Oil-controlling and soothing compositions and their applications in cosmetics
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-12-06
- Publication Date
- 2026-08-14
AI Technical Summary
[0003]目前市面上存在大量具有控油舒缓效果的控油产品,但普遍存在控油效果不佳等问题
[0097] To make the objectives, technical solutions, and advantages of this invention clearer and more concise, the invention is described using the following specific embodiments, but the invention is by no means limited to these embodiments. The embodiments described below are merely preferred embodiments of the invention and can be used to describe the invention, but should not be construed as limiting the scope of the invention. It should be noted that any modifications, equivalent substitutions, and improvements made within the spirit and principles of this invention should be included within the protection scope of this invention.
Smart Images

Figure SMS_1 
Figure SMS_2 
Figure SMS_3
Abstract
Description
Technical Field
[0001] This invention relates to the field of daily chemical products, and in particular to an oil-controlling and soothing composition, its application, and cosmetics. Background Technology
[0002] People with oily skin have overactive sebaceous glands, resulting in a greasy face that is difficult to clean and has an unsightly shine. Excessive oil production can also lead to facial skin conditions such as sebaceous plugs, acne, seborrheic dermatitis, enlarged pores, and even seborrheic alopecia.
[0003] Currently, there are many oil-controlling products on the market that claim to have oil-controlling and soothing effects, but they generally suffer from poor oil-controlling performance. Summary of the Invention
[0004] Therefore, it is necessary to provide an oil-controlling and soothing composition that can effectively reduce abnormal sebum secretion, as well as its application and cosmetics.
[0005] In a first aspect, the present invention provides an oil-controlling and soothing composition comprising sodium subtilisin.
[0006] The aforementioned oil-controlling and soothing composition, through the inhibition of 5α-reductase by sodium subtilisin, regulates the original pathway of sebum secretion, rapidly and effectively reducing abnormal sebum secretion, while also soothing the skin. Furthermore, this oil-controlling and soothing composition contains no hormones or drugs, making it safe and non-irritating. When applied to skin care products, especially facial care products, it can reduce sebum secretion, improve skin condition, and reduce inflammation; when applied to shampoo and conditioner products, it can effectively improve seborrheic alopecia.
[0007] In some embodiments, the oil-controlling and soothing composition further includes at least one of cornflower water, sorrel extract, arborvitae leaf extract, and purslane extract.
[0008] In some embodiments, the oil-controlling and soothing composition comprises, by weight, the following components:
[0009] Sodium subtilis lipopeptide, 1 to 25 parts
[0010] Cornflower water, 1 to 20 parts
[0011] 1 to 10 parts of sorrel extract
[0012] 1 to 20 parts of Platycladus orientalis leaf extract, and
[0013] Purslane extract, 1 to 15 parts.
[0014] In some embodiments, the oil-controlling and soothing composition comprises, by weight, the following components:
[0015] 2 to 6 parts of sodium subtilis lipopeptide
[0016] Cornflower water, 4 to 8 parts
[0017] 6 to 10 parts of sorrel extract
[0018] 2 to 8 parts of Platycladus orientalis leaf extract, and
[0019] 2 to 8 parts of purslane extract.
[0020] In some embodiments, the oil-controlling and soothing composition further comprises, by weight, 1 to 10 parts of butanediol; and / or, 0.1 to 1 part of p-hydroxyacetophenone; and / or, 1 to 93 parts of water; and / or, the pH value of the oil-controlling and soothing composition is 6.8 to 7.5.
[0021] In some embodiments, the total mass of the sodium subtilis lipopeptide, the cornflower water, the sorrel extract, the arborvitae leaf extract, and the purslane extract in the oil-controlling and soothing composition is 5% to 97.9%.
[0022] In a second aspect, the present invention provides the application of the above-described oil-controlling and soothing composition in the preparation of cosmetics.
[0023] In a third aspect, the present invention provides a cosmetic product comprising the above-described oil-controlling and soothing composition.
[0024] In some embodiments, the cosmetic product includes at least one of skin care products and shampoo and conditioner products.
[0025] In some embodiments, the skin care product includes at least one of facial care products and hand care products; and / or, the shampoo and conditioner product includes at least one of shampoo, conditioner, and hair mask.
[0026] In some embodiments, the oil-controlling and soothing composition is present in the cosmetic at a mass content of 1% to 10%. Detailed Implementation
[0027] To facilitate understanding of the present invention, a more comprehensive description is provided below, along with preferred embodiments. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. It should be understood that these embodiments are provided to provide a thorough and complete understanding of the disclosure of the present invention.
[0028] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.
[0029] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this invention, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified.
[0030] One of the main reasons for abnormally oily skin is that testosterone in sebaceous gland cells can be converted into more active dihydrotestosterone under the action of 5α-reductase. Excessive testosterone and dihydrotestosterone can lead to increased sebaceous gland volume and increased sebum secretion, resulting in many problems such as sebaceous plugs, acne, seborrheic alopecia, and enlarged pores.
[0031] One embodiment of the present invention provides an oil-controlling and soothing composition comprising sodium subtilisin.
[0032] The aforementioned oil-controlling and soothing composition, through the inhibition of 5α-reductase by sodium subtilisin, regulates the original pathway of sebum secretion, rapidly and effectively reducing abnormal sebum secretion, while also soothing the skin. Furthermore, this oil-controlling and soothing composition contains no hormones or drugs, making it safe and non-irritating. When applied to skin care products, especially facial care products, it can reduce sebum secretion, improve skin condition, and reduce inflammation; when applied to shampoo and conditioner products, it can effectively improve seborrheic alopecia.
[0033] In some embodiments, the above-mentioned oil-controlling and soothing composition may include, in addition to sodium subtilis lipopeptide, at least one of cornflower water, sorrel extract, arborvitae leaf extract and purslane extract.
[0034] In the above-mentioned oil-controlling and soothing composition, sodium subtilis lipopeptide has a strong 5α-reductase inhibitory effect, low irritation, and can promote the penetration of water-soluble active ingredients; cornflower water contains triterpenoids with anti-inflammatory effects, which can treat dermatitis, inhibit induced skin allergies, enhance capillary resistance, and inhibit capillary permeability to have an anti-inflammatory effect; sorrel extract contains anthraquinones, flavonoids, vitamins, tannins, and other components, which have antibacterial, anti-inflammatory, blood-activating, and hemostatic effects, and can play a good role in conditioning the skin; arborvitae leaf extract contains rich volatile oils and flavonoids, which have antibacterial and anti-inflammatory effects, and the volatile oil in arborvitae leaves can also relieve skin itching and pain.
