Animal respiratory ventilation device and intelligent triggering method thereof

Abstract

The application relates to a respiratory ventilation device for animals and an intelligent triggering method thereof, wherein the respiratory ventilation device has an intelligent triggering function, a user does not need to set a triggering level of the animal during use, only characteristic information corresponding to the animal is acquired, a target respiratory rate range of the animal is adaptively determined according to individual differences of the animal, and the triggering sensitivity acting on the animal can be automatically adjusted according to the monitored respiratory rate of the animal in the ventilation process, so that the monitored respiratory rate of the animal meets the requirement of the target respiratory rate range.

Description

[0001] This application is a divisional application of the following parent case:

[0002] The parent application number is 202011581911.X, and the title is: A respiratory ventilation device for animals and its intelligent triggering method. Technical Field

[0003] This application relates to a respiratory ventilation device for animals and a smart triggering method thereof. Background Technology

[0004] For some common mammals, their breathing methods are basically the same as humans, involving the periodic and rhythmic inhalation and exhalation of gases, absorbing oxygen and expelling carbon dioxide to achieve gas exchange. When some sick or injured animals are unable to breathe spontaneously, mechanical ventilation can be used to help them breathe, such as providing respiratory support to animals lacking spontaneous breathing through veterinary ventilators.

[0005] In medical animal experiments, veterinary medicine, and pet healthcare, anesthesia is frequently required, and one common method is inhalation anesthesia. Inhalation anesthesia involves the anesthetic drug entering the alveoli through respiration and then the bloodstream. The anesthesia is maintained when the concentration of the anesthetic drug in the blood reaches equilibrium with the inhaled concentration. After the inhalation of the anesthetic drug stops, the drug in the blood is exhaled through the alveoli, meaning it is largely expelled from the body without being metabolized. This results in rapid drug clearance, minimal damage to internal organs, and minimal impact on experimental results. The recovery time from inhalation anesthesia is very short; the animal can wake up quickly once the inhalation of the anesthetic gas is stopped.

[0006] Currently, veterinary anesthesia machines are the primary equipment for achieving inhalation anesthesia in animals. Most veterinary anesthesia machines on the market are simple machines without microprocessors, containing only mechanical and gas circuit components. The entire anesthesia process relies mainly on the laboratory personnel or veterinarians manually squeezing the sac. Monitoring is limited to mechanical pressure gauges. Because these machines are not fully automated, the difficulty for users in administering anesthesia to animals is significantly increased. Furthermore, there are veterinary anesthesia machines on the market that are modified from human anesthesia machines. These machines inherit their parameter settings entirely from human anesthesia machines, resulting in numerous parameter types, high technical complexity, and difficulty in understanding and setting them. From the user's perspective, laboratory personnel and veterinarians will experience anxiety and confusion when faced with similar complex parameter settings to human anesthesia machines, further increasing the operational difficulty. Summary of the Invention

[0007] To address the problem that existing veterinary anesthesia machines are difficult to operate, this application provides an animal respiratory ventilation device and its intelligent triggering method.

[0008] According to a first aspect, one embodiment provides a respiratory ventilation device for animals, comprising:

[0009] Gas source interface, used to connect to an external gas source;

[0010] Anesthetic delivery device, used to provide a gas mixed with anesthetic drugs;

[0011] A breathing circuit is used to connect the gas source interface to the animal's respiratory system, so as to input a preset gas into the animal and discharge some of the gas exhaled by the animal into the external environment; the preset gas is the gas provided by the external gas source and the gas mixed with anesthetic output by the anesthetic output device.

[0012] A respiratory assist device is used to provide power to introduce the preset gas into the animal or to expel part of the gas exhaled by the animal into the external environment;

[0013] The processor is configured to acquire characteristic information corresponding to the animal, determine the target respiratory rate range of the animal based on the characteristic information, acquire the monitored respiratory rate of the animal during ventilation, and adjust the trigger sensitivity of the ventilation device acting on the animal during ventilation based on the monitored respiratory rate of the animal during ventilation and the target respiratory rate range, so that the monitored respiratory rate of the animal meets the requirements of the target respiratory rate range.

[0014] According to a second aspect, one embodiment provides an intelligent triggering method for an animal respiratory ventilation device, comprising: acquiring the target respiratory rate range of the animal;

[0015] The respiratory rate of the animal during ventilation was obtained;

[0016] The trigger sensitivity of the ventilation device acting on the animal during ventilation is adjusted according to the monitored respiratory rate of the animal during ventilation and the target respiratory rate range, so that the monitored respiratory rate of the animal meets the requirements of the target respiratory rate range.

[0017] Specifically, if the monitored respiratory rate is determined to be less than the lower limit of the target respiratory rate range, the current trigger sensitivity is increased; if the monitored respiratory rate is determined to be greater than the upper limit of the target respiratory rate range, the current trigger sensitivity is decreased; if the monitored respiratory rate is determined to be within the target respiratory rate range, the current trigger sensitivity remains unchanged.

[0018] The beneficial effects of this application are:

[0019] According to the above embodiments, an animal respiratory ventilation device and its intelligent triggering method are provided. The respiratory ventilation device has an intelligent triggering function. When in use, it can adaptively determine the target respiratory rate range of the animal according to the individual differences of the animal. It can also automatically adjust the triggering sensitivity applied to the animal according to the monitored respiratory rate of the animal during the ventilation process, so that the monitored respiratory rate of the animal meets the requirements of the target respiratory rate range. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the structure of an animal respiratory ventilation device in one embodiment;

[0021] Figure 2 This is a schematic diagram of the structure of an animal respiratory ventilation device in another embodiment;

[0022] Figure 3 This is a schematic diagram of the structure of an animal respiratory ventilation device in another embodiment;

[0023] Figure 4 A flowchart of an intelligent triggering method for an animal respiratory ventilation device in one embodiment;

[0024] Figure 5 A flowchart for adjusting the trigger sensitivity of the respiratory ventilation device on the animal during ventilation;

[0025] Figure 6 A flowchart of an intelligent triggering method for an animal respiratory ventilation device in another embodiment;

[0026] Figure 7 This is a flowchart of an intelligent triggering method for an animal respiratory ventilation device in another embodiment. Detailed Implementation

[0027] The present invention will now be described in further detail with reference to specific embodiments and accompanying drawings. Similar elements in different embodiments are referred to by associated similar element reference numerals. In the following embodiments, many details are described to facilitate a better understanding of this application. However, those skilled in the art will readily recognize that some features may be omitted in different situations, or may be replaced by other elements, materials, or methods. In some cases, certain operations related to this application are not shown or described in the specification. This is to avoid obscuring the core parts of this application with excessive description. For those skilled in the art, detailed description of these related operations is not necessary; they can fully understand the related operations based on the description in the specification and general technical knowledge in the art.

[0028] Furthermore, the features, operations, or characteristics described in the specification can be combined in any suitable manner to form various embodiments. At the same time, the steps or actions in the method description can be rearranged or adjusted in a manner obvious to those skilled in the art. Therefore, the various orders in the specification and drawings are only for the clear description of a particular embodiment and do not imply a necessary order, unless otherwise stated that a particular order must be followed.

[0029] The serial numbers assigned to components in this document, such as "first" and "second," are used only to distinguish the described objects and have no sequential or technical meaning. Unless otherwise specified, the terms "connection" and "linkage" used in this application include both direct and indirect connections (linkages).

[0030] This application discloses an animal respiratory ventilation device (hereinafter referred to as a respiratory ventilation device) in some embodiments. Please refer to [link / reference]. Figure 1 and Figure 2 The breathing ventilation device includes an air source interface 101, an anesthetic output device 102, a breathing assist device 103, a breathing circuit 104, and a processor 50, which are described in detail below.

