Eye detection system, physiological information acquisition device and eye detection method thereof

Abstract

An eye detection system, a physiological information acquisition device and an eye detection method thereof are disclosed. The eye detection physiological information acquisition device includes a housing, a first light plate assembly and a second light plate assembly. The first light plate assembly and the second light plate assembly are disposed in the housing. The first light plate assembly includes a first circuit board, a first light source module and a signal detection module. The signal detection module detects the reflection of the first light source module irradiated on the eye. The second light plate assembly includes a second circuit board, a second light source module, a lens group, a first camera module and a second camera module. The second light source module includes an inner light emitting element and an outer light emitting element. Through the arrangement of the lens group, the light rays of the second light source module are respectively irradiated on the eye to obtain the relative eye information. The camera optical axis of the first camera module defines an angle with the normal line of the upper surface of the second circuit board, so that the stereoscopic image of the eye can be acquired. The camera optical axis of the second camera module is aligned with the second hole, and the fundus image of the eye can be acquired.

Description

Technical Field

[0001] This invention relates to a detection system for the eye, and more particularly to a device for acquiring physiological information and a detection method thereof. Background Technology

[0002] In recent years, non-invasive instruments have become a common method for detecting physiological conditions in the human body. Compared with traditional invasive testing methods, non-invasive instruments are generally faster, more convenient, and safer, reducing waiting time and the inconvenience of complicated testing procedures. For patients, this reduces the risk of infection caused by physical stimulation and instruments entering the body. Although non-invasive physiological testing instruments are not as accurate as traditional biochemical testing methods, they can still provide some reference value and assist in early physiological monitoring.

[0003] Optical measurement is the method used in most non-invasive instruments. It can be applied to various physiological monitoring and medical tests, including blood pressure monitoring, heart rate monitoring, respiration monitoring, brain imaging, and blood oxygenation monitoring. Furthermore, optical measurement is suitable for patients of different ages, body types, and health conditions. It utilizes the properties of light, such as absorption, scattering, and reflection, to measure different parts of the body and obtain different physiological parameters, which is widely used in clinical and home healthcare.

[0004] For example, most smartwatches on the market are equipped with light sources of specific wavelengths to measure physiological conditions such as blood oxygen and heart rate. Users only need to wear the smartwatch on their wrist and use optical technology to monitor pulse oxygen saturation (SpO2), which measures the oxygen saturation in the blood through the absorption of infrared and visible light. Summary of the Invention

[0005] In view of this, the present invention provides a physiological information acquisition device, an eye detection system, and an eye detection method for use in the eye, which uses multi-band light sources and different types of information acquisition modules to detect the eye.

[0006] In one embodiment, the eye physiological information acquisition device includes a housing, a first light plate assembly, and a second light plate assembly. The housing includes an acquisition side and a mounting side, wherein the acquisition side and the mounting side are opposite to each other. The first light plate assembly is disposed in the housing and located near the acquisition side. The first light plate assembly includes a first circuit board, a first light source module, and a signal detection module. The first circuit board has a first hole. The first light source module is located on the first circuit board and surrounds the first hole. The first light source module includes a plurality of first light-emitting elements. The signal detection module is located on the first circuit board and has a plurality of signal detectors corresponding to the plurality of first light-emitting elements. The second light plate assembly is disposed in the housing and located near the mounting side. The second light plate assembly includes a second circuit board, a second light source module, a lens group, a first camera module, and a second camera module. The second circuit board has a second hole, which is aligned with the first hole, and the diameter of the first hole is larger than the diameter of the second hole. The second light source module is located on the second circuit board. The second light source module includes a set of internal light-emitting elements and at least a set of external light-emitting elements. The internal light-emitting elements surround the second hole, and the at least a set of external light-emitting elements are arranged concentrically with respect to the center of the second hole and surround the internal light-emitting elements and the second hole. A lens assembly is disposed within the housing with its optical axis aligned with the center of the second hole. The lens assembly includes a first lens that covers the internal light-emitting element and the second hole. Multiple first camera modules are located around the periphery of the second hole, and the camera optical axis of each first camera module is defined at an angle relative to the normal to the upper surface of the second circuit board. The camera optical axis of the second camera module is aligned with the center of the second hole.

[0007] In one embodiment, the first light source module includes a plurality of first light source groups with different wavelengths, and each first light source group includes a plurality of first light-emitting elements having the same wavelength.

[0008] In one embodiment, each first light-emitting element is used to generate a first light ray to illuminate the sclera of the eye, and a plurality of signal detectors are used to receive a first reflected light ray reflected from the sclera of the eye.

[0009] In one embodiment, an internal light-emitting element is used to generate a second light to illuminate the iris and fundus of the eye, multiple external light-emitting elements are used to generate a third light to illuminate the pupil of the eye, and a first camera module is used to receive a first reflected light from the sclera reflecting the first light, a second reflected light from the iris reflecting the second light, and a third reflected light from the fundus reflecting the third light.

[0010] In one embodiment, the second camera module receives a second reflected light from the fundus of the eye reflecting a second ray.

[0011] In one embodiment, the wavelength of the internal light-emitting element is different from the wavelength of at least one set of external light-emitting elements.

[0012] The present invention further provides an eye detection system comprising a physiological information acquisition device, a processor, a first display, and a second display. Each first light-emitting element of the physiological information acquisition device generates a first light to illuminate the sclera of the eye; an internal light-emitting element generates a second light to illuminate the iris and fundus of the eye; at least one set of external light-emitting elements generates a third light to illuminate the pupil; multiple signal detectors receive first reflected light from the sclera and convert it into physiological signals; a first camera module receives the first reflected light from the sclera, the second reflected light from the iris, and the third reflected light from the fundus and converts them into a three-dimensional signal of the eye surface, an iris signal, and a refractive signal, respectively; and a second camera module receives the second reflected light from the fundus and converts it into a fundus signal. The processor is coupled to the physiological information acquisition device and processes the physiological signals and converts them into physiological values, processes the three-dimensional signals of the eye surface and converts them into a three-dimensional image of the eye surface, processes the refractive signals and converts them into refractive value values, processes the fundus signals and converts them into a fundus image, and receives the iris signal. The first display-coupled processor is used to display physiological values, two-dimensional images of the ocular surface, refractive index values, fundus images, and combinations thereof. The second display-coupled processor is used to display three-dimensional images of the ocular surface.