[0035] In some embodiments, the oil-controlling and soothing composition includes sodium subtilis lipopeptide, cornflower water, sorrel extract, arborvitae leaf extract, and purslane extract.
[0036] The aforementioned oil-controlling and soothing composition combines sodium subtilis lipopeptide, cornflower water, sorrel extract, arborvitae leaf extract, and purslane extract to form an oil-controlling and soothing composition. On one hand, it rapidly and effectively reduces abnormal sebum secretion by inhibiting the original pathway of 5α-reductase regulation of sebum secretion. On the other hand, it conditions the skin and repairs the skin barrier. The synergistic effect of the various components effectively reduces abnormal sebum secretion and soothes the skin. Furthermore, this oil-controlling and soothing composition contains no hormones or drugs, making it safe and non-irritating. When applied to skin care products, especially facial care products, it can reduce sebum secretion, improve skin condition, and reduce inflammation. When applied to shampoo and conditioner products, it can effectively improve seborrheic alopecia.
[0037] In some embodiments, the above-described oil-controlling and soothing composition, by weight, comprises the following components:
[0038] Sodium subtilis lipopeptide, 1 to 25 parts
[0039] Cornflower water, 1 to 20 parts
[0040] 1 to 10 parts of sorrel extract
[0041] 1 to 20 parts of Platycladus orientalis leaf extract, and
[0042] Purslane extract, 1 to 15 parts.
[0043] It is understood that the aforementioned "1 to 25 parts of sodium subtilis lipopeptide" refers to the fact that the weight parts of sodium subtilis lipopeptide in the oil-controlling and soothing composition can be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 15, 18, 20, or 25 parts. Further, the weight parts of sodium subtilis lipopeptide in the aforementioned oil-controlling and soothing composition can be within the range formed by any two of the above-mentioned values. Preferably, the weight parts of sodium subtilis lipopeptide are 2 to 6 parts.
[0044] The aforementioned "1 to 20 parts cornflower water" refers to the fact that the weight percentage of cornflower water in the oil-controlling and soothing composition can be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 15, 18, or 20 parts. Further, the weight percentage of cornflower water in the aforementioned oil-controlling and soothing composition can be within the range formed by any two of the above-mentioned values. Preferably, the weight percentage of cornflower water is 4 to 8 parts.
[0045] Furthermore, the cornflower water mentioned above can be commercially available cornflower water.
[0046] The phrase "1 to 10 parts of Sorrel Extract" refers to the fact that the weight percentage of Sorrel Extract in the oil-controlling and soothing composition can be 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10 parts. Further, the weight percentage of Sorrel Extract in the oil-controlling and soothing composition can be within the range defined by any two of the aforementioned values. Preferably, the weight percentage of Sorrel Extract is 6 to 10 parts.
[0047] Furthermore, the aforementioned sorrel extract can be a commercially available sorrel extract.
[0048] The aforementioned "1 to 20 parts of Platycladus orientalis leaf extract" refers to the fact that the weight parts of Platycladus orientalis leaf extract in the oil-controlling and soothing composition can be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 15, 18, or 20 parts. Further, the weight parts of Platycladus orientalis leaf extract in the aforementioned oil-controlling and soothing composition can be within the range formed by any two of the above-mentioned values. Preferably, the weight parts of Platycladus orientalis leaf extract are 2 to 8 parts.
[0049] Furthermore, the above-mentioned Platycladus orientalis leaf extract can be a commercially available Platycladus orientalis leaf extract.
[0050] The aforementioned "1 to 15 parts of purslane extract" refers to the fact that the weight parts of purslane extract in the oil-controlling and soothing composition can be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, or 15 parts. Further, the weight parts of purslane extract in the aforementioned oil-controlling and soothing composition can be within the range formed by any two of the above-mentioned values. Preferably, the weight parts of purslane extract are 2 to 8 parts.
[0051] Furthermore, the aforementioned purslane extract can be a commercially available purslane extract.
[0052] Furthermore, the oil-controlling and soothing composition includes the following components:
[0053] 2 to 6 parts of sodium subtilis lipopeptide
[0054] Cornflower water, 4 to 8 parts
[0055] 6 to 10 parts of sorrel extract
[0056] 2 to 8 parts of Platycladus orientalis leaf extract, and
[0057] 2 to 8 parts of purslane extract.
[0058] Furthermore, the aforementioned purslane extract can be a commercially available purslane extract.
[0059] Furthermore, the oil-controlling and soothing composition includes the following components:
[0060] 4 to 6 parts of sodium subtilis lipopeptide
[0061] Cornflower water, 5 to 8 parts
[0062] 7 to 10 parts of sorrel extract.
[0063] Four to eight parts of Platycladus orientalis leaf extract, and
[0064] Portulaca extract, 4 to 8 parts.
[0065] It is understood that the oil-controlling and soothing composition can be a combination or mixture of the above components, or a mixture of the above components.
[0066] In some embodiments, the oil-controlling and soothing composition further includes 1 to 10 parts by weight of butylene glycol. It is understood that the weight parts of butylene glycol in the oil-controlling and soothing composition can be 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10 parts. Further, the weight parts of butylene glycol in the oil-controlling and soothing composition can be within the range formed by any two of the above values. Preferably, the weight parts of butylene glycol are 3 to 5 parts. Adding butylene glycol to the oil-controlling and soothing composition can further improve its moisturizing and skin-care effects, while also further inhibiting microbial growth.
[0067] In some embodiments, the oil-controlling and soothing composition further includes 0.1 to 1 part by weight of p-hydroxyacetophenone. It is understood that the weight parts of p-hydroxyacetophenone in the oil-controlling and soothing composition can be 0.1, 0.2, 0.3, 0.4, 0.6, 0.8, or 1 part. Further, the weight parts of p-hydroxyacetophenone in the oil-controlling and soothing composition can be within the range formed by any two of the above values. Preferably, the weight parts of p-hydroxyacetophenone are 0.4 to 0.8 parts. Adding p-hydroxyacetophenone can achieve a preservative effect, extending the shelf life of the oil-controlling and soothing composition.
