Analyser and detection system
Patent Information
- Application Number
- CN202311646688.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Priority Date
- 2020-04-30
- Filing Date
- 2020-11-12
- Publication Date
- 2026-08-28
- Estimated Expiration
- 2040-11-12
AI Technical Summary
[0065]本公开至少一实施例提供的一种分析仪以及检测系统,由于分析仪的检测模块包括至少一个检测单元,分析仪在检测过程中可以检测出放置于分析仪的芯片放置结构上的检测芯片中待检测液体的多种物质的含量。
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Figure CN117629920B_ABST
Abstract
Description
[0001] This application is a divisional application of the invention patent application filed on November 12, 2020, with application number 202080002730.9 and title "Analyzer and Detection System". Technical Field
[0002] At least one embodiment of this disclosure relates to an analyzer and a detection system. Background Technology
[0003] In recent years, with the improvement of living standards, the requirements for a balanced diet have become increasingly higher, especially for infants whose main source of nutrition is breast milk, where nutritional balance is particularly important. Testing the content of trace elements in breast milk, such as calcium, zinc, iron, lactose, and protein, can provide mothers with appropriate nutritional guidance based on the test results. Summary of the Invention
[0004] The disclosed embodiments provide an analyzer and a detection system. This analyzer can detect the content of multiple substances in a liquid to be tested within a detection chip during the detection process.
[0005] At least one embodiment of this disclosure provides an analyzer, including: a chip placement structure and at least one detection unit. The chip placement structure is used to place a detection chip, wherein the detection chip has at least one detection area. The at least one detection unit is configured to detect one or more detection areas of the detection chip when the detection chip is placed on the chip placement structure.
[0006] For example, in an analyzer provided in one embodiment of this disclosure, the at least one detection unit includes at least one photoelectric detection unit.
[0007] For example, in an analyzer provided in one embodiment of this disclosure, each of the at least one photoelectric detection unit includes at least one light-emitting element and at least one photoelectric sensing device.
[0008] For example, an analyzer provided in one embodiment of this disclosure further includes an optical path assembly disposed between the chip placement structure and the detection unit, and configured to transmit light emitted from the at least one light-emitting element to the chip placement structure, and to transmit light reflected from the detection chip placed on the chip placement structure to the at least one photoelectric sensing device.
[0009] For example, in an analyzer provided in an embodiment of this disclosure, the optical path assembly includes a split optical disc, which includes at least one set of light-transmitting holes, each corresponding to the at least one photoelectric detection unit. Each set of light-transmitting holes includes at least one light-emitting hole and at least one light-reflecting hole. The at least one light-emitting hole allows light emitted from at least one light-emitting element of the corresponding photoelectric detection unit to pass through, and the at least one light-reflecting hole allows light reflected from the detection chip placed on the chip placement structure to pass through and be transmitted to at least one photoelectric sensing device of the corresponding photoelectric detection unit.
[0010] For example, in an analyzer provided in one embodiment of this disclosure, at least one of the at least one set of light-transmitting holes is a rectangular hole or a circular hole.
[0011] For example, in an analyzer provided in one embodiment of this disclosure, the at least one light emitting aperture is a rectangular aperture, and the at least one light reflecting aperture is a circular aperture.
[0012] For example, in an analyzer provided in one embodiment of this disclosure, at least one of the at least one set of light-transmitting holes has a sidewall that is at least partially inclined relative to the axial direction of the optical disc.
[0013] For example, in an analyzer provided in one embodiment of this disclosure, at least one sidewall of the rectangular hole is inclined relative to the axial direction of the optical disc.
[0014] For example, in an analyzer provided in one embodiment of this disclosure, at least one sidewall of the at least one light-emitting through-hole extending radially along the optical disc is a slope.
[0015] For example, in an analyzer provided in one embodiment of this disclosure, the two sidewalls of the at least one light-emitting through-hole extending radially along the optical disc are inclined relative to the axial direction of the optical disc, and the inclination directions of the two sidewalls are different.
[0016] For example, in an analyzer provided in one embodiment of this disclosure, the angle between the inclined plane containing at least one sidewall of the at least one light-emitting through hole and the axial direction perpendicular to the optical disc ranges from 130 degrees to 140 degrees.
[0017] For example, in an analyzer provided in one embodiment of this disclosure, the opening of the at least one light-emitting aperture on the side away from the at least one photoelectric detection unit is larger than the opening of the at least one light-emitting aperture on the side closer to the at least one photoelectric detection unit.
[0018] For example, in an analyzer provided in one embodiment of this disclosure, at least one sidewall of the at least one light-reflecting through-hole is inclined relative to the axial direction of the optical disc.
[0019] For example, in an analyzer provided in one embodiment of this disclosure, the angle between the inclined plane containing at least one sidewall of the at least one light-reflecting through-hole and the axial direction perpendicular to the optical disc ranges from 115 degrees to 125 degrees.
[0020] For example, in an analyzer provided in one embodiment of this disclosure, the optical disc is configured to be centrally symmetrical, and each of the at least one set of light-transmitting holes is also configured to be centrally symmetrical.
[0021] For example, in an analyzer provided in one embodiment of this disclosure, the optical disc is circular in shape, the at least one set of light-transmitting holes includes multiple sets of light-transmitting holes, and the multiple sets of light-transmitting holes are evenly distributed in a circle around the center of the optical disc.
[0022] For example, in an analyzer provided in one embodiment of this disclosure, each of the at least one set of light-transmitting holes includes two light-emitting holes and one light-reflecting hole, and the two light-emitting holes are disposed on opposite sides of the one light-reflecting hole.
[0023] For example, in an analyzer provided in one embodiment of this disclosure, the two light emitting apertures are symmetrically arranged on opposite sides of the one light reflecting aperture.
[0024] For example, in an analyzer provided in one embodiment of this disclosure, the straight-line distance between the centers of two adjacent light-emitting apertures ranges from 5 mm to 8 mm, and the straight-line distance between the center of one of the two light-emitting apertures in each of the at least one set of light-transmitting apertures and the center of the light-reflecting aperture ranges from 2.5 mm to 4 mm.
[0025] For example, in an analyzer provided in one embodiment of this disclosure, the straight-line distance between the centers of two adjacent light-emitting apertures ranges from 5 mm to 8 mm, and the straight-line distance between the center of the light-emitting aperture and the center of the nearest adjacent light-reflecting aperture in each of the at least one set of light-transmitting apertures ranges from 2.5 mm to 4 mm.
[0026] For example, in an analyzer provided in one embodiment of this disclosure, the optical disc further includes a limiting structure disposed at the edge of the optical disc and extending into the chip placement structure.
[0027] For example, in an analyzer provided in an embodiment of this disclosure, each of the at least one set of light-transmitting holes includes a first sub-reflective through-hole located on the side of the optical disc away from the at least one detection unit and a second sub-reflective through-hole located on the side of the optical disc closer to the at least one detection unit.
[0028] For example, in an analyzer provided in one embodiment of this disclosure, the diameter of the first sub-reflective aperture is smaller than the diameter of the second sub-reflective aperture.
[0029] For example, in an analyzer provided in an embodiment of this disclosure, the surface of the optical disc on the side away from the at least one detection unit includes at least one protrusion. The at least one protrusion protrudes obliquely from the side of the two light emitting apertures of each of the at least one set of light-transmitting apertures that are close to the light reflecting aperture towards the side away from the at least one detection unit. The light reflecting apertures of the at least one set of light-transmitting apertures are located in the at least one protrusion in a one-to-one correspondence, so as to block the light emitted from at least one light-emitting element of the corresponding photoelectric detection unit through the light emitting aperture.
[0030] For example, in an analyzer provided in one embodiment of this disclosure, each of the at least one boss is annular, and each of the at least one boss surrounds the light-reflecting through-hole of each of the at least one set of light-transmitting holes.
[0031] For example, in an analyzer provided in one embodiment of this disclosure, the slope angle of the boss relative to the axial vertical direction of the optical disc ranges from 130 degrees to 140 degrees, and the height of the boss protruding from the light-reflecting through-hole ranges from 0.4 mm to 0.6 mm.
[0032] For example, in an analyzer provided in an embodiment of this disclosure, each of the at least one photoelectric detection unit includes two light-emitting elements and a photoelectric sensor, and the two light-emitting elements are disposed on opposite sides of the photoelectric sensor; the two light-emitting apertures respectively allow light emitted by the two light-emitting elements to pass through, and the one light-reflecting aperture allows light reflected from the detection chip placed on the chip placement structure to pass through and be transmitted to the photoelectric sensor.
[0033] For example, in an analyzer provided in one embodiment of this disclosure, the straight-line distance between the centers of two adjacent light-emitting elements ranges from 5 mm to 8 mm, and the straight-line distance between the center of one of the two light-emitting elements in the same photoelectric detection unit and the center of the photoelectric sensing device ranges from 2.5 mm to 4 mm.
[0034] For example, in an analyzer provided in one embodiment of this disclosure, the straight-line distance between the centers of two adjacent light-emitting elements ranges from 5 mm to 8 mm, and the straight-line distance between the center of the light-emitting element and the center of the nearest adjacent photoelectric sensor in each of the at least one photoelectric detection unit ranges from 2.5 mm to 4 mm.
[0035] For example, in an analyzer provided in one embodiment of this disclosure, the at least one photoelectric detection unit includes a plurality of photoelectric detection units, which are arranged in a row.
[0036] For example, an analyzer provided in one embodiment of this disclosure further includes a separating component disposed between the optical path component and the chip placement structure, wherein the separating component includes a light-transmitting portion configured to allow light emitted from the at least one light-emitting element and light reflected from the detection chip placed on the chip placement structure to pass through.
[0037] For example, in an analyzer provided in one embodiment of this disclosure, the light-transmitting portion of the separating component includes at least one transparent window, corresponding to the at least one photoelectric detection unit, to allow light emitted from at least one light-emitting element of the corresponding photoelectric detection unit and light reflected from the detection chip placed on the chip placement structure to at least one photoelectric sensing device of the corresponding photoelectric detection unit to pass through.
[0038] For example, in an analyzer provided in one embodiment of this disclosure, the separation component further includes a substrate and at least one transparent sheet, the substrate including at least one mounting through-hole, and the at least one transparent sheet being embedded in the at least one mounting through-hole to provide the at least one transparent window.
[0039] For example, an analyzer provided in one embodiment of this disclosure further includes a detection circuit board, the photoelectric detection unit is disposed on the detection circuit board, the detection circuit board includes a first positioning hole, the separating component includes a positioning post and the split optical disc includes a second positioning hole, or the separating component includes a second positioning hole and the split optical disc includes a positioning post, the positioning post being disposed in the first positioning hole and the second positioning hole to connect the split optical disc, the separating component and the detection circuit board.
[0040] For example, an analyzer provided in one embodiment of this disclosure further includes a rotation drive device, wherein the at least one detection unit includes a detection unit, and the rotation drive device is configured to drive the detection unit to rotate relative to the chip placement structure.
[0041] For example, in an analyzer provided in one embodiment of this disclosure, the detection chip further has a calibration reaction area. When the detection chip is placed on the chip placement structure, before detecting the detection area of the detection chip, one of the at least one detection unit is further configured to calibrate the calibration reaction area of the detection chip.
[0042] For example, an analyzer provided in one embodiment of this disclosure further includes a first housing and a second housing, wherein the at least one detection unit is disposed within the space enclosed by the first housing and the second housing.
[0043] For example, in an analyzer provided in one embodiment of this disclosure, the first housing further includes at least one support portion disposed at the bottom of the first housing to provide stable support for the first housing.
[0044] For example, in an analyzer provided in one embodiment of this disclosure, the second housing is hinged to the first housing on a first side, the second housing is configured to be closed to the first housing on a second side, and to be opened to expose the chip placement structure, the first side and the second side being disposed opposite to each other.
[0045] For example, in an analyzer provided in one embodiment of this disclosure, the first housing includes a first sub-opening / closing assembly disposed on the second side, and the second housing includes a second sub-opening / closing assembly disposed on the second side, wherein the first opening / closing assembly and the second sub-opening / closing assembly are configured to be able to engage and disengage from each other, so that the first housing and the second housing are respectively closed and opened to each other.
[0046] For example, in an analyzer provided in one embodiment of this disclosure, the second sub-opening and closing assembly includes a first locking tongue in the shape of an elongated strip and a second locking tongue in the shape of an elongated strip. The first locking tongue and the second locking tongue are arranged side by side in pairs. The first sub-opening and closing assembly includes a groove and a latching member. The latching member is located in the groove. The first end of the first locking tongue and the first end of the second locking tongue are configured to extend into the groove and latch onto the latching member to close the first housing and the second housing, and to disengage from the latching member to open the first housing and the second housing.
[0047] For example, in an analyzer provided in one embodiment of this disclosure, the second sub-opening and closing assembly further includes an elastic element disposed at the middle of the first latch and the middle of the second latch to elastically connect the first latch and the second latch, and configured to apply an elastic force to tend to put the first latch and the second latch in a state that can be snapped onto the snap-fit member.