[0013] This invention also provides an eye detection method, comprising the following steps: receiving a detection command; activating a first light source module or a second light source module according to the detection command, wherein the first light source module generates a first light ray, and the second light source module generates a second light ray and a third light ray. When the first light source module is activated, the following steps are performed: activating a signal detection module or a first camera module according to the detection command; receiving a first reflected light ray reflected from the sclera of the eye; when the signal detection module is activated, converting the first reflected light ray into a physiological signal and converting the physiological signal into a physiological value; when the first camera module is activated, converting the first reflected light ray into a three-dimensional signal of the eye surface and converting the three-dimensional signal of the eye surface into a two-dimensional image and a three-dimensional image of the eye surface; and displaying the physiological value or the two-dimensional image and the three-dimensional image of the eye surface. When the second light source module is activated, the following steps are performed: activating the first or second camera module according to the detection command; when the first camera module is activated, receiving the third reflected light from the fundus of the eye, converting the third reflected light into a refractive signal, converting the refractive signal into a luminance value, and displaying the luminance value; when the second camera module is activated, receiving the second reflected light from the fundus of the eye, converting the second reflected light into a fundus signal, converting the fundus signal into a fundus image, and displaying the fundus image.

[0014] The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments, but this is not intended to limit the present invention. Attached Figure Description

[0015] Figure 1 This is a perspective view of a physiological information acquisition device according to an embodiment.

[0016] Figure 2 This is a perspective view of a physiological information acquisition device according to another embodiment.

[0017] Figure 3 for Figure 1 A schematic diagram illustrating the application of this product to the eye area.

[0018] Figure 4 for Figure 1 A three-dimensional schematic diagram of the first light plate assembly and the second light plate assembly in the embodiment.

[0019] Figure 5A This is a top view of a first light plate assembly according to an embodiment.

[0020] Figure 5B This is a top view of a first light plate assembly according to another embodiment.

[0021] Figure 6A A top view of an example of a second light source module in a second light panel assembly.

[0022] Figure 6B A top view of another exemplary example of the second light source module in the second light panel assembly.

[0023] Figure 7 for Figure 4 A cross-sectional view showing the location marked AA.

[0024] Figure 8 This is a top view of a second light plate assembly according to an embodiment.

[0025] Figure 9 This is a perspective view of a physiological information acquisition device according to yet another embodiment, showing that the physiological information acquisition device includes a rotation module.

[0026] Figure 10 for Figure 9 A three-dimensional schematic diagram of an example of a rotating module.

[0027] Figure 11 This is a block diagram of an eye detection system according to an embodiment.

[0028] Figure 12 This is a flowchart of the detection of physiological values ​​and surface images of the eye according to an embodiment of an eye detection method.

[0029] Figure 13 This is a flowchart illustrating the detection of refractive index values ​​and fundus images according to an embodiment of an eye detection method.

[0030] Figure 14 This is a flowchart of an abnormality marking procedure executed according to an embodiment of an eye detection method.

[0031] Figure 15 This is a flowchart of an iris recognition method according to an embodiment of an eye detection method.

[0032] In the attached figures, the following labels are used:

[0033] 10: Eye Detection System

[0034] 100: Physiological Information Acquisition Device

[0035] 120: Casing

[0036] 122: Harvesting side

[0037] 124: Installation side

[0038] 140: First bare panel assembly

[0039] 142: First circuit board

[0040] 144: First hole

[0041] 146: First Light Source Module

[0042] 148: First Light Source Group

[0043] 150: First light-emitting element

[0044] 152: Signal Detection Module

[0045] 154: Signal Detector

[0046] 160: Second light panel assembly

[0047] 162: Second circuit board

[0048] 163a: Upper surface

[0049] 163b: Lower surface

[0050] 164: Second hole

[0051] 166: Second Light Source Module

[0052] 168: Internal light-emitting element

[0053] 170: External light-emitting element

[0054] 172: Opening

[0055] 174: Lens Group

[0056] 176: First Lens

[0057] 176a: First mirror

[0058] 177: Second Lens

[0059] 177a: Second mirror

[0060] 178: Third Lens

[0061] 178a: Third mirror

[0062] 180: First camera module

[0063] 181: Fixed Column

[0064] 181a: Top veneer

[0065] 181b: Lower veneer

[0066] 182: Second camera module

[0067] 184: Rotation Module

[0068] 185: Gear Shaft

[0069] 186: Storage space

[0070] 187: Gear

[0071] 188: Motor

[0072] 200: Processor

[0073] 210: Receiving element

[0074] 220: Storage element

[0075] 240: Database

[0076] 300: First display

[0077] 350: Second monitor

[0078] 40: Eyes

[0079] 41: Pupil

[0080] 42: Sclera

[0081] 44: Iris

[0082] 46: Fundus of the eye

[0083] 48: Lens

[0084] S100~S366: Steps

[0085] COA: Camera Optical Axis

[0086] Ln: Normal line

[0087] θ cam Angle Detailed Implementation

[0088] refer to Figure 1 and Figure 2 , Figure 1 This is a perspective view of a physiological information acquisition device according to an embodiment. Figure 2 This is a perspective view of a physiological information acquisition device according to another embodiment. The physiological information acquisition device 100 includes a housing 120, a first light plate assembly 140, and a second light plate assembly 160. The physiological information acquisition device 100 can be designed for monocular or binocular use. For monocular use, the housing 120 is cylindrical, with its two ends facing each other, namely the acquisition side 122 and the mounting side 124 of the housing 120. When the user uses the physiological information acquisition device 100, the acquisition side 122 is the side closer to the user's eye.

