A CMOS-based fluorinated liquid X-ray detector for breast DR

Abstract

This invention provides a CMOS-based fluorinated liquid X-ray detector for breast radiography, comprising: a Topmetal II chip, a base, a plastic device, a first PCB readout board, and a second PCB readout board. The Topmetal II chip is bonded to the upper surface of the base, and the plastic device is located above the base, covering the Topmetal II chip to form a seal. The base is mounted on the upper surface of the first PCB readout board, and the plastic device is filled with FC40 fluorinated liquid. The Topmetal II chip is electrically connected to the first PCB readout board via the base, and the first PCB readout board is electrically connected to the second PCB readout board. This invention uses fluorinated liquid as the detector material. By filling the plastic device with fluorinated liquid and sealing it with the Topmetal II chip, this liquid-chip bonding method avoids the problems of difficult coupling and high costs associated with solid material-chip bonding, and also provides a new approach for flexible detectors. Using fluorinated liquid as a sealing material results in stable performance and a longer service life for the detection system.

Description

Technical Field

[0001] This invention relates to the field of X-ray detection, and more particularly to a CMOS-based fluorinated liquid X-ray detector for breast DR. Background Technology

[0002] With the development of X-ray imaging technology, commercial breast cancer medical imaging screening technologies and equipment have been upgraded, including mammography, digital mammography (DM), digital breast tomosynthesis (DBT), and breast CT, which have been approved in recent years.

[0003] Currently, the detectors used in breast cancer medical applications are mainly amorphous silicon, amorphous selenium, and single-photon detectors. Amorphous silicon detectors, being indirect conversion type, are technologically mature and have a high market share, but their low-dose imaging performance (including sensitivity and spatial resolution) remains a bottleneck restricting the development of this type of traditional X-ray detector. Amorphous selenium, as a direct conversion type X-ray detector, is limited by storage temperature. Below its normal lower temperature limit (10°C), amorphous selenium may detach from the edges, with the likelihood increasing at lower temperatures. This causes artifacts in X-ray images, which gradually amplify during use. Single-photon counting X-ray detectors generally use cadmium zinc telluride or cadmium telluride as the detector material, but the difficulty in growing large-scale crystals makes it difficult to manufacture large-area X-ray detectors without sutures. Furthermore, the high cost also hinders their widespread application in medical X-ray imaging. Summary of the Invention

[0004] To solve the above-mentioned technical problems, the present invention provides a CMOS-based fluorinated liquid X-ray detector for breast DR, comprising: Topmetal II chip 1, base 4, plastic device 2, first PCB readout board 3.1 and second PCB readout board 3.2;

[0005] Topmetal II-Chip 1 is bonded to the upper surface of the base 4. The plastic device 2 is located above the base 4. The plastic device 2 covers the Topmetal II-Chip 1 to form a seal. The base 4 is installed on the upper surface of the first PCB readout board 3.1. The plastic device 2 is filled with FC40 fluorinated liquid.

[0006] TopmetalⅡ-Chip 1 is electrically connected to the first PCB readout board 3.1 via the base 4, and the first PCB readout board 3.1 is electrically connected to the second PCB readout board 3.2.

[0007] Preferably, Topmetal II-chip 1 has a 72*72 array of pixels with a pixel pitch of 83μm, a top-level window size of 15*15μm for each pixel, and a design noise target of 30e- for Topmetal II-chip 1.

[0008] Preferably, the upper surface of the plastic device 2 is a metal electrode.

[0009] Preferably, the base 4 is a ceramic base, and the lower surface of the base 4 has pins for fixing the base 4 to the upper surface of the first PCB readout board 3.1.

[0010] Preferably, the second PCB readout board 3.2 further includes: a power port 3.2.1 and a network cable port 3.2.2;

[0011] Power port 3.2.1 accepts DC 5V voltage, and network port 3.2.2 is electrically connected to the PC.