[0048] For example, in an analyzer provided in one embodiment of this disclosure, the elastic element is a torsion spring, which is used to apply an elastic force that brings the first end of the first latch and the first end of the second latch closer to each other. The second sub-opening assembly also includes a switch connected to the first latch and the second latch and configured to be operable such that the first end of the first latch and the first end of the second latch are separated from the latching member while in a state of being snapped onto the latching member.
[0049] For example, in an analyzer provided in one embodiment of this disclosure, the second sub-opening and closing assembly further includes a connector disposed in the middle of the first latch, and the surface of the connector opposite to the second latch is an inclined surface to form a limiting trajectory, the limiting trajectory being configured to limit the opening and closing angles of the first latch and the second latch.
[0050] For example, an analyzer provided in one embodiment of this disclosure further includes a display device disposed on the second housing.
[0051] For example, an analyzer provided in one embodiment of this disclosure further includes at least one micro switch, which is signal-connected to a display device and configured to control the content displayed on the display device.
[0052] For example, in an analyzer provided in one embodiment of this disclosure, the at least one micro switch includes two micro switches, one of which is disposed at the first end of the first latch and configured to control the switch of the analyzer, and the other of which is disposed at the first end of the second latch and configured to control the display of the analyzer's detection results on the display device.
[0053] For example, an analyzer provided in one embodiment of this disclosure further includes a control device, which is signal-connected to the detection unit and the display device, and is configured to receive the detection result of the detection unit and send the detection result to the display device, wherein the display device is configured to display the detection result.
[0054] For example, an analyzer provided in one embodiment of this disclosure further includes a signal transmitting and receiving device, which is connected to the control device and configured to upload the detection results to a mobile device, or to receive a control signal from the mobile device and transmit the control signal to the control device to control the operation of the analyzer.
[0055] For example, an analyzer provided in one embodiment of this disclosure further includes a temperature sensor and a humidity sensor, which are respectively connected to the control device. The temperature sensor is configured to detect the ambient temperature and upload the temperature detection data to the control device, and the humidity sensor is configured to detect the ambient humidity and upload the humidity detection data to the control device.
[0056] At least one embodiment of this disclosure also provides a detection system, including: an analyzer as described in any of the preceding claims and a detection chip. The detection chip is configured to be placed on the chip placement structure of the analyzer.
[0057] At least one embodiment of this disclosure also provides an analyzer, including a detection module and a control module. The detection module includes a chip placement structure, wherein the detection module is configured to detect at least one detection area of the detection chip when the detection chip having at least one detection area is placed on the chip placement structure; the control module is configured to control the detection operation of the detection module and receive the detection results of the detection module.
[0058] For example, in an analyzer provided in one embodiment of this disclosure, the detection module includes at least one photoelectric detection unit.
[0059] For example, in an analyzer provided in one embodiment of this disclosure, each of the at least one photoelectric detection unit includes at least one light-emitting element and at least one photoelectric sensing device.
[0060] For example, an analyzer provided in one embodiment of this disclosure further includes a beam splitting component disposed between the chip placement structure and the at least one photoelectric detection unit, and configured to transmit light emitted from the at least one light-emitting element to the chip placement structure, and to transmit light reflected from the detection chip placed on the chip placement structure to the at least one photoelectric sensing device.
[0061] For example, an analyzer provided in one embodiment of this disclosure further includes a separating component disposed between the beam splitter and the chip placement structure, wherein the separating component includes a light-transmitting portion configured to allow light emitted from the at least one light-emitting element and light reflected from the detection chip placed on the chip placement structure to pass through.
[0062] For example, an analyzer provided in one embodiment of this disclosure further includes a display module, which is signal-connected to the control module and configured to receive the detection results of the detection module sent by the control module and to display the detection results.
[0063] For example, an analyzer provided in one embodiment of this disclosure further includes a switch module, which is signal-connected to the display module and configured to control the content displayed on the display module.
[0064] For example, an analyzer provided in one embodiment of this disclosure further includes a signal transmitting and receiving device, which is connected to the control module and configured to upload the detection results of the detection module to a mobile device, or to receive a control signal from the mobile device and transmit the control signal to the control module to control the operation of the analyzer.
[0065] This disclosure provides an analyzer and a detection system according to at least one embodiment. Since the detection module of the analyzer includes at least one detection unit, the analyzer can detect the content of multiple substances in the liquid to be detected in the detection chip placed on the chip placement structure of the analyzer during the detection process. Attached Figure Description
[0066] To more clearly illustrate the technical solutions of the embodiments of this disclosure, the accompanying drawings of the embodiments will be briefly described below. Obviously, the drawings described below only relate to some embodiments of this disclosure and are not intended to limit this disclosure.
[0067] Figure 1A A schematic diagram of an analyzer provided according to an embodiment of this disclosure;
[0068] Figure 1B A schematic diagram of an analyzer provided for another embodiment of this disclosure;
[0069] Figure 2 A schematic diagram of the lower structure of an analyzer provided in an embodiment of this disclosure;
[0070] Figure 3 A partial structural diagram of the lower part of an analyzer provided in an embodiment of this disclosure;
[0071] Figure 4A A schematic diagram of the detection module and optical path components of an analyzer provided in an embodiment of this disclosure;
[0072] Figure 4B A cross-sectional schematic diagram of a transparent window of a partition component provided in an embodiment of this disclosure;
[0073] Figure 5A A schematic diagram illustrating the detection principle of an analyzer provided in an embodiment of this disclosure;
[0074] Figure 5B A schematic diagram of the standard curve of absorbance value versus substance content of an analyzer provided in an embodiment of this disclosure;
[0075] Figure 6A This is a schematic diagram of the structure of the optical disc of the analyzer provided in an embodiment of the present disclosure;
[0076] Figure 6B The light-transmitting aperture of the optical disc provided in one embodiment of this disclosure is along Figure 6A A schematic diagram of the cross section EF in the diagram;
[0077] Figure 6C The light-transmitting aperture of the optical disc provided in another embodiment of this disclosure is along Figure 6A A schematic diagram of the cross section EF in the diagram;
[0078] Figure 7 A schematic diagram of the second housing of an analyzer provided in an embodiment of this disclosure;
[0079] Figure 8 This is a schematic diagram of the structure of the second housing of an analyzer provided in an embodiment of the present disclosure;
[0080] Figure 9 A schematic diagram of a second sub-opening / closing component of an analyzer provided in an embodiment of this disclosure;
[0081] Figure 10 A partial structural schematic diagram of the second sub-opening / closing assembly of an analyzer provided in an embodiment of this disclosure;
[0082] Figure 11 This is a partial structural schematic diagram of an analyzer provided in another embodiment of the present disclosure;
[0083] Figure 12A This is a schematic diagram of a detection chip provided in one embodiment of the present disclosure;
[0084] Figure 12B This is a partial structural schematic diagram of a detection chip provided in an embodiment of the present disclosure;
[0085] Figure 12C An exploded view of a detection chip provided in another embodiment of this disclosure;
[0086] Figure 13 A schematic diagram of the detection process of an analyzer provided in an embodiment of this disclosure;
[0087] Figure 14 A schematic diagram of an analyzer provided for yet another embodiment of this disclosure; and
[0088] Figure 15 This is a schematic diagram illustrating an analysis provided for yet another embodiment of the present disclosure. Detailed Implementation
[0089] To make the objectives, technical solutions, and advantages of the embodiments of this disclosure clearer, the technical solutions of the embodiments of this disclosure will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this disclosure. All other embodiments obtained by those skilled in the art based on the described embodiments of this disclosure without creative effort are within the scope of protection of this disclosure.
[0090] Unless otherwise defined, the technical or scientific terms used in this disclosure shall have the ordinary meaning understood by one of ordinary skill in the art to which this disclosure pertains. The terms “first,” “second,” and similar terms used in this disclosure do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Similarly, the terms “an,” “a,” or “the,” and similar terms do not indicate a quantity limitation, but rather indicate the presence of at least one. Terms such as “comprising” or “including” mean that the element or object preceding the term encompasses the elements or objects listed following the term and their equivalents. For ease of description, in some of the accompanying drawings, terms such as “upper,” “lower,” etc., are used only to indicate relative positional relationships; these relative positional relationships may also change accordingly when the absolute position of the described object changes.
[0091] Currently available analytical devices for detecting the substance content of various liquids, such as breast milk and cow's milk, are mainly large-scale testing equipment. These devices are expensive, complex to operate, and require specialized training for operators. Such equipment is primarily concentrated in hospitals or testing institutions, providing substance content testing services to those who need it. Therefore, some liquid testing requires going to a hospital or specialized testing institution, a time-consuming and labor-intensive process that limits the frequency of testing for those who require it. For liquids like breast milk and cow's milk that require frequent testing, regular monitoring of their substance content is particularly important. Therefore, the inventors recognized the significant importance of providing a portable, compact, easy-to-operate, and home-use analyzer for detecting the substance content of liquids such as breast milk.
[0092] Lab-on-a-chip (Lab-on-a-chip) technology integrates or substantially integrates basic operational units such as sample preparation, biological and chemical reactions, and separation and detection onto a single chip, typically a few square centimeters in size, to perform various biological or chemical reactions and analyze their products. The signals generated within the chip need to be detected; currently, the most commonly used detection methods include laser-induced fluorescence, mass spectrometry, ultraviolet light, and chemiluminescence.
[0093] Embodiments of this disclosure provide an analyzer and a detection system. The analyzer includes a first housing, a chip placement structure, and at least one detection unit. The chip placement structure is disposed in the first housing for placing a detection chip, the detection chip having at least one detection area. At least one detection unit is disposed in the first housing and configured to detect one or more detection areas of the detection chip when the detection chip is placed on the chip placement structure.
[0094] Since the analyzer's detection module includes at least one detection unit, the analyzer can detect multiple detection areas of the detection chip during the detection process through at least one detection unit, thereby detecting the content of multiple substances in the liquid to be tested in the detection chip.
[0095] The analyzer and detection system provided in one or more embodiments of the present disclosure will now be described in detail with reference to the accompanying drawings.
[0096] For example, in some examples, Figure 1A This is a schematic diagram of an analyzer provided according to an embodiment of the present disclosure. Figure 1A As shown, the analyzer 1100 includes a first housing 1110, a second housing 1160, and a chip placement structure 1120.
[0097] The chip placement structure 1120 is located within the first housing 1110 and is used to place the detection chip 1200. The first housing 1110 and the second housing 1160 can be opened and closed on one side to facilitate the user's placement and retrieval of the detection chip 1200, and to prevent interference from external light on the detection chip during the operation of the analyzer 1100. The analyzer 1100 also includes a detection unit located below the chip placement structure 1120 within the first housing 1110, for detecting the substance content of the liquid to be tested in the detection chip 1200 placed on the chip placement structure 1120. During use, after preparing the detection chip 1200 containing the sample, the user first opens the first housing 1110 and the second housing 1160, places the detection chip 1200 on the chip placement structure 1120, and then closes the first housing 1110 and the second housing 1160. The analyzer 1100 can detect the substance content of the liquid to be tested in the detection chip 1200. After the detection is completed, the detection result is output. Finally, the user can open the first housing 1110 and the second housing 1160 again to take out the detection chip 1200.
[0098] For example, in some examples, the chip placement structure 1120 is located on the upper surface of the first housing 1110 (e.g., by...). Figure 2 The opening (e.g., formed on the surface of the first shielding plate 1301) in the middle Figure 2 The circular opening 1301a of the first shielding plate 1301 forms a recessed accommodating space within the first housing 1110. For example, the cross-section of this accommodating space is approximately circular. It should be noted that other shapes are also possible, such as rectangular, elliptical, etc. For example, as... Figure 2 As shown, the chip placement structure 1120 consists of an opening 1301a of the first shielding plate 1301, the inner sidewall of the optical disc 1141, and ( Figure 6A (As shown) Separator component 1150 ( Figure 4AThe space formed by the upper surface of the first shielding plate 1301, the split disc 1141, and the partition assembly 1150 will be described in detail later.
[0099] For example, in other embodiments, the second housing 1160 of the analyzer 1100 can be removed. For instance, the upper surface of the first housing 1110 can be made into a light-shielding plane, and an opening is made on the side of the first housing 1110, communicating with the chip placement structure 1120. A stage can be added to the chip placement structure 1120, which can pop out from the opening to place the detection chip 1200 on the stage. The stage is then pushed into the chip placement structure 1120 to detect the chip 1200. It should be noted that the stage can be operated in a drawer-type manner to shield ambient light during the detection of the chip 1200. The embodiments described herein are not limited to the shape and structure of the second housing 1160.
