Sample analysis system and analyzer

Abstract

The embodiment of the present application discloses a sample analysis system and an analyzer. The sample analysis system comprises a detection structure, a solution supply structure, a diluent pool, a first liquid path, a second liquid path, a positive pressure structure and a double syringe. The detection structure comprises a WBC pool and an RBC pool. The first liquid path can be in communication with the solution supply structure, the diluent pool and the WBC pool. The second liquid path has a sample suction needle, and part of the structure of the second liquid path can connect the diluent pool and the back pool of the RBC pool. The positive pressure structure can provide positive pressure for the diluent pool. The double syringe comprises a first syringe and a second syringe. The first syringe is connected to the first liquid path, and the first syringe can be in communication with the solution supply structure, the diluent pool and the WBC pool respectively. The second syringe is connected to the second liquid path, and the second syringe can be in communication with the diluent pool and the sample suction needle respectively. Through the above arrangement, the WBC pool and the RBC pool can be cleaned at the same time, the cleaning time is reduced, and the analysis efficiency of sample analysis is increased.

Description

Technical Field

[0001] This invention relates to the field of analyzer technology, and more particularly to a sample analysis system and analyzer. Background Technology

[0002] Currently, the mainstream technical principle for three-part differential hematology is impedance analysis. Given its advantages such as simple control, reliability, and low cost, this technology is widely used in low- to mid-range hematology analysis products.

[0003] Current three-class sample analysis systems, due to their positioning in the low-end market, are limited by cost and capacity, resulting in severe resource constraints throughout the entire sample analysis process, including sample preparation, testing, and especially the cleaning of instrument components.

[0004] In related technologies, cleaning the sample needle and cleaning the front and rear chambers of the counting chamber both require a single syringe to be used sequentially, making it impossible to perform the cleaning work in parallel. As a result, the overall sample analysis speed is slowed down, leading to low sample analysis efficiency. Summary of the Invention

[0005] Therefore, it is necessary to propose a sample analysis system and analyzer to improve the sample analysis speed in order to address the above problems.

[0006] This invention provides a sample analysis system, comprising:

[0007] The detection structure includes a WBC pool and an RBC pool, wherein the rear pool of the RBC pool and the rear pool of the WBC pool are connected.

[0008] Solution supply structure for supplying hemolytic agents and diluents;

[0009] A diluent tank is provided for storing the diluent.

[0010] The first liquid path is connected to the solution supply structure, the diluent tank, and the WBC tank;

[0011] The second liquid path has a sampling needle, and part of the structure of the second liquid path can connect the diluent pool and the rear pool of the RBC pool;

[0012] A positive pressure structure is connected to the diluent tank and can provide positive pressure to the diluent tank to transport the liquid in the diluent tank to the downstream tank of the RBC tank;

[0013] And a dual syringe, including a first syringe and a second syringe, wherein the first syringe is connected to the first liquid path, so that the first syringe can be connected to the solution supply structure, the diluent pool and the WBC pool respectively;

[0014] The second syringe is connected to the second liquid path, so that the second syringe can communicate with the diluent pool and the sampling needle respectively.

[0015] In some embodiments, the first liquid circuit includes a first control valve, a second control valve, a third control valve, a fourth control valve, and a plurality of first pipelines. Two valve ports of the first control valve are respectively connected to the valve port of the second control valve and the solution supply structure through the first pipelines. The other valve port of the first control valve is connected to the first syringe. The third control valve and the fourth control valve are respectively connected to two valve ports of the second control valve. Two valve ports of the third control valve are respectively connected to the solution supply structure and the WBC pool through the first pipelines. One valve port of the fourth control valve is connected to the diluent pool.

[0016] In some embodiments, the second fluid path includes a fifth control valve, a sixth control valve, a seventh control valve, and a plurality of second lines. The fifth control valve, the sixth control valve, and the seventh control valve are sequentially connected through the second lines. The sampling needle is connected to one port of the fifth control valve, the other port of the fifth control valve is connected to the second syringe, one port of the sixth control valve is connected to the diluent pool, and the port of the seventh control valve is connected to the rear chamber of the RBC pool.

[0017] In some embodiments, the positive pressure structure includes a positive pressure chamber, an air pump, an eighth control valve, and a positive pressure sensor. The air pump is connected to the positive pressure chamber to provide positive pressure to the positive pressure chamber. One end of the eighth control valve is connected to the positive pressure chamber, and the other end is connected to the WBC pool and the RBC pool, respectively.

