Ophthalmic device

Abstract

An ophthalmic device includes a cannula having a cannula distal end, a lumen, and at least one fluid outlet. The cannula is configured to deliver a fluid. An envelope is disposed about the cannula and has an envelope distal end. A handle is coupled to the envelope and the cannula, the handle having an actuator. An internal mechanism is coupled to the actuator and is configured to retract the envelope relative to the cannula.

Description

[0001] Cross-reference to related applications

[0002] This application claims the benefit of U.S. Provisional Patent Application No. 63 / 136,031, filed January 11, 2021, entitled “OPHTHALMIC DEVICE”, the disclosure of which is incorporated herein by reference in its entirety. Technical Field

[0003] This disclosure generally relates to medical devices and procedures, and more specifically, to ophthalmic devices. Background Technology

[0004] Glaucoma is a disease caused by elevated intraocular pressure (IOP). IOP can increase when the eye's natural drainage mechanisms (e.g., the drainage of humic substances from the eye) are blocked, reduced, or otherwise obstructed. The cavity at the front (e.g., the top) of the lens of the eye is filled with a viscous fluid called aqueous humor. Aqueous humor supplies nutrients to the avascular parts of the eye (e.g., the cornea and lens) through continuous flow. This flow of aqueous humor also removes waste (e.g., foreign object debris) from these tissues. In a healthy eye, as the epithelial cells of the ciliary body secrete new aqueous humor, it flows through the trabecular meshwork out of the anterior chamber of the eye and into Schlemm's canal. The drained aqueous humor enters the venous bloodstream from the Schlemm's canal and leaves the eye with the venous blood. When the eye's natural drainage mechanisms (e.g., Schlemm's canal and / or the trabecular meshwork) cease to function properly, IOP begins to increase. Therefore, it is desirable to provide an ophthalmic device with a distal end for delivering fluid to the eye. Attached Figure Description

[0005] The accompanying drawings are included to provide a further understanding of the present disclosure and are incorporated in and constitute a part of this specification. The drawings illustrate embodiments of the present disclosure and, together with the specification, serve to explain the principles of the present disclosure.

[0006] Figure 1 A perspective view of an exemplary ophthalmic device according to aspects of this disclosure is depicted.

[0007] Figure 2 A perspective view of the distal end of an example ophthalmic device according to aspects of this disclosure is depicted, the ophthalmic device having an inner sleeve surrounded by a sheath.

[0008] Figure 3 Depicting aspects according to this disclosure Figure 2 A perspective view of the distal end of an ophthalmic device, in which the inner cannula protrudes from the sheath.

[0009] Figure 4A perspective view of the distal end of an example ophthalmic device according to aspects of this disclosure is depicted, showing an inner cannula protruding from the sheath.

[0010] Figure 5 A perspective view of the distal end of an example ophthalmic device according to aspects of this disclosure is depicted, showing an inner cannula protruding from the sheath.

[0011] Figure 6 Depicting aspects according to this disclosure Figure 5 A side view of an ophthalmic device.

[0012] Figure 7 A perspective view of the distal end of an example ophthalmic device according to aspects of this disclosure is depicted, showing an inner cannula protruding from the sheath.

[0013] Figure 8 Depicting aspects according to this disclosure Figure 7 Front view of an ophthalmic device.

[0014] Figure 9 A perspective view of the distal end of an example ophthalmic device according to aspects of this disclosure is depicted, showing an inner cannula protruding from the sheath.

[0015] Figure 10 A perspective view of the distal end of an example ophthalmic device according to aspects of this disclosure is depicted, showing an inner cannula protruding from the sheath.

[0016] Figure 11 A perspective view of the distal end of an example ophthalmic device according to aspects of this disclosure is depicted, showing an inner cannula protruding from the sheath. Detailed Implementation

[0017] The detailed description below is merely exemplary and interpretive, and not a limitation on the claimed features. As used herein, the terms “comprising,” “including,” or other variations are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements may include not only those elements but also other elements not expressly listed or inherent to such process, method, article, or apparatus. Additionally, the term “exemplary” is used herein in the sense of “example” rather than “ideal.” As used herein, the terms “about,” “substantially,” and “approximately” indicate a range of values ​​within + / - 5% of the stated value. The term “distal” refers to the portion furthest from the user when the device is introduced into the subject's body. In contrast, the term “proximal” refers to the portion closest to the user when the device is placed into the subject's body.