[0089] refer to Figure 3 and Figure 4 , Figure 3 for Figure 1 An illustration of the application of this embodiment to the eye area. Figure 4 for Figure 1 The embodiment shows a three-dimensional schematic diagram of the first and second light plate assemblies. The first light plate assembly 140 of the physiological information acquisition device 100 is disposed within the housing 120 near the acquisition side 122, and the second light plate assembly 160 is also disposed within the housing 120 but near the mounting side 124. For the physiological information acquisition device 100 to be used by both eyes simultaneously, the housing 120 consists of two parallel cylinders joined together, connected by a cross-nose connection structure. Each cylinder has an acquisition side 122 and a mounting side 124. The first light plate assembly 140 and the second light plate assembly 160 are located near the acquisition side 122 and near the mounting side 124, respectively. When using the physiological information acquisition device 100, the distance between the user's eye surface and the first light plate assembly 140 can be less than one centimeter.

[0090] The first light board assembly 140 includes a first circuit board 142, a first light source module 146, and a signal detection module 152. The first circuit board 142 has a first hole 144, the center of which corresponds to the center of the first circuit board 142. The first light source module 146 is located on the first circuit board 142 and surrounds the first hole 144, and includes a plurality of first light-emitting elements 150.

[0091] The signal detection module 152 is located on the first circuit board 142, and the signal detection module 152 is provided with multiple signal detectors 154 corresponding to multiple first light-emitting elements 150. Here, "corresponding" means that the spectral range that the signal detectors 154 can measure covers the wavelength of the first light-emitting elements 150.

[0092] The second light plate assembly 160 includes a second circuit board 162, a second light source module 166, a lens group 174, a plurality of first camera modules 180, and a second camera module 182. The second circuit board 162 is provided with a second hole 164, which is aligned with a first hole 144 and the diameter of the first hole 144 is larger than the diameter of the second hole 164.

[0093] The second light source module 166 is located on the second circuit board 162. The second light source module 166 includes a set of internal light-emitting elements 168 and at least a set of external light-emitting elements 170. The "set" may include multiple internal light-emitting elements 168 or multiple external light-emitting elements 170. For example, four internal light-emitting elements 168 can form a set of internal light-emitting elements 168, and six external light-emitting elements 170 can form a set of external light-emitting elements 170. The set of internal light-emitting elements 168 surrounds the second hole 164, and the at least one set of external light-emitting elements 170 is arranged concentrically with respect to the second hole 164 and surrounds the aforementioned set of internal light-emitting elements 168 and the second hole 164.

[0094] Lens assembly 174 is disposed in housing 120 and the optical axis of lens assembly 174 is aligned with the center of second aperture 164. Lens assembly 174 includes first lens 176, which covers the aforementioned internal light-emitting element 168 and second aperture 164.

[0095] Multiple first camera modules 180 are respectively located around the second hole 164. In some embodiments, there are two first camera modules 180, which are respectively located on both sides of the second hole 164. Each first camera module 180 has its own camera optical axis (COA), and each camera optical axis COA defines an angle θ with respect to the normal Ln of the upper surface 163a of the second circuit board 162. cam (See also: Figure 7 The camera optical axis COA setting can be achieved by fixing the post 181 below each first camera module 180. Taking a triangular prism shape as an example (see reference). Figure 4 One side of the triangular prism serves as the upper surface 181a of the fixed post 181, and the other side serves as the lower surface 181b of the fixed post 181. The angle and included angle θ formed between the upper surface 181a and the lower surface 181b are... camWith the same angle, the upper surface 181a fixes the first camera module 180, and the lower surface 181b is attached to the upper surface 163a of the second circuit board 162, so as to achieve the angle θ defined by the normal Ln of the camera optical axis COA relative to the upper surface 163a. cam In some embodiments, the included angle θ cam The angle is 20 degrees. The camera optical axis of the second camera module 182 is aligned with the center of the second hole 164.

[0096] In some embodiments, the diameter of the first hole 144 is 30 mm, such that when the first light source module 146 surrounds the first hole 144, the diameter of the circle formed by the first light source module 146 is larger than the diameter of the pupil 41 of a typical eye 40. When the diameter of the second hole 164 is smaller than the diameter of the first hole 144, the light generated by the second light source module 166 can pass through the first hole 144 without being blocked by the first circuit board 142. Furthermore, the distance between the second circuit board 162 and the first circuit board 142 is 8 cm, which is matched with the angle θ defined by the camera optical axis of the first camera module 180 relative to the normal Ln of the upper surface 163a of the second circuit board 162. cam When the angle is 20 degrees, the imaging light entering the first camera module 180 can also pass through the first hole 144 without being blocked by the first circuit board 142.

[0097] refer to Figure 5A , Figure 5A This is a top view of an exemplary example of a first light panel assembly. In some embodiments, the first light source module 146 includes a plurality of first light-emitting elements 150 that generate first light rays having the same wavelength.

[0098] In other embodiments, the first light source module 146 includes a plurality of first light source groups 148, and each first light source group 148 includes a plurality of first light-emitting elements 150. The first light emitted by each first light source group 148 has a different wavelength, while the first light emitted by the first light-emitting elements 150 within the first light source group 148 has the same wavelength.

[0099] The wavelength of the first light can be between visible light and infrared light. Taking the first light source module 146 as including multiple first light source groups 148, and the first light-emitting elements 150 in each first light source group 148 producing the same wavelength of the first light, in some embodiments, the wavelengths of the first light produced by the multiple first light source groups 148 can be 460 nm (visible light), 660 nm (visible light), 940 nm (infrared light), 1100 nm (infrared light), 1350 nm (infrared light) and other wavelengths, and are arranged cyclically in the order of a 460 nm first light-emitting element 150, a 660 nm first light-emitting element 150, a 940 nm first light-emitting element 150, an 1100 nm first light-emitting element 150 and a 1350 nm first light-emitting element 150.