[0100] For example, in other embodiments, the chip placement structure 1120 can also be configured as multiple intersecting beams erected on the opening 1301a of the first shielding plate 1301. The detection chip 1200 can be directly placed on the beams. Furthermore, the beams can be made of a transparent material, or the position of the beams can be offset from the detection area of the detection chip 1200. As another example, multiple support points can be provided on the sidewall of the chip placement structure 1120. The detection chip 1200 has multiple notches on its lower surface corresponding to the positions of these support points. When the detection chip 1200 is placed on the chip placement structure 1120, the multiple support points cooperate with the notches of the detection chip 1200 to stably place the detection chip 1200. As yet another example, a clamping mechanism can be provided on the sidewall of the chip placement structure 1120, and the detection chip 1200 is stably placed in the chip placement structure 1120 through the clamping mechanism. As yet another example, the chip placement structure 1120 can also be configured as a liftable platform to place the detection chip 1200 on the platform for detection. The platform's supporting portion can be a transparent structure, or a light-transmitting structure (e.g., a through-hole) can be formed in the detection area of the corresponding detection chip 1200. It should be noted that the detection chip 1200 in this disclosure refers to a chip that integrates or substantially integrates basic operational units such as sample preparation, biological and chemical reactions, and separation detection onto a single chip, for example, a few square centimeters. For example, the detection chip 1200 can be a microfluidic chip used to detect the substance content of the liquid to be tested.
[0101] For example, in some examples, Figure 1B This is a schematic diagram of an analyzer provided for another embodiment of this disclosure. (See diagram below.) Figure 1BAs shown, the first housing 1110 includes a first support portion 1111 and a second support portion 1112. For example, the first support portion 1111 and the second support portion 1112 are symmetrically arranged with respect to the centerline of the first housing 1110. The first support portion 1111 and the second support portion 1112 are disposed at the bottom of the first housing 1110, for example, each including a support surface. This provides stable support for the first housing 1110 on the plane when the analyzer is placed on the support surface, preventing the first housing 1110 from tilting and causing a shift in the relative positional relationship between the internal structures of the analyzer 1100.
[0102] Figure 2 This is a schematic diagram of the lower structure of an analyzer provided in the above embodiments of the present disclosure; Figure 3 This is a partial structural diagram of the lower part of the analyzer provided in the above embodiments of this disclosure; Figure 4A This is a schematic diagram of the detection unit and optical path components of the analyzer provided in the above embodiments of this disclosure.
[0103] like Figure 2 , Figure 3 as well as Figure 4A As shown, the lower part of the analyzer 1100 includes a first housing 1110 and a chip placement structure 1120. The detection chip 1200 includes multiple detection areas; the detailed structure of the detection chip 1200 can be found in the following description. Figure 12A , Figure 12B as well as Figure 12C In the example shown in the figure, the chip placement structure 1120 provides a cavity for accommodating and supporting the detection chip 1200 and having a cross-sectional shape substantially the same as that of the detection chip 1200, such as the circular cavity shown in the figure. The chip placement structure 1120 may also include a snap-fit structure to fix the placed detection chip, for example, the snap-fit structure includes a limiting block, etc. The embodiments of this disclosure do not limit this.
[0104] The lower part of the analyzer 1100 also includes a detection unit for detecting the placed detection chip 1200. The detection unit can be of various types, for example, including but not limited to photoelectric detection units. The detection unit is disposed in the first housing 1110. In the following description, a photoelectric detection unit is used as an example. Figure 4AAs shown, the detection unit includes at least one photoelectric detection unit. The photoelectric detection unit can be of various types, for example, including but not limited to a single photoelectric detection unit 1131. These photoelectric detection units 1131 are configured to detect multiple detection areas of the detection chip 1200 when the detection chip 1200 is placed on the chip placement structure 1120. Specific examples are described below. For example, a notch can be provided circumferentially on the detection chip 1200, the shape of which is the same as the shape of the limiting block of the chip placement structure 1120. When the detection chip 1200 is placed on the chip placement structure 1120, the notch of the detection chip 1200 is fitted onto the limiting block, so that the detection area of the detection chip 1200 and the photoelectric detection unit 1131 are aligned in a direction perpendicular to the photoelectric detection unit 1131, making it easier and more accurate for the user to place the detection chip 1200 on the chip placement structure 1120. Other alignment methods can also be used in the embodiments of this disclosure, such as setting positioning marks or positioning spring sheets on the chip placement structure 1120 to align with the detection chip 1200. The embodiments of this disclosure are not limited to this.
[0105] In some embodiments, the outer surface of the first housing 1110 is approximately hemispherical. The chip placement structure 1120 is located in the first housing 1110 near its upper side to facilitate the placement of the detection chip. The chip placement structure 1120 includes a first shielding plate 1301, which is connected to the upper side of the first housing 1110, for example, by snap-fit or screw connection. An opening 1301a is provided at the center of the first shielding plate 1301 to form a space for placing the detection chip 1200 in the first housing 1110, providing a receiving chamber. The first shielding plate 1301 can block other stray light outside the first housing 1110, avoiding interference from other light on the detection results. The receiving chamber of the chip placement structure 1120 is, for example, cylindrical to match the shape of the detection chip 1200. The chip placement structure can also be quadrilateral, polygonal, or other shapes, and the embodiments disclosed herein are not limited thereto.
[0106] For example, in other examples, the first housing 1110 may also be of other shapes, such as a cuboid, etc., and the embodiments disclosed herein are not limited thereto.
[0107] like Figure 4AAs shown, the lower part of the analyzer 1100 also includes a detection circuit board 1302, which is disposed below the chip placement structure 1120 in the first housing 1110. A detection unit is disposed on the detection circuit board 1302, corresponding to the detection chip 1200 in the axial direction of the first housing 1110. The detection unit includes multiple photoelectric detection units 1131, which respectively correspond to multiple detection areas of the detection chip in the axial direction of the first housing 1110.
[0108] For example, Figure 4A As shown, multiple photoelectric detection units 1131 are uniformly arranged on the same circumference to detect multiple detection areas of the detection chip 1200, such as simultaneously detecting multiple detection areas of the detection chip 1200, or detecting multiple detection areas of the detection chip 1200 in a certain order, thereby detecting the content of multiple substances in the liquid to be detected in the detection chip 1200. The structural design of multiple photoelectric detection units 1131 uniformly arranged on the same circumference can avoid crosstalk of light in different photoelectric detection units and achieve the accuracy of optical detection.
[0109] It should be noted that the multiple detection areas of the detection chip 1200 are arranged on the same circumference, and the corresponding multiple photoelectric detection units 1131 are evenly arranged on the same circumference. When the multiple detection areas of the detection chip 1200 are arranged on the same circumference, when the detection chip 1200 injects samples from the center, the injection distance of the multiple detection areas is the same, so uniform injection can be achieved.
[0110] For example, in other embodiments, the multiple photoelectric detection units 1131 can be evenly arranged on the vertices of a regular polygon, so that the sample introduction distance of the multiple detection areas of the corresponding detection chip is the same. Of course, without considering the sample introduction distance of the detection areas of the detection chip, the multiple photoelectric detection units 1131 can also be arranged in various shapes, such as arranged in a row, arranged in a matrix, etc. The embodiments of this disclosure are not limited to the arrangement of the multiple photoelectric detection units 1131.
[0111] For example, in some examples, each photodetector unit 1131 includes at least one light-emitting element and at least one photosensitive device. Figure 4AIn the example shown, the photoelectric detection unit 1131 includes two light-emitting elements 1132 and a photoelectric sensor 1133. The two light-emitting elements 1132 (e.g., symmetrically arranged) are located on either side of the photoelectric sensor 1133. For example, the distance between two adjacent light-emitting elements 1132 in different photoelectric detection units 1131 is greater than the distance between the light-emitting element 1132 and the photoelectric sensor 1133 in the same photoelectric detection unit 1131, thereby avoiding interference of optical signals between different photoelectric detection units 1131. The arrangement of the two light-emitting elements 1132 and the photoelectric sensor 1133 ensures that the light emitted by the light-emitting elements 1132 is uniformly incident on the detection area of the detection chip 1200, and also increases the intensity of the incident light provided by the two light-emitting elements 1132 and the intensity of the reflected light after reflection by the detection chip 1200, thereby improving the stability of the analyzer's detection.
[0112] For example, the distance between two adjacent light-emitting elements 1132 located in different photoelectric detection units 1131, such as the straight-line distance between the centers of two adjacent light-emitting elements 1132, ranges from 5 mm to 8 mm. As another example, in... Figure 4A In this system, the straight-line distance between the centers of two adjacent light-emitting elements 1132 is approximately 6 mm. For example, in the same photoelectric detection unit 1131, the straight-line distance between the center of one of the two light-emitting elements 1132 and the center of the photoelectric sensing device 1133 ranges from 2.5 to 4 mm. As another example, in... Figure 4A In this configuration, the straight-line distance between the center of one of the two light-emitting elements 1132 and the center of the photoelectric sensor 1133 is approximately 3 mm. For example, the circumferential distance between the centers of two adjacent photoelectric detection units 1131 ranges from 10 to 15 mm. Another example is in... Figure 4A In this example, the center-to-center distance between two adjacent photoelectric detection units 1131 on the circumference is 12.5 mm. It should be noted that the word "approximately" indicates that this value can vary within a range of, for example, ±15%.
[0113] For example, in some examples, such as Figure 4A As shown, the number of photoelectric detection units 1131 is, for example, 6. Alternatively, the number of photoelectric detection units 1131 can be 2, 3, 4, 5, 7, etc., depending on the number of detection areas of the detection chip 1200. This embodiment is not limited to the number of photoelectric detection units 1131.
[0114] For example, in other examples, the photoelectric detection unit 1131 may also include a photoelectric sensor 1133 and a light-emitting element 1132, which can also realize the detection of the liquid to be detected in the detection area of the detection chip 1200. Alternatively, the photoelectric detection unit 1131 may also include multiple photoelectric sensors 1133 and multiple light-emitting elements 1132, and the multiple photoelectric sensors 1133 can detect different substances in the liquid to be detected. The embodiments disclosed herein are not limited to the number of light-emitting elements 1132 and photoelectric sensors 1133.
[0115] For example, the arrangement of multiple photoelectric sensors 1133 and multiple light-emitting elements 1132 in the photoelectric detection unit 1131 can be flexibly changed according to the detection index requirements of the liquid to be detected by the detection chip 1200. For example, multiple light-emitting elements 1132 can surround the photoelectric sensor 1133 in a star-like manner, or multiple light-emitting elements 1132 can be arranged in two rows on both sides of the photoelectric sensor 1133.
[0116] For example, Figure 5A This is a schematic diagram illustrating the detection principle of the analyzer provided in the above embodiments of this disclosure. Figure 5A As shown, the light-emitting element 1132 generates an optical signal. Light of a specific intensity (incident light) emitted from the light-emitting element 1132 is transmitted to the chip placement structure 1120, thereby reaching the detection chip 1200 placed on the chip placement structure 1120. The light reflected from the detection area (the detection sample) of the detection chip 1200 is then received by the photoelectric sensor 1133. The photoelectric sensor 1133 receives the optical signal (reflected light) and converts it into an electrical signal. The intensity of the optical signal received by the photoelectric sensor 1133 can be obtained from the electrical signal.
[0117] For example, in other examples, the light-emitting element 1132 may also be configured as a single element, that is, the light emitted by the light-emitting element 1132 is used as incident light to illuminate the detection area of the detection chip 1200. The detection principle of the embodiments of this disclosure is not limited to the number of light-emitting elements 1132.
[0118] The absorbance value of the liquid to be tested is calculated according to the following formula:
[0119] (1)
[0120] In the above formula, I0 is the incident light intensity of the detection chip, I is the reflected light intensity of the detection chip, and A is the absorbance value. The content of a specific substance in the liquid to be detected is linearly related to the absorbance value. When incident light of a certain wavelength is incident on the detection area of the detection chip 1200, the liquid to be detected in the detection area absorbs part of the light and then reflects it. The intensity of the absorbed light is linearly related to the content of the substance in the liquid to be detected in the detection area. After the reflected light is received by the photoelectric sensor 1133, an electrical signal is obtained. The intensity of the reflected light can be obtained according to the magnitude of the electrical signal. The absorbance value is obtained by using formula (1) with the intensity of the reflected light and the intensity of the incident light.
[0121] For example, in some cases, the light-emitting element 1132 and photoelectric sensor 1133 of the analyzer 1100 need to be calibrated to ensure the stability of the light source of the analyzer 1100. A standard grayscale plate is used to calibrate the light emitted by the light-emitting element 1132 of the analyzer 1100. This standard grayscale plate is placed on a chip placement structure. The absorbance value of the standard grayscale plate for the incident light from the light-emitting element is a known standard absorbance value. The absorbance value obtained by the analyzer 1100 after detecting the standard grayscale plate is compared with the standard absorbance value. The light emitted by the light-emitting element 1132 of the analyzer 1100 is calibrated based on the comparison result.
[0122] For example, a liquid with known types and amounts of substances can be used as a calibration test sample. The analyzer 1100 detects the absorbance value of this calibration test sample to obtain... Figure 5B The coordinates of the absorbance value A and the substance content C shown are as follows: points D1, D2, D3, D4, and D5. The absorbance value A and the substance content C have a linear relationship. A standard curve is obtained by linearly fitting these five points. It should be noted that... Figure 5B The five points shown are just an example. Multiple points can be obtained using various test samples to obtain a standard curve. This disclosure is not limited to the specific process of obtaining the standard curve.