[0018] In some embodiments, a negative pressure structure is further included, which includes a negative pressure chamber, a liquid pump, a negative pressure sensor, a ninth control valve, a tenth control valve, and an eleventh control valve. The ninth control valve and the tenth control valve are respectively connected between the WBC pool and the negative pressure chamber, and between the RBC pool and the negative pressure chamber. The eleventh control valve is connected between the negative pressure chamber and the post-pool of the WBC. The liquid pump and the negative pressure sensor are both connected to the negative pressure chamber.

[0019] In some embodiments, the WBC pool has a first outlet and two first inlets, the RBC pool has a second outlet and two second inlets, the seventh control valve is connected to the second outlet, the two second inlets are connected to the first outlet, and the two first inlets are connected to the eleventh control valve.

[0020] In some embodiments, a swab is also included for cleaning the sampling needle, two openings of the swab being connected to the diluent pool and the negative pressure chamber, respectively, and a twelfth control valve is provided between the swab and the negative pressure chamber.

[0021] In some embodiments, the negative pressure structure further includes a waste liquid tank, which is connected to the negative pressure chamber via a liquid pump.

[0022] In some embodiments, the solution supply structure includes a hemolytic agent tank and a diluent tank.

[0023] This invention also provides an analyzer, including the sample analysis system described above.

[0024] The embodiments of the present invention have the following beneficial effects:

[0025] According to the sample analysis system and analyzer in the above embodiments, by setting up a first liquid path and a second liquid path, the first syringe can draw up the diluent from the solution supply structure and then inject the diluent into the WBC cell to clean the front chamber of the WBC cell. Since the first and second syringes are linked, the second syringe can simultaneously draw up the diluent from the solution supply structure through the sampling needle and then inject the diluent into the RBC cell through the sampling needle to clean the front chamber of the RBC cell. Furthermore, by setting up a diluent pool and a positive pressure structure, the positive pressure structure applies positive pressure to the diluent pool, transporting the diluent in the diluent pool to the rear chamber of the RBC cell. Since the rear chamber of the RBC cell is connected to the rear chamber of the WBC cell, both the rear chambers of the WBC cell and the rear chamber of the RBC cell can be cleaned. Therefore, through the above setup, the WBC cell and the RBC cell can be cleaned simultaneously, which reduces cleaning time and increases the analytical efficiency of sample analysis compared to the prior art of cleaning the WBC cell and RBC cell one by one. Attached Figure Description

[0026] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0027] in:

[0028] Figure 1 A schematic diagram of the sample analysis system provided according to the present invention is shown;

[0029] Figure 2 A schematic diagram of the connection structure between the WBC pool and the RBC pool provided according to the present invention is shown.

[0030] Explanation of key component symbols:

[0031] 1. Dual-syringe; 11. First syringe; 12. Second syringe; 2. First fluid path; 21. First control valve; 22. Second control valve; 23. Third control valve; 24. Fourth control valve; 25. First tubing; 3. Second fluid path; 31. Fifth control valve; 32. Sixth control valve; 33. Seventh control valve; 34. Sampling needle; 35. Second tubing; 4. Positive pressure structure; 41. Air pump; 42. Positive pressure chamber; 43. Eighth control valve; 44. Positive pressure sensor; 5. Negative pressure structure; 51. Ninth control valve; 52. Tenth control valve 53. Eleventh control valve; 54. Negative pressure sensor; 55. Negative pressure chamber; 56. Liquid pump; 57. Waste liquid tank; 6. Solution supply structure; 61. Diluent tank; 62. Hemolysin tank; 70. Swab; 8. Detection structure; 81. WBC tank; 810. WBC pre-tank; 811. WBC post-tank; 812. First outlet; 813. First liquid inlet; 82. RBC tank; 820. RBC pre-tank; 821. RBC post-tank; 822. Second outlet; 823. Second liquid inlet; 90. Twelfth control valve; 100. Diluent tank. Detailed Implementation

[0032] To facilitate understanding of the present invention, a more complete description will be given below with reference to the accompanying drawings. Preferred embodiments of the invention are shown in the drawings. However, the invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to provide a thorough and complete understanding of the disclosure of the invention.