[0068] In some embodiments, the oil-controlling and soothing composition further comprises 1 to 97 parts by weight of water. It is understood that the weight percentage of water in the oil-controlling and soothing composition can be 1, 10, 40, 50, 60, 70, 80, 90, 93, or 97 parts. Further, the weight percentage of water in the oil-controlling and soothing composition can be a range between any two of the above values. Preferably, the weight percentage of water in the oil-controlling and soothing composition is 54.6 to 68.6 parts.
[0069] In some embodiments, the pH value of the oil-controlling and soothing composition is 6.8 to 7.5.
[0070] In some embodiments, the total mass of sodium subtilis lipopeptide, cornflower water, sorrel extract, arborvitae leaf extract and purslane extract in the oil-controlling and soothing composition is 5% to 97.9%.
[0071] Understandably, the effective oil-controlling and soothing ingredients in the oil-controlling and soothing composition include sodium subtilis lipopeptide, cornflower water, sorrel extract, arborvitae leaf extract, and purslane extract.
[0072] In one embodiment of the present invention, a method for preparing the above-mentioned oil-controlling and soothing composition is provided, comprising the following steps:
[0073] The above-mentioned sodium subtilis lipopeptide, cornflower water, sorrel extract, arborvitae leaf extract and purslane extract were mixed to obtain an oil-controlling and soothing composition.
[0074] In some embodiments, the step of mixing the above-mentioned sodium subtilis lipopeptide, cornflower water, sorrel extract, arborvitae leaf extract, and purslane extract includes: first preparing the sorrel extract, arborvitae leaf extract, and purslane extract into aqueous solutions, and then mixing the aqueous solutions of the sorrel extract, arborvitae leaf extract, and purslane extract with the sodium subtilis lipopeptide and cornflower water. Preparing the sorrel extract, arborvitae leaf extract, and purslane extract into aqueous solutions before mixing them with the sodium subtilis lipopeptide and cornflower water facilitates uniform mixing and reduces stirring time.
[0075] In some embodiments, the oil-controlling and soothing composition further includes 0.1 to 1 part of p-hydroxyacetophenone. Further, p-hydroxyacetophenone can be added by directly mixing it with sodium subtilis lipopeptide, cornflower water, sorrel extract, arborvitae leaf extract, and purslane extract, or by forming an aqueous solution with at least one of the sorrel extract, arborvitae leaf extract, and purslane extract, or by using both methods simultaneously.
[0076] In some embodiments, the method for preparing the oil-controlling and soothing composition includes the following steps S10-S20:
[0077] S10. Under heating conditions, p-hydroxyacetophenone is dissolved in water to obtain an aqueous solution of p-hydroxyacetophenone. Further, the heating temperature can be 80℃~90℃.
[0078] S20. Add sodium subtilis lipopeptide, sorrel extract, arborvitae leaf extract and purslane extract to the cooled aqueous solution of p-hydroxyacetophenone, stir until dissolved, then add cornflower water and stir evenly to obtain an oil-controlling and soothing composition.
[0079] In some embodiments, the mass fraction of the sorrel extract in the aqueous solution of the sorrel extract is 10% to 30%. Preparing the sorrel extract into an aqueous solution of a specific concentration before mixing it with other components facilitates uniform mixing and reduces stirring and mixing time.
[0080] In some embodiments, the aqueous solution of the above-mentioned sorrel extract further includes 0.4% to 0.8% by mass of p-hydroxyacetophenone.
[0081] In some embodiments, the mass fraction of the arborvitae leaf extract in the aqueous solution of the above-mentioned arborvitae leaf extract is 10% to 40%. Preparing the arborvitae leaf extract into an aqueous solution of a specific concentration before mixing it with other components is beneficial for uniform mixing and reduces stirring and mixing time.
[0082] In some embodiments, the aqueous solution of the above-mentioned Platycladus orientalis leaf extract further includes 0.4% to 0.8% p-hydroxyacetophenone by mass.
[0083] In some embodiments, the mass fraction of purslane extract in the aqueous solution of the above-mentioned purslane extract is 10% to 40%. Preparing the purslane extract into an aqueous solution of a specific concentration before mixing it with other components is beneficial for uniform mixing and reduces stirring and mixing time.
[0084] In some embodiments, the aqueous solution of the purslane extract further includes 0.4% to 0.8% p-hydroxyacetophenone by mass.
[0085] In some embodiments, the step of mixing the above-mentioned sodium subtilis lipopeptide, cornflower water, sorrel extract, arborvitae leaf extract and purslane extract includes the following steps S31-S32:
[0086] S31. Preparation of aqueous solution of Sorrel extract: Dissolve p-hydroxyacetophenone in water at 80℃~90℃, then cool to room temperature, add Sorrel powder, and stir until the Sorrel powder dissolves to obtain an aqueous solution of Sorrel extract.
[0087] S32. Preparation of aqueous solution of Platycladus orientalis leaf extract: Dissolve p-hydroxyacetophenone in water at 80℃~90℃, then cool to room temperature, add Platycladus orientalis leaf powder, and stir until the Platycladus orientalis leaf powder dissolves to obtain an aqueous solution of Platycladus orientalis leaf extract.
[0088] S33. Preparation of aqueous solution of purslane extract: Dissolve p-hydroxyacetophenone in water at 80℃~90℃, then cool to room temperature, add purslane powder, and stir until the purslane powder dissolves to obtain an aqueous solution of purslane extract.
[0089] S34. Preparation of the oil-controlling and soothing composition:
[0090] A. Weigh the aqueous solutions of Sorrel extract, Platycladus orientalis leaf extract, Portulaca oleracea extract, water and p-hydroxyacetophenone, butylene glycol and cornflower water from the above steps (S31~S33) according to the component formula of the oil-controlling and soothing composition, and set aside.
[0091] B. Heat the weighed water to 80℃~90℃, add p-hydroxyacetophenone and stir until p-hydroxyacetophenone is completely dissolved; after cooling to room temperature, add sodium subtilis lipopeptide and stir for 5 minutes until sodium subtilis lipopeptide is evenly dissolved, then add butylene glycol, cornflower water, sorrel extract aqueous solution, arborvitae leaf extract aqueous solution, and purslane extract aqueous solution in sequence, stir until completely uniform, and adjust the pH to 6.8~7.5 with sodium hydroxide to obtain the oil-controlling and soothing composition.
