Methods, apparatus, electronic devices and storage media for determining the similarity of radiotherapy plans

Abstract

This application discloses a method, apparatus, electronic device, and storage medium for determining the similarity of radiotherapy plans. The method includes: acquiring a first feature corresponding to a first radiotherapy plan, wherein the first feature characterizes the distance information from each radiation source in the radiation field information of the first radiotherapy plan to each of N first organs; acquiring a second feature corresponding to a second radiotherapy plan, wherein the second feature characterizes the distance information from each radiation source in the radiation field information of the second radiotherapy plan to each of M second organs; and determining the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature. This application solves the technical problem in the prior art where the similarity of radiotherapy plans is compared solely based on image features, leading to inaccurate determination of the similarity.

Description

Technical Field

[0001] This application relates to the field of medical technology, and more specifically, to a method, apparatus, electronic device, and storage medium for determining the similarity of radiotherapy plans. Background Technology

[0002] In the field of medical technology, especially in the field of radiotherapy, it is often necessary to compare the similarity between two radiotherapy plans. For example, when evaluating a target radiotherapy plan for a target patient, it is necessary to compare the similarity between the target radiotherapy plan and the target patient's historical radiotherapy plans.

[0003] However, in existing technologies, when comparing the similarity of radiotherapy plans, the comparison is usually based solely on the image features of the medical images corresponding to the radiotherapy plans. This results in a lack of reference dimensions and information, leading to inaccurate determination of the similarity of radiotherapy plans.

[0004] There is currently no effective solution to the above problems. Summary of the Invention

[0005] This application provides a method, apparatus, electronic device, and storage medium for determining the similarity of radiotherapy plans, in order to at least solve the technical problem in the prior art where the similarity of radiotherapy plans is not accurately determined because the comparison is based solely on image features.

[0006] According to one aspect of this application, a method for determining the similarity of radiotherapy plans is provided, comprising: acquiring a first feature corresponding to a first radiotherapy plan, wherein the first feature is used to characterize the distance information from each radiation source in the radiation field information of the first radiotherapy plan to each of N first organs, the N first organs including the radiation target area of ​​the radiotherapy object corresponding to the first radiotherapy plan and at least one organ at risk; acquiring a second feature corresponding to a second radiotherapy plan, wherein the second feature is used to characterize the distance information from each radiation source in the radiation field information of the second radiotherapy plan to each of M second organs, the M second organs including the radiation target area of ​​the radiotherapy object corresponding to the second radiotherapy plan and at least one organ at risk; and determining the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature.

[0007] Optionally, the method for determining the similarity of radiotherapy plans further includes: obtaining a third feature corresponding to the first radiotherapy plan, wherein the third feature is the overlap volume histogram information of each radiation source to N first organs in the first radiotherapy plan; obtaining a fourth feature corresponding to the second radiotherapy plan, wherein the fourth feature is the overlap volume histogram information of each radiation source to M second organs in the second radiotherapy plan; and determining the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature, the second feature, the third feature, and the fourth feature.

[0008] Optionally, the method for determining the similarity of radiotherapy plans further includes: generating a first curve corresponding to the first radiotherapy plan based on the first feature and the third feature, wherein the first curve is a curve formed by the first feature as the abscissa and the third feature as the ordinate; generating a second curve corresponding to the second radiotherapy plan based on the second feature and the fourth feature, wherein the second curve is a curve formed by the second feature as the abscissa and the fourth feature as the ordinate; and determining the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first curve and the second curve.

[0009] Optionally, the method for determining the similarity of radiotherapy plans further includes: displaying the first curve and the second curve on the same coordinate system, and calculating the area of ​​the graph formed by the first curve and the second curve on the same coordinate system; determining the similarity between the first radiotherapy plan and the second radiotherapy plan based on the area of ​​the graph, wherein the area of ​​the graph and the similarity are negatively correlated.

[0010] Optionally, the method for determining the similarity of radiotherapy plans further includes: obtaining the position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system, wherein the resampling coordinate system is used to expand the horizontal plane size based on the medical image in the first radiotherapy plan; and determining a first feature based on the position coordinates and the delineation information corresponding to the first radiotherapy plan, wherein the delineation information is used to characterize the contour information of each of the N first organs in the medical image in the first radiotherapy plan.

[0011] Optionally, the method for determining the similarity of radiotherapy plans further includes: obtaining the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan, wherein the source axis distance corresponding to each radiation source is used to characterize the distance from the radiation source to the gantry rotation axis; and determining the position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system based on the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan.

[0012] Optionally, the method for determining the similarity of radiotherapy plans further includes: obtaining the position coordinates of each radiation source in the first radiotherapy plan on a first horizontal plane, wherein the first horizontal plane is a horizontal plane centered on the radiotherapy target area of ​​the radiotherapy object corresponding to the first radiotherapy plan; and determining the position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system based on the position coordinates of each radiation source in the first radiotherapy plan on the first horizontal plane, the field angle corresponding to each radiation source in the first radiotherapy plan, and the source axis distance.

