A water suspension containing bromofenoxamine and cyromazine, its preparation process and application

Abstract

The application provides a water suspension agent containing bromocyclenam and dimethyl carbate, the water suspension agent contains bromocyclenam, dimethyl carbate and modified xanthan gum, and is used for preventing and treating garlic maggot, onion maggot, citrus fruit fly, leek maggot, bitter gourd fruit fly and cucumber american spotted leafminer. The product has high suspension rate, stable performance, can be stored for a long time, and is not prone to phenomena such as caking and sedimentation; the problems that xanthan gum needs to be additionally added with bactericides and the stable performance is reduced after grinding are solved.

Description

Technical Field

[0001] This invention relates to the field of pesticide technology, and in particular to an aqueous suspension containing bromocyanamide and cyromazine, its preparation process, and its application. Background Technology

[0002] Pesticide formulations refer to the forms in which pesticide active ingredients are prepared for practical use after the addition of appropriate adjuvants. This processing can improve the stability and biological activity of pesticide active ingredients, expand their application methods and uses, control the release rate of the active ingredients, and reduce pesticide toxicity, among other benefits.

[0003] Aqueous suspensions of pesticides are dispersions of water-insoluble solid pesticides in water. They refer to pesticide formulations prepared using water as the dispersion medium, comprising the active ingredient, wetting and dispersing agents, thickeners, stabilizers, pH adjusters, and defoamers. This formulation has the following advantages:

[0004] (1) Water-based, with good environmental compatibility; (2) Small particles, high suspension rate; (3) Low cost, water-based, with virtually no organic solvents required; (4) Safe processing. Pesticide water suspensions use water as a base and are processed using a wet method, eliminating dust generated during production (similar to wettable powders); (5) Safe and convenient to use. Pesticide water suspensions can be diluted with water and sprayed directly, or used for low-volume spraying on the ground or from aircraft. There is no dust generation or toxic solvent odor during use, which is beneficial to the health and safety of users.

[0005] Water-based suspension systems are kinetically unstable, therefore thickeners or stabilizers are often added to maintain a certain level of stability and suspension during storage or transportation. In water-based systems, xanthan gum, magnesium aluminum silicate, or organobentonite are often used as stabilizers, and xanthan gum and organobentonite are often compounded in routine production.

[0006] Xanthan gum's thickening effect decreases after grinding, but preparing it separately requires too much advanced equipment from the manufacturer. To address this issue, the present invention provides an aqueous suspension containing bromocyanamide and cyromazine. Summary of the Invention

[0007] This invention provides an aqueous suspension containing bromocyanamide and cyromazine, wherein the aqueous suspension comprises bromocyanamide, cyromazine, and modified xanthan gum;

[0008] The weight ratio of bromocyanamide to cyromazine is 1:(7-11); and the modified xanthan gum is epoxy-modified xanthan gum.

[0009] In one embodiment of the present invention, the weight ratio of bromocyanamide and cyromazine is 1:9.

[0010] In one embodiment of the present invention, the epoxy-modified xanthan gum is a mixture of mono-epoxy-modified xanthan gum and bis-epoxy-modified xanthan gum.

[0011] In one embodiment of the present invention, the aqueous suspension further includes a dispersant, a wetting agent, a stabilizer, an antifoaming agent, and an antifreeze agent.

[0012] In one embodiment of the present invention, the dispersant comprises a polycarboxylate dispersant.

[0013] In one embodiment of the present invention, the wetting agent is an anionic surfactant.

[0014] The aqueous suspension containing bromocyanamide and cyromazine comprises, by mass percentage, 1-3% bromocyanamide, 1-27% cyromazine, 0.1-0.3% modified xanthan gum, 1-5% dispersant, 2-5% wetting agent, 0.1-1% stabilizer, 0.1-0.3% defoamer, 2-5% antifreeze agent, and water to make up the difference.

[0015] A process for preparing the aqueous suspension containing bromocyanamide and cyromazine, comprising the following steps:

[0016] The mixture of bromocyanamide, cyromazine, dispersant, 0.5 parts of wetting agent and 0.4 parts of water was processed by shearing and grinding to a particle size of less than 5 micrometers, and then filtered to obtain a concentrated water suspension and filtrate.