[0033] It should be noted that when a component is said to be "fixed to" another component, it can be directly attached to the other component or there may be an intervening component. When a component is said to be "connected to" another component, it can be directly connected to the other component or there may be an intervening component. The terms "vertical," "horizontal," "left," "right," and similar expressions used in this document are for illustrative purposes only.

[0034] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0035] On one hand, the present invention provides a sample analysis system that can be applied in an analyzer to detect and analyze white blood cells, red blood cells, etc. In one embodiment, please refer to... Figure 1 The sample analysis system includes a detection structure 8, a solution supply structure 6, a dilution pool 100, a first liquid path 2, a second liquid path 3, a positive pressure structure 4, and a dual-syringe 1.

[0036] The detection structure 8 can detect not only white blood cells and red blood cells, but also platelets and hemoglobin. In this embodiment, the detection structure 8 mainly includes a WBC pool 81 and an RBC pool 82, which detect white blood cells and red blood cells respectively. In this embodiment, the rear pool of the RBC pool 82 and the rear pool of the WBC pool 81 are connected.

[0037] The solution supply structure 6 is used to supply solutions for reaction or cleaning. For example, the solution supply structure 6 in the embodiments of this application is mainly used to supply hemolytic agents and diluents.

[0038] The diluent pool 100 is capable of storing diluent. The diluent pool 100 is different from the solution supply structure 6, but the diluent in the solution supply structure 6 can be injected into the diluent pool 100 by the dual syringe 1 described below.

[0039] The first liquid path 2 has multiple ports, some of which can be connected to the solution supply structure 6, the diluent pool 100, and the WBC pool 81.

[0040] The second liquid path 3 also has multiple ports, one of which is connected to a sampling needle 34. Part of the structure of the second liquid path 3 can connect the diluent pool 100 and the rear pool of the RBC pool 82.

[0041] The positive pressure structure 4 is connected to the diluent tank 100. The positive pressure structure 4 can generate a predetermined pressure and provide positive pressure to the diluent tank 100 to force the liquid in the diluent tank 100 out of the diluent tank 100 and transport the diluent to the rear tank of the RBC tank 82 through the second liquid passage 3.

[0042] The dual-syringe 1 includes a first syringe 11 and a second syringe 12. The pistons of the first syringe 11 and the second syringe 12 are connected by the same fixing member, so that pushing one piston can move the other piston at the same time, realizing the linkage of the pistons of the two syringes. Therefore, the structure of the first syringe 11 and the second syringe 12 is the structure of the dual-syringe 1.

[0043] It should be noted that the injection port of the first syringe 11 is connected to one of the ports of the first liquid path 2, and the ports of the first liquid path 2 are connected to each other, so that the first syringe 11 can be connected to the solution supply structure 6, the diluent pool 100 and the WBC pool 81 respectively. In this way, when the piston of the first syringe 11 is pulled, liquid can be drawn from other structures through the first liquid path 2, and the liquid inside the first syringe 11 can be injected into the external structure by pushing the piston.

[0044] The injection port of the second syringe 12 is connected to one port of the second liquid passage 3. The ports of the second liquid passage 3 are interconnected, allowing the second syringe 12 to be connected to the diluent pool 100 and the sampling needle 34 respectively. When the second syringe 12 is connected to the sampling needle 34, liquid can be drawn into the second syringe 12 through the sampling needle 34, and liquid in the second syringe 12 can also be injected into the corresponding structure through the sampling needle 34.

[0045] By setting up a first liquid path 2 and a second liquid path 3, the first syringe 11 can draw up the diluent from the solution supply structure 6 and then inject the diluent into the WBC pool 81 to clean the front pool of the WBC pool 81. Since the first syringe 11 and the second syringe 12 are linked, the second syringe 12 can simultaneously draw up the diluent from the solution supply structure 6 through the sampling needle 34 and then inject the diluent into the RBC pool 82 through the sampling needle 34 to clean the front pool of the RBC pool 82. Furthermore, by setting up a diluent pool 100 and a positive pressure structure 4, the positive pressure structure 4 applies positive pressure to the diluent pool 100, which can transport the diluent in the diluent pool 100 to the rear pool of the RBC pool 82. Since the rear pool of the RBC pool 82 is connected to the rear pool of the WBC pool 81, the rear pools of both the WBC pool 81 and the RBC pool 82 can be cleaned. Therefore, with the above settings, the WBC pool 81 and RBC pool 82 can be cleaned simultaneously. Compared with the prior art which cleans WBC pool 81 and RBC pool 82 one by one, the solution of this application can reduce the cleaning time and increase the analysis efficiency of sample analysis.

