Hemodialysis apparatus and storage medium

Abstract

The application discloses a hemodialysis device and a storage medium. The device comprises a memory and a processor. The memory stores a computer program, and the processor executes the computer program to realize the method. The method comprises the following steps: according to a received first theoretical flow of a user, feedback adjusting the rotating speed of a blood pump to make the blood flow of a blood circuit equal to the first theoretical flow; respectively feedback adjusting the rotating speed of a first liquid inlet pump, a second liquid inlet pump and a first waste liquid pump to make the flow of a first liquid inlet pipeline, a second liquid inlet pipeline and a first waste liquid pipeline respectively equal to a first liquid inlet flow, a second liquid inlet flow and a first waste liquid flow; respectively acquiring a first weight reduction value of a first liquid supplement bag, a second weight reduction value of a second liquid supplement bag and a first weight increase value of a waste liquid bag; judging whether a body fluid balance condition is met according to the values and determining whether to feedback adjust the rotating speed of the first waste liquid pump. In this way, the application can greatly reduce the risk of hemodialysis treatment of a patient while ensuring the treatment effect.

Description

Technical Field

[0001] This application relates to the field of hemodialysis technology, and more particularly to a hemodialysis device and storage medium. Background Technology

[0002] During hemodialysis treatment, the rates at which replacement fluid, dialysate, and waste fluid are introduced into the blood circuit have a significant impact on the efficiency and safety of the treatment. To maintain safety, some technologies individually adjust each pump to ensure the fluid flow rate in each branch matches the user's needs. However, this can easily lead to fluid imbalance between the total inflow and outflow, reducing the effectiveness of hemodialysis and increasing its risks. Summary of the Invention

[0003] Based on this, embodiments of this application provide a hemodialysis device and storage medium that can greatly reduce the risk of hemodialysis treatment for patients while ensuring treatment effectiveness.

[0004] In a first aspect, this application provides a hemodialysis device, comprising: a first waste pump, a first inlet pump, a second inlet pump, a first inlet line, a second inlet line, a first waste line, a first replenishment bag, a second replenishment bag, a first waste bag, a blood circuit, a blood pump, and a dialyzer; the blood circuit is disposed between the patient's artery and the patient's vein, the blood pump is disposed in the blood circuit, the blood input end and the blood output end of the dialyzer are connected in series in the blood circuit, the first waste line is connected between the waste output end of the dialyzer and the waste bag, and the first inlet line is connected between the blood circuit and the first waste line. Between the first fluid replenishment bags, the second fluid inlet line connects the dialysate inlet of the dialyzer to the second fluid replenishment bag. A first waste fluid pump is installed in the first waste fluid line, a first fluid inlet pump is installed in the first fluid inlet line, and a second fluid inlet pump is installed in the second fluid inlet line. The first fluid replenishment bag stores replacement fluid, and the second fluid replenishment bag stores dialysate. The hemodialysis device further includes a memory and a processor. The memory stores a computer program, and the processor executes the computer program to implement the following fluid balance regulation method for the hemodialysis device:

[0005] Based on the first theoretical flow rate received from the user, the rotation speed of the blood pump is adjusted to make the blood flow rate in the blood circuit equal to the first theoretical flow rate.

[0006] The rotational speeds of the first inlet pump, the second inlet pump, and the first waste pump are respectively adjusted by feedback to make the displacement fluid flow rate of the first inlet pipeline equal to the first inlet flow rate, the dialysate flow rate of the second inlet pipeline equal to the second inlet flow rate, and the waste liquid flow rate of the first waste liquid pipeline equal to the first waste liquid flow rate, wherein the first inlet flow rate, the second inlet flow rate, and the first waste liquid flow rate are all obtained based on the first theoretical flow rate;

[0007] The first weight reduction value of the replacement fluid in the first replenishment bag, the second weight reduction value of the dialysate in the second replenishment bag, and the first weight increase value of the waste liquid in the waste liquid bag are obtained respectively.

[0008] Based on whether the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance conditions, it is determined whether to adjust the speed of the first waste liquid pump according to feedback.

[0009] Secondly, this application provides a computer-readable storage medium storing a computer program that, when executed by a processor, causes the processor to implement the fluid balance regulation method for a hemodialysis device as described above.

[0010] This application provides a hemodialysis device and storage medium. The device allows for individual adjustment of the rotational speeds of the first influent pump, the second influent pump, and the first waste fluid pump, adjusting the flow rates of the replacement fluid, dialysate, and waste fluid to the user's desired range. Furthermore, based on the overall influent and outfluent volumes during hemodialysis treatment, it determines whether the device meets the fluid balance requirements and whether to adjust the rotational speed of the first waste fluid pump accordingly. This ensures the hemodialysis device maintains fluid balance, guarantees blood purification, and effectively improves the safety of hemodialysis treatment for patients. This application not only allows for feedback adjustment of the rotational speed of individual pumps, maintaining the accuracy and anti-interference capabilities of each pump's adjustment, but also considers the fluid balance between the overall influent and outfluent volumes of the hemodialysis device. This allows patients to maintain the balance between influent and outfluent volumes during hemodialysis treatment, ensuring reliability and anti-interference during the treatment and reducing the risks associated with hemodialysis. Attached Figure Description

[0011] Figure 1 This is a schematic diagram of the overall structure of an embodiment of the hemodialysis device of this application;

[0012] Figure 2 This is a schematic diagram of the tubing for hemodialysis treatment according to an embodiment of the hemodialysis device of this application;

[0013] Figure 3 This is a schematic flowchart of an embodiment of the fluid balance adjustment method for a hemodialysis device according to this application;

[0014] Figure 4 This is a schematic diagram of a dialysis treatment interface shown in one embodiment of the hemodialysis device of this application;

[0015] Figure 5 This is a schematic diagram showing the relationship between the rotational speed of the peristaltic pump and the fluid flow rate in the tubing, according to an embodiment of the hemodialysis device of this application.

[0016] Figure 6 This is a schematic diagram showing the change curve of liquid temperature over time in one embodiment of the hemodialysis device of this application. Detailed Implementation

[0017] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of this application.

[0018] The flowchart shown in the attached diagram is for illustrative purposes only and does not necessarily include all content and operations / steps, nor does it necessarily have to be performed in the order described. For example, some operations / steps can be broken down, combined, or partially merged, so the actual execution order may change depending on the actual situation.

[0019] In the following description, the use of suffixes such as "module," "part," or "unit" to denote elements is solely for the purpose of illustration in this application and has no inherent meaning in itself. Therefore, "module," "part," or "unit" may be used interchangeably.

[0020] Hemodialysis is a continuous blood purification therapy that replaces damaged kidney function. The working principle of hemodialysis is as follows: Blood is drawn from the body and guided to a dialyzer made of a semi-permeable membrane, through which small molecules (such as electrolytes and small nephrotoxic molecules) can pass. Blood flows in opposite directions on one side of the semi-permeable membrane, while dialysate flows on the other. Through diffusion and osmosis, the solute permeates from the side with a higher concentration to the side with a lower concentration, allowing medium and small molecule toxins and excess water in the blood to permeate into the dialysate. This removes toxins from the blood and excess water from the body, while simultaneously replenishing the patient's body with necessary substances and maintaining electrolyte and acid-base balance. Currently, hemodialysis is widely used in the treatment of various diseases, including uremia.