[0123] For example, in some cases, the absorbance value obtained from the analyzer's detection of the liquid being tested is used as the input. Figure 5B The standard curve showing absorbance value A versus substance content C allows us to obtain the substance content corresponding to the absorbance value of the liquid being tested. By detecting the liquid being tested in multiple detection areas of the detection chip 1200, the content of various substances in the liquid being tested can be obtained.
[0124] For example, in some examples, the light-emitting element 1132 is a light-emitting diode (LED), and the photoelectric sensing device 1133 is a photo-diode (PD), such as a silicon photodiode. LEDs can emit light of specific wavelengths (e.g., infrared, red, green, etc.), and the specific wavelength of the LED can be selected according to the type of substance being detected. LEDs located in different photoelectric detection units 1131 emit light of different wavelengths, thus enabling the detection of multiple substances through multiple photoelectric detection units 1131. For example, a photoelectric detection unit 1131 can select a light-emitting element that emits light at a wavelength of 630 nm to detect the content of lactose and fat in the liquid being tested. This allows the photoelectric detection unit 1131 to obtain the maximum absorption peak of light at a wavelength of 630 nm, maximizing its receiving efficiency and improving detection accuracy. For example, the photoelectric detection unit 1131 can also be selected to emit light with a wavelength of 660 nm to detect the content of calcium and protein in the liquid to be tested. This allows the photoelectric detection unit 1131 to obtain the maximum absorption peak of light at a wavelength of 660 nm, thereby maximizing its receiving efficiency and improving detection accuracy. Alternatively, the photoelectric detection unit 1131 can be selected to emit light with a wavelength of 585 nm to detect the content of zinc in the liquid to be tested. This also allows the photoelectric detection unit 1131 to obtain the maximum absorption peak of light at a wavelength of 585 nm, maximizing its receiving efficiency and improving detection accuracy. Therefore, the photoelectric sensing device 1133 of the photoelectric detection unit 1131 of the analyzer provided in this embodiment can generate at least five detection signals (e.g., corresponding to lactose, fat, zinc, calcium, and protein, respectively).
[0125] For example, in other embodiments, depending on the reagents used in the detection area of the detection chip 1200, different wavelengths of light can be selected to detect various substances in the liquid to be tested. For example, in some examples, the lower part of the analyzer 1100 also includes an optical path assembly disposed in the first housing 1110 between the chip placement structure 1120 and the detection unit, and configured to transmit light emitted from at least one light-emitting element 1132 to the chip placement structure 1120, and to transmit light reflected from the detection chip 1200 placed on the chip placement structure 1120 to at least one photoelectric sensing device 1133. The optical path assembly can avoid interference between optical signals between different photoelectric detection units 1131, ensuring the reliability of the detection results.
[0126] For example, in some examples, such as Figure 4A and Figure 6AAs shown, the optical path assembly includes a split optical disc 1141, which is disposed on the detection unit. The split optical disc 1141 includes at least one set of light-transmitting holes 1142, which are evenly arranged on the same circumference of the split optical disc 1141 and correspond to a plurality of photoelectric detection units 1131 along the axial direction of the first housing 1110.
[0127] For example, in this example, such as Figure 6A As shown, the number of groups of light-transmitting holes 1142 is, for example, 6. Alternatively, the number of groups of light-transmitting holes 1142 can also be 2, 3, 4, 5, 7, etc., corresponding to the number of photoelectric detection units 1131. This embodiment is not limited to the number of groups of light-transmitting holes 1142.
[0128] For example, in some examples, each set of light-transmitting holes 1142 includes at least one light-emitting hole and at least one light-reflecting hole. The at least one light-emitting hole allows light emitted from the light-emitting element 1132 of the corresponding photodetector unit 1131 to pass through, and the at least one light-reflecting hole allows light reflected from the detection chip 1200 placed on the chip placement structure 1120 to pass through and be transmitted to the photosensitive device 1133 of the corresponding photodetector unit 1131. Figure 6A As shown, each set of light-transmitting holes 1142 includes two light-emitting holes 1143 and one light-reflecting hole 1144. The two light-emitting holes 1143 are located on both sides of the light-reflecting hole 1144. The light-emitting holes 1143 correspond to the light-emitting elements 1132 in the photoelectric detection unit 1131, and the light-reflecting hole 1144 corresponds to the photoelectric sensing device 1133 in the photoelectric detection unit 1131. The light emitted from the light-emitting element 1132 passes through the light-emitting holes 1143 and then enters the chip placement structure 1120. The light reflected from the detection chip 1200 placed on the chip placement structure 1120 passes through the light-reflecting hole 1144 and is received by the photoelectric sensing device 1133. The arrangement of the optical disc 1141 can avoid interference between optical signals between different photoelectric detection units 1131, ensuring the reliability of the detection results.
[0129] For example, in some examples, such as Figure 6BAs shown, the sidewall of the light-emitting through-hole 1143 of the light-emitting through-hole 1142 is inclined. The opening of the side of the light-emitting through-hole 1143 away from the photoelectric detection unit 1131 is larger than the opening of the side of the light-emitting through-hole 1143 near the photoelectric detection unit 1131. This increases the illumination area of the light emitted from the light-emitting element 1132 on the detection chip 1200. The angle between the sidewall of the light-emitting through-hole 1143 and the X direction (perpendicular to the axis of the splitting disc 1141) is α. The value of the angle α is, for example, about 130 degrees to 140 degrees, or for example, about 135 degrees. This allows the incident light passing through the through-hole 1143 to be emitted along the inclined surface of the long side of the through-hole 1143, which can better converge in the detection area of the detection chip 1200 and reduce the divergence of the incident light.
[0130] For example, the sidewall of the light-reflecting through-hole 1144 of the light-transmitting through-hole 1142 is beveled. The opening of the side of the light-reflecting through-hole 1144 away from the photoelectric detection unit 1131 is larger than the opening of the side of the light-reflecting through-hole 1144 closer to the photoelectric detection unit 1131. This avoids interference between the light emitted from the light-emitting element 1132 and the light reflected from the detection chip 1200 placed on the chip placement structure 1120. The angle between the sidewall of the light-reflecting through-hole 1144 and the X direction (perpendicular to the axis of the splitting disc 1141) is β. The value of the angle β ranges, for example, from approximately 115 degrees to 125 degrees, or, for example, approximately 120 degrees. It should be noted that the word "approximately" indicates that the value can vary within, for example, ±15%.
[0131] For example, in some examples, the light-emitting via 1143 is, for example, Figure 6A The rectangular aperture shown, the light-emitting through-hole 1143, has an opening size ranging from approximately 0.8 mm to 1 mm in both the circumferential and radial directions on the side near the photoelectric detection unit 1131. For example, the light-emitting through-hole 1143 has a circumferential and radial dimension of approximately 0.8 mm. The light-reflecting through-hole 1144 is, for example,... Figure 6A The diameter of the circular aperture 1144 shown is, for example, approximately 0.8 mm to 1 mm. As another example, the circumferential dimension of the opening of the light-reflecting aperture 1144 near the photoelectric detection unit 1131 is, for example, approximately 0.8 mm. It should be noted that the word "approximately" indicates that this value can vary within, for example, ±15%. Furthermore, depending on the processing requirements, the size of the light-emitting aperture 1143 and the diameter of the light-reflecting aperture 1144 can be selected to be slightly larger than 1 mm, provided that there is no optical crosstalk between two adjacent light-transmitting apertures 1142. This embodiment is not limited to the specific sizes of the light-emitting aperture 1143 and the light-reflecting aperture 1144.
[0132] For example, in some examples, such as Figure 6A As shown, the long side of the light emitting via 1143 ranges from approximately 3.5mm to 4.5mm, or for example, approximately 4mm. The short side of the light emitting via 1143 ranges from approximately 3mm to 3.4mm, or for example, approximately 3.2mm. It should be noted that the word "approximately" indicates that the value can vary within, for example, ±15%. By setting the light emitting via 1143 as a rectangular aperture, the incident light passing through the via 1143 is emitted along the inclined surface of the long side of the via 1143, allowing for better focusing in the detection area of the detection chip 1200 and reducing the divergence of the incident light.
[0133] For example, Figure 6C The light-transmitting aperture of the optical disc provided in another embodiment of this disclosure is along Figure 6A A schematic diagram of the cross-section EF in the diagram. (See attached diagram.) Figure 6C As shown, the light reflection aperture 1144 includes a first sub-reflection aperture 1144b near the first side (lower side in the figure, i.e., the side where the incident light enters) of the optical splitter 1141, and a second sub-reflection aperture 1144a near the second side (upper side in the figure, i.e., the side where the reflected light is reflected back) of the optical splitter 1141. For example, the diameter of the first sub-reflection aperture 1144b is smaller than the diameter of the second sub-reflection aperture 1144a. Therefore, light emitted from the light emission aperture 1143 can be blocked from entering the light emission aperture, causing detection errors.
[0134] For example, the diameter of the first sub-reflective aperture 1144b can range from approximately 0.8 mm to 1.2 mm. Alternatively, the diameter of the first sub-reflective aperture 1144b can be approximately 1 mm. Similarly, the diameter of the second sub-reflective aperture 1144a can range from approximately 1.4 mm to 1.8 mm. Another example is a diameter of the second sub-reflective aperture 1144a, which can be approximately 1.6 mm. It should be noted that the word "approximately" indicates that the value can vary within, for example, ±15%. This allows light emitted from the light-emitting aperture 1143 to be blocked from entering the light-emitting aperture, causing detection errors, without affecting the reflected light entering the first sub-reflective aperture 1144b.
[0135] For example, such as Figure 6C As shown, the upper surface of the optical disc 1141 (e.g., the surface near the second side) includes at least one boss 1144c. The boss 1144c protrudes obliquely towards the second side from one side of the two light-emitting apertures 1143 near the light-reflecting aperture 1144. A first sub-reflecting aperture 1144b is located within the boss 1144c to block light emitted from the light-emitting aperture 1143 from entering the light-emitting aperture and causing detection errors.
[0136] For example, such as Figure 6C As shown, the boss 1144c is annular and surrounds the first sub-reflective aperture 1144b. This blocks the light emitted from the light emitting aperture 1143 from entering the light emitting aperture, causing detection errors.
[0137] For example, such as Figure 6C As shown, the slope angle γ of the boss 1144c ranges from approximately 130° to 140°, and for example, the slope angle γ of the boss 1144c is approximately 135°. For example, the height by which the boss 1144c protrudes from the light-emitting through-hole 1143 ranges from approximately 0.4 to 0.6 mm, and for example, the height by which the boss 1144c protrudes from the light-emitting through-hole 1143 is approximately 0.5 mm. It should be noted that the word "approximately" indicates that the value can vary within, for example, ±15%. Therefore, the slope provided by the boss 1144c can shield the light emitted from the light-emitting through-hole 1143 from the first sub-reflective through-hole 1144b.
[0138] For example, in other examples, the shape of the light emitting aperture 1143 can also be a triangle, a circle, or a polygon, and the shape of the light reflecting aperture 1144 can also be a rectangle, a triangle, or a polygon. The embodiments disclosed herein are not limited to the shapes of the light emitting aperture 1143 and the light reflecting aperture 1144.
[0139] For example, in some examples, the optical disc 1141 also includes at least one second positioning hole. Figure 6A As shown, the optical disc 1141 includes three second positioning holes 1145, evenly distributed on the same circumference. The number of second positioning holes 1145 can also be two, four, etc., and this embodiment is not limited thereto. Figure 4A As shown, a first positioning hole 1303 of the detection circuit board 1302 is provided at a position opposite to the second positioning hole 1145 of the optical disc 1141. The first positioning hole 1303 and the second positioning hole 1145 of the detection circuit board 1302 are used for the installation and positioning of the optical disc 1141 and the detection circuit board 1302, so that the photoelectric detection unit 1131 corresponds to the light transmission hole 1142.
[0140] For example, in some examples, such as Figure 3 and Figure 6AAs shown, the optical disc 1141 also includes a limiting block 1146 disposed at the edge of the optical disc 1141. The limiting block 1146 extends into the chip placement structure 1120, thereby conforming to the shape of the detection chip 1200. When the detection chip 1200 is placed in the chip placement structure 1120, the position of the detection chip 1200 is fixed, so that the multiple detection areas of the detection chip 1200 correspond to the light transmission hole 1142 and the photoelectric detection unit 1131 of the optical disc 1141, respectively.
[0141] For example, in other examples, the limiting block 1146 may also be disposed on other structures of the analyzer 1100, such as on the first shielding plate 1301. As another example, the limiting block 1146 may also be replaced with other structures that can achieve alignment and cooperation with the detection chip 1200; the embodiments disclosed herein are not limited thereto.
[0142] For example, in other embodiments, the limiting block 1146 can be replaced with a positioning pin or a positioning hole, and a corresponding matching structure can be set on the detection chip 1200.