[0018] It should be understood that this disclosure includes examples of the subject matter and does not limit the scope of the appended claims. Various aspects of the subject matter will be disclosed based on specific, but not limiting, examples. The various embodiments described in this disclosure may be practiced in different ways and variations, and depending on the intended application and implementation.

[0019] The embodiments discussed below relate to a medical device, such as an ophthalmic device configured to treat glaucoma or other eye diseases, and related methods of use. According to some embodiments, the ophthalmic device may have a distal end including a cannula. The cannula may include an internal lumen and one or more outflow orifices configured to deliver a viscoelastic fluid or other substance to a target site on the patient, such as a Schlemm's cannula.

[0020] According to some embodiments, the end of the cannula may include a collar disposed around the outer surface of the cannula. The collar may be configured to interact with intraocular tissues in the aqueous humor outflow path of the patient's eye to facilitate cannula positioning or fluid transport relative to the eye. For example, the collar may include a radially projecting lip that is fixed or movable to a position adjacent to the orifice to provide a structure that facilitates positioning the orifice of the cannula within or near Schlemm's canal.

[0021] According to some embodiments, the collar can be implemented as part of a retractable sheath. The sheath can be positioned around the cannula and configured to retract relative to the cannula to pull patient tissue via a suction action. For example, an actuating button or other actuator component located on the handle of the device can be configured to retract the sheath to pull the trabecular mesh over and around the cannula, thereby penetrating the mesh with the cannula and opening the tube to facilitate fluid delivery therein.

[0022] According to some embodiments, the mechanism can be configured to retract the sheath or otherwise move components of the ophthalmic device with a relatively rapid and forceful biting motion. For example, such motion can facilitate aspiration and penetration of a patient's tissue through the cannula. Additionally or alternatively, the mechanism can operate a pump to inject fluid or substance through the cannula in conjunction with the retraction of the sheath.

[0023] The following text combines Figure 1-11 The specific examples shown discuss these and other embodiments. However, those skilled in the art will recognize various modifications and alternative applications. Therefore, the detailed description provided with reference to these figures and the description provided above should not be construed as limiting, but rather as an explanation of the various concepts associated with this disclosure.

[0024] Figure 1Examples of medical devices are shown, and more specifically, an example of ophthalmic device 10 is shown. In the examples shown, ophthalmic device 10 is configured as a medical device or minimally invasive surgical instrument, configured to interact with ocular tissue to facilitate the injection of substances into Schlem's canals or other intraocular sites of the patient's eye. However, although the examples herein are described with reference to ophthalmic instruments and procedures, it should be understood that the teachings of ophthalmic device 10 can be readily applied to or adapted to any of a variety of other medical and non-medical applications. For example, these may include other medical procedures involving interaction with patient tissues other than the patient's eye, and other non-medical applications involving the injection or delivery of fluids.

[0025] refer to Figure 1 The ophthalmic device 10 may include a handle 20 coupled to the ophthalmic component 30. The ophthalmic component 30 is generally configured for interaction with ocular tissues and / or insertion into intraocular cavities, such as the anterior chamber of a patient's eye. The ophthalmic component 30 may be configured to facilitate fluid delivery, tissue manipulation, and / or other interactions with the patient's eye.

[0026] like Figure 1 As illustrated in the examples, the eye component 30 may include an elongated tubular member projecting from the distal end of the handle 20 and defining a central longitudinal axis X. The eye component 30 may have a working length L and a diameter allowing insertion into the anterior chamber through a corneal incision or other incision in the patient's eye. The working length L described herein can be defined as the exposed length or distance of the eye component 30 projecting from the handle 20 to the distal end of the eye component 30. While other dimensions beyond these examples may be suitable in various embodiments, the working length L may, for example, range between approximately 16 mm and 40 mm, or more specifically, approximately 18 mm. While other dimensions beyond these examples may be suitable in various embodiments, the diameter may vary over the entire working length L, or may be constant over the entire working length L, and may range from, for example, approximately 100 micrometers (μm) to 1000 μm, or more specifically, approximately 700 μm. Figure 1 As shown in the example, eye component 30 may be implemented as a straight geometry (defining a straight central axis X), or eye component 30 may be implemented as a curved and / or bent geometry.