[0013] According to another aspect of this application, a radiotherapy plan similarity determination apparatus is also provided, comprising: a first acquisition unit, configured to acquire a first feature corresponding to a first radiotherapy plan, wherein the first feature is used to characterize the distance information from each radiation source in the radiation field information of the first radiotherapy plan to each of N first organs, the N first organs including the radiation target area of ​​the radiotherapy object corresponding to the first radiotherapy plan and at least one organ at risk; a second acquisition unit, configured to acquire a second feature corresponding to a second radiotherapy plan, wherein the second feature is used to characterize the distance information from each radiation source in the radiation field information of the second radiotherapy plan to each of M second organs, the M second organs including the radiation target area of ​​the radiotherapy object corresponding to the second radiotherapy plan and at least one organ at risk; and a determination unit, configured to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature.

[0014] According to another aspect of this application, a computer-readable storage medium is also provided, wherein a computer program is stored in the computer-readable storage medium, wherein the similarity determination method for radiotherapy plans of any of the above-mentioned methods is controlled by the computer program when it is running to control the device where the computer-readable storage medium is located to execute the radiotherapy plan.

[0015] According to another aspect of this application, an electronic device is also provided, wherein the electronic device includes one or more processors and a memory for storing one or more programs, wherein when the one or more programs are executed by the one or more processors, the one or more processors implement the radiotherapy plan similarity determination method of any of the above.

[0016] In this application, the similarity of radiotherapy plans is determined by comparing the distance information from the radiation source to the radiation target area and organs at risk. First, a first feature corresponding to the first radiotherapy plan and a second feature corresponding to the second radiotherapy plan are obtained. Then, the similarity between the first and second radiotherapy plans is determined based on the first and second features. Specifically, the first feature characterizes the distance information from each radiation source in the radiation field information of the first radiotherapy plan to each of N first organs, where the N first organs include the radiation target area of ​​the radiotherapy subject corresponding to the first radiotherapy plan and at least one organ at risk. The second feature characterizes the distance information from each radiation source in the radiation field information of the second radiotherapy plan to each of M second organs, where the M second organs include the radiation target area of ​​the radiotherapy subject corresponding to the second radiotherapy plan and at least one organ at risk.

[0017] As can be seen from the above, unlike the existing technology that determines the similarity of radiotherapy plans solely through image features corresponding to the radiotherapy plan, this application determines the similarity of radiotherapy plans based on the distance information from the radiation source to the radiotherapy target area and the organs at risk. In contrast, image features can usually only characterize the delineation information of the radiotherapy target area and the organs at risk, and cannot characterize other information. However, the distance information from the radiation source to the radiotherapy target area and the organs at risk can characterize not only the radiation field information, but also the relative positional relationship between the radiation source, the radiotherapy target area, and the organs at risk. At the same time, since the distance information between the radiation source and the radiotherapy target area and / or the organs at risk will be different for different shapes of radiotherapy target areas and / or organs at risk, the distance information from the radiation source to the radiotherapy target area and the organs at risk can actually also characterize the shape information of the radiotherapy target area and the organs at risk.

[0018] Therefore, compared with the prior art, the technical solution of this application can determine the similarity of radiotherapy plans from more reference dimensions, thereby improving the accuracy of radiotherapy plan similarity determination. This solves the technical problem in the prior art that the similarity of radiotherapy plans is not accurately determined when comparing them based solely on image features. Attached Figure Description

[0019] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, illustrate exemplary embodiments and are used to explain this application, but do not constitute an undue limitation of this application. In the drawings:

[0020] Figure 1 This is a flowchart of an optional method for determining the similarity of radiotherapy plans according to an embodiment of this application;

[0021] Figure 2 This is a schematic diagram of a curve generated based on distance information and overlapping volume histogram information according to an optional embodiment of this application;

[0022] Figure 3 This is a schematic diagram of a graphic composed of an optional first curve and a second curve according to an embodiment of this application;

[0023] Figure 4 This is a flowchart illustrating an optional method for determining the position coordinates of each radiation source in a first radiotherapy plan within a resampling coordinate system, according to an embodiment of this application.

[0024] Figure 5 This is an optional distance distribution map according to an embodiment of this application;

[0025] Figure 6 This is a schematic diagram illustrating a process for determining the similarity of radiotherapy plans according to an embodiment of this application;

[0026] Figure 7This is a schematic diagram of an optional radiotherapy plan similarity determination device according to an embodiment of this application. Detailed Implementation

[0027] To enable those skilled in the art to better understand the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present application, and not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative effort should fall within the scope of protection of the present application.

[0028] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this application described herein can be implemented in orders other than those illustrated or described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0029] It should also be noted that all relevant information (including but not limited to patient information) and data (including but not limited to data used for display and analysis) involved in this application are information and data authorized by the user or fully authorized by all parties. For example, this system has an interface with the relevant user or institution. Before obtaining relevant information, it needs to send an acquisition request to the aforementioned user or institution through the interface, and obtain the relevant information after receiving consent from the aforementioned user or institution.

