Metabolic quality detection device based on standard air ventilation

By designing a metabolic quality control device based on standard gas ventilation, using an alcohol burner and solenoid valve to simulate human breathing, and combining a gas volume control unit and a control unit, the problem of inaccurate simulation in existing devices is solved, and accurate metabolic quality control is achieved.

CN117442188BActive Publication Date: 2026-08-04ZHONGKE (ANHUI) G60 SMART HEALTH INNOVATION RES INST
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHONGKE (ANHUI) G60 SMART HEALTH INNOVATION RES INST
Filing Date
2023-11-07
Publication Date
2026-08-04

AI Technical Summary

Technical Problem

Existing metabolic verification devices cannot accurately simulate human lung gas exchange, leading to measurement errors, especially errors from electronic measuring instruments that cannot meet the requirements for accurate detection.

Method used

Design a metabolic quality control device based on standard gas ventilation, including an alcohol burner, a standard gas cylinder, a solenoid valve, a gas volume control unit, and a control unit. The alcohol burner generates standard gas, which, combined with the solenoid valve and the gas volume control unit, simulates human respiration, avoiding errors in electronic measuring instruments and achieving precise gas supply and pressure compensation.

Benefits of technology

It improves the reliability and accuracy of metabolic quality testing devices, avoids errors caused by electronic measuring instruments, and can flexibly simulate different human breathing patterns to provide accurate quality testing results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application belongs to the field of energy metabolism and provides a metabolic quality detection device based on standard gas ventilation, which comprises a standard gas conveying unit, a gas constant volume unit, a breathing rate adjusting unit and a control unit; the standard gas conveying unit comprises an alcohol burner, a standard gas cylinder, an electromagnetic valve and a gas washing bottle; the gas constant volume unit comprises a T-shaped joint, a cylinder and a piston arranged in the cylinder; the alcohol burner is arranged to introduce an alcohol lamp quality detection mode, the standard gas cylinder is arranged to increase the diversity of the quality detection mode of the device, and the reliability of the device is increased; meanwhile, the electromagnetic valve is arranged to select a gas supply mode, thereby avoiding the calibration error caused by the monitoring of the electronic measuring components; in addition, the control unit and the gas constant volume unit can be flexibly arranged to simulate the breathing rate and perform real-time pressure compensation.
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Description

Technical Field

[0001] This invention belongs to the field of energy metabolism and provides a metabolic quality control device based on standard gas ventilation. Background Technology

[0002] With the continuous development of concepts such as science and technology, humanities, health, and environmental protection, indirect calorimetry instruments have shown tremendous demand in recent years in fields such as public health and clinical nutrition in China. However, due to the wide variety of indirect calorimetry instruments currently on the market, and the inconsistent performance and quality of these products, evaluation results vary when used for clinical testing and comparative analysis. Since the ultimate goal of indirect calorimetry instruments is to accurately detect the body's resting energy metabolism, quality control measures are essential. Therefore, for new indirect calorimetry instruments, quality control measures should be implemented before they enter clinical use and commercial applications. Because the instability of human respiration during the validation phase makes human testing methods unacceptable, the importance of metabolic quality control devices becomes apparent.

[0003] Current effective metabolic verification devices include the following types: First, static verification: the mixed gas released from the gas cylinder is injected into the gas collection circuit of the metabolic vehicle at a constant flow rate; second, dynamic verification: the mixed gas released from the gas cylinder is injected into the lung simulation device to simulate the periodic gas exchange in the human body.

[0004] However, existing static verification requires the gas in the cylinder to be introduced into the metabolic vehicle at a constant flow rate through a pressure regulator and a flow regulator, but it cannot simulate the cyclic movement of lung gas exchange. Existing dynamic verification can simulate the cyclic movement of lung gas exchange, but the electronic measuring instruments such as flow meters used have certain errors, which will lead to errors in the accuracy of theoretical analysis.

[0005] Therefore, this invention designs a metabolic quality inspection device based on standard gas ventilation to simulate human gas exchange in the lungs, which can be used for the research and development verification and production inspection of indirect human energy metabolism measuring instruments. Summary of the Invention

[0006] The purpose of this invention is to provide a metabolic quality control device based on standard gas ventilation, which aims to solve at least one of the problems mentioned in the background art.