[0143] For example, in some examples, such as Figure 4A As shown, the lower part of the analyzer 1100 also includes a separating component 1150, such as a partition plate, located in the first housing 1110 and disposed between the optical path assembly and the chip placement structure 1120. That is, the separating component 1150 is located above the optical path assembly and below the chip placement structure 1120. The separating component 1150 includes a light-transmitting portion 1151, configured to allow light emitted from the light-emitting element 1132 of the photoelectric detection unit 1131 and light reflected from the detection chip 1200 placed on the chip placement structure 1120 to pass through. The detection chip 1200 is located above the separating component 1150, which is used to prevent the penetration of the liquid to be detected in the detection area of the detection chip 1200, and for example, can also provide protection for the optical path assembly below. In some other examples, the separating component 1150 disposed at the lower part of the analyzer 1100 is removable for easy replacement.
[0144] For example, in some examples, such as Figure 4A As shown, the light-transmitting portion 1151 of the separating component 1150 includes at least one transparent window 1152, which corresponds to a plurality of photoelectric detection units 1131, respectively, to allow light emitted from at least one light-emitting element 1132 of the corresponding photoelectric detection unit 1131 and light reflected from the detection chip 1200 placed on the chip placement structure 1120 to at least one photoelectric sensing device 1133 of the corresponding photoelectric detection unit 1131 to pass through.
[0145] For example, in this example, such as Figure 4AAs shown, the number of groups of transparent windows 1152 is, for example, 6. Alternatively, the number of groups of transparent windows 1152 can also be 2, 3, 4, 5, 7, etc., corresponding to the number of light-transmitting holes 1142. This embodiment is not limited to the number of groups of transparent windows 1152.
[0146] For example, in some examples, such as Figure 4A and Figure 4B As shown, each transparent window 1152 includes a first through-hole 1153, a first groove 1154, and a transparent sheet 1155. The diameter of the first through-hole 1153 is smaller than the diameter of the first groove 1154. The first groove 1154 is located on the side of the separator assembly 1150 near the chip placement structure 1120 and is used to place the transparent sheet 1155. The transparent sheet 1155 is placed in the first groove 1154 to allow light emitted from the two light-emitting elements 1132 of the corresponding photoelectric detection unit 1131 and light reflected from the detection chip 1200 placed on the chip placement structure 1120 to the photoelectric sensing device 1133 of the corresponding photoelectric detection unit 1131 to pass through.
[0147] For example, the diameter of the transparent sheet 1155 can range from approximately 5.5 to 7 mm, or for example, approximately 6.3 mm. The thickness of the transparent sheet 1155 can range from approximately 0.3 to 0.7 mm, or for example, approximately 0.5 mm. A smaller thickness of the transparent sheet 1155 is more conducive to light transmission, but this disclosure is not limited to this. For example, the diameter of the first through-hole 1153 can range from approximately 3 to 3.8 mm, or for example, approximately 3.4 mm. It should be noted that the word "approximately" indicates that the value can vary within, for example, ±15%. Therefore, the diameter of the first through hole 1153 can be selected so that the light incident from the light emitting through holes 1143 on both sides of the light reflecting through hole 1144 can be better focused in the detection area of the detection chip 1200, reducing the divergence of the incident light and improving detection accuracy.
[0148] For example, in some examples, the transparent sheet 1155 can be a glass sheet or transparent acrylic, etc.
[0149] For example, in other examples, the light-transmitting portion 1151 can also be other light-transmitting structures, such as a structure formed by a light-transmitting hole and a transparent sheet 1155, or a structure formed by removing the transparent sheet 1155 from the transparent window 1152. The embodiments disclosed herein are not limited to the specific structure of the light-transmitting portion 1151.
[0150] For example, in other examples, the separator 1150 may be an entirely transparent structure without the transparent window 1152. For instance, the separator 1150 may be made of a transparent material, thereby allowing light emitted from the light-emitting element 1132 of the photoelectric detection unit 1131 and light reflected from the detection chip 1200 placed on the chip placement structure 1120 to the photoelectric sensing device 1133 of the corresponding photoelectric detection unit 1131 to pass through, while preventing leakage of the liquid to be detected from the detection chip 1200. This disclosure is not limited to these embodiments.
[0151] In some other examples, the separator component 1150 may be omitted, and a transparent window may be provided on the light-transmitting hole of the split optical disc 1141. In this case, the split optical disc 1141 can also prevent the liquid to be detected from penetrating the detection area of the detection chip 1200.
[0152] For example, in some examples, such as Figure 4A As shown, the separating assembly 1150 also includes a plurality of positioning posts 1156 disposed on the side of the separating assembly 1150 near the split optical disc 1141. For example, the separating assembly 1150 includes three positioning posts 1156, which correspond to the positioning holes 1145 of the split optical disc 1141 and the positioning holes 1303 of the detection circuit board 1302. Furthermore, the positioning posts 1156 of the separating assembly 1150 are installed in the positioning holes 1145 of the split optical disc 1141 and the positioning holes 1303 of the detection circuit board 1302, thereby fixing the separating assembly 1150, the split optical disc 1141, and the detection circuit board 1302, and ensuring that the light-transmitting portion 1151 of the separating assembly 1150, the light-transmitting hole 1142 of the split optical disc 1141, and the photoelectric detection unit 1131 correspond in the axial direction of the first housing 1110.
[0153] For example, in other examples, the second positioning hole 1145 is disposed on the separator assembly 1150, and the positioning post 1156 is disposed on the split optical disc 1141. The positioning post 1156 extends to the upper and lower sides of the split optical disc 1141. The positioning post 1156 can also be installed in the positioning hole 1145 of the split optical disc 1141 and the positioning hole 1303 of the detection circuit board 1302, thereby fixing the separator assembly 1150, the split optical disc 1141, and the detection circuit board 1302. This disclosure is not limited to the installation method of the separator assembly 1150, the split optical disc 1141, and the detection circuit board 1302.
[0154] For example, in other examples, other methods can be used to fix the separator 1150, the optical disc 1141, and the detection circuit board 1302, such as using double-sided tape, using clips, etc.
[0155] For example, in some examples, such as Figure 7As shown, the analyzer 1100 also includes a second housing 1160 connected to the first housing 1110. The chip placement structure 1120 and the detection unit are disposed within the space enclosed by the first housing 1110 and the second housing 1160. For example, in this embodiment, as... Figure 2 and Figure 3 The detection unit shown is disposed on the detection circuit board 1302 and located within the first housing 1110. The first housing 1110 and the second housing 1160 are connected on the first side 1161, and the first housing 1110 and the second housing 1160 can be closed and opened relative to each other on the second side 1162 to place the detection chip 1200 on the chip placement structure 1120 or remove the detection chip 1200 from the chip placement structure 1120. It should be noted that, in the example shown in the figure, the first side 1161 is the side where the first housing 1110 and the second housing 1160 are connected to each other, and the second side 1162 is the side where the first housing 1110 and the second housing 1160 are opened and closed relative to each other, that is, the side where the detection chip 1200 is placed. The relative positions of the first side 1161 and the second side 1162 do not constitute a limitation on the embodiments of this disclosure. The first housing 1110 is roughly hemispherical. The shape of the opening at the bottom of the first housing 1110 is the same as the shape of the opening at the top of the second housing 1160, so that when the first housing 1110 and the second housing 1160 are closed, they can form a closed space that cannot be entered by external ambient light, which is beneficial to the detection of the analyzer 1100.
[0156] For example, in other examples, the shape of the second housing 1160 can also be, for example, a cuboid, etc. The opening shape of the second housing 1160 can be matched with the opening shape of the first housing 1110 to form a closed space. The embodiments disclosed herein are not limited thereto.
[0157] For example, in some examples, such as Figure 2 as well as Figure 7 As shown, the second housing 1160 is hinged to the first housing 1110 on the first side 1161. The second housing 1160 is configured to be closed to the first housing 1110 on the second side 1162, and to be opened to expose the chip placement structure 1120. The first side 1161 and the second side 1162 are disposed opposite each other.
[0158] For example, in some examples, such as Figure 2 As shown, the first housing 1110 and the second housing 1160 are hinged on the first side 1161 via a hinge shaft 1163. A spring (e.g., a torsion spring) may also be provided on the hinge shaft 1163 so that after the first housing 1110 and the second housing 1160 are opened on the second side, the second housing 1160 will tilt up under the elastic force of the spring.
[0159] For example, in some examples, such as Figure 8 As shown, the second housing 1160 also includes a second shielding plate 1304 connected to the lower side of the second housing 1160, for example, by snap-fit or screw connection. The second shielding plate 1304 and the first shielding plate 1301 in the first housing 1110 together form the accommodating space for the detection chip. The second shielding plate 1304 can block other stray light in the second housing 1160, avoiding interference from other light on the detection results.
[0160] For example, in some examples, such as Figure 3 as well as Figure 8 As shown, the first housing 1110 includes a first sub-opening / closing assembly 1181 disposed on the second side 1162, and the second housing 1160 includes a second sub-opening / closing assembly 1182 disposed on the second side 1162. The first sub-opening / closing assembly 1181 and the second sub-opening / closing assembly 1182 are configured to be able to engage and disengage from each other, so that the first housing 1110 and the second housing 1160 are respectively closed and opened. When the first housing 1110 and the second housing 1160 are opened, the detection chip 1200 is placed on the chip placement structure 1120. Then, the first housing 1110 and the second housing 1160 are closed, and the detection of the substance begins.
[0161] like Figure 3 , Figure 8 as well as Figure 9 As shown, the second sub-opening / closing assembly 1182 includes a first locking tongue 1183 and a second locking tongue 1184 in an elongated shape. The first locking tongue 1183 and the second locking tongue 1184 are paired and arranged approximately side-by-side in the second housing 1160. The first locking tongue 1183 and the second locking tongue 1184 can be fixed to the second cover plate 1304. The fixing method is, for example, screw connection. The first end 1185 of the first locking tongue 1183 and the first end 1186 of the second locking tongue 1184 protrude from the second cover plate 1304. The first sub-opening / closing assembly 1181 includes a groove 1187 and a latching member 1188, with the latching member 1188 located in the groove 1187. The first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 are configured to extend into the groove 1187 and engage with the latching member 1188 to close the first housing 1110 and the second housing 1160, and to disengage from the latching member to open the first housing 1110 and the second housing 1160.
[0162] For example, in some examples, such as Figure 8 As shown, the analyzer 1100 also includes a fixing member 1309, and the middle part of the first locking tongue 1183 and the middle part of the second locking tongue 1184 are fixed to the second shielding plate 1304 by the fixing member 1309.
[0163] For example, in some examples, the second sub-opening assembly 1182 also includes an elastic element disposed at the middle of the first latch 1183 and the middle of the second latch 1184 to elastically connect the first latch 1183 and the second latch 1184, and configured to apply an elastic force to tend to put the first latch 1183 and the second latch 1184 into a state that can be snapped onto the latching member 1188.
[0164] For example, in some examples, such as Figure 9 As shown, the elastic element is a torsion spring 1190, which applies an elastic force to bring the first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 closer together, so that the first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 are in a clamped state. The second end 1194 of the first latch 1183 and the second end 1195 of the second latch 1184 extend to the outside of the second housing 1160.
[0165] For example, in some examples, by reducing the opening distance between the second end 1194 of the first latch 1183 and the second end 1195 of the second latch 1184, the first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 are separated from the latch 1188 while in a state of being latched on the latch 1188, thereby opening the first housing 1110 and the second housing 1160.
[0166] For example, in some examples, the second sub-opening assembly 1182 further includes a switch disposed at the middle of the first latch 1183 and the middle of the second latch 1184, and connected to the first latch 1183 and the second latch 1184. The switch is configured to operate such that the first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 disengage from the latch member 1188 while in a state of being latched onto the latch member 1188.
[0167] For example, in some examples, such as Figure 9 As shown, the second sub-opening / closing assembly 1182 also includes micro switches 1305a and 1305b. Micro switch 1305a is located at the second end 1194 of the first latch 1183, and micro switch 1305b is located at the second end 1195 of the second latch 1184. One of the micro switches 1305a and 1305b is used to enable the switching function of the analyzer 1100, and the other is used to enable the control function of the analyzer 1100 to display the detection results. For example, pressing and holding micro switch 1305a turns on the analyzer 1100 and begins the detection of the detection chip 1200; pressing micro switch 1305a briefly turns off the analyzer 1100; pressing micro switch 1305b selects the detection result to be displayed.
[0168] For example, in some examples, such as Figure 9 As shown, the second sub-opening and closing assembly 1182 also includes a rotating shaft 1189, which connects the middle part of the first locking tongue 1183 and the middle part of the second locking tongue 1184, and a torsion spring 1190 is sleeved on the rotating shaft 1189.