[0027] Continue to refer to Figure 1 The handle 20 can be implemented as the main body of the ophthalmic device 10 and can be configured to be operated by the hand of a user or other operator. For example, as Figure 1As shown, the handle 20 can be implemented as an elongated tubular member having a distal end and a proximal end opposite the distal end. This can, for example, facilitate a surgeon's gripping or manipulation of the handle 20 using a pencil gripper, although it is contemplated that the handle 20 can be implemented in other shapes and configurations, such as a pistol-shaped arrangement and / or a finger ring. The outer surface of the handle 20 may include a finger gripper 40 having a contoured shape and / or a textured surface (e.g., knurled, ribbed, or other surface texture) to facilitate a user's grip on the handle 20. Embodiments in which the outer surface of the handle 20 has a straight, non-contoured shape and / or a smooth outer surface are also contemplated.

[0028] Handle 20 may include or be coupled to actuator 50. Actuator 50 may be coupled to one or more moving parts of ophthalmic device 10 to provide one or more operational functions that facilitate the performance of ophthalmic surgery using the device. For example, actuator 50 may be configured to move one or more parts of ophthalmic component 30 independently of handle 20, and / or move two or more moving parts of ophthalmic component 30 independently of each other. Additionally or alternatively, actuator 50 may be configured to actuate pumps, plungers, and / or squeezing mechanisms for the transfer of fluid through ophthalmic component 30. Actuator 50 may, for example, be configured to move parts directly or via internal mechanisms provided in handle 20.

[0029] exist Figure 1 In the example shown, actuator 50 is implemented as, or otherwise includes, a mechanical button disposed on handle 20 and movable between an unpressed and a pressed position. The button is shown disposed on the lateral side of handle 20, which, for example, facilitates actuation by a surgeon or other user using their thumb and / or forefinger when handle 20 is held in the hand during surgery. Additionally or alternatively, embodiments are contemplated in which the button is disposed in other locations, such as, for example, the proximal end of the handle. Such embodiments are also contemplated in which, instead of or in addition to a button, actuator 38 includes a slider, roller, squeeze ball, and / or any other suitable mechanism that can be manipulated by a user or other operator to actuate moving parts of ophthalmic device 10.

[0030] Figure 2 and Figure 3 This is an enlarged view showing an example of an eye component 30 that may be included in an ophthalmic device 10. Figure 2 and Figure 3 As shown Figure 1 The distal portion 60 of the indicated eye component 30.

[0031] exist Figure 2 and Figure 3In the example shown, the eye component 30 includes a cannula 32 and a sheath 34 (sometimes referred to herein as a "shelter"). The sheath 34 is disposed around the cannula 32, and the cannula 32 is disposed within the sheath 34. The cannula 32 and the sheath 34 may, for example, each be implemented as substantially tubular components, wherein the cannula 32 is coaxially disposed with the sheath 34 and both the cannula 32 and the sheath 34 are disposed about a central axis X. The cannula 32 and / or the sheath 34 may, for example, each have a working length equal to the working length L of the eye component 30.

[0032] The sleeve 32 and the sleeve 34 can be configured for relative movement with respect to each other. For example, as... Figure 2 and Figure 3 As shown, the sleeve 32 and the cover 34 can be in the first configuration ( Figure 2 (as shown) and the second construction ( Figure 3 The sleeve 32 (as shown) can move relative to each other. In the first configuration, the distal end of the sleeve 32 is substantially covered or surrounded by the sleeve 34, and in the second configuration, the distal end of the sleeve 32 protrudes distally from the distal end of the sleeve 34. Relative movement can be achieved, for example, by retracting the sleeve 34 proximally independently of the sleeve 32 and the handle 20, and / or by deploying the sleeve 32 distally independently of the sleeve 34 and the handle 20. The actuator 50 can be operatively coupled to the sleeve 32 and / or the sleeve 34 to move the sleeve 32 and / or the sleeve 34 relative to a fixed part of the handle 20.