[0046] In one embodiment, please refer to Figure 1 The first liquid circuit 2 includes a first control valve 21, a second control valve 22, a third control valve 23, a fourth control valve 24, and a plurality of first pipelines 25. The structures of the first liquid circuit 2 are connected to each other through the first pipelines 25, and the first liquid circuit 2 is also connected to other structures through the first pipelines 25.

[0047] Specifically, the first control valve 21, the second control valve 22, the third control valve 23, and the fourth control valve 24 are preferably two-position three-way control valves. Each control valve has three main valve ports: one inlet and two outlets. The inlet can be connected to two outlets respectively. When the inlet is connected to one outlet, it is not connected to the other outlet. For the specific structure, please refer to the structure of the two-position three-way control valve in the prior art, which will not be described here.

[0048] It should be noted that the two outlets of the first control valve 21 are connected to the inlet of the second control valve 22 and the solution supply structure 6 respectively through the first pipeline 25. The inlet of the first control valve 21 is connected to the outlet of the first syringe 11. In this way, by controlling the first control valve 21, the inlet of the first control valve 21 can be connected to either the inlet or the two outlets, thereby connecting the first syringe 11 to the second control valve 22 or to the solution supply structure 6.

[0049] The inlets of the third control valve 23 and the fourth control valve 24 are connected to the two outlets of the second control valve 22 via the first pipe 25, respectively. That is to say, by controlling the second control valve 22, the first syringe 11 can be connected to the third control valve 23 or the fourth control valve 24. The two outlets of the third control valve 23 are connected to the solution supply structure 6 and the WBC pool 81 via the first pipe 25, respectively. One outlet of the fourth control valve 24 is connected to the diluent pool 100 via the first pipe 25.

[0050] The operation achievable through the first liquid path 2 described above is as follows: If the first control valve 21 is controlled to connect the first syringe 11 and the solution supply structure 6, pulling the piston of the first syringe 11 will draw the hemolytic agent or diluent from the solution supply structure 6. When it is necessary to output the liquid inside the first syringe 11, the first control valve 21 can be controlled to connect the first syringe 11 to the second control valve 22. The second control valve 22 has two outlets: one can lead to the WBC pool 81 through the third control valve 23, and the other can lead to the diluent pool 100 through the fourth control valve 24. To input the liquid from the first syringe 11 into a specific structure, the inlet of the second control valve 22 can be connected to the outlet of the corresponding structure. For example, if the first syringe 11 draws diluent from the solution supply structure 6 and you want to output the diluent to the diluent pool 100 for storage, you need to control the first control valve 21 and the second control valve 22 to connect, then control the second control valve 22 to connect with the fourth control valve 24, control the inlet of the fourth control valve 24 to connect with the outlet connected to the diluent pool 100, and then push the piston of the first syringe 11 to deliver the diluent to the diluent pool 100.

[0051] It should be noted that one outlet of both the first control valve 21 and the third control valve 23 is connected to the solution supply structure 6. This is to enable the aspiration of different solutions from the first syringe 11. Because the solution supply structure 6 can provide different solutions (hemolysin and diluent), and different solutions are stored separately in different structures, two different ports are needed to connect to the structures containing different solutions, thereby enabling the separate aspiration of different solutions.

[0052] In one embodiment, please refer to Figure 1 The second liquid circuit 3 includes a fifth control valve 31, a sixth control valve 32, a seventh control valve 33, and multiple second pipelines 35. All structures within the second liquid circuit 3 are connected via the second pipelines 35, and the second liquid circuit 3 is also connected to other structures via the second pipelines 35. The fifth control valve 31, the sixth control valve 32, and the seventh control valve 33 can be sequentially connected via the second pipelines 35. It should be noted that in this embodiment, the fifth control valve 31 is preferably a two-position three-way valve, and the sixth control valve 32 and the seventh control valve 33 are preferably two-position two-way control valves. As mentioned above, the two-position three-way fifth control valve 31 has one inlet and two outlets, while the two-position two-way control valve has one inlet and one outlet, allowing for the connection and closure of the inlet and outlet through control.

