Valve clamping device and valve clamping system

Abstract

This application relates to a valve clamping device and a valve clamping device. The valve clamping device includes a central seat, a locking member, at least two clamping members, and at least two transmission members. The clamping members are arranged around the central seat and are hinged to the central seat via a first rotating shaft. The locking member is disposed within the central seat and is used to lock the first rotating shaft onto the central seat or to release the locking of the first rotating shaft. The transmission members are hinged to the corresponding clamping members via a second rotating shaft. When the locking member releases the locking of the first rotating shaft, the transmission member can slide along the axial direction of the central seat to adjust the opening angle of the corresponding clamping member. The opening angle of each clamping member on this valve clamping device is independently adjustable. The opening angle of each clamping member can be adjusted according to the different valve shapes or the free edge distribution areas of the leaflets of different patients, so that each clamping member can clamp the corresponding cardiac valve leaflet, greatly improving the success rate of the valve clamping device in capturing different lesions in one attempt.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and in particular to a valve clamping device and valve clamping system. Background Technology

[0002] The mitral valve is a vital valve in the heart, located between the left and right atria. Blood is pumped from the left atrium into the left ventricle. When the left ventricle contracts, pumping blood throughout the body, the mitral valve closes to prevent blood from being pumped back into the left atrium. If the mitral valve is diseased and cannot close completely, blood will flow back into the left atrium during left atrium contractions, a condition known as mitral regurgitation. Mitral regurgitation significantly reduces the heart's pumping efficiency, thus placing patients at risk of severe, progressive heart failure.

[0003] Open-heart mitral valve repair and artificial valve replacement are the most effective treatments for mitral regurgitation. However, because the surgery requires cardiopulmonary bypass, it is quite invasive and has a high complication and mortality rate, especially for elderly patients and those with multiple comorbidities.

[0004] In recent years, with the breakthroughs in valvular interventional therapy, mitral regurgitation interventional devices have become one of the key areas of cardiovascular device research and development both domestically and internationally. Mitral valve clipping, as a mainstream interventional treatment, involves inserting an implantable clipping device into the mitral valve appendage through the apex of the heart to clamp and fix the free edges of the anterior and posterior leaflets, ensuring good leaflet closure at end-systole and reducing regurgitation.

[0005] However, in actual use, existing mitral valve clamping devices are prone to valve capture failure due to differences in valve shape or free edge distribution areas of the leaflets among different patients. Summary of the Invention

[0006] Therefore, it is necessary to provide a valve clamping device and valve clamping system to address the problem that existing mitral valve clamping devices are prone to valve capture failure.

[0007] A valve clamping device, the valve clamping device comprising: a central seat, a locking member, at least two clamping members, and at least two transmission members;

[0008] The clamping member is arranged around the center seat and is hinged to the center seat through the first pivot.

[0009] The locking member is disposed in the center seat, and the locking member is used to lock the first rotating shaft on the center seat or to unlock the first rotating shaft;

[0010] The transmission component is hinged to the corresponding clamping component via a second rotating shaft. When the locking component releases the lock on the first rotating shaft, the transmission component can slide along the axial direction of the center seat to adjust the opening and closing angle of the corresponding clamping component.

[0011] In one embodiment, the locking member has a first form and a second form. When the locking member is in the first form, there is a first frictional force between the locking member and the first rotating shaft. When the locking member is in the second form, there is a second frictional force between the locking member and the first rotating shaft, wherein the second frictional force is greater than the first frictional force.

[0012] In one embodiment, the locking element is made of shape memory material, and the original shape of the locking element is the first shape.

[0013] In one embodiment, the locking member is arranged along the axial direction of the center seat, and the deformation direction of the locking member is parallel to the axial direction of the center seat.

[0014] In one embodiment, the locking member has a connecting area and a locking area. The connecting area is connected to the center seat, and the locking area is curved and provided with a locking hole for the first rotating shaft to pass through. The shape of the locking area can be switched between the first shape and the second shape.

[0015] In one embodiment, the locking member includes a first locking arm and a second locking arm, the first locking arm and the second locking arm are connected, and a threading gap is provided between the first locking arm and the second locking arm, wherein the first locking arm and the second locking arm each have the connecting area and the locking area.