[0031] Gas source interface 101 is used to connect to an external gas source (not shown in the figure). The gas source connected to gas source interface 101 provides gas, which can typically be oxygen, nitrous oxide (laughing gas), or air. In some embodiments, the gas source can be a compressed gas cylinder or a central gas supply source, supplying gas to the breathing ventilation device through gas source interface 101. The supplied gas types include oxygen (O2), nitrous oxide (N2O), and air. Gas source interface 101 can be connected to conventional components such as pressure gauges, pressure regulators, flow meters, pressure reducing valves, and N2O-O2 proportional control protection devices, enabling flow control of various gases (e.g., oxygen, nitrous oxide, and air). The gas input into gas source interface 101 enters the breathing circuit 104, forming a mixed gas with the existing gas in the breathing circuit 104.

[0032] The anesthetic delivery device 102 is used to provide anesthetic drugs, such as a gas mixed with anesthetic drugs. Typically, the anesthetic drug is mixed in gaseous form with fresh gas introduced through the gas source interface 101 and delivered together into the breathing circuit 104. In one specific embodiment, the anesthetic delivery device 102 is implemented using an anesthetic vaporizer. The anesthetic drug is typically liquid and stored in the vaporizer. Optionally, the vaporizer may include a heating device for heating the anesthetic drug to volatilize it, generating anesthetic vapor. The anesthetic delivery device 102 is connected to the conduit of the gas source interface 101, and the anesthetic vapor mixes with the fresh gas introduced through the gas source interface 101 before being delivered together into the breathing circuit 104.

[0033] The breathing circuit 104 connects the gas source interface 101 to the animal's respiratory system to supply a preset gas to the animal and expel some of the exhaled gas to the external environment. Typically, the breathing circuit 104 includes two branches: an exhalation branch and an inhalation branch. The exhalation branch directs the animal's exhaled gas to an exhaust port, which can lead to the external environment or a dedicated gas recovery device. The inhalation branch provides the animal with oxygen, air, or a gas mixed with anesthetic. For example, gas supplied from the gas source interface 101 enters the inhalation branch and then enters the animal's lungs through the breathing interface.

[0034] In some embodiments, the breathing circuit 104 may include an inspiratory branch 104b and an expiratory branch 104a. In some embodiments, it may also include a soda lime container 104c. The inspiratory branch 104b and the expiratory branch 104a are connected to form a closed loop, and the soda lime container 104c is disposed on the pipeline of the expiratory branch 104a. Fresh gas introduced by the gas source interface 101 is input through the inlet of the inspiratory branch 104b and provided to the animal through the breathing interface 105 disposed at the outlet of the inspiratory branch 104b. The breathing interface 105 may be a face mask, a nasal cannula, or an endotracheal cannula. In a preferred embodiment, a one-way valve is provided on the inspiratory branch 104b, which opens during the inspiratory phase and closes during the expiratory phase. A one-way valve is also provided on the expiratory branch 104a, which closes during the inspiratory phase and opens during the expiratory phase. The inlet of the exhalation branch 104a is connected to the breathing interface 105. When the animal exhales, the exhaled gas enters the soda lime container 104c through the exhalation branch 104a. The carbon dioxide in the exhaled gas is filtered out by the substance in the soda lime container 104c. The gas after the carbon dioxide is filtered out is then recirculated into the inhalation branch 104b.

[0035] The respiratory assist device 103 provides power to supply a preset gas to the animal or to expel a portion of the animal's exhaled gas into the external environment. For example, the respiratory assist device 103 is connected to the respiratory circuit 104. The preset gas here is a mixture of gas supplied by an external gas source and gas containing anesthetic drugs output by the anesthetic drug output device 102. In some specific embodiments, the respiratory assist device 103 is connected to the gas source interface 101 and the respiratory circuit 104, controlling the delivery of gas supplied by the external gas source to the animal through the respiratory circuit 104. In some specific embodiments, the respiratory assist device 103 mixes the fresh gas input from the gas source interface 101, the gas exhaled by the animal in the respiratory circuit 104, and the anesthetic drug output by the anesthetic drug output device 102, and outputs the mixture through the inhalation branch 104b to the respiratory interface 105 to drive the animal to inhale, and receives the animal's exhaled gas through the exhalation branch 104a. In some examples, the respiratory assist device 103 may include an expiratory controller and an inspiratory controller, wherein the expiratory controller is used to control the flow rate or pressure of the animal's exhaled gas according to control commands; and wherein the inspiratory controller is used to control the flow rate or pressure of the animal's inhaled gas according to control commands. In other examples, the expiratory controller may be located on the expiratory branch of the respiratory circuit 104, and is used to connect or disconnect the expiratory branch according to control commands; the inspiratory controller may be located on the inspiratory branch of the respiratory circuit 104, and is used to connect or disconnect the inspiratory branch according to control commands.

[0036] In some embodiments, the respiratory assist device 103 may include a mechanical ventilation module, the airflow channel of which is connected to the breathing circuit 104. During the anesthesia maintenance phase of surgery or when the animal has not regained spontaneous breathing, the mechanical ventilation module provides the animal with the power to breathe. In other embodiments, the respiratory assist device 103 also includes a manual ventilation module, the airflow channel of which is connected to the breathing circuit 104. During the induction phase before intubation in surgery, the manual ventilation module is typically used to assist the animal's breathing. When the respiratory assist device 103 includes both a mechanical ventilation module and a manual ventilation module, the mechanical or manual ventilation mode can be switched via a mechanical or manual switch (e.g., a three-way valve) to connect either the mechanical or manual ventilation module to the breathing circuit 104, thereby controlling the animal's breathing. Those skilled in the art should understand that, depending on specific needs, the anesthesia machine may include only a mechanical ventilation module or a manual ventilation module.

[0037] It should be noted that the animals in this embodiment mainly refer to mammals with respiratory systems, which connect to the external environment through the nasal cavity and perform gas exchange through the lungs. For example, these animals include dogs, cats, rats, cows, sheep, tigers, wolves, lions, leopards, pandas, etc.

[0038] In one specific embodiment, this application Figure 1 The animal ventilation device disclosed in the paper can be an anesthesia machine, which is mainly used to provide anesthetic gas and deliver the anesthetic gas to the animal's respiratory system through a breathing circuit, and to control the amount of anesthetic gas inhaled.

[0039] The processor 50 can connect to the respiratory assist device, sensors or valves in the air source interface, sensors or valves in the breathing circuit, etc., and can control the trigger sensitivity acting on the animal during ventilation.

[0040] In some embodiments, see Figure 3 The processor 50 can also be connected to some auxiliary components to form a breathing and ventilation device for animals. Some of the connected auxiliary components may include, for example, a sensor accessory 110, a power and battery management circuit 120, an input interface circuit 130, an external communication interface 140, a memory 30, and a display 70, which are described below.

[0041] In some embodiments, sensor accessory 110 may include sensors such as pressure sensor 111 and flow sensor 112, mainly used to collect some monitoring values ​​of the respiratory ventilation equipment (such as respiratory gas pressure and respiratory gas flow). Of course, different types of sensors can also be used to collect some physiological signals of animals (such as electrocardiogram, body temperature, blood pressure, etc.). It is understood that sensor accessory 110 can also be used in conjunction with signal acquisition circuit and front-end processing circuit to realize signal filtering, sampling, analog-to-digital conversion and other processing. Since these processing methods are conventional technologies in electronic circuits, they will not be described in detail here.

[0042] Figure 3 The flow sensor 112 is mainly used to collect the gas flow rate of the animal during ventilation. The gas flow rate during ventilation can refer to the inspiratory flow rate of the animal. For example, the flow sensor 112 can be a flow sensor located at the animal end, such as a flow sensor located at the animal interface; in this case, the gas flow rate is the gas flow rate collected by the flow sensor during inspiration. In one specific embodiment, there are multiple flow sensors 112, including inspiratory flow sensors and expiratory flow sensors located at the mechanical ventilation end. For example, for… Figure 3In the case of an anesthesia machine, the flow sensor 112 can be an inspiratory flow sensor located in the inspiratory branch 104b and an expiratory flow sensor located in the expiratory branch 104a; the gas flow rate here is the difference between the flow rates collected by the inspiratory and expiratory flow sensors during inspiration. In some embodiments, the flow sensor 112 can also be a Y-piece flow sensor, which directly measures the inflow and outflow velocities at the animal end as the gas flow rate. Of course, the energy acting on the animal's respiratory system during mechanical ventilation can be calculated using the gas flow rate throughout the entire respiratory period, including the gas flow rates during inspiration and expiration.

