A photosensitizer based on mitochondrial copper depletion enhances light-induced ferroptosis of cells and synthesis and application thereof

Abstract

The application discloses a photosensitizer based on mitochondrial copper depletion for enhancing light-induced cell ferroptosis and synthesis and application thereof. The photosensitizer based on mitochondrial copper depletion for enhancing light-induced cell ferroptosis has the chemical structural formula as shown in the following formula: the photosensitizer based on mitochondrial copper depletion for enhancing light-induced cell ferroptosis and synthesis and application thereof, the dye can improve the ability of the photosensitizer to promote cell ferroptosis by depleting copper ions in mitochondria, has the functions of mitochondrial copper depletion and active oxygen generation, and effectively induces cell ferroptosis under light.

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