[0016] In one embodiment, the locking region of the first locking arm is bent toward the locking region of the second locking arm.

[0017] In one embodiment, a threading notch is provided at the connection between the first locking arm and the second locking arm.

[0018] In one embodiment, the center seat is provided with at least two guide cavities and at least two threading holes; the guide cavities are spaced apart circumferentially along the center seat, and the proximal end of the transmission member is slidably disposed in the corresponding guide cavity; the threading holes are spaced apart circumferentially along the center seat, and the threading holes communicate with the guide cavities in the same circumferential direction.

[0019] In one embodiment, the transmission member includes a first transmission part and a second transmission part that are vertically connected, the first transmission part being hinged to the clamping member, and the proximal end of the second transmission part being movably disposed within the central seat.

[0020] A valve clamping system, the valve clamping system comprising: a delivery device, a first control element, at least two second control elements, at least two third control elements, and a valve clamping device as described in any one of the preceding claims;

[0021] The distal end of the delivery device is connected to the center seat of the valve clamping device. The distal end of the first control member is located outside the delivery device and is connected to the locking member of the valve clamping device. The distal end of the second control member is located outside the delivery device and is connected to the corresponding transmission member on the valve clamping device. The distal end of the third control member is located outside the delivery device and is connected to the corresponding clamping member on the valve clamping device.

[0022] The aforementioned valve clamping device and system are equipped with multiple independent transmission components. Each transmission component can move axially along the central seat to drive the corresponding clamping component to rotate around the central seat. This means the opening angle of each clamping component on the valve clamping device is independently adjustable. This allows for adjustment of the opening angle of each clamping component according to the different valve shapes or the free edge distribution areas of the valve leaflets in different patients, ensuring that each clamping component can clamp the corresponding cardiac valve leaflet. This significantly improves the success rate of the valve clamping device in capturing different lesions on the first attempt, increasing the operability of the valve clamping device. Furthermore, the aforementioned valve clamping device is equipped with a locking component. This locking component can lock the first rotating shaft during the valve clamping device's transport and after it has been inserted to the lesion site, preventing the clamp from opening on its own or under the impact of blood flow, thus ensuring operational safety and the therapeutic effect of the valve clamping device. Alternatively, it can release the lock on the first rotating shaft after the valve clamping device has been transported to the vicinity of the target tissue, allowing the clamp to rotate around the first rotating shaft under the drive of various transmission components until it clamps the corresponding heart valve leaflet, thereby achieving the purpose of repairing the heart valve. It is evident that this valve clamping device can effectively lock or unlock the clamp using only the locking component, which simplifies the structure of the valve clamping device, reduces the number of parts, and lowers the assembly difficulty. Attached Figure Description

[0023] Figure 1 This is a three-dimensional structural diagram of a valve clamping device provided in an embodiment of this application in the open state.

[0024] Figure 2 This is a side view of a valve clamping device provided in an embodiment of this application with the locking member in a second configuration.

[0025] Figure 3 for Figure 2 A cross-sectional view of the provided valve clamping device in the AA direction.

[0026] Figure 4 This is a schematic diagram of the opening process of a valve clamping device provided in an embodiment of this application.

[0027] Figure 5 This is a three-dimensional structural diagram of a locking member provided in an embodiment of this application.

[0028] Figure 6 This is a front view of a locking member provided in an embodiment of this application.

[0029] Figure 7 This is a schematic diagram illustrating the cooperation between a locking member and a second control member according to an embodiment of this application.

[0030] Figure 8 for Figure 3 A magnified view of a portion at point A.

[0031] Figure 9 This is a three-dimensional structural diagram of the center seat provided in an embodiment of this application. Detailed Implementation

[0032] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.

[0033] In the description of this application, it should be understood that if terms such as "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" appear, these terms indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0034] Furthermore, where the terms "first" and "second" appear, these terms are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, where the term "multiple" appears, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0035] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0036] In this application, unless otherwise expressly specified and limited, the use of descriptions such as "above" or "below" the second feature indicates that the first and second features are in direct contact or indirect contact via an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. Similarly, "below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0037] It should be noted that if an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. If so, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used in this application are for illustrative purposes only and do not represent the only possible implementation.

