Method, device, equipment and storage medium for determining microbial safety of sterilization machine

Abstract

The embodiment of the application provides a method, device and equipment for determining the microbial safety of a sterilization machine, and a storage medium, wherein the method for determining the microbial safety of the sterilization machine comprises: calculating the actual sterilization intensity of the sterilization machine on a target liquid according to parameter information of at least one sterilization section of the sterilization machine; comparing the actual sterilization intensity with a reference sterilization intensity; and determining that the microbial safety of the sterilization machine meets a predetermined safety requirement in the case that the actual sterilization intensity is higher than the reference sterilization intensity. The technical solution of the embodiment of the application can calculate the actual sterilization intensity of the sterilization machine on the target liquid, thereby realizing quantitative evaluation of the sterilization efficiency of the sterilization machine, determining the microbial safety of the sterilization machine, and reducing the labor of the staff, improving the calculation efficiency and accuracy.

Description

Technical Field

[0001] This application relates to the field of computer technology, and in particular to a method for determining the microbial safety of a sterilizer, a device for determining the microbial safety of a sterilizer, an electronic device, and a computer-readable storage medium. Background Technology

[0002] In related technologies, the calculation of heat treatment processes depends on the inactivation of microorganisms within a specific time and temperature range. The time required to reduce the microbial population by a factor of 10 at a constant temperature is called the D-value of the process, which provides a quantitative indicator of the heat resistance of microbial cells or spores. The process of quantifying the sterilization intensity provided to food raw materials based on a multiple of the D-value at a reference temperature (i.e., a 6D process or a 12D process, etc.) is also called the F-value under reference conditions. The F-value usually requires manual calculation, which is labor-intensive, inefficient, and makes it difficult to quantitatively assess the sterilization efficiency of ultra-high temperature sterilizers. Summary of the Invention

[0003] This application provides a method, apparatus, device, and storage medium for determining the microbial safety of a sterilizer, in order to solve or alleviate one or more technical problems in the prior art.

[0004] As a first aspect of this application, this application provides a method for determining the microbial safety of a sterilizer, including:

[0005] Calculate the actual sterilization intensity of the sterilizer on the target liquid based on the parameter information of at least one sterilization section of the sterilizer;

[0006] Compare the actual sterilization intensity with the reference sterilization intensity;

[0007] When the actual sterilization intensity is higher than the reference sterilization intensity, it is determined that the microbial safety of the sterilizer meets the predetermined safety requirements.

[0008] In one embodiment, calculating the actual sterilization intensity of the sterilizer on the target liquid based on parameter information of at least one sterilization section of the sterilizer includes:

[0009] Read the parameter information of each sterilization stage;

[0010] Determine the heat exchange mode between the target liquid and the corresponding heat exchange liquid in each sterilization section;

[0011] Based on the parameter information and heat exchange method, calculate the sterilization time and sterilization temperature of the target liquid in each sterilization zone;

[0012] Based on the sterilization time and temperature of the target liquid in each sterilization zone, calculate the sterilization intensity of each sterilization zone on the target liquid;

[0013] The actual sterilization intensity of the sterilizer on the target liquid is calculated based on the sterilization intensity of each sterilization stage.

[0014] In one embodiment, the sterilization intensity of each sterilization stage on the target liquid is calculated based on the sterilization time and temperature of the target liquid in each sterilization stage, including:

[0015] When the sterilization section is a constant temperature section

[0016] When the sterilization section is not a constant temperature section

[0017] Where F0 is the sterilization intensity of the target liquid in the sterilization zone, t is the sterilization time of the target liquid in the sterilization zone, T is the sterilization temperature of the target liquid in the sterilization zone, and Z is a constant.

[0018] In one implementation, the sterilization time and temperature of the target liquid in each sterilization zone are calculated based on parameter information and heat exchange method, including:

[0019] Based on the parameter information and heat exchange method, the sterilization time of the target liquid in each sterilization zone is calculated. This is especially important when the heat exchange method involves the same liquid. When the heat exchange method involves heat exchange with different types of liquids

[0020] The sterilization temperature of the target liquid is calculated based on the sterilization time of the target liquid in each sterilization zone, where T=T1+k×t;

[0021] Where t is the sterilization time of the target liquid in each sterilization section, D is the inner diameter of the sterilization section, d is the inner diameter of each sterilization tube in the sterilization section, n is the number of sterilization tubes in the sterilization section, L is the length of the sterilization tubes in the sterilization section, Q is the flow rate of the sterilizer, T is the sterilization temperature of the target liquid, T1 is the inlet temperature of each sterilization section, and k is a constant.

