cyclodextrin glucosyltransferase. After being applied to the skin, it is rapidly absorbed through the skin and converted into ascorbic acid (vitamin C) in the body. Therefore, it is widely used in topical skin agents that require whitening effects.

[0037] Phenethyl resorcinol is known as a skin-whitening ingredient synthesized based on pinoxolin (a polyphenol component) contained in the evergreen coniferous tree, Scots pine.

[0038] 4-Isobutylresorcinol has the effects of inhibiting melanin production and antibacterial properties. It is often found in cosmetics for whitening purposes and is useful as a whitening agent.

[0039] In a preferred embodiment of the double-layer cosmetic according to the present invention, the double-layer cosmetic comprises, as an agent, potassium 4-methoxysalicylate, nicotinamide, or phenylethyl resorcinol. Including these agents in the double-layer cosmetic of the present invention further improves the temperature-sensing effect and usability, and is therefore preferred in this respect.

[0040] A more preferred embodiment of the double-layer cosmetic according to the present invention is provided as follows: (A) the agent is potassium 4-methoxysalicylate, nicotinamide, ascorbyl glucoside or 4-isobutylresorcinol, and the amount of potassium 4-methoxysalicylate, nicotinamide, ascorbyl glucoside or 4-isobutylresorcinol is 0.25 to 6 by mass relative to the total amount of the cosmetic.

[0041] According to another preferred embodiment of the double-layer cosmetic of the present invention, a double-layer cosmetic is provided as follows: (A) the agent is phenylethyl resorcinol, and the amount of phenylethyl resorcinol is less than 5% by mass relative to the total amount of the cosmetic.

[0042] <Water Phase>

[0043] The aqueous phase in a two-layer cosmetic product can contain water, water-soluble alcohols, thickeners, etc., which are commonly used in cosmetics and pharmaceuticals. Furthermore, depending on the desired effect, moisturizers, chelating agents, preservatives, pigments, etc. can also be added.

[0044] The water contained in the double-layer cosmetic of the present invention is not particularly limited, and can include, for example, purified water, ion-exchanged water, tap water, etc.

[0045] The amount of water in the aqueous phase of the bilayer cosmetic of the present invention is not particularly limited, but preferably it is 10% by mass or less relative to the total amount of the cosmetic, more preferably it is 8% by mass or less relative to the total amount of the cosmetic, and even more preferably it is 7% by mass or less relative to the total amount of the cosmetic.

[0046] Examples of water-soluble alcohols include lower alcohols, polyols, polyol polymers, diol alkyl ethers, diethylene glycol alkyl ethers, diol ether esters, glycerol monoalkyl ethers, sugar alcohols, monosaccharides, oligosaccharides, polysaccharides and their derivatives, with polyols being preferred.

[0047] The amount of polyol in the aqueous phase of the bilayer cosmetic of the present invention is not particularly limited, but is preferably 40 to 70% by mass relative to the total amount of the cosmetic.

[0048] Examples of lower alcohols include ethanol, 1-propanol, isopropanol, isobutanol, and tert-butanol.