[0021] When a patient needs hemodialysis treatment, it is usually done through a hemodialysis machine. Figure 1 A schematic diagram of the structure of a hemodialysis device is shown. Figure 2 The diagram illustrates the tubing principle of hemodialysis treatment. The hemodialysis equipment mainly includes: a dialyzer, a blood circuit, an inlet tubing, a first waste fluid pump, a first inlet pump, a second inlet pump, a first inlet tubing, a second inlet tubing, a first waste fluid tubing, a first replenishment bag, a second replenishment bag, a waste fluid bag, a blood pump, and the dialyzer. The blood circuit includes an arterial tubing and a venous tubing, positioned between the patient's artery and vein. The blood pump is located within the blood circuit. The blood input and output ends of the dialyzer are connected in series within the blood circuit. The arterial tubing draws blood from the patient's artery via the blood pump, and after passing through the dialyzer via a semi-permeable membrane, it undergoes isotonic ion exchange with the dialysate to correct acid-base imbalances, remove toxins and excess water, and then returns to the patient's vein. The second fluid bag is used to pre-store dialysate. The rotation of the second inlet pump provides driving force to the second inlet tubing, which outputs the dialysate into the dialyzer. Within the dialyzer, the dialysate undergoes effective isotonic ion exchange with the blood through a semi-permeable membrane, thus achieving the therapeutic effect. After the exchange, the dialysate becomes waste fluid, which is output through the first waste fluid tubing to a waste fluid bag for storage. The blood, after the exchange, is then returned to the patient via venous tubing.

[0022] The first fluid bag is used to store replacement fluid, which contains substances needed by the human body and substances that have therapeutic effects on human diseases. The first inlet pump rotates to provide driving force to the first inlet line, so that the replacement fluid is slowly injected into the blood circuit at a certain flow rate, allowing the replacement fluid to mix directly with the blood and enter the human body, so as to correct acid-base imbalance and achieve the best disease treatment effect.

[0023] During hemodialysis treatment, the rate at which the blood circuit receives replacement fluid has a significant impact on the efficiency and safety of the treatment. Similarly, the rate at which the blood circuit outputs waste fluid also has a significant impact on the efficiency and safety of hemodialysis treatment. According to... Figure 2It is known that the flow rate of the replacement fluid in the first inlet line is determined by the rotational speed of the first inlet pump, the flow rate of the dialysate in the second inlet line is determined by the rotational speed of the second inlet pump, and the flow rate of the waste fluid in the first waste fluid line is determined by the rotational speed of the first waste fluid pump. To maintain the safety of hemodialysis treatment, the relevant technology adjusts each pump (including the first waste fluid pump, the first inlet pump, and the second inlet pump) individually to ensure that the fluid flow rate in each branch (including the first inlet line, the second inlet line, and the first waste fluid line) meets the user's flow requirements.

[0024] However, the method of individually adjusting each pump in related technologies causes individual changes in the fluid flow rate of each branch. This does not take into account the balance between the total influent and total outfluent volumes during hemodialysis treatment. The total influent volume includes the sum of the total volume of replacement fluid and dialysate entering the blood circuit, while the total outfluent volume includes the total volume of waste fluid output from the blood circuit. When each pump is individually controlled by feedback, this can easily cause fluid imbalance between the total influent and total outfluent volumes. For example, if the total influent volume is much greater than the total outfluent volume, the patient will receive too much fluid, reducing the effectiveness of hemodialysis treatment. If the total influent volume is much less than the total outfluent volume, the patient will experience severe dehydration, which will harm the patient's health.

[0025] Therefore, the relevant technologies cannot ensure the fluid balance regulation between the total inflow and total outflow of fluid in hemodialysis treatment. Hemodialysis equipment is prone to fluid imbalance, which reduces the accuracy of pump speed regulation and the safety of hemodialysis treatment.

[0026] This application provides a hemodialysis device and storage medium. The device allows for individual adjustment of the rotational speeds of the first influent pump, the second influent pump, and the first waste fluid pump, adjusting the flow rates of the replacement fluid, dialysate, and waste fluid to the user's desired range. Furthermore, based on the overall influent and outfluent volumes during hemodialysis treatment, it determines whether the device meets the fluid balance requirements and whether to adjust the rotational speed of the first waste fluid pump accordingly. This ensures the hemodialysis device maintains fluid balance, guarantees blood purification, and effectively improves the safety of hemodialysis treatment for patients. This application not only allows for feedback adjustment of the rotational speed of individual pumps, maintaining the accuracy and anti-interference capabilities of each pump's adjustment, but also considers the fluid balance between the overall influent and outfluent volumes of the hemodialysis device. This allows patients to maintain the balance between influent and outfluent volumes during hemodialysis treatment, ensuring reliability and anti-interference during the treatment and reducing the risks associated with hemodialysis.

[0027] The embodiments of this application will now be described in detail with reference to the accompanying drawings.

[0028] This application discloses a hemodialysis device, combined with... Figure 1 and Figure 2 The hemodialysis device includes: a first waste fluid pump, a first inlet pump, a second inlet pump, a first inlet line, a second inlet line, a first waste fluid line, a first replenishment bag, a second replenishment bag, a waste fluid bag, a blood circuit, a blood pump, and a dialyzer. The blood circuit is disposed between the patient's artery and vein, the blood pump is disposed in the blood circuit, the blood input end and the blood output end of the dialyzer are connected in series in the blood circuit, the first waste fluid line is connected between the waste fluid output end of the dialyzer and the waste fluid bag, the first inlet line is connected between the blood circuit and the first replenishment bag, the second inlet line is connected between the dialysate input end of the dialyzer and the second replenishment bag, the first waste fluid pump is disposed in the first waste fluid line, the first inlet pump is disposed in the first inlet line, the second inlet pump is disposed in the second inlet line, the first replenishment bag is used to store replacement fluid, and the second replenishment bag is used to store dialysate.

[0029] The hemodialysis device also includes a display screen, which can display various information related to the hemodialysis treatment process and can also receive various operation commands related to the hemodialysis treatment process output by the user on the display screen.

[0030] It should be noted that the "blood pump," "first waste liquid pump," "first inlet pump," and "second inlet pump" mentioned in this article all refer to peristaltic pumps. Peristaltic pumps are common electronic components in this field, and the principle of controlling the speed of a peristaltic pump is similar to that of controlling the speed of an electric motor. The peristaltic pump is installed in the pipeline. When the peristaltic pump rotates, it generates a driving force on the pipeline, forcing the liquid in the pipeline to flow according to a specific flow rate and direction. There is a corresponding relationship between the speed of the peristaltic pump and the flow rate of the liquid in the pipeline, such as... Figure 5 As shown, the flow rate of the liquid in the pipeline can be changed by adjusting the speed of the peristaltic pump; therefore, adjusting the speed of the peristaltic pump to a specific speed will allow the flow rate of the liquid in the pipeline to reach a specific flow rate.

[0031] The hemodialysis device further includes: a memory and a processor; the memory is used to store a computer program, and the processor is used to execute the computer program and, when executing the computer program, implement any of the following methods for regulating the fluid balance of the hemodialysis device.

[0032] See Figure 3 The fluid balance adjustment method for the hemodialysis device in this application embodiment includes the following steps:

[0033] Step S101: Based on the first theoretical flow rate input by the user, the rotation speed of the blood pump is adjusted to make the blood flow rate of the blood circuit equal to the first theoretical flow rate.

[0034] There are many ways for the user to input the first theoretical flow rate. Currently, the most common way is to input it through the display screen. In this case, before step S101, the following may also be included: when the blood pump is detected to be powered, the dialysis treatment interface is displayed on the display screen.