[0022] In one embodiment, the method for determining the microbial safety of the sterilizer further includes:

[0023] Based on the sterilization time and temperature of the target liquid in each sterilization stage, a temperature change curve of the target liquid during the sterilization process is established.

[0024] As a second aspect of this application, this application provides a device for determining the microbial safety of a sterilizer, comprising:

[0025] The calculation module is used to calculate the actual sterilization intensity of the sterilizer on the target liquid based on the parameter information of at least one sterilization section of the sterilizer.

[0026] The comparison module is used to compare the actual sterilization intensity with the reference sterilization intensity;

[0027] The determination module is used to determine whether the microbial safety of the sterilizer meets the predetermined safety requirements when the actual sterilization intensity is higher than the reference sterilization intensity.

[0028] In one implementation, the computing module includes:

[0029] The reading submodule is used to read parameter information for each sterilization stage;

[0030] The judgment submodule is used to determine the heat exchange mode between the target liquid and the corresponding heat exchange liquid in each sterilization section;

[0031] The first calculation submodule is used to calculate the sterilization time and sterilization temperature of the target liquid in each sterilization section based on parameter information and heat exchange method;

[0032] The second calculation submodule is used to calculate the sterilization intensity of the target liquid in each sterilization stage based on the sterilization time and sterilization temperature of the target liquid in each sterilization stage.

[0033] The third calculation submodule is used to calculate the actual sterilization intensity of the sterilizer on the target liquid based on the sterilization intensity of each sterilization stage on the target liquid.

[0034] In one embodiment, the device for determining the microbial safety of the sterilizer further includes:

[0035] The curve generation module is used to generate a temperature change curve of the target liquid during the sterilization process based on the sterilization time and temperature of the target liquid in each sterilization stage.

[0036] As a third aspect of the embodiments of this application, the embodiments of this application provide an electronic device, including:

[0037] At least one processor; and

[0038] A memory that is communicatively connected to at least one processor; wherein,

[0039] The memory stores instructions that can be executed by at least one processor, such that the at least one processor is able to perform the method of any of the above-described embodiments.

[0040] As a fourth aspect of the present application, the present application provides a computer-readable storage medium storing computer instructions, which, when executed by a processor, implement the methods of any of the above-described aspects.

[0041] The embodiments of this application employ the above-described technical solution to automatically calculate the actual sterilization intensity of the sterilizer on the target liquid, thereby achieving a quantitative assessment of the sterilization efficiency of the sterilizer, determining the microbial safety of the sterilizer, and reducing the workload of staff while improving calculation efficiency and accuracy.

[0042] The above overview is for illustrative purposes only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments, and features described above, further aspects, embodiments, and features of this application will become readily apparent from the accompanying drawings and the following detailed description. Attached Figure Description

[0043] In the accompanying drawings, unless otherwise specified, the same reference numerals throughout the various drawings denote the same or similar parts or elements. These drawings are not necessarily drawn to scale. It should be understood that these drawings depict only some embodiments disclosed in this application and should not be construed as limiting the scope of this application.

[0044] Figure 1 A flowchart illustrating a method for determining the microbial safety of a sterilizer according to an embodiment of this application is shown.

[0045] Figure 2 A flowchart illustrating the calculation of the actual sterilization intensity of the sterilizer on the target liquid is shown.

[0046] Figure 3 A cross-sectional schematic diagram of the sterilization section of a sterilizer according to an embodiment of this application is shown;

[0047] Figure 4 A schematic diagram showing the sterilization temperature and sterilization intensity of the target liquid in the non-constant temperature range;

[0048] Figure 5 The temperature change curves of the target liquid under different sterilization flow rates are shown.

[0049] Figure 6 A structural block diagram of a device for determining the microbial safety of a sterilizer according to an embodiment of this application is shown.

[0050] Figure 7 A block diagram of an electronic device used to implement the method for determining the microbial safety of a sterilizer according to embodiments of this application is shown. Detailed Implementation

[0051] In the following description, only certain exemplary embodiments are briefly described. As those skilled in the art will recognize, the described embodiments can be modified in various ways without departing from the spirit or scope of this application. Therefore, the drawings and description are considered to be exemplary in nature and not restrictive.