[0100] In some other embodiments, the first light source module 146 includes a plurality of first light source groups 148, each of which includes a plurality of first light-emitting elements 150 capable of generating first light rays of different wavelengths. For example, a first light source group 148 includes five first light-emitting elements 150, the wavelengths of the first light rays generated by the five first light-emitting elements 150 being 460 nm, 660 nm, 940 nm, 1100 nm, and 1350 nm, respectively. The first light source groups 148 are adjacent to each other and surround the first aperture 144 to form the first light source module 146.

[0101] Different wavelengths of the first light rays correspond to different physiological substances. For example, a 460 nm first light ray corresponds to bilirubin measurement, a 660 nm first light ray corresponds to blood oxygen saturation measurement, a 940 nm first light ray corresponds to total hemoglobin measurement, an 1100 nm first light ray corresponds to cholesterol measurement, and a 1350 nm first light ray corresponds to glucose measurement. These first light rays illuminate the sclera 42 of the eye 40, and the first reflected light from the sclera 42 is received by the signal detector 154. The signal detector 154 converts the received light signal into an electrical signal and transmits it to the processor 200 for calculation (described in detail later) to obtain information about the aforementioned physiological substances.

[0102] In this embodiment, the detection ranges of the multiple signal detectors 154 of the signal detection module 152 can be divided into two groups corresponding to the wavelength of the first light generated by the first light source group 148. One group of signal detectors 154 covers the visible light range, while the other group covers the infrared light range. The signal detectors 154 with different detection ranges are arranged alternately and surround the periphery of the first light source module 146.

[0103] refer to Figure 5B , Figure 5BThis is a top view of another exemplary example of the first light panel assembly. In other embodiments, a plurality of signal detectors 154 and a plurality of first light-emitting elements 150 are arranged in a circle, with the signal detectors 154 and the first light-emitting elements 150 arranged alternately.

[0104] refer to Figure 6A , Figure 6A This is a top view of an example of a second light source module in a second light panel assembly. At least one set of external light-emitting elements 170 can be three sets. As previously mentioned, a "set" can contain multiple internal light-emitting elements 168 or multiple external light-emitting elements 170. The number of internal light-emitting elements 168 contained in a set of internal light-emitting elements 168 can be the same as or different from the number of external light-emitting elements 170 contained in a set of external light-emitting elements 170, and can be adjusted as needed.

[0105] Multiple internal light-emitting elements 168 and multiple external light-emitting elements 170 are evenly distributed at various angles of the second hole 164. Taking the multiple internal light-emitting elements 168 in a group of internal light-emitting elements 168 distributed in four directions of the second hole 164, and the multiple external light-emitting elements 170 in a group of external light-emitting elements 170 distributed in six directions of the second hole 164 as examples, the four directions can be located at 0 degrees, 90 degrees, 180 degrees and 270 degrees of the second hole 164, respectively, and the six directions can be located at 0 degrees, 60 degrees, 120 degrees, 180 degrees, 240 degrees and 300 degrees of the second hole 164, respectively.

[0106] Taking a group of internal light-emitting elements 168 with one element 168 in each of the four positions as an example, the number of internal light-emitting elements 168 in a group is four. Taking a group of external light-emitting elements 170 with one element 170 in each of the six positions as an example, the number of external light-emitting elements 170 in a group is six. However, when three groups of external light-emitting elements 170 are arranged concentrically around the second hole 164, the total number of external light-emitting elements 170 is eighteen (e.g., ...). Figure 6A (As shown).

[0107] refer to Figure 6B , Figure 6B This is a top view of another exemplary example of the second light source module in the second light panel assembly. In some embodiments, if a group of external light-emitting elements 170 is arranged with two external light-emitting elements 170 in each of six positions (e.g., side by side), then the number of external light-emitting elements 170 included in a group of external light-emitting elements 170 is twelve, and if three groups of external light-emitting elements 170 are arranged in concentric circles around the second hole 164, the total number of external light-emitting elements 170 in the three groups is thirty-six.

[0108] In some embodiments, the internal light-emitting element 168 generates a second light ray, and the external light-emitting element 170 generates a third light ray, the wavelength of which differs from that of the third light ray. The wavelengths of the second and third light rays generated by the internal light-emitting element 168 and the external light-emitting element 170 can be within the near-infrared light wavelength range, wherein the wavelength of the second light ray is a longer wavelength in the near-infrared light band, for example, 940 nanometers, and the wavelength of the third light ray is a shorter wavelength in the near-infrared light band, for example, 810 nanometers. The fact that the second and third light rays are near-infrared light avoids discomfort to the user when light enters the pupil 41, or affects the measurement results due to the user's use of mydriatic agents. Furthermore, the difference in wavelength between the second and third light rays allows the physiological information acquisition device 100 to acquire different information from the eye 40 during use.

[0109] In some embodiments, when the internal light-emitting element 168 and the external light-emitting element 170 generate second and third light rays to illuminate the eye 40, the multiple internal light-emitting elements 168 and the multiple external light-emitting elements 170 within a group are lit sequentially. Taking four internal light-emitting elements 168 in a group located at the four positions of the second hole 164 as an example, the lighting order can be the internal light-emitting element 168 located at 0 degrees, the internal light-emitting element 168 located at 90 degrees, the internal light-emitting element 168 located at 180 degrees, and finally the internal light-emitting element 168 located at 270 degrees.

[0110] When one of the internal light-emitting elements 168 or one of the external light-emitting elements 170 is lit, the remaining internal light-emitting elements 168 or external light-emitting elements 170 will be turned off. If multiple sets of external light-emitting elements 170 are arranged concentrically from the second hole 164, the order in which the multiple external light-emitting elements 170 are lit is as follows: the innermost set of external light-emitting elements 170 is lit first, and after all the multiple external light-emitting elements 170 in the innermost set are lit once, the other set of external light-emitting elements 170 around the innermost set is lit in sequence, and so on until all external light-emitting elements 170 are lit in sequence.