[0092] It can be understood that the weight parts of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract in the oil-controlling and soothing composition are respectively the weight parts of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract contained in the aqueous solutions of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract added in step B in the oil-controlling and soothing composition. The weight parts of p-hydroxyacetophenone in the oil-controlling and soothing composition refer to the total weight parts of p-hydroxyacetophenone contained in the aqueous solutions of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract added in step B, plus any additional p-hydroxyacetophenone added in step B, in the soothing composition. Similarly, the weight parts of water in the oil-controlling and soothing composition refer to the total weight parts of water contained in the aqueous solutions of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract added in step B, plus any additional water added in step B, in the soothing composition.
[0093] In one embodiment of the present invention, the application of the above-mentioned oil-controlling and soothing composition in the preparation of cosmetics is provided.
[0094] The above-mentioned oil-controlling and soothing composition can effectively reduce abnormal sebum secretion and soothe the skin. Therefore, it can be used in the preparation of cosmetics and can be widely used in skin care products and shampoo and conditioner products, including but not limited to skin care products.
[0095] Skin care products include, but are not limited to, facial care products and hand care products. Facial care products include, but are not limited to, at least one of serums, creams, toners, lotions, masks, and cleansers. Hand care products include, but are not limited to, at least one of hand creams, hand masks, and hand soaps.
[0096] Among them, hair care products include, but are not limited to, at least one of shampoo, conditioner and hair mask.
[0097] To make the objectives, technical solutions, and advantages of this invention clearer and more concise, the invention is described using the following specific embodiments, but the invention is by no means limited to these embodiments. The embodiments described below are merely preferred embodiments of the invention and can be used to describe the invention, but should not be construed as limiting the scope of the invention. It should be noted that any modifications, equivalent substitutions, and improvements made within the spirit and principles of this invention should be included within the protection scope of this invention.
[0098] To better illustrate the present invention, the following embodiments are provided for further explanation. The specific embodiments are as follows.
[0099] The raw materials and product models used in the embodiments and comparative examples of this invention are as follows. Unrestricted raw materials are commercially available common raw materials:
[0100] Sodium subtilis lipopeptide: Sodium subtilis lipopeptide produced by Beijing Yanwei Technology Co., Ltd. through fermentation of THY-7 / Pg3-srfA; Cornflower water: Water-extracted pure dew, content >99%; Sorrel extract: Water-extracted dried pure powder, content >99%; Platycladus orientalis leaf extract: Water-extracted dried pure powder, content >99%; Portulaca oleracea extract: Water-extracted dried pure powder, content >99%.
[0101] Example 1
[0102] The formula of the oil-controlling and soothing composition prepared in this embodiment is: 1 part of sodium subtilis lipopeptide and 99 parts of deionized water.
[0103] The specific preparation process is as follows:
[0104] (1) Weigh each component according to the above formula and set aside.
[0105] (2) Add the weighed sodium subtilis lipopeptide to the weighed deionized water and stir for 15 minutes until it is evenly dissolved. Adjust the pH to 6.8-7.5 with sodium hydroxide to obtain the oil-controlling and soothing composition.
[0106] The preparation methods of Examples 2-3 are basically the same as those of Example 1, except that the formulations of the oil-controlling and soothing compositions are different. The formulations of the oil-controlling and soothing compositions prepared in Examples 1-3 are shown in Table 1.
[0107] Example 4
[0108] The formula of the oil-controlling and soothing composition prepared in this embodiment is as follows: 1 part of sodium subtilis lipopeptide, 1 part of purslane extract, and 98 parts of deionized water.
[0109] The specific preparation process is as follows:
[0110] (1) Weigh each component according to the above formula and set aside.
[0111] (2) Add the weighed sodium subtilis lipopeptide to the weighed deionized water and stir for 15 minutes until it is evenly dissolved. Then add the purslane extract and stir for 10 minutes until it is completely dissolved. Adjust the pH to 6.8-7.5 with sodium hydroxide to obtain the oil-controlling and soothing composition.
[0112] The preparation methods of Examples 5-7 are basically the same as those of Example 4, the only difference being the different formulations of the oil-controlling and soothing compositions. The formulations of the oil-controlling and soothing compositions prepared in Examples 4-7 are shown in Table 1.
[0113] Example 8
[0114] The formula of the oil-controlling and soothing composition prepared in this embodiment is as follows: 5 parts butylene glycol, 3 parts sodium subtilis lipopeptide, 2 parts cornflower water, 2 parts sorrel extract, 3 parts arborvitae leaf extract, 3 parts purslane extract, 0.4 parts p-hydroxyacetophenone, and 81.6 parts deionized water.
[0115] The specific preparation steps are as follows:
[0116] (1) Weigh each component according to the above formula and set aside.
[0117] (2) Take an appropriate amount of deionized water and heat it to 80℃~85℃. Add p-hydroxyacetophenone and stir until it is completely dissolved. After cooling to room temperature, add the weighed sodium subtilis lipopeptide, sorrel extract, arborvitae leaf extract, purslane extract and the remaining deionized water. Stir for 20 minutes until it is evenly dissolved. Then add butylene glycol and cornflower water in sequence and stir for 5 minutes until it is completely even. Adjust the pH to 6.8~7.5 with sodium hydroxide to obtain the oil-controlling and soothing composition.
[0118] The preparation methods of Examples 9-15 are basically the same as those of Example 8, except that the formulations of the oil-controlling and soothing compositions are different. The formulations of the oil-controlling and soothing compositions prepared in Examples 1-15 are shown in Table 1.
[0119] Example 16
[0120] The formula of the oil-controlling and soothing composition prepared in this embodiment is as follows: 4 parts of sodium subtilis lipopeptide, 2 parts of cornflower water, 4 parts of sorrel extract, 6 parts of arborvitae leaf extract, 8 parts of purslane extract, and 76 parts of deionized water.
[0121] The specific preparation steps are as follows:
[0122] (1) Weigh each component according to the above formula and set aside.
[0123] (2) Weigh out the sodium subtilis lipopeptide, sorrel extract, arborvitae leaf extract and purslane extract and add them to deionized water. Stir for 30 minutes until they are evenly dissolved. Then add cornflower water and stir for 5 minutes until they are completely even. Adjust the pH to 6.8-7.5 with sodium hydroxide to obtain the oil-controlling and soothing composition.
