A composition for removing body stretch marks and its preparation method

CN117582393BActive Publication Date: 2026-09-01PENGS (HUIZHOU) IND DEV CO LTD
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Patent Information

Application Number
CN202311458501.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-11-03
Publication Date
2026-09-01
Estimated Expiration
2043-11-03

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Benefits of technology

[0033]本发明提供了一种祛身体纹路的组合物及其制备方法,所述组合物包含祛纹啫喱、祛纹霜两个产品,组合使用,通过不同功效原料的搭配,协同达到淡化膨胀纹的效果。本发明的产品操作方便,无需额外的工具,成本低;制备方法简单,满足大批量生产制造的需求。

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Abstract

This invention discloses a composition for removing body stretch marks and its preparation method, belonging to the field of skincare technology. The composition comprises two products: a stretch mark removal gel and a stretch mark removal cream, composed of stretch mark removal active ingredients and commonly used cosmetic ingredients. The stretch mark removal effect is achieved by adjusting the proportions of silicone and the active ingredients. Testing revealed that using the stretch mark removal gel and cream together has a synergistic effect, significantly improving the stretch mark removal result. The preparation method provided by this invention is simple, easy to prepare, and meets the needs of mass production.
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Description

Technical Field

[0001] This invention belongs to the field of skin care technology, specifically relating to a composition for removing body wrinkles and its preparation method. Background Technology

[0002] Stretch marks, obesity marks, and growth marks are all types of striae distensae, a special type of skin scar that often develops secondary to pregnancy, rapid development during puberty, rapid weight gain, or the use of glucocorticoids. In the early stages, excessive capillary formation causes striae distensae to appear as red or dark red streaks. Later, pigment loss occurs, eventually forming stable white or silver lines on the skin surface. Stretch marks cause significant stress for those seeking cosmetic improvement, both physically and psychologically; therefore, there is a substantial market demand for treatments to reduce their appearance.

[0003] Traditional treatments for fading stretch marks include phototherapy, such as: 1. Pulsed dye laser, a classic vascular laser treatment that effectively improves red stretch marks; 2. For white stretch marks, where the epidermis is thin and pigment is lost, improvement can be achieved by increasing melanin production, primarily using excimer lasers (308nm). Multiple treatments generally yield good results; 3. Collagen-boosting treatments. Almost all physical energy-based technologies stimulate the proliferation of skin fibroblasts, leading to the synthesis and secretion of new collagen. Fractional laser technology creates multiple three-dimensional columnar micro-thermal damage zones, initiating repair and generating new collagen to reduce stretch marks. While these methods effectively fade stretch marks, they are cumbersome, requiring patients to visit specialized institutions, and are relatively expensive.

[0004] In addition, there are some massage oils on the market that claim to reduce wrinkles, but massage oils feel greasy, are not easily absorbed, and have a poor overall experience and are not effective in reducing wrinkles. Summary of the Invention

[0005] The purpose of this invention is to provide a composition for removing body stretch marks and its preparation method. The composition comprises two products: a stretch mark removal gel and a stretch mark removal cream. When used together, the combination of different active ingredients synergistically achieves the effect of fading stretch marks. The product of this invention is easy to use, requires no additional tools, and is low in cost; the preparation method is simple and meets the needs of mass production.

[0006] To achieve the above objectives, the present invention provides the following technical solution:

[0007] A composition for removing body stretch marks, the composition comprising a stretch mark removal gel and a stretch mark removal cream;

[0008] The wrinkle-removing gel comprises the following components by mass fraction: 8%-16% polydimethylsiloxane; 0-0.1% of a first wrinkle-removing composition, which is ginseng seed extract, rutin, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7; 10-30% of a second wrinkle-removing composition, which is dandelion rhizome / root extract, mallow flower extract, honeysuckle flower extract, wound-healing velvet flower extract, and centella asiatica leaf extract; and cosmetic matrix excipient A: the balance, wherein the cosmetic matrix excipient A is composed of thickener A, moisturizer A, pH adjuster A, preservative A, and water.

[0009] Furthermore, the mass ratio of the golden marrow seed extract, rutin, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7 in the first wrinkle-removing composition is (1-3):(2-5):(1-3):(3-7).

[0010] Furthermore, the mass ratio of dandelion rhizome / root extract, mallow flower extract, honeysuckle flower extract, wound-healing velvet flower extract and centella asiatica leaf extract in the second wrinkle-removing composition is (2-5):(1-3):(3-6):(2-5):(4-7).

