毛两面针素在制备防治良性前列腺增生药物中的应用
Through in vitro and in vivo experiments, Zanthoxylum bungeanum extract was found to be a drug for the prevention and treatment of benign prostatic hyperplasia, solving the problem of declining efficacy of existing drugs, achieving the effects of inhibiting prostate cell proliferation and reducing prostate index, and broadening the application field of Zanthoxylum bungeanum extract.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- JIANGHAN UNIVERSITY
- Filing Date
- 2023-11-29
- Publication Date
- 2026-07-17
AI Technical Summary
Existing drugs for treating benign prostatic hyperplasia, such as alpha-receptor blockers and 5α-reductase inhibitors, have the problem of decreased efficacy with long-term use, and there are no literature reports on the application of cinnamon bark extract in prostate diseases.
Through in vivo and in vitro experiments, it was found that tufted thorn extract can inhibit benign prostatic hyperplasia (BPH). Drugs containing tufted thorn extract are prepared for the prevention and treatment of BPH, including dosage forms such as tablets, powders, capsules, oral liquids and injections, and can be combined with pharmaceutically acceptable excipients.
Zanthoxylum bungeanum extract significantly inhibits the proliferation of prostatic epithelial and stromal cells and reduces the prostate index, providing a new drug for the prevention and treatment of benign prostatic hyperplasia and broadening the application field of Zanthoxylum bungeanum extract.
Smart Images
Figure CN117442607B_ABST