[0007] The present invention is implemented as follows: a metabolic quality control device based on standard gas ventilation, the metabolic quality control device based on standard gas ventilation includes: a standard gas delivery unit, a gas volume control unit, a respiratory rate regulation unit and a control unit;

[0008] The standard gas delivery unit includes an alcohol burner, a standard gas cylinder, a solenoid valve, and a gas washing bottle. The first inlet of the solenoid valve is connected to the alcohol burner, and the second inlet is connected to the standard gas cylinder. The outlet of the solenoid valve is connected to a long tube that extends into the bottom of the gas washing bottle. A short tube is connected to the opening of the gas washing bottle. The alcohol burner generates and supplies the first standard gas to the solenoid valve, and the standard gas cylinder supplies the second standard gas to the solenoid valve. The solenoid valve controls the switching between the first and second standard gases, and the gas washing bottle can adjust the humidity and temperature of the first and second standard gases.

[0009] The gas volume control unit includes a T-connector, a cylinder, and a piston disposed in the cylinder. The piston is operatively connected to the breathing rate regulating unit. The first end of the T-connector is connected to the short tube via a conduit. The second end of the T-connector is connected to the cylinder via a conduit. The third end of the T-connector is connected to the gas path of the equipment to be inspected via a conduit. The first end of the T-connector is provided with a one-way valve that allows gas to flow into the T-connector, and the third end is provided with one-way valves that allow gas to flow out of the T-connector.

[0010] The control unit is used to control the operation of the breathing rate regulation unit and to control the pressure compensation of the gas in the catheter according to the real-time monitoring of the gas pressure in multiple catheters; the breathing rate regulation unit is used to drive the piston to reciprocate at a set rate and stroke so that the equipment to be inspected can detect the first standard gas or the second standard gas pumped out by the cylinder.

[0011] This invention provides a metabolic quality control device based on standard gas ventilation. By introducing an alcohol lamp quality control method through an alcohol burner and adding a standard gas cylinder, the device's quality control methods become more diverse, thereby increasing its reliability. At the same time, the use of a solenoid valve to select the gas supply method avoids calibration errors caused by using electronic measuring components for monitoring. Furthermore, the control unit and gas volume control unit can flexibly set the simulated breathing rate and perform real-time pressure compensation. Attached Figure Description

[0012] Figure 1 A schematic diagram of a metabolic quality control device based on standard gas ventilation provided in an embodiment of the present invention;

[0013] Figure 2 This is a partial structural schematic diagram of another metabolic quality control device based on standard gas ventilation provided in an embodiment of the present invention.

[0014] In the attached diagram: 1-Standard gas cylinder; 2-Pressure reducing valve; 3-Gas washing bottle; 4-One-way valve; 5-T-connector; 6-Cylinder; 7-Piston; 8-Bearing guide groove; 9-Straight connecting rod; 10-Strip opening; 11-Disc; 12-Fixed base; 13-Bearing; 14-Solenoid valve; 15-Alcohol burner; 16-Control unit; 17-Air pipeline; 18-Switch. Detailed Implementation

[0015] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the invention.

[0016] The specific implementation of the present invention will be described in detail below with reference to specific embodiments.

[0017] It is understood that the terms "first," "second," etc., used in this application may be used herein to describe various elements, but unless otherwise specified, these elements are not limited by these terms. These terms are used only to distinguish one element from another. For example, without departing from the scope of this application, a first standard gas may be referred to as a second standard gas, and similarly, a second standard gas may be referred to as a first standard gas.

[0018] like Figure 1 The diagram shown is a structural diagram of a metabolic quality control device based on standard gas ventilation provided in an embodiment of the present invention, including: a standard gas delivery unit, a gas volume control unit, a respiratory rate regulation unit, and a control unit;

[0019] The standard gas delivery unit includes an alcohol burner 15, a standard gas cylinder 1, a solenoid valve 14, and a gas washing bottle 3. The first inlet of the solenoid valve 14 is connected to the alcohol burner 14, and the second inlet is connected to the standard gas cylinder 1. The outlet of the solenoid valve 14 is connected to a long pipe that extends into the bottom of the gas washing bottle 3. A short pipe is connected to the opening of the gas washing bottle 3. The alcohol burner 15 is used to generate and supply the first standard gas to the solenoid valve 14. The standard gas cylinder 1 is used to supply the second standard gas to the solenoid valve 14. The solenoid valve 14 controls the switching between the first standard gas and the second standard gas. The gas washing bottle 3 can adjust the humidity and temperature of the first standard gas and the second standard gas.

