Freeze-drying line isolator control method and system
Patent Information
- Application Number
- CN202311630993.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-11-30
- Publication Date
- 2026-10-27
- Estimated Expiration
- 2043-11-30
AI Technical Summary
[0002]隔离器产品线中,隔离器布局模式繁多,由于隔离器设备特殊性,隔离器布局模式需要根据设备产品工艺进行设计,且隔离器布局模式和腔体一一对应不能修改,客户后期想增加和变更布局模式时,不同布局模式需要根据机型配置、空调配置、厂房布局、工艺等重新编写程序,对程序和验证改动十分巨大
本发明获取用户配方之后,根据用户配方中的产品布局和空调数量匹配对应的隔离器布局模式,然后根据用户配方中指定的工艺模式控制对应隔离器和空调运行。从而满足客户针对不同机型配置、空调配置、厂房布局、工艺模式等均可配置的要求。
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Figure CN117784724B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to pharmaceutical equipment control technology, and more particularly to a control method and system for a freeze dryer isolator. Background Technology
[0002] In the isolator product line, there are many isolator layout modes. Due to the special nature of isolator equipment, the isolator layout mode needs to be designed according to the equipment product process. Moreover, the isolator layout mode and the cavity are one-to-one and cannot be modified. When customers want to add or change the layout mode later, different layout modes require rewriting the program according to the model configuration, air conditioning configuration, factory layout, process, etc., which makes huge changes to the program and verification. Summary of the Invention
[0003] The technical problem to be solved by the present invention is as follows: In view of the technical problems existing in the prior art, the present invention provides a control method and system for isolators in freeze-drying lines, which sets common layout patterns in a program and configures them accordingly by obtaining user formulas, so as to flexibly meet the different requirements of customers for isolator layout patterns.
[0004] To solve the above-mentioned technical problems, the technical solution proposed by this invention is as follows: A method for controlling a freeze dryer isolator includes the following steps: User recipes are obtained through a user recipe interface, which includes buttons for creating, saving, retrieving, downloading, deactivating, and activating. The corresponding isolator layout is obtained by matching the product layout in the user's formula. The isolator layout includes any one of the L-shaped layout, the straight layout, and the T-shaped layout. The air conditioning configuration of the isolator is based on the number of air conditioners specified in the user's formula, where the number of air conditioners includes one to three air conditioners. Each isolator and air conditioner is controlled to operate in a specified state according to the process mode in the user's formula. The process mode includes any one of the water injection mode, inlet mode, and outlet mode.
[0005] Furthermore, according to the process mode in the user's formula, each isolator and air conditioner is controlled to operate in a specified state, including: When the process mode in the user's formula is water needle mode, the first designated air conditioner and the corresponding isolator are started to form a water needle line. The first designated air conditioner specifically refers to the air conditioner corresponding to all isolators in the water needle line. After the material transfer of the water needle line is completed, stop the operation of the first designated air conditioner and the corresponding isolator.
[0006] Furthermore, according to the process mode in the user's formula, each isolator and air conditioner is controlled to operate in a specified state, including: When the process mode in the user's formula is the in-box mode, start the second designated air conditioner and the corresponding isolator; After the feeding is completed, if water needle line operation is not required during freeze drying, the operation of the second designated air conditioner and its corresponding isolator is stopped. If water needle line operation is required during freeze drying, the operation of the third designated air conditioner and its corresponding isolator is maintained, and the operation of the remaining air conditioners and their corresponding isolators in the second designated air conditioner is stopped. The second designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze drying chamber, as well as the air conditioners corresponding to all isolators in the freeze drying line before the isolator connected to the freeze drying chamber. The third designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze drying chamber.
[0007] Furthermore, according to the process mode in the user's formula, each isolator and air conditioner is controlled to operate in a specified state, including: When the process mode in the user's formula is the box discharge mode, if the water needle line does not need to be run at the same time, the fourth designated air conditioner and the corresponding isolator will be started when discharging. If the water needle line needs to be run at the same time, the third designated air conditioner and the corresponding isolator will be maintained. When discharging, the remaining air conditioners in the fourth designated air conditioner and the corresponding isolators will be started. The fourth designated air conditioner is specifically the air conditioner corresponding to the isolator connected to the freeze-drying box, as well as the air conditioners corresponding to all isolators after the isolator connected to the freeze-drying box in the freeze-drying line. The third designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze-drying box. After the material discharge is completed, stop the operation of the third designated air conditioner and the corresponding isolator.
[0008] Furthermore, when matching the product layout in the user's formula to obtain the corresponding isolator layout, it includes: if the product layout is a straight layout, the corresponding isolator layout is a straight layout, including a bottle handling area isolator, a filling area isolator, a first inlet isolator, a second inlet isolator, a capping isolator, and an external washing isolator arranged sequentially in the vertical direction, wherein the first inlet isolator is connected to the freeze-drying chamber.