[0049] Examples of polyols include diols (e.g., dipropylene glycol, 1,3-butanediol, ethylene glycol, trimethylene glycol, 1,2-butanediol, tetramethylenediol, 2,3-butanediol, pentamethylenediol, 2-buten-1,4-diol, hexanediol, octanediol, etc.), triols (e.g., glycerol, trimethylolpropane, etc.), tetraols (e.g., diglycerol, pentaerythritol, etc.), pentaols (e.g., xylitol, triglycerides, etc.), hexaols (e.g., sorbitol, mannitol, etc.), and polyol polymers (e.g., diethylene glycol, dipropylene glycol- Triethylene glycol, polypropylene glycol, tetraethylene glycol, diglycerol-triglycerol, tetraglycerol, polyglycerol, etc.), diol alkyl ethers (e.g., ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monohexyl ether, ethylene glycol mono-2-methylhexyl ether, ethylene glycol isopentyl ether, ethylene glycol benzyl ether, ethylene glycol isopropyl ether, ethylene glycol dimethyl ether, ethylene glycol diethyl ether, ethylene glycol dibutyl ether, etc.), diethylene glycol alkyl ethers (e.g., diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monobutyl ether, diethylene glycol dimethyl ether, diethylene glycol diethyl ether, diethylene glycol butyl ether, diethylene glycol methyl ethyl ether, triethylene glycol monomethyl ether). Triethylene glycol monoethyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol monobutyl ether, propylene glycol isopropyl ether, dipropylene glycol methyl ether, dipropylene glycol ethyl ether, dipropylene glycol butyl ether, etc.), diol ether esters (e.g., ethylene glycol monomethyl ether acetate, ethylene glycol monoethyl ether acetate, ethylene glycol monobutyl ether acetate, ethylene glycol monophenyl ether acetate, ethylene glycol diadipate, ethylene glycol disuccinate, diethylene glycol monoethyl ether acetate, diethylene glycol monobutyl ether acetate, propylene glycol monomethyl ether acetate, propylene glycol monoethyl ether acetate, propylene glycol monopropyl ether acetate, propylene glycol monophenyl ether acetate, etc.), glycerol monoalkyl ethers (e.g.) Examples include squalene, squalene, squalene, etc.), sugar alcohols (e.g., maltotriose, mannitol, sucrose, erythritol, glucose, fructose, starch-degrading sugar, maltose, starch-degrading sugar reducing alcohol, etc.), glysolid, tetrahydrofurfuryl alcohol, POE-tetrahydrofurfuryl alcohol, POP-butyl ether, POP·POE-butyl ether trimeroxypropylene glycerol ether, POP-glycerol ether, POP-glycerol ether phosphate, POP·POE-pentaerythritol ether, polyglycerol, etc., preferably containing one or more selected from glycerol, dipropylene glycol, diglycerol, sorbitol, methylglucetol polyether-10 and 1,3-butanediol.

[0050] As monosaccharides, examples include tricarbon sugars (e.g., D-glyceraldehyde, dihydroxyacetone, etc.), tetracarbon sugars (e.g., D-erythrose, D-erythritol, D-threose, erythritol, etc.), pentose sugars (e.g., L-arabinose, D-xylose, L-lythose, D-arabinose, D-ribose, D-ribulose, D-xylulose, L-xylulose, etc.), and hexose sugars (e.g., D-glucose, D-tarose, D-alulose, D-galactose, D-fructose, L-galactose, L-mannose). Sugars, D-tagatose, etc.), heptoses (e.g., heptanose, heptose, etc.), octoses (e.g., octylulose, etc.), deoxyglucoses (e.g., 2-deoxy-D-ribose, 6-deoxy-L-galactose, 6-deoxy-L-mannose, etc.), aminoglucosides (e.g., D-glucosamine, D-galactosamine, sialic acid, aminouronic acid, muramic acid, etc.), uronic acids (e.g., D-glucuronic acid, D-mannuronic acid, L-glucuronic acid, D-galacturonic acid, L-iduronic acid, etc.), etc.

[0051] Examples of oligosaccharides include sucrose, gentiotriose, umbelliferone, galactose, plantain, isochorose, α,α-trehalose, raffinose, succinose, umbilicine, stachyose, and verbascosaccharides.

[0052] Examples of polysaccharides include cellulose, quince seed, starch, galactan, dermatan sulfate, glycogen, gum arabic, heparan sulfate-tragacanth gum, keratin sulfate, chondroitin, xanthan gum, guar gum, dextran, keratin sulfate, locust bean gum, and succinyl dextran.

[0053] Other examples of polyols include methyl glucoside polyoxyethylene ether (GLUCAM E-10) and methyl glucoside polyoxypropylene ether (GLUCAM P-10).

[0054] As natural water-soluble polymers, examples include plant-based polymers (e.g., gum arabic, astragalus gum, galactomannan, guar gum, carob gum, carrageenan, pectin, agar, quince seed (quince), sodium alginate (brown algae extract), starch (rice, corn, potato, wheat), glycyrrhizic acid), microbial polymers (e.g., xanthan gum, dextran, succinyl dextran, budding stalk polysaccharide, etc.), and animal-based polymers (e.g., collagen, casein, albumin, gelatin, etc.).