[0169] For example, in some examples, such as Figure 10 As shown, a connector 1192 is provided in the middle of the first latch 1183 of the second sub-opening assembly 1182. The surface of the connector 1192 opposite to the second latch 1184 is inclined, forming a limiting trajectory 1191. The limiting trajectory 1191 is used to limit the opening angle of the first latch 1183 and the second latch 1184, so as to avoid the opening distance between the first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 being too small and the opening distance between the second end 1194 of the first latch 1183 and the second end 1195 of the second latch 1184 being too large. This would cause the second housing 1160 to open at an excessively large angle relative to the first housing 1110. For example, if the angle between the second housing 1160 and the first housing 1110 is greater than 90 degrees, the second housing 1160 would tip over in the direction away from the second side 1162, and the analyzer 1100 would be at risk of tipping over.
[0170] For example, in some examples, such as Figure 7 As shown, the analyzer 1100 also includes a display device 1170, which is disposed on the second housing 1160. The display device 1170 may be, for example, a liquid crystal display, an organic light-emitting diode (OLED) display, electronic paper, a digital tube, etc., for displaying the detection results of the analyzer 1100.
[0171] For example, in some examples, such as Figure 7 , Figure 8 as well as Figure 9 As shown, the analyzer 1100 also includes a silicone sleeve 1306, which is fitted onto the second end 1194 of the first locking tongue 1183 and the second end 1195 of the second locking tongue 1184, in order to achieve the effects of aesthetics, dust prevention, and preventing light from entering the second housing 1160.
[0172] For example, in some examples, such as Figure 9 As shown, light-shielding members 1193 are respectively provided on the first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 to block the light in the second housing 1160.
[0173] For example, in some examples, such as Figure 5AAs shown, the analyzer 1100 also includes a control device 1310, which is signal-connected to the photoelectric detection unit 1131 and the display device 1170. The control device 1310 is configured to receive the detection results from the photoelectric detection unit 1131 and send the results to the display device 1170, which can display the received results. For example, the control device may include a processor and a memory. The processor may be a central processing unit (CPU), a data processor (DSP), etc., and the memory may be a semiconductor memory, used to store computer code to be executed on the processor and to store data. The control device 1310 is also connected to a micro switch 1305a and a micro switch 1305b to realize the switching function of the analyzer 1100 and the function of controlling the display of the detection results on the display device 1170. For example, pressing and holding the micro switch 1305a turns on the analyzer 1100 and begins testing the detection chip 1200; pressing the micro switch 1305a briefly turns off the analyzer. By pressing the micro switch 1305b, the display content of the display device 1170 can be controlled, and the test results can be viewed on the display device 1170 according to the selection.
[0174] For example, in some examples, such as Figure 5A As shown, the analyzer 1100 also includes a sound-emitting device 1311 and a signal transmitting and receiving device 1312. The sound-emitting device 1311 is, for example, a speaker, which emits a reminder sound as needed. The signal transmitting and receiving device 1312 includes, for example, an antenna, a modem, etc., for communication, such as using Bluetooth, WIFI, or mobile communication (e.g., 2G / 3G / 4G / 5G, etc.). This allows the analyzer to send detection results to other devices (e.g., mobile terminals such as mobile phones and tablets, or servers), such as uploading detection results in real time to an application (APP) installed on a mobile terminal like a mobile phone; or to receive control signals from other devices to control the operation of the analyzer through a control device, such as collaborating with the analyzer 1100 through an application (APP) installed on a mobile terminal like a mobile phone. For example, in some examples, the analyzer 1100 also includes a temperature sensor for monitoring the ambient temperature of the analyzer 1100. Since some liquids to be tested have certain temperature requirements during detection, such as needing to be within a temperature range of approximately 25°C to 35°C, monitoring the ambient temperature of the analyzer 1100 ensures the accuracy of the detection results.
[0175] For example, in some examples, the analyzer 1100 may also include a humidity sensor for detecting the ambient humidity of the analyzer 1100. During the detection process, some liquids require specific humidity levels; for instance, the liquid reacts with the test strip in the chip's detection area, and if the humidity is too low, the test strip may fade, affecting the detection results. Controlling the ambient humidity during the detection process helps ensure the accuracy of the detection results.
[0176] For example, in some examples, such as Figure 3 As shown, the analyzer 1100 also includes a battery 1307, disposed within the first housing 1110. The battery 1307 powers various devices within the analyzer 1100 that require electrical energy, such as control devices, display devices, and detection units. For example, the battery 1307 can be a primary or secondary battery; secondary batteries may include nickel-metal hydride batteries, nickel-cadmium batteries, lead-acid batteries, lithium-ion batteries, etc. The analyzer 1100 provided in this embodiment has a simple structure and low power consumption, thus providing a longer standby time for user convenience. Furthermore, the analyzer 1100 can also use a power cord to provide power to various devices that require electrical energy. Depending on the needs of using the analyzer 1100, either battery power or direct power supply can be selected.
[0177] For example, in some examples, such as Figure 3 As shown, the analyzer 1100 also includes a counterweight 1308, which is disposed in the first housing 1110 and located below the battery 1307. The counterweight 1308 is used to shift the center of gravity of the analyzer 1100 downward, thereby making the analyzer 1100 more stable when placed on a horizontal surface. It also makes it less likely for the detection chip 1200 to shift when placed on the chip placement structure 1120, thus ensuring the reliability of the detection results.
[0178] Furthermore, in at least one embodiment, the analyzer can be small in size, simple in structure, and easy to operate, making it suitable for home use and enabling real-time monitoring of the content of various substances in liquids such as breast milk.
[0179] Another embodiment of this disclosure also provides an analyzer, such as Figure 11As shown, the analyzer includes a first housing 2110, a chip placement structure 2120, and a detection unit. The chip placement structure 2120 is disposed within the first housing 2110 and is used to place a detection chip 1200; the detection chip 1200 has at least one detection area. The detection unit is rotatably disposed within the first housing relative to the chip placement structure 2120, and is, for example, a photoelectric detection unit. This photoelectric detection unit includes, for example, at least one photoelectric detection unit 2132, or for example, a single photoelectric detection unit. The photoelectric detection unit 2132 is configured such that, when the detection chip 1200 is placed on the chip placement structure 2120, multiple detection areas of the detection chip 1200 can be detected separately by relative rotation with respect to the detection chip 1200. For example, the multiple detection areas of the detection chip 1200 can be detected separately by rotating the detection chip 1200 or rotating the photoelectric detection unit. For example, the photoelectric detection unit 2132 includes at least one light-emitting element and at least one photoelectric sensing device, or for example, only a photoelectric sensing device.
[0180] In one example, the photoelectric detection unit 2132 of the analyzer is rotatably disposed within the first housing 2110 relative to the chip placement structure 2120. The analyzer can detect multiple detection areas of the detection chip through one photoelectric detection unit, thereby detecting the content of various substances in the liquid to be tested within the detection chip. In this example, the same light-emitting element included in the photoelectric detection unit 2132 can emit light of different wavelengths as needed for corresponding detection of different samples.
[0181] The structural difference between this embodiment and the analyzer provided in the previous embodiments is that the detection unit in this embodiment is rotatable relative to the chip placement structure within the first housing, and the detection unit includes only at least one photoelectric detection unit. The structural differences between this embodiment and the previous embodiments will be described below.
[0182] For example, in some examples, such as Figure 11 As shown, the detection unit is mounted on the detection circuit board 2302. A central shaft 2400 is located at the center of the detection circuit board 2302. The analyzer also includes a rotary drive device 2500, which is connected to and controlled by a control device. The rotary drive device 2500 can be, for example, a servo motor, a stepper motor, etc. The other end of the central shaft 2400 is connected to the rotary drive device 2500, which drives the central shaft 2400 to rotate, thereby causing the photoelectric detection unit 2132 of the detection unit to rotate relative to the chip placement structure 2120.
[0183] For example, in some examples, at least one photodetector unit includes a photodetector unit, and the rotation drive is configured to drive the photodetector unit to rotate relative to the chip placement structure.
[0184] For example, in some examples, compared to the aforementioned embodiments, the analyzer in this embodiment can connect the optical path component's split optical disc and the separating component to the first housing instead of connecting them to the detection circuit board, ensuring that the light-transmitting holes of the split optical disc and the light-transmitting portions of the separating component correspond to the detection areas of the detection chip.
[0185] For example, in some examples, compared to the aforementioned embodiments, the analyzer in this embodiment can replace the light-transmitting hole of the optical disc and the light-transmitting part of the separating component with a set, corresponding to the detection unit. The optical disc and the separating component rotate together with the detection circuit board 2132, placing the detection chip 1200 on the chip placement structure 2120, while the position of the detection chip 1200 remains unchanged. For example, a limiting spring can be provided on the side wall of the chip placement structure, fixing the position of the detection chip 1200 when it is placed on the chip placement structure 2120.
[0186] For example, in some examples, the rotary drive 2500 receives a signal from the control device and controls the rotation angle of the photoelectric detection unit 2132 so that the photoelectric detection unit 2132 stops rotating when it reaches a position corresponding to the detection area of the detection chip 1200, and the photoelectric detection unit 2132 detects the substance content in that detection area. The control device receives an electrical signal from the photoelectric sensor of the photoelectric detection unit 2132 and rotates the photoelectric detection unit 2132 again to a position corresponding to another detection area of the detection chip 1200, and then begins to detect the substance content in that detection area. In this manner, the analyzer can sequentially detect the substance content in multiple detection areas of the detection chip 1200, thereby obtaining the content of multiple substances in the liquid to be tested.
[0187] This disclosure provides at least one embodiment of a detection system, which includes an analyzer as described in any of the foregoing embodiments and a detection chip, for example, provided as a kit. The detection chip is configured to be placed on the chip placement structure of the analyzer.
[0188] Figure 12A This is a schematic diagram of a detection chip provided in one embodiment of the present disclosure. The detection chip can be applied to the detection instrument of the above embodiment. Figure 12B This is a partial structural schematic diagram of the detection chip provided in the above embodiments of this disclosure; Figure 12C This is an exploded view of a detection chip provided in another embodiment of this disclosure.
[0189] like Figure 12A as well as Figure 12BAs shown, the detection chip includes a cover plate 1201 and a substrate 1203. The cover plate 1201 has a sample inlet 1202 and is tightly attached to the substrate 1203. The substrate 1203 is made of a transparent material to allow light emitted from the photoelectric detection unit 1131 in the analyzer 1100 to enter the detection chip 1200 and light reflected by the detection chip 1200 to be transmitted to the photoelectric detection unit 1131.
[0190] For example, in some examples, such as Figure 12B As shown, multiple microchannels 1205, multiple detection areas 1206, and a calibration area 1207 are disposed on the surface of the cover plate 1201 opposite to the substrate 1203. The detection chip includes five detection areas 1206. Each detection area 1206 is connected to one end of a microchannel 1205, and the other end of the microchannel 1205 extends to the sample inlet 1202 of the cover plate 1201, so that the liquid to be detected enters the detection area 1206 through the microchannel 1205. For example, the center of the calibration area 1207 and the centers of the multiple detection areas 1206 are equally spaced on the same circumference, and the detection areas 1206 and the calibration area 1207 correspond to the photoelectric detection units 1131 in the detection unit of the analyzer 1100, respectively. The calibration area 1207 is used to detect whether there is a detection chip 1200 on the chip placement structure 1120 in the system calibration analyzer 1100.
[0191] For example, when the detection chip 1200 is placed on the chip placement structure 1120, the photoelectric detection unit 1131 corresponding to the calibration area 1207 can receive reflected light, causing the photoelectric detection unit 1131 to output an electrical signal, thereby determining that there is a detection chip 1200 in the analyzer 1100 at this time. The control device can control the detection work of other photoelectric detection units 1131 according to the electrical signal. Conversely, when the detection chip 1200 is not placed on the chip placement structure 1120, the photoelectric detection unit 1131 corresponding to the calibration area 1207 can receive very weak reflected light, causing the photoelectric detection unit 1131 to have no electrical signal output, thereby determining that there is no detection chip 1200 in the analyzer 1100 at this time, and the analyzer 1100 does not perform detection.
[0192] A test strip placement area 1208 is provided in the detection area 1206, and the test strip is placed in the test strip placement area 1208. Furthermore, a detection through-hole 1209 is provided at the center of the detection area 1206. After the liquid to be tested enters the detection area 1206, it undergoes a color reaction with the test strip. The extent of the color reaction can be observed through the detection through-hole 1209, thereby determining whether the currently added liquid to be tested is evenly distributed in the detection area 1206. In addition, the detection through-hole 1209 can also accommodate excess liquid to be tested.
[0193] For example, in some examples, such as Figure 12BAs shown, the detection area 1206 of the detection chip 1200 is rhomboid. For example, the shape of the detection area 1206 can also be circular, elliptical, triangular, etc. This embodiment is not limited to the shape of the detection area 1206.
[0194] For example, in some examples, such as Figure 12A As shown, the detection chip 1200 also includes a sample introduction unit 1204. For example, the sample introduction unit has a through hole at the center and is petal-shaped. The through hole of the sample introduction unit 1204 is connected to the sample inlet 1202 of the cover plate 1201. The liquid to be tested is dripped into the sample introduction unit 1204, and then the liquid enters the detection area 1206 of the detection chip through the sample inlet 1202 of the cover plate 1201 and the microchannel 1205 to react with the test strip.