[0009] Furthermore, when configuring the air conditioning system for the isolator according to the number of air conditioners specified in the user's formula, it includes: If the number of air conditioners is one, the air conditioner refers to the air conditioner corresponding to all isolators; If there are two air conditioners, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator, the filling area isolator, and the first inlet isolator, and the second air conditioner is the air conditioner corresponding to the second inlet isolator, the capping isolator, and the external washing isolator; or, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator and the filling area isolator, and the second air conditioner is the air conditioner corresponding to the first inlet isolator, the second inlet isolator, the capping isolator, and the external washing isolator. If there are three air conditioners, the third air conditioner corresponds to the bottle handling area isolator and the filling area isolator, the fourth air conditioner corresponds to the first inlet isolator, and the fifth air conditioner corresponds to the second inlet isolator, the capping isolator, and the external washing isolator.
[0010] Furthermore, when matching the corresponding isolator layout based on the product layout in the user's formula, this includes: If the product layout is an L-shaped layout, the corresponding isolator layout is also an L-shaped layout, including a bottle handling area isolator, a filling area isolator, a first inlet isolator, and a second inlet isolator arranged in sequence along the vertical direction, and a third inlet isolator, a capping isolator, and an external washing isolator arranged in sequence along the horizontal direction. The second inlet isolator and the third inlet isolator are connected to form an L-shape, and the first inlet isolator is connected to the freeze-drying chamber.
[0011] Furthermore, when configuring the air conditioning system for the isolator according to the number of air conditioners specified in the user's formula, it includes: If the number of air conditioners is one, the air conditioner refers to the air conditioner corresponding to all isolators; If there are two air conditioners, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator, the filling area isolator, and the first inlet isolator, and the second air conditioner is the air conditioner corresponding to the second inlet isolator, the third inlet isolator, the capping isolator, and the external washing isolator; or, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator and the filling area isolator, and the second air conditioner is the air conditioner corresponding to the first inlet isolator, the second inlet isolator, the third inlet isolator, the capping isolator, and the external washing isolator. If there are three air conditioners, the third air conditioner corresponds to the bottle handling area isolator and the filling area isolator, the fourth air conditioner corresponds to the first inlet isolator and the second inlet isolator, and the fifth air conditioner corresponds to the third inlet isolator, the capping isolator, and the external washing isolator.
[0012] Furthermore, when matching the corresponding isolator layout based on the product layout in the user's formula, this includes: If the product layout is a T-shaped layout, the corresponding isolator layout is also a T-shaped layout, including a bottle handling area isolator, a filling area isolator, a first inlet isolator, and a second inlet isolator arranged in sequence along the vertical direction, and a third inlet isolator, a capping isolator, and an external washing isolator arranged in sequence along the horizontal direction. The third inlet isolator is connected to the first inlet isolator and the second inlet isolator respectively to form a T-shape, and the second inlet isolator is connected to the freeze-drying chamber.
[0013] Furthermore, when configuring the air conditioning system for the isolator according to the number of air conditioners specified in the user's formula, it includes: If the number of air conditioners is one, the air conditioner refers to the air conditioner corresponding to all isolators; If there are two air conditioners, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator, filling area isolator, inlet isolator 1, and inlet isolator 2, and the second air conditioner is the air conditioner corresponding to the inlet isolator 3, capping isolator, and external washing isolator; or, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator, filling area isolator, inlet isolator 1, inlet isolator 3, capping isolator, and external washing isolator, and the second air conditioner is the air conditioner corresponding to the inlet isolator 2. If there are three air conditioners, the third air conditioner corresponds to the bottle handling area isolator, the filling area isolator, and the first inlet isolator; the fourth air conditioner corresponds to the second inlet isolator; and the fifth air conditioner corresponds to the third inlet isolator, the capping isolator, and the external washing isolator.
[0014] This invention also proposes a freeze-drying line isolator control system, including an isolator layout module, an isolator operation module, and an air conditioning configuration module, wherein: The isolator layout module is used to match the product layout in the user's formula to obtain the corresponding isolator layout, which includes any one of L-shaped layout, straight layout and T-shaped layout; The air conditioning configuration module is used to configure the air conditioning of the isolator according to the number of air conditioners in the user's formula, wherein the number of air conditioners includes one to three air conditioners; The isolator operation module is used to control each isolator and air conditioner to operate in a specified state according to the process mode in the user's recipe. The process mode includes any one of the water needle mode, inlet mode and outlet mode.
[0015] Compared with the prior art, the advantages of the present invention are as follows: After obtaining the user's formula, this invention matches a corresponding isolator layout pattern based on the product layout and number of air conditioners in the user's formula. Then, it controls the operation of the corresponding isolators and air conditioners according to the process mode specified in the user's formula. This satisfies the customer's requirement that different models, air conditioner configurations, plant layouts, and process modes can all be configured. Attached Figure Description
[0016] Figure 1 The diagram shows different air conditioners configured for the L-shaped layout of the isolator, where (a) represents a diagram with one air conditioner, (b) represents a diagram of the first case with two air conditioners, (c) represents a diagram of the second case with two air conditioners, and (d) represents a diagram with three air conditioners.
