Sample collection device and endoscope

Abstract

The application relates to the technical field of endoscopes, and particularly provides a sample collection device and an endoscope. The sample collection device comprises an instrument plug, an end cover, a sampling container and a sealing plug. The instrument plug is provided with an instrument channel and a sample reservation channel which is in communication with the instrument channel. The two ends of the sample reservation channel are connected with the end cover and the sampling container respectively. The sealing plug is located in the sample reservation channel and connected with the end cover. The sampling container is configured to move into the sample reservation channel to be connected with the sealing plug when the sampling container is subjected to a pushing force. The connection strength between the sampling container and the sealing plug is greater than the connection strength between the end cover and the sealing plug. In the above scheme, when the biopsy forceps are withdrawn into the communication area of the instrument channel and the sample reservation channel, the biopsy forceps can be operated to be in an open state to release the tissue sample into the sampling container. At this time, the sampling container can be pushed to move into the sample reservation channel, so that the sampling container is connected with the sealing plug. The sealing plug can block the sampling container, and the tissue sample can be prevented from separating from the sampling container.

Description

Technical Field

[0001] The invention belongs to the field of endoscopy technology, and in particular relates to a sample collection device and an endoscope. Background Technology

[0002] With the continuous development of medical technology, endoscopes are increasingly widely used in diagnostic examinations, minimally invasive surgeries, and other fields. In related technologies, an endoscope includes an operating handle and an insertion section. In actual operation, by moving a lever on the operating handle, the traction wheel is rotated to adjust the posture of the curved section of the insertion section, thereby adjusting the orientation of the front module and enabling functions such as fixed-point observation.

[0003] In related technologies, endoscopes are typically used in conjunction with sample collection devices. For pathological effusions in the pleural, abdominal, and pelvic cavities, sputum, gastric juice, and urine samples need to be collected from the affected areas before and after treatment for analysis. This analysis helps select the appropriate treatment plan based on the severity of the patient's condition. However, sampling internal lesions requires inserting biopsy forceps for extraction. After extraction, the forceps are removed and placed in a sampling bottle. The extracted lesion tissue is inevitably exposed to the external environment, posing a high risk of human infection and environmental contamination. Summary of the Invention

[0004] This invention discloses a sample collection device and an endoscope to solve the technical problem of tissue samples being exposed to the external environment during biopsy forceps sampling in related technologies.

[0005] To solve the above problems, the present invention adopts the following technical solution: In a first aspect, this application provides a sample collection device for use in an endoscope. The sample collection device includes an instrument plug, an end cap, a sampling container, and a sealing plug. The instrument plug is provided with an instrument channel extending along its axial direction and a sample retention channel communicating with the instrument channel. The two ends of the sample retention channel are respectively connected to the end cap and the sampling container. The sealing plug is located in the sample retention channel and is connected to the end cap. The sampling container is configured to move into the sampling channel when it is pushed to switch from a first state to a second state. In the first state, the sampling container is separated from the sealing plug. In the second state, the sampling container is connected to the sealing plug, and the connection strength between the sampling container and the sealing plug is greater than the connection strength between the end cap and the sealing plug.

[0006] Furthermore, the instrument is provided with a first connecting part on the inner wall of the sample retention channel, and the sampling container is provided with a second connecting part on the outer wall. One of the first connecting part and the second connecting part is a snap-fit ​​protrusion, and the other is a snap-fit ​​recess. In the first state, the first connecting part and the second connecting part are snap-fitted together.

[0007] Furthermore, the inner wall of the sampling container is provided with anti-slip protrusions, which abut against the outer wall of the sealing plug when the sampling container is in the second state.

[0008] Furthermore, the sample collection device also includes a movable component, which is movably disposed within the sample retention channel. The movable component is provided with a sealing plug channel and an instrument perforation penetrating the sealing plug channel.

[0009] In the first state, the movable part abuts against the sampling container, and the sealing plug channel is connected to the sampling container. At least a portion of the sealing plug is located within the sealing plug channel, and the instrument perforation corresponds to the instrument channel. During the process of the sampling container switching from the first state to the second state, the sealing plug passes through the sealing plug channel, so that at least a portion of the sealing plug is contained within the sampling container to seal the opening of the sampling container.