[0195] For example, in examples of other embodiments, such as Figure 12C As shown, the injection unit 1204 can also be cylindrical. This embodiment is not limited to the specific shape of the injection unit.
[0196] For example, in other examples, the number of detection areas 1206 may be 2, 3, 4, 6, 7, etc., and this disclosure is not limited thereto.
[0197] For example, calibration area 1207 in the detection chip is not mandatory; the detection chip may not have calibration area 1207. Figure 12C As shown in the example, the detection chip includes 6 detection areas 1206, but no calibration area 1207 has been set.
[0198] For example, in some examples, such as Figure 12C As shown, a detection light-transmitting hole 1210 is provided on the substrate 1203 at a position opposite to the detection through hole 1209 of the cover plate 1201, so as to allow the light emitted from the photoelectric detection unit 1131 in the analyzer 1100 to enter the detection chip 1200 and the light reflected by the detection chip 1200 to be transmitted to the photoelectric detection unit 1131.
[0199] For example, in some examples, using such Figure 1A and Figure 1B The analyzer shown detects the substance content of a liquid, and the detection process includes... Figure 13 The steps are shown.
[0200] Step S100: The liquid to be tested is dropped into the detection chip. After the liquid to be tested is evenly distributed in the detection area 1206 and the colorimetric reaction is complete, the detection chip 1200 can then be placed into the analyzer 1100.
[0201] Step S200: Open the first housing and the second housing, and place the detection chip. Reduce the opening distance between the second ends 1194 and 1195 of the first latch 1183 and the second ends 1195 of the second latch 1184 (bring the second ends 1194 and 1195 of the first latch 1183 and the second ends 1195 of the second latch 1184 closer to the middle). Separate the first ends 1185 of the first latch 1183 and the first ends 1186 of the second latch 1184 from the latching member 1188 while they are locked on it, thereby opening the first housing 1110 and the second housing 1160 of the analyzer 1100, and placing the detection chip 1200 into the chip placement structure 1120. This embodiment is not limited to the order of steps S100 and S200. For example, the detection chip 1200 can be placed in the chip placement structure 1120 before the liquid to be tested is added to the detection chip 1200; no specific limitation is made here.
[0202] Step S300: Close the first housing and the second housing, and turn on the analyzer for detection. Close the first housing 1110 and the second housing 1160, and then press and hold the micro switch 1305a. The analyzer 1100 starts detection; the control device 1310 receives the detection result of the photoelectric detection unit 1131 and sends the detection result to the display device 1170.
[0203] Step S400: Obtain the test results. After the analyzer 1100 finishes its test, the test results can be viewed on the display screen by pressing the micro switch 1305b. The test results, such as the test report, can also be sent to other devices via Bluetooth (e.g., the test report can be pushed to the user's software or app).
[0204] Step S500: Retrieve the detection chip and turn off the analyzer. Reopen the first housing 1110 and the second housing 1160 of the analyzer 1100, remove the detection chip 1200, close the first housing 1110 and the second housing 1160, and briefly press the micro switch 1305a to turn off the analyzer 1100.
[0205] The analyzer 1100 can simultaneously measure the content of multiple substances in liquids, such as breast milk, and display the test results in a short time (e.g., 2-3 minutes). The analyzer 1100 has advantages such as simple structure and ease of operation, and can serve as a small, handheld home testing device. Users can complete the entire testing process at home, and the test results can be uploaded in real time to a mobile application (APP) installed on a mobile terminal, such as a smartphone. This facilitates the provision of information to users, such as the analysis of the substance content of breast milk, and the provision of professional nutritional, dietary guidance, and clinical recommendations based on the analysis results.
[0206] Regarding the detection system and its analyzer in the above embodiments, since the detection unit of the analyzer includes multiple photoelectric detection units or at least one photoelectric detection unit that can rotate relative to each other, the analyzer can detect multiple detection areas of the detection chip through multiple photoelectric detection units, thereby detecting the content of multiple substances in the liquid to be detected in the detection chip.
[0207] Figure 14 This is a schematic diagram of an analyzer provided in another embodiment of the present disclosure. Embodiments of the present disclosure also provide an analyzer, and embodiments of the present disclosure can also be as follows: Figure 14 As shown in the illustration.
[0208] like Figure 14 As shown, the analyzer 3100 includes a detection module 3110 and a control module 3130. The detection module 3110 includes a chip placement structure 3120. The detection module 3110 is configured to, when a detection chip 1200 having at least one detection area 1206 (such as...) Figure 12B When the chip (as shown) is placed on the chip placement structure 3120, at least one detection area 1206 of the detection chip 1200 is detected. The control module 3130 is signal-connected to the detection module 3110 and configured to control the detection operation of the detection module 3110 and receive the detection results of the detection module 3110.
[0209] For example, in some examples, the chip placement structure 3120 is a space for placing the detection chip 1200 and can shield the ambient light when detecting the detection chip 1200. For example, the chip placement structure 3120 can be as follows: Figure 2 As shown in the structure, when the detection module 3110 includes a first housing 1110 and a second housing 1160, the chip placement structure 3120 is located in the first housing 1110 for placing the detection chip 1200. The first housing 1110 and the second housing 1160 can be opened and closed on one side to facilitate user placement and retrieval of the detection chip 1200, and to prevent interference from external light on the detection chip during the operation of the analyzer 3100. The chip placement structure 3120 is located on the upper surface of the first housing 1110 (e.g., from...). Figure 2 The opening (e.g., formed on the surface of the first shielding plate 1301) in the middle Figure 2The circular opening 1301a of the first shielding plate 1301 forms a recessed accommodating space in the first housing 1110. For example, the cross-section of this accommodating space is approximately circular. It should be noted that other shapes are also possible, such as rectangular, elliptical, etc. When the detection module 3110 only includes the first housing 1110, the upper surface of the first housing 1110 is made into a light-shielding plane, and an opening is made on the side of the first housing 1110, which communicates with the chip placement structure 3120. A stage can be added to the chip placement structure 3120. The stage can pop out from the opening in the chip placement structure 3120 to place the detection chip 1200 on the stage, and then push the stage into the chip placement structure 3120 to detect the detection chip 1200. It should be noted that the operation of the stage can be selected as a drawer type to shield ambient light when detecting the detection chip 1200.
[0210] For example, in some examples, the control module 3130 receives an electrical signal sent by the detection module 3110 and obtains a detection result based on the electrical signal. For example, the control device 3130 may have a processor and a memory, the processor may be a central processing unit (CPU), a data processor (DSP), etc., and the memory may be a semiconductor memory, etc., used to store computer code to be executed on the processor and to store data, etc.
[0211] For example, Figure 15 This is a schematic diagram illustrating an analysis provided for yet another embodiment of this disclosure. For example... Figure 15 As shown, the detection module 3110 includes at least one photoelectric detection unit 3131. The photoelectric detection unit 3131 can be of various types, for example, including but not limited to multiple photoelectric detection units 3131. These photoelectric detection units 3131 are configured to detect multiple detection areas 1206 of the detection chip 1200 respectively when the detection chip 1200 is placed on the chip placement structure 3120.
[0212] For example, in other examples, the detection module 3110 includes a plurality of photoelectric detection units 3131, which correspond to a plurality of detection areas 1206 of the detection chip 1200 (e.g., in the vertical direction, i.e., in the axial direction of the first housing 1110).
[0213] For example, in some examples, each photodetector unit 3131 includes at least one light-emitting element and at least one photosensitive device. Figure 15As shown, the photoelectric detection unit 3131 includes two light-emitting elements 3132 and one photoelectric sensor 3133. For example, the two light-emitting elements 3132 (e.g., symmetrically arranged) are located on either side of the photoelectric sensor 3133. This arrangement of the two light-emitting elements 3132 and the photoelectric sensor 3133 ensures that the light emitted by the light-emitting elements 3132 is uniformly incident into the detection area of the detection chip 1200. It also increases the intensity of the incident light provided by the two light-emitting elements 3132 and the intensity of the reflected light after reflection by the detection chip 1200, thereby improving the stability of the analyzer's detection. For example, light of a specific intensity emitted by the light-emitting elements 3132 (incident light) is transmitted to the chip placement structure 3120 and reaches the detection chip 1200 placed on the chip placement structure 3120. The light reflected from the detection area 1206 (the detection sample) of the detection chip 1200 is then received by the photoelectric sensor 3133. The photoelectric sensor 3133 receives the optical signal (reflected light) and converts it into an electrical signal. The control device 3130 can obtain the intensity of the light signal received by the photoelectric sensor 3133 based on the electrical signal.
[0214] For example, in other examples, the photoelectric detection unit 3131 may also include a photoelectric sensor 3133 and a light-emitting element 3132, which can also realize the detection of the liquid to be detected in the detection area 1206 of the detection chip 1200. Alternatively, the photoelectric detection unit 3131 may also include multiple photoelectric sensors 3133 and multiple light-emitting elements 3132, and the multiple photoelectric sensors 3133 can detect different substances in the liquid to be detected. The embodiments disclosed herein are not limited to the number of light-emitting elements 3132 and photoelectric sensors 3133.
[0215] For example, in some examples, the light-emitting element 3132 is a light-emitting diode (LED), and the photoelectric sensing device 3133 is a photo-diode (PD), such as a silicon photodiode. LEDs can emit light of specific wavelengths (e.g., infrared, red, green, etc.), and the specific wavelength of the LED can be selected according to the type of substance being detected. LEDs located in different photoelectric detection units 3131 emit light of different wavelengths, thus enabling the detection of multiple substances through multiple photoelectric detection units 3131. For example, a photoelectric detection unit 3131 can select a light-emitting element that emits light at a wavelength of 630 nm to detect the content of lactose and fat in the liquid being tested. This allows the photoelectric detection unit 3131 to obtain the maximum absorption peak of light at a wavelength of 630 nm, maximizing its receiving efficiency and improving detection accuracy. For example, the photoelectric detection unit 3131 can also be selected to emit light with a wavelength of 660nm to detect the content of calcium and protein in the liquid to be tested. This allows the photoelectric detection unit 3131 to obtain the maximum absorption peak of light with a wavelength of 660nm, thus maximizing its receiving efficiency and improving detection accuracy. Alternatively, the photoelectric detection unit 3131 can be selected to emit light with a wavelength of 585nm to detect the content of zinc in the liquid to be tested. This also allows the photoelectric detection unit 3131 to obtain the maximum absorption peak of light with a wavelength of 585nm, maximizing its receiving efficiency and improving detection accuracy. Therefore, the photoelectric sensing device 3133 of the photoelectric detection unit 3131 of the analyzer 3100 provided in this embodiment can generate at least five detection signals (e.g., corresponding to lactose, fat, zinc, calcium, and protein, respectively). The detection module 3110 can transmit multiple detection signals to the control module 3130, which processes the detection signals to obtain the corresponding detection results. The control module 3130 can also transmit the detection results to the display module 3170 (e.g., ...). Figure 15 As shown in the figure, the display module 3170 will be described in detail later) to display on the display module 3170. Therefore, the analyzer 3100 provided in this embodiment of the present disclosure can simultaneously detect multiple indicators (such as the content of lactose, fat, zinc, calcium and protein).
[0216] For example, in some examples, such as Figure 15 As shown, the analyzer 3100 also includes a beam splitter 3140. The beam splitter 3140 is disposed between the chip placement structure 3120 and at least one photoelectric detection unit 3131, and is configured to transmit light emitted from at least one light-emitting element 3132 to the chip placement structure 3120, and to transmit light reflected from the detection chip 1200 placed on the chip placement structure 3120 to at least one photoelectric sensor 3133. Figure 6AAs shown, the beam splitter 3140 can be implemented as a beam splitter 1141. The beam splitter 1141 includes at least one set of light-transmitting holes 1142, which are uniformly arranged on the same circumference of the beam splitter 1141. Each set of light-transmitting holes 1142 includes at least one light-emitting hole and at least one light-reflecting hole. The at least one light-emitting hole allows light emitted from the light-emitting element 3132 of the corresponding photodetector unit 3131 to pass through, and the at least one light-reflecting hole allows light reflected from the detection chip 1200 placed on the chip placement structure 3120 to pass through and be transmitted to the photodetector 3133 of the corresponding photodetector unit 3131. The two light-emitting holes 1143 are located on both sides of the light-reflecting hole 1144. The light-emitting holes 1143 correspond to the light-emitting elements 3132 in the photodetector unit 3131, and the light-reflecting holes 1144 correspond to the photodetector 3133 in the photodetector unit 3131. Light emitted from the light-emitting element 3132 passes through the light-emitting aperture 1143 and then enters the chip placement structure 3120. Light reflected from the detection chip 1200 placed on the chip placement structure 3120 passes through the light-reflecting aperture 1144 and is received by the photoelectric sensor 3133. The arrangement of the optical disc 1141 can avoid interference between optical signals between different photoelectric detection units 3131, ensuring the reliability of the detection results.
[0217] It should be noted that the optical splitter 1141 is an example of the optical splitter assembly 3140. The optical splitter assembly 3140 can also be selected as other optical path structures, and the embodiments disclosed herein are not limited thereto.
