Preparation of microphase-separated chiral nanofilms with tunable interlayer spacing

Abstract

The application discloses preparation of micro-phase separation chiral nanofilm with adjustable layer spacing and relates to the field of nanofilm materials. A series of amphiphilic molecules are synthesized first, and a series of liquid crystal block copolymers with different polymerization degrees are prepared by using a RAFT polymerization reaction. Micro-phase separation chiral nanofilm materials are successfully prepared by a limited gradient dialysis assembly method. The mutual stacking degree of the two in the cooperative self-assembly process is improved by using the amphiphilic molecules as an adjusting agent. The morphology and size of the film materials are precisely controlled by changing an assembly formula.

Description

Technical Field

[0001] This invention relates to the field of nanofilm materials, specifically to the preparation of microphase-separated chiral nanofilms with adjustable interlayer spacing. Background Technology

[0002] In recent years, the integrated circuit industry has developed rapidly, and semiconductor manufacturing processes have become increasingly sophisticated. Currently, a major challenge in manufacturing ultra-high-density devices in the semiconductor industry is reducing feature size. To address this issue, researchers have developed extreme ultraviolet lithography (EUVL), which can reduce pattern resolution to 13 nm, but its operating cost is high. Liquid crystal block copolymers, as a low-cost material, possess the ability to self-assemble into microphase-separated ordered nanostructures. Introducing liquid crystal segments into block copolymers can enhance the incompatibility between two blocks, providing additional conformational entropy, thereby generating strong separation domains and smaller nanostructures, demonstrating significant application value in fields such as nanolithography and high-density storage media. Therefore, the microphase-separated ordered structures formed by the self-assembly of liquid crystal block copolymers have become a hot topic of research and attention.

[0003] It has been reported that many types of liquid crystal block copolymers can form microphase-separated ordered structures, such as azobenzene, biphenyl, and fluorinated liquid crystals. Among them, fluorinated liquid crystal block copolymers have a significant advantage in reducing the characteristic size of ordered structures due to the strong thermodynamic incompatibility between the fluorinated segments and other polar and nonpolar segments. Currently, the size of microphase-separated assemblies formed from single polymer components is relatively fixed, which is not conducive to structural control and makes it impossible to obtain assemblies of the required size. Moreover, the assembly process is slow, and it is difficult to simultaneously combine functional properties. Summary of the Invention

[0004] To address the problems of existing technologies, the present invention aims to overcome the shortcomings of existing technologies by providing a method for preparing amphiphilic molecules and a method for preparing fluorinated liquid crystal block copolymers. Based on this, the two corresponding products are assembled by a restricted gradient dialysis method to prepare amphiphilic molecules and liquid crystal block copolymer nanofilms, achieving precise control of the morphology and size of such nanofilm materials. Furthermore, in this method, the amphiphilic molecules act as a regulator to improve the degree of mutual stacking during the synergistic self-assembly process, making it easier to control the chiral nanofilms.

[0005] One of the objectives of this invention is to provide an amphiphilic molecule, the specific technical solution of which is as follows: An amphiphilic molecule having a hydrophilic portion, a hydrophobic portion, and an intermediate linking unit between the hydrophilic portion and the hydrophobic portion, wherein the hydrophilic portion is a linear polyethylene glycol group, the hydrophobic portion is a fluorinated liquid crystal chain group, and the intermediate linking unit is directly linked by an ester bond or linked by a chiral group.

[0006] The second objective of this invention is to provide a synthetic formulation for amphiphilic molecules, the specific technical solution of which is as follows: The formulation for the synthesis of amphiphilic molecules includes linear polyethylene glycol with carboxyl groups at the end and organic materials containing fluorinated liquid crystal chains with hydroxyl groups.

[0007] Preferably, the formulation for synthesizing the amphiphilic molecule also includes an organic compound containing a chiral group.

[0008] The third objective of this invention is to provide a fluorinated liquid crystal block copolymer, the specific technical solution of which is as follows: A fluorinated liquid crystal block copolymer is a structure composed of monomers linked at both ends, wherein 2-vinylpyridine is the first monomer and a fluorinated liquid crystal chain homologous to the amphiphile is the second monomer.