[0033] Cannula 32 can be configured to deliver fluids or other substances. For example, cannula 32 can be configured to inject viscoelastic fluids, such as sodium hyaluronate or chondroitin sulfate. Viscoelastic fluids are highly flexible gel-like materials that help provide sufficient space for adequate drainage and relieve eye pressure by causing tissue structures to expand away from each other, thereby reopening or expanding the flow path of aqueous humor. Viscoelastic fluids can also clear obstructed visual fields by causing bleeding structures to expand away from each other, thereby improving visibility. Cannula 32 is also envisioned for delivering stem cells, drugs, gases (such as SF6 or C3F8), and / or dyes (such as trypan blue dye). For example, injected stem cells can initiate the growth of healthy tissue within the eye (e.g., forming a healthy trabecular meshwork to enhance the drainage of aqueous humor through it). For example, injected dyes can flow through the trabecular meshwork to enhance the visualization of aqueous humor fluid flow, thereby identifying which areas of the trabecular meshwork, if present, remain blocked, collapsed, or otherwise impede the flow of aqueous humor. Furthermore, although examples of injecting substances are described, it is envisioned that the cannula 32 could be used additionally or alternatively to extract substances, such as tissue, blood, aqueous humor, or other substances from Schlemm's canal or other parts of the eye.

[0034] like Figure 3As shown, cannula 32 can be implemented as a blunt microcannula with a rounded, non-sharp, or otherwise injury-resistant tip at its distal end. While embodiments in which cannula 32 is implemented with a sharp needle or wound tip at its distal end are also contemplated, a blunt cannula can facilitate penetration of porous patient tissues, such as trabecular meshwork, while reducing the risk of unwanted trauma to surrounding tissues.

[0035] The cannula 32 may include one or more orifices 36 disposed on or near the distal portion of the cannula 32, for example, at or near the distal end of the cannula. One or more orifices 32 may provide one or more fluid transfer ports configured to transfer fluids or other substances. For example, one or more orifices 36 may be configured to provide an outflow port for delivering a viscoelastic substance to a patient's eye via a Schlemm's canal. Figure 3 As illustrated in the example, one or more orifices 36 may be provided on the lateral side of the sleeve 32, which can provide one or more fluid passages through the sidewall of the sleeve 32 in a direction transverse to the central axis X. Alternatively, other embodiments are contemplated, wherein the orifices are provided and / or provided at any other suitable location along the central axis X to transfer fluid to and / or from a intended target site. Each orifice 36 may have a diameter between 30 μm and 70 μm, or, for example, about 50 μm or about 60 μm, although other orifice diameters outside these ranges are contemplated to be suitably used in various embodiments. The sleeve 32 may include one or more grooves 38 provided on the distal portion of the sleeve 32.

[0036] For example, such as Figure 2 and Figure 3 As shown, the relative movement between the sleeve 34 and the casing 32 can be configured to selectively cover and expose one or more orifices 36 via the sleeve 34. For example, when in... Figure 2 In the first configuration shown, the distal end of the sleeve 34 can be positioned in a first axial position away from the orifice 36 to cover or surround the orifice 36, and when in... Figure 3 In the second configuration shown, the distal end of the sleeve 34 can be positioned in a second axial position adjacent to the orifice 36 so that the orifice 36 is exposed to the outside of the distal end of the sleeve 34.

[0037] The ophthalmic device 10 may also include a collar 70, which is disposed circumferentially around the end of the cannula 32 at or near the distal end of the cannula. For example, as Figure 2 and Figure 3As shown, the collar 70 may be an integral part of the sheath 34, or otherwise fixedly coupled to the sheath 34 at the distal end of the sheath, in which case the collar 70 may move together with the sheath 34, allowing the collar 70 and the cannula 32 to move relative to each other. The collar 70 may provide a structure arranged around the circumference of the cannula 32 (e.g., on or around the outer diameter of the cannula 32) configured to interact with patient tissue to facilitate placement of the cannula 32. For example, the collar face 72 at the distal end of the collar 70 may be configured to manipulate the trabecular mesh and / or provide guiding constraints to other tissue adjacent to the trabecular mesh and / or nearby Schlemm's canals. For example, such guiding constraints may help place the orifice 36 into the desired penetration depth within the cannula.