[0017] The remaining raw materials and filtrate are mixed and treated, and then mixed evenly with the concentrated water suspension. The mixture is then sheared and milled until it meets the requirements to obtain the suspension.

[0018] The use of an aqueous suspension containing bromocyanamide and cyromazine for the control of garlic maggots, onion maggots, citrus fruit flies, leek maggots, bitter melon fruit flies, and cucumber serpentine leafminers.

[0019] By adopting the above technical solution, the present invention has the following beneficial effects:

[0020] 1. The product has a high suspension rate, stable performance, and can be stored for a long time without easily clumping or sedimentation.

[0021] 2. This addresses the issues of needing to add bactericides to xanthan gum and the reduced stability after grinding. Detailed Implementation

[0022] The technical solution of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0023] This invention provides an aqueous suspension containing bromocyanamide and cyromazine, wherein the aqueous suspension comprises bromocyanamide, cyromazine, and modified xanthan gum;

[0024] The weight ratio of bromocyanamide to cyromazine is 1:(7-11); and the modified xanthan gum is epoxy-modified xanthan gum.

[0025] bromocyanamide

[0026] Bromnipotentiamide is the second benzamide insecticide and the first multi-spectrum insecticide that can control not only chewing insects but also piercing-sucking, rasping-sucking, and sponging insects. Bromnipotentiamide provides excellent protection for stems, leaves, and fruits by controlling major pests such as whiteflies, aphids, thrips, psyllids, leaf miners, beetles, weevils, and lepidopteran larvae.

[0027] When cyantraniliprole is absorbed into insects, it forces the release of most of the calcium ions from the insect cells, causing a severe imbalance of calcium ions inside and outside the cells. Most of the calcium ions migrate into the insect's muscle tissue. Once these calcium ions effectively bind to troponin, they trigger contraction of actin and myosin over time, ultimately leading to muscle fiber contraction. Furthermore, during the release of calcium ions, numerous calcium ion pumps are activated, and most of the intracellular calcium ion flow exhibits a significantly irreversible characteristic. As the amount of calcium ion loss continues to increase, the insect's muscles remain in a contracted state for an extended period, leading to symptoms such as inability to eat, dehydration, and vomiting, ultimately resulting in death due to excessive muscle contraction.

[0028] Flymethrin

[0029] Cyromazine is a low-toxicity insecticide belonging to the insect growth regulator class. It has very strong selectivity, primarily active against Diptera insects. Its mechanism of action involves causing morphological abnormalities in Diptera larvae and pupae, resulting in incomplete or inhibited adult emergence. This pesticide has contact and stomach poison effects, strong systemic conductivity, and a long residual effect, but its rate of action is relatively slow. Cyromazine has no toxic side effects on humans or livestock and is environmentally safe.

[0030] The method for using an aqueous suspension containing bromocyanamide and cyromazine, wherein the aqueous suspension comprises, by mass percentage, 1-3% bromocyanamide, 1-27% cyromazine, 0.1-0.3% modified xanthan gum, 1-5% dispersant, 2-5% wetting agent, 0.1-1% stabilizer, 0.1-0.3% defoamer, 2-5% antifreeze agent, and water to make up the difference.

[0031] Modified xanthan gum

[0032] Xanthan gum is a typical microbial gum with excellent stability and rheological properties. The main chain and side chains of xanthan gum solution can form a rigid, ordered rod-shaped double helix structure through hydrogen bonding. At the same time, this double helix structure can also form a regular network structure depending on weak nonpolar covalent bond forces.

[0033] Xanthan gum solutions exhibit excellent salt, acid, and alkali resistance, properties attributed to the formation of dimers and double helix structures within them. Xanthan gum is a non-gelling polysaccharide that exhibits a highly significant synergistic gelling effect when used in combination with galactomannan. The smooth, unbranched molecular segments of galactomannan intertwine with xanthan gum molecular segments through hydrogen bonds and van der Waals forces, forming a three-dimensional network structure. This significantly increases the viscosity of the system, allowing it to gel under certain conditions.