[0009] The fourth objective of this invention is to provide a method for synthesizing fluorinated liquid crystal block copolymers, the specific technical solution of which is as follows: A method for synthesizing a fluorinated liquid crystal block copolymer includes the following two steps: S21. Under a protective atmosphere, 2-VP, RAFT reagent and initiator are dissolved in dioxane. After dehydration and deoxygenation, the solution is placed in a constant temperature environment for the first constant temperature stirring. Then, the solvent is removed by rotary evaporation. Finally, the first precipitation purification is performed to obtain the macromolecular initiator. S22. The macromolecular initiator, initiator and FMA are dissolved in dioxane, and after dehydration and deoxygenation treatment, they are placed in a constant temperature environment for a second constant temperature stirring, and then the solvent is removed by rotary evaporation. Finally, a second precipitation purification is performed to obtain the fluorinated liquid crystal block copolymer.

[0010] The fifth objective of this invention is to provide a method for preparing microphase-separated nanofilm materials, the specific technical solution of which is as follows: A method for preparing a microphase-separated nanofilm material includes the following three steps: S31. Dissolve the amphiphilic molecule and the fluorinated liquid crystal block copolymer in the initial solvent, and let stand until fully dissolved to obtain the initial solution; S32. Place the initial solution at a preset temperature and add deionized water dropwise to obtain a diluted solution; S33. The diluted solution is subjected to gradient dialysis to retain a molecular weight cutoff of 3500 Da, thereby obtaining an aqueous solution of microphase-separated nanofilm material.

[0011] Preferably, the molar ratio of the amphiphilic molecule to the fluorinated liquid crystal block copolymer is 1 to 5:1, and the initial solvent is THF, which is used to prepare a mixture with a concentration of 0.5 mg / mL of the fluorinated liquid crystal block copolymer.

[0012] Preferably, the preset temperature is 35°C.

[0013] Preferably, the volume of the deionized water is the same as the volume of the initial solvent.

[0014] The sixth objective of this invention is to provide a method for preparing microphase-separated chiral nanofilm materials, the specific technical solution of which is as follows: A method for preparing a microphase-separated chiral nanofilm material, characterized in that the reactants include the amphiphilic molecule as described in claim 1 and the fluorinated liquid crystal block copolymer as described in claim 4, wherein the intermediate linking unit of the amphiphilic molecule is a chiral group linking unit, and the method for preparing the microphase-separated chiral nanofilm material includes the following three steps: S31. Dissolve the amphiphilic molecule and the fluorinated liquid crystal block copolymer in an initial solvent, and let stand until fully dissolved to obtain an initial solution; S32. Place the initial solution at a preset temperature and add deionized water dropwise to obtain a diluted solution; S33. The diluted solution is subjected to gradient dialysis to retain a molecular weight cutoff of 3500 Da, thereby obtaining an aqueous solution of microphase-separated nanofilm material.

[0015] Compared with the prior art, the beneficial effects of the present invention are: This invention provides a method for preparing amphiphilic molecules by directly linking polyethylene glycol with benzoic acid as the end group and perfluorooctyl ethanol through ester bonds or by introducing alanine as a bridge. It also provides a method for preparing fluorinated liquid crystal block copolymers by RAFT polymerization of 2-vinylpyridine and perfluorooctyl acrylate (FMA), laying the foundation for preparing chiral nanofilms with adjustable interlayer spacing.

[0016] This invention constructs a microphase-separated fibrous ribbon nanofilm material by assembling amphiphilic molecules and fluorinated liquid crystal block copolymers through a restricted gradient dialysis method. The block copolymer structure has certain similarities with the amphiphilic molecules. The amphiphilic molecules act as regulators to improve the degree of mutual stacking of the two in the synergistic self-assembly process, making it easy to control the morphology of the polymer assembly. Currently, the interlayer spacing of the nanofilm material can be controlled down to 7 nm, and there is still some room for further down-tuning.

[0017] The microphase-separated fiber-ribbon nanofilm material prepared by this invention contains chiral amphiphilic molecules with amino acid structures that are chiral. By doping chiral features into non-chiral block copolymers, not only are chiral features introduced into the nanofilm material, but a chiral amplification effect is also produced. This material has the advantages of large molecular weight, good stability, and easy control of assembly structure.