[0030] The present application will be further described below with reference to various embodiments.

[0031] Example 1

[0032] According to an embodiment of this application, an embodiment of a method for determining the similarity of radiotherapy plans is provided. It should be noted that the steps shown in the flowchart in the accompanying drawings can be executed in a computer system such as a set of computer-executable instructions. Furthermore, although a logical order is shown in the flowchart, in some cases, the steps shown or described may be executed in a different order than that shown here.

[0033] Figure 1 This is a flowchart of an optional radiotherapy plan similarity determination method according to an embodiment of this application, such as... Figure 1 As shown, the method includes the following steps:

[0034] Step S101: Obtain the first feature corresponding to the first radiotherapy plan.

[0035] In step S101, the first feature is used to characterize the distance information from each radiation source to each of the N first organs in the radiation field information of the first radiotherapy plan. The N first organs include the radiotherapy target area of ​​the radiotherapy object corresponding to the first radiotherapy plan and at least one organ at risk.

[0036] Optionally, the radiation field information in the first radiotherapy plan includes at least one radiation source. For example, assuming the radiation field information in the first radiotherapy plan includes two radiation sources, radiation source A and radiation source B, the target area of ​​the radiotherapy subject corresponding to the first radiotherapy plan is target area PTV1, and at least one organ at risk of the radiotherapy subject corresponding to the first radiotherapy plan is OAR1 and OAR2, respectively. Based on this, the first feature corresponding to the first radiotherapy plan is used to characterize the distance information of radiation source A to target areas PTV1, OAR1, and OAR2, and the distance information of radiation source B to target areas PTV1, OAR1, and OAR2, respectively.

[0037] Step S102: Obtain the second feature corresponding to the second radiotherapy plan.

[0038] In step S102, the second feature is used to characterize the distance information from each radiation source in the radiation field information of the second radiotherapy plan to each of the M second organs, wherein the M second organs include the radiotherapy target area of ​​the radiotherapy object corresponding to the second radiotherapy plan and at least one organ at risk.

[0039] Optionally, the radiotherapy target corresponding to the first radiotherapy plan and the radiotherapy target corresponding to the second radiotherapy plan can be the same or different targets. Furthermore, the radiation field information defined in the second radiotherapy plan includes at least one radiation source. For example, suppose the radiation field information defined in the second radiotherapy plan also includes two radiation sources, namely radiation source C and radiation source D, the radiation target area of ​​the radiotherapy target corresponding to the second radiotherapy plan is target area PTV2, and at least one organ at risk of the radiotherapy target corresponding to the second radiotherapy plan is OAR3 and OAR4, respectively. Based on this, the second feature corresponding to the second radiotherapy plan is used to characterize the distance information of radiation source C to target areas PTV2, OAR3, and OAR4, respectively, and the distance information of radiation source D to target areas PTV2, OAR3, and OAR4, respectively.

[0040] Step S103: Determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature.

[0041] Optionally, since both the first feature and the second feature represent the distance information from the radiation source to the radiation target area and the organs at risk, comparing the similarity between the first feature and the second feature is equivalent to comparing the similarity between the distance information from the radiation source to the radiation target area and the organs at risk in the first radiotherapy plan and the second radiotherapy plan. If the similarity between the first feature and the second feature is high, it indicates that the similarity between the first radiotherapy plan and the second radiotherapy plan is high.

[0042] Based on the content of steps S101 to S103 above, it can be seen that in this application, the similarity of radiotherapy plans is determined by comparing the distance information from the radiation source to the radiotherapy target area and the organs at risk. First, a first feature corresponding to the first radiotherapy plan and a second feature corresponding to the second radiotherapy plan are obtained. Then, the similarity between the first radiotherapy plan and the second radiotherapy plan is determined based on the first feature and the second feature. Specifically, the first feature is used to characterize the distance information from each radiation source in the radiation field information of the first radiotherapy plan to each of the N first organs, where the N first organs include the radiotherapy target area of ​​the radiotherapy subject corresponding to the first radiotherapy plan and at least one organ at risk; the second feature is used to characterize the distance information from each radiation source in the radiation field information of the second radiotherapy plan to each of the M second organs, where the M second organs include the radiotherapy target area of ​​the radiotherapy subject corresponding to the second radiotherapy plan and at least one organ at risk.

[0043] As can be seen from the above, unlike the existing technology that determines the similarity of radiotherapy plans solely based on image features corresponding to the radiotherapy plan, this application determines the similarity of radiotherapy plans based on the distance information from the radiation source to the radiation target area and the organs at risk. Since image features typically only characterize the delineation information of the radiation target area and the organs at risk, and cannot characterize other information, the distance information from the radiation source to the radiation target area and the organs at risk can characterize not only the radiation field information, but also the relative positional relationship between the radiation source, the radiation target area, and the organs at risk. Furthermore, due to the different shapes of the radiation... The distance information between the target area and the organ at risk and the radiation source will also be different. Therefore, the distance information from the radiation source to the target area and the organ at risk can actually characterize the shape information of the target area and the organ at risk. It can be seen that, compared with the prior art, the technical solution of this application can determine the similarity of the radiotherapy plan from more reference dimensions, thereby improving the accuracy of the similarity determination of the radiotherapy plan. This solves the technical problem in the prior art that the similarity of the radiotherapy plan is not accurately determined because it is compared only based on image features.