[0034] In the preparation of suspensions, the raw materials need to be ground in a mill. However, when xanthan gum is ground, chain breakage occurs, leading to reduced product stability. Furthermore, xanthan gum can cause uneven mixing during the subsequent overall solution stirring process. Additionally, xanthan gum is prone to deterioration, therefore preservatives need to be added to prevent product instability.

[0035] To address this issue, the present invention provides a modified xanthan gum that can solve the aforementioned problems. Specifically, the modified xanthan gum is epoxy-modified xanthan gum.

[0036] The epoxy-modified xanthan gum is a mixture of mono-epoxy-modified xanthan gum and bis-epoxy-modified xanthan gum; and the mass ratio of the mono-epoxy-modified xanthan gum to the bis-epoxy-modified xanthan gum is 9:1.

[0037] The preparation method of the epoxy-modified xanthan gum is as follows: xanthan gum and water are mixed and stirred evenly, and then an alkaline solution is added to adjust the pH value to alkaline; then epoxy raw materials are added dropwise under stirring; after the addition is completed, the temperature is raised and the reaction is stirred; then epoxy-modified xanthan gum is precipitated, washed and dried to obtain epoxy-modified xanthan gum.

[0038] The epoxy raw material for the monoepoxy modified xanthan gum is monoepoxy glycidyl ether, and the monoepoxy glycidyl ether accounts for 8.5 wt% of the xanthan gum mass; the epoxy raw material for the bisepoxy modified xanthan gum is bisepoxy glycidyl ether, and the bisepoxy glycidyl ether accounts for 5 wt% of the xanthan gum mass; the alkaline solution is a 1 mol·L⁻¹ sodium hydroxide solution; the pH value is approximately 10; the reaction temperature is 45℃; and the reaction time is 5 h.

[0039] dispersant

[0040] A dispersant is a substance that can reduce the aggregation of solid (or liquid) particles in a dispersion system. In this invention, the dispersant comprises a polycarboxylate dispersant, specifically selected from Huntsman's TERSPERSE 2700.

[0041] In one embodiment of the present invention, the dispersant further includes a block copolymer dispersant, specifically Nouryon's Ethylan NS-500LQ.

[0042] In a preferred embodiment of the present invention, the ratio of TERSPERSE 2700 to Ethylan NS-500LQ is 4:1.

[0043] wetting agent

[0044] Wetting agents are substances that make solid materials easier to wet with water. They wet the solid material by reducing its surface tension or interfacial tension, allowing water to spread on or penetrate its surface.

[0045] From the perspective of product stability, the wetting agent is selected from anionic surfactants because the active ingredients used in this invention are bromocyanamide and cyromazine. When preparing an aqueous suspension, the wetting agent and dispersant will preferentially encapsulate the active ingredients, forming a protective layer around them, thereby achieving high dispersibility and suspension rate.

[0046] This invention uses polycarboxylate dispersants, which form carboxylate ions in water. After adsorbing onto the surface of the original drug ions, the surface becomes negatively charged, thereby attracting more anti-ion ions, enhancing the electrostatic repulsion between dispersed particles, and thus improving the dispersion stability of the system.

[0047] Using nonionic or cationic surfactants will disrupt the stability of polycarboxylate dispersants, thus reducing the system's storage performance.

[0048] Meanwhile, considering that the particle size of each particle in the aqueous suspension is actually different, it can only reach a certain range of particle size by averaging the particle size. At the same time, if the chain length of the dispersant is not suitable, it will destroy the original good dispersion effect. Therefore, in order to avoid such a phenomenon, the anionic surfactant in this invention is selected from tristyrene phenol phosphate, specifically Nouryon's Agrilan 1015.

[0049] stabilizer

[0050] In this invention, the stabilizer is magnesium aluminum silicate, specifically SF-04 from Suzhou Guojian Huitou Mineral New Materials.

[0051] Defoamer

[0052] The defoamer used in this invention is SAG1572 from Momentive Advanced Materials Group.

[0053] antifreeze

[0054] In this invention, the antifreeze agent is glycerol.

[0055] A process for preparing the aqueous suspension containing bromocyanamide and cyromazine, comprising the following steps:

[0056] The mixture of bromocyanamide, cyromazine, dispersant, 0.5 parts of wetting agent and 0.4 parts of water was processed by shearing and grinding to a particle size of less than 5 micrometers, and then filtered to obtain a concentrated water suspension and filtrate.