[0018] This invention provides a method for preparing chiral nanofilms with adjustable interlayer spacing and microphase separation. This method develops and optimizes the preparation of chiral nanofilms with specific chemical structures, adjustable sizes and morphologies, and has great application potential in fields such as nanolithography, high-efficiency storage media, and chiral recognition materials. Attached Figure Description

[0019] Figure 1 The amphiphilic PEG molecule prepared in Example 1 of this invention n -F 1 H NMR spectrum; Figure 2 The amphiphilic PEG molecule prepared in Example 2 of this invention n -Ala-F 1 H NMR spectrum; Figure 3 The P2VP prepared in Example 3 of this invention 40 -PFMA 15 of 1 H NMR spectrum; Figure 4 The figures shown are circular dichroism (CD) chromatograms of the amphiphilic molecules prepared in Examples 1 and 2 of this invention. Figure 4 (A) shows the CD spectra of molecules from different parents. Figure 4 (B) shows the ultraviolet absorption spectra of different amphiphilic molecules; Figure 5 These are the circular dichroism (CD) chromatograms corresponding to the products of Examples 2 to 4 of this invention; Figure 6 These are transmission electron microscope images of the products of Examples 3 to 6 of the present invention, where (A) to (D) correspond to Examples 3 to 6, respectively. Detailed Implementation

[0020] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0021] To facilitate understanding, the abbreviations or nouns mentioned below will be explained first: DMAP: 4-Dimethylaminopyridine; DCM: Dichloromethane; PEG n Polyethylene glycol, where n is the degree of polymerization; Benzoic acid-terminated polyethylene glycol: The structural formula is: , which is a linear polyethylene glycol, where n is the degree of polymerization; EDC: 1-Ethyl-(3-dimethylaminopropyl)carbodiimide; TFA: Trifluoroacetic acid; Ala: alanine group; 2-VP: 2-Vinylpyridine; HOBT: Hydroxybenzotriazole; EDC: 1-Ethyl-(3-dimethylaminopropyl)carbodiimide; Furan-CTA: 4-cyano-4-(thiobenzoyl)-methylfuranoyl; AIBN: Azobisisobutyronitrile; FMA: Ethyl perfluorooctyl acrylate; THF: Tetrahydrofuran; Liquid nitrogen freezing: This is a highly efficient solvent degassing method. Generally, the solution is placed in a Schlenk flask, frozen into a solid, then a vacuum pump is used to create a vacuum, the vacuum system is then turned off, and an inert gas is introduced to slowly heat the solution to melt it. TEM: Transmission electron microscope; RAFT reagents: Reversible addition-fragmentation chain transfer reagents, such as the chain transfer reagent Furan-CTA, are used in RAFT polymerization reactions.

[0022] First, this specific embodiment provides a method for preparing an amphiphilic molecule. The synthetic formulation includes: an organic material with a carboxyl-containing linear polyethylene glycol end group and a fluorinated liquid crystal chain containing a hydroxyl group, wherein the carboxyl group of the former and the hydroxyl group of the latter are directly linked or linked through a chiral group to prepare an amphiphilic molecule having a hydrophilic part, a hydrophobic part, and an intermediate linking unit between the hydrophilic part and the hydrophobic part. The hydrophilic part is a linear polyethylene glycol group, the hydrophobic part is a fluorinated liquid crystal chain group, and the intermediate linking unit is directly linked by an ester bond (described in detail in Example 1) or linked by a chiral group (described in detail in Example 2).

[0023] Example 1: This embodiment describes a method for synthesizing amphiphilic molecules with intermediate linking units directly linked by ester bonds.

[0024] In this embodiment, the carboxyl-containing linear polyethylene glycol is selected from polyethylene glycol with carboxyl-terminal groups (n=15 in this embodiment), and the organic material containing hydroxyl-containing fluorinated liquid crystal chains is selected from perfluorooctylethanol.

[0025] The synthesis of amphiphilic molecules involves the following two steps: First, under a protective atmosphere, 2.24 mmol of carboxyl-terminated polyethylene glycol, 2.68 mmol of perfluorooctyl ethanol, 2.70 mmol of DMAP and 50 mL of dry DCM were mixed and stirred for 0.5 h to ensure that the liquid was fully mixed and homogeneous, thus obtaining a mixed solution. In the second step, under a protective atmosphere and ice bath conditions, 2.68 mmol of EDC was added to the mixed solution for a limited time, followed by stirring at room temperature for 12 hours to ensure complete reaction. The reaction solution was then removed by rotary evaporation to remove excess solvent, and purified by column chromatography to finally obtain a white solid PEG. n -F , where X= n=15.

[0026] X= This illustrates the direct linkage between the carboxyl group in polyethylene glycol with a carboxyl end and the hydroxyl group in perfluorooctyl ethanol. Therefore, the amphiphilic molecule prepared in this embodiment can also be called a linear amphiphilic molecule.

[0027] By selecting polyethylene glycols with different degrees of polymerization and carboxyl end groups, PEGs with different degrees of polymerization can be obtained. n -F, preferably n=10~50.

