植入式全柔性神经电极及其制备方法

By designing a flexible substrate and neural probe assembly, the problem of poor matching with target tissue during the implantation of multi-channel neural electrodes was solved, achieving efficient neural signal acquisition and improved implantation yield.

CN117582229BActive Publication Date: 2026-07-17INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI
Filing Date
2023-12-27
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing multichannel neural electrodes require implantation tools during the implantation process. The electrode array of flexible electrodes is relatively fixed and cannot be well matched with the target tissue, resulting in a low implantation yield.

Method used

An implantable fully flexible neural electrode was designed, comprising a flexible base layer and multiple neural probe groups. The flexible base layer consists of a first flexible layer and a second flexible layer. The neural probe groups correspond one-to-one with the support layer. Metal wires extend from the inside of the neural probes to the support layer. The flexible base layer can be bent to match the shape of the target tissue, ensuring that the neural probes are completely implanted.

Benefits of technology

This technology maximizes the fit between the flexible substrate and the target tissue while acquiring multiple neural signals in a single session, thereby improving the implantation yield and reducing damage to the target tissue.

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Abstract

本发明提供一种植入式全柔性神经电极及其制备方法,植入式全柔性神经电极包括:柔性基层、多个神经探针组和多根金属导线,柔性基层包括第一柔性层,第一柔性层构造有多个间隔布设的支撑层,相邻两个支撑层通过第二柔性层连接;多个神经探针组与多个支撑层一一对应,神经探针组包括多个间隔布设的神经探针,神经探针的一端连接于支撑层;每根金属导线由神经探针内部延伸至支撑层内部,且由支撑层露出。本发明的植入式全柔性神经电极,柔性基层由第一柔性层和第二柔性层构成,柔性基层的柔性使得其可以弯折成与植入的目标组织的外形轮廓相匹配的形状,以使多个神经探针均能够完全植入目标组织,进而有效提升植入的良率。
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