[0052] like Figure 1 As shown, the method for determining the microbial safety of a sterilizer according to an embodiment of the first aspect of this application includes:

[0053] Step S101: Calculate the actual sterilization intensity of the sterilizer on the target liquid based on the parameter information of at least one sterilization section of the sterilizer;

[0054] Step S102: Compare the actual sterilization intensity with the reference sterilization intensity;

[0055] Step S103: When the actual sterilization intensity is higher than the reference sterilization intensity, determine that the microbial safety of the sterilizer meets the predetermined safety requirements.

[0056] For example, the sterilizer can be an ultra-high temperature sterilizer. The sterilizer may include multiple sterilization sections, through which the target liquid flows sequentially during sterilization. Each sterilization section can be a tubular sterilization section or a sheathed sterilization section. In the case of a tubular sterilization section, multiple sterilization tubes are provided within the sterilization section; in the case of a sheathed sterilization section, only one sterilization tube is provided within the sterilization section. The actual sterilization intensity of the sterilizer on the target liquid is the sum of the sterilization intensities of the multiple sterilization sections on the target liquid.

[0057] The reference sterilization intensity can be the sterilization intensity of sterilization machines already in operation, provided that the microbiological safety of these machines meets the predetermined safety requirements. If the actual sterilization intensity of a sterilization machine not yet in operation is higher than or equal to the reference sterilization intensity, then the microbiological safety of that machine is determined to meet the predetermined safety requirements, and it can be put into operation. If the actual sterilization intensity of a sterilization machine not yet in operation is lower than the reference sterilization intensity, then the microbiological safety of that machine is determined to not meet the predetermined safety requirements.

[0058] The method for determining the microbial safety of a sterilizer according to the embodiments of this application can automatically calculate the actual sterilization intensity of the sterilizer on the target liquid, thereby realizing a quantitative assessment of the sterilization efficiency of the sterilizer, determining the microbial safety of the sterilizer, and reducing the workload of staff while improving calculation efficiency and accuracy.

[0059] In one implementation, such as Figure 2 As shown, in step S101, calculating the actual sterilization intensity of the sterilizer on the target liquid based on parameter information of at least one sterilization section of the sterilizer may include:

[0060] Step S201: Read the parameter information of each sterilization segment.

[0061] The parameters of the sterilization section may include the inner diameter of the sterilization section, the inner diameter of each sterilization tube in the sterilization section, the number of sterilization tubes in the sterilization section, the length of each sterilization tube in the sterilization section, the flow rate of the sterilizer, the inlet temperature of each sterilization section, and the outlet temperature of each sterilization section.

[0062] Step S202: Determine the heat exchange method between the target liquid and the corresponding heat exchange liquid in each sterilization section.

[0063] For example, refer to Figure 3 During the sterilization process of the target liquid, the target liquid can be located inside the sterilization tube 2, and the heat exchange liquid can be located between the outer wall of the sterilization tube 2 and the inner wall of the sterilization section 1. The heat exchange method between the target liquid and the heat exchange liquid can include heat exchange with the same type of liquid and heat exchange with different types of liquids. For example, when the target liquid is milk, the heat exchange method between the target liquid and the heat exchange liquid is heat exchange with the same type of liquid; when the heat exchange liquid is another liquid such as water, the heat exchange method between the target liquid and the heat exchange liquid is heat exchange with different types of liquids.

[0064] Step S203: Calculate the sterilization time and sterilization temperature of the target liquid in each sterilization zone based on the parameter information and heat exchange method.

[0065] Step S204: Calculate the sterilization intensity of each sterilization stage on the target liquid based on the sterilization time and temperature of the target liquid in each sterilization stage.

[0066] Step S205: Calculate the actual sterilization intensity of the sterilizer on the target liquid based on the sterilization intensity of each sterilization stage.

[0067] In step S205, the sterilization intensity of the target liquid by the multiple sterilization stages is summed to obtain the actual sterilization intensity of the sterilizer on the target liquid.

[0068] Therefore, by following the steps above, the actual sterilization intensity of the sterilizer on the target liquid can be accurately calculated, thus achieving a quantitative assessment of the sterilization efficiency of the sterilizer without the need for manual calculation.

