Application of OLA1 in the treatment of ocular vascular abnormalities

By using the drugs prepared by OLA1 protein in the treatment of ophthalmic diseases, the rebirth of blood vessels in the retina and cornea is suppressed, and the problem of limitations in the treatment methods of ophthalmic diseases in the prior art is solved, effective inhibition of abnormal vascular proliferative diseases in the eyes is achieved, and complications of surgical treatment are reduced.

CN117398448BActive Publication Date: 2025-03-28NANTONG UNIV
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Patent Information

Application Number
CN202311227321.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-09-22
Publication Date
2025-03-28
Estimated Expiration
2043-09-22

AI Technical Summary

Technical Problem

The treatment methods for ophthalmic diseases in the prior art are relatively limited, and surgical treatment is often used, and most of them are accompanied by complications such as intraocular infection, which brings great inconvenience to patients' lives.

Method used

Using OLA1 protein in the preparation of drugs for treating abnormal vascular proliferation in the ocular vascular disease, provides a new therapeutic strategy by inhibiting the regeneration of blood vessels in the retina and cornea.

Benefits of technology

Through in vivo experiments, OLA1 has an inhibitory effect on abnormal vascular hyperplasia in the retina and cornea, providing a new treatment strategy for clinical abnormal vascular hyperplasia in the ocular and reduces the complications caused by surgical treatment.

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Abstract

The present invention provides an application of OLA1 in treating ocular vascular abnormal proliferation diseases, and relates to the field of biomedical technology, including an application of OLA1 in preparing a drug for treating ocular vascular abnormal proliferation diseases. In the present application, in vivo and in vitro experiments verify that OLA1 has an inhibitory effect on abnormal proliferation of blood vessels in the retina and cornea, and provides a treatment strategy for clinical ocular vascular abnormal proliferation diseases.
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