A breast biopsy sampling collection cartridge with sample-in-place sensing functionality

Abstract

The application discloses a breast biopsy sampling collection bin with sample in-place sensing function, which is connected between a sampling device and a biopsy system host and used for storing biopsy samples, and comprises a shell, an inner cylinder and a plurality of collection tubes. The shell is connected with the sampling device, and an in-place sensing unit is arranged on the inner wall of the shell. The inner cylinder is embedded in the shell, one end of the collection tube is limited on the inner cylinder through a clamping plate and is provided with a negative pressure hole, the other end of the collection tube is inserted into a containing chamber and is provided with a sample inlet hole, and a sampling assembly is arranged on a sample wall. The breast biopsy sampling collection bin with the sample in-place sensing function is provided with a detection opening on the inner cylinder, and cooperates with the in-place sensing unit, so that whether the sample exists in the collection tube can be quickly sensed, the condition that multiple samples enter the same collection tube or no sample exists in the collection tube is prevented, and the sampling assembly is arranged on the collection tube, so that an operator can quickly take out the sample from the sampling port, and the operator is prevented from clamping out the sample from the narrow through holes at two ends.

Description

Technical Field

[0001] This invention relates to breast biopsy sampling technology, specifically a breast biopsy sampling collection chamber with sample arrival sensing function. Background Technology

[0002] The incidence of breast diseases is very high in my country. Clinically, many diseases, such as fibroadenomas, require surgical removal. However, surgical incisions are obvious, invasive, unsightly, and expensive. Currently, breast diseases can be diagnosed and treated using biopsy. Biopsy systems are often used to help patients determine whether the cells in the examined area are cancerous. Breast biopsy is a minimally invasive procedure performed under local anesthesia, without the need for general anesthesia or postoperative sutures. Only a very small skin incision (2mm) is needed to remove tissue for histological pathological examination and diagnosis. Typically, guided by ultrasound or other imaging techniques, the Mammotome biopsy probe is inserted through the skin to reach the target tumor. Under slight vacuum suction, the tissue is drawn into the collection groove of the biopsy probe and subjected to rotary cutting and sampling until the benign tumor in the breast is completely or partially removed. The removed breast tissue needs to be aspirated into a sample collection chamber for preservation.

[0003] Breast biopsies typically require multiple excisions. To prevent cross-contamination from storing multiple samples in the same collection chamber, existing sample collection chambers are usually divided into multiple collection tubes, with samples stored in different tubes. These tubes have through-holes at both ends to allow the system to apply negative pressure to draw the sample into the tube. However, this method cannot detect whether a sample has entered the tube, leading to situations where multiple samples end up in the same tube or a tube is empty. This makes subsequent sample classification difficult, affecting testing efficiency and accuracy. Furthermore, when retrieving samples from the collection chamber for testing, the operator must clamp them through the narrow through-holes at both ends, making the operation difficult and significantly impacting testing efficiency. Summary of the Invention

[0004] To address the shortcomings of the prior art, this invention provides a breast biopsy sampling collection chamber with a sample arrival sensing function. This chamber can perform sample arrival detection on a single collection tube, avoiding situations where multiple samples enter the same collection tube or where there is no sample in the collection tube. It also allows for convenient sample removal.

[0005] To achieve the above technical objectives, the present invention adopts the following technical solution: a breast biopsy sampling collection chamber with sample arrival sensing function, connected between the sampling device and the biopsy system host, for storing biopsy samples, including an outer shell, an inner cylinder and several collection tubes; the outer shell is connected to the sampling device, and a limiting groove is provided on the inner wall of the outer shell, with an arrival sensing unit fixed in the limiting groove; the inner cylinder is embedded in the outer shell, and the inner cylinder has circumferentially uniformly arranged receiving chambers, with a detection port corresponding to the arrival sensing unit on the side of the receiving chamber that is in contact with the inner wall of the outer shell, and a limiting ring is fixed on the outer periphery of the inner cylinder facing the sampling device, the limiting ring confining the inner cylinder within the outer shell, and a rotating shaft is fixed on the side of the inner cylinder facing the biopsy system host; one end of the collection tube is confined to the inner cylinder by a clamping plate and has a negative pressure hole, and the other end is inserted into the receiving chamber and has a sample inlet hole, the collection tube including a receiving cavity for receiving samples, a detection wall facing the detection port and a sampling wall relative to the detection port, the receiving cavity being located between the detection wall and the sampling wall, and a sampling component being provided on the sampling wall.