[0055] Examples of semi-synthetic water-soluble polymers include starch-based polymers (e.g., carboxymethyl starch, methyl hydroxypropyl starch, etc.), cellulose-based polymers (methyl cellulose, ethyl cellulose, methyl hydroxypropyl cellulose, hydroxyethyl cellulose, sodium cellulose sulfate, hydroxypropyl cellulose, carboxymethyl cellulose, sodium carboxymethyl cellulose, microcrystalline cellulose, cellulose powder, etc.), and alginate-based polymers (e.g., sodium alginate, propylene glycol alginate, etc.).

[0056] Examples of synthetic water-soluble polymers include ethylene-based polymers (e.g., polyvinyl alcohol, polyethylene methyl ether, polyvinylpyrrolidone, carboxyvinyl polymers, etc.), polyoxyethylene-based polymers (e.g., polyethylene glycol 20000, 40000, 60000, etc.), acrylic polymers (e.g., sodium polyacrylate, ethyl polyacrylate, polyacrylamide, etc.), polyethyleneimine, cationic polymers, etc.

[0057] Examples of moisturizers include chondroitin sulfate, hyaluronic acid, mucopolysaccharide sulfate, carboxylic acid, determinate collagen, 12-hydroxystearic acid cholesterol ester, sodium lactate, bile salts, DL-pyrrolidone carboxylate, short-chain soluble collagen, diglyceride (EO)PO adduct, Rosa roxburghii fruit extract, Achille melanoleucum extract, and Meliotus officinalis extract.

[0058] Examples of masking agents include 1-hydroxyethane-1,1-diphosphonic acid, tetrasodium 1-hydroxyethane-1,1-diphosphonic acid, disodium edetate, trisodium edetate, tetrasodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate, gluconic acid, phosphoric acid, citric acid, ascorbic acid, succinic acid, edetate, trisodium HEDTA, etc.

[0059] Examples of amino acids include neutral amino acids (e.g., threonine, cysteine, etc.) and basic amino acids (e.g., hydroxylysine, etc.). Examples of amino acid derivatives include sodium lauroyl sarcosinate (sodium lauroyl sarcosinate), acyl glutamate, sodium acyl β-alanine, and glutathione.

[0060] As pH adjusters, examples include buffers such as lactic acid-sodium lactate, citric acid-sodium citrate, and succinic acid-sodium succinate.

[0061] Examples of thickeners include xanthan gum, gum arabic, carrageenan, carrageenan, astragalus gum, carob gum, quince seed (Pyrus cydonia), casein, dextrin, gelatin, sodium pectate, sodium alginate, methylcellulose, ethylcellulose, CMC, hydroxyethylcellulose, hydroxypropylcellulose, PVA, PVM, PVP, sodium polyacrylate, carboxyvinyl polymer, locust bean gum, guar bean gum, tamarind (Tamarinus indica) seed gum, dialkyl dimethylammonium cellulose sulfate, magnesium aluminum silicate, bentonite, hydropyrite, AlMg silicate (VEEGUM), synthetic lithium saponite, and anhydrous silicate.

[0062] <Oil phase>

[0063] The oil phase components contained in the double-layer cosmetic of the present invention are not particularly limited, and can be listed as hydrocarbon oils, higher fatty acids, higher alcohols, synthetic ester oils, silicone oils, liquid oils, solid oils, waxes, fragrances, etc., which are commonly used in cosmetics, quasi-pharmaceuticals, etc.

[0064] Examples of hydrocarbon oils include isododecane, isohexadecane, isoparaffins, liquid paraffin, ceresin, squalane, pterosaurane, paraffin wax, pure ceresin, squalene, petrolatum, and microcrystalline wax.

[0065] Examples of high-grade fatty acids include lauric acid, myristic acid, palmitic acid, stearic acid, docosanoic acid, oleic acid, undecenoic acid, tall oil, isostearic acid, linoleic acid, linolenic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

[0066] Examples of higher alcohols include straight-chain alcohols (e.g., lauryl alcohol, cetyl alcohol, stearyl alcohol, docosanol, myristyl alcohol, oleyl alcohol, cetearyl alcohol, etc.) and branched-chain alcohols (e.g., monostearate glyceryl ether (squalyl alcohol)-2-decyltetradecanool, lanolin alcohol, cholesterol, phytosterol, hexyldodecanool, isostearyl alcohol, octyldodecanool, etc.).