[0057] The remaining raw materials and filtrate were mixed and treated, and then mixed evenly with the concentrated water suspension. The mixture was sheared and milled until it met the requirements. The milling time was 2 hours and the speed was 1200 rpm to obtain the suspension.

[0058] The use of an aqueous suspension containing bromocyanamide and cyromazine for the control of garlic maggots, onion maggots, citrus fruit flies, leek maggots, bitter melon fruit flies, and cucumber serpentine leafminers.

[0059] The present invention will be further explained below with reference to specific embodiments.

[0060] Example:

[0061] Example 1: This example provides an aqueous suspension containing bromocyanamide and cyromazine. By mass percentage, the aqueous suspension includes 3% bromocyanamide, 27% cyromazine, 0.15% modified xanthan gum, 2% dispersant, 5% wetting agent, 1% stabilizer, 0.1% defoamer, 3% antifreeze agent, and water to make up the difference.

[0062] The epoxy-modified xanthan gum is a mixture of mono-epoxy-modified xanthan gum and bis-epoxy-modified xanthan gum; and the mass ratio of the mono-epoxy-modified xanthan gum to the bis-epoxy-modified xanthan gum is 9:1.

[0063] The preparation method of the epoxy-modified xanthan gum is as follows: Xanthan gum and water are mixed and stirred evenly, and then an alkaline solution is added to adjust the pH value to alkaline; then epoxy raw materials are added dropwise under stirring; after the addition is completed, the temperature is raised and the reaction is stirred; then epoxy-modified xanthan gum is precipitated, washed and dried to obtain epoxy-modified xanthan gum.

[0064] The epoxy raw material for the monoepoxy modified xanthan gum is monoepoxy glycidyl ether, and the monoepoxy glycidyl ether accounts for 8.5 wt% of the xanthan gum mass; the alkaline solution is a 1 mol·L⁻¹ sodium hydroxide solution with a pH of approximately 10; the reaction temperature is 45℃ and the reaction time is 5 h.

[0065] The epoxy raw material for the diepoxy-modified xanthan gum is diepoxy glycidyl ether, and the diepoxy glycidyl ether accounts for 5 wt% of the xanthan gum mass; the alkaline solution is a 1 mol·L⁻¹ sodium hydroxide solution; the pH value is about 10; the reaction temperature is 55℃ and the reaction time is 5.5 h.

[0066] The dispersant is TERSPERSE 2700 from Huntsman, USA, and Ethylan NS-500LQ from Norion, in a weight ratio of 4:1.

[0067] The wetting agent described in this embodiment is selected from tristyrylphenol phosphate, specifically Nouryon's Agrilan1015.

[0068] The stabilizer is magnesium aluminum silicate, specifically SF-04 from Suzhou Guojian Huitou Mineral New Materials.

[0069] In this embodiment, the defoamer is SAG1572 from Momentive Advanced Materials Group.

[0070] In this embodiment, the antifreeze is glycerol.

[0071] A process for preparing the aqueous suspension containing bromocyanamide and cyromazine, comprising the following steps:

[0072] The mixture of bromocyanamide, cyromazine, dispersant, 0.5 parts of wetting agent and 0.4 parts of water was processed by shearing and grinding to a particle size of less than 5 micrometers, and then filtered to obtain a concentrated water suspension and filtrate.

[0073] The remaining raw materials and filtrate were mixed and treated, and then mixed evenly with the concentrated water suspension. The mixture was sheared and milled until it met the requirements. The milling time was 2 hours and the speed was 1200 rpm to obtain the suspension.

[0074] Example 2:

[0075] This embodiment provides an aqueous suspension containing bromocyanamide and cyromazine. By mass percentage, the aqueous suspension includes 3% bromocyanamide, 27% cyromazine, 0.15% modified xanthan gum, 2% dispersant, 5% wetting agent, 1% stabilizer, 0.1% defoamer, 3% antifreeze agent, and water to make up the difference.