[0124] Example 17
[0125] The formulation in this embodiment is the same as that in Example 1, namely, the oil-controlling and soothing composition consists of 5 parts butylene glycol, 3 parts sodium subtilis lipopeptide, 2 parts cornflower water, 2 parts sorrel extract, 3 parts arborvitae leaf extract, 3 parts purslane extract, 0.4 parts p-hydroxyacetophenone, and 81.6 parts deionized water. The only difference is in the preparation steps.
[0126] The specific preparation steps in this embodiment are as follows:
[0127] (1) Preparation of aqueous solution of sorrel extract
[0128] 79.6 parts of deionized water and 0.4 parts of p-hydroxyacetophenone were heated together to dissolve. After the p-hydroxyacetophenone was completely dissolved, the mixture was cooled to room temperature. Then, 20 parts of sorrel powder were weighed and added to the solution, and stirred until completely dissolved to obtain an aqueous solution of sorrel extract with a mass percentage of 20%.
[0129] (2) Preparation of aqueous solution of Platycladus orientalis leaf extract
[0130] 69.6 parts of deionized water and 0.4 parts of p-hydroxyacetophenone were heated together to dissolve. After the p-hydroxyacetophenone was completely dissolved, the mixture was cooled to room temperature. Then, 30 parts of arborvitae leaf powder were weighed and added to the solution. The mixture was stirred until completely dissolved to obtain an aqueous solution of arborvitae leaf extract with a mass percentage of 30%.
[0131] (3) Preparation of aqueous solution of purslane extract
[0132] 59.6 parts of deionized water and 0.4 parts of p-hydroxyacetophenone were heated together to dissolve. After the p-hydroxyacetophenone was completely dissolved, the mixture was cooled to room temperature. Then, 40 parts of purslane powder were weighed and added to the solution, and stirred until completely dissolved to obtain an aqueous solution of purslane extract with a mass percentage of 40%.
[0133] The weight parts involved in steps (1) to (3) when preparing the aqueous solution of the plant extracts are only the parts in the preparation process of the aqueous solution of each plant extract, and are different from the parts of the oil-controlling and soothing composition.
[0134] (4) Preparation of oil-controlling and soothing composition
[0135] A. Weigh appropriate amounts of the aqueous solution of 20% Sorrel extract in step (1), 30% Platycladus orientalis extract in step (2), and 40% Portulaca oleracea extract in step (3) according to the above formula, and add p-hydroxyacetophenone, deionized water, butylene glycol, and cornflower water as needed, for later use.
[0136] B. Heat the weighed deionized water to 80°C, add p-hydroxyacetophenone and stir until completely dissolved; after cooling to room temperature, add sodium subtilis lipopeptide and stir for 8 minutes until it is evenly dissolved. Then, add butylene glycol, cornflower water, 20% Sorrel extract aqueous solution, 30% Platycladus orientalis leaf extract aqueous solution, and 40% Portulaca oleracea extract aqueous solution to the solution and stir for 5 minutes until completely homogeneous. Adjust the pH to 6.8-7.5 with sodium hydroxide to obtain the oil-controlling and soothing composition.
[0137] The weight parts of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract in the oil-controlling and soothing composition are respectively the weight parts of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract contained in the aqueous solutions of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract added in step B in the oil-controlling and soothing composition. The weight parts of p-hydroxyacetophenone in the oil-controlling and soothing composition refer to the total weight parts of p-hydroxyacetophenone contained in the aqueous solutions of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract added in step B, plus any additional p-hydroxyacetophenone added in step B, in the soothing composition. Similarly, the weight parts of water in the oil-controlling and soothing composition refer to the total weight parts of water contained in the aqueous solutions of Rumex acetosa extract, Platycladus orientalis leaf extract, and Portulaca oleracea extract added in step B, plus any additional water added in step B, in the soothing composition.
[0138] The preparation methods of Examples 18-21 are basically the same as those of Example 8, except that the formulation of the prepared oil-controlling and soothing composition is different, as shown in Table 1.
[0139] The preparation method of Comparative Example 1 is basically the same as that of Example 8, except that the formulation of the prepared oil-controlling and soothing composition is different. The specific formulation is shown in Table 1.
[0140] The formulations of each embodiment and comparative example are shown in Table 1.
[0141] Table 1
[0142]
[0143] The following are performance tests.
[0144] 5α-Reductase Inhibition Rate Test
[0145] Reaction Principle: Testosterone is converted to dihydrotestosterone (DHT) under the catalysis of 5α-reductase. Adding a 5α-reductase inhibitor to the reaction system inhibits the catalytic activity of 5α-reductase, thereby suppressing testosterone consumption and reducing DHT production. Testosterone exhibits characteristic absorption at 242 nm. The amount of testosterone participating in the reaction decreases after the addition of the 5α-reductase inhibitor. After the reaction, the absorbance of testosterone at 242 nm increases compared to the blank control group (without the 5α-reductase inhibitor). Monitoring the absorbance at 242 nm using HPLC and calculating the absorbance rate allows for the assessment of whether the substance inhibits 5α-reductase and the magnitude of that inhibition. A higher absorbance value indicates a higher inhibition rate of 5α-reductase.
[0146] The specific testing steps are as follows:
[0147] 1. Preparation of testosterone standard curve: Prepare testosterone standards with concentrations of 50 μmol / L, 100 μmol / L, 200 μmol / L, 500 μmol / L, 750 μmol / L, 1000 μmol / L, and 1500 μmol / L, with an injection volume of 10 μL. Record the chromatograms and calculate the content according to the external standard method.
[0148] 2. Preparation of blank group: Add 50 μL of testosterone T, 25 μL of 5α-reductase, 50 μL of reduced coenzyme II, and 10 μL of water to the reaction tube in sequence, mix well, incubate at 37℃ for 60 min, and then measure the absorbance value A of the mixture at 242 nm to obtain the absorbance value of the blank group (A0).
[0149] 3. Preparation of positive control group: 50 μL of testosterone T, 25 μL of 5α-reductase, 50 μL of reduced coenzyme II, and 10 μL of finasteride were added to the reaction tube in sequence, mixed well, and incubated at 37℃ for 60 min. The absorbance value A of the mixture at 242 nm was then measured to obtain the absorbance value (Af) of the positive group.
[0150] 4. Test group: Add 50 μL of testosterone T, 25 μL of 5α-reductase, 50 μL of reduced coenzyme II, and 10 μL of the oil-controlling and soothing composition prepared in the example or comparative example to the reaction tube in sequence. Mix well and incubate at 37°C for 60 min. Then measure the absorbance value A of the mixture at 242 nm to obtain the absorbance value (An) of the test group.