[0017] Figure 2 The diagram shows different air conditioners configured in a linear layout for isolators, where (a) represents a diagram with one air conditioner, (b) represents a diagram of the first case with two air conditioners, (c) represents a diagram of the second case with two air conditioners, and (d) represents a diagram with three air conditioners.
[0018] Figure 3 The diagrams show different configurations of air conditioners for the T-shaped layout of the isolator, where (a) represents a diagram with one air conditioner, (b) represents a diagram of the first case with two air conditioners, (c) represents a diagram of the second case with two air conditioners, and (d) represents a diagram of a diagram with three air conditioners.
[0019] Figure 4 This is a flowchart of a method according to an embodiment of the present invention.
[0020] Figure 5 This is a schematic diagram of controlling the isolator and air conditioner under different process modes of an L-shaped layout isolator configured with an air conditioner in an embodiment of the present invention, wherein (a) is water needle mode, (b) is inlet mode, and (c) is outlet mode.
[0021] Figure 6 This is a schematic diagram of the control of the isolator and air conditioner under different process modes in the first case of the L-shaped layout of the isolator in an embodiment of the present invention, where (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0022] Figure 7 This is a schematic diagram of the control of the isolator and air conditioner under different process modes in the second case of the L-shaped layout of the isolator in the embodiment of the present invention, where (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0023] Figure 8 This is a schematic diagram of the control of the isolator and air conditioners under different process modes of the L-shaped layout configuration of the isolator in an embodiment of the present invention, wherein (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0024] Figure 9 This is a schematic diagram of the isolator and air conditioner controlled under different process modes in the isolator with a linear layout in an embodiment of the present invention, wherein (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0025] Figure 10 This is a schematic diagram of the control of the isolator and air conditioner under different process modes in the first case of the isolator with a straight layout and two air conditioners in an embodiment of the present invention, wherein (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0026] Figure 11 This is a schematic diagram of the control of the isolator and air conditioner under different process modes in the second case of the isolator with two air conditioners configured in a straight line in the embodiment of the present invention, wherein (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0027] Figure 12 This is a schematic diagram of the isolator and air conditioners controlled under different process modes with three air conditioners configured in a straight line layout in an embodiment of the present invention. (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0028] Figure 13 This is a schematic diagram of the control of the isolator and the air conditioner under different process modes of the isolator T-shaped layout configured with an air conditioner in an embodiment of the present invention, wherein (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0029] Figure 14 This is a schematic diagram of the control of the isolator and air conditioner under different process modes in the first case of the isolator T-shaped layout with two air conditioners in an embodiment of the present invention, wherein (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0030] Figure 15 This is a schematic diagram of the control of the isolator and air conditioner under different process modes in the second case of the isolator T-shaped layout with two air conditioners in an embodiment of the present invention, where (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0031] Figure 16 This is a schematic diagram of the control of the isolator and air conditioners under different process modes of the T-shaped layout configuration of the isolator in an embodiment of the present invention, wherein (a) is the water needle mode, (b) is the inlet mode, and (c) is the outlet mode.
[0032] Figure 17 This is a schematic diagram of the custom configuration page of the user recipe interface in an embodiment of the present invention.
[0033] Legend: 101-Bottle handling area isolator, 102-Filling area isolator, 103-Inlet 1 isolator, 104-Inlet 2 isolator, 105-Inlet 3 isolator, 106-Capping isolator, 107-External washing isolator. Detailed Implementation
[0034] The present invention will be further described below with reference to the accompanying drawings and specific preferred embodiments, but this does not limit the scope of protection of the present invention.
[0035] Before introducing specific embodiments of the present invention, relevant concepts will be explained.
[0036] Isolator layout patterns: The isolator layout patterns of the freeze-drying line include L-shaped layout, straight layout and T-shaped layout.
[0037] like Figure 1As shown, the L-shaped layout of the isolator includes a bottle handling area isolator 101, a filling area isolator 102, an inlet isolator 103, and an inlet second isolator 104 arranged sequentially in the vertical direction, and also includes an inlet third isolator 105, a capping isolator 106, and an external washing isolator 107 arranged sequentially in the horizontal direction. The inlet second isolator 104 and the inlet third isolator 105 are connected to form an L-shape, and the inlet first isolator 103 is connected to the freeze-drying chamber.
[0038] When an L-shaped layout is configured with one air conditioner, such as Figure 1 As shown in (a), the air conditioning AHU-1 controls the bottle area isolator 101, the filling area isolator 102, the first inlet isolator 103, the second inlet isolator 104, the third inlet isolator 105, the capping isolator 106, and the external washing isolator 107.
[0039] When an L-shaped layout is configured with two air conditioners, it can be like... Figure 1 As shown in (b), the air conditioning AHU-1 controls the bottle handling area isolator 101, the filling area isolator 102, and the first-entry isolator 103; the air conditioning AHU-2 controls the second-entry isolator 104, the third-entry isolator 105, the capping isolator 106, and the external washing isolator 107, or as shown in (b). Figure 1 As shown in (c), the air conditioning AHU-1 controls the bottle handling area isolator 101 and the filling area isolator 102, and the air conditioning AHU-2 controls the first inlet isolator 103, the second inlet isolator 104, the third inlet isolator 105, the capping isolator 106 and the external washing isolator 107.