[0028] In this embodiment, nitrogen is used as the protective atmosphere.

[0029] In this embodiment, the time limit for the ice bath is 1 hour.

[0030] Example 2: This embodiment describes a method for synthesizing amphiphilic molecules with alanine groups as the intermediate linking unit, as detailed below: In this embodiment, the carboxyl-containing linear polyethylene glycol is selected from polyethylene glycol with benzoic acid as the terminal group, and the organic material containing hydroxyl-containing fluorinated liquid crystal chains is selected from perfluorooctylethanol.

[0031] The synthesis of amphiphilic molecules involves the following three steps: First, under a protective atmosphere, 3.23 mmol of perfluorooctyl ethanol, 5.17 mmol of tert-butyloxycarbonyl-protected L-alanine, 1.24 mmol of DMAP and 50 mL of dry DCM were mixed and stirred for 0.5 h to ensure that the liquid was fully mixed and homogeneous, thus obtaining a mixed solution. In the second step, under a protective atmosphere and in an ice bath, 6.20 mmol of EDC was added to the mixed solution. The reaction was continued under the same protective atmosphere and in an ice bath for a limited time. Then, the mixture was stirred at room temperature for 8 hours to ensure complete reaction. The reaction solution was washed with 150 mL of deionized water, repeated three times, to obtain the organic phase. The organic phase was dried over anhydrous Na₂SO₄ to remove water, filtered, and the organic solvent was removed by rotary evaporation. Further purification by column chromatography yielded the intermediate product Boc-Ala-F, with the following structural formula: ; Thirdly, under a protective atmosphere, 6.29 mmol of the intermediate product Boc-Ala-F was added to 50 mL of anhydrous dichloromethane. Under ice bath conditions, 0.19 mol of TFA was added dropwise for a limited time, followed by a limited time of stirring at room temperature. Then, 0.74 mmol of benzoic acid-terminated polyethylene glycol and 0.49 mmol of HOBT were added, and the mixture was stirred again. Finally, 0.88 mmol of EDC was added, and the reaction was carried out at room temperature for 12 hours to allow for complete reaction. The product was purified by column chromatography to obtain a white solid product labeled as PEG. n -Ala-F, (n=10~50), NMR spectrum as shown Figure 2 As shown, the structural formula is: , where X= (i.e., Ala), n=15.

[0032] X= This indicates that the carboxyl group of polyethylene glycol with benzoic acid as the terminal group and the hydroxyl group of perfluorooctyl ethanol are linked by a chiral group. In this embodiment, the chiral group is an alanine group. Therefore, the amphiphilic molecule prepared in this embodiment can also be called a chiral amphiphilic molecule.

[0033] By using polyethylene glycols with different degrees of polymerization benzoic acid as end groups, PEGs with different degrees of polymerization can be obtained. n -Ala-F, preferably n=10~50.

[0034] Furthermore, the timed ice bath stirring is stirring under ice bath conditions for 1-2 hours, the timed room temperature stirring is stirring under room temperature conditions for 4-8 hours, and the re-stirring time is 0.5-1 hour.

[0035] In this embodiment, the time for the ice bath is 1 hour, the time for stirring at room temperature is 8 hours, and the time for stirring again is 0.5 hours.

[0036] In this embodiment, nitrogen is used as the protective atmosphere.

[0037] It should be noted that in the amphiphilic molecules prepared in Examples 1 and 2, the hydrophilic portion is a linear PEG, the hydrophobic portion is a perfluorooctyl ethanol amphiphilic molecule, and the intermediate linking unit is a direct ester bond (e.g., PEG). n -F) or alanine linkage (e.g., PEG) n -Ala-F).

[0038] Example 3 below describes a method for synthesizing fluorinated liquid crystal block copolymers.