[0010] Furthermore, the instrument is provided with a third connecting part on the inner wall of the sample retention channel, and the movable part is provided with a fourth connecting part on the outer wall. One of the third connecting part and the fourth connecting part is a snap-fit ​​protrusion, and the other is a snap-fit ​​recess. In the second state, the third connecting part and the fourth connecting part are snap-fitted together.

[0011] Furthermore, a diaphragm is provided at the opening of the sampling container, and a puncture member is connected to the movable part. When the sampling container switches from the first state to the second state, the puncture member is configured to puncture the diaphragm so that the sampling container is connected to the sample retention channel.

[0012] Furthermore, the puncture member includes an annular base and a puncture portion connected to the annular base. The puncture portion extends circumferentially along the annular base, and the ends of the puncture portion are spaced apart to form a gap region, so that the punctured diaphragm is connected to the sampling container through the portion corresponding to the gap region.

[0013] Furthermore, the puncture portion includes at least one puncture sub-portion, and the circumferential width of the puncture sub-portion gradually decreases in the puncture direction of the puncture portion, so that the end of the puncture portion forms a sharp tip.

[0014] Furthermore, when the puncture portion includes at least two puncture sub-portions, all the puncture sub-portions are connected end to end, and the puncture portion forms the gap region between the puncture sub-portion at the beginning and the puncture sub-portion at the end.

[0015] Secondly, this application provides an endoscope that includes the aforementioned sample collection device.

[0016] The technical solution adopted in this invention can achieve the following beneficial effects: The sample collection device and endoscope of this application allow the biopsy forceps to be operated in an open state when they are retracted into the area connecting the instrument channel and the sample retention channel. In this open state, the biopsy forceps can release tissue samples into the sampling container, thus achieving sample collection. After the tissue sample enters the sampling container, the operator can push the sample container into the sample retention channel, connecting it to the sealing plug. Because the connection strength between the sampling container and the sealing plug is greater than that between the end cap and the sealing plug, the connection between the sealing plug and the end cap is broken when the sampling container is removed, while the sealing plug remains connected to the sampling container. The sealing plug can seal the sampling container, preventing the tissue sample from detaching from it. Furthermore, if a pretreatment solution is provided in the sampling container, the sealing plug can prevent leakage of the pretreatment solution. Meanwhile, throughout the entire sampling and retention process, the biopsy forceps are not exposed to the external environment, which reduces the risk of personnel infection and environmental contamination, and also avoids the situation where the tissue sample taken by the biopsy forceps falls out, causing sampling failure. Furthermore, when retaining tissue samples, there is no need to operate the biopsy forceps to insert them into the dedicated sampling channel or sampling container again. When they appear in the connecting area between the instrument channel and the retention channel, the biopsy forceps can be operated to open them to complete the sampling. That is, the sample collection process can be carried out during the normal withdrawal of the biopsy forceps, which has the characteristics of convenient operation and stable and reliable sampling. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is one of the structural schematic diagrams of the sample collection device according to an embodiment of this application; Figure 2 This is a second schematic diagram of the sample collection device according to an embodiment of this application; Figure 3This is the third schematic diagram of the sample collection device according to an embodiment of this application; Figure 4 This is a schematic diagram showing the connection between the end cap and the sampling container and the instrument thimble in an embodiment of this application; Figure 5 yes Figure 4 A magnified view of a portion of point A in the middle; Figure 6 This is the fourth schematic diagram of the sample collection device according to an embodiment of this application; Figure 7 This is the fifth schematic diagram of the sample collection device according to an embodiment of this application; Figure 8 This is a schematic diagram of the structure of the active component in an embodiment of this application; Figure 9 This is a schematic diagram of the sample collection device according to an embodiment of this application before the puncture device is pierced; Figure 10 This is a schematic diagram of the sample collection device according to an embodiment of this application after the puncture device has punctured it; Figure 11 This is a schematic diagram of the puncture device according to an embodiment of this application; Figure 12 This is the sixth schematic diagram of the sample collection device according to an embodiment of this application; Figure 13 This is a schematic diagram of the structure of an endoscope according to an embodiment of this application.

[0019] In the picture: 100. Instrument plug; 110. Instrument channel; 120. Sample retention channel; 130. First connecting part; 140. Third connecting part; 200. End cap; 300. Sampling container; 310. Second connecting part; 320. Anti-slip protrusion; 330. Diaphragm; 400. Sealing plug; 500. Movable part; 510. Sealing plug channel; 520. Instrument perforation; 530. Fourth connecting part; 600. Puncture piece; 610. Annular base; 620. Puncture part; 621. Puncture sub-part; 630. Gap area; 700. Plug cap. Detailed Implementation

[0020] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be described in detail below. Obviously, the described embodiments are merely some embodiments of this invention, and not all embodiments. Based on the embodiments of this invention, all other implementation methods obtained by those skilled in the art without creative effort are within the scope of protection of this invention.