[0076] The epoxy-modified xanthan gum is a mixture of mono-epoxy-modified xanthan gum and bis-epoxy-modified xanthan gum; and the mass ratio of the mono-epoxy-modified xanthan gum to the bis-epoxy-modified xanthan gum is 9:1.

[0077] The preparation method of the epoxy-modified xanthan gum is as follows: Xanthan gum and water are mixed and stirred evenly, and then an alkaline solution is added to adjust the pH value to alkaline; then epoxy raw materials are added dropwise under stirring; after the addition is completed, the temperature is raised and the reaction is stirred; then epoxy-modified xanthan gum is precipitated, washed and dried to obtain epoxy-modified xanthan gum.

[0078] The epoxy raw material for the monoepoxy modified xanthan gum is monoepoxy glycidyl ether, and the monoepoxy glycidyl ether accounts for 8.5 wt% of the xanthan gum mass; the alkaline solution is a 1 mol·L⁻¹ sodium hydroxide solution with a pH of approximately 10; the reaction temperature is 45℃ and the reaction time is 5 h.

[0079] The epoxy raw material for the diepoxy-modified xanthan gum is diepoxy glycidyl ether, and the diepoxy glycidyl ether accounts for 5 wt% of the xanthan gum mass; the alkaline solution is a 1 mol·L⁻¹ sodium hydroxide solution; the pH value is about 10; the reaction temperature is 55℃ and the reaction time is 5.5 h.

[0080] The dispersant is TERSPERSE 2700 from Huntsman Corporation and Ethylan NS-500LQ from Norion, in a weight ratio of 4:1.

[0081] The wetting agent used in this embodiment is selected from Huntsman's Tersperse 4896.

[0082] The stabilizer is magnesium aluminum silicate, specifically SF-04 from Suzhou Guojian Huitou Mineral New Materials.

[0083] In this embodiment, the defoamer is SAG1572 from Momentive Advanced Materials Group.

[0084] In this embodiment, the antifreeze is glycerol.

[0085] A process for preparing the aqueous suspension containing bromocyanamide and cyromazine, comprising the following steps:

[0086] The mixture of bromocyanamide, cyromazine, dispersant, 0.5 parts of wetting agent and 0.4 parts of water was processed by shearing and grinding to a particle size of less than 5 micrometers, and then filtered to obtain a concentrated water suspension and filtrate.

[0087] The remaining raw materials and filtrate were mixed and treated, and then mixed evenly with the concentrated water suspension. The mixture was sheared and milled until it met the requirements. The milling time was 2 hours and the speed was 1200 rpm to obtain the suspension.

[0088] Example 3:

[0089] This embodiment provides an aqueous suspension containing bromocyanamide and cyromazine. By mass percentage, the aqueous suspension includes 3% bromocyanamide, 27% cyromazine, 0.15% modified xanthan gum, 2% dispersant, 5% wetting agent, 1% stabilizer, 0.1% defoamer, 3% antifreeze agent, and water to make up the difference.

[0090] The epoxy-modified xanthan gum is a mixture of mono-epoxy-modified xanthan gum and bis-epoxy-modified xanthan gum; and the mass ratio of the mono-epoxy-modified xanthan gum to the bis-epoxy-modified xanthan gum is 9:1.

[0091] The preparation method of the epoxy-modified xanthan gum is as follows: Xanthan gum and water are mixed and stirred evenly, and then an alkaline solution is added to adjust the pH value to alkaline; then epoxy raw materials are added dropwise under stirring; after the addition is completed, the temperature is raised and the reaction is stirred; then epoxy-modified xanthan gum is precipitated, washed and dried to obtain epoxy-modified xanthan gum.

[0092] The epoxy raw material for the monoepoxy modified xanthan gum is monoepoxy glycidyl ether, and the monoepoxy glycidyl ether accounts for 8.5 wt% of the xanthan gum mass; the alkaline solution is a 1 mol·L⁻¹ sodium hydroxide solution with a pH of approximately 10; the reaction temperature is 45℃ and the reaction time is 5 h.

[0093] The epoxy raw material for the diepoxy-modified xanthan gum is diepoxy glycidyl ether, and the diepoxy glycidyl ether accounts for 5 wt% of the xanthan gum mass; the alkaline solution is a 1 mol·L⁻¹ sodium hydroxide solution; the pH value is about 10; the reaction temperature is 55℃ and the reaction time is 5.5 h.