[0067] Examples of synthetic ester oils include octyl octanoate, nonyl nonanoate, hexadecyl octanoate, isopropyl myristate, octyl dodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyldecyl dimethyl octanoate, cetyl lactate, myristyl lactate, acetylated lanolin, isocetyl stearate, isocetyl isostearate, cholesterol 12-hydroxystearate, ethylene glycol di(2-ethylhexanoate), dipentaerythritol fatty acid ester, N-alkyl diol monoisostearate, neopentyl glycol didecanoate, tripropylene glycol neopentanoate, diisostearate malate, glyceryl dihexyl undecanoate, glyceryl diisostearate, trimethylolpropane tri(2-ethylhexanoate), trimethylolpropane triisostearate, and pentaerythritol. Tetra(2-ethylhexanoate) ester, 2-ethylhexanoate triglyceride, tricaprylic acid glyceride, glyceryl triisopalmitate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate, 2-ethylhexyl palmitate, glyceryl trimyristate, glyceryl tri(2-heptylundecanoate), castor oil fatty acid methyl ester, oleyl alcohol oleate, acetylglycine ester, di(heptylundecanoate)palmitate, diisobutyl adipate, N-lauroyl-L-glutamic acid-2-octyldodecyl ester, di(2-heptylundecanoate)adipate, ethyl laurate, di(2-ethylhexyl) sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, 2-ethylhexyl succinate, triethyl citrate, etc., among which isopropyl myristate is preferred.

[0068] Examples of silicone oils include chain polysiloxanes (e.g., dimethyl polysiloxane (polydimethylsiloxane), methylphenyl polysiloxane, diphenyl polysiloxane, etc.), cyclic polysiloxanes (e.g., octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecylcyclohexylsiloxane, etc.), organosilicon resins forming a three-dimensional mesh structure, silicone rubber, various modified polysiloxanes (amino-modified polysiloxanes, polyether-modified polysiloxanes, alkyl-modified polysiloxanes, fluorinated polysiloxanes, etc.), acrylic organosilicones, etc., with dimethyl polysiloxane being the preferred choice among these.

[0069] Examples of liquid oils include avocado oil, camellia oil, turtle oil, macadamia seed oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, peach kernel oil, wheat germ oil, camellia oil, castor oil, flaxseed oil, safflower oil, cottonseed oil, perilla oil, soybean oil, peanut oil, tea seed oil, torreya nut oil, rice bran oil, tung oil, Japanese tung oil, jojoba oil, germ oil, and triglycerides, among which jojoba oil is preferred.

[0070] Examples of solid fats include cocoa butter, coconut oil, horse fat, hydrogenated coconut oil, palm oil, beef tallow, mutton tallow, hydrogenated beef tallow, palm kernel oil, lard, beef bone fat, Japanese wax kernel oil, hydrogenated oil, beef hoof oil, wild lacquer fruit wax, and hydrogenated castor oil.

[0071] Examples of waxes include beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, insect wax, whale wax, lignite wax, rice bran wax, lanolin, kapok wax, acetylated lanolin, lanolin oil, sugarcane wax, isopropyl lanolinate, hexyl laurate, hydrogenated lanolin, jojoba wax, hard lanolin, shellac wax, lanolin alcohol POE ether, lanolin alcohol POE acetate, cholesterol POE ether, polyethylene glycol lanolin ester, hydrogenated lanolin alcohol POE ether, etc.

[0072] As for fragrances, examples include natural fragrances derived from animals or plants, synthetic fragrances produced through chemical synthesis, and blended fragrances that are mixtures of these; there are no particular limitations. By combining fragrances, cosmetics with excellent fragrance longevity can be obtained.