[0040] When three air conditioners are configured in an L-shaped layout, such as Figure 1 As shown in (d), the air conditioner AHU-1 controls the bottle handling area isolator 101 and the filling area isolator 102, the air conditioner AHU-2 controls the first-entry isolator 103 and the second-entry isolator 104, and the air conditioner AHU-3 controls the third-entry isolator 105, the capping isolator 106, and the external washing isolator 107.
[0041] like Figure 2 As shown, the linear layout of the isolator includes a bottle handling area isolator 101, a filling area isolator 102, an inlet isolator 103, an inlet second isolator 104, a capping isolator 106, and an outer washing isolator 107 arranged in sequence along the vertical direction. The inlet isolator 103 is connected to the freeze-drying chamber.
[0042] When a single air conditioner is installed in a linear layout, such as Figure 2 As shown in (a), the air conditioning AHU-1 controls the bottle area isolator 101, the filling area isolator 102, the first inlet isolator 103, the second inlet isolator 104, the capping isolator 106, and the external washing isolator 107.
[0043] When two air conditioners are configured in a linear layout, it is possible to... Figure 2As shown in (b), the air conditioning AHU-1 controls the bottle handling area isolator 101, the filling area isolator 102, and the inlet isolator 103; the air conditioning AHU-2 controls the inlet second isolator 104, the capping isolator 106, and the external washing isolator 107, or as shown in (b). Figure 2 As shown in (c), the air conditioning AHU-1 controls the bottle handling area isolator 101 and the filling area isolator 102, and the air conditioning AHU-2 controls the first inlet isolator 103, the second inlet isolator 104, the capping isolator 106 and the external washing isolator 107.
[0044] When three air conditioners are configured in a linear layout, such as Figure 2 As shown in (d), the air conditioner AHU-1 controls the bottle handling area isolator 101 and the filling area isolator 102, the air conditioner AHU-2 controls the first-stage isolator 103, and the air conditioner AHU-3 controls the second-stage isolator 104, the capping isolator 106, and the external washing isolator 107.
[0045] like Figure 3 As shown, the T-shaped layout of the isolator includes a bottle handling area isolator 101, a filling area isolator 102, an inlet isolator 103, and an inlet second isolator 104 arranged sequentially along the vertical direction, and also includes an inlet third isolator 105, a capping isolator 106, and an outer washing isolator 107 arranged sequentially along the horizontal direction. The inlet third isolator 105 is connected to the inlet first isolator 103 and the inlet second isolator 104 respectively to form a T-shape, and the inlet second isolator 104 is connected to the freeze-drying chamber.
[0046] When a T-shaped layout is configured with one air conditioner, such as Figure 3 As shown in (a), the air conditioning AHU-1 controls the bottle area isolator 101, the filling area isolator 102, the first inlet isolator 103, the second inlet isolator 104, the third inlet isolator 105, the capping isolator 106, and the external washing isolator 107.
[0047] When two air conditioners are configured in a T-shaped layout, it is possible to... Figure 3 As shown in (b), the air conditioning AHU-1 controls the bottle handling area isolator 101, the filling area isolator 102, the first inlet isolator 103, and the second inlet isolator 104; the air conditioning AHU-2 controls the third inlet isolator 105, the capping isolator 106, and the external washing isolator 107, or as shown in (b). Figure 3 As shown in (c), the air conditioner AHU-1 controls the bottle handling area isolator 101, the filling area isolator 102, the first inlet isolator 103, the third inlet isolator 105, the capping isolator 106, and the external washing isolator 107, and the air conditioner AHU-2 controls the second inlet isolator 104.
[0048] When three air conditioners are configured in a T-shaped layout, such as Figure 3As shown in (d), the air conditioner AHU-1 controls the bottle handling area isolator 101 and the filling area isolator 102, the air conditioner AHU-2 controls the first-entry isolator 103 and the second-entry isolator 104, and the air conditioner AHU-3 controls the third-entry isolator 105, the capping isolator 106, and the external washing isolator 107.
[0049] Example 1 As mentioned above, due to the numerous isolator layout modes in freeze-drying lines, the current system requires rewriting the program to configure the isolator layout each time, depending on the machine model, air conditioning configuration, plant layout, and process. Furthermore, adding or changing modes later on necessitates significant modifications to the program and verification. To address these issues, this embodiment proposes a freeze-drying line isolator control method that matches a pre-configured layout mode to the user's formula to meet different requirements. Figure 4 As shown, it includes the following steps: S1) Obtain user recipes through the user recipe interface, which includes buttons for creating, saving, retrieving, downloading, deactivating, and activating. S2) Match the product layout in the user's formula to obtain the corresponding isolator layout, wherein the isolator layout includes any one of L-shaped layout, straight layout and T-shaped layout; S3) Configure the air conditioning in the isolator according to the number of air conditioners in the user's formula, wherein the number of air conditioners includes one to three air conditioners; S4) Control each isolator and air conditioner to operate in a specified state according to the process mode in the user's formula. The process mode includes any one of water needle mode, inlet mode and outlet mode.