[0006] Preferably, the inner cylinder is provided with a sealing plate on the side facing the biopsy system host, and a pull rod is provided on the sealing plate.

[0007] Preferably, the outer casing is provided with a mounting cover on the side facing the sampling device, and the outer casing is fixed to the sampling device by the mounting cover.

[0008] Preferably, the inner wall of the outer shell is provided with two protrusions, which are respectively located on both sides of the limiting groove, and the detection port is provided with recesses that cooperate with the protrusions on both sides.

[0009] Preferably, the negative pressure hole is equipped with a grid.

[0010] Preferably, the sampling component includes a sampling port disposed on the sampling wall, a sampling plate being snapped onto the sampling port, and a clamping block being provided on the sampling plate.

[0011] Preferably, the position sensing unit includes an infrared sensor.

[0012] Preferably, the positioning sensing unit has slots on both sides, and the inner walls on both sides of the positioning slots have spring pieces that engage with the slots.

[0013] Preferably, the limiting groove is provided with a pressure plate, and the pressure plate is sealed to the groove wall by a sealing ring.

[0014] Preferably, the collecting tube and the pressure plate are made of transparent acrylic, and the position sensing unit, the pressure plate and the detection wall are arranged in parallel.

[0015] In summary, the present invention has achieved the following technical effects:

[0016] 1. The breast biopsy sampling collection chamber of the present invention with sample arrival sensing function has a detection port on the inner cylinder and is equipped with an arrival sensing unit to quickly sense whether there is a sample in the collection tube. This prompts the operator and the biopsy system host to rotate the inner cylinder and switch to the next collection tube for the next sample collection, preventing multiple samples from entering the same collection tube or the collection tube from being empty.

[0017] 2. The breast biopsy sampling collection chamber of the present invention with sample arrival sensing function has a sampling component set on the collection tube, which allows the operator to quickly take out the sample from the sampling port on the sampling wall, which is much larger than the sampling hole, avoiding the operator from pinching out the sample from the narrow through holes at both ends. The operation is convenient and greatly improves the detection efficiency.

[0018] 3. The breast biopsy sampling collection chamber of the present invention with sample arrival sensing function is equipped with a grid, which can keep the sample in the receiving cavity and prevent the sample from being sucked out of the collection tube. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the structure of a breast biopsy sampling collection chamber with sample arrival sensing function provided in an embodiment of the present invention;

[0020] Figure 2 yes Figure 1 Sectional view along axis AA;

[0021] Figure 3 yes Figure 2 Enlarged view of part B;

[0022] Figure 4 This is a schematic diagram of the collection tube of the breast biopsy sampling collection chamber with sample arrival sensing function provided in an embodiment of the present invention;

[0023] Explanation of reference numerals in the accompanying drawings: 1. Outer shell; 2. Inner cylinder; 3. Sealing plate; 4. Mounting cover; 5. Limiting ring; 6. Rotating shaft; 7. Receiving chamber; 8. Collection tube; 81. Detection wall; 82. Sampling wall; 83. Receiving cavity; 84. Clamping plate; 85. Grille; 86. Sampling port; 87. Sampling plate; 88. Clamping block; 9. Recess; 10. Protrusion; 11. Pull rod; 12. Position sensing unit; 13. Detection port; 14. Limiting groove; 15. Clamping groove; 16. Spring; 17. Sealing ring; 18. Pressure plate. Detailed Implementation

[0024] The present invention will be further described in detail below with reference to the accompanying drawings.