[0069] In one implementation, combined with Figure 4 In step S204, the sterilization intensity of each sterilization zone on the target liquid is calculated based on the sterilization time and temperature of the target liquid in each sterilization zone. This may include: when the sterilization zone is a constant temperature zone, When the sterilization section is not a constant temperature section Where F0 is the sterilization intensity of the target liquid in the sterilization zone, t is the sterilization time of the target liquid in the sterilization zone, T is the sterilization temperature of the target liquid in the sterilization zone, and Z is a constant.

[0070] For example, during the ultra-high temperature sterilization process of the sterilizer, the target liquid flows through multiple sterilization sections and is continuously processed. These sterilization sections may include isothermal and non-isothermal sections; the non-isothermal section may include a heating section and a cooling section. Correspondingly, the continuous processing may include a heating process, an isothermal process, and a cooling process. When the heat exchange method is the same liquid heat exchange, the target liquid inside the sterilization tube can be milk that is about to be heated, and the heat exchange liquid outside the sterilization tube can be milk that needs to be cooled after sterilization. This allows for heat recovery, thereby reducing energy consumption.

[0071] In the above formula, the constant Z value can be assumed to be 10. For specific Bacillus species, it can be replaced accordingly based on the measured Z value. When the sterilization stage is a constant temperature stage, the time the target liquid, such as milk, is maintained at a constant temperature T is t. When the sterilization stage is a non-constant temperature stage, the temperature T of the target liquid gradually increases or decreases, and t is the time required for heating or cooling. Here, T is in degrees Celsius (°C), and t can be in seconds (s).

[0072] Therefore, the sterilization intensity of the constant temperature section and the non-constant temperature section on the target liquid can be calculated according to the above formula, thus accurately calculating the sterilization intensity of the sterilizer on the target liquid.

[0073] In one embodiment, step S203, calculating the sterilization time and temperature of the target liquid in each sterilization zone based on parameter information and heat exchange method, may include:

[0074] Based on the parameter information and heat exchange method, the sterilization time of the target liquid in each sterilization zone is calculated. Specifically, when the heat exchange method is the same liquid heat exchange, When the heat exchange method involves heat exchange with different types of liquids

[0075] For example, when the heat exchange method is the same liquid heat exchange, the flow rate of the target liquid Where Q is the flow rate of the sterilizer, measured in tons per hour (t / h); S is the cross-sectional area of ​​the sterilization tube; D is the inner diameter of the sterilization section, measured in millimeters (mm); d is the inner diameter of each sterilization tube within the sterilization section, measured in mm; and n is the number of sterilization tubes within the sterilization section. The sterilization time of the target liquid within each sterilization section is then determined. Where L is the length of the sterilization tube within the sterilization section, and the unit of L is meters (m).

[0076] When the heat exchange method is non-homogeneous liquid heat exchange, the flow rate of the target liquid Sterilization time of the target liquid in each sterilization stage

[0077] The sterilization temperature of the target liquid is calculated based on the sterilization time of the target liquid in each sterilization zone. Where T = T1 + k × t, T is the sterilization temperature of the target liquid, and k is a constant.

[0078] For example, when the sterilization section is a constant-temperature section, k can be 0. When the sterilization section is a non-constant-temperature section, such as a heating section, combined with... Figure 4 In the left figure, the sterilization temperature of the target liquid is a linear function of the sterilization time. Point A is the inlet of the sterilization section, point B is the outlet of the sterilization section, and the line connecting points A and B represents the slope of the linear function graph. T1 is the inlet temperature of the sterilization section, which is the sterilization temperature corresponding to point A; T2 is the outlet temperature of the sterilization section, which is the sterilization temperature corresponding to point B; t1 is the inlet time of the sterilization section, which is the time corresponding to point A; and t2 is the outlet time of the sterilization section, which is the time corresponding to point B. Figure 4 The shaded area in the right figure represents the cumulative sterilization intensity during the entire heating process from point A to point B.

[0079] Therefore, the sterilization time and temperature of the target liquid in the corresponding sterilization zone can be effectively calculated, and the sterilization intensity of each sterilization zone can be accurately calculated based on the sterilization time and temperature.

[0080] In one implementation, such as Figure 5 As shown, the method for determining the microbial safety of the sterilizer also includes: establishing a temperature change curve of the target liquid during the sterilization process based on the sterilization time and temperature of the target liquid in each sterilization section.