[0050] This embodiment, through the above steps, controls the operation of different isolators and air conditioners according to product layout, process mode, and number of air conditioners, increasing the configuration options available to customers and improving the flexibility of isolator control. Each step is explained in detail below.
[0051] The button functions of the user recipe interface in this embodiment are described in detail below: Create: Create a new recipe (pattern scheme) that does not exist before the batch is launched; Save: Save the newly created recipe (pattern scheme) to the database; Retrieve: By selecting the recipe name and version number, retrieve the specific data of the previous version of the recipe (mode scheme) from the database for viewing; Download: Select the required recipe (mode scheme) by choosing the recipe name and version number and download it to the PLC program. The PLC program will execute according to the downloaded recipe (mode scheme). Deactivated: Changes the recipe status to deactivated. Recipes in the deactivated state cannot be downloaded. Activate: Changes the recipe status to active. Recipes in an active state can be downloaded.
[0052] Therefore, in step S1, obtaining the user recipe through the user recipe interface specifically refers to the user recipe obtained by the PLC program after the user sequentially performs the operations of creating, saving, recalling, activating, and downloading.
[0053] In step S2 of this embodiment, when obtaining the corresponding isolator layout based on the product layout in the user's formula, the following steps are included: If the product layout is a linear layout, the corresponding isolator layout is also a linear layout; If the product layout is L-shaped, the corresponding isolator layout is also L-shaped. If the product layout is a T-shape, the corresponding isolator layout is also a T-shape.
[0054] In this embodiment, the isolator layouts are all pre-stored in the database. The specific structures of the linear, L-shaped, and T-shaped layouts have been detailed above and will not be repeated in this embodiment.
[0055] In step S3 of this embodiment, configuring the air conditioner for the isolator according to the number of air conditioners in the user's formula includes: If the number of air conditioners is one, according to the above content, this air conditioner is the air conditioner corresponding to all isolators; If there are two air conditioners, then according to the above, the different isolators in the matched isolator layout will be configured as isolators corresponding to two different air conditioners. For distinction, the two air conditioners will be referred to as the first air conditioner and the second air conditioner. The isolators corresponding to the first air conditioner and the second air conditioner, that is, the isolators controlled by air conditioner AHU-1 and air conditioner AHU-2 in the first and second cases of different isolator layouts for two air conditioners, have been described in detail above and will not be repeated in this implementation.
[0056] If there are three air conditioners, then according to the above, the different isolators in the matched isolator layout will be configured as isolators corresponding to the three different air conditioners. For distinction, the three air conditioners will be referred to as the third air conditioner, the fourth air conditioner, and the fifth air conditioner. The isolators corresponding to the third air conditioner, the fourth air conditioner, and the fifth air conditioner, i.e., the isolators controlled by air conditioner AHU-1, air conditioner AHU-2, and air conditioner AHU-3 in the case of three air conditioners configured in different isolator layouts have been described in detail above and will not be repeated in this implementation.
[0057] In step S4 of this embodiment, controlling each isolator and air conditioner to operate in a specified state according to the process mode in the user's recipe includes: When the process mode in the user's formula is water needle mode, start the first designated air conditioner and the corresponding isolator to form a water needle line; After the material transfer on the water needle line is completed, stop the operation of the first designated air conditioner and the corresponding isolator.
[0058] In this embodiment, the isolator activated in water needle mode is specifically the isolator on the water needle line, and the first designated air conditioning control is the air conditioner corresponding to the isolator on the water needle line. For example: When an L-shaped layout is configured with one air conditioner, such as Figure 5 As shown in (a), the air conditioner AHU-1 is started, which controls the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106 and external washing isolator 107 to start and form a water jet line; then the air conditioner AHU-1 is stopped, and all the aforementioned isolators are shut down. When two air conditioners are configured in an L-shaped layout, such as Figure 6 (a) and Figure 7 As shown in (a), start air conditioners AHU-1 and AHU-2 to control the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106 and external washing isolator 107 to start and form a water jet line; then stop air conditioners AHU-1 and AHU-2, and all the aforementioned isolators will stop. When three air conditioners are configured in an L-shaped layout, such as Figure 8 As shown in (a), start air conditioners AHU-1, AHU-2, and AHU-3 to control the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106, and external washing isolator 107 to start and form a water jet line; then stop air conditioners AHU-1, AHU-2, and AHU-3, and all the aforementioned isolators will stop. When a single air conditioner is installed in a linear layout, such as Figure 9 As shown in (a), the air conditioner AHU-1 is started, which controls the bottle handling area isolator 101, filling area isolator 102, first inlet isolator 103, second inlet isolator 104, capping isolator 106 and external washing isolator 107 to start and form a water needle line; then the air conditioner AHU-1 is stopped, and all the aforementioned isolators are stopped. When two air conditioners are configured in a linear