[0044] In an optional embodiment, a radiotherapy plan similarity determination device can serve as the execution subject of the radiotherapy plan similarity determination method in the embodiments of this application. The radiotherapy plan similarity determination device can be a software system or an embedded system combining software and hardware.

[0045] In one optional embodiment, the radiotherapy plan similarity determination device can acquire a third feature corresponding to a first radiotherapy plan and a fourth feature corresponding to a second radiotherapy plan. The third feature is the overlap volume histogram information from each radiation source to N first organs in the first radiotherapy plan, and the fourth feature is the overlap volume histogram information from each radiation source to M second organs in the second radiotherapy plan. Finally, the radiotherapy plan similarity determination device determines the similarity between the first and second radiotherapy plans based on the first, second, third, and fourth features.

[0046] Optionally, the overlap volume histogram information of each radiation source to N first organs in the first radiotherapy plan can be statistical information on the distances of each radiation source relative to the N first organs, wherein the statistical information includes the intersection distance information of all distance information corresponding to the N first organs. Furthermore, the overlap volume histogram information of each radiation source to N first organs in the first radiotherapy plan can also include the spatial relationship between any two first organs, including but not limited to the spatial relationship between each organ at risk of the radiotherapy subject corresponding to the first radiotherapy plan and the radiotherapy target area, and the spatial relationship between different organs at risk of the radiotherapy subject corresponding to the first radiotherapy plan.

[0047] Correspondingly, the overlap volume histogram information of each radiation source to the M second organs in the second radiotherapy plan can be statistical information on the distances of each radiation source relative to the M second organs, wherein the statistical information on the distances includes the intersections of all distance information corresponding to the M second organs. Furthermore, the overlap volume histogram information of each radiation source to the M second organs in the second radiotherapy plan can also include the spatial relationships between any two second organs, including but not limited to the spatial relationships between each organ at risk of the radiotherapy subject corresponding to the second radiotherapy plan and the radiotherapy target area, and the spatial relationships between different organs at risk of the radiotherapy subject corresponding to the second radiotherapy plan.

[0048] In one optional embodiment, the radiotherapy plan similarity determination device can generate a first curve corresponding to a first radiotherapy plan based on a first feature and a third feature, and generate a second curve corresponding to a second radiotherapy plan based on a second feature and a fourth feature. The first curve is a curve plotted with the first feature as the abscissa and the third feature as the ordinate, and the second curve is a curve plotted with the second feature as the abscissa and the fourth feature as the ordinate. Finally, the radiotherapy plan similarity determination device determines the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first curve and the second curve.

[0049] Optionally, Figure 2This is a schematic diagram of a curve generated based on distance information and overlapping volume histogram information according to an optional embodiment of this application, such as... Figure 2 As shown, the horizontal axis of the curve represents the distance information from the radiation source to the radiation target area or organ at risk, such as r1, r2, and d. The vertical axis of the curve represents the overlapping volume histogram information of the radiation source to the radiation target area or organ at risk, that is, the statistical information of the distance of each radiation source relative to the radiation target area or organ at risk.

[0050] It should be noted that, Figure 2 The curves shown are merely examples, used to illustrate one representation of the first and / or second curves; therefore, Figure 2 The curve in the diagram can refer to either the first curve or the second curve, and the corresponding horizontal and vertical coordinates can be adaptively changed according to the actual situation.

[0051] In one optional embodiment, the radiotherapy plan similarity determination device can display the first curve and the second curve on the same coordinate system and calculate the area of ​​the graph formed by the first curve and the second curve on the same coordinate system. Subsequently, the radiotherapy plan similarity determination device determines the similarity between the first radiotherapy plan and the second radiotherapy plan based on the area of ​​the graph, wherein the area of ​​the graph and the similarity are negatively correlated.

[0052] Optionally, Figure 3 This is a schematic diagram of a graphic composed of an optional first curve and a second curve according to an embodiment of this application. It is readily understood that if the first curve and the second curve are completely identical, the two curves will completely overlap in the same coordinate system; if the first curve and the second curve have a high degree of similarity, the area of ​​the graphic composed of the two curves will be smaller. Based on this, this application determines the similarity between the first radiotherapy plan and the second radiotherapy plan by displaying the first curve and the second curve in the same coordinate system and calculating the area of ​​the graphic composed of the first curve and the second curve in the same coordinate system, thereby determining the similarity between the first radiotherapy plan and the second radiotherapy plan based on the area of ​​the graphic.