[0021] The terms "first," "second," etc., used in the specification and claims of this application are used to distinguish similar objects and not to describe a specific order or sequence. It should be understood that such use of data can be interchanged where appropriate so that embodiments of this application can be implemented in orders other than those illustrated or described herein, and the objects distinguished by "first," "second," etc., are generally of the same class and the number of objects is not limited; for example, a first object can be one or more. Furthermore, in the specification and claims, "and / or" indicates at least one of the connected objects, and the character " / " generally indicates that the preceding and following objects are in an "or" relationship.

[0022] In the various embodiments of this application, "near end" and "far end" refer to the distance of each component from the user in the usage environment. The end closer to the user is designated as the "near end", and the end farther from the user is designated as the "far end".

[0023] The following is in conjunction with the appendix Figures 1-13 The present application provides a detailed description of a sample collection device and endoscope through specific embodiments and application scenarios.

[0024] Please see Figures 1-3 This application discloses a sample collection device applied to an endoscope for collecting and retaining samples of internal human tissue obtained by a biopsy forceps. Specifically, the sample collection device includes an instrument stopper 100, an end cap 200, a sampling container 300, and a sealing plug 400. The instrument stopper 100 is provided with an instrument channel 110 extending along its axial direction. The distal end of the instrument channel 110 is used to connect with an instrument tube. The biopsy forceps can be inserted into the instrument channel 110 from the proximal end and enter the human body through the instrument tube to obtain diseased tissue. The instrument stopper 100 is also provided with a retention channel 120 that communicates with the instrument channel 110. The instrument channel 110 and the retention channel 120 together form a connected area, which can be considered as part of the instrument channel 110 or as part of the retention channel 120.

[0025] End cap 200 and sampling container 300 are respectively connected to both ends of sample retention channel 120. End cap 200 is located above sampling container 300. When the biopsy forceps containing lesion tissue retract to the area connecting instrument channel 110 and sample retention channel 120, the biopsy forceps can be operated to open the biopsy forceps, thereby releasing the tissue sample into sampling container 300 for collection and retention.

[0026] In the embodiments of this application, the sealing plug 400 is located in the sample retention channel 120 and connected to the end cap 200. The sampling container 300 is movably disposed in the sample retention channel 120. Specifically, the sampling container 300 is configured to move into the sample retention channel 120 when it is subjected to a thrust, so as to switch from a first state to a second state.

[0027] In the first state, the sampling container 300 is separated from the sealing plug 400. The connecting area formed by the instrument channel 110 and the sample retention channel 120 is located between the sampling container 300 and the sealing plug 400, so that the biopsy forceps can pass through or stay in the connecting area normally. When the biopsy forceps take the tissue sample and retract into the connecting area, the biopsy forceps can be operated to open and release the tissue sample. The tissue sample falls into the sampling container 300. That is to say, the sampling container 300 can contain the tissue sample released by the biopsy forceps in the first state.

[0028] After the sample collection is completed, a pushing force is applied to the sampling container 300 to move it within the sample retention channel 120, thereby switching from the first state to the second state. In the second state, the sampling container 300 moves to a position where it is connected and fixed to the sealing plug 400, and the connection strength between the sampling container 300 and the sealing plug 400 is greater than the connection strength between the end cap 200 and the sealing plug 400. When a pulling force is applied to the sampling container 300, the sampling container 300 can switch from the second state to the first state, and continuing to apply the pulling force can completely pull the sampling container 300 away from the instrument plug 100.

[0029] Based on the above technical solution, after the tissue sample taken by the biopsy forceps is released into the sampling container 300, a pulling force is applied to the sampling container 300 to switch the sampling container 300 from the second state to the first state or to completely detach it from the instrument plug 100. Because the connection strength between the sealing plug 400 and the end cap 200 is less than the connection strength between the sealing plug 400 and the sampling container 300, the connection state between the sealing plug 400 and the end cap 200 is broken, while the connection state between the sealing plug 400 and the sampling container 300 is still maintained. The sealing plug 400 can seal the opening of the sampling container 300 to prevent the tissue sample from falling out of the sampling container 300. When the sampling container 300 is filled with pretreatment liquid, the sealing plug 400 can prevent the leakage of the pretreatment liquid.