[0035] Specifically, the blood circuit is used to transport the patient's blood. When the blood pump is powered on, it indicates that the hemodialysis equipment is in the hemodialysis treatment stage, and the patient's blood is being treated with hemodialysis through the dialyzer. During the hemodialysis treatment stage, the first inlet line outputs replacement fluid to the blood circuit, the second inlet line outputs dialysate to the dialyzer, and the first waste fluid line outputs waste fluid to the waste fluid bag.

[0036] When the blood pump is detected to be powered on, it indicates that the hemodialysis equipment has been officially started. If the blood pump is detected to be de-powered, it indicates that the hemodialysis equipment has been shut down due to power failure. In this case, the blood circuit does not need to be connected to replacement fluid and dialysate, and the blood circuit does not need to output waste fluid.

[0037] Please combine Figure 4 During hemodialysis treatment, users can input relevant commands on the dialysis treatment interface to control the treatment process. The dialysis treatment interface can receive the user's initial theoretical flow rate.

[0038] The first theoretical flow rate represents the target flow rate that the user expects for the blood circuit. For example, the first theoretical flow rate is 13 ml / min. When the user sets the first theoretical flow rate, after feedback adjustment of the blood pump speed, the blood flow rate of the blood circuit gradually increases from 0 to the first theoretical flow rate, so that the blood circuit can transmit blood according to the first theoretical flow rate.

[0039] Optionally, the first theoretical flow rate can be any value between 10 ml / min and 15 ml / min, for example, 12 ml / min. The first theoretical flow rate can be set by the user based on previously accumulated clinical experience.

[0040] Step S102: Feedback adjustment is performed on the rotation speed of the first inlet pump, the rotation speed of the second inlet pump, and the rotation speed of the first waste pump, respectively, so that the displacement fluid flow rate of the first inlet pipeline is equal to the first inlet flow rate, the dialysate flow rate of the second inlet pipeline is equal to the second inlet flow rate, and the waste liquid flow rate of the first waste liquid pipeline is equal to the first waste liquid flow rate, wherein the first inlet flow rate, the second inlet flow rate, and the first waste liquid flow rate are all obtained based on the first theoretical flow rate.

[0041] The first inlet flow rate of the first inlet pipeline is determined based on the first theoretical flow rate; the second inlet flow rate of the second inlet pipeline is determined based on the first theoretical flow rate; and the first waste flow rate of the first waste liquid pipeline is determined based on the first theoretical flow rate. Wherein, the first inlet flow rate of the first inlet pipeline represents the user's desired replacement fluid flow rate, the second inlet flow rate of the second inlet pipeline represents the user's desired dialysate flow rate, and the first waste flow rate of the first waste liquid pipeline represents the user's desired waste liquid flow rate.

[0042] Optionally, the formula for calculating the first inlet flow rate can be: first inlet flow rate = first theoretical flow rate * 10%; the formula for calculating the second inlet flow rate can be: second inlet flow rate = first theoretical flow rate * 25%; and the formula for calculating the first waste liquid flow rate can be: first waste liquid flow rate = first theoretical flow rate * 30%.

[0043] The first inlet flow rate, the second inlet flow rate, and the first waste fluid flow rate are all calculated based on the first theoretical flow rate. Therefore, the replacement fluid flow rate of the first inlet line, the dialysate flow rate of the second inlet line, and the waste fluid flow rate of the first waste fluid line are all related to the blood flow rate of the blood circuit. The blood flow rate of the blood circuit is matched with the fluid flow rate of each branch (the "each branch" includes: the first inlet line, the second inlet line, and the first waste fluid line), which ensures that the patient's hemodialysis treatment process is in a normal state and prevents the blood in the blood circuit from being in a faulty flow state.

[0044] The rotational speed of the first inlet pump is adjusted by feedback so that the displacement fluid flow rate of the first inlet pipeline is equal to the first inlet flow rate; the rotational speed of the second inlet pump is adjusted by feedback so that the dialysate flow rate of the second inlet pipeline is equal to the second inlet flow rate; the rotational speed of the first waste pump is adjusted by feedback so that the waste liquid flow rate of the first waste liquid pipeline is equal to the first waste liquid flow rate.

[0045] By adjusting the speeds of the first inlet pump, the second inlet pump, and the first waste pump, the liquid can be transported through each branch according to the user's desired flow rate.

[0046] It should be noted that the rotational speed of each pump (including the blood pump, the first inlet pump, the second inlet pump, and the first waste pump) is adjusted by feedback. The specific feedback adjustment method can be PWM (Pulse Width Modulation) adjustment, which is a related technology. In the PWM adjustment method, the pump speed can be changed by adjusting the duty cycle of the pump drive voltage, thereby adjusting the flow rate of the pipeline corresponding to the pump to the user's desired flow rate. The rotational speed of each pump in this way has high adjustment flexibility.

[0047] Individual feedback adjustment of the speed of each pump can adjust the flow rate of each pipeline to the user's desired flow rate; however, this method of adjusting the flow rate of each pipeline individually does not take into account whether there is a fluid imbalance between the total fluid intake and total fluid output during hemodialysis treatment. There may be an imbalance between the total amount of fluid lost from the patient's blood and the total amount of fluid replenished to the patient's blood.

[0048] Step S103: Obtain the first weight reduction value of the replacement fluid in the first replenishment bag, the second weight reduction value of the dialysis fluid in the second replenishment bag, and the first weight increase value of the waste liquid in the waste liquid bag.

[0049] Individual feedback adjustment of the pump speed allows for the flow rate of each pipeline to be adjusted to the user's desired flow rate. However, this method of individually adjusting the flow rate of each pipeline does not take into account whether fluid imbalance occurs during hemodialysis treatment, specifically the total inflow and outflow of fluid. An imbalance may exist between the total amount of fluid lost from the patient's blood and the total amount of fluid replenished to the patient's blood. Therefore, the replacement fluid in the first refill bag is weighed to obtain a first weight reduction value; the dialysate in the second refill bag is weighed to obtain a second weight reduction value; and the waste fluid in the waste bag is weighed to obtain a first weight increase value.

[0050] Specifically, Figure 2 As shown, the hemodialysis device further includes: a first weighing sensor, a second weighing sensor, and a third weighing sensor; wherein the first replacement bag is disposed on the first weighing sensor, and the replacement fluid in the first replacement bag is weighed by the first weighing sensor to obtain a first weight reduction value. The first weight reduction value represents the weight reduction value of the replacement fluid in the first replacement bag per unit time, and the first weight reduction value also represents: the total weight of replacement fluid output to the blood circuit by the first inlet tubing per unit time; for example, if the first weight reduction value is 6g, it means that the first inlet tubing outputs 6g of replacement fluid to the blood circuit per unit time.

[0051] The second fluid replenishment bag is mounted on the second weighing sensor. The second weighing sensor weighs the dialysate in the second fluid replenishment bag to obtain the second weight reduction value. The second weight reduction value represents the weight reduction of the dialysate in the second fluid replenishment bag per unit time. The second weight reduction value also represents the total weight of dialysate output from the second inlet tubing to the blood circuit per unit time. For example, if the second weight reduction value is 20g, it means that the second inlet tubing outputs 20g of dialysate to the blood circuit per unit time.