[0053] In one optional embodiment, to obtain the first feature corresponding to the first radiotherapy plan, the radiotherapy plan similarity determination device first obtains the position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system, wherein the resampling coordinate system is used to expand the horizontal plane size based on the medical image in the first radiotherapy plan. Then, the radiotherapy plan similarity determination device determines the first feature based on the position coordinates and the delineation information corresponding to the first radiotherapy plan, wherein the delineation information is used to characterize the contour information of each of the N first organs in the medical image in the first radiotherapy plan.

[0054] Optionally, by expanding the horizontal plane size based on the medical image in the first radiotherapy plan using a resampled coordinate system, it can be ensured that the position coordinates of each radiation source in the first radiotherapy plan can be accurately obtained, thus avoiding the problem that the position coordinates of some radiation sources cannot be directly determined due to the small horizontal plane size corresponding to the medical image.

[0055] In one alternative embodiment, Figure 4 This is a flowchart illustrating an optional method for determining the position coordinates of each radiation source in a first radiotherapy plan within a resampling coordinate system, according to an embodiment of this application. Figure 4 As shown, it includes the following steps:

[0056] Step S401: Obtain the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan, wherein the source axis distance corresponding to each radiation source is used to characterize the distance from the radiation source to the gantry rotation axis.

[0057] Optionally, the field angle can be expressed as θ, and the source axis distance can be expressed as D. SAD .

[0058] Step S402: Determine the position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system based on the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan.

[0059] Optionally, in step S402, the radiotherapy plan similarity determination device first obtains the position coordinates of each radiation source in the first radiotherapy plan on a first horizontal plane, wherein the first horizontal plane is a horizontal plane centered on the radiation target area of ​​the radiotherapy object corresponding to the first radiotherapy plan. Subsequently, the radiotherapy plan similarity determination device determines the position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system based on the position coordinates of each radiation source in the first radiotherapy plan on the first horizontal plane, the field angle corresponding to each radiation source in the first radiotherapy plan, and the source axis distance.

[0060] Optionally, the position coordinates of the radiation source on the first horizontal plane can be represented as (X... P Y P The position coordinates of the radioactive source in the resampling coordinate system can be represented as (X... S Y S ).

[0061] Formula (1) shows X S The calculation formula.

[0062] X S =X P +D SAD *sinθ (1)

[0063] Formula (2) shows YS The calculation formula.

[0064] Y S =Y P +D SAD *cosθ (2)

[0065] In an optional embodiment, after obtaining the position coordinates of the radiation source in the resampling coordinate system, it is also necessary to combine the delineation information corresponding to the first radiotherapy plan to determine the distance information (i.e., the first feature) from the radiation source to the radiotherapy target area and at least one organ at risk of the radiotherapy object corresponding to the first radiotherapy plan. For specific operations, please refer to the following formula (3).

[0066] M ROI =DistMap(P P )*C ROI (3)

[0067] In formula (3), P P =(X P Y P DistMap is a function used to generate a full distance distribution map around the radiation source, M. ROI The first feature characterizing the radioactive source (the first feature can be represented as a distance distribution map around the radioactive source), C ROI The delineation information corresponding to the first radiotherapy plan.

[0068] Optionally, Figure 5 This is an optional distance distribution map according to an embodiment of this application, such as... Figure 5 As shown, Figure 5 The PTV in the image represents the delineation image corresponding to the radiotherapy target area (i.e., the delineation information corresponding to the radiotherapy target area). Figure 5 In the image, OAR1 is the delineated image corresponding to organ at risk 1. Figure 5 The image shows the delineated image corresponding to Organ 2 at risk of OAR2. Furthermore, Figure 5 The arrows connecting the radiation source to PTV, OAR1, and OAR2 indicate the distance information between the radiation source and PTV, OAR1, and OAR2.

[0069] It should be noted that, Figure 5 After conversion, it can be generated Figure 2 ,in, Figure 2 yes Figure 5 The statistical form, i.e. Figure 2 exist Figure 5 In addition, it can also characterize the overlapping volume histogram information of the radiation source to the organs at risk and the radiation target area.

[0070] In an optional embodiment, in order to obtain the second feature corresponding to the second radiotherapy plan, the radiotherapy plan similarity determination device can obtain the position coordinates of each radiation source in the second radiotherapy plan in the resampling coordinate system, and determine the second feature based on the position coordinates and the delineation information corresponding to the second radiotherapy plan, wherein the delineation information is used to characterize the contour information of each of the M second organs in the medical image of the second radiotherapy plan.

[0071] The process of obtaining the position coordinates of each radiation source in the second radiotherapy plan in the resampling coordinate system includes: obtaining the field angle and source axis distance corresponding to each radiation source in the second radiotherapy plan, and determining the position coordinates of each radiation source in the second radiotherapy plan in the resampling coordinate system based on the field angle and source axis distance corresponding to each radiation source in the second radiotherapy plan.