[0030] Meanwhile, throughout the entire sampling and retention process, the biopsy forceps are not exposed to the external environment, which reduces the risk of personnel infection and environmental contamination, and also avoids the situation where the tissue sample taken by the biopsy forceps falls out, causing sampling failure. Furthermore, when retaining tissue samples, there is no need to operate the biopsy forceps to insert them into the dedicated sampling channel or sampling container again. The biopsy forceps only need to perform a normal withdrawal action. When it appears in the connecting area between the instrument channel 110 and the retention channel 120, the biopsy forceps can be operated to open it to complete the sampling. It has the characteristics of convenient operation and stable and reliable sampling.

[0031] Please see Figure 4 and Figure 5 The instrument stopper 100 has a first connecting portion 130 on the inner wall of the sample retention channel 120, and the sampling container 300 has a second connecting portion 310 on the outer wall. Through the connection between the first connecting portion 130 and the second connecting portion 310, the sampling container 300 can be fixedly connected to the instrument stopper 100 in a first state. Specifically, one of the first connecting portion 130 and the second connecting portion 310 is a snap-fit ​​protrusion, and the other is a snap-fit ​​recess. In the first state, the first connecting portion 130 and the second connecting portion 310 are snap-fitted together.

[0032] During the research process, the inventors discovered that the instrument plug 100 is usually made of elastic material, such as rubber or silicone. If the snap-fit ​​protrusion is provided on the sampling container 300 and the snap-fit ​​recess is provided on the inner wall of the sample retention channel 120, then when the sampling container 300 switches from the first state to the second state, the inner wall of the sample retention channel 120 will always be in close contact with the snap-fit ​​protrusion on the sampling container 300. The channel section of the sample retention channel 120 through which the snap-fit ​​protrusion passes will be deformed in sequence to produce a recess that matches the snap-fit ​​protrusion. The movement of the entire sampling container 300 is subject to greater resistance.

[0033] Based on the above, in some embodiments of this application, the first connecting part 130 is a snap-fit ​​protrusion, and the second connecting part 310 is a snap-fit ​​recess. That is, the snap-fit ​​protrusion is provided on the inner wall of the sample retention channel 120, and the snap-fit ​​recess is provided on the sampling container 300. In this way, when the sampling container 300 switches from the first state to the second state, the snap-fit ​​protrusion in the instrument thimble 100 only slides with the outer surface of the sampling container 300, and the snap-fit ​​protrusion can undergo adaptive deformation without the inner wall of the sample retention channel 120 needing to generate a matching recess structure to follow the movement of the snap-fit ​​protrusion. This makes the force on the sampling container 300 less when it moves, and can improve the smoothness of the operator pushing and pulling the sampling container 300.

[0034] As can be seen from the foregoing, the connection strength between the sampling container 300 and the sealing plug 400 is greater than the connection strength between the end cap 200 and the sealing plug 400. For example, the sealing plug 400 and the end cap 200 can be connected and fixed by magnetic attraction. When the sampling container 300 switches from the first state to the second state, at least a portion of the sealing plug 400 can be inserted into the sampling container 300 in a tight fit to achieve connection and fixation with the sampling container 300 and block the opening of the sampling container 300. When a pulling force is applied to the sampling container 300 to move it, the magnetic connection between the sealing plug 400 and the end cap 200 is released.

[0035] For further technical solutions, please refer to Figure 5 The inner wall of the sampling container 300 is provided with anti-slip protrusions 320. When the sampling container 300 is in the second state, the anti-slip protrusions 320 abut against the outer wall of the sealing plug 400. In this way, the friction between the sampling container 300 and the sealing plug 400 can be increased, and the connection strength between the sampling container 300 and the sealing plug 400 can be strengthened.

[0036] For some embodiments of this application, please refer to Figures 6-8 The sample collection device also includes a movable part 500, which is a cylindrical structure with a sealing plug channel 510 and an instrument perforation 520 through the sealing plug channel 510. The movable part 500 is movably disposed in the sample retention channel 120. Specifically, the movable part 500 is movably disposed between the end cap 200 and the sampling container 300.