layout, such as Figure 10 (a) and Figure 11 As shown in (a), start air conditioners AHU-1 and AHU-2 to control the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, capping isolator 106 and external washing isolator 107 to start and form a water jet line; then stop air conditioners AHU-1 and AHU-2, and all the aforementioned isolators will stop. When three air conditioners are configured in a linear layout, such as Figure 12As shown in (a), start air conditioners AHU-1, AHU-2 and AHU-3, control the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, capping isolator 106 and external washing isolator 107 to start and form a water jet line; then stop air conditioners AHU-1, AHU-2 and AHU-3, and all the aforementioned isolators will stop. When a T-shaped layout is configured with one air conditioner, such as Figure 13 As shown in (a), the air conditioner AHU-1 is started, which controls the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106 and external washing isolator 107 to start and form a water jet line; then the air conditioner AHU-1 is stopped, and all the aforementioned isolators are shut down. When two air conditioners are configured in a T-shaped layout, the first scenario is as follows: Figure 14 As shown in (a), start air conditioners AHU-1 and AHU-2 to control the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106 and external washing isolator 107 to start and form a water jet line; then stop air conditioners AHU-1 and AHU-2, and all the aforementioned isolators will stop. When two air conditioners are configured in a T-shaped layout, the second scenario is as follows: Figure 15 As shown in (a), the air conditioner AHU-1 is started, which controls the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet 3 isolator 105, capping isolator 106 and external washing isolator 107 to start and form a water jet line; then the air conditioner AHU-1 is stopped, and all the aforementioned isolators are stopped. When three air conditioners are configured in a T-shaped layout, such as Figure 16 As shown in (a), start air conditioners AHU-1 and AHU-3 to control the bottle sorting area isolator 101, filling area isolator 102, inlet isolator 103, inlet 3 isolator 105, capping isolator 106 and external washing isolator 107 to start and form a water jet line; then stop air conditioners AHU-1 and AHU-3, and the bottle sorting area isolator 101, filling area isolator 102, inlet isolator 103, inlet 2 isolator 104, inlet 3 isolator 105, capping isolator 106 and external washing isolator 107 to stop.
[0059] In step S4 of this embodiment, controlling each isolator and air conditioner to operate in a specified state according to the process mode in the user's recipe further includes: When the process mode in the user's formula is the in-box mode, start the second designated air conditioner and the corresponding isolator; After the feeding is completed, if water needle line operation is not required during freeze drying, the control stops the operation of the second designated air conditioner and the corresponding isolator. If water needle line operation is required during freeze drying, the control maintains the operation of the third designated air conditioner and the corresponding isolator, and stops the operation of the remaining air conditioners and corresponding isolators in the second designated air conditioner.
[0060] In this embodiment, the second designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze-drying chamber in the freeze-drying line and all isolators preceding it, and the third designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze-drying chamber. For example: When an L-shaped layout is configured with one air conditioner, such as Figure 5 As shown in (b), in the box feeding mode, the air conditioner AHU-1 is started, controlling the bottle feeding area isolator 101, filling area isolator 102, first feeding isolator 103, second feeding isolator 104, third feeding isolator 105, capping isolator 106 and external washing isolator 107 to start; after the feeding is completed, if it is necessary to run the water injection line at the same time as freeze drying, the air conditioner AHU-1 is maintained, and all the aforementioned isolators are kept running; When two air conditioners are configured in an L-shaped layout, the first scenario is as follows: Figure 6 (b) shows that in the box feeding mode, the air conditioner AHU-1 is started, which controls the bottle feeding area isolator 101, the filling area isolator 102, and the feeding isolator 103 to start. After feeding is completed, if it is not necessary to run the water injection line at the same time as freeze drying, the air conditioner AHU-1 is stopped and the aforementioned isolators stop running. If it is necessary to run the water injection line at the same time as freeze drying, the air conditioner AHU-1 is maintained and the aforementioned isolators are maintained. When two air conditioners are configured in an L-shaped layout, the second scenario is as follows: Figure 7 (b) shows that in the box-feeding mode, air conditioners AHU-1 and AHU-2 are started to control the bottle feeding area isolator 101, filling area isolator 102, first feed isolator 103, second feed isolator 104, third feed isolator 105, capping isolator 106, and external washing isolator 107 to start. After feeding is completed, if water injection line operation is required during freeze-drying, air conditioner AHU-1 is stopped while air conditioner AHU-2 is maintained, so that bottle feeding area isolator 101 and filling area isolator 102 are stopped, while first feed isolator 103, second feed isolator 104, third feed isolator 105, capping isolator 106, and external washing isolator 107 continue to operate. If water injection line operation is not required during freeze-drying, air conditioners AHU-1 and AHU-2 are stopped, and all the aforementioned isolators are stopped. When three air conditioners are configured in an L-shaped layout, such as Figure 8(b) shows that in the box feeding mode, air conditioners AHU-1 and AHU-2 are started, controlling the bottle feeding area isolator 101, filling area isolator 102, feed isolator 103, and feed isolator 104 to start. After feeding is completed, if water injection line operation is required at the