[0073] As fragrance ingredients, specifically, the following can be listed: acetivenol, anisaldehyde, anethole, amyl acetate, amyl salicylate, gluconate, allyl hexanoate, aldehydes C6-20, asterolactone, muscone lactone, ambroxol, ionone, ambroxol, eugenol, nerolidin, galacin, citrulline, coumarin, geraniol, geraniol acetate, sandalwood secondary alcohol, sandalwood primary alcohol, sandela, cyclamen aldehyde, cis-3-hexenyl acetate, cis-3-hexenol, citral, citronellol acetate, citronellol, eucalyptol, dihydromyrcenol, jasmine lactone, cinnamyl alcohol, cinnamaldehyde, styrax acetate, cedrol, daumatone, daumatenone, decyl lactone, terpineol, terpineol, and tuna musk. Privet aldehyde, nerol, santalin, vanillin, hydroxycitronellol, phenethyl acetate, phenethyl alcohol, hexyl salicylate, acetylated vetiver oil, methyl dihydrojasmonate, piperaldehyde, neojasmonaldehyde, vertofix, benzyl acetate, benzyl salicylate, benzyl benzoate, pentalide, borneol acetate, myol, ketone musk, methyl anthranilate, methyl dihydrojasmonate, ethylnaphthyl methyl ether, lime oxide, linalyl acetate, linalool, limonene, neolimonaldehyde, limonaldehyde, rose oxide, rose alcohol, angelica oil, anise oil, artemisia oil, basil oil, laurel oil, bergamot oil, calamus oil, camphor oil, canaanca oil, cardamom oil, cinnamon oil (cassia) Oils including cypress oil, celery oil, chamomile oil, cinnamon oil, clove oil, coriander oil, cumin oil, dill oil, elemi oil, tarragon oil, eucalyptus oil, fennel oil, fenugreek oil, galangal oil, geranium oil, ginger oil, grapefruit oil, guaiac oil, cypress oil, juniper oil, mixed lavender oil, lavender oil, lemon oil, pearberry oil, orange oil, giraffe oil, silver acacia oil, peppermint oil, spearmint oil, and millet oil. Oils include: myrtle oil, nutmeg oil, oakmoss resin oil, frankincense essential oil, saposhnikovia root oil, sweet orange oil, parsley oil, patchouli oil, black pepper oil, perilla oil, orange leaf oil, neroli oil, lime oil, allspice oil, cinnamon oil, pine oil, rose oil, rosemary oil, sage oil, sandalwood oil, styrax oil, marigold oil, thyme oil, tuberose oil, valerian oil, vetiver oil, violet oil, wintergreen oil, artemisia oil, Iranian oil, sweet orange fruit oil, acacia amaranth absolute, broom absolute, hyacinth absolute, immortelle absolute, jasmine absolute, kalanchoe absolute, daffodil absolute, rose absolute, violet absolute, benzoin, etc.

[0074] <surfactants>

[0075] The two-layer cosmetic of the present invention, by incorporating agents such as potassium 4-methoxysalicylate, can ensure formulation stability by minimizing the use of surfactants typically incorporated in two-layer cosmetics for separation and surface stability. Therefore, the amount of surfactant incorporated in the two-layer cosmetic of the present invention is preferably less than 0.01% by mass relative to the total amount of the cosmetic.

[0076] In this specification, surfactants refer to ionic surfactants (anionic surfactants, cationic surfactants, and amphoteric surfactants) and nonionic surfactants. In addition to these four types of surfactants, polymeric surfactants, organosilicon surfactants, and natural surfactants are also included in the scope of surfactants in this specification.

[0077] <Other Ingredients>

[0078] In the double-layer cosmetic of the present invention, other ingredients commonly used in cosmetics, quasi-pharmaceuticals, etc., such as ultraviolet absorbers, powders, organic amines, polymer emulsions, vitamins, antioxidants, etc., can be appropriately added without impairing the effects of the present invention.

[0079] Examples of water-soluble ultraviolet absorbers include 2,4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, and 2-hydroxy-4-methoxybenzophenone-5-sulfonate. 4-Phenylacetone, 2-ethylhexyl-4'-phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octyloxybenzophenone, 4-hydroxy-3-carboxybenzophenone and other benzophenone-based ultraviolet absorbers; phenylbenzimidazole-5-sulfonic acid and its salts, phenylene-bis-benzimidazole-tetrasulfonic acid and its salts and other benzimidazole-based ultraviolet absorbers; 3-(4'-methylbenzylene)-d,l-camphor, 3-benzylene-d,l-camphor, uric acid, ethyl uric acid, etc.