[0037] In the first state, please refer to Figure 6 When the movable part 500 abuts against the sampling container 300, the sealing plug channel 510 is connected to the sampling container 300, and the instrument perforation 520 corresponds to the instrument channel 110. The biopsy forceps can pass through the instrument perforation 520 to enter or withdraw from the human body. The biopsy forceps can release tissue samples in the sealing plug channel 510, and the tissue samples can fall into the sampling container 300. Since the movable part 500 abuts against the sampling container 300, the tissue samples can be prevented from falling onto the end face of the sampling container 300, thereby ensuring that the tissue samples released by the biopsy forceps fall stably into the sampling container 300.

[0038] During the process of applying a pushing force to the sampling container 300 to switch the sampling container 300 from the first state to the second state, the sampling container 300 can push the movable part 500 to move together. The sealing plug channel 510 of the movable part 500 can avoid the sealing plug 400. After the sealing plug 400 completely passes through the sealing plug channel 510, the sealing plug 400 moves and inserts into the sampling container 300, and seals the opening of the sampling container 300.

[0039] In the second state, please see Figure 7The movable part 500 is connected and fixed to the inner wall of the sample retention channel 120 to prevent it from falling out of the sample retention channel 120 after the sampling container 300 is removed. At least part of the sealing plug 400 is contained in the sampling container 300 to block the opening of the sampling container 300. At this time, the movable part 500 can limit the sampling container 300 to prevent the sampling container 300 from moving excessively into the sample retention channel 120 and falling completely into the sample retention channel 120.

[0040] For some embodiments of this application, please refer to Figure 6 and Figure 8 The instrument plug 100 is provided with a third connecting part 140 on the inner wall of the sample retention channel 120, and the movable part 500 is provided with a fourth connecting part 530 on the outer wall. One of the third connecting part 140 and the fourth connecting part 530 is a snap-fit ​​protrusion, and the other is a snap-fit ​​recess. In the second state, the third connecting part 140 and the fourth connecting part 530 snap-fit ​​together to realize the connection and fixation between the movable part 500 and the instrument plug 100.

[0041] It should be understood that, in the second state, the sampling container 300 has a portion exposed outside the sample retention channel 120, which facilitates applying a pulling force to the sampling container 300 to pull it away from the instrument plug 100; similarly, in the second state, the sealing plug 400 has a portion exposed outside the sampling container 300, which facilitates applying a pulling force to the sealing plug 400 to pull it away from the sampling container 300 after the sampling container 300 is removed from the sample retention channel 120, thereby removing the tissue sample from the sampling container 300.

[0042] In some embodiments of this application, the sampling container 300 may be pre-filled with a pretreatment solution, which can pre-treat the tissue sample, simplify the subsequent processing steps of the tissue sample, and save the processing time of the tissue sample. For example, the pretreatment solution may be physiological saline or disinfectant.

[0043] During the assembly of the entire sample collection device, if the sampling container 300 is pre-filled with pretreatment liquid, the pretreatment liquid in the sampling container 300 may spill from the opening during the movement of the sample collection device. Based on this, a diaphragm 330 is provided at the opening of the sampling container 300. In the first state, the diaphragm 330 can seal the sampling container 300 to prevent the pretreatment liquid in the sampling container 300 from overflowing.

[0044] In some embodiments of this application, the movable component 500 is connected to a puncture component 600. When the sampling container 300 switches from a first state to a second state, the puncture component 600 is configured to puncture the diaphragm 330, thereby connecting the sampling container 300 to the sample retention channel 120. Based on this technical solution, in the first state, the tissue sample released by the biopsy forceps will first fall onto the diaphragm 330. When the sampling container 300 switches from the first state to the second state, the puncture component 600 punctures the diaphragm 330 to form a rupture, allowing the tissue sample on the diaphragm 330 to fall into the sampling container 300 through the rupture.