[0038] exist Figure 2 and Figure 3 In the example shown, the collar 70 is included as part of the distal portion of the sleeve 34. When the sleeve 34 and the tube 32 are in... Figure 3 In the second configuration shown, the collar surface 72 provides a lip that projects radially outward from the outer diameter of the sleeve 32. This lip may abut against the trabecular mesh or other structures adjacent to the Schlemm tube, such that when the device is in the second configuration, the penetration depth of the sleeve 32 is limited or guided by a predetermined distance between the distal end of the sleeve 32 and the lip (or the collar surface 72 or the distal end of the collar 70).

[0039] Figure 4 This is an enlarged view showing an example of an eye component 130 that may be included in an ophthalmic device 10. The cannula 132 and the sheath 34 may be similar to... Figure 2 The first and second configurations shown are movable relative to each other. In the first configuration, the distal end of the sleeve 132 is substantially covered or surrounded by the sleeve 34, and in the second configuration ( Figure 4 As shown, the distal end of the sleeve 132 protrudes distally from the distal end of the sleeve 34. The sleeve 132 has an outlet port 135 at its distal end, but no side orifices, such as the orifice 36 of the sleeve 32. In this document, fluid is delivered out of the outlet port 135 along the central longitudinal axis X. The sleeve 132 is shown as a straight sleeve.

[0040] Figure 5 and Figure 6 This is an enlarged view showing an example of an eye component 230 that may be included in the ophthalmic device 10. The cannula 232 and the sheath 34 can be similar to... Figure 2 The first and second configurations shown are movable relative to each other. In the first configuration, the distal end of the sleeve 232 is substantially covered or surrounded by the sleeve 34, and in the second configuration ( Figure 5As shown, the distal end of the sleeve 232 protrudes distally from the distal end of the sleeve 34. The sleeve 232 has an outlet port 235 at its distal end and one or more mousehole ports 236 extending proximally from the distal end of the sleeve 232. Hereinafter, fluid is delivered out of the outlet port 235 along the central longitudinal axis X, and typically out of the mousehole ports 236 in a direction perpendicular to the central longitudinal axis X. In some aspects of this disclosure, the mousehole ports 236 can be of any shape, such as square, rectangular, circular, triangular, etc.

[0041] Figure 7 and Figure 8 This is an enlarged view showing an example of an eye component 330 that may be included in the ophthalmic device 10. The cannula 332 and the sheath 34 may be similar to... Figure 2 The first and second configurations shown are movable relative to each other. In the first configuration, the distal end of the sleeve 332 is substantially covered or surrounded by the sleeve 34, and in the second configuration ( Figure 7 As shown), the distal end of the sleeve 332 protrudes distally from the distal end of the sleeve 34. The sleeve 332 has an outlet port 335 at the distal end of the sleeve 332, and one or more wires 336 extending through the outlet port 335.

[0042] In this disclosure, each end 337 of the wire 336 may be coupled or connected to a portion of the distal end of the sleeve 332, wherein the intermediate portion 338 of the wire may be bent around the outlet port 335. For example, the intermediate portion 338 may be configured to bend outward from the distal portion of the sleeve 332 to prevent coring of the rear wall of the Schlemm tube. Herein, fluid is delivered out of the outlet port 335 and along the central longitudinal axis X through the intermediate portion 338 of the wire 336. In some aspects of this disclosure, the wire 336 may be of any size and thickness.

[0043] In some aspects of this disclosure, such as Figure 9 As shown, multiple wires 336 can cross each other at the outlet port 335. For example, the first wire 336 can extend (e.g., bend outward) further from the distal end of the sleeve 332 than the second wire 336, thus allowing the first wire 336 to cross with the second wire 336. Figure 9 As shown, the wires 336 can be arranged orthogonally to each other in a cross shape. In this aspect of the disclosure, any number of wires 336 can be arranged on the sleeve 332. In this aspect of the disclosure, the wires 336 can cross each other in any suitable shape.