[0020] The gas washing bottle 3 contains an appropriate amount of water. The mixed gas (such as the first standard gas, the second standard gas, or both) is discharged into the water through the long tube and then discharged through the short tube via the solenoid valve 14. This process is used to humidify the gas and can also cool the gas produced by the combustion of the alcohol burner 15, thereby more accurately simulating the state of the gas exhaled by the human body.

[0021] The gas volume control unit includes a T-connector 5, a cylinder 6, and a piston 7 disposed in the cylinder 6. The piston 7 is drivenly connected to the breathing rate regulating unit. The first end of the T-connector 5 is connected to the short tube through a conduit. The second end of the T-connector 5 is connected to the cylinder 6 through a conduit. The third end of the T-connector 5 is connected to the gas path of the equipment to be inspected through a conduit. The first end of the T-connector 5 is provided with a one-way valve 4 that allows gas to flow into the T-connector 5, and the third end is provided with a one-way valve 4 that allows gas to flow out of the T-connector 5.

[0022] The control unit 16 is used to control the operation of the breathing rate regulation unit and to control the pressure compensation of the gas in the catheter according to the real-time monitoring of the gas pressure in multiple catheters; the breathing rate regulation unit is used to drive the piston 6 to reciprocate at a set rate and stroke so that the equipment to be inspected can detect the first standard gas or the second standard gas pumped out by the cylinder 6.

[0023] In this embodiment, the metabolic quality control device based on standard gas ventilation introduces an alcohol lamp quality control method through the alcohol burner 15, and the addition of the standard gas cylinder 1 increases the diversity of the device's quality control methods, thereby increasing the reliability of the device. At the same time, the use of the solenoid valve 14 to select the gas supply method avoids calibration errors caused by using electronic measuring components for monitoring. In addition, the control unit 16 and the gas volume control unit can flexibly set the simulated breathing rate and perform real-time pressure compensation.

[0024] In one application scenario of this embodiment, the equipment to be inspected is a metabolic vehicle, a metabolic chamber, or other metabolic testing instrument that requires metabolic quality inspection. The use of standard gas cylinder 1 or alcohol burner 15 is separate. The second standard gas provided by standard gas cylinder 1 is a mixed gas with the same composition as air. Of course, the composition of the second standard gas provided will be slightly different depending on the standard gas cylinder 1 selected. In this way, different human respiration can be simulated. The composition of the first standard gas produced and provided by alcohol burner 15 can also be the same as that of air, and in some scenarios, the first and second standard gases are even the same gas. Compared with the quality inspection method using standard gas cylinder 1, alcohol combustion in alcohol burner 15 is another method for quality inspection of metabolic vehicles. The RQ value (respiratory quotient, defined as the ratio of carbon dioxide production to oxygen consumption at the same time) of alcohol combustion and the composition of the gas produced after alcohol combustion are known. More specifically, the theoretical RQ value and REE (Resting Energy Expenditure) are only related to the mass of alcohol consumed, the measurement time, and the alcohol combustion ratio. The theoretical RQ value is only related to the proportion of complete combustion of alcohol. Theoretically, the RQ value is the largest when alcohol is completely burned, and the lower the proportion of complete combustion of alcohol, the smaller the RQ value.

[0025] The chemical equation for the combustion of alcohol in air is known as follows:

[0026] C2H5OH + 3O2 = 2CO2 + 3H2O (complete combustion) (1);

[0027] C2H5OH + 2O2 = 2CO + 3H2O (partial incomplete combustion) (2);

[0028] C2H5OH+O2=2C+3H2O (complete but incomplete combustion) (3);

[0029] In other words, the amount and composition of the first standard gas used can be calibrated throughout the entire process of the alcohol burner 15 generating and supplying the first standard gas to the solenoid valve 14.

[0030] Similarly, the amount and composition of the second standard gas used can be calibrated throughout the entire process from the standard gas cylinder 1 supplying the second standard gas to the solenoid valve 14.