[0094] The dispersant is TERSPERSE 2700 from Huntsman, USA, and Ethylan NS-500LQ from Norion, in a weight ratio of 4:1.

[0095] The wetting agent described in this embodiment is calcium dodecylbenzenesulfonate.

[0096] The stabilizer is magnesium aluminum silicate, specifically SF-04 from Suzhou Guojian Huitou Mineral New Materials.

[0097] In this embodiment, the defoamer is SAG1572 from Momentive Advanced Materials Group.

[0098] In this embodiment, the antifreeze is glycerol.

[0099] A process for preparing the aqueous suspension containing bromocyanamide and cyromazine, comprising the following steps:

[0100] The mixture of bromocyanamide, cyromazine, dispersant, 0.5 parts of wetting agent and 0.4 parts of water was processed by shearing and grinding to a particle size of less than 5 micrometers, and then filtered to obtain a concentrated water suspension and filtrate.

[0101] The remaining raw materials and filtrate were mixed and treated, and then mixed evenly with the concentrated water suspension. The mixture was sheared and milled until it met the requirements. The milling time was 2 hours and the speed was 1200 rpm to obtain the suspension.

[0102] Example 4:

[0103] This embodiment provides an aqueous suspension containing bromocyanamide and cyromazine. By mass percentage, the aqueous suspension includes 3% bromocyanamide, 27% cyromazine, 0.15% modified xanthan gum, 2% dispersant, 5% wetting agent, 1% stabilizer, 0.1% defoamer, 3% antifreeze agent, and water to make up the difference.

[0104] The epoxy-modified xanthan gum is a monoepoxy-modified xanthan gum.

[0105] The preparation method of the epoxy-modified xanthan gum is as follows: Xanthan gum and water are mixed and stirred evenly, and then an alkaline solution is added to adjust the pH value to alkaline; then epoxy raw materials are added dropwise under stirring; after the addition is completed, the temperature is raised and the reaction is stirred; then epoxy-modified xanthan gum is precipitated, washed and dried to obtain epoxy-modified xanthan gum.

[0106] The epoxy raw material for the monoepoxy modified xanthan gum is monoepoxy glycidyl ether, and the monoepoxy glycidyl ether accounts for 8.5 wt% of the xanthan gum mass; the alkaline solution is a 1 mol·L⁻¹ sodium hydroxide solution with a pH of approximately 10; the reaction temperature is 45℃ and the reaction time is 5 h.

[0107] The dispersant is TERSPERSE 2700 from Huntsman, USA, and Ethylan NS-500LQ from Norion, in a weight ratio of 4:1.

[0108] The wetting agent described in this embodiment is selected from tristyrylphenol phosphate, specifically Nouryon's Agrilan1015.

[0109] The stabilizer is magnesium aluminum silicate, specifically SF-04 from Suzhou Guojian Huitou Mineral New Materials.

[0110] In this embodiment, the defoamer is SAG1572 from Momentive Advanced Materials Group.

[0111] In this embodiment, the antifreeze is glycerol.

[0112] A process for preparing the aqueous suspension containing bromocyanamide and cyromazine, comprising the following steps:

[0113] The mixture of bromocyanamide, cyromazine, dispersant, 0.5 parts of wetting agent and 0.4 parts of water was processed by shearing and grinding to a particle size of less than 5 micrometers, and then filtered to obtain a concentrated water suspension and filtrate.

[0114] The remaining raw materials and filtrate were mixed and treated, and then mixed evenly with the concentrated water suspension. The mixture was sheared and milled until it met the requirements. The milling time was 2 hours and the speed was 1200 rpm to obtain the suspension.

[0115] Example 5:

[0116] This embodiment provides an aqueous suspension containing bromocyanamide and cyromazine. By mass percentage, the aqueous suspension includes 3% bromocyanamide, 27% cyromazine, 0.15% modified xanthan gum, 2% dispersant, 5% wetting agent, 1% stabilizer, 0.1% defoamer, 3% antifreeze agent, and water to make up the difference.

[0117] The epoxy-modified xanthan gum is a double epoxy-modified xanthan gum.