[0043] Figure 3 The pressure sensor 111 is primarily used to collect the gas pressure of an animal's respiration during ventilation. This pressure reflects the pressure acting on different sites within the animal's respiratory system during ventilation—such as airway pressure, intrathoracic pressure, carina pressure, intrapulmonary pressure, esophageal pressure, and intragastric pressure, among others. The pressure sensor 111 can be a catheter-type pressure sensor or a fiber optic pressure sensor, etc. By inserting the pressure sensor into the corresponding site of the animal's respiratory system, the pressure at that site can be collected. For example, inserting the pressure sensor into the animal's airway collects airway pressure; inserting it into the esophagus collects esophageal pressure; inserting it into the stomach collects intragastric pressure; inserting it into the carina inside the trachea collects carina pressure; inserting it into the stomach collects intragastric pressure; and inserting it into the thoracic cavity through an incision or other opening collects intrathoracic pressure.

[0044] The power and battery management circuit 120 can draw power from the grid or battery through the power interface, and then supply it to the processor 50 after processing, such as rectification and filtering. The power and battery management circuit 120 can also monitor, manage and protect the power obtained through the power interface.

[0045] The input interface circuit 130 is used to connect external input components, such as a keyboard, mouse, control panel, touch screen, etc. Users can use these input components to provide setting parameters and commands to the processor 50, such as inputting characteristic information corresponding to the animal and selecting the breathing trigger mode of the ventilation device. It can be understood that input methods include button input, knob input, cursor interaction input, touch interaction input, symbol and text selection input, etc., and users can freely choose any input method according to their actual needs.

[0046] The external communication interface 140 can be one or a combination of Ethernet, Token Ring, Token Bus, and Fiber Distributed Data Interface (FDDI) as the backbone of these three networks; it can also be one or a combination of wireless interfaces such as infrared, Bluetooth, Wi-Fi, and WMTS communication; or it can be one or a combination of wired data connection interfaces such as RS232 and USB. The external communication interface 140 can also be one or a combination of wireless and wired data transmission interfaces. The external communication interface 140 can be connected to medical management systems, other monitoring equipment, user terminals, etc., to achieve remote data transmission and remote monitoring capabilities.

[0047] The memory 30 can be used to store data or programs, such as data acquired by the processor 50 and data generated during processing. Acquired data includes characteristic information corresponding to the animal and monitored respiratory rate during ventilation. Data generated during processing includes the animal's target respiratory rate range and trigger sensitivity. It can be understood that data acquired by the processor 50, data generated through calculation, or image frames generated by the processor (which can be 2D or 3D images) can all be stored in the memory 30. Of course, the memory 30 can also store a graphical user interface, one or more default image display settings, and programming instructions for the processor. The memory 30 can be a tangible and non-transitory computer-readable medium, such as flash memory, RAM, ROM, EEPROM, etc.

[0048] The display 70 is used to display visual data or images generated by the processor 50; of course, the display 70 can also display some graphical user interfaces to distribute user operation options. The display 70 can be a CTR, LCD, LED, 3D or other types of display screens, and may even have touch interaction capabilities as a human-computer interaction interface.

[0049] In some embodiments of the present invention, the respiratory ventilation device has an automatic trigger control mode. The respiratory ventilation device may have only an automatic trigger control mode, or it may have both an automatic trigger control mode and a manual trigger control mode; wherein the manual trigger control mode refers to the user directly adjusting the trigger sensitivity value manually, and the automatic trigger control mode will be described in detail below. In the example where the respiratory ventilation device can have both automatic and manual trigger control modes, the automatic trigger control mode may be set as the default mode. In the example where the respiratory ventilation device can have both automatic and manual trigger control modes, physical or virtual buttons may be provided for the user to select and switch the current trigger control mode.

[0050] The automatic trigger control mode is explained below.

[0051] In automatic trigger control mode, the processor 50 can automatically adjust the trigger sensitivity of the respiratory ventilation device acting on the animal during ventilation, so that the animal's monitored respiratory rate meets the requirements of the target respiratory rate range. For example, in some embodiments, the processor 50 can adjust the trigger sensitivity of the respiratory ventilation device acting on the animal during ventilation based on the animal's monitored respiratory rate and the target respiratory rate range during ventilation.

[0052] In some specific embodiments, the processor 50 acquires the target respiratory rate range of the animal; and the processor 50 is used to acquire the monitored respiratory rate of the animal during ventilation, and adjust the trigger sensitivity of the ventilation device acting on the animal during ventilation based on the monitored respiratory rate and the target respiratory rate range of the animal during ventilation, so that the monitored respiratory rate of the animal meets the requirements of the target respiratory rate range.

[0053] The processor 50 acquires the target respiratory rate range of an animal in several ways, which are explained in detail below.

[0054] In some embodiments, the processor 50 acquires characteristic information corresponding to the animal and determines the target respiratory rate range for the animal based on the characteristic information. In some embodiments, the characteristic information corresponding to the animal may include individual information about the animal and / or numerical values ​​of ventilation parameters corresponding to the animal, as described below.

[0055] In one specific embodiment, the characteristic information corresponding to the animal acquired by the processor 50 includes the animal's individual information. The processor 50 can then determine the target respiratory rate range for the animal based on this individual information. It is understood that the animal's individual information may include one or more of the following: species, weight, age, and body size. Species refers to the animal's species attribute, such as dog, cat, rat, cow, sheep, tiger, wolf, lion, leopard, panda, etc.; body size refers to whether the animal is a large or small animal. Large animals include, for example, cows, sheep, tigers, wolves, lions, and leopards, while small animals include, for example, dogs and cats. A built-in lookup table related to animal species and body size can be used, allowing the processor 50 to determine whether an animal is a large or small animal by having the user input the animal's species, or it can directly provide an option for the user to select whether the current animal is a large or small animal. Since the animal's weight is related to the required ventilation support, the processor 50 can also determine the target respiratory rate range based on the acquired animal weight. In some examples, after acquiring the animal species / body size, the processor 50 can further acquire the animal weight to determine a more appropriate target respiratory rate range, which is more beneficial when there are large differences in body size among animals of different ages. Since species and body size are qualitative parameters, they often require manual judgment before input. Weight, on the other hand, is a quantitative parameter that can be directly measured and input. If the animal's actual birth date is known, age can be directly quantitatively set; otherwise, it needs to be qualitatively determined and input manually. Therefore, in some embodiments, the animal's individual information can be obtained from... Figure 3 The input components (such as keyboards, control panels, mice, touch screens, etc.) connected to the input interface circuit 130 are obtained through user input settings. The input settings include keyboard input, knob input, touch interaction input, cursor interaction input, text and symbol selection input, etc.

[0056] In one scenario, the processor 50 can input the animal's individual information into a preset function to calculate the animal's target respiratory rate range, for example, the calculation process can be expressed by a formula as follows:

[0057] (RR0, RR1) = f(x1);

[0058] Where RR0 and RR1 are the lower and upper limits of the target respiratory rate range, respectively, x1 is the individual information of the animal, and f() is a preset function.

[0059] Of course, to facilitate adjustments to the above calculation process by technicians / users to achieve a suitable application state, the processor 50 can also respond to setting instructions to set the coefficients of the function (such as parameters in function f), thereby achieving the purpose of adjusting the function parameters. It is understood that setting instructions can be generated by the user operating the input device or by the system initializing the default configuration; there is no strict limitation here. Therefore, in some embodiments, the coefficients of the function can be determined by... Figure 3 The input components (such as keyboards, control panels, mice, touch screens, etc.) connected to the input interface circuit 130 are obtained through user input settings. The input settings include keyboard input, knob input, touch interaction input, cursor interaction input, text and symbol selection input, etc.