[0031] In one application scenario of this embodiment, when performing quality inspection on a metabolic vehicle using this standard gas-based metabolic quality inspection device, the device can be preheated. In this embodiment, the solenoid valve 14 effectively solves the problem of gas path selection. One inlet of the solenoid valve 14 is connected to the alcohol burner 15 via a conduit, and the other is connected to the pressure reducing valve 2 and the standard gas cylinder 1; gas exits from the same outlet. This increases the diversity of quality inspection methods and further improves the reliability of the device.

[0032] In one application scenario of this embodiment, the alcohol burner 15 includes an alcohol lamp and a sealed cover. The sealed cover can provide a constant volume of air for the alcohol lamp to burn, thereby enabling the first standard gas produced by the combustion of the alcohol lamp to be calibrated.

[0033] The selection of the standard gas cylinder 1 can be flexibly chosen according to the calibration values ​​of the metabolic vehicle requiring quality inspection; this embodiment does not impose any restrictions. The solenoid valve 14 can be an electrically controlled solenoid valve, which is controlled by the control unit 16. The electrically controlled solenoid valve has a common port, a normally closed port, and a normally open port, which correspond to the first inlet, second inlet, and outlet of the solenoid valve 14, respectively. The standard gas cylinder 1 itself has a valve to control the gas flow. The gas path is selected through the electrically controlled solenoid valve, i.e., the switching between the first standard gas and the second standard gas. One is the gas produced by the combustion of an alcohol lamp, and the other is the gas released from the standard gas cylinder 1; the composition of both gases is known.

[0034] like Figure 1As shown, in one embodiment, the control unit 16 can employ a human-machine interface module, which consists of a host, a display screen, and connecting lines. This allows the operator to conveniently and quickly modify various parameters (such as the reciprocating speed and stroke of the piston 7 in cylinder 6) and display the final data results on the human-machine interface (or display screen) when operating the device. For example, the breathing rate adjustment unit can be adjusted on the display screen, and the frequency and stroke of the piston 7 can be adjusted. Time and pressure monitoring functions can also be set, which can be implemented by programming on the host. Settings and observations can also be made in the software window of the human-machine interface. The solenoid valve can be controlled to select the gas path used and switch and control the on / off of the first standard gas and the second standard gas. Thus, the device does not use an electronic flow meter, solving the defect that the experimental data deviation caused by the error generated by the electronic flow meter test will affect the final result.

[0035] like Figure 1 As shown, in one usage scenario of this embodiment, the first end of the T-connector 5 is provided with a one-way valve 4 that allows gas to flow into the T-connector 5, and the third end is provided with a one-way valve 4 that allows gas to flow out of the T-connector 5.

[0036] Among them, the one-way valve 4 is used to control the gas flow direction. When the cylinder 6 draws in air, the one-way valve 4 on the right side of the T-connector 5 opens and the one-way valve 4 on the lower side closes. The gas in the standard gas cylinder 1, i.e. the second standard gas, enters the gas washing bottle 3 with an appropriate amount of water through the pressure reducing valve 2, and is then drawn into the cylinder 6. When the gas is exhausted, the one-way valve 4 on the lower side opens and the one-way valve 4 on the right side closes, and gas accumulates in the gas washing bottle 3.

[0037] In one application scenario of this embodiment, the control unit 16 can also be a programmable microcontroller, a PLC controller, or a microcontroller (MCU);

[0038] In one usage scenario of this embodiment, the control unit 16 is connected to a communication unit, which provides a mobile communication network, a near-field communication network, or a wireless communication local area network; the communication unit can be a conventional Bluetooth module, a near-field communication module, or a 5G network module, etc.

[0039] like Figure 1 As shown, in one usage scenario of this embodiment, the control unit 16 is connected to a pressure sensor. The pressure sensor is disposed at the first end and / or the third end of the T-connector to form a pressure compensation unit. The pressure compensation unit is used to compensate the pressure of the first standard gas or the second standard gas pumped to the equipment to be inspected.