[0081] For example, Figure 5 The left figure shows the temperature change curve of the target liquid during the sterilization process at a sterilization flow rate of 11 tons / hour. Figure 5 The right figure shows the temperature change curve of the target liquid during the sterilization process at a sterilization flow rate of 12 tons / hour. Figure 5 It can be clearly seen that the target liquid underwent a heating process, a isothermal process, and a cooling process during continuous processing.

[0082] Therefore, the temperature change curve can be automatically output, allowing users to more intuitively observe the temperature changes of the target liquid during continuous processing.

[0083] In some embodiments, the method for determining the microbial safety of the sterilizer can be implemented as a computer software program. Combining all the above formulas can constitute a calculation program for calculating the actual sterilization intensity. The operation of the calculation program mainly involves five steps: a) measuring the parameter information of each sterilization stage of the sterilizer; b) converting the program input data format; c) executing the program code; d) program execution; and e) outputting the results.

[0084] Referring to Table 1, all content except the first row in Table 1 consists of program input. The first parameter of sterilization temperature T (i.e., 5℃) is the inlet temperature of the ultra-high temperature sterilizer, and the remaining parameters are the outlet temperatures of each sterilization section. For example, if the sterilizer includes 10 sterilization sections, then T requires a total of 11 parameters. The first parameter of sterilization tube inner diameter d defaults to 0 and does not need to be modified. The first parameter of sterilization tube length L defaults to 0 and does not need to be modified. The first parameter of the number of sterilization tubes n in each sterilization section defaults to 0 and does not need to be modified. The inner diameter D of the sterilization section defaults to 0. If there is heat exchange with the same liquid in the cooling section (e.g., milk-to-milk heat exchange), then D is the inner diameter of the sterilization section.

[0085] Table 1

[0086]

[0087] During the calculation program's execution, the R language must first be installed. R is a programming language and software environment used for statistical analysis, graphical representation, and reporting. Then, configure R as an environment variable in the system's advanced settings, adding the directory containing the R.exe file to the PATH. Afterward, the script is invoked via cmd. For example, on Linux systems, the format is `R CMDBATCH [options]my.R [outfile]`; on Windows systems, the format is `R CMD BATCH [my.R]`. The code execution logic is as follows: data reading → heat exchange method determination → sterilization time calculation → formatting and data merging → temperature rise curve function expression → sterilization intensity calculation → plotting → outputting images and statistical data.

[0088] The program outputs three files: "Flow_11t_result.csv", "Flow_12t_result.csv", "Flow_11t_UHT.png", and "Flow_12t_UHT.png". The CSV file records the time, temperature, and sterilization intensity of the target liquid as it passes through each sterilization stage of the sterilizer (as shown in Tables 2 and 3); the PNG file is a schematic diagram of the sterilization process of the target liquid (e.g., ...). Figure 5 As shown in the image, the Rout file records the program's execution process.

[0089] Table 2

[0090] F0 temperature time 1 1.92E-06 7 31.67 2 1.39E-05 78.9 13.03 3 0.00030168 79.4 21.71 4 0.07651729 96.3 8.69 5 4.6931015 126.8 17.37 6 1.55632783 137.5 2.32 7 1.7605135 136.8 26.06 8 0.00016763 97 43.4 9 0 24.1 18.87 10 8.087 24.1 183.11

[0091] Table 3

[0092] F0 temperature time 1 1.92E-06 7 31.67 2 1.39E-05 78.9 13.03 3 0.000030168 79.4 21.71 4 0.07651729 96.3 8.69 5 4.6931015 126.8 17.37 6 1.55632783 137.5 2.32 7 1.7605135 136.8 26.06 8 0.00016763 97 43.4 9 0 24.1 18.87 10 8.087 24.1 183.11

[0093] Table 2 shows the sterilization intensity, sterilization temperature, and sterilization time of the target liquid in each sterilization stage of the sterilizer when the sterilization flow rate is 11 t / h. Table 2 also shows the sterilization intensity, sterilization temperature, and sterilization time of the target liquid in each sterilization stage of the sterilizer when the sterilization flow rate is 12 t / h. The sterilizer in Tables 2 and 3 has a total of nine sterilization stages. The second column represents the sterilization intensity; rows 2-10 of the second column show the sterilization intensity of each sterilization stage, and row 11 of the second column shows the total sterilization intensity of the sterilizer. The third column represents the sterilization temperature; row 2 of the third column shows the inlet temperature of the sterilizer, and rows 3-10 of the third column show the outlet temperature of each sterilization stage. The fourth column represents the sterilization time; rows 2-10 of the fourth column show the time the target liquid spent in each sterilization stage, and row 11 shows the total time.