[0044] In some aspects of this disclosure, such as Figure 10As shown, multiple wires 336 can be arranged adjacent to each other on the outlet port 335, for example, in parallel. For instance, two wires 336 can be arranged parallel to each other on either side of the central longitudinal axis X, thereby dividing the outlet port 335 into three parts. In this disclosure, any number of wires 336 can be arranged on the sleeve 332. In this disclosure, the wires 336 can be arranged relative to each other at any position without crossing each other.

[0045] In some aspects of this disclosure, such as Figure 11 As shown, the multiple wires 336 disposed on the distal end of the sleeve 332 may include some wires disposed adjacent to each other without crossing each other (e.g., two parallel wires) and at least one wire that crosses at least one of the other wires (e.g., orthogonally crossing two parallel wires).

[0046] In one or more embodiments, the ophthalmic device includes a cannula having a distal end, a lumen, and at least one fluid outlet, the cannula being configured to deliver fluid; a suffix disposed around the cannula and having a distal end; a handle coupled to the suffix and the cannula, the handle having an actuator; and a retraction mechanism coupled to the actuator and configured to retract the suffix relative to the cannula.

[0047] In this aspect of the disclosure, the cannula is a straight tubular cannula arranged coaxially with the sheath along a central longitudinal axis. In this aspect of the disclosure, the distal end of the cannula is covered by the sheath in the inactive position of the ophthalmic device, and wherein the distal end of the cannula protrudes distally from the distal end of the sheath in the active position of the ophthalmic device. In this aspect of the disclosure, at least one fluid outlet includes a single outlet port disposed at the distal end of the cannula.

[0048] In this disclosure, at least one fluid outlet comprises: an outlet port disposed at a distal end of the sleeve; and one or more rat-hole ports disposed at the distal end of the sleeve and extending in a proximal direction along a portion of the sleeve. In this disclosure, the outlet port and one or more rat-hole ports form a continuous outlet. In some aspects of this disclosure, the continuous outlet is configured to deliver fluid out of the outlet port along a central longitudinal axis and to deliver fluid out of one or more rat-hole ports in a direction perpendicular to the central longitudinal axis. In this disclosure, at least one of the one or more rat-hole ports is an arched rectangular shape. In this disclosure, at least one of the one or more rat-hole ports is a square shape. In this disclosure, at least one of the one or more rat-hole ports is a rectangular shape. In this disclosure, at least one of the one or more rat-hole ports is a semi-circular shape.

[0049] In one aspect of this disclosure, a wire is disposed on the distal end of a bushing, wherein both ends of the wire are connected to the outer surface of the bushing, and the middle portion of the wire crosses a single outlet port. In another aspect of this disclosure, the middle portion of the wire arches outward beyond the distal end of the bushing. In another aspect of this disclosure, multiple wires are disposed on the distal end of a bushing, wherein for each wire, both ends are connected to the outer surface of the bushing, and the middle portion of the wire crosses a single outlet port. In another aspect of this disclosure, at least two of the multiple wires are disposed adjacent to each other. In another aspect of this disclosure, multiple wires are disposed adjacent to each other in parallel.

[0050] In this aspect of the disclosure, at least two of the plurality of wires are arranged to cross each other. In this aspect of the disclosure, a first wire of the two wires extends further outward from the distal end of the sleeve than a second wire of the two wires. In this aspect of the disclosure, the first and second wires of the plurality of wires are arranged adjacent to each other without crossing each other, and a third wire of the plurality of wires is arranged to cross at least one of the first and second wires. In this aspect of the disclosure, the actuator includes a button configured to: actuate to retract the sleeve relative to the sleeve; and actuate a fluid transfer mechanism to transfer fluid through the sleeve.

[0051] It should be understood that any particular order or hierarchy of the blocks in the disclosed process method is illustrative of the exemplary method. Based on design or implementation preferences, it should be understood that a particular order or hierarchy of the blocks in the process may be rearranged, or all of the shown blocks may be executed. In some implementations, any blocks may be executed simultaneously.