same time as freeze drying, air conditioner AHU-1 is stopped while air conditioner AHU-2 is maintained, so that bottle feeding area isolator 101 and filling area isolator 102 are stopped, while feed isolator 103 and feed isolator 104 continue to operate. If water injection line operation is not required at the same time as freeze drying, air conditioners AHU-1 and AHU-2 are stopped, and all the aforementioned isolators are stopped. When a single air conditioner is installed in a linear layout, such as Figure 9 As shown in (b), in the box-feeding mode, the air conditioner AHU-1 is started, controlling the bottle feeding area isolator 101, filling area isolator 102, first feeding isolator 103, second feeding isolator 104, capping isolator 106 and external washing isolator 107 to start; after feeding is completed, if it is necessary to run the water injection line at the same time as freeze drying, the air conditioner AHU-1 is maintained, and all the aforementioned isolators are kept running; When two air conditioners are configured in a linear layout, the first case is as follows: Figure 10 (b) shows that in the box feeding mode, the air conditioner AHU-1 is started, which controls the bottle feeding area isolator 101, the filling area isolator 102, and the feeding isolator 103 to start. After feeding is completed, if it is not necessary to run the water injection line at the same time as freeze drying, the air conditioner AHU-1 is stopped and the aforementioned isolators stop running. If it is necessary to run the water injection line at the same time as freeze drying, the air conditioner AHU-1 is maintained and the aforementioned isolators are maintained. When two air conditioners are configured in a linear layout, the second type of situation is as follows: Figure 11 (b) shows that in the box-feeding mode, air conditioners AHU-1 and AHU-2 are started to control the bottle-feeding area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, capping isolator 106, and external washing isolator 107 to start. After feeding is completed, if water injection line operation is required during freeze-drying, air conditioner AHU-1 is stopped while air conditioner AHU-2 is maintained, so that bottle-feeding area isolator 101 and filling area isolator 102 are stopped, while inlet isolator 103, inlet isolator 104, capping isolator 106, and external washing isolator 107 continue to operate. If water injection line operation is not required during freeze-drying, air conditioners AHU-1 and AHU-2 are stopped, and all the aforementioned isolators are stopped. When three air conditioners are configured in a linear layout, such as Figure 12(b) shows that in the box feeding mode, air conditioners AHU-1 and AHU-2 are started, controlling the bottle feeding area isolator 101, filling area isolator 102, and feed isolator 103 to start. After feeding is completed, if water injection line operation is required at the same time as freeze drying, air conditioner AHU-1 is stopped while air conditioner AHU-2 is maintained, so that bottle feeding area isolator 101 and filling area isolator 102 are stopped, and feed isolator 103 is kept running. If water injection line operation is not required at the same time as freeze drying, air conditioners AHU-1 and AHU-2 are stopped, and the aforementioned isolators are all stopped. When a T-shaped layout is configured with one air conditioner, such as Figure 13 As shown in (b), in the box feeding mode, the air conditioner AHU-1 is started, controlling the bottle feeding area isolator 101, filling area isolator 102, first feeding isolator 103, second feeding isolator 104, third feeding isolator 105, capping isolator 106 and external washing isolator 107 to start; after the feeding is completed, if it is necessary to run the water injection line at the same time as freeze drying, the air conditioner AHU-1 is maintained, and all the aforementioned isolators are kept running; When two air conditioners are configured in a T-shaped layout, the first scenario is as follows: Figure 14 (b) shows that in the box feeding mode, the air conditioning AHU-1 is started, which controls the bottle feeding area isolator 101, the filling area isolator 102, the first feed isolator 103, and the second feed isolator 104 to start. After feeding is completed, if it is not necessary to run the water injection line at the same time as freeze drying, the air conditioning AHU-1 is stopped and the aforementioned isolators stop running. If it is necessary to run the water injection line at the same time as freeze drying, the air conditioning AHU-1 is maintained and the aforementioned isolators are maintained running. When two air conditioners are configured in a T-shaped layout, the second scenario is as follows: Figure 15 (b) shows that in the box feeding mode, air conditioners AHU-1 and AHU-2 are started to control the bottle feeding area isolator 101, filling area isolator 102, feed isolator 103, and feed isolator 104 to start. After feeding is completed, if water injection line operation is required at the same time as freeze drying, air conditioner AHU-1 is stopped while air conditioner AHU-2 is maintained, so that bottle feeding area isolator 101, filling area isolator 102, and feed isolator 103 are stopped, while feed isolator 104 continues to run. If water injection line operation is not required at the same time as freeze drying, air conditioners AHU-1 and AHU-2 are stopped, and all the aforementioned isolators are stopped. When three air conditioners are configured in a T-shaped layout, such as Figure 16(b) shows that in the box feeding mode, air conditioners AHU-1 and AHU-2 are started to control the bottle feeding area isolator 101, filling area isolator 102, feed isolator 103, and feed isolator 104 to start. After feeding is completed, if water injection line operation is required at the same time as freeze drying, air conditioner AHU-1 is stopped while air conditioner AHU-2 is maintained, so that bottle feeding area isolator 101, filling area isolator 102, and feed isolator 103 are stopped, while feed isolator 104 is kept running. If water injection line operation is not required at the same time as freeze drying, air conditioners AHU-1 and AHU-2 are stopped, and all the aforementioned isolators are stopped.