[0011] The wrinkle-reducing gel of the present invention contains: (1) Sophora flavescens seed extract and rutin: which can inhibit the production of trypsin, chymotrypsin (mast cell degranulation) and leukocyte elastase, and reduce the formation of stretch marks; (2) Palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, which significantly stimulate the synthesis of macromolecules such as collagen and fibronectin, restore the fiber network of the extracellular matrix, and improve cell activity; (3) Taraxacum mongolicum rhizome / root extract, Mallow flower extract, Lonicera japonica flower extract, Healing velvet flower extract and Centella asiatica leaf extract: which promote the expression of filaggrin, promote the synthesis of natural moisturizing factors, and improve moisturizing and sebum integrity; at the same time, they increase the antagonistic ability of TRPV1 receptor and reduce skin sensitivity; (4) Polydimethylsiloxane: different types of polydimethylsiloxane are used in combination to form a protective film on the skin surface, reduce moisture loss, keep the skin in a moist environment, avoid excessive dryness, and prevent the wrinkles from deepening. In this invention, polydimethylsiloxane is combined with the first and second wrinkle-removing compositions in the formula. When the amount of polydimethylsiloxane added is 8%-16%, the wrinkle-removing effect is relatively ideal. This may be because, under these conditions, the film-forming effect of polydimethylsiloxane on the skin surface can promote the effective action of the active ingredients in the first and second wrinkle-removing compositions on the skin, resulting in better moisturizing and more obvious wrinkle-removing effects. The inventors also unexpectedly discovered that when the mass ratio of golden mung bean seed extract, rutin, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7 is (1-3):(2-5):(1-3):(3-7); and the mass ratio of dandelion rhizome / root extract, mallow flower extract, honeysuckle flower extract, wound-healing velvet flower extract, and centella asiatica leaf extract is (2-5):(1-3):(3-6):(2-5):(4-7), the wrinkle-removing gel is less prone to yellowing and has better stability. It is speculated that under these conditions, the active ingredients in the wrinkle-reducing gel can provide efficacy to the cosmetic, and may interact with each other and with other excipients in the system, affecting the stability of the cosmetic.

[0012] The wrinkle-removing cream comprises the following components by mass fraction: 0.04%-0.06% bisabolol; 2%-10% emulsifier, wherein the emulsifier is selected from one or more of glyceryl stearate, PEG-100 stearate, tocopherol, and vitamin E; 0.5%-4% of a third wrinkle-removing composition, wherein the third wrinkle-removing composition is chamomile extract, violet extract, peony root extract, dendrobium officinale extract, and aloe vera extract; 0.1%-3% of a fourth wrinkle-removing composition, wherein the fourth wrinkle-removing composition is saffron flower extract, galangal leaf extract, lactobacillus fermentation lysate, mannan, and soluble collagen; and cosmetic matrix excipients: balance, wherein the cosmetic matrix excipient B is composed of thickener B, moisturizer B, pH adjuster B, preservative B, skin conditioning agent B, and water.

[0013] Furthermore, the emulsifier is a compound of glyceryl stearate, PEG-100 stearate and vitamin E in a mass ratio of (2-5):(1-3):(0.5-1).

[0014] The wrinkle-removing cream of the present invention contains: (1) Mannan, derived from *Gnaphalium affine*, a plant that grows in arid South African valleys and is commonly used to treat wounds and burns. Mannan can promote the synthesis of fibroblasts and stimulate the production of type I and type III collagen, thereby increasing the overall density of the dermis and making the skin firmer. It can also inhibit the synthesis of leukotrienes and prevent the uncontrolled production of collagen. (2) Bisabolol: soothing and anti-inflammatory, inhibiting 5-lipoxygenase activity and reducing cyclooxygenase gene expression, which can prevent and treat skin erythema; studies have shown that bisabolol can accelerate the healing time of sunburn, mild burns and skin irritation. The wrinkle-removing cream of the present invention uses an emulsifier to encapsulate the oil-soluble components such as bisabolol, water-soluble mannan, dendrobium extract and other components in micelles, which are uniformly dispersed in water to form a relatively stable system with good stability at room temperature. However, during the research and development process, it was found that the wrinkle-removing cream is prone to thickening, sedimentation, layering and yellowing at high temperatures. The inventors unexpectedly discovered that by adding an emulsifier of glyceryl stearate, PEG-100 stearate and vitamin E in a mass ratio of (2-5):(1-3):(0.5-1), the high-temperature stability of the stretch mark cream could be improved.