[0052] The waste liquid bag is mounted on the third weighing sensor. The waste liquid in the waste liquid bag is weighed by the third weighing sensor to obtain the first weight increase value. The first weight increase value represents the weight increase of the waste liquid in the waste liquid bag per unit time. The first weight increase value also represents the total weight of waste liquid produced by the dialyzer per unit time. For example, if the first weight increase value is 23g, it means that a total of 23g of waste liquid is produced after mass exchange in the dialyzer per unit time. The first waste liquid pipeline outputs 23g of waste liquid to the waste liquid bag, and the waste liquid bag increases by 23g of waste liquid per unit time.

[0053] Step S104: Determine whether to adjust the speed of the first waste liquid pump based on whether the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance condition.

[0054] In this embodiment, the "first weight reduction value + second weight reduction value" represents the total influent volume during hemodialysis treatment, and the "first weight increase value" represents the total outfluent volume. Therefore, based on these three values, it is possible to determine whether the patient is in a state of fluid imbalance, and thus determine whether to adjust the speed of the first waste fluid pump. This ensures that the hemodialysis equipment maintains fluid balance, guarantees the effectiveness of blood purification, and effectively improves the safety of hemodialysis treatment. This embodiment not only allows for feedback adjustment of the speed of a single pump, maintaining the accuracy and anti-interference of feedback adjustment for each pump's speed, but also considers the fluid balance between the overall influent and outfluent volumes of the hemodialysis equipment. This allows the patient to maintain the balance between influent and outfluent volumes during hemodialysis treatment, ensuring the reliability and anti-interference of the treatment and reducing the risks associated with hemodialysis.

[0055] It should be noted that the speed of the first waste liquid pump is adjusted, but not the speed of the first or second inlet pump. This is because: First, when the speed of the first waste liquid pump is adjusted, the waste liquid flow rate in the first waste liquid pipeline will change, and the first weight increase value will also change accordingly. This is equivalent to directly changing the total output volume of the hemodialysis equipment. Therefore, by adjusting the speed of the first waste liquid pump, the difference between the total inlet volume and the total output volume of the hemodialysis equipment can be directly changed. Secondly, the rate of waste fluid produced by the dialyzer is related to the rotational speed of the first waste fluid pump. Furthermore, the rate of waste fluid produced by the dialyzer is highly adjustable during hemodialysis treatment. The adjustable range of the waste fluid flow rate in the first waste fluid line is large. When adjusting the waste fluid flow rate in the first waste fluid line, as long as the adjusted flow rate remains within the adjustable range, the impact on the patient's hemodialysis treatment effect is negligible and will not affect the safety of the hemodialysis treatment. Conversely, changes in the replacement fluid flow rate in the first inlet line and the dialysate flow rate in the second inlet line can compromise the safety of the patient's hemodialysis treatment. Therefore, it is not advisable to adjust the rotational speed of either the first or second inlet pump.

[0056] It should be noted that this embodiment uses weight change values ​​(including: first weight decrease value, second weight decrease value, and first weight increase value) to determine whether the total influent and total outfluent volumes of the hemodialysis device meet the fluid balance condition. Why not use flow rate change values ​​to directly determine whether the total influent and total outfluent volumes of the hemodialysis device meet the fluid balance condition? This is because weight change values ​​can be obtained very accurately through weighing sensors, but flow rate change values ​​are very prone to detection errors. Therefore, this embodiment uses weight change values ​​as the basis for determining the fluid balance condition.

[0057] The replacement fluid flow rate of the first inlet line is set to the first inlet flow rate, the dialysate flow rate of the second inlet line is set to the second inlet flow rate, and the waste fluid flow rate of the first waste fluid line is set to the first waste fluid flow rate. Only when the flow rates of each line are adjusted to the user's desired levels can it be determined whether the hemodialysis equipment meets the fluid balance requirements. If the flow rates of each line are not adjusted to the user's desired levels, it will be impossible to determine the actual inflow and outflow of fluid in the blood circuit during hemodialysis treatment, because the patient's hemodialysis treatment status has not yet reached the user's expected state.

[0058] In some embodiments, step S104, determining whether to adjust the rotation speed of the first waste pump based on whether the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance condition, may include: adjusting the rotation speed of the first waste pump when the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the fluid balance condition, wherein the fluid balance condition includes: |first weight reduction value + second weight reduction value - first weight increase value| < first preset value.

[0059] In this embodiment of the application, the fluid balance condition is as follows:

[0060] |First weight reduction + Second weight reduction - First weight increase| < First preset value; The first preset value is a pre-set value.

[0061] The "first weight reduction value + second weight reduction value" represents the total influent volume during hemodialysis treatment, the "first weight increase value" represents the total outfluent volume during hemodialysis treatment, and the "first preset value" represents the user-acceptable error in total fluid volume. This embodiment can determine whether a patient has fluid imbalance based on fluid balance conditions. Once fluid imbalance is detected (i.e., the fluid balance conditions are not met), the rotation speed of the first waste fluid pump is adjusted accordingly, and the waste fluid flow rate in the first waste fluid pipeline changes accordingly. After feedback adjustment, the waste fluid flow rate in the first waste fluid pipeline will not be equal to the first waste fluid flow rate. After feedback adjustment, neither the first nor the second weight reduction value will change, but the first weight increase value will change, potentially increasing or decreasing. The first weight increase value after feedback adjustment will satisfy the fluid balance conditions, and the patient's hemodialysis treatment will return to fluid balance, thus completing the automatic feedback adjustment function for the patient's fluid imbalance.

[0062] It should be noted that although the waste fluid flow rate of the first waste fluid pipeline after feedback adjustment will not be equal to the first waste fluid flow rate, this can still maintain the fluid balance between the total inflow and total outflow of the hemodialysis equipment, thus ensuring the safety of the patient's hemodialysis treatment.

[0063] In some embodiments, step S104, which involves adjusting the rotation speed of the first waste pump when the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the fluid balance condition, may further include: adjusting the rotation speed of the first waste pump when the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the first balance condition but meet the second balance condition, wherein the first balance condition includes: |first weight reduction value + second weight reduction value - first weight increase value| > second preset value, and the second balance condition includes: |first weight reduction value + second weight reduction value - first weight increase value| > first preset value; the second preset value is greater than the first preset value.

[0064] In some embodiments, the method may further include:

[0065] Step S105: When the first weight reduction value, the second weight reduction value, and the first weight increase value satisfy the first balance condition, control the blood pump, the first waste liquid pump, the first inlet pump, and the second inlet pump to stop, and issue a first prompt signal.

[0066] The fluid balance conditions include a first balance condition and a second balance condition. The first balance condition includes:

[0067] |First weight reduction + Second weight reduction - First weight increase| > Second preset value;

[0068] The second equilibrium condition includes:

[0069] |First weight reduction + Second weight reduction - First weight increase| > First preset value;

[0070] Wherein, the second preset value is greater than the first preset value.

[0071] Specifically, this embodiment distinguishes between a first balance condition and a second balance condition. The first balance condition is used to determine whether the hemodialysis equipment has experienced a fluid imbalance malfunction. When it is determined that the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the first balance condition, but the second balance condition is met, this indicates that the hemodialysis equipment has experienced a fluid imbalance. This situation is not a malfunction. By adjusting the rotation speed of the first waste fluid pump, the patient's hemodialysis treatment process can automatically return to a fluid balance state. This method not only ensures the safety of the patient's hemodialysis treatment but also allows for automatic feedback adjustment of the fluid imbalance in the hemodialysis equipment, enabling the patient's hemodialysis treatment to continue and ensuring the continuity of the treatment.