[0052] This disclosure is provided to enable those skilled in the art to practice the various aspects described herein. This disclosure provides various examples of the subject matter, and the subject matter is not limited to these examples. Numerous modifications to these aspects will be readily apparent to those skilled in the art, and the general principles defined herein can be applied to other aspects.

[0053] Unless otherwise expressly stated, elements referred to in the singular are not intended to mean "one and only one," but rather "one or more." Unless otherwise expressly stated, the term "some" refers to one or more. Masculine pronouns (e.g., his) include feminine and neuter genders (e.g., her and its), and vice versa. The use of titles and subtitles (if any) is for convenience only and does not limit the invention.

[0054] The term “exemplary” is used herein to mean “serving as an example or illustration.” Any aspect or design described herein as “exemplary” should not be construed as preferred or advantageous to other aspects or designs. In one respect, the various alternative configurations and operations described herein may be considered at least equivalent.

[0055] As used herein, the phrase "at least one" preceding a series of items (any items separated by the term "or") modifies the list as a whole, not each item within the list. The phrase "at least one" does not require the selection of at least one item; rather, it allows for the inclusion of at least one item from any given list, and / or at least one item from any combination of items, and / or at least one item from each list. For example, the phrase "at least one of A, B, or C" could refer to: only A, only B, or only C; or any combination of A, B, and C.

[0056] For example, phrases like "aspect" do not imply that such an aspect is essential to the present subject matter, or that such an aspect applies to all configurations of the present subject matter. Disclosure relating to an aspect may apply to all configurations or one or more configurations. An aspect may provide one or more examples. For example, phrases like "an aspect" may refer to one or more aspects, and vice versa. For example, phrases like "an embodiment" do not imply that such an embodiment is essential to the present subject matter, or that such an embodiment applies to all constructions of the present subject matter. Disclosure relating to an embodiment may apply to all embodiments or one or more embodiments. An embodiment may provide one or more examples. For example, phrases like "an embodiment" may refer to one or more embodiments, and vice versa. For example, phrases like "configuration" do not imply that such a configuration is essential to the present subject matter, or that such a configuration applies to all configurations of the present subject matter. Disclosure relating to a configuration may apply to all configurations or one or more configurations. A configuration may provide one or more examples. For example, phrases like "configuration" may refer to one or more configurations, and vice versa.

[0057] In one respect, unless otherwise stated, all measurements, numerical values, ratings, positions, sizes, dimensions, and other specifications set forth in this specification, including those in the appended claims, are approximate, not precise. In another respect, they are intended to have a reasonable range consistent with the functions they pertain to and with the custom of the art to which they belong.

[0058] It should be understood that the specific order or hierarchy of the disclosed steps, operations, or processes is an illustration of exemplary methods. It should be understood that the specific order or hierarchy of steps, operations, or processes can be rearranged based on design preferences. Some steps, operations, or processes may be performed simultaneously. Some or all of the steps, operations, or processes may be performed automatically without user intervention. The appended method claims (if any) present the elements of various steps, operations, or processes in an exemplary order and are not intended to limit one to the specific order or hierarchy presented.

[0059] All structural and functional equivalents of the elements throughout the various aspects described in this disclosure are known to or will be known hereafter to those skilled in the art, as expressly incorporated herein by reference and intended to be covered by the claims. Furthermore, the disclosure herein is not intended to be made public, whether or not such disclosure is expressly recited in the claims. No claim element shall be construed in accordance with 35 U.S.SC §112(f) unless it is expressly stated using the phrase “means for…” or, in the case of a method claim, using the phrase “for the step of…”. Moreover, with regard to the scope of the terms “comprising,” “having,” etc., such terms are intended to be inclusive in a manner similar to the term “including,” as interpreted when “including” is used as a transitional term in the claims.