[0015] Furthermore, the mass ratio of chamomile extract, violet extract, peony root extract, dendrobium officinale extract and aloe vera extract in the third wrinkle-removing composition is (1-4):(1-3):(2-6):(3-5):(4-6).

[0016] Furthermore, the fourth wrinkle-removing composition comprises saffron flower extract, galangal leaf extract, lactobacillus fermentation lysate, and soluble collagen in a mass ratio of (2-4):(2-5):(1-4):(3-6).

[0017] To further enhance the wrinkle-removing effect, this invention also tested the wrinkle-removing gel and cream, finding that the combined effect of the two was far better than using the wrinkle-removing cream or gel alone. In particular, when the mass ratio of the third wrinkle-removing composition (chamomile extract, violet extract, peony root extract, dendrobium officinale extract, and aloe vera extract) was (1-4):(1-3):(2-6):(3-5):(4-6), and the mass ratio of the fourth wrinkle-removing composition (saffron flower extract, ginger leaf extract, lactobacillus fermentation lysate, and soluble collagen) was (2-4):(2-5):(1-4):(3-6), the wrinkle-fading effect was even better. The speculation is that the layering of the anti-wrinkle cream, which contains emulsifiers, reduces surface tension and improves the spreadability of the gel during application. This enhances the absorption of active ingredients in the anti-wrinkle gel, and works synergistically with soluble collagen and bisabolol to restart the energy metabolism of aging cells, promote fibroblast proliferation and extracellular matrix synthesis, thereby deeply promoting skin barrier repair and improving the depth of wrinkles. Simultaneously, the extracts in both formulas—chamomile extract, dandelion rhizome / root extract, violet extract, peony root extract, mallow flower extract, honeysuckle flower extract, aloe vera leaf juice, and dendrobium officinale extract—work synergistically to promote filaggrin expression, promote the synthesis of natural moisturizing factors, and improve moisturizing and sebum integrity; they also increase the antagonistic ability against TRPV1 receptors, reducing skin sensitivity. The inventors also unexpectedly discovered that layering the two products can also improve skin radiance.

[0018] Further, the thickener A is carbomer; the humectant A is selected from one or more of glycerin, 1,2-hexanediol, butylene glycol, 1,2-pentanediol, 1,3-propanediol, nicotinamide, and allantoin; the preservative A is p-hydroxyacetophenone; and the pH adjuster A is aminomethylpropanol.

[0019] Further, the pH adjuster B is citric acid; the moisturizer B is selected from one or more of mineral oil, cetyl alcohol, glycerin, trehalose, allantoin, butylene glycol, 1,2-hexanediol, 1,3-propanediol, and 1,2-pentanediol; the thickener B is sodium polyacrylate; the skin conditioning agent B is ascorbate tetraisopalmitate, Dendrobium officinale extract, and C13-16 isoparaffin; and the preservative B is p-hydroxyacetophenone.

[0020] A second aspect of the present invention provides a method for preparing the aforementioned composition, the method comprising preparing an anti-wrinkle gel and an anti-wrinkle cream, wherein:

[0021] The preparation steps of the wrinkle-removing gel are as follows:

[0022] (1) Pump water into the main pot, add thickener A, stir and heat to 85-88℃, keep warm for 10 minutes;

[0023] (2) Cool down to 60-65℃, add polydimethylsiloxane, stir evenly, and turn on the homogenizer until the material is uniform and free of particles.

[0024] (3) Add the pre-prepared first wrinkle removal composition, second wrinkle removal composition and water, stir evenly and continue to cool;

[0025] (4) Cool down to 50-55℃, add the remaining cosmetic base excipient A in sequence, and stir evenly;

[0026] The preparation steps of the wrinkle-removing cream are as follows:

[0027] (1) Weigh the moisturizer B raw material, heat it to 78-82℃ to dissolve it evenly, add bisabolol, and stir evenly;

[0028] (2) Add water, humectant B, and emulsifier to the main pot, heat to 85-88℃, and stir until well mixed;

[0029] (3) Cool down to 40-45℃, add the third wrinkle removal composition, the fourth wrinkle removal composition and the remaining cosmetic matrix excipient B, and homogenize.