[0094] The calculation program described in this application greatly simplifies the calculation process for the sterilization intensity of ultra-high temperature sterilizers, improving work and research efficiency. Furthermore, the program is fast and accurate. In addition, the program outputs diverse results, making it convenient for operators to use and share.

[0095] Figure 6 A structural block diagram of a device for determining the microbial safety of a sterilizer according to an embodiment of the second aspect of this application is shown. Figure 7 As shown, the device may include:

[0096] The calculation module 601 is used to calculate the actual sterilization intensity of the sterilizer on the target liquid based on the parameter information of at least one sterilization section of the sterilizer.

[0097] Comparison module 602 is used to compare the actual sterilization intensity with the reference sterilization intensity;

[0098] The determination module 603 is used to determine whether the microbial safety of the sterilizer meets the predetermined safety requirements when the actual sterilization intensity is higher than the reference sterilization intensity.

[0099] In one embodiment, the computing module 601 includes:

[0100] The reading submodule is used to read parameter information for each sterilization stage;

[0101] The judgment submodule is used to determine the heat exchange mode between the target liquid and the corresponding heat exchange liquid in each sterilization section;

[0102] The first calculation submodule is used to calculate the sterilization time and sterilization temperature of the target liquid in each sterilization section based on parameter information and heat exchange method;

[0103] The second calculation submodule is used to calculate the sterilization intensity of the target liquid in each sterilization stage based on the sterilization time and sterilization temperature of the target liquid in each sterilization stage.

[0104] The third calculation submodule is used to calculate the actual sterilization intensity of the sterilizer on the target liquid based on the sterilization intensity of each sterilization stage on the target liquid.

[0105] In one implementation, the second calculation submodule is further configured to:

[0106] When the sterilization section is a constant temperature section

[0107] When the sterilization section is not a constant temperature section

[0108] Where F0 is the sterilization intensity of the target liquid in the sterilization zone, t is the sterilization time of the target liquid in the sterilization zone, T is the sterilization temperature of the target liquid in the sterilization zone, and Z is a constant.

[0109] In one implementation, the first computing submodule is further configured to:

[0110] Based on the parameter information and heat exchange method, the sterilization time of the target liquid in each sterilization zone is calculated. This is especially important when the heat exchange method involves the same liquid. When the heat exchange method involves heat exchange with different types of liquids

[0111] The sterilization temperature of the target liquid is calculated based on the sterilization time of the target liquid in each sterilization zone, where T=T1+k×t;

[0112] Where t is the sterilization time of the target liquid in each sterilization section, D is the inner diameter of the sterilization section, d is the inner diameter of each sterilization tube in the sterilization section, n is the number of sterilization tubes in the sterilization section, L is the length of the sterilization tubes in the sterilization section, Q is the flow rate of the sterilizer, T is the sterilization temperature of the target liquid, T1 is the inlet temperature of each sterilization section, and k is a constant.

[0113] In one embodiment, the device for determining the microbial safety of the sterilizer further includes:

[0114] The curve generation module is used to generate a temperature change curve of the target liquid during the sterilization process based on the sterilization time and temperature of the target liquid in each sterilization stage.

[0115] The functions of each module in each device of the embodiments of this application can be found in the corresponding descriptions in the above methods, and will not be repeated here.

[0116] Figure 7 A structural block diagram of an electronic device according to an embodiment of this application is shown. Figure 7 As shown, the electronic device includes a memory 710 and a processor 720. The memory 710 stores instructions that can be executed on the processor 720. When the processor 720 executes the instructions, it implements the method for determining the microbial safety of the sterilizer in the above embodiments. The number of memories 710 and processors 720 can be one or more. This electronic device is intended to represent various forms of digital computers, such as laptop computers, desktop computers, workbenches, personal digital assistants, servers, blade servers, mainframe computers, and other suitable computers. The electronic device can also represent various forms of mobile devices, such as personal digital processors, cellular phones, smartphones, wearable devices, and other similar computing devices. The components shown herein, their connections and relationships, and their functions are merely examples and are not intended to limit the implementation of the present application described and / or claimed herein.