[0072] If the hemodialysis treatment process is determined to meet the first equilibrium condition, it indicates that the fluid imbalance during the hemodialysis treatment process is too great. In this case, the hemodialysis treatment process must be stopped, and the first warning signal should be issued. Once the user notices the first warning signal, they will immediately address the fluid imbalance fault of the hemodialysis equipment. In this situation, there is no need to adjust the speed of the first waste fluid pump, because this situation would endanger the safety of the patient's hemodialysis treatment. This situation is a fault state, and the patient needs to deal with the fault state immediately. Feedback adjustment is no longer of any practical significance.

[0073] Therefore, this embodiment differentiates between the first and second balance conditions, resulting in a lower risk during the patient's hemodialysis treatment.

[0074] It should be noted that the second preset value is a value set in advance, and users can set the second preset value based on their previously accumulated clinical technical experience. For example, the first preset value = 6g / min and the second preset value = 9g / min.

[0075] In some embodiments, step S104, which involves adjusting the rotational speed of the first waste pump when the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the fluid balance condition, may further include:

[0076] Sub-step S1041: When the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the first condition, increase the speed of the first waste liquid pump. The first condition includes: first weight reduction value + second weight reduction value - first weight increase value < first preset value.

[0077] Sub-step S1042: When the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the second condition, reduce the speed of the first waste liquid pump. The second condition includes: first weight increase value - first weight reduction value - second weight reduction value < first preset value.

[0078] First condition: First weight reduction value + Second weight reduction value - First weight increase value < First preset value.

[0079] Second condition: First weight increase - First weight decrease - Second weight decrease < First preset value.

[0080] Specifically, when the first condition is not met, the total influent volume of the hemodialysis equipment is much greater than the total outfluent volume, resulting in fluid imbalance in the patient. In this case, it is necessary to increase the speed of the first waste fluid pump so that the waste fluid flow rate in the first waste fluid pipeline also increases. The first weight increase value after feedback adjustment will also increase accordingly. By continuously increasing the speed of the first waste fluid pump until the hemodialysis treatment process meets the first condition, the feedback adjustment process of the speed of the first waste fluid pump is completed.

[0081] When the second condition is not met, the total output volume of the hemodialysis equipment is much greater than the total input volume, resulting in fluid imbalance in the patient. In this case, it is necessary to reduce the speed of the first waste fluid pump so that the waste fluid flow rate in the first waste fluid pipeline will also decrease, and the first weight increase value after feedback adjustment will also decrease accordingly. By continuously reducing the speed of the first waste fluid pump until the hemodialysis treatment process meets the second condition, the feedback adjustment process of the speed of the first waste fluid pump is completed.

[0082] Therefore, by adjusting the speed of the first waste fluid pump, this embodiment can restore the patient's hemodialysis treatment process to a state of fluid balance. This method greatly improves the control accuracy and sensitivity of feedback regulation during hemodialysis treatment.

[0083] In some embodiments, the method may further include:

[0084] Step S106: Obtain the first detection weight of the remaining liquid in the first replenishment bag and the second detection weight of the remaining liquid in the second replenishment bag, respectively.

[0085] Step S107: When the first detected weight is less than or equal to the preset safe weight, and / or the second detected weight is less than or equal to the preset safe weight, a second prompt signal is issued.

[0086] Specifically, when the blood pump is energized, the remaining fluid weight in the first infusion bag can be detected to obtain a first detected weight, and the remaining fluid weight in the second infusion bag can be detected to obtain a second detected weight. When it is determined that the first detected weight is less than or equal to a preset safe weight, and / or the second detected weight is less than or equal to the preset safe weight, a second prompt signal (e.g., an audible and visual prompt signal) is issued.

[0087] Specifically, the first replenishment bag, the second replenishment bag, and the waste bag each have a specific liquid capacity. For example, the first replenishment bag can only store a maximum of 1.5L of replacement fluid, the second replenishment bag can only store a maximum of 2L of dialysis fluid, and the waste bag can only store a maximum of 2L of waste liquid. Before hemodialysis treatment begins, the first fluid bag is pre-stored with a certain volume of replacement fluid, and the second fluid bag is pre-stored with a certain volume of dialysate. During hemodialysis treatment, the first fluid bag continuously outputs replacement fluid, and the second fluid bag continuously outputs dialysate. As a result, the remaining fluid weight in both the first and second fluid bags continuously decreases. The preset safety weight is used to determine whether the remaining fluid in the first and second fluid bags is insufficient. If the remaining fluid weight in either the first or second fluid bag is less than or equal to the preset safety weight, it indicates that at least one of the first and second fluid bags has insufficient remaining fluid, and a second warning signal is issued. Once the user notices the second warning signal, they will immediately check the remaining fluid status of both the first and second fluid bags, and the user is ready to replace the first and / or second fluid bags at any time.

[0088] Therefore, by weighing the remaining fluid in both the first and second fluid bags, preparations can be made in advance for bag replacement, ensuring the ease of operation during hemodialysis treatment.

[0089] In some embodiments, the method may further include:

[0090] Step S108: When the first increase in the weight of the waste bag after the speed of the first waste pump is adjusted by feedback is not within the preset safe weight range, a third prompt signal is issued.

[0091] Specifically, the preset safe weight range represents the allowable and adjustable range of the first weight increase of the waste fluid bag. After feedback adjustment, the waste fluid flow rate of the first waste fluid line may increase or decrease, and correspondingly, the first weight increase of the waste fluid bag will also increase or decrease. Only when the waste fluid flow rate of the first waste fluid line is within the preset safe flow rate range will the first weight increase of the waste fluid bag be within the preset safe weight range, and the rate of waste fluid produced by the dialyzer will be in a safe state. When the waste fluid flow rate of the first waste fluid line is not within the preset safe flow rate range, the rate of waste fluid produced by the dialyzer will be too high or too low, which will impair the safety of the patient's hemodialysis treatment. If the first weight increase of the waste fluid bag after feedback adjustment is not within the preset safe weight range, it indicates that the feedback adjustment process for the speed of the first waste fluid pump has malfunctioned. The feedback adjustment range for the speed of the first waste fluid pump is too large or too small. Once the user notices the third prompt signal (such as an audible and visual prompt signal), they will immediately address the malfunction in the feedback adjustment process of the hemodialysis equipment.

[0092] Optionally, there is a one-to-one correspondence between the preset safe weight range and the preset safe flow range. The preset safe weight range is related to the patient's physiological parameters, including age, gender, weight, and blood pressure. Users can directly set the preset safe weight range based on their clinical experience, for example, a preset safe weight range of 15g / min-20g / min. If the first weight increase of the waste bag after feedback adjustment is not within 15g / min-20g / min, it indicates a malfunction in the feedback adjustment process of the first waste pump.

[0093] This embodiment not only enables feedback adjustment of the rotation speed of the first waste fluid pump to bring the total influent and total outfluent volumes back to fluid balance during hemodialysis treatment, but also ensures the safety of the rotation speed of the first waste fluid pump during feedback adjustment. The feedback adjustment process of the hemodialysis equipment has a wider range of applicability and greater resistance to interference.

[0094] In some embodiments, the method may further include:

[0095] Step S109: When the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance condition, determine the first ratio between the first weight reduction value and the first weight increase value, and the second ratio between the second weight reduction value and the first weight increase value, respectively, and display the first ratio and the second ratio on the display screen of the hemodialysis device.