[0030] The third aspect of the present invention also provides a method of using the composition as follows: first, take an appropriate amount of wrinkle-reducing gel and apply it to the skin with wrinkles, spreading it evenly until it is basically absorbed; then take an appropriate amount of wrinkle-reducing cream and gently massage it until absorbed.

[0031] The wrinkle-reducing cream of this invention can promote the absorption of the wrinkle-reducing gel, further achieving the wrinkle-reducing effect. The first step is to apply the wrinkle-reducing gel to the wrinkles and spread it evenly until mostly absorbed, replenishing skin moisture. The second step is to apply the wrinkle-reducing cream on top of the wrinkles and massage until absorbed. This double application works synergistically to fade wrinkles and lock in moisture.

[0032] Compared with the prior art, the advantages and beneficial effects of the present invention are as follows:

[0033] This invention provides a composition for removing body stretch marks and its preparation method. The composition comprises two products: a stretch mark removal gel and a stretch mark removal cream. When used together, the combination of different active ingredients synergistically achieves the effect of fading stretch marks. The product of this invention is easy to use, requires no additional tools, and is low in cost; the preparation method is simple and meets the needs of mass production. Attached Figure Description

[0034] Figure 1 This is a flowchart illustrating the preparation process of the wrinkle-removing gel of the present invention;

[0035] Figure 2 This is a flowchart illustrating the preparation process of the mosquito repellent cream of the present invention.

[0036] Figure 3These are before-and-after photos showing the effects of wrinkle removal. Detailed Implementation

[0037] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0038] Unless otherwise specified, all raw materials used in this invention are commercially available.

[0039] Example 1

[0040] This embodiment provides a composition for removing body stretch marks, the composition comprising a stretch mark removal gel and a stretch mark removal cream;

[0041] The stretch mark removal gel comprises the following components by weight fraction:

[0042] Phase A1 is carbomer: 0.7%;

[0043] Phase B is polydimethylsiloxane: 6%;

[0044] Phase C 25% contains: water, glycerin, nicotinamide, 1,2-hexanediol, butylene glycol, p-hydroxyacetophenone, 1,2-pentanediol, allantoin, asiaticoside, 1,3-propanediol, centella asiatica leaf extract, glycyrrhizin, collagen, carbomer, matricaria flower extract, dandelion rhizome / root extract, peony root extract, violet extract, asiaticoside, velvetleaf flower extract, mallow flower extract, honeysuckle flower extract, dandelion extract. The ingredients include peony root extract, saffron extract, sodium mannose phosphate, pepper leaf / root / stem extract, centella asiatica flower / leaf / stem extract, aloe vera leaf juice, mannose, galangal leaf extract, acetyl hexapeptide-8, nonapeptide-1, and tripeptide-1; wherein the mass ratio of dandelion root / stem / root extract, mallow flower extract, honeysuckle flower extract, velvetleaf flower extract, and centella asiatica leaf extract is 4:2:5:3:6; the remaining components are added in appropriate amounts.

[0045] Phase D consists of: 2% glycerol, 0.5% 1,2-hexanediol, and 0.3% p-hydroxyacetophenone;

[0046] Phase E consists of 4% water and 2% nicotinamide; Mixture A is 0.1%, which contains butylene glycol, water, cetyl hydroxyethyl cellulose, rutin, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, and golden pea seed extract; wherein the mass ratio of golden pea seed extract, rutin, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7 is 2:3:1:5, and the remaining ingredients are added in appropriate amounts.

[0047] Phase F consists of 1% water and 0.1% aminomethylpropanol;

[0048] The balance is phase A.

[0049] The stretch mark cream comprises the following components by weight:

[0050] Phase A: 3% mineral oil, 2% cetyl alcohol, 0.7% emulsifier, wherein the emulsifier is a mixture of glyceryl stearate, PEG-100 stearate and vitamin E in a mass ratio of 3:2:0.7;

[0051] Phase A1: Bisabolol 0.04%, Ascorbate Tetraisopalmitate 0.1%;

[0052] Phase B: Water 3%, Glycerin 4%, Trehalose 0.07%, Allantoin 0.09%;

[0053] Phase C: Sodium polyacrylate 0.5%, polydimethylsiloxane 0.4%, sodium polyacrylate 0.2%;