[0072] Optionally, determining the position coordinates of each radiation source in the second radiotherapy plan in the resampling coordinate system based on the field angle and source axis distance corresponding to each radiation source in the second radiotherapy plan includes: obtaining the position coordinates of each radiation source in the second radiotherapy plan on a second horizontal plane, and determining the position coordinates of each radiation source in the second radiotherapy plan in the resampling coordinate system based on the position coordinates of each radiation source in the second radiotherapy plan on the second horizontal plane, the field angle corresponding to each radiation source in the second radiotherapy plan, and the source axis distance. The second horizontal plane is a horizontal plane centered on the radiotherapy target area of ​​the radiotherapy object corresponding to the second radiotherapy plan.

[0073] In one alternative embodiment, Figure 6 This is a schematic diagram illustrating a process for determining the similarity of radiotherapy plans according to an embodiment of this application, such as... Figure 6 As shown, firstly, a first curve corresponding to the first radiotherapy plan and a second curve corresponding to the second radiotherapy plan are generated. Then, the similarity between the first and second radiotherapy plans is determined by the area of ​​the graph formed by the first and second curves. Figure 6 The specific process for generating the first / second curve is also illustrated. First, the radiation field information of the radiotherapy plan (first or second plan) is read, including the number of fields and the field angle. Then, the position coordinates of the radiation source are determined on the resampling coordinate system. Based on the position coordinates, a distance distribution map from the radiation source to the ROI (organ at risk and / or radiation target area) is determined. By converting the distance distribution map into a statistical form, the first / second curve can be obtained.

[0074] As can be seen from the above, unlike the existing technology that determines the similarity of radiotherapy plans solely through image features corresponding to the radiotherapy plan, this application determines the similarity of radiotherapy plans based on the distance information from the radiation source to the radiotherapy target area and the organs at risk. In contrast, image features can usually only characterize the delineation information of the radiotherapy target area and the organs at risk, and cannot characterize other information. However, the distance information from the radiation source to the radiotherapy target area and the organs at risk can characterize not only the radiation field information, but also the relative positional relationship between the radiation source, the radiotherapy target area, and the organs at risk. At the same time, since the distance information between the radiation source and the radiotherapy target area and the organs at risk will be different for different shapes of radiotherapy target areas and organs at risk, the distance information from the radiation source to the radiotherapy target area and the organs at risk can actually also characterize the shape information of the radiotherapy target area and the organs at risk.

[0075] Therefore, compared with the prior art, the technical solution of this application can determine the similarity of radiotherapy plans from more reference dimensions, thereby improving the accuracy of radiotherapy plan similarity determination. This solves the technical problem in the prior art that the similarity of radiotherapy plans is not accurately determined when comparing them based solely on image features.

[0076] Example 2

[0077] According to an embodiment of this application, an embodiment of a radiotherapy plan similarity determination device is provided. Figure 7 This is a schematic diagram of an optional radiotherapy plan similarity determination device according to an embodiment of this application, as shown below. Figure 7 As shown, the radiotherapy plan similarity determination device includes: a first acquisition unit 701, a second acquisition unit 702, and a determination unit 703.

[0078] Optionally, the first acquisition unit 701 is used to acquire a first feature corresponding to the first radiotherapy plan, wherein the first feature is used to characterize the distance information from each radiation source in the radiation field information of the first radiotherapy plan to each of the N first organs, and the N first organs include the radiation target area of ​​the radiotherapy object corresponding to the first radiotherapy plan and at least one organ at risk; the second acquisition unit 702 is used to acquire a second feature corresponding to the second radiotherapy plan, wherein the second feature is used to characterize the distance information from each radiation source in the radiation field information of the second radiotherapy plan to each of the M second organs, and the M second organs include the radiation target area of ​​the radiotherapy object corresponding to the second radiotherapy plan and at least one organ at risk; the determination unit 703 is used to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature.

[0079] Optionally, the determining unit 703 includes: a first acquiring subunit, a second acquiring subunit, and a first determining subunit. The first acquiring subunit is used to acquire a third feature corresponding to the first radiotherapy plan, wherein the third feature is the overlap volume histogram information from each radiation source to N first organs in the first radiotherapy plan; the second acquiring subunit is used to acquire a fourth feature corresponding to the second radiotherapy plan, wherein the fourth feature is the overlap volume histogram information from each radiation source to M second organs in the second radiotherapy plan; and the first determining subunit is used to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature, the second feature, the third feature, and the fourth feature.

[0080] Optionally, the first determining subunit includes: a first generating module, a second generating module, and a first determining module. The first generating module is used to generate a first curve corresponding to the first radiotherapy plan based on a first feature and a third feature, wherein the first curve is a curve formed by plotting the first feature as the abscissa and the third feature as the ordinate; the second generating module is used to generate a second curve corresponding to the second radiotherapy plan based on a second feature and a fourth feature, wherein the second curve is a curve formed by plotting the second feature as the abscissa and the fourth feature as the ordinate; the first determining module is used to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first curve and the second curve.