[0111] The second light emitted by the multiple internal light-emitting elements 168 after being lit can illuminate different positions of the iris 44 and the fundus 46 of the user's eye 40. The third light emitted by the multiple external light-emitting elements 170 after being lit can illuminate the pupil 41 of the user's eye 40, and pass through the lens 48 of the eye 40 from the pupil 41 to the fundus 46.

[0112] refer to Figure 7 , Figure 7 for Figure 4The cross-sectional view is marked with AA. When the second light shines on the iris 44 and fundus 46 of the user's eye 40, it can pass through the first lens 176 of the lens group 174. The first lens 176 covers the internal light-emitting element 168, so the second light can be focused outside the physiological information capturing device 100 through the first lens 176. Specifically, when the user uses the physiological information capturing device 100, part of the second light generated by the internal light-emitting element 168 is focused on the anterior edge of the lens 48 of the user's eye 40 through the first lens 176, and then diverged to the fundus 46 through the lens 48. At the same time, the first lens 176 also makes the second light shine on the iris 44 of the user. Therefore, it is better for the first mirror surface 176a of the first lens 176 facing the capturing side 122 to be a concave lens, but it is not limited to this.

[0113] In some embodiments, the lens group 174 may include a second lens 177 and a third lens 178 in addition to the first lens 176. The second mirror surface 177a and the third mirror surface 178a in the second lens 177 and the third lens 178 are convex lenses, used to allow the second reflected light of the second light rays reflected from the back of the eye 46 of the eye 40 to enter the second camera module 182.

[0114] Furthermore, as mentioned above, the camera optical axis of the first camera module 180 is defined with an angle θ relative to the normal Ln of the upper surface 163a of the second circuit board 162. cam This allows the imaging light entering the first camera module 180 to pass through the first hole 144 without being blocked by the first circuit board 142. Here, "imaging light" can refer to the first reflected light reflecting the first ray from the sclera 42, the second reflected light reflecting the second ray from the iris 44, and the third reflected light reflecting the third ray from the fundus 46.

[0115] When multiple internal light-emitting elements 168 and multiple external light-emitting elements 170 are lit sequentially, the first camera module 180 receives the second reflected light of the second light or the third reflected light of the third light after each lighting. In this way, the third reflected light generated when each third light shines on different positions of the eye 40 can be obtained.

[0116] In some embodiments, the first camera module 180 is located on the upper surface 163a of the second circuit board 162, while in other embodiments, the first camera module 180 is located below the second circuit board 162, with its lens facing the lower surface 163b of the second circuit board 162.

[0117] refer to Figures 8 to 10 , Figure 8 This is a top view of a second light plate assembly according to an embodiment. Figure 9This is a perspective view of a physiological information acquisition device according to another embodiment, showing that the physiological information acquisition device includes a rotation module. Figure 10 for Figure 9 A three-dimensional schematic diagram of an example of a rotating module.

[0118] In some embodiments, to allow the third light generated by the second light source module 166 to illuminate more areas of the fundus 46, the physiological information acquisition device 100 includes a rotation module 184. The rotation module 184 is located within the housing 120 and on the mounting side 124. The second circuit board 162 has openings 172 corresponding to the number of first camera modules 180, and the openings 172 are located between the inner light-emitting element 168 and the outer light-emitting element 170. The openings 172 may be arc-shaped. The rotation module 184 causes the second circuit board 162 to rotate relative to the center of the second hole 164, and the path of its rotation corresponds to the arc length of the opening 172. The first camera module 180 can receive the first reflected light, the second reflected light, and the third reflected light through the opening 172.

[0119] By rotating the second circuit board 162 via the rotating module 184, the position of the third light emitted by each external light-emitting element 170 illuminating the bottom of the eye 46 will change accordingly, so that compared with the fixed second circuit board 162, the first camera module 180 can receive more third reflected light reflected from different positions of the bottom of the eye 46.

[0120] The rotation module 184 can be implemented using a gear shaft 185, a gear 187, and a motor 188. The gear shaft 185 has a receiving space 186, within which the second camera module 182 can be located without being affected by the rotation module 184. The lower surface 163b of the second circuit board 162 is fixed to the gear shaft 185. The rotation of the second circuit board 162 is achieved by the rotation module 184 through the rotation of the gear shaft 185 via the rotation of the gear 187 by the motor 188.

[0121] In some embodiments, the first camera module 180 is a multispectral camera. Two multispectral cameras are used to take pictures from both sides of the eye 40. The captured images can be transmitted to the processor 200 for image processing, restored into a stereoscopic image, and displayed on the second display 350 to present the stereoscopic image of the eye 40 so that the user can intuitively understand the distribution of physiological substances from the stereoscopic image.

[0122] In some embodiments, the second camera module 182 is a liquid lens camera, which includes a liquid lens and an actuation module. The actuation module can change the shape of the liquid lens to achieve fast focusing. In addition, the actuation module can also cause the liquid lens to deform and change the optical axis of the liquid lens, thereby increasing the image capture range of the second camera module 182, and thus being applied to the shooting of the fundus 46.

[0123] In some embodiments, a strap can be connected to the outside of the housing 120 to form a head-mounted device for physiological information acquisition 100, which not only facilitates user use but also achieves stable data acquisition. In other embodiments, a desktop fixing device can be connected to the outside of the housing 120 to form a desktop detection device for physiological information acquisition 100.

[0124] refer to Figure 11 , Figure 11 This is a block diagram of an eye detection system according to an embodiment. The eye detection system 10 includes the aforementioned physiological information acquisition device 100, and also includes a processor 200, a first display 300, and a second display 350. The processor 200 is coupled to the physiological information acquisition device 100, and the first display 300 and the second display 350 are respectively coupled to the processor 200.