[0040] In this embodiment, the pressure compensation unit is configured so that the control unit 16 monitors the pressure at the first and third ends of the T-connector 5 in real time through a pressure sensor, and adjusts the gas pressure delivered to the first end of the T-connector 5 according to the monitoring results. In practice, this can be adjusted by a valve installed on the conduit. This achieves the function of compensating for the gas pressure delivered to the third end of the T-connector 5. In this way, since the temperature and pressure of the gas change when it flows from the standard gas cylinder 1 through the pressure reducing valve 2, through the gas washing bottle 3, and through the one-way valve 4 to the cylinder 6, the situation where the gas measured by the metabolic vehicle is outside its measurement range can be avoided. This ensures that the first or second standard gas received by the metabolic vehicle during the measurement process is within the preset temperature and pressure standard range.

[0041] like Figure 2 As shown, in one embodiment, the pressure compensation unit further includes an air pipeline 17 and multiple air branches. One end of the air pipeline is connected to the end of the long pipe away from the gas washing bottle 3, and the other end of the air pipeline is connected to the first end of the T-connector 5 through multiple air branches arranged in parallel. A switch 18 is provided on some or all of the air branches to control the on / off state of the corresponding air branch.

[0042] In one application scenario of this embodiment, the multi-air branch is specifically configured with four branches. The four air branches are connected in parallel to the one-way valve 4 on the right side. By controlling the on / off state of one or more of them, the pressure of the gas delivered to the cylinder 6, and even the mass and flow rate of the gas, can be controlled, thereby achieving temperature and pressure compensation.

[0043] In one application scenario of this embodiment, multiple air branches can be set up with two, three, or even four or more. The specific number can be adjusted according to the pressure difference to compensate for the monitoring needs, as well as the applicable temperature and pressure range requirements of the metabolic vehicle. This embodiment provides several examples, but is not limited thereto.

[0044] Therefore, the temperature and humidity of the first or second standard gas delivered to the metabolic vehicle can be regulated or controlled via the gas washing bottle 3, and the temperature and pressure can be flexibly adjusted via the pressure compensation unit. This wide applicability better matches the calibration range of the metabolic vehicle, resulting in more accurate quality inspection results. Furthermore, it can work in conjunction with the breathing rate regulation unit, which converts circular motion into periodic motion, allowing for adjustment of the piston 7's stroke, pumping frequency, or speed. The gas temperature, pressure, humidity, and flow rate can all be flexibly adjusted, more realistically simulating human respiration and achieving precise quality inspection.

[0045] like Figure 1As shown, in one embodiment, the breathing rate regulating unit includes: a driver, a wheel 11, and a straight link 9;

[0046] The wheel 11 is mounted on the output shaft of the driver. The wheel 11 has a strip-shaped opening 10, and a pivot member with a variable position is provided in the strip-shaped opening 10. One end of the straight connecting rod 9 is connected to the pivot member, and the other end of the straight connecting rod 9 is connected to the piston 7. The driver drives the piston 7 to reciprocate at a set speed and stroke through the wheel 11 and the straight connecting rod 9. The set speed and stroke are selected according to the detection range of the metabolic vehicle, and only need to meet the temperature and pressure standards of the metabolic vehicle during the measurement process. No restrictions are imposed here.

[0047] In one usage scenario of this embodiment, the driver can be mounted on a workbench, which is provided with a fixed base 12. The wheel 11 is mounted on the fixed base 12 by a rolling bearing or a ball bearing and is fixedly connected to the output shaft of the driver.

[0048] The other end of the connecting rod 9 can be directly connected to the bearing 13 connected to the piston 7, or it can be connected to the piston 7 through a connecting rod or another connecting rod 9. For example, one end of a connecting rod 9 is connected to the piston 7, and the other end is connected to one end of another connecting rod 9 through a bearing 13. The other end of the other connecting rod 9 is connected to a pivot. In order to maintain the stability of the reciprocating motion of the piston 7, the connecting rod or connecting rod 9 connected to the piston 7 can be constrained by setting a bearing guide groove 8. That is, the connecting rod 9 is fixed in a horizontal position by the bearing guide groove 8.

[0049] In one application scenario of this embodiment, the pivot can be selected from bearing 13, bearing rod, hinge ball or rotating rod, etc., and the driver is a motor or electric motor, or even a stepper motor, pneumatic motor or other device with power output.