[0117] The electronic device may also include a communication interface 730 for communicating with external devices and exchanging data. The devices are interconnected using different buses and can be mounted on a common motherboard or otherwise as needed. The processor 720 can process instructions executed within the electronic device, including instructions stored in or on memory to display graphical information of a GUI on an external input / output device (such as a display device coupled to the interface). In other embodiments, multiple processors and / or multiple buses can be used with multiple memories and multiple memory modules, if desired. Similarly, multiple electronic devices can be connected, each providing some of the necessary operations (e.g., as a server array, a group of blade servers, or a multiprocessor system). The bus can be divided into address buses, data buses, control buses, etc. For ease of illustration, Figure 7 The bus is represented by a single thick line, but this does not mean that there is only one bus or one type of bus.

[0118] Optionally, in a specific implementation, if the memory 710, processor 720 and communication interface 730 are integrated on a single chip, the memory 710, processor 720 and communication interface 730 can communicate with each other through an internal interface.

[0119] It should be understood that the aforementioned processor can be a Central Processing Unit (CPU), or other general-purpose processors, Digital Signal Processors (DSPs), Application Specific Integrated Circuits (ASICs), Field-Programmable Gate Arrays (FPGAs), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. General-purpose processors can be microprocessors or any conventional processor. It is worth noting that the processor can be a processor supporting Advanced Reduced Instruction Set Machines (ARM) architecture.

[0120] This application provides a computer-readable storage medium (such as the memory 710 described above) that stores computer instructions, which, when executed by a processor, implement the method provided in this application.

[0121] Optionally, the memory 710 may include a program storage area and a data storage area, wherein the program storage area may store the operating system and applications required for at least one function; the data storage area may store data created based on the use of the electronic device, etc. Furthermore, the memory 710 may include high-speed random access memory, and may also include non-transitory memory, such as at least one disk storage device, flash memory device, or other non-transitory solid-state storage device. In some embodiments, the memory 710 may optionally include memory remotely located relative to the processor 720, and these remote memories can be connected to the electronic device via a network. Examples of such networks include, but are not limited to, the Internet, corporate intranets, local area networks, mobile communication networks, and combinations thereof.

[0122] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of this application. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of those different embodiments or examples.

[0123] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, "a plurality of" means two or more, unless otherwise explicitly specified.

[0124] Any process or method description in the flowchart or otherwise herein can be understood as representing a module, segment, or portion of code comprising one or more (two or more) executable instructions for implementing a particular logical function or process. Furthermore, the scope of the preferred embodiments of this application includes additional implementations in which functions may be performed not in the order shown or discussed, including substantially simultaneously or in reverse order depending on the functionality involved.

[0125] The logic and / or steps represented in the flowchart or otherwise described herein, for example, can be considered as a sequenced list of executable instructions for implementing logical functions, and can be embodied in any computer-readable medium for use by, or in conjunction with, an instruction execution system, apparatus, or device (such as a computer-based system, a processor-included system, or other system that can fetch and execute instructions from and from an instruction execution system, apparatus, or device).

[0126] It should be understood that various parts of this application can be implemented using hardware, software, firmware, or a combination thereof. In the above embodiments, multiple steps or methods can be implemented using software or firmware stored in memory and executed by a suitable instruction execution system. All or part of the steps of the methods in the above embodiments can be implemented by a program instructing related hardware, the program being stored in a computer-readable storage medium, which, when executed, includes one or a combination of the steps of the method embodiments.

[0127] Furthermore, the functional units in the various embodiments of this application can be integrated into a processing module, or each unit can exist physically separately, or two or more units can be integrated into a module. The integrated module can be implemented in hardware or as a software functional module. If the integrated module is implemented as a software functional module and sold or used as an independent product, it can also be stored in a computer-readable storage medium. This storage medium can be a read-only memory, a disk, or an optical disk, etc.

[0128] The above are merely specific embodiments of this application, but the scope of protection of this application is not limited thereto. Any person skilled in the art can easily conceive of various variations or substitutions within the technical scope disclosed in this application, and these should all be included within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.