[0125] The housing 120 of the physiological information acquisition device 100 may have a connection cable slot, through which the processor 200 is connected to the first circuit board 142 and the second circuit board 162 of the physiological information acquisition device 100 via a connection cable. The format of the connection cable slot is not limited. Alternatively, a wireless communication module may be provided in the physiological information acquisition device 100 to connect the physiological information acquisition device 100 to the processor 200 via wireless communication.

[0126] In some embodiments, the eye detection system 10 includes a receiving element 210. After a user inputs a command through the receiving element 210, the receiving element 210 generates a detection command. The user-input command may be to detect different parts of the aforementioned eye 40. After receiving the detection command, the processor 200 activates the physiological information acquisition device 100 according to the content of the detection command. Through the physiological information acquisition device 100 and the processor 200, the user can obtain the following information when using the eye detection system 10: 1) multiple physiological values ​​of physiological substances in the eye 40; 2) two-dimensional or three-dimensional images of the surface of the eye 40; 3) the refractive value of the eye 40; and 4) fundus images of the fundus 46.

[0127] The first display 300 may have a user interface, through which the user inputs commands, and the receiving element 210 receives the commands and generates detection commands. The user interface may have options for detecting specific body parts or for detecting specific items (such as physiological substances, refractive index, etc.).

[0128] refer to Figure 12 , Figure 12This is a flowchart illustrating the detection of physiological values ​​and an image of the eye surface according to an embodiment of an eye detection method. When a user desires to obtain multiple physiological values ​​of physiological substances in the eye 40, the processor 200 receives a detection command related to the detection of physiological substances (step S100) and activates the first light source module 146 according to the detection command (step S200). Each first light-emitting element 150 of the first light source module 146 generates first light to illuminate the sclera 42 of the eye 40. The processor 200 activates the signal detection module 152 according to the detection command (step S210). The signal detector 154 of the signal detection module 152 receives the first reflected light from the first light reflected from the sclera 42 (step S212) and converts the first reflected light into a physiological signal (step S214). The signal detector 154 receives the first reflected light to obtain the optical signal of the first reflected light, and the signal detector 154 can convert the optical signal into an electrical signal (i.e., a physiological signal), thereby enabling the processor 200 to process the electrical signal.

[0129] The first light source module 146 and the signal detection module 152 can illuminate for two seconds and receive for two seconds, so as to illuminate the eye 40 with low power in a short time and immediately detect the photoelectric signal change of the first light.

[0130] After receiving the physiological signal transmitted from the signal detector 154, the processor 200 converts the physiological signal into a physiological value (step S216). The physiological value varies depending on the first light emitted by the first light-emitting element 150. Taking a wavelength of 460 nanometers as an example, the physiological value converted by the processor 200 is a bilirubin value. If first light of different wavelengths is emitted simultaneously, physiological values ​​of different physiological substances can be obtained simultaneously. The physiological value is then transmitted to the first display 300 and displayed by the first display 300 (step S218).

[0131] Reference Figure 12 When a user desires to obtain a two-dimensional or three-dimensional image of the surface of the eye 40, the processor 200 receives a detection command for detecting the ocular surface image (step S100) and activates the first light source module 146 according to the detection command (step S200). Each of the first light-emitting elements 150 of the first light source module 146 generates first light to illuminate the sclera 42 of the eye 40. Unlike the detection of physiological values, the processor 200 activates the first camera module 180 according to the detection command (step S220). The first camera module 180 receives the first reflected light from the first light reflected from the sclera 42 (step S222) and converts the first reflected light into a three-dimensional signal of the ocular surface (step S224).

[0132] After receiving the three-dimensional signal of the eye surface transmitted from the first camera module 180, the processor 200 converts it into a two-dimensional image and a three-dimensional image of the eye surface (step S226). The processor 200 transmits the two-dimensional image of the eye surface to the first display 300 for display, and transmits the three-dimensional image of the eye surface to the second display 350 for display (step S228). In some embodiments, the second display 350 is a 3D glasses-free display, so the two-dimensional and three-dimensional images of the eye surface can be viewed simultaneously. In some embodiments, only the two-dimensional image of the eye surface may be displayed on the first display 300 or only the three-dimensional image of the eye surface may be displayed on the second display 350.

[0133] refer to Figure 13 , Figure 13 This is a flowchart of an eye detection method according to an embodiment, which detects the refractive value and fundus image. When the user wants to obtain the refractive value of the eye 40, the processor 200 receives a detection command for detecting the refractive value of the eyeball (step S100), and activates the second light source module 166 according to the detection command (step S300). The external light-emitting elements 170 at different positions of the second hole 164 are lit one by one in sequence to generate a third light that illuminates the pupil 41 of the eye 40.

[0134] To obtain the value of the refractive index, the processor 200 starts the first camera module 180 according to the detection command (step S320). After each external light-emitting element 170 generates the third light, the first camera module 180 receives the third reflected light reflected from the third light reflected from the fundus 46 once (step S322), and converts the multiple third reflected lights into refractive signals one by one (step S324), so that multiple refractive signals can be obtained in the end.

[0135] After receiving multiple refractive signals transmitted from the first camera module 180, the processor 200 converts them into diopter values ​​through image processing (step S326). The processor 200 transmits the diopter values ​​to the first display 300 for display (step S328). The diopter values ​​can provide the near and far vision diopters of the user's eye 40.

[0136] Reference Figure 13 When the user desires to obtain a fundus image of the fundus 46, the processor 200 receives a detection command for detecting the fundus image (step S100) and activates the second light source module 166 according to the detection command (step S300). Similar to the detection of diopter values, the second light source module 166 also activates the internal light-emitting element 168 to generate a second light when it is activated. At this time, the second light is able to illuminate the fundus 46 through the lens group 174.

[0137] The difference from detecting the diopter value is that, at this time, the processor 200 activates the second camera module 182 according to the detection command (step S340). The second camera module 182 receives the second reflected light from the second light reflected from the fundus 46 (step S342) and converts the second reflected light into a fundus signal (step S344). Since the optical axis angle of the second camera module can be adjusted by the actuation module, multiple fundus signals can be obtained before and after adjusting the optical axis angle.