[0096] Specifically, when the first weight decrease, the second weight decrease, and the first weight increase all meet the fluid balance condition, it indicates that the patient's hemodialysis treatment is in a normal state. In this normal state, a first ratio and a second ratio are displayed on the screen. The first ratio represents the actual ratio between the first influent flow rate and the waste fluid flow rate of the first waste fluid line; the second ratio represents the actual ratio between the second influent flow rate and the waste fluid flow rate of the first waste fluid line. These two values ​​are of significant reference value. By viewing these values ​​on the screen, users can monitor the blood flow status in the blood circuit and further determine the safety of the patient's hemodialysis treatment.

[0097] In some embodiments, step S104, the feedback adjustment of the rotation speed of the blood pump, may include: when the rotation speed of the blood pump is adjusted, the rotation speed of the blood pump changes according to a set rotation speed amplitude.

[0098] Specifically, the speed of the blood pump changes according to the set speed range, which can improve the accuracy and sensitivity of the feedback adjustment of the blood pump speed. For example, if the set speed range is 2 r / min, the speed of the blood pump can be increased or decreased by 2 r / min. After the blood pump speed is adjusted by feedback, the blood flow in the blood circuit can be made equal to the first theoretical flow, thus accelerating the efficiency of the patient's hemodialysis treatment.

[0099] See Figure 2 In some embodiments, the hemodialysis device further includes: a first temperature sensor, a second temperature sensor, and a third temperature sensor; the first temperature sensor is disposed in the first inlet pipe, the second temperature sensor is disposed in the second inlet pipe, and the third temperature sensor is disposed in the first waste pipe.

[0100] At this point, the method may further include:

[0101] Step S110: When the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance condition, the first temperature sensor, the second temperature sensor, and the third temperature sensor are used to detect the replacement fluid temperature of the first inlet pipeline, the dialysate temperature of the second inlet pipeline, and the waste liquid temperature of the first waste liquid pipeline, respectively, to obtain the first detection temperature, the second detection temperature, and the third detection temperature.

[0102] Step S111: When the first detection temperature, the second detection temperature, and the third detection temperature do not meet the temperature balance condition, a fourth prompt message is issued. The temperature balance condition is: |(first detection temperature + second detection temperature) / 2 - third detection temperature| < first preset temperature, where the first preset temperature is a pre-set value.

[0103] Specifically, during hemodialysis treatment, both replacement fluid and dialysate are external liquids connected to the blood circuit, while waste liquid is the liquid lost from the blood. The first and second detection temperatures are the temperatures of the external liquids added to the blood circuit; the third detection temperature is the temperature of the blood lost from the blood circuit. This embodiment determines whether the first, second, and third detection temperatures meet the temperature balance condition. This allows it to determine whether the replacement fluid temperature, dialysate temperature, and waste liquid temperature will damage the blood temperature in the blood circuit. If the temperature balance condition is not met, it means that the temperature of the external liquid added to the blood circuit and the temperature of the blood lost from the blood circuit cannot reach temperature equilibrium. This can cause a sharp rise or fall in the blood temperature in the blood circuit, compromising the safety of the patient's hemodialysis treatment.

[0104] When the temperature of the external fluid added to the blood circuit and the temperature of the fluid lost from the blood circuit meet the temperature equilibrium condition, the blood temperature in the blood circuit remains within a safe fluctuation range, maintaining the patient's body temperature balance within the blood circuit, and the hemodialysis treatment process is safe. When the temperature of the external fluid added to the blood circuit and the temperature of the fluid lost from the blood circuit do not meet the temperature equilibrium condition, the blood temperature in the blood circuit exceeds the safe fluctuation range. In this case, a fourth warning message is issued, alerting the user that the patient's hemodialysis treatment process is in a state of body temperature imbalance. Upon noticing this fourth warning message, the user will immediately address the body temperature imbalance in the hemodialysis equipment.

[0105] For example, if the first preset temperature is 4℃, when |(first detection temperature + second detection temperature) / 2 - third detection temperature| < 4℃, then the temperature of the external liquid added to the blood circuit and the temperature of the liquid lost from the blood circuit will not cause drastic changes in the blood temperature of the blood circuit, and the patient can always maintain body temperature balance during hemodialysis treatment.

[0106] It should be noted that S110-S111 are executed only when the patient's hemodialysis treatment meets the fluid balance condition. If the patient's hemodialysis treatment does not meet the fluid balance condition, the speed of the first waste fluid pump needs to be adjusted accordingly. The waste fluid flow rate in the first waste fluid pipeline will change, and the temperature of the fluid lost from the blood circuit will change with the waste fluid flow rate. The waste fluid temperature detected by the third temperature sensor will also change. In this case, "determining whether the hemodialysis treatment meets the temperature balance condition" has no reference value.

[0107] In some embodiments, the method may further include:

[0108] Step S112: Plot the first curve of the first detected temperature changing with time, the second curve of the second detected temperature changing with time, and the third curve of the third detected temperature changing with time, and display them on the display screen.

[0109] Specifically, when three temperature sensors (including a first temperature sensor, a second temperature sensor, and a third temperature sensor) are used to detect the liquid temperature, the display screen of the hemodialysis equipment shows the curves of the liquid temperature detected by these three temperature sensors over time, such as... Figure 6As shown, users can see the first, second, and third change curves at any time. By viewing each curve on the display screen, users can see the temperature changes of the replacement fluid, dialysate, and waste fluid. These temperature changes can serve as a basis for judging the safety of the patient's hemodialysis treatment process, allowing users to more comprehensively monitor the blood flow status in the blood circuit.

[0110] See Figure 2 In some embodiments, the hemodialysis device further includes: a fourth temperature sensor disposed in the blood circuit; during the hemodialysis treatment phase, the fourth temperature sensor is used to detect the blood temperature in the blood circuit; the method may further include:

[0111] Step S113: Use the fourth temperature sensor to detect the blood temperature in the blood circuit to obtain the fourth detection temperature.

[0112] Step S114: Determine the first preset temperature based on the fourth detected temperature.

[0113] For example, the formula for calculating the first preset temperature can be: First preset temperature = Fourth detection temperature / 10.

[0114] For example, when the fourth temperature sensor detects a fourth temperature of 36℃, then the first preset temperature = fourth detection temperature / 10 = 3.6℃; the temperature balance condition is: |(first detection temperature + second detection temperature) / 2 - third detection temperature| < 3.6℃.

[0115] By setting the first preset temperature in the above manner, the temperature balance condition can be made more scientific and standardized. Based on the temperature balance condition, it is possible to accurately determine whether the patient's blood temperature is in a state of body temperature balance, thereby reducing the error in judging the body temperature balance state of blood temperature.

[0116] In some embodiments, the method may further include:

[0117] Step S115: When the continuous duration of the feedback adjustment of the rotation speed of the first waste liquid pump exceeds the preset safe duration, a fifth prompt signal is issued.

[0118] Specifically, when fluid imbalance occurs in the hemodialysis equipment, feedback adjustment of the speed of the first waste fluid pump is required. This embodiment limits the continuous duration of this feedback adjustment. A preset safe duration represents the maximum allowed continuous time for feedback adjustment of the first waste fluid pump's speed. If the continuous duration of feedback adjustment is too long, the patient's hemodialysis treatment cannot return to fluid balance, indicating a prolonged state of fluid imbalance during treatment, which compromises the safety of the hemodialysis process. Therefore, when the continuous duration of feedback adjustment exceeds the preset safe time, it indicates that the continuous duration of feedback adjustment of the first waste fluid pump's speed is too long. A fifth notification message will then alert the user that the feedback adjustment process of the first waste fluid pump has malfunctioned, prompting the user to immediately address the feedback adjustment fault in the hemodialysis equipment.

