异吲哚啉酮化合物

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By binding isoindolinone compounds to the E3 ligase hydroxycerebroside, specific degradation of GSPT1 is achieved, overcoming the shortcomings of existing technologies in the treatment of solid tumors and neuroendocrine cancers, and demonstrating significant therapeutic effects on a variety of cancers.

CN117242060BActive Publication Date: 2026-07-17MONTE ROSA THERAPEUTICS INC

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Patent Information

Authority / Receiving Office: CN · China
Patent Type: Patents(China)
Current Assignee / Owner: MONTE ROSA THERAPEUTICS INC
Filing Date: 2022-01-13
Publication Date: 2026-07-17

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Abstract

本文公开了式(I)的化合物或其药学上可接受的盐或立体异构体。这些化合物可用作羟脑苷脂的调节剂，特别是用于治疗哺乳动物体内，尤其人体内的异常细胞生长。

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