[0060] In another scenario, processor 50 can determine the animal's target respiratory rate range using a lookup table. For example, processor 50 obtains a lookup table that includes the correspondence between individual information and target respiratory rate ranges. Given the individual information of the animal, processor 50 can directly determine the animal's target respiratory rate range from the lookup table. For instance, Table 1 lists the correspondence between animal type, weight, and target respiratory rate for various animals. If processor 50 determines the animal type to be a dog, it can directly determine that the dog's target respiratory rate range is 16–20 bpm.

[0061] Table 1

[0062] guinea pig 0.27～0.94 70～110 rabbit 2～3 35～50 cat 2～3 20～30 dog 10～20 16～20

[0063] It should be noted that in Table 1, body weight is one of the individual parameters of the animal. Furthermore, the function f and the lookup table can be pre-configured in memory 30, and the processor 50 can directly call the function and read data from the lookup table. It should be noted that Table 1 is merely an example for illustrative purposes and is not intended to limit or represent that this is the only practical solution. In particular, it is not intended to limit the strong correlation between animal type and body weight when determining the target respiratory rate range. For example, the target respiratory rate range can also be determined solely based on body weight.

[0064] In another specific embodiment, the feature information acquired by the processor 50 corresponding to the animal includes the values ​​of ventilation parameters corresponding to the animal. The processor 50 can then determine the animal's target respiratory rate range based on the values ​​of these ventilation parameters. It is understood that the animal's ventilation parameters may include one or more of the following: tidal volume, gas flow rate, driving pressure, positive end-expiratory pressure, and respiratory ratio; for example... Figure 3The ventilation parameters of the animal can be detected by sensor accessories 111, including pressure sensor 111 and flow sensor 112. For example, the flow sensor 112 collects the gas flow rate value of the animal during ventilation, and the pressure sensor 111 collects the gas pressure value of the animal during ventilation (such as the value of driving pressure and positive end-expiratory pressure). Tidal volume is obtained by integrating the gas flow rate of each inhalation or exhalation over the inhalation or exhalation time. In addition, the respiratory ratio refers to the ratio between inspiratory and expiratory time, and is also a way to define time switching. During triggered assisted ventilation, the ventilator will automatically adjust the inspiratory-expiratory ratio as the animal's spontaneous respiratory rate increases, always maintaining a normal standard state.

[0065] It should be noted that the ventilation parameters listed here can be not only monitored values ​​obtained through sensors, but also user-set values ​​obtained by the user through input components. For example, the ventilation parameter values ​​can be determined by... Figure 3 The input components (such as keyboards, control panels, mice, touch screens, etc.) connected to the input interface circuit 130 are obtained through user input settings. The input settings include keyboard input, knob input, touch interaction input, cursor interaction input, text and symbol selection input, etc.

[0066] In one scenario, the processor 50 can input the animal's ventilation parameters into a preset function to calculate the animal's target respiratory rate range, for example, the calculation process can be expressed by the formula:

[0067] (RR0, RR1) = g(x2);

[0068] Where RR0 and RR1 are the lower and upper limits of the target respiratory rate range, respectively, x2 is the animal's ventilation parameter, and g() is a preset function.

[0069] For example, if VT represents the tidal volume monitoring value of an animal, x2 = VT can be input into a preset function, and then RR0 and RR1 can be calculated.

[0070] RRtarget = 112.5 * VT -0.7832 ;

[0071] RR0 = RRtarget - 30;

[0072] RR1 = RRtarget + 30.

[0073] Where RRtarget is a process variable, and the values ​​112.5, 0.7832, and 30 are the coefficients of the function.

[0074] Of course, to facilitate adjustments to the above calculation process by technicians / users to achieve a suitable application state, the processor 50 can also respond to setting instructions to set the coefficients of the function. It is understood that the setting instructions can be generated by the user operating the input device or by the system initializing the default configuration; no strict limitation is imposed here. In some embodiments, the coefficients of the function can be obtained by user input settings through the input device connected to the processor 50.

[0075] In another scenario, processor 50 can determine the animal's target respiratory rate range using a lookup table. For example, processor 50 can obtain a lookup table that includes the correspondence between ventilation parameter values ​​and target respiratory rate ranges. After obtaining the animal's ventilation parameter values ​​from the lookup table, processor 50 can directly determine the animal's target respiratory rate range. For instance, Table 2 below lists the correspondence between tidal volume values ​​and target respiratory rates for various animals. If processor 50 obtains an animal's tidal volume value of 4–25 ml, it can directly determine that the target respiratory rate range is 70–110 bpm.

[0076] Table 2

[0077] 4～20 70～110 20～70 35～50 70～150 20～30 150～300 16～20

[0078] It should be noted that function g and the lookup table can be pre-configured in memory 30, and processor 50 can directly call the function and read data from the lookup table. It should also be noted that Table 2 is merely an example for illustrative purposes and is not intended to limit or indicate that this is the only possible approach.

[0079] In some embodiments, the processor 50 determines the animal's target respiratory rate range using both the animal's individual information and the values ​​of ventilation parameters. For example, the animal's individual information and the values ​​of ventilation parameters can be input into a preset function to calculate the animal's target respiratory rate range. In some embodiments, the processor 50 can also respond to a setting instruction to set the coefficients of the function, thereby adjusting the function parameters. In other embodiments, the processor 50 can determine the animal's target respiratory rate range using the animal's individual information, the values ​​of ventilation parameters, and a lookup table. This lookup table includes the correspondence between individual information, the values ​​of ventilation parameters, and the target respiratory rate range; Table 3 is an example.

[0080] Table 3

[0081] guinea pig 0.27～0.94 4～25 70～110 rabbit 2～3 20～70 35～50 cat 2～3 20～70 20～30 dog 10～20 150～300 16～20

[0082] In another specific embodiment, the feature information corresponding to the animal acquired by the processor 50 includes the animal's individual information. The processor 50 can then determine the setting values ​​for the ventilation parameters used to set the respiratory ventilation device based on the animal's individual information, and further determine the animal's target respiratory rate range based on the ventilation parameter setting values. The animal's individual information and the ventilation parameter setting values ​​have been described in detail above and will not be repeated here. The processor 50 can directly set the respiratory ventilation device based on the determined ventilation parameter setting values, or it can be displayed on the display 70 for user reference.

[0083] Here, individual animal information can be obtained from... Figure 3 The input components (such as keyboards, control panels, mice, touchscreens, etc.) connected to the input interface circuit 130 are obtained through user input settings, while the ventilation parameter settings are obtained by the processor 50 after further processing of the individual information. This is because in some cases, it is more accurate to determine the animal's target respiratory rate range directly using the ventilation parameter settings (rather than individual information).

[0084] In one scenario, the processor 50 inputs the animal's individual information into a preset function to calculate the settings for the ventilation parameters of the breathing ventilation device. For example, the calculation process can be expressed as a formula.

[0085] Q = h(x1);

[0086] Where Q is the ventilation parameter setting (which can represent a single value or a range of values), x1 is the individual information of the animal, and h() is a preset function.

[0087] It is understandable that, given the set value Q of the ventilation parameters, the lower and upper limits of the target respiratory rate range can be calculated using the formula (RR0, RR1) = g(x2), or the target respiratory rate range of the animal can be directly determined from a pre-configured lookup table.

[0088] Of course, to facilitate adjustments to the above calculation process by technicians / users to achieve a suitable application state, the processor 50 can also respond to setting instructions to set the coefficients of functions h and g. It can be understood that setting instructions can be generated by the user operating the input components or by the system initialization default configuration; no strict limitation is imposed here. For example, the coefficients of the functions can be obtained through user input settings via input components connected to the processor 50. Input setting methods include keyboard input, knob input, touch interaction input, cursor interaction input, text and symbol selection input, etc.

[0089] It should be noted that functions h, g, and the lookup table can all be pre-configured in memory 30, and processor 50 can directly call the functions and read data from the lookup table.