[0050] In one usage scenario of this embodiment, the wheel 11 has a mounting hole that passes through the strip-shaped opening 10. An adjusting screw is rotatably installed in the mounting hole. The adjusting screw is threadedly connected to a slider that slides with the strip-shaped opening 10. The slider is fixedly connected to the pivot member.

[0051] By adjusting the lead screw to change the position of the pivot in the strip opening 10 from the center, the stroke of the piston 7 in the cylinder 6 is adjusted during the process of converting the circular motion into a forward and backward periodic motion.

[0052] In another embodiment, the breathing rate regulating unit includes a telescopic member, the free end of which is rotatably connected to the piston 7, and the telescopic member drives the piston 7 to reciprocate at a set rate and stroke.

[0053] The telescopic component in this embodiment can be a pneumatic rod, a hydraulic rod, or an electromagnetic rod; the movement cycle of the telescopic component can be set and controlled by the control unit.

[0054] In one embodiment, the air duct 17 includes a first filter, an air tank, and a second filter. The inlet of the first filter is connected to the end of the long tube away from the gas washing bottle 3, the outlet of the first filter is connected to the inlet of the air tank, the outlet of the air tank is connected to the inlet of the second filter, and the outlet of the second filter is connected to multiple air branches arranged in parallel.

[0055] In one application scenario of this embodiment, the first filter element and the second filter element can be filters, and a solenoid valve is installed at the inlet or outlet end of the filter to control the gas flow rate.

[0056] In one embodiment, the control unit 16 is electrically connected to a timing unit and an alarm unit, so as to control the start and stop of the breathing rate regulation unit through the timing unit and to send out a reminder signal through the alarm unit.

[0057] Taking the control unit 16 as an example, when it is a host computer, the timing unit can be a timing clock installed in the memory integrated in the host computer; the alarm unit can be a general speaker or an alarm light.

[0058] In one embodiment, a temperature control element is provided inside the gas washing bottle 3. The temperature control element is electrically connected to the control unit 16, and the control unit 16 can maintain the water contained in the gas washing bottle 3 within a specified temperature range through the temperature control element.

[0059] The temperature control element is a heating wire; the temperature is maintained within a specified range, specifically 18-45℃.

[0060] Alternatively, the timing unit and alarm unit can be a timed reminder device; the timed reminder device incorporates a settable time length and an automatic reminder function in the software programming code; this function allows the operator to avoid constantly monitoring the device, saving time and preventing forgetting due to busyness, greatly increasing the controllability of the device.

[0061] This embodiment integrates the alcohol lamp quality inspection method into the device via the alcohol burner 15, improving the diversity of quality inspection methods and further enhancing the reliability of the device. The breathing rate regulation unit controlled by the control unit 16, in conjunction with the gas volume control unit, has a function of outputting metabolic gas with a fixed volume. The breathing rate and tidal volume can be set through the human-machine interface of the control unit 16 to meet different experimental needs. The timer can be set to meet different test time requirements, and an automatic alarm will be triggered when the time is up. The gas washing bottle 3 better simulates the humidity of exhaled gas. Therefore, this device has functions of volume control, breathing rate regulation, real-time pressure monitoring and compensation, as well as control of exhaust gas humidity and timer functions.

[0062] It is understandable that the concentrations of O2 and CO2 in the air inhaled by the human body are FiO2 and FiCO2, respectively. The concentrations of O2 and CO2 in the exhaled air are F... e O2 and F e CO2. Given that the amount of nitrogen remains constant during gas exchange in the human body, what is the volume of gas inhaled by the human body?

[0063] VI=VE(1-FeO2-FeCO2) / (1-FiO2-FiCO2), (using N2 for equilibrium) (4);

[0064] Carbon dioxide production: VCO2 = VE * F e CO2-VI*FiCO2

[0065] =VE*FeCO2-[VE(1-FeO2-FeCO2) / (1-FiO2-FiCO2)]*FiCO2

[0066] =VE*[FeCO2-FiCO2*(1-FeO2-FeCO2) / (1-FiO2-FiCO2)] (5);

[0067] Oxygen consumption: VO2 = VI * FiO2 - VE * F e O2

[0068] =[VE(1-FeO2-FeCO2) / (1-FiO2-FiCO2)]*FiO2-VE*FeO2

[0069] =VE*[FiO2*(1-FeO2-FeCO2) / (1-FiO2-FiCO2)-FeO2] (6);

[0070] RQ = Carbon dioxide production / Oxygen consumption (unit ml) (7).