[0025] This specific embodiment is merely an explanation of the present invention and is not intended to limit the invention. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they are within the scope of the claims of the present invention.

[0026] In the description of this invention, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0027] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0028] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0029] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "over," and "on top" of the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0030] Example 1:

[0031] like Figure 1As shown in Figure 4, a breast biopsy sampling collection chamber with sample arrival sensing function is connected between the sampling device and the biopsy system host for storing biopsy samples. It includes an outer shell 1, an inner cylinder 2, and several collection tubes 8. The outer shell 1 is connected to the sampling device, and a limiting groove 14 is provided on the inner wall of the outer shell 1, within which an arrival sensing unit 12 is fixed. The inner cylinder 2 is embedded within the outer shell 1 and connected to the biopsy system host. The inner cylinder 2 has circumferentially evenly distributed receiving chambers 7. A detection port 13 corresponding to the arrival sensing unit 12 is provided on the side of the receiving chamber 7 that is in contact with the inner wall of the outer shell 1. The inner cylinder 2 facing the sampling device... A limiting ring 5 is fixed on the outer periphery, which limits the inner cylinder 2 within the outer shell 1. A rotating shaft 6 is fixed on the side of the inner cylinder 2 facing the biopsy system host. One end of the collection tube 8 is limited to the inner cylinder 2 by a clamping plate 84 and is provided with a negative pressure hole. The other end is inserted into the receiving chamber 7 and is provided with a sample inlet hole. The collection tube 8 includes a receiving cavity 83 for receiving samples, a detection wall 81 facing the detection port 13, and a sampling wall 82 relative to the detection port 13. The receiving cavity 83 is located between the detection wall 81 and the sampling wall 82. A sampling component is provided on the sampling wall 82. The position sensing unit is connected to the biopsy system host through a line channel in the outer shell 1.

[0032] To improve the sealing between the inner cylinder 2 and the biopsy system host, a sealing plate 3 is provided on the side of the inner cylinder 2 facing the biopsy system host, and a pull rod 11 is provided on the sealing plate 3; wherein the sealing plate 3 is provided with a groove that matches the protrusion on the inner wall of the outer shell 1, and an air passage is provided on the side of the sealing plate 3 facing the positioning sensing unit 12.

[0033] In order to fix the outer casing 1 to the sampling device and improve the sealing between the outer casing 1 and the sampling device, the outer casing 1 is provided with a mounting cover 4 facing the sampling device. The outer casing 1 is fixed to the sampling device through the mounting cover 4, and a sealing gasket is provided on the limiting ring 5. The inner wall of the mounting cover is provided with an internal thread that mates with the external thread of the end of the sampling device. Rotating the outer casing and the mounting cover fixes the outer casing to the sampling device. Alternatively, the mounting cover is provided with an L-shaped through groove, and the sampling device is provided with a locking pin that moves along the L-shaped through groove.

[0034] In order to ensure that the detection port 13 is directly aligned with the position sensing unit, and that the position sensing unit 12, the pressure plate 18, and the detection wall 81 are all arranged in parallel, so as to avoid the infrared light emitted by the sample or the light received by the position sensing unit 12 from decreasing in intensity due to refraction and reflection, which would lead to a decrease in position sensing accuracy, two protrusions 10 are provided on the inner wall of the outer shell 1. The two protrusions 10 are respectively located on both sides of the limiting groove 14, and the detection port 13 is located on both sides of the recess 9 that cooperate with the protrusions 10. The collection tube 8 and the pressure plate 18 are both made of transparent acrylic.

[0035] In order to keep the sample inside the receiving cavity 83 and prevent the sample from being sucked out of the collection tube 8, a grid 85 is provided on the negative pressure hole.

[0036] In order to both seal the sampling port 86 to prevent the sample from leaking out during biopsy sampling and facilitate the quick removal of the sample during testing, the sampling assembly includes a sampling port 86 set on the sampling wall 82, a sampling plate 87 snapped onto the sampling port 86, and a clamping block 88 provided on the sampling plate 87.

