检测黄曲霉毒素M1的量子点荧光猝灭免疫分析方法
By using silanized Prussian blue nanozyme catalysis and quantum dot fluorescence quenching technology, aflatoxin M1 was detected with high sensitivity and stability, solving the problems of time-consuming detection and expensive equipment in existing technologies, and improving detection efficiency and accuracy.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- HEBEI UNIV OF SCI & TECH
- Filing Date
- 2023-07-18
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies for detecting aflatoxin M1 suffer from time-consuming processes, expensive equipment, and insufficient sensitivity. In particular, the enzyme-linked immunosorbent assay (ELISA) has a low signal-to-noise ratio, which limits its widespread application in food safety testing.
A primary signal amplification effect was generated by silanized Prussian blue nanozymes (PBNPs), and a secondary signal amplification was generated by quantum dot fluorescence quenching. A fluorescence immunoassay technique based on quantum dot fluorescence quenching was constructed, which combines enzymatic reaction and fluorescence signal reading to achieve dual signal amplification.
It improves detection sensitivity and stability, reduces detection costs, enhances the signal-to-noise ratio in complex biological environments, overcomes the limitations of traditional ELISA, and achieves rapid detection with high sensitivity and high accuracy.
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Abstract
Citation Information
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