[0053] The outlet of the second syringe 12 is connected to the inlet of the fifth control valve 31 via the second conduit 35. The sampling needle 34 is connected to one outlet of the fifth control valve 31 via the second conduit 35. The outlet of the sixth control valve 32 is connected to the diluent reservoir 100, and the inlet is connected to the other outlet of the fifth control valve 31 via the second conduit 35. The outlet of the seventh control valve 33 is connected to the rear chamber of the RBC reservoir 82 via the second conduit 35.

[0054] It is worth mentioning that the inlet of the seventh control valve 33 can also be connected to the outlet of the sixth control valve 32. This requires a connector structure; in this embodiment, a three-way connector is used to connect the outlet of the sixth control valve 32, the diluent pool 100, and the inlet of the seventh control valve 33 through the second pipeline 35. In this way, the second syringe 12 can draw diluent from the diluent pool 100. When the inlet and outlet of the sixth control valve 32 are disconnected and the inlet and outlet of the seventh control valve 33 are connected, the positive pressure structure 4 can drive the diluent in the diluent pool 100 into the rear chamber of the RBC pool 82.

[0055] The second liquid path 3 described above allows for the following operations: When the fifth control valve 31 is controlled to connect the second syringe 12 and the sampling needle 34, pulling the piston of the second syringe 12 allows the solution to be drawn through the sampling needle 34 and into the second syringe 12. During sample addition, the second syringe 12 can be pushed to add the solution into the corresponding structure through the sampling needle 34. When it is necessary to draw diluent from the diluent pool 100, the fifth control valve 31 can be controlled to connect the second syringe 12 to the sixth control valve 32. Simultaneously, the sixth control valve 32 opens, and pulling the second syringe 12 draws diluent from the diluent pool 100. If it is desired to input the diluent from the diluent pool 100 into the RBC pool 82, as mentioned above, the sixth control valve 32 is closed, and the seventh control valve 33 is opened. The positive pressure of the positive pressure structure 4 then drives the diluent from the diluent pool 100 to be transported into the RBC pool 82.

[0056] In one embodiment, please refer to Figure 1 The positive pressure structure 4 includes a positive pressure chamber 42, an air pump 41, an eighth control valve 43, and a positive pressure sensor 44. The air pump 41 is connected to an opening in the positive pressure chamber 42 to provide a power source for establishing positive pressure in the positive pressure chamber 42. The positive pressure sensor 44 is connected to the interior of the positive pressure chamber 42 to measure the pressure inside the positive pressure chamber 42. If the pressure exceeds a predetermined pressure, pressure needs to be released; if the pressure is less than the predetermined pressure, pressure needs to be replenished. One outlet of the positive pressure chamber 42 is connected to the diluent pool 100 through an air pipe, so that the positive pressure generated by the positive pressure chamber 42 can be delivered to the diluent pool 100.

[0057] The eighth control valve 43 is preferably a two-position, two-way valve. Its inlet is connected to the positive pressure chamber 42 via a pipeline, and its outlet is connected to the pre-pool of WBC pool 81 and the pre-pool of RBC pool 82 via a tee connector. The solutions input to WBC pool 81 and RBC pool 82 are generally injected into the pre-pools of WBC pool 81 and RBC pool 82. By opening the eighth control valve 43, positive pressure is supplied to WBC pool 81 and RBC pool 82 using the positive pressure chamber 42, which can mix the solutions in WBC pool 81 and RBC pool 82.

[0058] In one embodiment, the analysis system further includes a negative pressure structure 5, which includes a negative pressure chamber 55, a liquid pump 56, a negative pressure sensor 54, a ninth control valve 51, a tenth control valve 52, and an eleventh control valve 53. The liquid pump 56 is connected to the negative pressure chamber 55 to establish a negative pressure in the chamber, and the negative pressure sensor 54 is connected to the chamber to detect the pressure inside the chamber and determine whether the pressure inside the chamber meets the preset negative pressure.

[0059] The ninth control valve 51 and the tenth control valve 52 are preferably two-position two-way valves, or the ninth control valve 51 and the tenth control valve 52 can be two-position three-way valves. The ninth control valve 51 is connected between the forepool and the negative pressure chamber 55 of the WBC pool 81 through a pipeline, and the tenth control valve 52 is connected between the forepool and the negative pressure chamber 55 of the RBC pool 82 through a pipeline. When the ninth control valve 51 and the tenth control valve 52 are opened, the negative pressure of the negative pressure chamber 55 can empty the WBC pool 81 and the RBC pool 82.