[0151] 5. Calculation of absorbance (I):
[0152] The absorbance of the positive control group is I = (Af - A0) / A0 × 100%.
[0153] The absorbance of each example group and comparative example is I = (An - A0) / A0 × 100%
[0154] The absorbance test data of the oil-controlling and soothing compositions prepared in the positive control, each example, and the comparative example are shown in Table 2:
[0155] Table 2
[0156]
[0157] As shown in Table 2, the absorbance of Examples 1-21 ranged from 6.12% to 75.14%. Compared to Example 15, Comparative Example 1 did not contain sodium subtilisin. The absorbance of the oil-controlling and soothing composition obtained in Example 15 reached 53.14%, while the absorbance of the oil-controlling and soothing composition prepared in Comparative Example 1 was only 10.36%. Therefore, the addition of sodium subtilisin can improve the oil-controlling effect of the oil-controlling and soothing composition.
[0158] In Examples 18-21, without the addition of cornflower water, sorrel extract, arborvitae leaf extract, and purslane extract, the absorbance of the prepared oil-controlling and soothing compositions was only 12.65%-14.16%; while the absorbance of the oil-controlling and soothing compositions prepared in Examples 8-17 reached 40.86%-75.14%. The absorbance values of Examples 8-17 were significantly higher than those of Examples 18-21, indicating that the oil-controlling and soothing compositions prepared in Examples 8-17 exhibited significantly higher inhibition rates against 5α-reductase compared to those in Examples 18-21, demonstrating a better oil-controlling effect. Furthermore, in Examples 8-17, the absorbance of Example 9 reached 75.14%, very close to that of finasteride. This indicates that the oil-controlling and soothing composition prepared in Example 9 had a better inhibition rate against 5α-reductase.
[0159] (2) Inhibition rate of hyaluronidase
[0160] The inhibitory effect of the oil-controlling and soothing compositions of each embodiment and comparative example on hyaluronidase was tested. Hyaluronidase is a specific cleavage enzyme of hyaluronic acid; inhibiting its activity can ensure the normal content and function of hyaluronic acid. Therefore, the anti-allergic activity of the oil-controlling and soothing compositions can be evaluated using the hyaluronidase inhibition rate as an indicator. The higher the hyaluronidase inhibition rate, the better the soothing effect of the oil-controlling and soothing compositions.
[0161] The specific steps are as follows:
[0162] 1. Take four centrifuge tubes and label them A, B, C and D respectively. Add the oil-controlling and soothing composition to be tested to centrifuge tubes A and B respectively, and add distilled water to centrifuge tubes C and D respectively. Add hyaluronidase solution to centrifuge tubes A and C, and add acetate buffer to centrifuge tubes B and D. Shake to mix well, and place in a constant temperature water bath at 37°C for 20 minutes.
[0163] 2. Add 12.5 mmol / L calcium chloride solution to centrifuge tubes A, B, C, and D in sequence, shake to mix well, and place in a constant temperature water bath at 37°C for 20 minutes.
[0164] 3. Add 250 μL of substrate (sodium hyaluronate) solution to centrifuge tubes A and C respectively, and add acetate buffer to centrifuge tubes B and D respectively. Shake to mix well, place in a constant temperature water bath at 37°C for 40 min, and then remove and let stand at room temperature for 10 min.
[0165] 4. Add distilled water, 0.4 mol / L sodium hydroxide solution, and acetylacetone solution to centrifuge tubes A, B, C, and D in sequence, shake to mix thoroughly, and place each centrifuge tube in a boiling water bath for 15 min, then in an ice bath for 10 min, and then at room temperature for 10 min.
[0166] 5. Add P-DAB solution (prepared by mixing 0.8 g of p-dimethylaminobenzaldehyde, 15 mL of concentrated hydrochloric acid, and 15 mL of anhydrous ethanol) to centrifuge tubes A, B, C, and D respectively, shake to mix thoroughly, and then add 3 mL of anhydrous ethanol. Let stand at room temperature for 30 min, and then measure the absorbance (Am) of the mixture at 530 nm.
[0167] 6. The formula for calculating the hyaluronidase inhibition rate is:
[0168] Hyaluronidase inhibition rate (%) = [(OD C -OD D )-(OD A -OD B )] / (OD C -OD D )×100%
[0169] During the test: OD A -OD value of (hyaluronidase + sample + sodium hyaluronate) sample solution;
[0170] OD B -(acetic acid buffer + sample + acetate buffer) OD value of the blank sample;
[0171] OD C -OD value of (hyaluronidase + deionized water + sodium hyaluronate) control solution;
[0172] OD D - (acetic acid buffer + deionized water + acetate buffer) OD value of the control blank;
[0173] OD value = log10(1 / Am)
[0174] The soothing effects of the oil-controlling and soothing compositions in each embodiment and comparative example are shown in Table 3:
[0175] Table 3
[0176]
[0177] Example 22
[0178] This embodiment provides an oil-controlling serum, the composition of which is as follows:
[0179] Aqueous phase:
[0180] 5 parts glycerin
[0181] 5 parts of butylene glycol
[0182] 0.05 parts of disodium EDTA
[0183] 0.20 parts of p-hydroxyacetophenone
[0184] Sodium polyacrylate grafted starch 0.05 parts
[0185] 74.77 parts deionized water
[0186] Oil phase:
[0187] 3 parts of isononyl isononate
[0188] 0.50 parts of tocopherol acetate
[0189] 1 part diisostearyl malate
[0190] 1 part of polydimethylsiloxane
[0191] Cetearyl alcohol oleate and sorbitan oleate 1.2 parts
[0192] Add phase:
[0193] 0.15 parts of acrylic (ester) / C10-30 alkyl acrylate crosspolymer
[0194] 0.04 parts sodium hydroxide
[0195] Oil-controlling and soothing composition (5 parts)
[0196] Capryloyl hydroxamic acid 0.4 parts
[0197] 0.1 parts of fragrance
[0198] The composition with oil-controlling effect is the oil-controlling and soothing composition prepared in Example 1.