[0054] Phase D: Butanediol 0.6%, p-hydroxyacetophenone 0.8%, 1,2-hexanediol 0.8%;

[0055] Phase E 4%: Centella asiatica flower / leaf / stem extract, glycerin, 1,2-hexanediol, 1,2-pentanediol, p-hydroxyacetophenone, glycerin, matricaria flower extract, dandelion rhizome / root extract, violet extract, peony root extract, mallow flower extract, honeysuckle flower extract, aloe vera leaf juice, dendrobium officinale extract, aloe vera extract, citric acid, butylene glycol, Centella asiatica flower / leaf / stem extract, velvetleaf flower extract, dandelion extract, peony root extract, saffron flower extract, p-hydroxyacetophenone, dendrobium officinale extract. The ingredients include Aloe vera extract, Alpinia galanga leaf extract, citric acid, mannitol, Lactobacillus fermentation lysate, trehalose, capryloyl hydroxamic acid, soluble collagen, fibronectin, hydroxypropyl tetrahydropyranotriol, mannan, and citric acid. The mass ratio of Matricaria champaca flower extract, Viola yedoensis extract, Paeonia lactiflora root extract, Dendrobium officinale extract, and Aloe vera extract is 3:2:4:2:5. The mass ratio of Saffron flower extract, Alpinia galanga leaf extract, Lactobacillus fermentation lysate, and soluble collagen is 3:3:2:4. Other components are added in appropriate amounts.

[0056] Phase F: The remainder is water.

[0057] This embodiment provides a method for preparing a composition for removing body stretch marks, the method comprising preparing a stretch mark removal gel and a stretch mark removal cream; wherein,

[0058] The preparation steps of the wrinkle-removing gel are as follows:

[0059] (1) Draw phase A into the main pot, add phase A1, stir and heat to 86°C, and keep warm for 10 minutes;

[0060] (2) Cool down to 62°C, add phase B, stir evenly, and turn on the homogenizer until the material is uniform and free of particles.

[0061] (3) Add the pre-prepared E phase, stir well and continue cooling;

[0062] (4) Cool down to 54℃, add phase C, pre-made phase D and phase F in sequence, and stir until homogeneous;

[0063] The preparation steps of the wrinkle-removing cream are as follows:

[0064] (1) Weigh the A phase raw material separately, heat it to 80℃ and dissolve it evenly, add the A1 phase and stir evenly; weigh the C phase separately and stir evenly; heat the D phase separately and dissolve it evenly; weigh the F phase separately and heat and stir it evenly.

[0065] (2) Add phase B to the main pot, heat to 86°C, and stir well;

[0066] (3) Add phase B and homogenize.

[0067] (4) Add phase C and homogenize.

[0068] (5) Cool down to 47℃, add phase D, and stir until homogeneous;

[0069] (6) Cool down to 42℃, add E and F, and homogenize.

[0070] This embodiment also provides a method for using the composition as follows: first, apply an appropriate amount of wrinkle-reducing gel to the skin with wrinkles, spread it evenly until it is basically absorbed, and then apply an appropriate amount of wrinkle-reducing cream and gently massage it until absorbed.

[0071] Example 2

[0072] The difference between this embodiment and Embodiment 1 is that phase B in the wrinkle-removing gel is polydimethylsiloxane: 10%.

[0073] Example 3

[0074] The difference between this embodiment and Embodiment 1 is that phase B in the wrinkle-removing gel is polydimethylsiloxane: 13%.

[0075] Comparative Example 1

[0076] The difference between this comparative example and Example 1 is that polydimethylsiloxane was not added to the wrinkle-removing gel.

[0077] Comparative Example 2

[0078] The difference between this comparative example and Example 1 is that the mass ratio of golden mung bean seed extract, rutin, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7 in the first wrinkle-removing composition is 1:1:3:1.

[0079] In the second wrinkle-removing composition, the mass ratio of dandelion rhizome / root extract, mallow flower extract, honeysuckle flower extract, wound-healing velvet flower extract, and centella asiatica leaf extract is 1:2:2:1:2.

[0080] Comparative Example 3

[0081] The difference between this comparative example and Example 1 is that the emulsifier is a compound of glyceryl stearate, hexadecyl alcohol, and vitamin E in a mass ratio of 1:1:1.