[0080] Examples of oil-soluble ultraviolet absorbers include p-aminobenzoic acid (PABA), monoglyceride PABA ester, N,N-dipropoxy PABA ethyl ester, N,N-diethoxy PABA ethyl ester, N,N-dimethyl PABA ethyl ester, and N,N-dimethyl PABA butyl ester; anthranilic acid-based ultraviolet absorbers such as homonyl-N-acetyl-anthranilic ester; and amyl salicylate and methyl salicylate. Salicylic acid-based UV absorbers include: methyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, and p-isopropanol phenyl salicylate; octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, ethyl-2,4-diisopropyl cinnamate, methyl-2,4-diisopropyl cinnamate, propyl p-methoxycinnamate, isopropyl p-methoxycinnamate, isoamyl p-methoxycinnamate, and p-methoxycinnamate. Octyl cinnamate, 2-ethylhexyl-p-methoxycinnamate, 2-ethoxyethyl-p-methoxycinnamate, cyclohexyl p-methoxycinnamate, ethyl α-cyano-β-phenylcinnamate, 2-ethylhexyl-α-cyano-β-phenylcinnamate, glyceryl mono-2-ethylhexanoyl-di-p-methoxycinnamate, 3,4,5-trimethoxycinnamate 3-methyl-4-[methylbis(trimethylsiloxy)silyl]butyl] ester, etc. Cinnamic acid-based ultraviolet absorbers: 2-phenyl-5-methylbenzoxazole, 2,2'-hydroxy-5-methylphenylbenzotriazole, 2-(2'-hydroxy-5'-tert-octylphenyl)benzotriazole, 2-(2'-hydroxy-5'-methylphenylbenzotriazole, diphenylzazine, diphenylaminomethane, 4-methoxy-4'-tert-butyldibenzoylmethane, 5-(3,3-dimethyl-2-norbornene)-3-pent-2-one, octocrylene, etc.

[0081] Examples of powder components include, for instance, inorganic powders (e.g., talc, kaolin, mica, sericite, muscovite, phlogopite, synthetic mica, red mica, biotite, vermiculite, magnesium carbonate, calcium carbonate, aluminum silicate, barium silicate, calcium silicate, magnesium silicate, strontium silicate, tungstate metal salts, magnesium, silicon dioxide, zeolite, barium sulfate, and calcined calcium sulfate). Inorganic pigments include: gypsum, calcium phosphate, fluorapatite, hydroxyapatite, ceramic powder, metal soaps (e.g., zinc myristate, calcium palmitate, aluminum stearate), boron nitride, organic powders (e.g., polyamide resin powder (nylon powder), polyethylene powder, polymethyl methacrylate powder, polystyrene powder, styrene and acrylic copolymer resin powder, benzoguanamine resin powder, polytetrafluoroethylene powder, cellulose powder, etc.), inorganic white pigments (e.g., titanium dioxide, zinc oxide, etc.), inorganic red pigments (e.g., iron oxide (red lead), iron titanate, etc.), inorganic brown pigments (e.g., γ-iron oxide, etc.), inorganic yellow pigments (e.g., iron oxide yellow, loess, etc.), inorganic black pigments (e.g., iron oxide black, low-valent titanium dioxide, etc.), inorganic purple pigments (e.g., mango purple, cobalt purple, etc.), inorganic green pigments (e.g., chromium oxide, chromium hydroxide, cobalt titanate, etc.), and inorganic blue pigments (e.g., chromium oxide, chromium hydroxide, cobalt titanate, etc.). Examples of pigments include ultramarine and Prussian blue; pearlescent pigments (e.g., titanium dioxide cobalt mica, titanium dioxide cobalt bismuth oxychloride, titanium dioxide coated talc, colored titanium dioxide coated mica, bismuth oxychloride, fish scale foil, etc.); metallic powder pigments (e.g., aluminum powder, copper powder, etc.); and organic pigments such as zirconium, barium, or aluminum lake pigments (e.g., Red 201, Red 202, Red 204, Red 205, Red 220, Red 226, Red 228, Red 405, etc.). Organic pigments such as Orange 203, Orange 204, Yellow 205, Yellow 401, and Blue 404; Red 3, Red 104, Red 106, Red 227, Red 230, Red 401, Red 505, Orange 205, Yellow 4, Yellow 5, Yellow 202, Yellow 203, Green 3, and Blue 1; and natural pigments (e.g., chlorophyll, beta-carotene).

[0082] Examples of organic amines include monoethanolamine, diethanolamine, triethanolamine, morpholine, tetra(2-hydroxypropyl)ethylenediamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, and 2-amino-2-methyl-1-propanol.