[0038] It should be noted that the terms "distal" and "proximal" in the text are only used to indicate relative positional relationships. The "distal" end of a component refers to the end that enters the patient's body first and / or is farther away from the operator during normal operation, while the "proximal" end refers to the end that enters the patient's body later and / or is closer to the operator.

[0039] See Figures 1 to 3An embodiment of this application provides a valve clamping device 10, which includes: a central seat 100, a locking member 200, a plurality of clamping members 300, and a plurality of transmission members 400. The clamping members 300 are arranged around the central seat 100 and are hinged to the central seat 100 through a first rotating shaft 510. The locking member 200 is disposed inside the central seat 100 and is used to lock the first rotating shaft 510 onto the central seat 100 or to release the locking of the clamping member 300. The transmission member 400 is hinged to the corresponding clamping member 300 through a second rotating shaft 520. When the locking member 200 unlocks the locking of the first rotating shaft 510, the transmission member 400 can slide along the axial direction of the central seat 100 to adjust the opening and closing angle of the corresponding clamping member 300.

[0040] The valve clamping device 10 of this application embodiment can be used as an edge-to-edge repair implant in the field of interventional treatment of structural heart disease. It can reach the designated position through a minimally invasive vascular approach and use the clamping member 300 of the valve clamping device 10 to achieve the repair treatment of the heart leaflet.

[0041] The number of clamping parts 300 can be two, and they can be respectively... Figure 4 The first clamping member 300a and the second clamping member 300b are shown. Both the first clamping member 300a and the second clamping member 300b may include: a large arm 310, a small arm 320, and a capturing arm 330; the large arm 310 is hinged to the center seat 100 via a first rotating shaft 510, the large arm 310 is hinged to the small arm 320 via a third rotating shaft 530, and the small arm 320 is hinged to the transmission member 400 via a second rotating shaft 520; the capturing arm 330 is connected to the center seat 100, and the capturing arm 330 may be made of an elastic material or a shape memory material (e.g., nickel-titanium alloy). The capturing arm 330 is provided with a traction hole 330a for the passage of a fourth control member (e.g., a wire). The capturing arm 330 can be retracted to the periphery of the center seat 100 under the traction of the fourth control member. When the fourth control member is removed, the capturing arm 330 can spring back toward the large arm 310 and cooperate with the large arm 310 to capture the heart valve leaflets. The distal end of the fourth control member can be connected to the capturing arm 330 via a conveying device. It should be noted that the opening angle of the clamping member 300 refers to the angle α between the main arm 310 of the clamping member 300 and the axis of the center seat 100 (see [reference]). Figure 4 ).

[0042] Correspondingly, the number of the aforementioned transmission components 400 is also two, which can be respectively Figure 4 The first transmission member 400a and the second transmission member 400b shown are hinged to the first clamping member 300a to adjust the opening and closing angle of the first clamping member 300a, and the second transmission member 400b is hinged to the second clamping member 300b to adjust the opening and closing angle of the second clamping member 300b.

[0043] The following describes the operation of the valve clamping device 10, taking mitral valve repair as an example. The first clamping member 300a is used to clamp the anterior mitral valve leaflet, and the second clamping member 300b is used to clamp the posterior mitral valve leaflet.