[0218] For example, in some examples, such as Figure 15 As shown, the analyzer 3100 also includes a separating component 3150. The separating component 3150 is disposed between the beam-splitting component 3140 and the chip placement structure 3120. The separating component 3150 includes a light-transmitting portion. The light-transmitting portion is configured to allow light emitted from at least one light-emitting element 3132 and light reflected from the detection chip 1200 placed on the chip placement structure 3120 to pass through. The separating component 3150 can be as follows: Figure 4AThe partition assembly 1150 is shown. The partition assembly 1150 includes a light-transmitting portion 1151 configured to allow light emitted from the light-emitting element 3132 of the photoelectric detection unit 3131 and light reflected from the detection chip 1200 placed on the chip placement structure 3120 to pass through. The detection chip 1200 is located above the partition assembly 3150, which is used to prevent the penetration of the liquid to be detected in the detection area of the detection chip 1200, and for example, to provide protection for the optical path components below. The light-transmitting portion 1151 of the partition assembly 3150 includes at least one transparent window 1152, corresponding to a plurality of photoelectric detection units 3131, to allow light emitted from at least one light-emitting element 3132 of the corresponding photoelectric detection unit 3131 and light reflected from the detection chip 1200 placed on the chip placement structure 3120 to at least one photosensitive device 3133 of the corresponding photoelectric detection unit 3131 to pass through.
[0219] For example, in some examples, such as Figure 15 As shown, the analyzer 3100 also includes a display module 3170. The display module 3170 is signal-connected to the control module 3130 and configured to receive and display the detection results from the detection module 3110 sent by the control module 3130. The display module 3170 can be, for example, a liquid crystal display, an organic light-emitting diode (OLED) display, electronic paper, a digital tube, etc., for displaying the detection results of the analyzer 3100. When the analyzer 3100 includes a second housing 1160 or a first housing 1110 (as shown in Figure 1), the display module 3170 can be disposed on the second housing 1160 or the first housing 1110.
[0220] For example, in some examples, such as Figure 15 As shown, the analyzer 3100 also includes a switch module 3160. The switch module 3160 is signal-connected to the display module 3170 and configured to control the content displayed on the display module 3170. The switch module 3160 can also implement the switching function of the analyzer 3100. For example, as... Figure 9 As shown, the switch module 3160 can be either a micro switch 1305a or a micro switch 1305b, or one of them, to enable the switching function of the analyzer 3100 and the function of controlling the display of the test results on the display module 3170. For example, pressing and holding the micro switch 1305a turns on the analyzer 1100 and begins the detection of the detection chip 1200; pressing the micro switch 1305a briefly turns off the analyzer. By pressing the micro switch 1305b, the display content of the display module 3170 can be controlled, and the test results can be viewed on the display module 3170 according to the selected settings.
[0221] For example, in some examples, such as Figure 15As shown, the analyzer 3100 also includes a signal transmitting and receiving device 3180. The signal transmitting and receiving device 3180 is connected to the control module 3130 and configured to upload the detection results of the detection unit 3110 to a mobile device, or to receive control signals from the mobile device and transmit the control signals to the control module 3130 to control the operation of the analyzer 3100. The signal transmitting and receiving device 3180 includes, for example, an antenna, a modem, etc., for communication, such as using Bluetooth, WIFI, mobile communication (e.g., 2G / 3G / 4G / 5G, etc.), thereby sending the detection results to other devices (e.g., mobile terminals such as mobile phones and tablets, or servers, etc.), for example, uploading the detection results in real time to an application (APP) installed on a mobile terminal such as a mobile phone; or receiving control signals from other devices to control the operation of the analyzer 3100 through the control device, for example, cooperating with the analyzer 3100 through an application (APP) installed on a mobile terminal such as a mobile phone.
[0222] The following points need to be explained:
[0223] (1) The accompanying drawings of the embodiments of this disclosure only involve the structures involved in the embodiments of this disclosure. Other structures can be referred to the general design.
[0224] (2) Where there is no conflict, the embodiments of this disclosure and the features in the embodiments can be combined with each other to obtain new embodiments.
[0225] The above are merely specific embodiments of this disclosure, but the scope of protection of this disclosure is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in this disclosure should be included within the scope of protection of this disclosure. Therefore, the scope of protection of this disclosure should be determined by the scope of the claims.
Claims
1. An analyzer, comprising: A chip placement structure for placing a detection chip, wherein the detection chip has at least one detection area. At least one photoelectric detection unit is configured to detect at least one detection area of the detection chip when the detection chip is placed on the chip placement structure, and each photoelectric detection unit includes at least one light-emitting element and at least one photoelectric sensing device. An optical path assembly is disposed between the chip placement structure and the at least one detection unit, and is configured to transmit light emitted from the at least one light-emitting element to the chip placement structure, and to transmit light reflected from the detection chip to the at least one photoelectric sensing device. The optical path assembly includes a split optical disc, which includes at least one set of light-passing holes. Each set of light-passing holes includes at least one light-emitting hole and at least one light-reflecting hole. The at least one light-emitting hole allows light emitted from the at least one light-emitting element to pass through, and the at least one light-reflecting hole allows light reflected from the detection chip placed on the chip placement structure to pass through and be transmitted to the at least one photoelectric sensing device. Wherein, at least one of the at least one set of light-transmitting holes has a sidewall that is at least partially inclined relative to the axial direction of the optical disc.
2. The analyzer according to claim 1, wherein, At least one of the light-transmitting holes in each group is a rectangular or circular hole.
3. The analyzer according to claim 2, wherein, The at least one light-emitting through-hole is a rectangular hole, and the at least one light-reflecting through-hole is a circular hole.
4. The analyzer according to claim 2, wherein, At least one sidewall of the rectangular hole is inclined relative to the axial direction of the optical disc.
5. The analyzer according to claim 1, wherein, At least one sidewall of the at least one light-emitting through-hole extending radially along the optical disc is a slope.
6. The analyzer according to claim 1, wherein, The two sidewalls of the at least one light-emitting through-hole extending radially along the optical disc are inclined relative to the axial direction of the optical disc, and the inclination directions of the two sidewalls are different.
7. The analyzer according to claim 5, wherein, The angle between the inclined plane containing the at least one sidewall of the at least one light-emitting through-hole and the axial direction perpendicular to the optical disc ranges from 130 degrees to 140 degrees.
8. The analyzer according to claim 1, wherein, The opening on the side of the at least one light-emitting aperture furthest from the at least one photoelectric detection unit is larger than the opening on the side of the at least one light-emitting aperture closest to the at least one photoelectric detection unit.
9. The analyzer according to claim 1, wherein, At least one sidewall of the at least one light-reflecting through-hole is inclined relative to the axial direction of the optical disc.
10. The analyzer according to claim 9, wherein, The angle between the inclined plane containing the at least one sidewall of the at least one light-reflecting through-hole and the axial direction perpendicular to the optical disc is in the range of 115 degrees to 125 degrees.
11. The analyzer according to any one of claims 1-10, wherein, The optical disc is set to be centrally symmetrical, and each of the at least one set of light-transmitting holes is also set to be centrally symmetrical.
12. The analyzer according to any one of claims 1-10, wherein, The optical disc is circular in shape, and the at least one set of light-transmitting holes includes multiple sets of light-transmitting holes, which are evenly distributed in a circle around the center of the optical disc.
13. The analyzer according to any one of claims 1-10, wherein, Each set of light-transmitting holes includes two light-emitting holes and one light-reflecting hole, with the two light-emitting holes positioned on opposite sides of the light-reflecting hole.
14. The analyzer according to claim 13, wherein, The two light-emitting apertures are symmetrically arranged on opposite sides of the one light-reflecting aperture.
15. The analyzer according to claim 14, wherein, The straight-line distance between the centers of two adjacent light-emitting apertures on the optical disc ranges from 5 mm to 8 mm, and the straight-line distance between the center of one of the two light-emitting apertures in each group of light-emitting apertures and the center of one light-reflecting aperture ranges from 2.5 mm to 4 mm.
16. The analyzer according to claim 1, wherein, The straight-line distance between the centers of two adjacent light-emitting apertures on the optical disc ranges from 5 mm to 8 mm, and the straight-line distance between the center of the light-emitting aperture in each group of light-emitting apertures and the center of the nearest adjacent light-reflecting aperture ranges from 2.5 mm to 4 mm.
17. The analyzer according to any one of claims 1-10, wherein, The optical disc further includes a limiting structure disposed at the edge of the optical disc and extending into the chip placement structure.
18. The analyzer according to claim 13, wherein, Each set of light-reflecting apertures includes a first sub-reflecting aperture located on the side of the optical disc furthest from the at least one photoelectric detection unit and a second sub-reflecting aperture located on the side of the optical disc closest to the at least one photoelectric detection unit.
19. The analyzer according to claim 18, wherein, The diameter of the first sub-reflective aperture is smaller than the diameter of the second sub-reflective aperture.
20. The analyzer according to claim 13, wherein, The surface of the optical disc away from the at least one photoelectric detection unit includes at least one boss, which protrudes obliquely from the side of the two light-emitting holes in each set of light-emitting holes that is closer to the light-reflecting hole, toward the side away from the at least one detection unit. The light-reflecting through-holes of the optical disc are located in the at least one boss in a corresponding manner to block light emitted from at least one light-emitting element of the corresponding photoelectric detection unit through the light-emitting through-holes.
21. The analyzer according to claim 20, wherein, Each of the at least one boss is annular. Each of the at least one boss surrounds one of the light-reflecting through holes in each set of light-transmitting holes.
22. The analyzer according to claim 20, wherein, The slope angle of the boss relative to the axial direction perpendicular to the optical disc ranges from 130 degrees to 140 degrees, and the height of the boss protruding relative to the light-reflecting through-hole ranges from 0.4 mm to 0.6 mm.
23. The analyzer according to claim 13, wherein, Each photoelectric detection unit in the at least one photoelectric detection unit includes two light-emitting elements and one photoelectric sensing device, and the two light-emitting elements are disposed on opposite sides of the one photoelectric sensing device; The two light-emitting apertures in each group of light-emitting apertures allow light emitted from the two light-emitting elements to pass through, and the one light-reflecting aperture allows light reflected from the detection chip placed on the chip placement structure to pass through and be transmitted to the one photoelectric sensing device.
24. The analyzer according to claim 23, wherein, The straight-line distance between the centers of two adjacent light-emitting elements ranges from 5 mm to 8 mm, and the straight-line distance between the center of one of the two light-emitting elements in the same photoelectric detection unit and the center of the photoelectric sensing device ranges from 2.5 mm to 4 mm.
25. The analyzer according to claim 1, wherein, The straight-line distance between the centers of two adjacent light-emitting elements ranges from 5 mm to 8 mm, and the straight-line distance between the center of the light-emitting element and the center of the nearest adjacent photoelectric sensor in each of the at least one photoelectric detection units ranges from 2.5 mm to 4 mm.
26. The analyzer according to claim 1, wherein, The at least one photoelectric detection unit includes multiple photoelectric detection units, which are arranged in a row.
27. The analyzer according to claim 23, further comprising: A separator component is disposed between the optical path component and the chip placement structure. The separating component includes a light-transmitting portion configured to allow light emitted from the at least one light-emitting element and light reflected from the detection chip placed on the chip placement structure to pass through.
28. The analyzer according to claim 27, wherein, The light-transmitting portion of the separating component includes at least one transparent window, corresponding to the at least one photoelectric detection unit, to allow light emitted from at least one light-emitting element of the corresponding photoelectric detection unit and light reflected from the detection chip placed on the chip placement structure to at least one photoelectric sensing device of the corresponding photoelectric detection unit to pass through.
29. The analyzer according to claim 28, wherein, The separating component also includes a substrate and at least one transparent sheet. The substrate includes at least one mounting through hole, and the at least one transparent sheet is embedded in the at least one mounting through hole to provide the at least one transparent window.
30. The analyzer according to claim 27, further comprising: A detection circuit board, wherein the photoelectric detection unit is disposed on the detection circuit board, and the detection circuit board includes a first positioning hole. The separating component includes a positioning post and the split disc includes a second positioning hole; alternatively, the separating component includes a second positioning hole and the split disc includes a positioning post. The positioning pins are inserted into the first positioning hole and the second positioning hole to connect the optical disc, the separating component, and the detection circuit board.
31. The analyzer according to any one of claims 1-10, further comprising a rotary drive device, wherein, The at least one photoelectric detection unit includes one photoelectric detection unit. The rotation drive device is configured to drive the photoelectric detection unit to rotate relative to the chip placement structure.
32. The analyzer according to any one of claims 1-10, wherein, The detection chip also has a calibration reaction area. When the detection chip is placed on the chip placement structure, before detecting the detection area of the detection chip, one of the at least one photoelectric detection unit is further configured to calibrate the calibration reaction area of the detection chip.
33. A detection system, comprising: The analyzer as described in any one of claims 1-32, and The detection chip is configured to be placed on the chip placement structure of the analyzer.
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