[0012] A CMOS-based fluorinated liquid X-ray detection method for breast DR, implemented based on the aforementioned CMOS-based fluorinated liquid X-ray detector for breast DR, includes:

[0013] S1: Connect TopmetalⅡ-chip 1 electrically to the first PCB readout board 3.1 via the pins of the base 4;

[0014] S2: Vertically fix the first PCB readout board 3.1 on the table;

[0015] S3: Place the first PCB readout board 3.1, the object under test, and the X-ray source on the table in sequence, so that the center of the X-ray source, the center of the object under test, and the center of TopmetalⅡ-chip 1 are on the same horizontal line;

[0016] S4: Connect the network cable port 3.2.2 of the second PCB reader board 3.2 to the PC, and connect the power port 3.2.1 to an external DC 5V voltage;

[0017] S5: Connect the metal electrode on the upper surface of the plastic device 2 to a -3kV high voltage;

[0018] S6: Turn off the X-ray source and enable TopmetalⅡ-chip1 to collect background data without X-rays;

[0019] S7: Turn on the X-ray source so that TopmetalⅡ-chip1 can collect background data under X-rays;

[0020] S8: The PC terminal uses background data under both non-ray and ray-supported conditions to draw a two-dimensional image of the measured object.

[0021] The present invention has the following beneficial effects:

[0022] This invention uses fluorinated liquid as the detector material. By filling a plastic device with fluorinated liquid and sealing it with a Topmetal II chip, this liquid-to-chip bonding method avoids the problems of difficult coupling and high costs associated with solid materials and chips. It also provides a new approach for flexible detectors. Using fluorinated liquid as a sealing material ensures stable performance, resulting in a longer lifespan for the detection system. The electrical connection between two PCB readout boards enables rapid and continuous sampling, leading to higher data detection efficiency. Attached Figure Description

[0023] Figure 1 This is a structural diagram of a CMOS-based fluorinated liquid X-ray detector for breast DR.

[0024] The realization of the objective, functional features and advantages of the present invention will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation

[0025] It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

[0026] Reference Figure 1 The present invention provides a CMOS-based fluorinated liquid X-ray detector for breast DR, comprising: Topmetal II chip 1, base 4, plastic device 2, first PCB readout board 3.1 and second PCB readout board 3.2;

[0027] Topmetal II-Chip 1 is bonded to the upper surface of the base 4. The plastic device 2 is located above the base 4. The plastic device 2 covers the Topmetal II-Chip 1 to form a seal. The base 4 is installed on the upper surface of the first PCB readout board 3.1. The plastic device 2 is filled with FC40 fluorinated liquid.

[0028] TopmetalⅡ-Chip 1 is electrically connected to the first PCB readout board 3.1 via the base 4, and the first PCB readout board 3.1 is electrically connected to the second PCB readout board 3.2.

[0029] Furthermore, the Topmetal II chip is a pixel array chip that can directly collect space charge using the top metal layer.

[0030] Topmetal II-Chip 1 has a 72*72 array of pixels with a pixel pitch of 83μm. The top window size of each pixel is 15*15μm. The design noise target of Topmetal II-Chip 1 is 30e-.

[0031] Good spatial resolution can be achieved by setting the pixel pitch to 83μm.

[0032] Furthermore, the upper surface of the plastic device 2 is a metal electrode.

[0033] Specifically, to ensure the detector can be used stably for a long time and to prevent the fluorinated liquid from evaporating, the Topmetal II chip and the fluorinated liquid are sealed by plastic device 2.

[0034] The height of the FC40 fluorinated liquid in the plastic device 2 is 2mm, and the metal electrode on the upper surface of the plastic device 2 is used to apply a high voltage electric field to the FC40 fluorinated liquid.

[0035] FC40 fluorinated liquid is a colorless and transparent liquid with good chemical inertness, is not prone to corrosion, and can guarantee strong electrical insulation and thermal conductivity with low surface tension.

[0036] Furthermore, the base 4 is a ceramic base, and the lower surface of the base 4 has pins for fixing the base 4 to the upper surface of the first PCB readout board 3.1.

[0037] Furthermore, the second PCB readout board 3.2 also includes: a power port 3.2.1 and a network cable port 3.2.2;

[0038] Power port 3.2.1 accepts DC 5V voltage, and network port 3.2.2 is electrically connected to the PC.

[0039] Specifically, the PC-side system drives the entire detection system to perform detection tasks via program commands.