[0039] Example 3: This embodiment uses the synthesis of P2VP 40 -PFMA 15 Taking this as an example, the synthesis method of fluorinated liquid crystal block copolymers is introduced as follows: The method for synthesizing fluorinated liquid crystal block copolymers includes the following two steps: In the first step, under a protective atmosphere, 18.00 mmol of the hydrophilic monomer 2-VP, 0.20 mmol of the chain transfer reagent Furan-CTA, and 0.05 mmol of the initiator AIBN were dissolved in 2 mL of dioxane. The solution was first dehydrated and deoxygenated by three freeze-thaw cycles with liquid nitrogen, then placed in a constant-temperature environment for the first stirring, followed by rotary evaporation to remove the solvent, and finally a first precipitation purification to obtain the hydrophilic homopolymer P2VP. 40 The structural formula is: Where m=40; The second step involves adding 0.04 mmol of the macromolecular initiator P2VP. 40 0.005 mmol of initiator AIBN and 1.69 mmol of monomer FMA were dissolved in 2 mL of dioxane. The mixture was first frozen three times with liquid nitrogen to remove water and oxygen, then placed in a constant temperature environment for a second stirring. The solvent was then removed by rotary evaporation, and finally a second precipitation purification was performed to obtain a fluorinated liquid crystal block copolymer, labeled P2VP. 40 -PFMA 15 NMR spectrum as follows Figure 3 As shown, the structural formula is: , Where m=40 and n=15.

[0040] It should be noted that by adjusting the amount of hydrophilic monomer 2-VP and the corresponding parameters such as temperature and time in the preparation method, the degree of polymerization m of the hydrophilic homopolymer can be controlled, thereby further realizing the corresponding control of the m value of the fluorinated liquid crystal block copolymer.

[0041] It should be noted that the fluorinated liquid crystal block copolymer synthesized in this embodiment is a liquid crystal block copolymer composed of monomers linked at both ends. Specifically, 2-vinylpyridine is used as the first monomer, and a fluorinated liquid crystal chain homologous to amphiphilic molecules is used as the second monomer.

[0042] Furthermore, in the first and second steps, the constant temperature stirring is carried out using an oil bath method, with a constant temperature environment of 65~80℃. The first constant temperature stirring time is 6~8h, and the second constant temperature stirring time is 8~10h.

[0043] In this embodiment, the constant temperature environment temperature is 70°C, the first constant temperature stirring time is 7 hours, and the second constant temperature stirring time is 10 hours.

[0044] In this embodiment, the protective atmosphere is nitrogen.

[0045] In this embodiment, the first precipitation purification was performed using 35 mL of n-hexane, and a total of four precipitation purifications were performed.

[0046] In this embodiment, the second precipitation purification was performed using 40 mL of methanol, and a total of three precipitation purifications were performed.

[0047] The following describes a method for preparing nanofilm materials using amphiphilic molecules and fluorinated liquid crystal block copolymers as reactants.

[0048] Example 4: This embodiment describes the method of using the products of Example 2 and Example 3 to prepare nanofilm materials, as detailed below: The preparation method of nanofilm materials includes the following steps: PEG n -Ala-F and P2VP 40 -PFMA 15 Dissolved in the initial solvent at a 1:1 weight ratio to prepare P2VP 40 -PFMA 15 A mixture with a concentration of 0.5 mg / mL was prepared and allowed to stand until the sample was fully dissolved to obtain an initial solution. Then, the initial solution was placed at a preset temperature, and deionized water was added dropwise at a rate of 10 μL / min. Finally, gradient dialysis was performed, with a molecular weight cutoff of 3500 Da, to obtain an aqueous solution of microphase-separated nanofilm material, labeled P2VP. 40 -PFMA 15 @PEG n -Ala-F.

[0049] In this embodiment, THF is selected as the initial solvent.

[0050] In this embodiment, the preset temperature is 35°C.

[0051] In this embodiment, the volume of deionized water added is the same as the volume of the initial solvent.

[0052] In this embodiment, the sample was gently shaken during the addition of deionized water to ensure uniform mixing of the solution.

[0053] In this embodiment, gradient dialysis is performed in deionized water, which is replaced every 3 hours until the organic solvent is completely removed.

[0054] Example 5: This embodiment describes a method for preparing nanofilm materials using the products of Examples 2 and 3. The steps are basically the same as in Example 4, except that: P2VP 40 -PFMA 15 and PEG n The molar ratio of -Ala-F is changed from 1:1 to 1:3.

[0055] Example 6: This embodiment describes a method for preparing nanofilm materials using the products of Examples 2 and 3. The steps are basically the same as in Example 4, except that: P2VP 40 -PFMA 15 and PEG n The molar ratio of -Ala-F is changed from 1:1 to 1:5.

[0056] Examples 4 to 6 above describe methods for preparing nanofilm materials using amphiphilic molecules as reactants. Linear amphiphilic molecules can also be used as reactants and the same preparation method can be used to prepare nanofilms, only requiring appropriate adjustments to the dosage ratio.

