超高效液相色谱串联质谱法检测花生中18种塑化剂的方法
The ultra-high performance liquid chromatography-tandem mass spectrometry method has filled the technical gap in the detection of 18 plasticizers in peanuts, realizing an efficient and low-cost detection method that is suitable for safety risk assessment and quality supervision of plasticizers in peanuts.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- INST OF AGRI QUALITY STANDARDS & TESTING TECH HENAN ACAD OF AGRI SCI
- Filing Date
- 2023-05-29
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies lack effective liquid chromatography-mass spectrometry (LC-MS) methods for detecting 18 plasticizers in peanuts, and national standards do not cover grain and oil samples, resulting in insufficient detection methods.
Ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was employed using a Shim-pack XR-ODS column and an Intertsil μODS-4 delay column. The mobile phase was methanol-5 mmol/L ammonium acetate solution. The mass spectrometry conditions were positive mode electrospray ionization and multiple reaction monitoring (MRM). Acetonitrile extraction and low-temperature settling were combined with sample pretreatment to avoid small column purification, optimize collision energy and voltage, and install a delay column to reduce background interference.
It achieves efficient separation and detection of 18 plasticizers in peanuts, reduces analysis costs, and improves detection sensitivity and accuracy. It is suitable for safety risk assessment and quality supervision of plasticizers in large quantities of peanuts.
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Figure CN117665145B_ABST