[0119] In some embodiments, before step S101, which involves feedback adjustment of the blood pump speed based on the received first theoretical flow rate input by the user, the following may be included:

[0120] Step S116: Detect the initial weight of the second replenishment bag and the initial weight of the waste bag.

[0121] Specifically, when the blood pump is detected to be energized, the initial weight of the second infusion bag and the initial weight of the waste bag are detected.

[0122] Step S117: Determine the initial total weight of the liquid in the hemodialysis device, wherein the initial total weight of the liquid is equal to the sum of the initial weight of the second replenishment bag and the initial weight of the waste bag.

[0123] Initial total weight of liquid = initial weight of the second replenishment bag + initial weight of the waste bag.

[0124] Specifically, the initial weight of the second replenishment bag represents the weight of the second replenishment bag in the initial stage, and the initial weight of the waste bag represents the weight of the waste bag in the initial stage; where the initial stage refers to the time when the second replenishment bag has not yet discharged dialysate, and the time when the waste bag has not yet been connected to waste liquid.

[0125] The method may further include:

[0126] Step S118: When the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance condition, detect the actual weight of the second fluid replenishment bag and the actual weight of the waste fluid bag.

[0127] Step S119: Determine the actual total weight of the liquid in the hemodialysis device, wherein the actual total weight of the liquid is equal to the sum of the actual weight of the second replenishment bag and the actual weight of the waste bag.

[0128] The actual total weight of the liquid = the actual weight of the second replenishment bag + the actual weight of the waste bag.

[0129] The actual total weight of the fluid in the hemodialysis equipment is calculated during the hemodialysis treatment phase; and the actual total weight of the fluid in the hemodialysis equipment is calculated when the hemodialysis treatment process is in a state of fluid balance; during the hemodialysis treatment phase, the second replenishment bag continuously outputs dialysate, and the waste fluid bag continuously receives waste fluid. The actual weight of the second replenishment bag decreases continuously over time, while the actual weight of the waste fluid bag increases continuously over time.

[0130] Step S120: When the weight difference between the actual total weight of the liquid and the initial total weight of the liquid is less than or equal to a first preset weight value, determine the cumulative weight reduction value of the replacement fluid in the first fluid replacement bag, and display the cumulative weight reduction value of the replacement fluid on the display screen of the hemodialysis device.

[0131] Step S121: When the weight difference between the actual total weight of the liquid and the initial total weight of the liquid is greater than the first preset weight value, a sixth prompt message is displayed on the display screen.

[0132] If the following condition is met: Actual total liquid weight - Initial total liquid weight ≤ First preset weight value, then the cumulative weight reduction of the replacement fluid in the first replenishment bag is calculated and displayed on the display screen. If the following condition is not met: Actual total liquid weight - Initial total liquid weight ≤ First preset weight value, that is, if the following condition is met: Actual total liquid weight - Initial total liquid weight > First preset weight value, then a sixth prompt message is displayed on the display screen.

[0133] The weight difference between the actual total weight of the fluid and the initial total weight of the fluid represents the increase in the total weight of the second replenishment bag and the waste fluid bag caused by the exchange of substances between blood and dialysate inside the dialyzer during hemodialysis treatment. Because of this exchange, excess water and harmful substances from the blood permeate into the waste fluid. Therefore, the actual total weight of the fluid gradually increases as the patient undergoes hemodialysis treatment, and it will always be greater than the initial total weight. The weight difference refers to the weight of substances lost by the patient's blood during hemodialysis treatment. The first preset weight value represents the maximum weight of substances lost by the patient's blood during hemodialysis treatment. If the actual total weight of the fluid minus the initial total weight of the fluid exceeds the first preset weight value, it indicates that the patient has lost too many substances and is highly susceptible to dehydration. In this case, a sixth warning message needs to be displayed on the screen. Upon noticing this message, the user will immediately take action to address the potential dehydration.

[0134] If the actual total weight of the fluid minus the initial total weight of the fluid is less than or equal to the first preset weight value, it indicates that the patient's hemodialysis treatment is in a normal state. The cumulative weight reduction of the replacement fluid in the first fluid bag is then calculated, where the cumulative weight reduction of the replacement fluid in the first fluid bag = actual weight of the first fluid bag - initial weight of the first fluid bag. The cumulative weight reduction of the replacement fluid in the first fluid bag represents the cumulative weight of the replacement fluid connected to the blood circuit. By viewing the cumulative weight reduction value displayed on the screen, the user can determine in real time whether the cumulative total amount of replacement fluid connected to the blood circuit is too high or too low, thus ensuring the safety of the replacement fluid connected to the blood circuit.

[0135] It should be noted that the first preset weight value can be set based on clinical experience and is related to the patient's clinical symptoms. For example, the first preset weight value is 3000g. When the actual total weight of the liquid minus the initial total weight of the liquid is greater than 3000g, it indicates that the patient's blood has lost too much substance during the hemodialysis treatment, and the sixth prompt message will be displayed on the screen.

[0136] In this embodiment, when a patient is undergoing hemodialysis treatment, the difference between the actual total weight of the liquid in the hemodialysis device and the initial total weight of the liquid in the hemodialysis device can be used to determine whether there is a malfunction in the hemodialysis treatment process, thus improving the liquid balance safety level of the hemodialysis device.

[0137] It should be noted that the weights of "initial weight of the second replenishment bag", "initial weight of the waste bag", "actual weight of the second replenishment bag", and "actual weight of the waste bag" include both the weight of the bag itself and the weight of the liquid inside the bag; however, "initial total weight of liquid" and "actual total weight of liquid" both represent the difference between the weights of the bags, and therefore this difference represents the difference between the weights of the liquid inside the bags.

[0138] Similarly, the weight changes referred to as "first weight decrease," "second weight decrease," and "first weight increase" are the differences in the weight of the liquid inside the bag.

[0139] However, both "first test weight" and "second test weight" refer to the weight of the liquid inside the bag, excluding the weight of the bag itself.

[0140] It should be noted that the sequence numbers of the above steps (such as S101, S102, etc.) are only used to refer to each step and do not mean that the steps in this embodiment will be executed in the order of the sequence numbers. The steps in this embodiment will be executed in the logical order of the technical solution.

[0141] This application also provides a computer-readable storage medium storing a computer program that, when executed by a processor, causes the processor to implement the fluid balance regulation method for any of the above-described hemodialysis devices. For detailed descriptions of related content, please refer to the relevant content of the above methods, which will not be repeated here.

[0142] The computer-readable storage medium can be an internal storage unit of the aforementioned hemodialysis device, such as a hard disk or memory. Alternatively, it can be an external storage device, such as an external hard disk, smart memory card, secure digital card, flash memory card, etc.

[0143] It should be understood that the terminology used in this application specification is for the purpose of describing particular embodiments only and is not intended to limit the application.

[0144] It should also be understood that the term “and / or” as used in this application specification and the appended claims means any combination of one or more of the associated listed items and all possible combinations, and includes such combinations.

[0145] The above description is merely a specific embodiment of this application, but the scope of protection of this application is not limited thereto. Any person skilled in the art can easily conceive of various equivalent modifications or substitutions within the technical scope disclosed in this application, and such modifications or substitutions should all be covered within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.