[0037] The position sensing unit includes an infrared sensor; infrared radiation, also known as infrared light, possesses properties such as reflection, refraction, scattering, interference, and absorption. Any substance with a certain temperature (above absolute zero) can radiate infrared radiation. Infrared sensors do not directly contact the object being measured, thus eliminating friction and offering advantages such as high sensitivity and fast response. An infrared sensor comprises an optical system, a detection element, and a conversion circuit. Optical systems can be categorized into transmissive and reflective types based on their structure. The detection element is primarily a thermistor, with thermistors being the most commonly used. When a thermistor is exposed to infrared radiation, its temperature rises, causing a change in resistance (this change may increase or decrease, as thermistors can be classified as positive temperature coefficient thermistors or negative temperature coefficient thermistors). This change is converted into an electrical signal output by the conversion circuit.

[0038] To facilitate the installation and fixation of the positioning sensing unit, slots 15 are provided on both sides of the positioning sensing unit, and spring pieces 16 that engage with the slots 15 are provided on the inner walls of both sides of the limiting groove 14.

[0039] In order to seal the limiting groove 14 and prevent blood and secretions during biopsy sampling from contaminating the positioning sensing unit and affecting the positioning detection accuracy, a pressure plate 18 is provided on the limiting groove 14, and the pressure plate 18 is sealed to the groove wall of the limiting groove 14 by a sealing ring 17.

[0040] During assembly, firstly, the positioning sensing unit is inserted between the two spring pieces 16 in the limiting groove 14. Then, the pressure plate 18 is pressed to seal the positioning sensing unit in the limiting groove 14 and connects it to the biopsy system host through the wiring channel. Next, the collection tube 8 is inserted into the receiving chamber 7 in sequence, so that the detection wall 81 of the collection tube 8 faces the detection port 13. The sealing plate 3 presses the collection tube 8 into the inner cylinder 2. Then, the inner cylinder 2 is inserted into the outer shell 1, so that the limiting ring 5 cooperates with the outer shell 1. Then, the outer shell 1 is installed on the sampling device through the mounting cover 4. The sampling device limits the position of the limiting ring 5 so that the inner cylinder 2 can only rotate. Finally, the rotating shaft 6 fixes and seals the inner cylinder 2 to the biopsy system host.

[0041] During breast biopsy sampling, the sampling device takes a sample, and the biopsy system host draws a vacuum to store the sample in the collection tube 8 through the inlet and negative pressure port. The position sensing unit 12 receives the infrared light emitted by the sample in the collection tube 8 through the pressure plate 18 and the detection wall 81 (because the temperature of the biopsy sample is higher than that of the collection tube 8, the intensity of the emitted infrared light is higher than that of the sample's surrounding environment). This confirms that the collection tube 8 contains a biopsy sample and displays this information on the biopsy system host for easy observation by the operator. At this time, the operator can manually rotate the inner cylinder 2 or the biopsy system host can automatically rotate the inner cylinder 2 so that the recesses 9 on both sides of the detection port 13 corresponding to the next collection tube 8 cooperate with the protrusions 10 on both sides of the position sensing unit to achieve rapid switching and positioning of the collection tube 8. The above operation is repeated to collect and store the next biopsy sample in the second collection tube 8.

[0042] After the sample collection is completed, when it needs to be taken out and refrigerated, simply remove the collection chamber from the biopsy system host and sampling device, take out the inner cylinder 2, remove the sealing plate 3, and take out the collection tube 8 in sequence. When it is necessary to take out the sample in the collection tube 8 for testing, simply use tweezers to clamp the clamping block 88, remove the sampling plate 87 from the sampling port 86, and then take out the sample from the sampling port 86 with tweezers.