[0045] For some embodiments of this application, please refer to Figures 9-11 The puncture member 600 includes an annular base 610 and a puncture portion 620 connected to the annular base 610. The annular base 610 is connected and fixed to the movable member 500. Exemplarily, the annular base 610 can be connected and fixed to the movable member 500 by means of adhesion, snap-fit, or threaded connection, etc., which is not limited in this application. The puncture portion 620 is connected to the side of the annular base 610 facing the sampling container 300. The puncture portion 620 extends circumferentially along the annular base 610, and the beginning and end of the puncture portion 620 are spaced apart to form a gap region 630. In this way, when the puncture device 600 punctures the diaphragm 330, the portion of the diaphragm 330 that does not correspond to the gap region 630 is continuously cut by the circumferentially extending puncture portion 620, ensuring that the diaphragm 330 can stably form a larger opening for tissue samples to fall into the sampling container 300. On the other hand, the portion of the diaphragm 330 that corresponds to the gap region 630 remains connected to the sampling container 300, that is, the diaphragm 330 is connected to the opening of the sampling container 300 without breaking, avoiding the formation of diaphragm fragments that fall into the sampling container 300 and affect the subsequent removal of tissue samples from the sampling container 300.

[0046] In some embodiments of this application, the puncture portion 620 can be a circumferentially non-closed annular thin-walled structure (not shown in the figure). The end of the puncture portion 620 facing the sampling container 300 can be a sharp blade. When the puncture member 600 comes into contact with the diaphragm 330, the blade is squeezed against the diaphragm 330 and cuts through the diaphragm 330, thereby creating a rupture.

[0047] In some embodiments of this application, the puncture portion 620 may include a puncture sub-portion 621, which is a thin-walled structure (not shown) extending circumferentially along the annular base 610. In the puncture direction of the puncture member 600, the circumferential width of the puncture sub-portion 621 gradually decreases, so that the end of the puncture sub-portion 621 forms a sharp tip, thereby facilitating the puncture of the diaphragm 330.

[0048] For some embodiments of this application, please refer to Figure 11The puncture portion 620 may also include at least two puncture sub-portions 621. When the puncture portion 620 includes at least two puncture sub-portions 621, all the puncture sub-portions 621 are connected end to end. In this way, under the cutting action of multiple puncture sub-portions 621, a continuous slit can be formed on the diaphragm 330, avoiding the formation of multiple intermittent slits on the diaphragm 330 and thus preventing the formation of a rupture.

[0049] When the puncture portion 620 includes at least two puncture sub-portions 621, the puncture sub-portion 621 located at the beginning end of the puncture portion 620 and the puncture sub-portion 621 located at the end end of the puncture portion 620 are spaced apart to form the aforementioned gap region 630. In this way, compared to the form in which the puncture portion 620 includes only one puncture sub-portion 621, the width of each puncture sub-portion 621 varies more significantly in the puncture direction of the puncture member 600, that is, the puncture sub-portion 621 is sharper, which improves the smoothness of the diaphragm 330 being punctured.

[0050] It should be understood that, in the embodiments of this application, the puncture portion 620 extends in the circumferential direction of the annular base 610 longer than the gap region 630 extends in the circumferential direction of the annular base 610, thereby preventing the cut portion of the diaphragm 330 from still having a good fit with the opening of the sampling container 300, making it difficult to form a tear for tissue samples to pass through.

[0051] In the embodiments of this application, please refer to Figure 12 The sample collection device also includes a cap 700, which can seal the instrument channel 110 when the biopsy forceps are not inserted, thus preventing some tissue fluid from leaking out of the sample collection device through the instrument channel 110 during the aspiration of tissue fluid from the human body, which could cause the risk of infection of personnel and environmental pollution.

[0052] This application also provides an endoscope; please refer to [link to relevant documentation]. Figure 13 The endoscope includes the aforementioned sample collection device. Exemplarily, the endoscope includes an operating handle and an insertion portion connected to the operating handle. An instrument mouth is provided on the operating handle, and the aforementioned sample collection device is connected to the instrument mouth. Specifically, the instrument channel of the instrument thimble 100 is connected to the instrument mouth of the operating handle.

[0053] The endoscopes used in this application can be bronchoscopes, pyeloscopes, esophagoscopes, gastroscopes, colonoscopes, otoscopes, rhinoscopes, oral endoscopes, laryngoscopes, colposcopes, laparoscopes, arthroscopes, etc. This application does not impose specific limitations on the types of endoscopes.

[0054] It should be noted that, in this document, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes that element. Furthermore, it should be noted that the scope of the methods and apparatuses in the embodiments of this application is not limited to performing functions in the order shown or discussed, but may also include performing functions substantially simultaneously or in the reverse order, depending on the functions involved. For example, the described methods may be performed in a different order than described, and various steps may be added, omitted, or combined. Additionally, features described with reference to certain examples may be combined in other examples.

[0055] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any changes or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in the present invention should be included within the scope of protection of the present invention.