[0081] Optionally, the first determining module includes: a calculation submodule and a first determining submodule. The calculation submodule is used to display the first curve and the second curve on the same coordinate system and calculate the area of ​​the graph formed by the first curve and the second curve on the same coordinate system; the first determining submodule is used to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the area of ​​the graph, wherein the area of ​​the graph and the similarity are negatively correlated.

[0082] Optionally, the first acquisition unit 701 includes: a third acquisition subunit and a second determination subunit. The third acquisition subunit is used to acquire the position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system, wherein the resampling coordinate system is used to expand the horizontal plane size based on the medical image in the first radiotherapy plan; the second determination subunit is used to determine a first feature based on the position coordinates and delineation information corresponding to the first radiotherapy plan, wherein the delineation information is used to characterize the contour information of each of the N first organs in the medical image of the first radiotherapy plan.

[0083] Optionally, the third acquisition subunit includes: a first acquisition module and a second determination module. The first acquisition module is used to acquire the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan, wherein the source axis distance corresponding to each radiation source is used to characterize the distance from the radiation source to the gantry rotation axis; the second determination module is used to determine the position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system based on the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan.

[0084] Optionally, the second determining module includes: a first acquiring submodule and a second determining submodule. The first acquiring submodule is used to acquire the position coordinates of each radiation source in the first radiotherapy plan on a first horizontal plane, wherein the first horizontal plane is a horizontal plane centered on the radiotherapy target area of ​​the radiotherapy object corresponding to the first radiotherapy plan; the second determining submodule is used to determine the position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system based on the position coordinates of each radiation source in the first radiotherapy plan on the first horizontal plane, the corresponding field angle of each radiation source in the first radiotherapy plan, and the source axis distance.

[0085] Example 3

[0086] According to another aspect of the embodiments of this application, a computer-readable storage medium is also provided, the computer-readable storage medium including a stored computer program, wherein, when the computer program is running, it controls the device where the computer-readable storage medium is located to execute the radiotherapy plan similarity determination method of any one of the above embodiments 1.

[0087] Example 4

[0088] According to another aspect of the embodiments of this application, an electronic device is also provided, including: a processor; and a memory for storing executable instructions of the processor; wherein the processor is configured to execute the radiotherapy plan similarity determination method of any one of the above embodiments 1 by executing the executable instructions.

[0089] The sequence numbers of the embodiments in this application are for descriptive purposes only and do not represent the superiority or inferiority of the embodiments.

[0090] In the above embodiments of this application, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions of other embodiments.

[0091] In the several embodiments provided in this application, it should be understood that the disclosed technical content can be implemented in other ways. The device embodiments described above are merely illustrative; for example, the division of units can be a logical functional division, and in actual implementation, there may be other division methods. For example, multiple units or components may be combined or integrated into another system, or some features may be ignored or not executed. Furthermore, the displayed or discussed mutual couplings, direct couplings, or communication connections may be through some interfaces; indirect couplings or communication connections between units or modules may be electrical or other forms.

[0092] The units described as separate components may or may not be physically separate. The components shown as units may or may not be physical units; that is, they may be located in one place or distributed across multiple units. Some or all of the units can be selected to achieve the purpose of this embodiment according to actual needs.

[0093] Furthermore, the functional units in the various embodiments of this application can be integrated into one processing unit, or each unit can exist physically separately, or two or more units can be integrated into one unit. The integrated unit can be implemented in hardware or as a software functional unit.

[0094] If the integrated unit is implemented as a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of this application, in essence, or the part that contributes to the prior art, or all or part of the technical solution, can be embodied in the form of a software product. This computer software product is stored in a storage medium and includes several instructions to cause a computer device (which may be a personal computer, server, or network device, etc.) to execute all or part of the steps of the methods of the various embodiments of this application. The aforementioned storage medium includes various media capable of storing program code, such as a USB flash drive, read-only memory (ROM), random access memory (RAM), portable hard drive, magnetic disk, or optical disk.

[0095] The above are merely preferred embodiments of this application. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of this application, and these improvements and modifications should also be considered within the scope of protection of this application.