[0043] The breast biopsy sampling collection chamber with sample arrival sensing function in this embodiment has a detection port 13 on the inner cylinder 2, which, together with the arrival sensing unit, can quickly sense whether there is a sample in the collection tube 8. This prompts the operator and the biopsy system host to rotate the inner cylinder 2 and switch to the next collection tube 8 for the next sample collection operation, preventing multiple samples from entering the same collection tube 8 or the collection tube 8 from being empty. In addition, a sampling component is set on the collection tube 8, which allows the operator to quickly remove the sample from the sampling port 86 on the sampling wall 82, which is much larger than the inlet hole. This avoids the operator having to pinch the sample out of the narrow through holes at both ends, making the operation convenient and greatly improving the detection efficiency. In addition, a grid 85 is set to block the sample in the receiving cavity 83 to prevent the sample from being sucked out of the collection tube 8.

[0044] Example 2:

[0045] The difference between this embodiment and embodiment 1 is that the position sensing unit 12 includes a detection camera and a light source. The light source illuminates the collection tube 8, and the detection camera captures an image inside the collection tube 8 to identify whether the sample has entered the collection tube 8.

[0046] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Any simple modifications, equivalent changes, and alterations made to the above embodiments based on the technical essence of the present invention shall fall within the scope of the technical solution of the present invention.

Claims

1. A breast biopsy sampling collection container with sample arrival sensing function, connected between a sampling device and a biopsy system host, for storing biopsy samples, characterized in that, include The outer casing is connected to the sampling device. A limiting groove is provided on the inner wall of the outer casing, and a positioning sensing unit is fixed in the limiting groove. Two protrusions are provided on the inner wall of the outer casing, which are respectively located on both sides of the limiting groove. The detection port is located in the recesses that cooperate with the protrusions on both sides. A pressure plate is provided on the limiting groove, and the pressure plate is sealed to the groove wall by a sealing ring. The inner cylinder is embedded in the outer shell. The inner cylinder has accommodating chambers evenly distributed around its circumference. The side of the accommodating chamber that is in contact with the inner wall of the outer shell has a detection port corresponding to the positioning sensing unit. A limiting ring is fixed to the outer periphery of the inner cylinder facing the sampling device. The limiting ring restricts the inner cylinder to the outer shell. A rotating shaft is fixed to the side of the inner cylinder facing the biopsy system host. Several collection tubes, one end of which is fixed to the inner cylinder by a clamping plate and has a negative pressure hole, and the other end is inserted into the receiving chamber and has a sample inlet hole. The collection tube includes a receiving cavity for receiving the sample, a detection wall facing the detection port, and a sampling wall relative to the detection port. The receiving cavity is located between the detection wall and the sampling wall. The sampling wall is provided with a sampling component. The sampling component includes a sampling port provided on the sampling wall. A sampling plate is snapped onto the sampling port. A clamping block is provided on the sampling plate.

2. A breast biopsy sampling collection chamber with sample arrival sensing function according to claim 1, characterized in that, The inner cylinder is provided with a sealing plate on the side facing the biopsy system host, and a pull rod is provided on the sealing plate.

3. A breast biopsy sampling collection chamber with sample arrival sensing function according to claim 1, characterized in that, The outer casing is provided with a mounting cover on the side facing the sampling device, and the outer casing is fixed to the sampling device by the mounting cover.

4. A breast biopsy sampling collection chamber with sample arrival sensing function according to claim 1, characterized in that, The negative pressure hole is equipped with a grid.

5. A breast biopsy sampling collection chamber with sample arrival sensing function according to claim 1, characterized in that, The positioning sensing unit includes an infrared sensor.

6. A breast biopsy sampling collection chamber with sample arrival sensing function according to claim 1, characterized in that, Both sides of the positioning sensing unit are provided with slots, and the inner walls of both sides of the positioning slot are provided with spring pieces that engage with the slots.

7. A breast biopsy sampling collection chamber with sample arrival sensing function according to claim 1, characterized in that, The collecting tube and the pressure plate are both made of transparent acrylic, and the positioning sensing unit, the pressure plate and the detection wall are all arranged in parallel.

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