[0071] In existing technologies, the specific calculation methods for simulating human gas metabolism, i.e., simulating the production of carbon dioxide and consumption of oxygen in the human body, can be found in existing technologies; for example... Figure 1 As shown, pulling piston 7 is equivalent to the "inhalation" process. The inhaled air has two sources: one part comes from a first standard gas with a fixed composition, and the other part comes from a second standard gas. The inhalation velocity of the first standard gas is f, and the inhalation velocity of the second standard gas is g. The CO2 concentration of the standard gases is x (the N2 concentration is 1-x). After being "inhaled," the gases from one or both sources mix in cylinder 6. As piston 7 pushes, the gases are "exhaled." Clearly, the exhalation velocity VE = f + g; the O2 and CO2 concentrations of the "inhaled" air are FiO2 and FiCO2, respectively, where FiCO2 is approximately 0; the O2 and CO2 concentrations of the "exhaled" gas are F... e O2 and F e CO2;

[0072] VE = f + g;

[0073] FeCO2=(f*x+g*FiCO2) / (f+g);

[0074] FeO2 = g * FiO2 / (f + g);

[0075] In this case, the amount of nitrogen inhaled and exhaled by the human body can be assumed to be constant, and the volume of gas inhaled by the human body can be calculated.

[0076] In another embodiment, a metabolic quality control method based on standard gas ventilation is provided for use with the apparatus described above, the method comprising:

[0077] First, the control unit 16 is turned on, and the required gas supply method, tidal volume, respiratory rate, and test time are selected. It is then connected to the gas circuit of the metabolic vehicle, and the device is started to preheat it.

[0078] By selecting the tidal volume and breathing rate, the drive adjusts the rotational speed of the wheel 11 and the stroke of the piston 7; the position of the pivot in the strip opening 10 can also be adjusted by sliding, and the circular motion is converted into periodic motion by the straight connecting rod 9, and the piston 7 connected thereto exhibits changes in stroke and pulling frequency.

[0079] When piston 7 draws air, the simulated human exhaled gas mixture is supplied by the selected gas supply method (first standard gas or second standard gas) through solenoid valve 14 into gas washing bottle 3 containing an appropriate amount of clean water. The water in the bottle can increase the gas humidity and reduce the gas temperature. Then, it flows through the conduit through one-way valve 4 and finally flows through cylinder 6.

[0080] During this process, the control unit 16 and pressure compensation unit monitor and compensate for the pressure of this gas section (the gas from solenoid valve 14 to cylinder 6) in real time to achieve the measurement standards required by the metabolic vehicle. During this process, the one-way valve 4 on the right side of the T-connector 5 is open, and the one-way valve 4 on the lower side is closed. When piston 7 exhausts, the mixed gas is discharged from cylinder 6 through the one-way valve 4 on the lower side of the T-connector 5, flowing into the gas path of the metabolic vehicle; at this time, the one-way valve 4 on the right side of the T-connector 6 is closed.

[0081] The above embodiments of the present invention provide a metabolic quality control device based on standard gas ventilation. The device incorporates an alcohol lamp for quality control via an alcohol burner 15, and the addition of a standard gas cylinder 1 increases the diversity of quality control methods, thereby enhancing the device's reliability. Simultaneously, a solenoid valve 14 selects the gas supply method, avoiding calibration errors caused by using electronic measuring components. Furthermore, the included gas washing bottle 3 can adjust the humidity of the gas output to the solenoid valve 14. The control unit 16 and gas volume control unit can flexibly set the simulated breathing rate and perform real-time pressure compensation.

