一株表皮葡萄球菌菌株SI-BP-02及其在抗菌中的应用

By screening and isolating Staphylococcus epidermidis strain SI-BP-02, the problem of bacterial resistance caused by existing antibiotic treatments has been solved, providing an effective means of inhibiting various drug-resistant microorganisms and achieving broad-spectrum antibacterial activity against drug-resistant bacteria.

CN116875486BActive Publication Date: 2026-07-17HEFEI INSTITUTE OF PHYSICAL SCIENCE CHINESE ACADEMY OF SCIENCES +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HEFEI INSTITUTE OF PHYSICAL SCIENCE CHINESE ACADEMY OF SCIENCES
Filing Date
2023-06-09
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Current antibiotic treatments lead to increased bacterial resistance, and there is a lack of effective means to combat multiple drug-resistant bacteria, making it difficult to cope with the threat of bacterial infections.

Method used

A Staphylococcus epidermidis strain, SI-BP-02, was screened and isolated. This strain exhibits antagonistic activity against a variety of drug-resistant and non-drug-resistant microorganisms and secretes broad-spectrum antibacterial substances, which can be used to prepare antibacterial agents.

Benefits of technology

This strain exhibits significant antibacterial activity against a variety of drug-resistant microorganisms, such as ESBLs-Escherichia coli, CRE-Escherichia coli, and MRSA, maintaining microbiome homeostasis and providing an effective means of combating drug-resistant bacteria.

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Abstract

本发明公开了一株表皮葡萄球菌菌株SI‑BP‑02及其在抗菌中的应用,属于微生物技术领域。该菌株的保藏编号为CCTCC NO:M 2023441。本发明的表皮葡萄球菌对多种耐药微生物和非耐药微生物具有较好的拮抗活性。有益效果:该菌株分泌了广谱抑菌物质,对常见的易导致感染性疾病的耐药菌和非耐药菌具有广谱抗菌活性,这为挖掘维持机体微生物组稳态的益生菌制剂打下基础。
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