[0199] The preparation method of the oil-control serum includes the following steps:
[0200] 1) Accurately weigh all materials according to the above formula and set aside;
[0201] 2) In the oil phase pretreatment tank, accurately weighed oil phase material is put into the reactor and heated together to 92℃-98℃, while the stirrer is turned on until it is completely melted to obtain an oil phase mixture;
[0202] 3) In the aqueous phase pretreatment tank, accurately weighed aqueous phase material is added into the reactor and heated together to 92℃-98℃, while the stirrer is turned on until it is completely dissolved to obtain an aqueous phase mixture;
[0203] 4) The oil phase mixture filtered through the pipeline is drawn into the emulsification tank that has been preheated to 90°C, and then the water phase mixture is drawn in. The scraper agitator, the rapid agitator and the homogenizer are turned on in sequence. The mixture is kept warm and stirred for 10-15 minutes. Then the cooling device is turned on to start cooling down and the temperature inside the tank is reduced to 80°C.
[0204] 5) When the temperature drops below 80℃, take a sample for pH testing. When the temperature of the paste drops to 55℃-60℃, add fragrance, oil-controlling composition, acrylic (ester) / C10-30 alkanol acrylate crosspolymer, and octanoyl hydroxamic acid. Stir thoroughly and then continue to cool to 35℃-40℃. Add sodium hydroxide to adjust the pH value to obtain the oil-controlling essence.
[0205] The oil-controlling essence obtained in this embodiment is a milky white liquid with a pleasant fragrance. After application to the skin, it leaves the skin feeling refreshed and smooth. Long-term shelf storage tests (3 years at room temperature) and repeated heat resistance (40±1℃, no turbidity after 24 hours of restoring to room temperature) and cold resistance (-15±1℃, normal system without turbidity after 24 hours of restoring to room temperature) destructive tests have shown that all sensory, physicochemical, and hygiene indicators of the product meet the relevant national standards.
[0206] Example 23
[0207] The preparation method of the oil-controlling essence in this embodiment is basically the same as that in Example 22. The only difference is that the composition with oil-controlling effect used in the formula of this embodiment is the oil-controlling and soothing composition prepared in Example 9.
[0208] Example 24
[0209] This embodiment provides an oil-controlling water, the composition of which is shown below:
[0210] 5 parts of butylene glycol
[0211] 3 parts glycerin
[0212] 5 parts propylene glycol
[0213] Witch hazel extract 0.3 parts
[0214] 0.01 parts tea tree oil
[0215] 0.4 parts of p-hydroxyacetophenone
[0216] LRI 0.05 parts
[0217] Oil-controlling and soothing composition (5 parts)
[0218] 0.01 parts of fragrance
[0219] 81.6 parts deionized water
[0220] The composition with oil-controlling effect is the oil-controlling and soothing composition prepared in Example 1.
[0221] The preparation steps are as follows:
[0222] According to the above formula, take an appropriate amount of deionized water and heat it to 80℃~90℃. Add p-hydroxyacetophenone and stir until it is completely dissolved. After cooling to room temperature, add the remaining deionized water, butylene glycol, glycerin, propylene glycol, witch hazel extract, and tea tree oil in sequence and stir until they are mixed evenly. Add the oil-controlling and soothing composition and stir until it is mixed evenly. Then, dissolve the fragrance and solubilizer LRI and add it to the mixture. Stir to mix thoroughly. Finally, adjust the pH to 6.8-7.5 with sodium hydroxide to obtain the oil-controlling water.
[0223] This embodiment yields an oil-controlling water-based product that is a transparent solution with a pleasant fragrance. When applied to the skin, it feels refreshing and has a good skin feel. After long-term storage testing (3 years at room temperature) and repeated heat resistance (placed at 40±1℃ for 24 hours, and remaining clear after returning to room temperature), cold resistance (placed at -15±1℃ for 24 hours, and remaining normal with no turbidity after returning to room temperature), and destructive testing, all sensory, physicochemical, and hygiene indicators of the product meet the relevant national standards.
[0224] Example 25
[0225] The method for preparing the oil-controlling water in this embodiment is basically the same as that in Example 24. The only difference is that the oil-controlling composition used in the formula of this embodiment is the oil-controlling and soothing composition prepared in Example 9.
[0226] Oil control effect evaluation
[0227] Measuring instrument: Sebumeter (skin oil analyzer).
[0228] The skin's sebum secretion is tested using a Sebumeter. Based on the duration of action, the oil-controlling effects of cosmetics can be divided into short-term oil control (4 hours, 8 hours, etc.) and long-term oil control (14 days, 28 days, etc.).
[0229] The oil-control efficacy of cosmetics was tested according to T / ZHCA 002-2018. Forty healthy Chinese male and female subjects, aged 20-55 years (20 men and 20 women), were selected. These subjects had dry, dehydrated skin on both cheeks and excessive oil secretion on the forehead. Before cleansing, the baseline oil secretion on the central forehead of women was >100 μg / cm³, and the baseline oil secretion on the central forehead of men was >120 μg / cm³. For each product example, 5 female and 5 male subjects were selected. Oil secretion on the test sites was recorded before product use, 4 hours after use, and after 28 days of continuous use.
[0230] The specific testing procedure was as follows: Subjects cleansed their skin with a cleansing product and dried it with a tissue. After the skin condition met the testing standards, the test product (Examples 22-25) containing an oil-controlling and soothing composition was applied to the right cheek, while an essence or toner containing an equal amount of placebo (water) was applied to the left cheek. Skin parameters at the test sites were measured 4 hours later to obtain data on sebum secretion before and 4 hours after product use. Subsequently, subjects used the product twice daily, morning and evening, applying the oil-controlling essence or toner sample (Examples 22-25) containing the oil-controlling and soothing composition to the right cheek and an essence or toner containing an equal amount of placebo (water) to the left cheek. After 28 consecutive days of use, subjects cleansed their skin with a cleansing product and dried it with a tissue. After the skin condition met the testing standards, skin parameters at the test sites were measured to obtain sebum secretion after 28 days. The sebum secretion of the left and right cheeks was calculated using a formula. The rate of change in sebum secretion was calculated as follows: Sebum secretion change rate (%) after 4 hours of product use = (T4 - BL) × 100% / BL; Sebum secretion change rate (%) after 28 days of product use = (T28 - BL) × 100% / BL; where BL is the amount of sebum secreted at the test site before product application; T4 is the amount of sebum secreted at the test site 4 hours after product application; and T28 is the amount of sebum secreted at the test site 28 days after product application. The average rate of change was then calculated. The result of this test was P < 0.001.
[0231] The changes in skin sebum secretion after using the products of Examples 22-25 are shown in Table 4 below.