[0044] During operation, firstly, the first clamping member 300a and the second clamping member 300b of the valve clip are closed so that the first clamping member 300a and the second clamping member 300b are in a fully retracted state. Then, the first rotating shaft 510 is locked using the locking member 200, so that the first clamping member 310 and the second clamping member 320 no longer rotate around the central seat 100 and open when the valve clip 10 is transported in the patient's body. Afterward, the valve clip device 10 is transported through the femoral vein using the delivery device. The needle is inserted into the heart, and under the guidance of three-dimensional ultrasound, the large arm 310 of the first clamping member 300a and the large arm 310 of the second clamping member 300b are passed through the middle of the anterior and posterior leaflets of the mitral valve. Then, the locking member 200 is released from locking the first rotating shaft 510, allowing the first clamping member 300a and the second clamping member 300b to rotate on the central seat 100. Then, the first transmission member 400a and the second transmission member 400b are driven to slide along the axial direction of the central seat 100. During the sliding process, a transmission component 400a can drive the large arm 310 of the first clamping component 300a to rotate around the central seat 100 until the large arm 310 of the first clamping component 300a supports the anterior mitral lobe. Similarly, during the sliding process, a second transmission component 400b can drive the large arm 310 of the second clamping component 300b to rotate around the central seat 100 until the large arm 310 of the second clamping component 300b supports the posterior mitral lobe. Afterwards, the first clamping component 300a and the second clamping component 400b are released. The fourth control on the capture arm 330 of the 00b is used to clamp the anterior mitral valve leaflet between the large arm 310 of the first clamping member 300a and the capture arm 330, and the posterior mitral valve leaflet between the large arm 310 of the second clamping member 300b and the capture arm 330; then, the locking member 200 is used to lock the first rotating shaft 510, so that the first clamping member 310 and the second clamping member 320 no longer rotate; finally, the delivery device and the fourth control are removed from the patient's body.

[0045] As can be seen, the valve clamping device 10 described above is equipped with multiple independent transmission components 400. Each transmission component 400 can move axially along the central seat 100 to drive the corresponding clamping component 300 to rotate around the central seat 100. That is, the opening angle of each clamping component 300 on the valve clamping device 10 is independently adjustable. In this way, the opening angle of each clamping component 300 can be adjusted according to the different valve shapes or the free edge distribution areas of the leaflets of different patients, so that each clamping component 300 can clamp the corresponding heart valve leaflet. This can greatly improve the success rate of the valve clamping device 10 in capturing different lesions on the first attempt and increase the operability of the valve clamping device 10. In addition, the valve clamping device 10 is also provided with a locking member 200. The locking member 200 can lock the first rotating shaft 510 during the valve clamping device 10 being transported and after it is delivered to the lesion site and closed, so that the clamping member 300 will not open on its own or under the impact of blood, thereby ensuring the safety of operation and the therapeutic effect of the valve clamping device 10. It can also release the lock on the first rotating shaft 510 after the valve clamping device 10 is transported to the vicinity of the target tissue, so that the clamping member 300 can rotate around the first rotating shaft 510 under the drive of each transmission member 400 until the corresponding heart valve leaflet is clamped, thereby achieving the purpose of repairing the heart valve. It can be seen that the valve clamping device 10 can effectively lock or unlock the clamping member 300 by means of the locking member 200. This simplifies the structure of the valve clamping device 100, reduces the number of parts of the valve clamping device 10, and also reduces the assembly difficulty of the valve clamping device 10.

[0046] In some embodiments of this application, the locking member 200 has a first form and a second form. When the locking member 200 is in the first form, there is a first frictional force between the locking member 200 and the first rotating shaft 510. When the locking member 200 is in the second form, there is a second frictional force between the locking member 200 and the first rotating shaft 510, wherein the second frictional force is greater than the first frictional force. When the locking member 200 is in the second form, the frictional force between the locking member 200 and the first rotating shaft 510 is larger, and the locking member 200 can hold the first rotating shaft 510 tightly. When the locking member 200 is in the first form, the frictional force between the locking member 200 and the first rotating shaft 510 is smaller, and the locking member 200 can release the first rotating shaft 510. It should be noted that the clamping member 300 is rotatable under the drive of the first rotating shaft 510. The locking member 200 can lock or unlock the clamping member 300 by adjusting its own shape to tighten or loosen the first rotating shaft 510. It has the characteristics of simple structure and easy operation.

[0047] Optionally, the locking element 200 can be made of a shape memory material (e.g., nickel-titanium alloy), and its original form is the first form. During the molding process, the locking element 200 made of this material can undergo heat treatment to give it the ability to spring back to its original form after deformation. When the locking element 200 is subjected to external force, it can transform from the first form to the second form; when the external force is removed, the locking element 200 returns to its original form (i.e., the first form).

