Reconstruction method, device and equipment of pulsed steady-state CEST signal and storage medium

Abstract

The application relates to the technical field of magnetic resonance, and discloses a reconstruction method and device of a pulsed steady-state CEST signal, equipment and a storage medium. The method comprises the following steps: performing normalization processing on a first CEST signal and a second CEST signal to obtain an apparent Z spectrum signal; calculating the longitudinal relaxation rate of water; establishing a functional relationship between the apparent Z spectrum signal and a target parameter, wherein the target parameter comprises the longitudinal relaxation rate of water, the duty cycle of a pulsed radio frequency saturation pulse, the pulse duration and the relaxation delay time; obtaining a target Z spectrum signal according to the functional relationship; and performing quantitative analysis on the target Z spectrum signal. The steady-state Z spectrum signal under the condition that the pulse duration and the relaxation delay time are at the maximum limit value can be obtained as the target Z spectrum signal, and then the target CEST signal close to the ideal steady-state CEST signal can be obtained, the influence of the non-sufficiently long pulse duration and the relaxation delay time on the quantification of the CEST signal is reduced, and the CEST imaging capability of a clinical magnetic resonance imaging system is enhanced.

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