[0232] Table 4
[0233]
[0234] Note: Control groups 1 and 2 represent the change in sebum secretion on the left cheek after applying an equal amount of placebo-added serum. Control groups 3 and 4 represent the change in sebum secretion on the left cheek after applying an equal amount of placebo-added oil-controlling toner.
[0235] Example 26
[0236] This embodiment prepares a shampoo with the following component formula:
[0237] 49.05 parts water
[0238] 5 parts of sodium lauryl ether sulfate (AES)
[0239] 15 parts of sodium methyl cocoyl taurate
[0240] 5 parts of sodium lauroyl sarcosinate
[0241] 8 parts of cocamidopropyl betaine
[0242] 2 parts of sodium cocoyl glutamate
[0243] 3 parts of PEG-150 pentaerythritol tetrastearate
[0244] 0.2 parts amino acids
[0245] 0.3 parts hydrolyzed keratin
[0246] 0.1 part of disodium EDTA
[0247] Polyquaternium-7 1 part
[0248] 0.3 parts sodium chloride
[0249] Oil-controlling and soothing composition (5 parts)
[0250] 0.3 parts DMDM hydantoin
[0251] 0.5 parts flavoring
[0252] 5 parts rosemary hydrosol
[0253] Citric acid 0.25 parts
[0254] The composition with oil-controlling effect is the oil-controlling and soothing composition prepared in Example 1.
[0255] The preparation steps are as follows:
[0256] According to the above formula, take an appropriate amount of deionized water and heat it to 70-80℃. Add disodium EDTA and stir until it is completely dissolved. Then, add sodium lauryl ether sulfate (AES), sodium methyl cocoyl taurate, sodium lauroyl sarcosinate, cocamidopropyl betaine, sodium cocoyl glutamate, and PEG-150 pentaerythritol tetrastearate and stir until completely dissolved. Add amino acids and stir until completely dissolved. Cool down to below 40℃ and add hydrolyzed keratin, polyquaternium-7, sodium chloride, and DMDM hydantoin and stir until completely dissolved. Add fragrance and rosemary hydrosol and stir to mix thoroughly. Finally, adjust the pH to 5.8-6.5 with citric acid to obtain the shampoo.
[0257] Example 27
[0258] The method for preparing the shampoo in this embodiment is basically the same as that in Example 26, except that the oil-controlling composition used in the formula of this embodiment is the oil-controlling and soothing composition prepared in Example 9.
[0259] Performance Testing: Eighty male and eighty female volunteers with oily hair were recruited and divided into four groups of 10 men and 10 women (20 people per group). Group 1 used the shampoo containing the soothing composition of Example 26, while Group 2 used the shampoo containing an equal amount of placebo (water). The oiliness of the hair was tested at 8h, 24h, and 48h after the first wash, and the oil control effect was scored. Then, the volunteers washed their hair every three days, with Group 1 using the shampoo of Example 26 and Group 2 using the shampoo containing an equal amount of placebo (water). After 28 days, the oil control of the hair was tested again. Group 3 used the shampoo containing the soothing composition of Example 27, and Group 4 used the shampoo containing an equal amount of placebo (water). The oiliness of the hair was tested at 8h, 24h, and 48h after the first wash, and the oil control effect was scored. Then, the volunteers washed their hair every 3 days. Group 3 used the shampoo from Example 27, and Group 4 used a shampoo with an equal amount of placebo (water) added. After 28 days, the volunteers were tested on the oil control of their hair after washing. The test scoring indicators are as follows:
[0260] Oil control effectiveness was rated on a scale of 1 to 5, where 1 indicates very oily, 2 indicates moderately oily, 3 indicates average, 4 indicates refreshing, and 5 indicates very refreshing. The results were taken as the average of each group, rounded to one decimal place. Specific rating results are shown in Table 5.
[0261] Table 5
[0262]
[0263] According to the volunteer evaluation scores in Table 5, the shampoo with added oil-controlling and soothing ingredients was more effective than the shampoo with added placebo (water).
[0264] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0265] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the protection scope of the present invention. Therefore, the protection scope of this invention patent should be determined by the appended claims, and the specification can be used to interpret the content of the claims.
Claims
1. An oil-controlling and soothing composition, characterized in that, By weight, the oil-controlling and soothing composition comprises the following components: Sodium subtilis lipopeptide, 1 to 25 parts Cornflower water, 1 to 20 parts 1 to 10 parts of sorrel extract 1 to 20 parts of Platycladus orientalis leaf extract, and Purslane extract 1 to 15 parts; The pH value of the oil-controlling and soothing composition is 6.8 to 7.
5.
2. The oil-controlling and soothing composition as described in claim 1, characterized in that, By weight, the oil-controlling and soothing composition comprises the following components: 2 to 6 parts of sodium subtilis lipopeptide Cornflower water, 4 to 8 parts 6 to 10 parts of sorrel extract 2 to 8 parts of Platycladus orientalis leaf extract, and 2 to 8 parts of purslane extract.
3. The oil-controlling and soothing composition according to any one of claims 1 to 2, characterized in that, By weight, the oil-controlling and soothing composition further includes: 1 to 10 parts of butanediol; and / or, 0.1 to 1 part of p-hydroxyacetophenone; and / or, 1 to 92.9 parts water.
4. The oil-controlling and soothing composition according to any one of claims 1 to 2, characterized in that, The total mass of the sodium subtilis lipopeptide, the cornflower water, the sorrel extract, the arborvitae leaf extract, and the purslane extract in the oil-controlling and soothing composition is 5% to 97.9%.
5. The use of the oil-controlling and soothing composition according to any one of claims 1 to 4 in the preparation of cosmetics.
6. A cosmetic product, characterized in that, The cosmetic product includes the oil-controlling and soothing composition according to any one of claims 1 to 4.
7. The cosmetic product as described in claim 6, characterized in that, The cosmetics include at least one of skin care products and shampoo and conditioner products.
8. The cosmetic product as described in claim 7, characterized in that, The skin care products include at least one of facial care products and hand care products; and / or, the shampoo and conditioner products include at least one of shampoo, conditioner, and hair mask.
9. The cosmetic product according to any one of claims 7 to 8, characterized in that, The oil-controlling and soothing composition is present in the cosmetic at a mass content of 1% to 10%.
Citation Information
Patent Citations
Stable peptide containing active substance obtained through fermentation
CN111773155A