[0057] The products of Examples 1 and 2 were tested by circular dichroism (CD) chromatography, as follows: Figure 4 As shown, where Figure 4 (A) shows the CD spectra of molecules from different parents. Figure 4 (B) shows the UV absorption spectra of different amphiphilic molecules, indicating that both amphiphilic molecules have obvious UV absorption and obvious CD signals.

[0058] The products of Examples 2 through 4 were tested by circular dichroism (CD) chromatography, such as... Figure 5 As shown, this indicates that the nanofilm material exhibits significant chiral characteristics.

[0059] The microstructure of the nanofilm materials prepared in Examples 3 to 6 was observed using TEM, and the interlayer distance of the microphase-separated fiber nanofilms was measured. Figure 6As shown in Table 1, the morphology and size of nanofilm materials can be controlled through process control.

[0060]

[0061] It can be seen that by assembling amphiphilic molecules and fluorinated liquid crystal block copolymers through a restricted gradient dialysis method, microphase-separated fibrous ribbon nanofilm materials can be constructed. By changing the doping ratio of amphiphilic molecules, the lateral alignment period and longitudinal length of the fibrous nanomaterials can be controlled. The interlayer distance of the microphase-separated assembly was successfully controlled to 7 nm. Furthermore, there is still room for further control if the doping ratio of amphiphilic molecules is increased. This is a new strategy for preparing special nanomaterials with adjustable size.

[0062] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended embodiments and their equivalents.

Claims

1. An amphiphilic molecule, characterized in that, The structural formula of the amphiphilic molecule is: ， Where X = or n = 10~50.

2. A fluorinated liquid crystal block copolymer, characterized in that, The structural formula of the fluorinated liquid crystal block copolymer is: ， Where m = 40 and n = 15.

3. The method for synthesizing the fluorinated liquid crystal block copolymer according to claim 2, characterized in that, It includes the following two steps: S21. Under a protective atmosphere, 2-VP, Furan-CTA and the initiator are dissolved in dioxane. After dehydration and deoxygenation, the mixture is placed in a constant temperature environment for the first constant temperature stirring. Then, the solvent is removed by rotary evaporation. Finally, the first precipitation purification is performed to obtain the macromolecular initiator. S22. The macromolecular initiator, initiator and ethyl perfluorooctyl acrylate are dissolved in dioxane, and after dehydration and deoxygenation treatment, they are placed in a constant temperature environment for a second constant temperature stirring. Then, the solvent is removed by rotary evaporation, and finally a second precipitation purification is performed to obtain the fluorinated liquid crystal block copolymer.

4. A method for preparing a microphase-separated nanofilm material, characterized in that, The reactants include the amphiphilic molecule of claim 1 and the fluorinated liquid crystal block copolymer of claim 2, and the preparation method of the microphase-separated nanofilm material includes the following three steps: S31. Dissolve the amphiphilic molecule and the fluorinated liquid crystal block copolymer in an initial solvent, and let stand until fully dissolved to obtain an initial solution; S32. Place the initial solution at a preset temperature and add deionized water dropwise to obtain a diluted solution; S33. The diluted solution is subjected to gradient dialysis to retain a molecular weight cutoff of 3500 Da, thereby obtaining an aqueous solution of microphase-separated nanofilm material.

5. The method for preparing microphase-separated nanofilm materials according to claim 4, characterized in that, The molar ratio of the amphiphilic molecule to the fluorinated liquid crystal block copolymer is 1 to 5:1, and the initial solvent is THF, which is used to prepare a mixture with a concentration of 0.5 mg / mL of the fluorinated liquid crystal block copolymer.

6. The method for preparing microphase-separated nanofilm materials according to claim 4, characterized in that, The preset temperature is 35℃.

7. The method for preparing microphase-separated nanofilm materials according to claim 4, characterized in that, The volume of the deionized water is the same as the volume of the initial solvent.

8. A method for preparing a microphase-separated chiral nanofilm material, characterized in that, The reactants comprise the amphiphilic molecule of claim 1 and the fluorinated liquid crystal block copolymer of claim 2, wherein X = The preparation method of the microphase-separated chiral nanofilm material includes the following three steps: S31. Dissolve the amphiphilic molecule and the fluorinated liquid crystal block copolymer in an initial solvent, and let stand until fully dissolved to obtain an initial solution; S32. Place the initial solution at a preset temperature and add deionized water dropwise to obtain a diluted solution; S33. The diluted solution is subjected to gradient dialysis to retain a molecular weight cutoff of 3500 Da, thereby obtaining an aqueous solution of microphase-separated nanofilm material.

Images