[0060] The eleventh control valve 53 is connected between the negative pressure chamber 55 and the rear chamber of the WBC, and can control the measurement of the sample solution.

[0061] Specifically, please refer to Figure 1 and Figure 2 The WBC pool 81 has a WBC pre-pool 810 and a WBC post-pool 811, and the RBC pool 82 has an RBC pre-pool 820 and an RBC post-pool 821. The WBC post-pool 811 and the WBC pre-pool 810 are connected. The WBC post-pool 811 has a first outlet 812 and two first liquid inlets 813. The RBC post-pool 821 has a second outlet 822 and two second liquid inlets 823. The seventh control valve 33 is connected to the second outlet 822 through a second pipeline 35.

[0062] The two second liquid ports 823 and the first outlet 812 are connected by three pipes and a tee connector. The two first liquid ports 813 are also connected to the inlet of the eleventh control valve 53 via three pipes and a tee connector. The outlet of the eleventh control valve 53 is connected to the negative pressure chamber 55. When measurement is required, the eleventh control valve 53 is opened. The negative pressure in the negative pressure chamber 55 creates suction for the WBC post-pool 811, drawing the sample solution from the WBC pre-pool 810 into the WBC post-pool 811, thus achieving counting measurement. Because the WBC post-pool 811 is connected to the two second liquid ports 823 of the RBC post-pool 821 via the first outlet 812, when the negative pressure chamber 55 provides negative pressure to the WBC post-pool 811, it also provides negative pressure to the RBC post-pool 821, thereby drawing the sample solution from the RBC pre-pool 820 into the RBC post-pool 821, thus achieving counting measurement.

[0063] When it is necessary to clean the RBC post-pool 821 and WBC post-pool 811, the positive pressure of the positive pressure chamber 42 drives the diluent inside the diluent pool 100 to enter the RBC post-pool 821 to clean it. The diluent can also enter the WBC post-pool 811 through the second liquid port 823 of the RBC post-pool 821 to clean the WBC post-pool 811.

[0064] It is worth mentioning that the negative pressure structure 5 also includes a waste liquid tank 57, which is connected to the negative pressure chamber 55 via a liquid pump 56. Waste liquid drawn in by the liquid pump 56 can flow into the waste liquid tank 57, thereby achieving waste liquid collection.

[0065] In one embodiment, the analysis system further includes a swab 70 capable of cleaning the outer wall of the sample needle. Specifically, one port of the swab 70 is connected to the inlet of the sixth control valve 32. Since the inlet of the sixth control valve 32 is connected to the fifth control valve 31, a tee connector is also required here to connect the outlet of the fifth control valve 31, the port of the swab 70, and the inlet of the sixth control valve 32. The sampling needle 34 can be inserted into the swab 70, with its port connected to the interior of the swab 70. When the sixth control valve 32 is opened, and driven by the positive pressure in the positive pressure chamber 42, the diluent in the diluent pool 100 can be driven into the swab 70 to rinse the outer wall of the sampling needle 34.

[0066] The swab 70 also has another port that is connected to the interior of the swab 70. This port is connected to a twelfth control valve 90 via a pipeline. The twelfth control valve 90 is a two-position two-way valve. The other opening of the twelfth control valve 90 is connected to a negative pressure chamber 55 via a pipeline. Through the negative pressure of the negative pressure chamber 55, the waste liquid after cleaning the outer wall of the sampling needle 34 inside the swab 70 can be drawn out of the swab 70.

[0067] Additionally, another outlet of the fourth control valve 24 can be connected to the second syringe 12 via the first conduit 25. This allows the first control valve 21 and the second control valve 22 to be connected when the first syringe 11 contains diluent, simultaneously connecting the second control valve 22 and the fourth control valve 24, thus connecting the first syringe 11 and the second syringe 12. Controlling the fifth control valve 31 connects the second syringe 12 and the sampling needle 34. Pushing the second syringe 12 then delivers the diluent from the first syringe 11 into the second syringe 12. The diluent can then be injected into the sampling needle 34 to clean its inner wall. Combined with the aforementioned swab 70 to clean the outer wall of the sampling needle 34, simultaneous cleaning of both the inner and outer walls of the sampling needle 34 can be achieved, thereby reducing the overall system detection and cleaning time and increasing detection efficiency.