Claims

1. A sample collection device for use in an endoscope, characterized in that, Includes an instrument plug (100), an end cap (200), a sampling container (300), and a sealing plug (400); wherein: The instrument plug (100) is provided with an instrument channel (110) extending along its axial direction and a sample retention channel (120) communicating with the instrument channel (110). The two ends of the sample retention channel (120) are respectively connected to the end cap (200) and the sampling container (300). The sealing plug (400) is located in the sample retention channel (120) and is connected to the end cap (200). The sampling container (300) is configured to move into the sample retention channel (120) when it is pushed, so as to switch from a first state to a second state. In the first state, the sampling container (300) is separated from the sealing plug (400). In the second state, the sampling container (300) is connected to the sealing plug (400), and the connection strength between the sampling container (300) and the sealing plug (400) is greater than the connection strength between the end cap (200) and the sealing plug (400). When a pulling force is applied to the sampling container (300), the connection state between the sealing plug (400) and the end cap (200) is broken, while the connection state between the sealing plug (400) and the sampling container (300) remains.

2. The sample collection device according to claim 1, characterized in that, The instrument plug (100) is provided with a first connecting part (130) on the inner wall of the sample retention channel (120), and the sampling container (300) is provided with a second connecting part (310) on the outer wall. One of the first connecting part (130) and the second connecting part (310) is a snap-fit ​​protrusion and the other is a snap-fit ​​recess. In the first state, the first connecting part (130) and the second connecting part (310) are snap-fitted together.

3. The sample collection device according to claim 2, characterized in that, The inner wall of the sampling container (300) is provided with anti-slip protrusions (320). When the sampling container (300) is in the second state, the anti-slip protrusions (320) abut against the outer wall of the sealing plug (400).

4. The sample collection device according to any one of claims 1 to 3, characterized in that, The sample collection device also includes a movable part (500), which is movably disposed in the sample retention channel (120). The movable part (500) is provided with a sealing plug channel (510) and an instrument perforation (520) penetrating the sealing plug channel (510). In the first state, the movable part (500) abuts against the sampling container (300), and the sealing plug channel (510) is connected to the sampling container (300). At least a portion of the sealing plug (400) is located in the sealing plug channel (510), and the instrument perforation (520) corresponds to the instrument channel (110). During the process of the sampling container (300) switching from the first state to the second state, the sealing plug (400) passes through the sealing plug channel (510) so that at least a portion of the sealing plug (400) is contained within the sampling container (300) to block the opening of the sampling container (300).

5. The sample collection device according to claim 4, characterized in that, The instrument plug (100) is provided with a third connecting part (140) on the inner wall of the sample retention channel (120), and the movable part (500) is provided with a fourth connecting part (530) on the outer wall. One of the third connecting part (140) and the fourth connecting part (530) is a snap-fit ​​protrusion and the other is a snap-fit ​​recess. In the second state, the third connecting part (140) and the fourth connecting part (530) are snap-fitted together.

6. The sample collection device according to claim 4, characterized in that, The sampling container (300) is also provided with a diaphragm (330) at its opening. The movable part (500) is connected with a puncture member (600). When the sampling container (300) switches from the first state to the second state, the puncture member (600) is configured to puncture the diaphragm (330) so that the sampling container (300) is connected to the sample retention channel (120).

7. The sample collection device according to claim 6, characterized in that, The puncture member (600) includes an annular base (610) and a puncture portion (620) connecting the annular base (610). The puncture portion (620) extends circumferentially along the annular base (610), and the ends of the puncture portion (620) are spaced apart to form a gap region (630) so that the punctured diaphragm (330) is connected to the sampling container (300) through its portion corresponding to the gap region (630).

8. The sample collection device according to claim 7, characterized in that, The puncture portion (620) includes at least one puncture sub-portion (621). In the puncture direction of the puncture portion (620), the circumferential width of the puncture sub-portion (621) gradually decreases, so that the end of the puncture portion (620) forms a sharp tip.

9. The sample collection device according to claim 8, characterized in that, When the puncture portion (620) includes at least two puncture sub-portions (621), all the puncture sub-portions (621) are connected end to end, and the puncture portion (620) forms the gap region (630) between the puncture sub-portion (621) at the beginning end and the puncture sub-portion (621) at the end end.

10. An endoscope, characterized in that, The endoscope includes the sample collection device as described in any one of claims 1 to 9.

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