[0090] In another scenario, processor 50 can first determine the animal's ventilation parameter settings by looking up a table, and then further determine the animal's target respiratory rate range. For example, processor 50 obtains a lookup table that includes individual information, the correspondence between ventilation parameter settings and target respiratory rate ranges. Based on the animal's individual information, processor 50 can directly determine the animal's ventilation parameter settings from the lookup table. Then, by continuing to search the lookup table and obtaining the animal's ventilation parameter settings, it can further determine the animal's target respiratory rate range from the table. For example, Table 1 lists the correspondence between various animal types, weights, tidal volumes, and target respiratory rates. If processor 50 determines the animal type to be a rabbit, it can directly determine that the rabbit's tidal volume range is 20–70 ml, and based on the type and tidal volume, it can further determine that the rabbit's target respiratory rate range is 35–50 bpm.

[0091] In another specific embodiment, the processor 50 directly obtains the animal's target respiratory rate range, where the upper and lower limits of the target respiratory rate range can be determined by... Figure 3 The input components (such as keyboards, control panels, mice, touchscreens, etc.) connected to the input interface circuit 130 are obtained through user input settings. Input settings can be achieved through keyboard input, knob input, touch interaction input, cursor interaction input, and text and symbol selection input. For example, a user might determine the animal's type, age, and size, and then, based on common sense or research, manually determine the animal's target respiratory rate range. In this case, the user only needs to input the upper and lower limits, and the processor 50 can quickly obtain the animal's target respiratory rate range based on the input upper and lower limits.

[0092] The above explains how the processor 50 obtains the target respiratory rate range of the animal. The following explains how the processor 50 adjusts the trigger sensitivity of the respiratory ventilation device.

[0093] In some embodiments, the processor 50 adjusts the trigger sensitivity of the ventilation device on the animal during ventilation based on the monitored respiratory rate and the target respiratory rate range during ventilation. For example, (1) when it is determined that the monitored respiratory rate is less than the lower limit of the target respiratory rate range, the processor 50 increases the current trigger sensitivity; (2) when it is determined that the monitored respiratory rate is greater than the upper limit of the target respiratory rate range, the processor 50 decreases the current trigger sensitivity; (3) when it is determined that the monitored respiratory rate is within the target respiratory rate range, the processor 50 maintains the current trigger sensitivity unchanged.

[0094] In one specific embodiment, the processor 50 increases the current trigger sensitivity in two ways: First, by increasing the trigger level based on the current trigger sensitivity level (including inspiratory trigger sensitivity and / or expiratory trigger sensitivity) of the breathing ventilation device; second, by directly adjusting the value of the trigger sensitivity. If the currently used trigger sensitivity is flow-triggered, the flow-triggered threshold can be decreased; if the currently used trigger sensitivity is pressure-triggered, the pressure-triggered threshold can be decreased. It can be understood that regardless of the method used, the purpose is to reduce the amount of airflow or pressure change required for triggering, thereby making the animal's inspiratory / expiratory triggering easier to trigger. It can be understood that after increasing the current trigger sensitivity, the processor 50 will control... Figure 2 The respiratory assist device 103 in the middle can more easily change the gas flow direction in the respiratory circuit, and at this time only a small breathing force is needed for the animal to achieve the respiratory phase transition.

[0095] In one specific embodiment, the processor 50 reduces the current trigger sensitivity in two ways: First, by reducing the trigger level based on the current trigger sensitivity level (including inspiratory trigger sensitivity and / or expiratory trigger sensitivity) of the respiratory ventilation device; second, by directly adjusting the trigger sensitivity value. If the currently used trigger sensitivity is flow-triggered, the flow-triggered threshold can be increased; if the currently used trigger sensitivity is pressure-triggered, the pressure-triggered threshold can be increased. It can be understood that regardless of the method used, the purpose is to increase the amount of pressure change or airflow change required for triggering, thereby making the animal's inspiratory / expiratory triggering difficult to trigger. It can be understood that after increasing the current trigger sensitivity, the processor 50 will control... Figure 2 The respiratory assist device 103 in the middle is more difficult to change the gas flow direction in the respiratory circuit. At this time, the animal needs to breathe with greater force to achieve the respiratory phase transition.

[0096] It's important to note that there's a parameter in respiratory ventilation equipment that relates to the synchronization between the animal and the device: trigger sensitivity. Trigger sensitivity is divided into inspiratory trigger sensitivity and expiratory trigger sensitivity, depending on the respiratory phase. For example, inspiratory trigger sensitivity is the threshold at which the animal's initial inhalation creates negative pressure in the inspiratory tubing, which is detected by a specific sensor and triggers the ventilator for mechanical ventilation. In essence, trigger sensitivity represents the respiratory effort required for the ventilator to activate. Inspiratory trigger sensitivity can be categorized into several levels, such as very low, low, medium, high, and very high. Different levels require different triggering forces. For instance, if the sensitivity is set to very low, a larger inspiratory effort is needed to activate the machine; conversely, if the inspiratory sensitivity is set to very high, even a slight inspiratory flow can trigger the machine.

[0097] Ventilation devices typically have two treatment pressures: inspiratory pressure and expiratory pressure. Inspiratory pressure helps the animal deliver air to its lungs, so it's generally higher. Expiratory pressure is activated after the animal has inhaled sufficient air; the machine actively lowers this pressure to help expel waste gases from the lungs. During ventilation, the machine needs to switch freely between these two pressures based on the animal's breathing status, and this switching is achieved through trigger sensitivity. When the animal inhales, the machine senses the inspiratory airflow and increases the pressure; conversely, when the animal exhales, the machine senses a decrease in inspiratory airflow and actively lowers the pressure to help expel waste gases. Therefore, trigger sensitivity directly affects the synchronization between the animal and the machine.

[0098] In animal ventilation equipment, the trigger sensitivity can be adjusted autonomously according to the animal's respiratory status. For example, if the animal's respiratory rate is fast but its breathing strength is poor, the trigger sensitivity needs to be adaptively increased to make it more sensitive. If the animal's spontaneous breathing is good, the trigger sensitivity can be set lower. Therefore, the trigger sensitivity should be flexibly set according to the animal's respiratory condition to ensure that the monitored respiratory rate meets the target respiratory rate range.

[0099] Furthermore, before or during expiratory ventilation of an animal using the ventilation device, the processor 50 can also acquire the current ventilation control mode of the ventilation device. If the processor 50 determines that the current mode is volume control or pressure control based on user manual selection, system default, or other methods, regardless of the selected control mode, the adjusted trigger sensitivity includes the sensitivity of flow rate triggering and / or pressure triggering. The gas flow rate can be measured using... Figure 3 The flow rate sensor 112 is used for measurement, while the gas pressure is measured using the pressure sensor 111. For example, in some embodiments, if the ventilation control mode acquired by the processor 50 is a capacity control mode, then in the capacity control mode, either the flow rate trigger sensitivity or the pressure trigger sensitivity can be used; if the ventilation control mode acquired by the processor 50 is a pressure control mode, then in the pressure control mode, either the pressure trigger sensitivity or the flow rate trigger sensitivity can be used. It can be understood that the specific trigger sensitivity method can be selected by the user or set by the system default, and there is no strict restriction here.

[0100] Furthermore, when the processor 50 uses flow rate triggering sensitivity and / or pressure triggering sensitivity, the current trigger sensitivity can be increased by decreasing the trigger threshold corresponding to the flow rate triggering sensitivity and / or pressure triggering sensitivity; similarly, the current trigger sensitivity can be decreased by increasing the trigger threshold corresponding to the flow rate triggering sensitivity and / or pressure triggering sensitivity. This will be explained below. Flow rate triggering is a positive trigger, and pressure triggering is a negative trigger. When adjusting the trigger sensitivity in this invention, the increase or decrease of the trigger threshold for flow rate triggering and the trigger threshold for pressure triggering refer to increasing or decreasing the absolute value of the corresponding trigger threshold.