[0068] In one embodiment, the solution supply structure 6 mentioned above mainly includes a hemolysin tank 62 and a diluent tank. The hemolysin tank 62 is used to store the hemolysin, and the diluent tank is used to store the diluent.

[0069] On the other hand, the present invention also provides an analyzer that includes the sample analysis system described above.

[0070] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0071] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the scope of protection of the present invention. Therefore, the scope of protection of this patent should be determined by the appended claims.

Claims

1. A sample analysis system, characterized in that, include: The detection structure includes a WBC pool and an RBC pool, wherein the rear pool of the RBC pool and the rear pool of the WBC pool are connected. Solution supply structure for supplying hemolytic agents and diluents; A diluent tank is provided for storing the diluent. The first liquid path is connected to the solution supply structure, the diluent tank, and the WBC tank; The second liquid path has a sampling needle, and part of the structure of the second liquid path can connect the diluent pool and the rear pool of the RBC pool; A positive pressure structure is connected to the diluent tank and can provide positive pressure to the diluent tank to transport the liquid in the diluent tank to the downstream tank of the RBC tank; And a dual syringe, including a first syringe and a second syringe, wherein the first syringe is connected to the first liquid path, so that the first syringe can be connected to the solution supply structure, the diluent pool and the WBC pool respectively; The second syringe is connected to the second liquid path, so that the second syringe can communicate with the diluent pool and the sampling needle respectively.

2. The sample analysis system according to claim 1, characterized in that, The first liquid circuit includes a first control valve, a second control valve, a third control valve, a fourth control valve, and a plurality of first pipelines. Two of the valve ports of the first control valve are connected to the valve port of the second control valve and the solution supply structure respectively through the first pipelines. The other valve port of the first control valve is connected to the first syringe. The third control valve and the fourth control valve are respectively connected to two valve ports of the second control valve. Two of the valve ports of the third control valve are connected to the solution supply structure and the WBC pool respectively through the first pipelines. One valve port of the fourth control valve is connected to the diluent pool.

3. The sample analysis system according to claim 1, characterized in that, The second liquid circuit includes a fifth control valve, a sixth control valve, a seventh control valve, and multiple second pipelines. The fifth control valve, the sixth control valve, and the seventh control valve can be connected sequentially through the second pipelines. The sampling needle is connected to one valve port of the fifth control valve, the other valve port of the fifth control valve is connected to the second syringe, one valve port of the sixth control valve is connected to the diluent pool, and the valve port of the seventh control valve is connected to the rear pool of the RBC pool.

4. The sample analysis system according to any one of claims 1-3, characterized in that, The positive pressure structure includes a positive pressure chamber, an air pump, an eighth control valve, and a positive pressure sensor. The air pump is connected to the positive pressure chamber to provide positive pressure to the positive pressure chamber. One end of the eighth control valve is connected to the positive pressure chamber, and the other end is connected to the WBC pool and the RBC pool, respectively.

5. The sample analysis system according to claim 3, characterized in that, It also includes a negative pressure structure, which includes a negative pressure chamber, a liquid pump, a negative pressure sensor, a ninth control valve, a tenth control valve, and an eleventh control valve. The ninth and tenth control valves are respectively connected between the WBC pool and the negative pressure chamber, and between the RBC pool and the negative pressure chamber. The eleventh control valve is connected between the negative pressure chamber and the rear pool of the WBC. The liquid pump and the negative pressure sensor are both connected to the negative pressure chamber.

6. The sample analysis system according to claim 5, characterized in that, The WBC pool has a first outlet and two first liquid inlets, the RBC pool has a second outlet and two second liquid inlets, the seventh control valve is connected to the second outlet, the two second liquid inlets are connected to the first outlet, and the two first liquid inlets are connected to the eleventh control valve.

7. The sample analysis system according to claim 5, characterized in that, It also includes a swab for cleaning the sampling needle, with two openings of the swab connected to the diluent pool and the negative pressure chamber, respectively, and a twelfth control valve provided between the swab and the negative pressure chamber.

8. The sample analysis system according to claim 5, characterized in that, The negative pressure structure also includes a waste liquid tank, which is connected to the negative pressure chamber via a liquid pump.

9. The sample analysis system according to claim 1, characterized in that, The solution supply structure includes a hemolytic agent tank and a diluent tank.

10. An analyzer, characterized in that, Includes the sample analysis system as described in any one of claims 1-9.

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