[0138] The processor 200 receives fundus signals transmitted from the second camera module 182. The fundus signals may be composed of a single fundus signal or multiple fundus signals. Through image processing by the processor 200, the signals are converted into fundus images (step S346) and transmitted to the first display 300 for display (step S348).

[0139] refer to Figure 14 , Figure 14 This is a flowchart illustrating the execution of an anomaly marking procedure in an eye detection method according to one embodiment. In some embodiments, the processor 200 executes an anomaly marking procedure on the fundus signal (step S350), enabling the first display 300 to selectively display anomaly markings on the fundus image. Here, "selective" means that when the processor 200 determines that the fundus signal contains a signal consistent with an abnormal condition (e.g., a signal with lesion characteristics), the first display 300 displays the area on the fundus image with an anomaly marking (step S354); if the processor 200 does not identify an abnormal condition, no anomaly markings are displayed in the visual image, and only the fundus image is displayed on the first display 300 (step S352). The anomaly marking in the fundus image is not limited to one; multiple anomaly markings can be displayed simultaneously. The anomaly marking procedure can be performed using an AI neural network, which is based on data within the database 240 and deep learning.

[0140] In some embodiments, the eye detection system 10 includes a storage element 220 coupled to a processor 200, which stores physiological signals, three-dimensional signals of the ocular surface, refractive signals, or fundus signals received by the processor 200. The storage element 220 may be coupled to the processor 200 in a wired or wireless manner.

[0141] Reference Figure 11 and reference Figure 15 , Figure 15This is a flowchart of iris recognition according to an embodiment of an eye detection method. In some embodiments, the eye detection system 10 includes a database 240 that stores multiple iris data. After the processor 200 receives a detection command (step S100), it can first perform iris recognition on the user and then display information corresponding to the user, such as the user's identity data or detection records. Specifically, when the processor 200 executes steps S100 to S354, the second light source module 166 can be activated between any of the steps (step S300).

[0142] As mentioned above, when the second light source module 166 is started, it will simultaneously activate the internal light-emitting element 168 and the external light-emitting element 170 to generate a second light and a third light. The second light can illuminate the iris portion 44 of the eye 40. After the first camera module 180 is activated (step S360) and receives the second reflected light reflected from the iris portion 44 (step S362), it can convert the second reflected light into an iris signal (step S364).

[0143] The iris signal is compared with multiple iris data in the database 240 (step S366) to identify which of the multiple iris data corresponds to the iris signal, and the information carried by the corresponding iris signal in the multiple iris data is output on the first display 300. The information is the aforementioned user's identity data or detection record.

[0144] In some embodiments, the database 240 is stored within the storage element 220 or in an external device. If in an external device, the database 240 can be connected to the processor 200 and the storage element 220 via wired or wireless means. When using the eye detection system 10, the user can first open a folder dedicated to that user in the storage element 220. After iris recognition, the user's iris data information is imported from the database 240. Subsequently, the user's physiological substances, ocular surface images, refractive power, or fundus images are detected, and the detected physiological signals, three-dimensional ocular surface signals, refractive signals, or fundus signals are stored in the user's folder.

[0145] In some embodiments, the first display 300 may be a general non-touchscreen or a touchscreen, and the user may select the test items on the user interface by means of the touchscreen or by means of a mouse, keyboard or other devices.

[0146] In some embodiments, the first display 300, processor 200, receiving element 210, storage element 220, and database 240 can be integrated into an electronic device, wherein the processor 200 is a processor built into the electronic device, the storage element 220 is the built-in or external memory of the electronic device, and the first display 300 is a screen that the electronic device has or is connected to. The electronic device may be a desktop computer, a laptop computer, a tablet computer, etc.

[0147] In some embodiments, the processor 200 may be, but is not limited to, a central processing unit (CPU), a system on chip (SOC), a general-purpose or special-purpose microprocessor, a digital signal processor (DSP), a programmable controller, an application-specific integrated circuit (ASIC), a programmable logic device (PLD), other similar processing devices, or a combination of these devices.

[0148] In some embodiments, the physiological information acquisition device 100 may be powered by an adapter, a battery, or by drawing power from an external source via a transmission line. If the battery supplying power to the device is a rechargeable battery, it may also be charged via an adapter or a transmission line.

[0149] In summary, after the physiological information acquisition device 100 is integrated into the eye detection system 10, the eye 40 is irradiated with light of multiple wavelengths (first light, second light, third light), and the reflected light of each wavelength is acquired by the signal detection module 152, the first camera module 180 or the second camera module 182, and the data of the processor 20 is processed to obtain the data of various physiological or biochemical detections of the eye 40.

[0150] Of course, the present invention may have other various embodiments. Without departing from the spirit and essence of the present invention, those skilled in the art can make various corresponding changes and modifications according to the present invention, but these corresponding changes and modifications should all fall within the protection scope of the claims of the present invention.

Claims

1. A physiological information acquisition device, characterized in that, Include: A housing comprising a retrieving side and a mounting side, wherein the retrieving side and the mounting side are opposite to each other; A first light plate assembly is disposed within the housing and located near the acquisition side. The first light plate assembly includes: The first circuit board has a first hole; A first light source module is located on the first circuit board and surrounds the first hole, and the first light source module includes a plurality of first light-emitting elements; and A signal detection module, located on the first circuit board, is provided with multiple signal detectors corresponding to the plurality of first light-emitting elements; and A second light plate assembly is disposed within the housing and located near the mounting side. The second light plate assembly includes: The second circuit board has a second hole, which is aligned with the first hole and the diameter of the first hole is larger than the diameter of the second hole. The second light source module is located on the second circuit board. The second light source module includes a set of internal light-emitting elements and at least a set of external light-emitting elements. The set of internal light-emitting elements surrounds the second hole, and the at least a set of external light-emitting elements are arranged in concentric circles with respect to the center of the second hole and surround the set of internal light-emitting elements and the second hole. A lens group is disposed in the housing and its lens optical axis is aligned with the center of the second hole. The lens group includes a first lens that covers the light-emitting element and the second hole. Multiple first camera modules are respectively located around the second hole, and the camera optical axis of each first camera module is defined by an angle relative to the normal of the upper surface of the second circuit board; and The second camera module has its camera optical axis aligned with the center of the second hole; The first light source module and the second light source module are light sources of different wavelengths; The signal detection module, the first camera module, or the second camera module captures reflected light in various bands to obtain data for multiple physiological detections.