[0101] It's important to note that the flow rate trigger sensitivity here refers to the inspiratory flow rate that triggers assisted ventilation. It can also be considered the threshold value at which assisted ventilation is initiated during mechanical ventilation. For example, if the airway flow rate is 0 at the end of expiration, as inspiration begins, the inspiratory rate gradually increases. When the device senses that the inspiratory rate reaches the set flow rate trigger threshold (the flow rate trigger sensitivity value), it initiates assisted ventilation. A higher flow rate trigger sensitivity makes it less likely to initiate assisted ventilation. If the animal is not breathing spontaneously or is under general anesthesia with muscle relaxation, and you don't want external signals to falsely trigger assisted ventilation, you can set the flow rate trigger threshold higher. Conversely, if the animal is breathing spontaneously or you want to restore spontaneous breathing, you should set the flow rate trigger threshold lower.

[0102] It should be noted that the pressure trigger sensitivity here refers to the inspiratory pressure value at which assisted ventilation is initiated based on changes in airway pressure. For example, when inspiration begins, the instantaneous airway pressure decreases compared to the stable expiratory phase. When the device senses that the airway pressure change reaches the set pressure trigger threshold, it initiates assisted ventilation.

[0103] Therefore, it's understandable that respiratory triggering mechanisms typically fall into two categories: pressure triggering and flow triggering. Because breathing equipment and the animal's airway can generate additional resistance, the trigger sensitivity should be set at a relatively sensitive level to reduce the extra work required for inhalation. Compared to pressure triggering, flow triggering can further reduce the animal's respiratory work, provides better synchronization with the animal, and results in a more comfortable breathing state. If the sensitivity of flow triggering is set too sensitively, even a slight change in flow rate within the airway can cause automatic triggering, which may actually lead to respiratory discomfort.

[0104] In some embodiments, before the breathing ventilation device performs expiratory ventilation on the animal, the processor 50 can directly obtain the initial value of the system's default trigger sensitivity, or automatically initialize the initial value of the trigger sensitivity. In one specific embodiment, the processor 50 calculates the pressure trigger sensitivity based on the animal's characteristic information (such as weight, tidal volume, etc.), and sets it as the initial value of the breathing ventilation device's trigger sensitivity in, for example, an automatic trigger control mode. For instance, the pressure trigger sensitivity can be calculated using the following formula.

[0105] T = e(x3);

[0106] Where T is the initial sensitivity value, x3 is the animal's characteristic information, and e() is a preset function.

[0107] Understandably, to facilitate adjustments to the above calculation process by technicians / users to achieve a suitable application state, the processor 50 can also respond to setting instructions to set the coefficients of function e. It is understood that setting instructions can be generated by the user operating the input device or by the system's initial default configuration; no strict limitation is imposed here. For example, the coefficients of the function can be obtained through user input settings via the input device connected to the processor 50. Input settings can include keyboard input, knob input, touch interaction input, cursor interaction input, text and symbol selection input, etc. Furthermore, function e can be pre-configured in memory 30, and the processor 50 can directly call the function.

[0108] Of course, in some cases, after the processor 50 calculates the sensitivity of pressure triggering based on the animal's characteristic information (such as weight, tidal volume, etc.), it can also set it as the initial value of the triggering sensitivity of the breathing ventilation device in manual triggering control mode, which can avoid the user manually inputting the initial value and simplify the operation process.

[0109] In another specific embodiment, the processor 50 can use a lookup table to obtain the initial value of the trigger sensitivity. For example, Table 2 lists the correspondence between tidal volume and the initial value T0 of the trigger sensitivity. If the animal's tidal volume is 200, the processor 50 can directly set the initial value of the trigger sensitivity of the breathing ventilation device, that is, the initial value of the flow rate trigger sensitivity is 1.0 L / min, and the initial value of the pressure trigger sensitivity is -1.0 cmH2O.

[0110] Table 2

[0111]

[0112] The above is a description of the respiratory ventilation devices in some embodiments of this application.

[0113] In some embodiments of this application, an intelligent triggering method for an animal respiratory ventilation device is also disclosed. The animal respiratory ventilation device involved herein, or the respiratory ventilation device, can be any of the respiratory ventilation devices described in any of the embodiments herein. Figure 4 This is a flowchart of an intelligent triggering method for an animal respiratory ventilation device in one embodiment of this application. The method mainly includes steps 410-430, which are described below.

[0114] Step 410: Obtain the target respiratory rate range for the animal.

[0115] In some embodiments, to adaptively adjust the target respiratory rate range of an animal based on individual differences, characteristic information corresponding to the animal can be acquired, and then the target respiratory rate of the animal can be determined based on the characteristic information. In some embodiments, the characteristic information corresponding to the animal may include individual information about the animal and / or numerical values ​​of ventilation parameters.

[0116] In one specific embodiment, if the characteristic information corresponding to the animal includes the animal's individual information, then the target respiratory rate range of the animal is determined based on the animal's individual information. It is understood that the animal's individual information may include one or more of the following: species, weight, age, and body size.

[0117] In one scenario, the animal's individual information is input into a pre-defined function to calculate the animal's target respiratory rate range, specifically expressed by the formula:

[0118] (RR0, RR1) = f(x1);

[0119] Where RR0 and RR1 are the lower and upper limits of the target respiratory rate range, respectively, x1 represents the individual information of the animal, and f() is a preset function. Of course, to facilitate adjustments to the above calculation process by technicians / users to achieve a suitable application state, the processor 50 can also respond to setting instructions to set the coefficients of the function, thereby achieving the purpose of adjusting the function parameters.

[0120] In another scenario, a lookup table can be used to determine the animal's target respiratory rate range. For example, a lookup table can be obtained, which should include the correspondence between individual information and target respiratory rate ranges. Then, based on the lookup table and with the individual information of the animal available, the animal's target respiratory rate range can be directly determined from the table. For instance, in Table 1 above, given the animal's type and weight, the animal's target respiratory rate range can be directly looked up.

[0121] In another specific embodiment, if the characteristic information corresponding to the animal includes the values ​​of the animal's ventilation parameters, then the target respiratory rate range of the animal can be determined based on the values ​​of the animal's ventilation parameters. It is understood that the animal's ventilation parameters may include one or more of tidal volume, gas flow rate, driving pressure, positive end-expiratory pressure, and respiratory ratio.

[0122] In one scenario, the animal's ventilation parameters can be input into a preset function to calculate the animal's target respiratory rate range, specifically expressed by the formula:

[0123] (RR0, RR1) = g(x2);

[0124] Where RR0 and RR1 are the lower and upper limits of the target respiratory rate range, respectively, x2 is the animal's ventilation parameter, and g() is a preset function. Of course, to facilitate adjustments to the above calculation process by technicians / users to achieve a suitable application state, the processor 50 can also respond to setting instructions to set the coefficients of this function.

[0125] In another scenario, a lookup table can be used to determine the animal's target respiratory rate range. For example, a lookup table can be obtained that corresponds to the values ​​of ventilation parameters and the target respiratory rate range. Then, after obtaining the animal's ventilation parameter values, the animal's target respiratory rate range can be directly determined from the table. For instance, in Table 1 above, given the animal's tidal volume values, the target respiratory rate range can be directly determined from the table.

[0126] In another specific embodiment, the acquired feature information corresponding to the animal includes the animal's individual information. Then, based on the animal's individual information, the setting values ​​of the ventilation parameters used to set the breathing ventilation device can be determined first, and the target respiratory rate range of the animal can be further determined based on the setting values ​​of the ventilation parameters.

[0127] In one scenario, the animal's individual information is input into a pre-defined function to calculate the settings for ventilation parameters of the breathing equipment. For example, the calculation process can be expressed as a formula.

[0128] Q = h(x1);

[0129] Where Q is the ventilation parameter setting (which can represent a single value or a range of values), x1 is the individual information of the animal, and h() is a preset function.