[0083] Examples of polymeric emulsions include acrylic resin emulsions, ethyl polyacrylate emulsions, acrylic resin liquids, alkyl polyacrylate emulsions, polyvinyl acetate resin emulsions, and natural rubber latex.

[0084] Examples of vitamins include vitamins A, B1, B2, B6, C, E and their derivatives, pantothenic acid and its derivatives, biotin, etc.

[0085] Other possible complementary ingredients include, for example, preservatives (methylparaben, ethylparaben, butylparaben, phenoxyethanol, etc.), anti-inflammatory agents (e.g., glycyrrhizic acid derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, juniper alcohol, zinc oxide, allantoin, etc.), whitening agents (e.g., strawberry saxifrage extract, arbutin, etc.), and various extracts (e.g., Phellodendron bark, Coptis chinensis, Lithospermum erythrorhizon root, peony, Swertia japonica, birch, Sage, loquat, ginseng, aloe vera, mallow, iris root, grape, coix seed, loofah, white lily, saffron, Ligusticum chuanxiong, ginger root, and Dryopteris crassirhizoma). The ingredients include: Forsythia suspensa, Rhizoma rubra var. rubra, garlic, chili pepper fruit, Wenzhou mandarin orange peel, seaweed, etc.; activators (e.g., royal jelly, photosensitizers, cholesterol derivatives, etc.); blood circulation promoters (e.g., vanillin nonanoic acid, benzyl nicotinate, β-butoxyethyl nicotinate, capsaicin, gingerone, curcumin, ichthammol, tannic acid, α-camphol, tocopheryl nicotinate, inositol nicotinate, cyclomandelate, cinnarizine, tolazoline, acetylcholine, verapamil, strychnine, γ-oryzanol, etc.); anti-seborrheic agents (e.g., sulfur, dimethylthiazide, etc.); and anti-inflammatory agents (e.g., tranexamic acid, thiotaurine, linolenic acid, etc.).

[0086] Examples of antioxidants include tocopherols, butylated hydroxytoluene, butylated hydroxyanisole, and gallic acid esters.

[0087] Examples of acidification inhibitors include phosphoric acid, citric acid, ascorbic acid, maleic acid, malonic acid, succinic acid, fumaric acid, phospholipids, hexameta phosphate, phytic acid, and ethylenediaminetetraacetic acid.

[0088] According to a preferred embodiment of the present invention, a two-layer temperature-sensitive cosmetic (preferably a two-layer temperature-sensitive whitening lotion) can be provided, comprising: (A) one or more agents selected from the group consisting of potassium 4-methoxysalicylate, niacinamide, ascorbyl glucoside, phenylethyl resorcinol, and 4-isobutylresorcinol; (B) an aqueous phase; and (C) an oil phase. Examples of heat-generating substances that impart a temperature-sensitive effect include the aforementioned polyols, zeolites, metal salts, or metal oxides. These are all hygroscopic and generate heat upon contact with moisture on the skin, thereby providing a temperature sensation.

[0089] Example

[0090] The invention will be specifically described based on the following examples, but the invention is not limited to these examples. Unless otherwise specified, content is expressed as mass%.

[0091] Experimental Example 1

[0092] Regarding the two-layer cosmetics of Examples 1-11 and Comparative Examples 1-6 (refer to Tables 1 and 2), evaluations were conducted on "two-layer stability," "temperature sensitivity," "separability," and "usability (non-sticky feeling)." The evaluation methods for each evaluation were as described below. Furthermore, the evaluation results are shown in Tables 3 and 4 below.

[0093] (1) Two-layer stability

[0094] Regarding the bilayer cosmetics of Examples 1 to 11 and Comparative Examples 1 to 6 described below, the pharmaceutical agent, etc., can be uniformly dissolved in the aqueous phase. An oil phase is added, and then it is confirmed whether there is a uniform bilayer appearance (bilayer stability). The evaluation is based on the following criteria.

[0095] <Evaluation Criteria>

[0096] A: It can be modulated, no abnormalities were observed, and it is stable.

[0097] B: An anomaly and instability were observed during modulation.