Claims

1. A method for determining the similarity of radiotherapy plans, characterized in that, include: Obtain a first feature corresponding to the first radiotherapy plan, wherein the first feature is used to characterize the distance information from each radiation source to each of the N first organs in the radiation field information formulated in the first radiotherapy plan, wherein the N first organs include the radiation target area of ​​the radiotherapy object corresponding to the first radiotherapy plan and at least one organ at risk. Obtain a second feature corresponding to the second radiotherapy plan, wherein the second feature is used to characterize the distance information from each radiation source to each of the M second organs in the radiation field information formulated in the second radiotherapy plan, wherein the M second organs include the radiotherapy target area of ​​the radiotherapy object corresponding to the second radiotherapy plan and at least one organ at risk; Determining the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature includes: obtaining a third feature corresponding to the first radiotherapy plan, wherein the third feature is the overlap volume histogram information from each radiation source in the first radiotherapy plan to the N first organs; obtaining a fourth feature corresponding to the second radiotherapy plan, wherein the fourth feature is the overlap volume histogram information from each radiation source in the second radiotherapy plan to the M second organs; and generating a first curve corresponding to the first radiotherapy plan based on the first feature and the third feature, wherein the first curve is plotted with the first feature as the abscissa and the third feature as the ordinate. The curves formed by the first feature and the fourth feature are used to generate a second curve corresponding to the second radiotherapy plan. The second curve is a curve formed by the second feature as the abscissa and the fourth feature as the ordinate. The similarity between the first radiotherapy plan and the second radiotherapy plan is determined based on the first curve and the second curve. The first curve and the second curve are displayed on the same coordinate system, and the area of ​​the figure formed by the first curve and the second curve on the same coordinate system is calculated. The similarity between the first radiotherapy plan and the second radiotherapy plan is determined based on the area of ​​the figure, wherein the area of ​​the figure and the similarity are negatively correlated.

2. The method for determining the similarity of radiotherapy plans according to claim 1, characterized in that, Obtain the first feature corresponding to the first radiotherapy plan, including: Obtain the position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system, wherein the resampling coordinate system is used to expand the horizontal plane size based on the medical image in the first radiotherapy plan; The first feature is determined based on the location coordinates and the delineation information corresponding to the first radiotherapy plan, wherein the delineation information is used to characterize the contour information of each of the N first organs in the medical image of the first radiotherapy plan.

3. The method for determining the similarity of radiotherapy plans according to claim 2, characterized in that, Obtain the position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system, including: Obtain the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan, wherein the source axis distance corresponding to each radiation source is used to characterize the distance from the radiation source to the gantry rotation axis; The position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system are determined based on the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan.

4. The method for determining the similarity of radiotherapy plans according to claim 3, characterized in that, The position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system are determined based on the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan, including: Obtain the position coordinates of each radiation source in the first radiotherapy plan on a first horizontal plane, wherein the first horizontal plane is a horizontal plane centered on the radiotherapy target area of ​​the radiotherapy object corresponding to the first radiotherapy plan; The position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system are determined based on the position coordinates of each radiation source in the first radiotherapy plan on the first horizontal plane, the field angle corresponding to each radiation source in the first radiotherapy plan, and the source axis distance.

5. A device for determining the similarity of radiotherapy plans, characterized in that, include: The first acquisition unit is used to acquire a first feature corresponding to the first radiotherapy plan, wherein the first feature is used to characterize the distance information from each radiation source to each of the N first organs in the radiation field information formulated in the first radiotherapy plan, and the N first organs include the radiotherapy target area of ​​the radiotherapy object corresponding to the first radiotherapy plan and at least one organ at risk. The second acquisition unit is used to acquire the second feature corresponding to the second radiotherapy plan, wherein the second feature is used to characterize the distance information from each radiation source to each of the M second organs in the radiation field information formulated in the second radiotherapy plan, wherein the M second organs include the radiotherapy target area of ​​the radiotherapy object corresponding to the second radiotherapy plan and at least one organ at risk. A determining unit is configured to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature; The determining unit includes: a first acquisition subunit, configured to acquire a third feature corresponding to the first radiotherapy plan, wherein the third feature is the overlap volume histogram information from each radiation source in the first radiotherapy plan to the N first organs; a second acquisition subunit, configured to acquire a fourth feature corresponding to the second radiotherapy plan, wherein the fourth feature is the overlap volume histogram information from each radiation source in the second radiotherapy plan to the M second organs; and a first determining subunit, configured to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature, the second feature, the third feature, and the fourth feature. The first determining subunit includes: a first generating module, configured to generate a first curve corresponding to the first radiotherapy plan based on the first feature and the third feature, wherein the first curve is a curve formed by the first feature as the abscissa and the third feature as the ordinate; a second generating module, configured to generate a second curve corresponding to the second radiotherapy plan based on the second feature and the fourth feature, wherein the second curve is a curve formed by the second feature as the abscissa and the fourth feature as the ordinate; and a first determining module, configured to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first curve and the second curve. The first determining module includes: a calculation submodule, used to display the first curve and the second curve on the same coordinate system and calculate the area of ​​the figure formed by the first curve and the second curve on the same coordinate system; and a first determining submodule, used to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the area of ​​the figure, wherein the area of ​​the figure and the similarity are negatively correlated.

6. A computer-readable storage medium, characterized in that, The computer-readable storage medium stores a computer program, wherein, when the computer program is executed, it controls the device where the computer-readable storage medium is located to perform the radiotherapy plan similarity determination method according to any one of claims 1 to 4.

7. An electronic device, characterized in that, It includes one or more processors and a memory, the memory being used to store one or more programs, wherein when the one or more programs are executed by the one or more processors, the one or more processors cause the one or more processors to implement the radiotherapy plan similarity determination method of any one of claims 1 to 4.

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