Claims

1. A hemodialysis device, characterized in that, The hemodialysis device includes: a first waste fluid pump, a first inlet pump, a second inlet pump, a first inlet line, a second inlet line, a first waste fluid line, a first replenishment bag, a second replenishment bag, a first waste fluid bag, a blood circuit, a blood pump, and a dialyzer. The blood circuit is located between the patient's artery and vein. The blood pump is located within the blood circuit. The blood input and output ends of the dialyzer are connected in series within the blood circuit. The first waste fluid line connects the waste fluid output end of the dialyzer to the waste fluid bag. The first inlet line connects the blood circuit to the first replenishment bag. The second inlet line connects the dialysate input end of the dialyzer to the second replenishment bag. The first waste pump is located in the first waste line, the first inlet pump is located in the first inlet line, and the second inlet pump is located in the second inlet line. The first replenishment bag stores replacement fluid, and the second replenishment bag stores dialysate. The hemodialysis device further includes a memory and a processor. The memory stores a computer program, and the processor executes the computer program to implement the following fluid balance regulation method for the hemodialysis device: Based on the first theoretical flow rate received from the user, the rotation speed of the blood pump is adjusted to make the blood flow rate in the blood circuit equal to the first theoretical flow rate. The rotational speeds of the first inlet pump, the second inlet pump, and the first waste pump are respectively adjusted by feedback to make the displacement fluid flow rate of the first inlet pipeline equal to the first inlet flow rate, the dialysate flow rate of the second inlet pipeline equal to the second inlet flow rate, and the waste liquid flow rate of the first waste liquid pipeline equal to the first waste liquid flow rate, wherein the first inlet flow rate, the second inlet flow rate, and the first waste liquid flow rate are all obtained based on the first theoretical flow rate; When the flow rate of the replacement fluid in the first inlet line is equal to the first inlet flow rate, the flow rate of the dialysate in the second inlet line is equal to the second inlet flow rate, and the flow rate of the waste liquid in the first waste liquid line is equal to the first waste liquid flow rate, the first weight reduction value of the replacement fluid in the first replenishment bag, the second weight reduction value of the dialysate in the second replenishment bag, and the first weight increase value of the waste liquid in the waste liquid bag are obtained respectively. Based on whether the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance conditions, it is determined whether to adjust the speed of the first waste liquid pump according to feedback.

2. The hemodialysis device according to claim 1, characterized in that, The processor is used to execute the computer program and, when executing the computer program, to implement the following method for regulating the fluid balance of a hemodialysis device: When the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the fluid balance condition, the rotation speed of the first waste liquid pump is adjusted by feedback, wherein the fluid balance condition includes: |first weight reduction value + second weight reduction value - first weight increase value| < first preset value.

3. The hemodialysis device according to claim 2, characterized in that, The processor is used to execute the computer program and, when executing the computer program, to implement the following method for regulating the fluid balance of a hemodialysis device: When the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the first balance condition, but meet the second balance condition, the rotational speed of the first waste liquid pump is adjusted based on feedback. The first balance condition includes: |first weight reduction + second weight reduction - first weight increase| > second preset value; the second balance condition includes: |first weight reduction + second weight reduction - first weight increase| > first preset value; the second preset value is greater than the first preset value. When the first weight reduction value, the second weight reduction value, and the first weight increase value satisfy the first balance condition, the blood pump, the first waste liquid pump, the first inlet pump, and the second inlet pump are all stopped, and a first prompt signal is issued.

4. The hemodialysis device according to claim 2, characterized in that, The processor is used to execute the computer program and, when executing the computer program, to implement the following method for regulating the fluid balance of a hemodialysis device: When the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the first condition, the speed of the first waste liquid pump is increased. The first condition includes: first weight reduction value + second weight reduction value - first weight increase value < first preset value. When the first weight reduction value, the second weight reduction value, and the first weight increase value do not meet the second condition, the speed of the first waste liquid pump is reduced. The second condition includes: first weight increase value - first weight reduction value - second weight reduction value < first preset value.

5. The hemodialysis device according to claim 1, characterized in that, The processor is used to execute the computer program and, when executing the computer program, to implement the following method for regulating the fluid balance of a hemodialysis device: The first detection weight of the remaining liquid in the first replenishment bag and the second detection weight of the remaining liquid in the second replenishment bag are obtained respectively. A second alert signal is issued when the first detected weight is less than or equal to the preset safe weight, and / or when the second detected weight is less than or equal to the preset safe weight.

6. The hemodialysis device according to claim 2, characterized in that, The processor is used to execute the computer program and, when executing the computer program, to implement the following method for regulating the fluid balance of a hemodialysis device: When the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance condition, a first ratio between the first weight reduction value and the first weight increase value, and a second ratio between the second weight reduction value and the first weight increase value are determined respectively, and the first ratio and the second ratio are displayed on the display screen of the hemodialysis device.

7. The hemodialysis device according to claim 2, characterized in that, The hemodialysis device further includes: a first temperature sensor, a second temperature sensor, and a third temperature sensor; the first temperature sensor is disposed in the first inlet pipe, the second temperature sensor is disposed in the second inlet pipe, and the third temperature sensor is disposed in the first waste liquid pipe; The processor is used to execute the computer program and, when executing the computer program, to implement the following method for regulating the fluid balance of a hemodialysis device: When the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance condition, the first temperature sensor, the second temperature sensor, and the third temperature sensor are used to detect the replacement fluid temperature of the first inlet pipeline, the dialysate temperature of the second inlet pipeline, and the waste liquid temperature of the first waste liquid pipeline, respectively, to obtain the first detection temperature, the second detection temperature, and the third detection temperature. When the first detection temperature, the second detection temperature, and the third detection temperature do not meet the temperature balance condition, a fourth prompt message is issued. The temperature balance condition is: |(first detection temperature + second detection temperature) / 2 - third detection temperature| < first preset temperature.

8. The hemodialysis device according to claim 7, characterized in that, The hemodialysis device further includes: a fourth temperature sensor, the fourth temperature sensor being disposed in the blood circuit; the processor is used to execute the computer program and, when executing the computer program, to implement the following method for regulating the fluid balance of the hemodialysis device: The fourth temperature sensor is used to detect the blood temperature in the blood circuit to obtain the fourth detection temperature; The first preset temperature is determined based on the fourth detected temperature.

9. The hemodialysis device according to claim 2, characterized in that, The processor is used to execute the computer program and, when executing the computer program, to implement the following method for regulating the fluid balance of a hemodialysis device: The initial weight of the second replenishment bag and the initial weight of the waste bag are detected; Determine the initial total weight of the liquid in the hemodialysis device, wherein the initial total weight of the liquid is equal to the sum of the initial weight of the second replenishment bag and the initial weight of the waste bag; When the first weight reduction value, the second weight reduction value, and the first weight increase value meet the fluid balance condition, the actual weight of the second fluid replenishment bag and the actual weight of the waste fluid bag are detected. The actual total weight of the liquid in the hemodialysis device is determined, and the actual total weight of the liquid is equal to the sum of the actual weight of the second replenishment bag and the actual weight of the waste bag; When the weight difference between the actual total weight of the liquid and the initial total weight of the liquid is less than or equal to a first preset weight value, the cumulative weight reduction value of the replacement fluid in the first fluid bag is determined, and the cumulative weight reduction value of the replacement fluid is displayed on the display screen of the hemodialysis device. When the difference between the actual total weight of the liquid and the initial total weight of the liquid is greater than the first preset weight value, a sixth prompt message is displayed on the display screen.

10. A computer-readable storage medium, characterized in that, The computer-readable storage medium stores a computer program that, when executed by a processor, causes the processor to implement the fluid balance regulation method for a hemodialysis device as described in any one of claims 1-9.

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