[0082] Comparative Example 4

[0083] The difference between this comparative example and Example 1 is that the mass ratio of chamomile extract, violet extract, peony root extract, dendrobium officinale extract and aloe vera extract in the third wrinkle-removing composition is 1:4:1:1:2.

[0084] The fourth wrinkle-removing composition comprises saffron flower extract, ginger leaf extract, lactobacillus fermentation lysate, and soluble collagen in a mass ratio of 1:1:1:2.

[0085] Comparative Example 5

[0086] The difference between this comparative example and Example 1 is that the first wrinkle-removing composition is palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 in a mass ratio of 1:1; the second wrinkle-removing composition is dandelion rhizome / root extract, honeysuckle flower extract and wound-healing velvet flower extract in a mass ratio of 1:1:1:.

[0087] Comparative Example 6

[0088] The difference between this comparative example and Example 1 is that the third wrinkle-removing composition consists of chamomile extract, violet extract, and peony root extract in a mass ratio of 2:3:2; and the fourth wrinkle-removing composition consists of galangal leaf extract, lactobacillus fermentation lysate, and mannan in a mass ratio of 1:3:3.

[0089] Performance testing

[0090] 1. The moisturizing data of different proportions of polydimethylsiloxane in the stretch mark removal gel were determined. The results are shown in Table 1. The test method was as follows: the right side of the abdomen of each subject was divided into four adjacent areas, and the products of Examples 1-3 and Comparative Example 1 were applied to each area respectively, with the same amount applied.

[0091] Table 1. Moisturizing data for different proportions of polydimethylsiloxane

[0092]

[0093]

[0094] As shown in Table 1, after using the test product for 30 minutes, 1 hour, 1.5 hours, and 2 hours, the skin's stratum corneum moisture content was significantly different from the pre-use value (P<0.05). Better moisturizing effect leads to a more noticeable reduction in wrinkles. Considering the overall skin feel and stability of the formula, 12% was chosen as the final blending ratio.

[0095] 2. Stimulation test

[0096] (1) Patch test

[0097] 1. Test substance: Product of Example 2

[0098] 2. Control: Blank filter paper control

[0099] 3. Participants: A total of 32 female participants, aged 23 to 39 years, with a mean age of 28.91 ± 4.81 years, who met the voluntary inclusion criteria.

[0100] 4. Test method: Using qualified patch testing equipment, the test substance (approximately 0.02 mL-0.025 mL) was placed in the patch testing device using the closed patch test method. The device was then applied to the flexor side of the subject's forearm with hypoallergenic adhesive tape. The test substance was removed after 24 hours. Skin reactions were observed at 0.5, 24, and 48 hours after removal. The results were recorded according to the skin reaction grading standards in the "Cosmetic Safety Technical Specifications" (2015 edition), as shown in Table 2.

[0101] Table 2 Summary of Cosmetic Skin Patch Test Results

[0102]

[0103] Table 2 shows that, in the blank control group (32 participants), one patient experienced a Grade 1 adverse reaction within 0.5 hours; in the stretch mark removal gel group (32 participants), one patient experienced a Grade 1 adverse reaction within 0.5 hours; and in the stretch mark removal cream group (1 patient), one patient experienced a Grade 1 adverse reaction within 0.5 hours. All were within acceptable limits.

[0104] 3. Comparison of the wrinkle-removing effects of the product in Example 2

[0105] Combination use: After cleansing, first apply an appropriate amount of gel to the areas with stretch marks and massage until mostly absorbed; then apply an appropriate amount of the stretch mark cream and massage until absorbed. Use twice daily, morning and evening. See results below. Figure 3 .

[0106] Figure 3In the comparison, A is a user with stretch marks for 5 months, and the area of ​​red scars has been significantly reduced; B is a user with stretch marks for 18 years, and the stretch marks have been filled in, making the skin smoother; C is a user with obesity-related stretch marks for 10 years, and the stretch marks have been significantly reduced, making the skin smoother.

[0107] Of the participants tested, 26 showed significant improvement, 4 showed improvement, and 2 showed slight improvement, resulting in an effectiveness rate of 93.75%.

[0108] 4. Stability Test

[0109] The stretch mark removal gels and creams of Examples 1-3 and Comparative Examples 1-6 were placed at 45°C for 60 days, and the changes were observed on the 30th and 60th days. The test results are shown in Table 3.