[0118] The preparation method of the epoxy-modified xanthan gum is as follows: Xanthan gum and water are mixed and stirred evenly, and then an alkaline solution is added to adjust the pH value to alkaline; then epoxy raw materials are added dropwise under stirring; after the addition is completed, the temperature is raised and the reaction is stirred; then epoxy-modified xanthan gum is precipitated, washed and dried to obtain epoxy-modified xanthan gum.

[0119] The epoxy raw material for the diepoxy-modified xanthan gum is diepoxy glycidyl ether, and the diepoxy glycidyl ether accounts for 5 wt% of the xanthan gum mass; the alkaline solution is a 1 mol·L⁻¹ sodium hydroxide solution; the pH value is about 10; the reaction temperature is 55℃; and the reaction time is 5.5 h.

[0120] The dispersant is TERSPERSE 2700 from Huntsman, USA, and Ethylan NS-500LQ from Norion, in a weight ratio of 4:1.

[0121] The wetting agent described in this embodiment is selected from tristyrylphenol phosphate, specifically Nouryon's Agrilan1015.

[0122] The stabilizer is magnesium aluminum silicate, specifically SF-04 from Suzhou Guojian Huitou Mineral New Materials.

[0123] In this embodiment, the defoamer is SAG1572 from Momentive Advanced Materials Group.

[0124] In this embodiment, the antifreeze is glycerol.

[0125] A process for preparing the aqueous suspension containing bromocyanamide and cyromazine, comprising the following steps:

[0126] The mixture of bromocyanamide, cyromazine, dispersant, 0.5 parts of wetting agent and 0.4 parts of water was processed by shearing and grinding to a particle size of less than 5 micrometers, and then filtered to obtain a concentrated water suspension and filtrate.

[0127] The remaining raw materials and filtrate were mixed and treated, and then mixed evenly with the concentrated water suspension. The mixture was sheared and milled until it met the requirements. The milling time was 2 hours and the speed was 1200 rpm to obtain the suspension.

[0128] Example 6:

[0129] This embodiment provides an aqueous suspension containing bromocyanamide and cyromazine. By mass percentage, the aqueous suspension includes 3% bromocyanamide, 27% cyromazine, 0.15% xanthan gum, 2% dispersant, 5% wetting agent, 1% stabilizer, 0.1% defoamer, 3% antifreeze, and water to make up the difference.

[0130] The dispersant is TERSPERSE 2700 from Huntsman, USA, and Ethylan NS-500LQ from Norion, in a weight ratio of 4:1.

[0131] The wetting agent is selected from tristyrylphenol phosphate, specifically Nouryon's Agrilan 1015.

[0132] The stabilizer is magnesium aluminum silicate, specifically SF-04 from Suzhou Guojian Huitou Mineral New Materials.

[0133] In this embodiment, the defoamer is SAG1572 from Momentive Advanced Materials Group.

[0134] In this embodiment, the antifreeze is glycerol.

[0135] A process for preparing the aqueous suspension containing bromocyanamide and cyromazine, comprising the following steps:

[0136] The mixture of bromocyanamide, cyromazine, dispersant, 0.5 parts of wetting agent and 0.4 parts of water was processed by shearing and grinding to a particle size of less than 5 micrometers, and then filtered to obtain a concentrated water suspension and filtrate.

[0137] The remaining raw materials and filtrate were mixed and treated, and then mixed evenly with the concentrated water suspension. The mixture was sheared and milled until it met the requirements. The milling time was 2 hours and the speed was 1200 rpm to obtain the suspension.

[0138] Performance testing:

[0139] Suspension rate: GB / T14825-2006 Determination of Suspension Rate of Pesticides;

[0140] Low-temperature stability: 《GB / T 19137-2003 Method for Determination of Low-Temperature Stability of Pesticides》

[0141] Thermal storage stability: 《GB / T 19136-2003 Test Method for Thermal Storage Stability of Pesticides》

[0142] Dispersibility: Standards such as GB / T32775-2016 Determination of Dispersibility of Pesticides.

[0143] Table 1 Performance Test Results

[0144]

[0145] Example 7: The difference from Example 1 is that the dispersant does not contain TERSPERSE 2700 from Huntsman, USA.