[0082] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A metabolic substance measuring device based on standard air ventilation, characterized by, The metabolic quality control device based on standard gas ventilation includes: a standard gas delivery unit, a gas volume control unit, a respiratory rate regulation unit, and a control unit; The standard gas delivery unit includes an alcohol burner, a standard gas cylinder, a solenoid valve, and a gas washing bottle. The first inlet of the solenoid valve is connected to the alcohol burner, and the second inlet is connected to the standard gas cylinder. The outlet of the solenoid valve is connected to the long conduit of the gas washing bottle through a conduit extending to the bottom of the bottle. A short pipe is connected to the mouth of the gas washing bottle. The alcohol burner generates and supplies the first standard gas to the solenoid valve, and the standard gas cylinder supplies the second standard gas to the solenoid valve. The solenoid valve controls the switching between the first and second standard gases, and the gas washing bottle can adjust the humidity and temperature of the first and second standard gases. The gas volume control unit includes a T-connector, a cylinder, and a piston inside the cylinder. The piston is connected to the breathing rate regulating unit. The first end of the T-connector is connected to the short tube of the gas washing bottle through a conduit. The second end of the T-connector is connected to the cylinder through a conduit. The third end of the T-connector is connected to the gas path of the equipment to be inspected through a conduit. The first end of the T-connector is equipped with a one-way valve that allows gas to flow into the T-connector, and the third end is also equipped with a one-way valve that allows gas to flow out of the T-connector. The control unit is used to control the operation of the breathing rate regulation unit and to control the pressure compensation of the gas in the catheter according to the real-time monitoring of the gas pressure in multiple catheters; the breathing rate regulation unit is used to drive the piston to reciprocate at a set rate and stroke so that the equipment to be inspected can detect the first standard gas or the second standard gas discharged from the cylinder. The control unit is connected to a pressure sensor, which is disposed at the first and / or third end of the T-connector to form a pressure compensation unit. The pressure compensation unit is used to compensate for the pressure of the first or second standard gas pumped to the equipment to be inspected. The pressure compensation unit also includes an air pipeline and multiple air branches. One end of the air pipeline is connected to the end of the long conduit away from the gas washing bottle, and the other end of the air pipeline is connected to the first end of the T-connector through multiple air branches arranged in parallel. The air pipeline includes a first filter, an air storage tank, and a second filter. The air inlet of the first filter is connected to the end of the long conduit away from the gas washing bottle, the air outlet of the first filter is connected to the air inlet of the air storage tank, the air outlet of the air storage tank is connected to the air inlet of the second filter, and the air outlet of the second filter is connected to the multiple air branches arranged in parallel. A first pressure gauge or a first pressure transmitter is provided on the air storage tank to monitor the air pressure inside the air storage tank.

2. The standard gas ventilation based metabolic measurement device according to claim 1, characterized in that, The respiratory rate regulation unit includes: a driver, a wheel, and a direct link; The wheel is mounted on the output shaft of the driver. The wheel has a strip-shaped opening, and a pivot member with a variable position is arranged in the strip-shaped opening. One end of the straight connecting rod is connected to the pivot member, and the other end of the straight connecting rod is connected to the piston. The driver drives the piston to reciprocate at a set speed and stroke through the wheel and the straight connecting rod.

3. The standard gas ventilation based metabolic measurement device according to claim 2, characterized in that, The wheel has a mounting hole that passes through the strip-shaped opening. An adjusting screw is rotatably installed in the mounting hole. The adjusting screw is threadedly connected to a slider that slides with the strip-shaped opening. The slider is fixedly connected to the pivot.

4. The standard gas ventilation based metabolic measurement device according to claim 1, wherein, The breathing rate regulating unit includes a telescopic component, the free end of which is connected to the piston via a transmission connection, and the telescopic component drives the piston to reciprocate at a set rate and stroke.

5. The standard gas ventilation based metabolic measurement device according to claim 1, wherein, The alcohol burner includes an alcohol lamp and a sealed enclosure. The sealed enclosure can provide a constant volume of air for the alcohol lamp to burn, thereby enabling the first standard gas produced by the combustion of the alcohol lamp to be calibrated.

6. The standard gas ventilation based metabolic measurement device according to claim 1, wherein, The control unit is electrically connected to a timing unit and an alarm unit, so as to control the start and stop of the breathing rate regulation unit through the timing unit and to send out a reminder signal through the alarm unit.

7. The standard gas ventilation based metabolic measurement device according to claim 1, wherein, The gas washing bottle is equipped with a temperature control element, which is electrically connected to the control unit. The control unit can maintain the water in the gas washing bottle within a specified temperature range through the temperature control element.