2. The physiological information acquisition device according to claim 1, characterized in that, The first light source module includes multiple first light source groups with different wavelengths, and each first light source group includes multiple first light-emitting elements with the same wavelength.

3. The physiological information acquisition device according to claim 1, characterized in that, Each of the first light-emitting elements is used to generate a first light ray to illuminate the sclera of the eye, and the plurality of signal detectors are used to receive a first reflected light from the sclera of the eye reflecting the first light ray.

4. The physiological information acquisition device according to claim 3, characterized in that, The set of internal light-emitting elements is used to generate a second light to illuminate the iris and fundus of the eye, and the at least one set of external light-emitting elements is used to generate a third light to illuminate the pupil of the eye. The first camera module is used to receive the first reflected light from the sclera of the eye reflecting the first light, the second reflected light from the iris of the eye reflecting the second light, and the third reflected light from the fundus of the eye reflecting the third light.

5. The physiological information acquisition device according to claim 4, characterized in that, The second camera module receives the second reflected light from the back of the eye, which reflects the second light.

6. The physiological information acquisition device according to claim 1, characterized in that, The wavelength of the set of internal light-emitting elements is different from the wavelength of the at least one set of external light-emitting elements.

7. The physiological information acquisition device according to claim 1, characterized in that, The circuit board includes a rotation module, and the second circuit board has multiple openings located between the group of internal light-emitting elements and the at least one group of external light-emitting elements. The rotation module is used to rotate the second circuit board relative to the center of the second hole.

8. The physiological information acquisition device according to claim 1, characterized in that, The first camera module is a multispectral camera.

9. The physiological information acquisition device according to claim 1, characterized in that, The second camera module includes a liquid lens and an actuation module, wherein the actuation module causes the liquid lens to deform, thereby changing the focal length of the liquid lens.

10. The physiological information acquisition device according to claim 9, characterized in that, The actuation module is further used to actuate the deformation of the liquid lens to change the optical axis of the liquid lens.

11. An eye detection system, characterized in that, Include: The physiological information acquisition device as described in any one of claims 1 to 10, wherein: Each of the first light-emitting elements is used to generate a first light to illuminate the sclera of the eye; The set of internal light-emitting elements is used to generate a second light to illuminate the iris and fundus of one eye; The at least one set of external light-emitting elements is used to generate a third light ray to illuminate the pupil of the eye; The plurality of signal detectors are used to receive the first reflected light from the sclera reflecting the first light and convert it into a physiological signal; The first camera module is used to receive the first reflected light reflected from the sclera, the second reflected light reflected from the iris, and the third reflected light reflected from the fundus, and converts them into three-dimensional signals of the eye surface, iris signals, and refractive signals, respectively; and The second camera module receives the second reflected light from the fundus of the eye and converts it into a fundus signal; The processor, coupled to the physiological information acquisition device, is used to process the physiological signals and convert them into physiological values, process the three-dimensional signals of the ocular surface and convert them into three-dimensional images and two-dimensional images of the ocular surface, process the refractive signals and convert them into refractive brightness values, process the fundus signals and convert them into fundus images, and receive the iris signals. A first display, coupled to the processor, is used to display the physiological values, the two-dimensional image of the ocular surface, the refractive index values, the fundus image, and a group consisting of combinations thereof; and A second display, coupled to the processor, is used to display the three-dimensional image of the eye surface.

12. The eye detection system according to claim 11, characterized in that, It includes a storage element coupled to the processor for storing the physiological signals, the three-dimensional signals of the ocular surface, the iris signals, the refractive signals, and the fundus signals.

13. The eye detection system according to claim 11, characterized in that, The processor includes a database and is used to compare the iris signal with iris data in the database.

14. The eye detection system according to claim 11, characterized in that, The processor selectively activates either the first light source module or the second light source module according to the detection command.

15. An eye detection method, applied to the eye detection system according to any one of claims 11-14, characterized in that, Include: Receive detection command; The first light source module or the second light source module is activated according to the detection command. The first light source module is used to generate a first light ray, and the second light source module is used to generate a second light ray and a third light ray. When the first light source module is activated, the following steps are performed: The signal detection module or the first camera module is activated according to the detection command; Receive the first reflected light from the sclera of the eye reflecting the first light ray; When the signal detection module is activated, the first reflected light is converted into a physiological signal and the physiological signal is converted into a physiological value; when the first camera module is activated, the first reflected light is converted into a three-dimensional signal of the eye surface and the three-dimensional signal of the eye surface is converted into a two-dimensional image and a three-dimensional image of the eye surface; and Display the physiological values ​​or the two-dimensional image and the three-dimensional image of the eye surface; and When the second light source module is activated, the following steps are performed: The first camera module or the second camera module is activated according to the detection command; When the first camera module is activated, it receives the third reflected light from the fundus of the eye, which is reflected by the third ray; converts the third reflected light into a refractive signal; converts the refractive signal into a luminance value; and displays the luminance value. When the second camera module is activated, it receives the second reflected light from the fundus of the eye reflecting the second light, converts the second reflected light into a fundus signal, converts the fundus signal into a fundus image, and displays the fundus image.

16. The eye detection method according to claim 15, characterized in that, Include: The second light source module is activated according to the detection command; Start the first camera module; Receive the second reflected light from the eye reflecting the second light ray; and The second reflected light is converted into an iris signal, and the iris signal is compared with the iris data in the database.

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