[0146] During the preparation process, the viscosity increased during the grinding process in Examples 2 and 7, and the product became paste-like during storage. The above phenomena did not occur in the other examples.

[0147] Field efficacy test

[0148] Target leafminer flies in the tested crop, scallion.

[0149] Experimental site: Wumei Fruit Planting Cooperative, Juntian Village, Huaigao Town, Huaiyin District, Huai'an City, Jiangsu Province

[0150] For each plot, 10 plants were selected and 3 leaves infested with leaf miners were checked. The number of live leaf miners was recorded before and 3, 7, and 10 days after the application of the pesticide.

[0151] Table 2 Processing dosage

[0152]

[0153] Table 3. Number of leafminers infested with 3 leaves from 10 plants per plot before pesticide application: Count of live leafminers recorded before pesticide application.

[0154]

[0155] Table 4. Number of live insects recorded 3 days after medication.

[0156]

[0157] Table 5 shows the number of live insects recorded 7 days after medication.

[0158]

[0159] Table 6 shows the number of live insects recorded 10 days after medication.

[0160]

[0161] Table 7. Prevention and efficacy data

[0162]

[0163] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. An aqueous suspension containing bromocyanamide and cyromazine, characterized in that, The aqueous suspension comprises, by weight percentage, 3% bromocyanamide, 27% cyromazine, 0.15% epoxy-modified xanthan gum, 2% dispersant, 5% wetting agent, 1% stabilizer, 0.1% defoamer, 3% antifreeze, and water to make up the difference. The epoxy-modified xanthan gum is a mixture of mono-epoxy-modified xanthan gum and bis-epoxy-modified xanthan gum; and the mass ratio of the mono-epoxy-modified xanthan gum to the bis-epoxy-modified xanthan gum is 9:

1. The preparation method of the epoxy-modified xanthan gum is as follows: mix xanthan gum and water, stir evenly, and then add an alkaline solution to adjust the pH value to alkaline. Epoxy raw materials were then added dropwise under stirring; after the addition was complete, the temperature was increased and the mixture was stirred to react; epoxy-modified xanthan gum was then precipitated, and after washing and drying, epoxy-modified xanthan gum was obtained. The epoxy raw material for the monoepoxy modified xanthan gum is monoepoxy glycidyl ether, and the monoepoxy glycidyl ether accounts for 8.5 wt% of the xanthan gum mass. The alkaline solution is 1 mol·L⁻¹. -1 Sodium hydroxide solution; pH value around 10; reaction temperature 45℃; reaction time 5h; The epoxy raw material for the bis-epoxy modified xanthan gum is bis-epoxy glycidyl ether, and the bis-epoxy glycidyl ether accounts for 5 wt% of the xanthan gum mass; the alkaline solution is 1 mol·L⁻¹. -1 Sodium hydroxide solution; pH value around 10; reaction temperature 55℃; reaction time 5.5h; The dispersant is TERSPERSE 2700 from Huntsman, USA, and Ethylan NS-500LQ from Noryon, in a weight ratio of 4:1; The wetting agent is tristyrylphenol phosphate, specifically Nourion's Agrilan1015; The stabilizer is magnesium aluminum silicate, specifically SF-04 from Suzhou Guojian Huitou Mineral New Materials. The defoamer is SAG1572 from Momentive Advanced Materials Group. The antifreeze is glycerol.

2. A process for preparing the aqueous suspension containing bromocyanamide and cyromazine as described in claim 1, characterized in that, The process steps are as follows: The mixture of bromocyanamide, cyromazine, dispersant, 0.5 parts of wetting agent and 0.4 parts of water was processed by shearing and grinding to a particle size of less than 5 micrometers, and then filtered to obtain a concentrated water suspension and filtrate. The remaining raw materials and filtrate are mixed and treated, and then mixed evenly with the concentrated water suspension. The mixture is then sheared and milled until it meets the requirements to obtain the suspension.

3. The use of the aqueous suspension containing bromocyanamide and cyromazine as described in claim 1 for the control of garlic maggots, onion maggots, citrus fruit flies, leek maggots, bitter melon fruit flies, and cucumber serpentine leafminers.

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