[0040] This invention provides a CMOS-based fluorinated liquid X-ray detection method for breast DR, implemented based on the CMOS-based fluorinated liquid X-ray detector for breast DR as described above, comprising:

[0041] S1: Connect TopmetalⅡ-chip 1 electrically to the first PCB readout board 3.1 via the pins of the base 4;

[0042] S2: Vertically fix the first PCB readout board 3.1 on the table;

[0043] S3: Place the first PCB readout board 3.1, the object under test, and the X-ray source on the table in sequence, so that the center of the X-ray source, the center of the object under test, and the center of TopmetalⅡ-chip 1 are on the same horizontal line;

[0044] S4: Connect the network cable port 3.2.2 of the second PCB reader board 3.2 to the PC, and connect the power port 3.2.1 to an external DC 5V voltage;

[0045] S5: Connect the metal electrode on the upper surface of the plastic device 2 to a -3kV high voltage;

[0046] S6: Turn off the X-ray source and enable TopmetalⅡ-chip1 to collect background data without X-rays;

[0047] S7: Turn on the X-ray source so that TopmetalⅡ-chip1 can collect background data under X-rays;

[0048] S8: The PC terminal uses background data under both non-ray and ray-supported conditions to draw a two-dimensional image of the measured object.

[0049] It should be noted that, in this document, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or system that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or system. Unless otherwise specified, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or system that includes that element.

[0050] The sequence numbers of the above embodiments of the present invention are for descriptive purposes only and do not represent the superiority or inferiority of the embodiments. In the unit claims listing several devices, several of these devices may be embodied by the same hardware item. The use of the terms first, second, and third, etc., does not indicate any order and can be interpreted as identifiers.

[0051] The above are merely preferred embodiments of the present invention and do not limit the scope of the patent. Any equivalent structural or procedural transformations made based on the description and drawings of the present invention, or direct or indirect applications in other related technical fields, are similarly included within the scope of patent protection of the present invention.

Claims

1. A CMOS-based fluorinated liquid X-ray detector for breast DR, characterized in that, include: TopmetalⅡ - Chip (1), base (4), plastic device (2), first PCB readout board (3.1) and second PCB readout board (3.2); Topmetal II-chip (1) is bonded to the upper surface of the base (4), and the plastic device (2) is located above the base (4). The plastic device (2) covers the Topmetal II-chip (1) to form a seal. The base (4) is installed on the upper surface of the first PCB readout board (3.1). The plastic device (2) is filled with FC40 fluorinated liquid. The Topmetal II chip (1) is electrically connected to the first PCB readout board (3.1) via the base (4), and the first PCB readout board (3.1) is electrically connected to the second PCB readout board (3.2).

2. The CMOS-based fluorinated liquid X-ray detector for breast DR according to claim 1, characterized in that, The Topmetal II-chip (1) has a 72*72 array of pixels with a pixel pitch of 83μm. The top window size of each pixel is 15*15μm. The design noise target of the Topmetal II-chip (1) is 30e-.

3. The CMOS-based fluorinated liquid X-ray detector for breast DR according to claim 1, characterized in that, The upper surface of the plastic device (2) is a metal electrode.

4. The CMOS-based fluorinated liquid X-ray detector for breast DR according to claim 1, characterized in that, The base (4) is a ceramic base, and the lower surface of the base (4) has pins for fixing the base (4) to the upper surface of the first PCB readout board (3.1).

5. The CMOS-based fluorinated liquid X-ray detector for breast DR according to claim 1, characterized in that, The second PCB readout board (3.2) also includes: a power port (3.2.1) and a network cable port (3.2.2); The power port (3.2.1) receives DC 5V voltage, and the network cable port (3.2.2) is electrically connected to the PC.

6. A CMOS-based fluorinated liquid X-ray detection method for breast DR, implemented based on the CMOS-based fluorinated liquid X-ray detector for breast DR as described in any one of claims 1-5, characterized in that, include: S1: Connect the Topmetal II chip (1) to the first PCB readout board (3.1) via the pins of the base (4); S2: Vertically fix the first PCB readout board (3.1) on the table; S3: Place the first PCB readout board (3.1), the object under test and the X-ray source on the table in sequence, so that the center of the X-ray source, the center of the object under test and the center of the Topmetal II-chip (1) are on the same horizontal line; S4: Connect the network cable port (3.2.2) of the second PCB readout board (3.2) to the PC, and connect the power port (3.2.1) to an external DC 5V voltage; S5: Connect the metal electrode on the upper surface of the plastic device (2) to a -3kV high voltage; S6: Turn off the X-ray source and enable TopmetalⅡ-chip (1) to collect background data without X-rays; S7: Turn on the X-ray source and enable TopmetalⅡ-chip (1) to collect background data under X-rays; S8: The PC terminal uses background data under both non-ray and ray-supported conditions to draw a two-dimensional image of the measured object.

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