Fluorene-like derivatives and applications and methods of making the compounds
By using sodium benzenesulfinate as a free radical carrier in a carbon dioxide atmosphere via visible light catalysis, the environmentally unfriendly problem of preparing fluorene derivatives in existing technologies has been solved. This method achieves a simple and efficient synthesis of fluorene derivatives with a wide range of applicable substrates and high product yield.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- MINDU INNOVATION LAB
- Filing Date
- 2022-06-01
- Publication Date
- 2026-07-14
AI Technical Summary
Existing methods require large amounts of oxidants or metal reagents to prepare fluorene derivatives, and the reaction conditions are harsh and environmentally unfriendly, making it impossible to prepare fluorene derivatives with simple structures.
A visible-light photocatalyst-based radical pathway was employed, using sodium benzenesulfinate as a radical transfer agent to cyclize 1,6-enyne compounds in a carbon dioxide atmosphere. Fluorene derivatives were prepared in a one-step reaction at room temperature using photocatalysts such as Ru(bpy)3Cl2, [Ir(ppy)2(dtbbpy)](PF6), and 4-CzIPN.
A simple, efficient, and green synthesis of fluorene derivatives was achieved. Two new rings and two carbon-carbon bonds were constructed at room temperature via visible light catalysis. The reaction was mild, environmentally friendly, economical, applicable to a wide range of substrates, and yielded good product yields.
Smart Images
Figure CN117186005B_ABST