[0130] It is understandable that, given the set value Q of the ventilation parameters, the lower and upper limits of the target respiratory rate range can be calculated using the formula (RR0, RR1) = g(x2), or the target respiratory rate range of the animal can be directly determined from a pre-configured lookup table.

[0131] In another scenario, a lookup table can be used to first determine the animal's ventilation parameter settings, and then further determine the animal's target respiratory rate range. For example, a lookup table can be obtained, which should include individual information, the correspondence between ventilation parameter settings and target respiratory rate ranges. Based on the lookup table and with the animal's individual information available, the animal's ventilation parameter settings can be directly determined from the table. Then, by continuing to search the lookup table and obtaining the animal's ventilation parameter settings, the target respiratory rate range can be further determined from the table.

[0132] Another specific embodiment directly obtains the target respiratory rate range of the animal, where the upper and lower limits of the target respiratory rate range can be determined by... Figure 3 The input components (such as keyboards, control panels, mice, touchscreens, etc.) connected to the input interface circuit 130 are obtained through user input settings. Input settings can be achieved through keyboard input, knob input, touch interaction input, cursor interaction input, and text and symbol selection input. For example, a user might determine the animal's type, age, and size, and then, based on common sense or research, manually determine the animal's target respiratory rate range. In this case, the user only needs to input the upper and lower limits.

[0133] Step 420: Obtain the animal's respiratory rate during ventilation.

[0134] Monitoring respiratory rate refers to the real-time respiratory frequency of an animal during the respiratory process, which can be achieved using... Figure 3 The gas flow rate during ventilation can be collected using the flow sensor 112, and the gas pressure during ventilation can be collected using the pressure sensor 111. Therefore, the number of times the animal breathes per minute (i.e., respiratory rate) can be obtained based on the periodic changes in gas pressure or gas volume.

[0135] Step 430: Adjust the trigger sensitivity of the ventilation device on the animal during ventilation based on the monitored respiratory rate and target respiratory rate range during the ventilation process, so that the monitored respiratory rate of the animal meets the requirements of the target respiratory rate range.

[0136] In one specific embodiment, see Figure 5 Step 430 may specifically include steps 431 to 434, which are explained below.

[0137] Step 431: Compare the animal's monitored respiratory rate with the target respiratory rate range. The comparison result is divided into three cases: the monitored respiratory rate is less than the target respiratory rate range, the monitored respiratory rate is greater than the target respiratory rate range, and the monitored respiratory rate is within the target respiratory rate range.

[0138] Step 432: If the monitored respiratory rate is determined to be less than the lower limit of the target respiratory rate range, increase the current trigger sensitivity.

[0139] In one specific embodiment, the current trigger sensitivity is improved in two ways: First, by increasing the trigger level based on the current trigger sensitivity level (including inspiratory and / or expiratory trigger sensitivity) of the breathing ventilation device; second, by directly adjusting the trigger sensitivity value. If the currently used trigger sensitivity is flow-triggered, the flow-triggered threshold can be decreased; if the currently used trigger sensitivity is pressure-triggered, the pressure-triggered threshold can be decreased. It can be understood that regardless of which method is used, the goal is to reduce the amount of airflow or pressure change required for triggering, thereby making the animal's inspiratory / expiratory triggering easier to activate.

[0140] Step 433: If the monitored respiratory rate is determined to be greater than the upper limit of the target respiratory rate range, reduce the current trigger sensitivity.

[0141] In one specific embodiment, the current trigger sensitivity is reduced in two ways: First, by lowering the trigger level based on the current trigger sensitivity level (including inspiratory and / or expiratory trigger sensitivity) of the breathing ventilation device; second, by directly adjusting the trigger sensitivity value. If the currently used trigger sensitivity is flow-triggered, the flow-triggered threshold can be increased; if the currently used trigger sensitivity is pressure-triggered, the pressure-triggered threshold can be increased. It can be understood that regardless of which method is used, the purpose is to increase the amount of pressure or airflow change required for triggering, thereby making the animal's inspiratory / expiratory triggering difficult to trigger.

[0142] Step 434: If it is determined that the monitored respiratory rate is within the target respiratory rate range, then the current trigger sensitivity remains unchanged.

[0143] In another embodiment, see Figure 6 Step 401 may be included before step 410.

[0144] Step 401: Obtain the current ventilation control mode of the breathing ventilation device and obtain the initial value of the trigger sensitivity.

[0145] For example, if the current mode is determined to be capacity control based on user manual selection or system default, the adjusted trigger sensitivity will be the sensitivity for flow rate triggering and / or the sensitivity for pressure triggering. The gas flow rate can be measured using... Figure 3 The flow rate sensor 112 is used for this purpose, while the gas pressure can be measured using... Figure 3The pressure sensor 111 is used for implementation. If the current control mode is determined by user manual selection, system default, or other methods, the adjusted trigger sensitivity is the sensitivity of pressure triggering and / or flow rate triggering. The specific trigger sensitivity to be used in which control mode can be selected by the user or set by the system default; no strict restriction is imposed here.

[0146] It's understandable that the initial value of the trigger sensitivity can be obtained either through the system default method or through function calculation. When using the latter method, the initial values ​​of the inspiratory trigger sensitivity and expiratory trigger sensitivity can be calculated by inputting the animal's characteristic information into a preset function. Therefore, in the initial stage of ventilation of the animal using the respiratory ventilation device, the initial values ​​of the inspiratory trigger sensitivity and expiratory trigger sensitivity are used as the initial trigger sensitivity. For example, the pressure trigger sensitivity can be calculated based on the animal's characteristic information (such as weight, tidal volume, etc.) and set as the initial value of the respiratory ventilation device's trigger sensitivity in automatic trigger control mode.

[0147] Of course, in addition to acquiring the current ventilation control mode before the breathing ventilation device performs expiratory ventilation on the animal, the current ventilation control mode can still be acquired during the breathing ventilation device's operation on the animal. This allows users to freely switch ventilation control modes and flexibly set the trigger sensitivity to flow rate trigger sensitivity or pressure trigger sensitivity according to actual needs.

[0148] In another embodiment, see Figure 7 Step 402 may be included before step 410.

[0149] Step 402: In automatic trigger control mode, adjust the trigger sensitivity of the breathing ventilation device on the animal during ventilation based on the monitored respiratory rate of the animal during ventilation and the target respiratory rate range.

[0150] To enable the ventilation equipment to enter automatic trigger control mode, it can autonomously enter this mode by responding to control commands. It should be noted that these control commands can be generated manually by the user through input components. For example, after the ventilation equipment is connected to the animal's respiratory system, the user only needs to press a button to generate a control command, which will then automatically adjust the trigger sensitivity applied to the animal during subsequent ventilation. Alternatively, the control command can be generated automatically by the system default, such as when the ventilation equipment is powered on, causing the equipment to immediately enter automatic trigger control mode.

[0151] Of course, in addition to being able to enter the automatic trigger control mode before the breathing ventilation equipment is used to ventilate the animal, it can also be entered automatically during the breathing ventilation equipment is used to ventilate the animal. This allows users to freely enter or exit the automatic trigger control mode to enter the manual mode, thus adapting to the actual needs of animal breathing ventilation.

[0152] This document describes various exemplary embodiments with reference to them. However, those skilled in the art will recognize that changes and modifications can be made to the exemplary embodiments without departing from the scope of this document. For example, various operational steps and components for performing operational steps can be implemented in different ways depending on the specific application or considering any number of cost functions associated with the operation of the system (e.g., one or more steps can be deleted, modified, or combined with other steps).