[0060] The title, background, summary, description of the drawings, and abstract of this disclosure are incorporated herein by reference and are provided as illustrative examples rather than as limiting descriptions. This application is filed on the understanding that they will not be used to limit the scope or meaning of the claims. Furthermore, in the detailed description, it will be apparent that the description provides illustrative examples, and various features are combined in various embodiments to simplify the disclosure. This approach to disclosure should not be construed as reflecting an intention that the claimed subject matter requires more features than expressly stated in each claim. Rather, as reflected in the appended claims, the inventive subject matter lies in all features of fewer than those in a single disclosure configuration or operation. The appended claims are thus incorporated into the detailed description, wherein each claim is independently claimed as a separate subject matter.

[0061] The claims are not intended to be limited to the aspects described herein, but rather to conform to the full scope consistent with the language claims and to include all legal equivalents. Nevertheless, none of the claims are intended to include subject matter that fails to satisfy the requirements of 35 U.S.SC § 101, 102, or 103, nor should they be interpreted in this manner.

Claims

1. An ophthalmic device comprising: A casing having a distal end of the casing, a lumen and at least one fluid outlet, the casing being configured to deliver fluid; A sleeve, which is disposed around the sleeve and has a distal end of the sleeve; A handle, which is connected to the sleeve and the tube, the handle having an actuator; as well as A retraction mechanism, which is coupled to the actuator and configured to retract the sleeve relative to the sleeve. The at least one fluid outlet includes a single outlet port disposed at the distal end of the sleeve and a wire disposed at the distal end of the sleeve, wherein both ends of the wire are connected to the outer surface of the sleeve, and the middle portion of the wire intersects the single outlet port.

2. The ophthalmic device according to claim 1, wherein, The sleeve is a straight tubular sleeve, which is coaxially arranged with the sleeve along the central longitudinal axis.

3. The ophthalmic device according to claim 1, wherein, The distal end of the cannula is covered by the sheath in the non-activated position of the ophthalmic device, and wherein the distal end of the cannula protrudes distally from the distal end of the sheath in the activated position of the ophthalmic device.

4. The ophthalmic device according to claim 1, wherein, The at least one fluid outlet includes: An outlet port is provided at the distal end of the sleeve; and One or more mousehole ports are provided at the distal end of the sleeve and extend along a portion of the sleeve in the proximal direction.

5. The ophthalmic device according to claim 4, wherein, The outlet port and the one or more mouse hole ports form a continuous outlet.

6. The ophthalmic device according to claim 5, wherein, The continuous outlet is configured to deliver fluid out of the outlet port along the central longitudinal axis and to deliver fluid out of the one or more mousehole ports in a direction perpendicular to the central longitudinal axis.

7. The ophthalmic device according to claim 4, wherein, At least one of the one or more mousehole ports is an arched rectangular shape.

8. The ophthalmic device according to claim 4, wherein, At least one of the one or more mouse hole ports is square in shape.

9. The ophthalmic device according to claim 4, wherein, At least one of the one or more mouse hole ports is rectangular in shape.

10. The ophthalmic device according to claim 4, wherein, At least one of the one or more mouse hole ports is semi-circular in shape.

11. The ophthalmic device according to claim 1, wherein, The middle portion of the wire arches outward from the distal end of the sleeve.

12. The ophthalmic device of claim 1, further comprising a plurality of wires disposed at the distal end of the cannula, wherein for each wire, both ends of the wire are connected to the outer surface of the cannula, and the middle portion of the wire intersects the single outlet port.

13. The ophthalmic device according to claim 12, wherein, At least two of the multiple wires are arranged adjacent to each other.

14. The ophthalmic device according to claim 12, wherein, The multiple wires are arranged in parallel adjacent to each other.

15. The ophthalmic device according to claim 12, wherein, At least two of the multiple wires are arranged to cross each other.

16. The ophthalmic device according to claim 15, wherein, The first of the two wires extends further outward from the distal end of the sleeve than the second of the two wires.

17. The ophthalmic device according to claim 12, wherein, The first and second wires of the plurality of wires are arranged adjacent to each other without crossing each other, and the third wire of the plurality of wires is arranged to cross at least one of the first and second wires.

18. The ophthalmic device according to claim 1, wherein, The actuator includes a button, which is configured to one of the following: Actuation is used to retract the sleeve relative to the sleeve; as well as The fluid transfer mechanism is actuated to transfer fluid through the sleeve.

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