[0110] Table 3 Stability Test Results

[0111]

[0112] As shown in Table 3, the embodiments of the present invention exhibit better stability. No yellowing was observed in the 30-day and 60-day heat resistance tests, thus maintaining the best anti-aging activity. The comparative products all showed varying degrees of yellowing.

[0113] The above description represents the preferred embodiments of the present invention. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A composition for removing body stretch marks, characterized in that, The composition comprises a stretch mark removal gel and a stretch mark removal cream; The wrinkle-removing gel comprises the following components by mass fraction: 8%-16% polydimethylsiloxane; 0.1% of a first wrinkle-removing composition, which is composed of *Gynostemma pentaphyllum* seed extract, rutin, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7 in a mass ratio of (1-3):(2-5):(1-3):(3-7); 10-30% of a second wrinkle-removing composition, which is composed of *Taraxacum officinale* rhizome / root extract, *Mallow* flower extract, *Lonicera japonica* flower extract, *Velvetia blakeana* flower extract, and *Centella asiatica* leaf extract in a mass ratio of (2-5):(1-3):(3-6):(2-5):(4-7); and the remainder being cosmetic matrix excipient A, which is composed of thickener A, moisturizer A, pH adjuster A, preservative A, and water. The wrinkle-removing cream comprises the following components by mass fraction: 0.04%-0.06% bisabolol; 2%-10% emulsifier, wherein the emulsifier is a compound of glyceryl stearate, PEG-100 stearate, and vitamin E in a mass ratio of (2-5):(1-3):(0.5-1); and 0.5%-4% of a third wrinkle-removing composition, wherein the third wrinkle-removing composition is a compound of chamomile extract, violet extract, and peony in a mass ratio of (1-4):(1-3):(2-6):(3-5):(4-6). Root extract, Dendrobium officinale extract and Aloe vera extract; 0.1-3% of the fourth wrinkle-removing composition, wherein the fourth wrinkle-removing composition is saffron flower extract, Alpinia galanga leaf extract, Lactobacillus fermentation lysate, mannan and soluble collagen in a mass ratio of (2-4):(2-5):(1-4):(1-3):(3-6); cosmetic matrix excipients: balance, wherein the cosmetic matrix excipient B is composed of thickener B, moisturizer B, pH adjuster B, preservative B, skin conditioning agent B and water.

2. The composition according to claim 1, characterized in that, The thickener A is carbomer; the humectant A is selected from one or more of glycerin, 1,2-hexanediol, butylene glycol, 1,2-pentanediol, 1,3-propanediol, nicotinamide, and allantoin; the preservative A is p-hydroxyacetophenone; and the pH adjuster A is aminomethylpropanol.

3. The composition according to claim 1, characterized in that, The pH adjuster B is citric acid; the moisturizer B is selected from one or more of mineral oil, cetyl alcohol, glycerin, trehalose, allantoin, butylene glycol, 1,2-hexanediol, 1,3-propanediol, and 1,2-pentanediol; the thickener B is sodium polyacrylate; the skin conditioning agent B is ascorbate tetraisopalmitate, Dendrobium officinale extract, and C13-16 isoparaffin; and the preservative B is p-hydroxyacetophenone.

4. A method for preparing the composition according to any one of claims 1-3, characterized in that, The preparation method of the composition includes the preparation of a stretch mark removal gel and a stretch mark removal cream, wherein: The preparation steps of the wrinkle-removing gel are as follows: (1) Pump water into the main pot, add thickener A, stir and heat to 85-88℃, keep warm for 10 minutes; (2) Cool down to 60-65℃, add polydimethylsiloxane, stir evenly, and turn on the homogenizer until the material is uniform and free of particles; (3) Add the pre-prepared first wrinkle removal composition, second wrinkle removal composition and water, stir evenly and continue to cool; (4) Cool down to 50-55℃, add the remaining cosmetic base excipient A in sequence, and stir evenly; The preparation steps of the wrinkle-removing cream are as follows: (1) Weigh the moisturizer B raw material, heat it to 78-82℃ to dissolve it evenly, add bisabolol, and stir evenly; (2) Add water, humectant B, and emulsifier to the main pot, heat to 85-88℃, and stir until homogeneous; (3) Cool down to 40-45℃, add the third wrinkle removal composition, the fourth wrinkle removal composition and the remaining cosmetic matrix excipient B, and homogenize.

Citation Information

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