[0048] Optionally, see Figure 3 The aforementioned locking member 200 is arranged along the axial direction of the center seat 100 (i.e., the locking member 200 can extend along the axial direction of the center seat 100), and the deformation direction of the locking member 200 is parallel to the axial direction of the center seat 100. Compared with the inclined arrangement of the locking member 200, this application can make the locking member 200 deform by the same preset length when it moves a preset length along the axial direction of the center seat 100 under the action of external force. This can effectively lock or unlock the first rotating shaft 510, and provide a more reliable locking stability for the first rotating shaft 510.

[0049] See Figure 5 and Figure 6 In some embodiments of this application, the locking member 200 has a connecting region 200a and a locking region 200b. The connecting region 200a is connected to the center seat 100, and the locking region 200b is curved and has a locking hole 200b1 for the passage of the first rotating shaft 510. The locking region 200b can switch between a first form and a second form. The curved locking region 200b is more easily deformed under the action of external force. It should be noted that when the locking member 200 is in the first form, the locking member 200 can fix the first rotating shaft 510 in the locking hole 200b1 by frictional contact with the first rotating shaft 510; when the locking member 200 is in the second form, the locking hole 200b1 also deforms, so that the locking hole 200b1 no longer has frictional contact with the first rotating shaft 510, thereby releasing the first rotating shaft 510.

[0050] Optionally, the connection area 200a of the locking member 200 can be connected to the center seat 100 by welding, screw connection or other means.

[0051] Further, see Figure 7 The aforementioned locking member 200 includes a first locking arm 210 and a second locking arm 220, which are connected. A threading gap 200c is provided between the first locking arm 210 and the second locking arm 220. Both the first locking arm 210 and the second locking arm 220 have a connecting area 200a and a locking area 200b. See also... Figure 7During operation, first, pass the first control member 20 through the threading gap 200c, then pull the first control member 20 downwards until the locking member 200 changes from the first form to the second form. At this time, the locking holes 200b1 on the first locking arm 210 and the second locking arm 220 also change from the first form to the second form. Figure 6 The circle shown has become Figure 8 The elongated shape shown ensures that the arm of the locking hole 200b1 is tightly fitted against the first rotating shaft 510, thus locking the first rotating shaft 510. When the first control member 20 is released, the locking member 200 moves along the... Figure 7 Resetting the device in the opposite direction to the traction direction, as shown, will restore it to its first state. At this time, the locking hole 200b1 on the locking member 200 will be restored to its original position. Figure 6 As shown, the circular locking hole 200b1 is no longer in close contact with the first rotating shaft 510, thus releasing the lock on the first rotating shaft 510.

[0052] Optionally, see Figure 5 The locking region 200b of the first locking arm 210 and the locking region 200b of the second locking arm 220 are bent towards each other, that is, the locking region 200b of the first locking arm 210 bends toward the locking region 200b of the second locking arm 220, and the locking region 200b of the second locking arm 220 bends toward the locking region 200b of the first locking arm 210. This arrangement reduces the space occupied by the locking member 200, thereby reducing the volume of the valve clamping device 10.

[0053] Optionally, see Figure 6 A wire-threading notch 200d is provided at the connection point between the first locking arm 210 and the second locking arm 220. This notch 200d facilitates the insertion of the first control member 20. Specifically, a wire-threading notch 200d is provided at each end of the connection point between the first locking arm 210 and the second locking arm 220. See, as an example... Figure 5 and Figure 6 The first locking arm 210 and the second locking arm 220 also have a transition region 200e. The transition region 200e of the first locking arm 210 and the transition region 200e of the second locking arm 220 are connected at their proximal ends to connect the first locking arm 210 and the second locking arm 220 into a whole. The notch 200d is provided at the proximal end of the transition region 200e.

[0054] In some embodiments of this application, see Figure 9The center seat 100 is provided with at least two guide cavities 100a, which are spaced apart circumferentially along the center seat 100. The proximal end of the transmission member 400 is slidably disposed in the corresponding guide cavity 100a. The guide cavity 100a guides the sliding of the transmission member 400, facilitating the opening and closing of the clamping member 300. It can be understood that the guide cavities 100a are arranged along the sliding direction of the corresponding transmission member 400, and the number of guide cavities 100a can be the same as the number of transmission members 400, that is, the guide cavity 100a corresponds one-to-one with the transmission member 400.