Claims

1. A method for determining the microbial safety of a sterilizer, characterized in that, include: Based on the parameter information of at least one sterilization section of the sterilizer, calculate the actual sterilization intensity of the sterilizer on the target liquid; Compare the actual sterilization intensity with the reference sterilization intensity; If the actual sterilization intensity is higher than the reference sterilization intensity, it is determined that the microbial safety of the sterilization machine meets the predetermined safety requirements. The calculation of the actual sterilization intensity of the sterilizer on the target liquid, based on parameter information of at least one sterilization section of the sterilizer, includes: Read the parameter information of each of the sterilization segments; Determine the heat exchange mode between the target liquid and the corresponding heat exchange liquid in each of the sterilization sections; Based on the parameter information and the heat exchange method, the sterilization time and sterilization temperature of the target liquid in each sterilization section are calculated; The sterilization intensity of each sterilization stage on the target liquid is calculated based on the sterilization time and sterilization temperature of the target liquid in each sterilization stage. The actual sterilization intensity of the sterilizer on the target liquid is calculated based on the sterilization intensity of each sterilization stage on the target liquid.

2. The method according to claim 1, characterized in that, Based on the sterilization time and temperature of the target liquid in each sterilization zone, the sterilization intensity of each sterilization zone on the target liquid is calculated, including: When the sterilization section is a constant temperature section ; When the sterilization section is not a constant temperature section ; Wherein, F0 is the sterilization intensity of the target liquid in the sterilization zone, t is the sterilization time of the target liquid in the sterilization zone, T is the sterilization temperature of the target liquid in the sterilization zone, and Z is a constant.

3. The method according to claim 1, characterized in that, Based on the parameter information and the heat exchange method, the sterilization time and sterilization temperature of the target liquid in each sterilization zone are calculated, including: Based on the parameter information and the heat exchange method, the sterilization time of the target liquid in each sterilization zone is calculated, wherein the heat exchange method is the same type of liquid heat exchange. When the heat exchange method involves heat exchange with different types of liquids, ; The sterilization temperature of the target liquid is calculated based on the sterilization time of the target liquid in each sterilization zone, wherein... ; Wherein, t is the sterilization time of the target liquid in each sterilization section, D is the inner diameter of the sterilization section, d is the inner diameter of each sterilization tube in the sterilization section, n is the number of sterilization tubes in the sterilization section, L is the length of the sterilization tubes in the sterilization section, Q is the flow rate of the sterilizer, T is the sterilization temperature of the target liquid, T1 is the inlet temperature of each sterilization section, and k is a constant.

4. The method according to claim 1, characterized in that, Also includes: Based on the sterilization time and temperature of the target liquid in each sterilization section, a temperature change curve of the target liquid during the sterilization process is established.

5. A device for determining the microbial safety of a sterilizer, characterized in that, include: The calculation module is used to calculate the actual sterilization intensity of the sterilizer on the target liquid based on the parameter information of at least one sterilization section of the sterilizer. The comparison module is used to compare the actual sterilization intensity with the reference sterilization intensity; The determination module is used to determine whether the microbial safety of the sterilization machine meets predetermined safety requirements when the actual sterilization intensity is higher than the reference sterilization intensity. The calculation module includes: The reading submodule is used to read the parameter information of each of the sterilization segments; The judgment submodule is used to determine the heat exchange mode between the target liquid and the corresponding heat exchange liquid in each of the sterilization sections; The first calculation submodule is used to calculate the sterilization time and sterilization temperature of the target liquid in each sterilization section based on the parameter information and the heat exchange method. The second calculation submodule is used to calculate the sterilization intensity of each sterilization segment on the target liquid based on the sterilization time and sterilization temperature of the target liquid in each sterilization segment. The third calculation submodule is used to calculate the actual sterilization intensity of the sterilizer on the target liquid based on the sterilization intensity of each sterilization segment on the target liquid.

6. The apparatus according to claim 5, characterized in that, Also includes: The curve establishment module is used to establish a temperature change curve of the target liquid during the sterilization process based on the sterilization time and sterilization temperature of the target liquid in each sterilization section.

7. An electronic device, characterized in that, include: At least one processor; as well as A memory communicatively connected to the at least one processor; wherein, The memory stores instructions that can be executed by the at least one processor to enable the at least one processor to perform the method of any one of claims 1-4.

8. A computer-readable storage medium storing computer instructions that, when executed by a processor, implement the method as described in any one of claims 1-4.

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