[0153] In the above embodiments, implementation can be achieved, in whole or in part, by software, hardware, firmware, or any combination thereof. Furthermore, as those skilled in the art will understand, the principles herein can be reflected in a computer program product on a computer-readable storage medium pre-loaded with computer-readable program code. Any tangible, non-transitory computer-readable storage medium may be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROMs, DVDs, Blu-ray discs, etc.), flash memory, and / or the like. These computer program instructions can be loaded onto a general-purpose computer, special-purpose computer, or other programmable data processing apparatus to form a machine, such that instructions executing on the computer or other programmable data processing apparatus can generate means for implementing a specified function. These computer program instructions can also be stored in a computer-readable storage medium that can instruct the computer or other programmable data processing apparatus to operate in a particular manner, such that instructions stored in the computer-readable storage medium can form an article of manufacture including means for implementing the specified function. The computer program instructions can also be loaded onto a computer or other programmable data processing apparatus to perform a series of operational steps on the computer or other programmable apparatus to produce a computer-implemented process, such that instructions executing on the computer or other programmable apparatus can provide steps for implementing the specified function.

[0154] While the principles herein have been illustrated in various embodiments, numerous modifications to the structure, arrangement, proportions, elements, materials, and components, particularly suited to specific environmental and operational requirements, may be used without departing from the principles and scope of this disclosure. These modifications and other alterations or alterations will be included within the scope of this document.

[0155] The foregoing specific descriptions have been described with reference to various embodiments. However, those skilled in the art will recognize that various modifications and changes can be made without departing from the scope of this disclosure. Therefore, considerations for this disclosure are to be illustrative rather than restrictive, and all such modifications are to be included within its scope. Similarly, advantages, other advantages, and solutions to problems with respect to various embodiments have been described above. However, benefits, advantages, solutions to problems, and any elements that produce these, or make them more explicit, should not be construed as critical, essential, or necessary. The term “comprising” and any other variations thereof as used herein are non-exclusive inclusion, meaning that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not expressly listed or not part of the process, method, system, article, or apparatus. Furthermore, the term “coupled” and any other variations thereof as used herein refer to physical connections, electrical connections, magnetic connections, optical connections, communication connections, functional connections, and / or any other connections.

[0156] Those skilled in the art will recognize that many changes can be made to the details of the above embodiments without departing from the basic principles of the invention. Therefore, the scope of the invention should be defined only by the following claims.

Claims

1. A respiratory ventilation device for animals, characterized in that, The respiratory ventilation device has an automatic trigger control mode, and the respiratory ventilation device includes: Gas source interface, used to connect to an external gas source; Anesthetic delivery device, used to provide a gas mixed with anesthetic drugs; A breathing circuit is used to connect the gas source interface to the animal's respiratory system, so as to input a preset gas into the animal and discharge some of the gas exhaled by the animal into the external environment; the preset gas is the gas provided by the external gas source and the gas mixed with anesthetic output by the anesthetic output device. A respiratory assist device is used to provide power to introduce the preset gas into the animal or to expel part of the gas exhaled by the animal into the external environment; A processor is configured to automatically adjust the trigger sensitivity of the respiratory ventilation device acting on the animal during ventilation in the automatic trigger control mode; wherein the processor acquires characteristic information corresponding to the animal and determines the target respiratory rate range of the animal based on the characteristic information corresponding to the animal, and in the automatic trigger control mode, the processor automatically adjusts the trigger sensitivity of the respiratory ventilation device acting on the animal during ventilation so that the monitored respiratory rate of the animal meets the requirements of the target respiratory rate range.

2. The respiratory ventilation device as described in claim 1, characterized in that, The animal-related characteristic information includes the animal's individual information and / or the numerical values ​​of the animal's ventilation parameters.

3. The respiratory ventilation device as described in claim 2, characterized in that, The values ​​of the ventilation parameters corresponding to the animal include the set values ​​or monitoring values ​​of the ventilation parameters corresponding to the animal.

4. The respiratory ventilation device as described in claim 2, characterized in that, The individual information of the animal includes one or more of the following: species, weight, age, and size.

5. The respiratory ventilation device as described in claim 2, characterized in that, The ventilation parameters include one or more of the following: tidal volume, gas flow rate, driving pressure, positive end-expiratory pressure, and respiratory ratio.

6. The respiratory ventilation device as described in claim 1, characterized in that, The trigger sensitivity includes inspiratory trigger value and / or expiratory trigger value.

7. The respiratory ventilation device as described in claim 1, characterized in that, The adjusted trigger sensitivity includes the sensitivity for flow rate triggering and / or the sensitivity for pressure triggering; wherein: Improving the current trigger sensitivity includes: reducing the trigger threshold corresponding to the sensitivity of flow rate triggering and / or the sensitivity of pressure triggering; Reducing the current trigger sensitivity includes increasing the trigger threshold corresponding to the sensitivity of flow rate triggering and / or pressure triggering.

8. The respiratory ventilation device as described in claim 7, characterized in that, The processor is also configured to calculate the sensitivity of pressure triggering based on the feature information and set it as the initial value of the triggering sensitivity of the breathing ventilation device.

9. A respiratory ventilation device for animals, characterized in that, The respiratory ventilation device includes: an air source interface, an anesthetic output device, a breathing circuit, a breathing assist device, an input component, a display, and a processor; The gas source interface is used to connect to an external gas source; the anesthetic output device is used to provide a gas mixed with anesthetic; the breathing circuit is used to connect the gas source interface to the animal's respiratory system to input a preset gas into the animal and discharge some of the gas exhaled by the animal into the external environment; the preset gas is a mixture of gas provided by the external gas source and gas output by the anesthetic output device; the breathing assist device is used to provide power to input the preset gas into the animal or discharge some of the gas exhaled by the animal into the external environment. The input component is used to receive the user's selection of a respiratory trigger mode, which includes at least an automatic trigger control mode. In the automatic trigger control mode, the processor automatically adjusts the trigger sensitivity applied to the animal during ventilation. The display is used to display one or more of the animal's monitored respiratory rate, the selected respiratory trigger mode, and the trigger sensitivity during ventilation. The processor acquires characteristic information corresponding to the animal and determines the target respiratory rate range for the animal based on this characteristic information. In the automatic trigger control mode, the processor automatically adjusts the trigger sensitivity of the ventilation device applied to the animal during ventilation to ensure that the animal's monitored respiratory rate meets the requirements of the target respiratory rate range.

10. The respiratory ventilation device as described in claim 9, characterized in that, The input component is also used to receive characteristic information corresponding to the animal input by the user.

11. The respiratory ventilation device as described in claim 10, characterized in that, The animal-related characteristic information includes the animal's individual information and / or the setting values ​​of the ventilation parameters corresponding to the animal.

12. The respiratory ventilation device as described in claim 11, characterized in that, The individual information of the animal includes one or more of the following: species, weight, age, and size.

13. The respiratory ventilation device as described in claim 11, characterized in that, The ventilation parameters include one or more of the following: tidal volume, gas flow rate, driving pressure, positive end-expiratory pressure, and respiratory ratio.

14. A smart triggering method for an animal respiratory ventilation device, characterized in that, include: To obtain the respiratory rate of animals during ventilation; After activating the automatic trigger control mode, the trigger sensitivity of the ventilation device applied to the animal during ventilation is automatically adjusted to regulate the animal's respiratory rate. Specifically, characteristic information corresponding to the animal is acquired, and the target respiratory rate range for the animal is determined based on this characteristic information. After activating the automatic trigger control mode, the trigger sensitivity of the ventilation device applied to the animal during ventilation is automatically adjusted to ensure that the animal's monitored respiratory rate meets the requirements of the target respiratory rate range.

15. A smart triggering method for an animal respiratory ventilation device, characterized in that, include: Receives the user's selection of a breathing trigger mode, wherein the breathing trigger mode includes at least an automatic trigger control mode; After the automatic trigger control mode is enabled, the trigger sensitivity of the ventilation device acting on the animal during ventilation is automatically adjusted. The display shows one or more of the animal's respiratory rate, the selected respiratory triggering mode, and the triggering sensitivity during ventilation. Obtain the characteristic information corresponding to the animal, and determine the target respiratory rate range of the animal based on the characteristic information corresponding to the animal; After the automatic trigger control mode is activated, the trigger sensitivity of the ventilation device acting on the animal during ventilation is automatically adjusted so that the animal's monitored respiratory rate meets the requirements of the target respiratory rate range.

Images