[0055] Optionally, see Figure 9 The center seat 100 is also provided with a mounting cavity 100c, which extends from the proximal end to the distal end of the center seat 100. The first locking arm 210 and the second locking arm 220 of the locking member 200 can be respectively installed on two opposite cavity walls in the mounting cavity 100c, wherein the two cavity walls are provided with mounting holes 100d for the passage of the first rotating shaft 510, and the guide cavity 100a communicates with the mounting cavity 100c.

[0056] Optionally, see Figure 9 The center seat 100 is also provided with a plurality of threading holes 100b, which are spaced apart along the circumference of the center seat 100 and communicate with the guide cavity 100a in the same circumferential direction. During operation, the conveying device can be connected to the center seat 100 first, and the distal end of the second control element (e.g., the wire) extends from the distal end of the conveying device and enters the guide cavity 100a through the threading hole 100b on the center seat 100 to connect with the corresponding transmission element 400. The transmission element 400 is driven to slide along the center seat 100 by pulling the second control element.

[0057] In some embodiments of this application, see Figure 3 The transmission component 400 includes a first transmission part 410 and a second transmission part 420 vertically connected. The first transmission part 410 is hinged to the clamping member 300, and the proximal end of the second transmission part 420 is axially slidably disposed within the central seat 100. This transmission component 400 has a simple structure. Compared to existing systems where multiple clamping members 300 share a single transmission component 400, the total weight of the valve clamping device 10 of this application is not significantly increased, and it does not increase the burden on the patient's heart.

[0058] Optionally, the second transmission part 420 is provided with an operation hole (not shown in the figure) for the passage of the second control member. The distal end of the second control member can pass through the distal end of the conveying device and enter the center seat 100 to connect with the corresponding second transmission part 420.

[0059] All components of the valve clamping device 10 are made of biocompatible materials to prevent further heart valve lesions after clamping.

[0060] On the other hand, this application embodiment also provides a valve clamping system, which includes: a delivery device, a first control member, at least two second control members, at least two third control members, and a valve clamping device 10 as described in any of the above claims; the distal end of the delivery device is connected to the center seat 100 of the valve clamping device 10, the distal end of the first control member is located outside the delivery device and is connected to the locking member 200 of the valve clamping device 10, the distal end of the second control member is located outside the delivery device and is connected to the corresponding transmission member 400 on the valve clamping device 10, and the distal end of the third control member is located outside the delivery device and is connected to the corresponding clamping member 300 on the valve clamping device 10.

[0061] As an example, the first control element, the second control element, and the third control element mentioned above can all be control lines.

[0062] As an example, the aforementioned delivery device may include a sheath assembly and a handle disposed on the proximal end of the sheath assembly. The proximal ends of the first, second, and third control members are all connected to the handle, and the distal ends of the first, second, and third control members all extend from the sheath assembly. By operating the handle, the first, second, or third control member is pulled, thereby controlling the locking member 200, the transmission member 400, and the clamping member 300 of the valve clamping device 10.

[0063] As an example, the clamping member 300 of the valve clamping device 10 described above may include a large arm 310, a small arm 320, and a capturing arm 330; the large arm 310 is hinged to the center seat 100 via a first pivot 510, the large arm 310 is hinged to the small arm 320 via a third pivot 530, the small arm 320 is hinged to the transmission member 400 via a second pivot 520, and the capturing arm 330 is connected to the center seat 100. The capturing arm 330 may be made of an elastic material or a shape memory material (e.g., nickel-titanium alloy); the distal end of the third control member is connected to the capturing arm 330 on the corresponding clamping member 300.