[0098] (2) Temperature sensing effect

[0099] Regarding the two-layer cosmetics of Examples 1-11 and Comparative Examples 1-6 described below, a practical use test was conducted by 10 members of a professional panel. Specifically, the two-layer cosmetics prepared based on Tables 1 and 2 below were applied to the faces of each panel member, and the temperature sensation was evaluated based on the following criteria.

[0100] <Evaluation Criteria>

[0101] A: A professional team of 8 or more members confirmed that it has a warming effect.

[0102] B: A professional team of 5 to 8 members confirmed the presence of a warming effect.

[0103] C: A professional team of 3 to 5 members confirmed the presence of a warming effect.

[0104] D: When fewer than 3 members of the professional team confirmed the presence of a warming effect.

[0105] (3) Separability

[0106] After preparing and stirring the bilayer cosmetics of Examples 1-11 and Comparative Examples 1-6 described below, the time it took for the separated phase of the cosmetics to form a uniform layer up to about 10% was measured.

[0107] <Evaluation Criteria>

[0108] A: Separation occurred within 20 seconds but less than 30 minutes.

[0109] B: Separation occurs within 10 seconds to 20 seconds.

[0110] C: Separation occurs within 10 seconds or fails to separate after more than 30 minutes.

[0111] (4) Usability (non-sticky)

[0112] The two-layer cosmetics described in Examples 1 to 11 and Comparative Examples 1 to 6 were applied to the skin, and the presence or absence of stickiness was evaluated based on the following criteria.

[0113] <Evaluation Criteria>

[0114] A: Non-sticky, good usability

[0115] B: Less sticky and more usable

[0116] C: Highly sticky, poor usability

[0117] [Table 1]

[0118]

[0119] [Table 2]

[0120]

[0121] [Table 3]

[0122]

[0123] [Table 4]

[0124]

[0125] As can be seen from the results in Tables 3 and 4 above, the double-layer cosmetics within the scope of the present invention (Examples 1 to 11) have excellent double-layer stability, good separation properties and good usability compared with double-layer cosmetics outside the scope of the present invention (Comparative Examples 1 to 6).

[0126] Based on the results in Tables 3 and 4 above, when the amount of water in the aqueous phase of the two-layer cosmetic is less than 10% by mass relative to the total amount of the cosmetic, the two-layer cosmetics (Examples 1-4 and 6-11) included in the scope of the present invention also have good temperature-sensing effects.

Claims

1. A two-layer cosmetic product containing: (A) Select one or more from the group consisting of potassium 4-methoxysalicylate, nicotinamide, ascorbate glucoside, phenylethyl resorcinol and 4-isobutylresorcinol; (B) Aqueous phase; and (C) Oil phase, The amount of water in the aqueous phase (B) is less than 10% by mass relative to the total amount of the cosmetic. The aqueous phase (B) contains polyols. The amount of the polyol is 40-70% by mass relative to the total amount of the cosmetic product. The cosmetic product in question is a temperature-sensitive cosmetic product.

2. The cosmetic product according to claim 1, wherein, The amount of water in the aqueous phase (B) is less than 8% by mass relative to the total amount of the cosmetic.

3. The cosmetic product according to claim 1, wherein, The polyol comprises one or more selected from glycerol, dipropylene glycol, diglycerol, sorbitol, methyl glucetol polyether-10, and 1,3-butanediol.

4. The cosmetic product according to any one of claims 1 to 3, wherein, The (A) is potassium 4-methoxysalicylate, nicotinamide, or phenylethyl resorcinol.

5. The cosmetic product according to any one of claims 1 to 3, wherein, The (A) is potassium 4-methoxysalicylate, nicotinamide, ascorbate glucoside, or 4-isobutylresorcinol, and The amount of 4-methoxysalicylate potassium salt, nicotinamide, ascorbate glucoside or 4-isobutylresorcinol in combination is 0.25 to 6% by mass relative to the total amount of cosmetic.

6. The cosmetic product according to any one of claims 1 to 3, wherein, The (A) is phenylethyl resorcinol, and The amount of phenylethyl resorcinol used in the cosmetic is less than 5% by mass relative to the total amount of the cosmetic product.

7. The cosmetic according to any one of claims 1 to 3, wherein, The amount of surfactant incorporated is less than 0.01% of the total mass of the cosmetic product.

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