[0064] The aforementioned valve clamping system includes multiple independent transmission components 400 on the valve clamping device 10. Each transmission component 400 can move axially along the central seat 100 to drive the corresponding clamping component 300 to rotate around the central seat 100. This means the opening angle of each clamping component 300 on the valve clamping device 10 is independently adjustable. This allows for adjustment of the opening angle of each clamping component 300 according to different patient valve shapes or the distribution area of ​​the free edge of the valve leaflets, ensuring that each clamping component 300 can clamp the corresponding cardiac valve leaflet. This significantly improves the success rate of the valve clamping device 10 in capturing different lesions on the first attempt, increasing the overall effectiveness of the valve clamping device 10. Operability; In addition, the valve clamping device 10 is also provided with a locking member 200. The locking member 200 can lock the first rotating shaft 510 during the valve clamping device 10 being transported and after it is delivered to the lesion site and closed, so that the clamping member 300 will not open on its own or under the impact of blood, thereby ensuring the safety of operation and the therapeutic effect of the valve clamping device 10; it can also release the lock on the first rotating shaft 510 after the valve clamping device 10 is transported to the vicinity of the target tissue, so that the clamping member 300 can rotate around the first rotating shaft 510 under the drive of the transmission member 400 until the corresponding heart valve leaflet is clamped, thereby achieving the purpose of repairing the heart valve. It can be seen that the valve clamping device 10 can effectively lock or unlock the clamping member 300 by means of the locking member 200. This simplifies the structure of the valve clamping device 100, reduces the number of parts of the valve clamping device 10, and also reduces the assembly difficulty of the valve clamping device 10.

[0065] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0066] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. A valve clamping device, characterized in that, The valve clamping device includes: a central seat, a locking element, at least two clamping elements, and at least two transmission elements; The clamping member is arranged around the center seat and is hinged to the center seat through the first pivot. The locking member is disposed in the center seat, and the locking member is used to lock the first rotating shaft on the center seat or to unlock the first rotating shaft; The transmission component is hinged to the corresponding clamping component via the second rotating shaft. When the locking component releases the lock on the first rotating shaft, the transmission component can slide along the axial direction of the center seat to adjust the opening and closing angle of the corresponding clamping component. The locking member has a first form and a second form. When the locking member is in the first form, there is a first frictional force between the locking member and the first rotating shaft. When the locking member is in the second form, there is a second frictional force between the locking member and the first rotating shaft, wherein the second frictional force is greater than the first frictional force.

2. The valve clamping device according to claim 1, characterized in that, The locking component is made of shape memory material, and the original shape of the locking component is the first shape.

3. The valve clamping device according to claim 1, characterized in that, The locking member is arranged along the axial direction of the center seat, and the deformation direction of the locking member is parallel to the axial direction of the center seat.

4. The valve clamping device according to claim 1, characterized in that, The locking member has a connecting area and a locking area. The connecting area is connected to the center seat. The locking area is curved and has a locking hole for the first rotating shaft to pass through. The shape of the locking area can be switched between the first shape and the second shape.

5. The valve clamping device according to claim 4, characterized in that, The locking component includes a first locking arm and a second locking arm, the first locking arm and the second locking arm are connected, and a threading gap is provided between the first locking arm and the second locking arm, wherein the first locking arm and the second locking arm each have the connecting area and the locking area.

6. The valve clamping device according to claim 5, characterized in that, The locking region of the first locking arm bends toward the locking region of the second locking arm.

7. The valve clamping device according to claim 5, characterized in that, A notch for threading is provided at the connection point between the first locking arm and the second locking arm.

8. The valve clamping device according to any one of claims 1 to 7, characterized in that, The center seat is provided with at least two guide cavities and at least two threading holes; the guide cavities are spaced apart along the circumference of the center seat, and the proximal end of the transmission member is slidably disposed in the corresponding guide cavity; the threading holes are spaced apart along the circumference of the center seat, and the threading holes communicate with the guide cavities in the same circumference.

9. The valve clamping device according to any one of claims 1 to 7, characterized in that, The transmission component includes a first transmission part and a second transmission part that are vertically connected. The first transmission part is hinged to the clamping member, and the proximal end of the second transmission part is axially slidably disposed within the central seat.

10. A valve clamping system, characterized in that, The valve clamping system includes: a delivery device, a first control element, at least two second control elements, at least two third control elements, and a valve clamping device as described in any one of claims 1 to 9; The distal end of the delivery device is connected to the center seat of the valve clamping device. The distal end of the first control member is located outside the delivery device and is connected to the locking member of the valve clamping device. The distal end of the second control member is located outside the delivery device and is connected to the corresponding transmission member on the valve clamping device. The distal end of the third control member is located outside the delivery device and is connected to the corresponding clamping member on the valve clamping device.

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