[0061] In step S4 of this embodiment, controlling each isolator and air conditioner to operate in a specified state according to the process mode in the user's recipe further includes: When the process mode in the user's formula is the unpacking mode, if the water needle line does not need to be run at the same time, the fourth designated air conditioner and the corresponding isolator will be started when discharging. If the water needle line needs to be run at the same time, the third designated air conditioner and the corresponding isolator will be maintained. When discharging, the remaining air conditioners in the fourth designated air conditioner and the corresponding isolator will be started. After the material discharge is completed, stop the operation of the third designated air conditioner and the corresponding isolator.
[0062] In this embodiment, the fourth designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze-drying chamber in the freeze-drying line and all subsequent isolators, while the third designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze-drying chamber. For example: When an L-shaped layout is configured with one air conditioner, such as Figure 5 (c) shows that in the unloading mode, if the water injection line does not need to be running while discharging, the air conditioner AHU-1 is activated during discharging, controlling the start of the first isolator 103, the second isolator 104, the third isolator 105, the capping isolator 106, and the external washing isolator 107; if the water injection line needs to be running while discharging, the air conditioner AHU-1 is maintained, controlling the bottle unloading area isolator 101, the filling area isolator 102, the first isolator 103, the second isolator 104, the third isolator 105, the capping isolator 106, and the external washing isolator 107 to continue operating; after discharging is completed, the air conditioner AHU-1 is stopped, and all the aforementioned isolators stop operating; When two air conditioners are configured in an L-shaped layout, the first scenario is as follows: Figure 6(c) shows that in the discharging mode, if the water injection line does not need to be running simultaneously with discharging, then air conditioners AHU-1 and AHU-2 are activated during discharging, controlling the bottle unloading area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106, and external washing isolator 107 to start. If the water injection line needs to be running simultaneously with discharging, then air conditioner AHU-1 is maintained, and air conditioner AHU-2 is activated during discharging, so that bottle unloading area isolator 101, filling area isolator 102, and inlet isolator 103 continue to run, and inlet isolator 104, capping isolator 106, and external washing isolator 107 are activated again when discharging. After discharging is completed, air conditioners AHU-1 and AHU-2 are stopped, and all the aforementioned isolators stop running. When two air conditioners are configured in an L-shaped layout, the second scenario is as follows: Figure 7 (c) shows that in the unloading mode, if the water injection line does not need to be running while discharging, the air conditioner AHU-2 is started during discharging, controlling the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106 and external washing isolator 107 to start; if the water injection line needs to be running while discharging, the air conditioner AHU-2 is maintained; after discharging is completed, the air conditioner AHU-2 is stopped, and all the aforementioned isolators stop running. When three air conditioners are configured in an L-shaped layout, such as Figure 8 (c) shows that in the unloading mode, if the water jet line does not need to be run while discharging, the air conditioners AHU-2 and AHU-3 are started when discharging, controlling the start of the first isolator 103, the second isolator 104, the third isolator 105, the capping isolator 106, and the external washing isolator 107. If the water jet line needs to be run while discharging, the air conditioner AHU-2 is maintained, and the air conditioner AHU-3 is started when discharging, so that the first isolator 103 and the second isolator 104 continue to run, and the third isolator 105, the capping isolator 106, and the external washing isolator 107 are started again when discharging. After discharging is completed, the air conditioners AHU-2 and AHU-3 are stopped, and all the aforementioned isolators stop running. When a single air conditioner is installed in a linear layout, such as Figure 9 (c) shows that in the unloading mode, if the water injection line does not need to be running while discharging, the air conditioner AHU-1 is activated during discharging, controlling the first inlet isolator 103, the second inlet isolator 104, the capping isolator 106, and the external washing isolator 107 to start; if the water injection line needs to be running while discharging, the air conditioner AHU-1 is maintained, so that the bottle handling area isolator 101, the filling area isolator 102, the first inlet isolator 103, the second inlet isolator 104, the capping isolator 106, and the external washing isolator 107 continue to operate; after discharging is completed, the air conditioner AHU-1 is stopped, and all the aforementioned isolators stop operating; When two air conditioners are configured in a linear layout, the first case is as follows: Figure 10 (c) shows that in the discharging mode, if the water injection line does not need to be running while discharging, the air conditioners AHU-1 and AHU-2 are activated during discharging to control the bottle unloading area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, capping isolator 106, and external washing isolator 107 to start. If the water injection line needs to be running while discharging, the air conditioner AHU-1 is maintained, and the air conditioner AHU-2 is activated during discharging, so that the bottle unloading area isolator 101, filling area isolator 102, and inlet isolator 103 continue to run, and the inlet isolator 104, capping isolator 106, and external washing isolator 107 are activated again when discharging. After discharging is completed, the air conditioners AHU-1 and AHU-2 are stopped, and all the aforementioned isolators stop running. When two air conditioners are configured in a linear layout, the second type of situation is as follows: Figure 11 (c) shows that in the unloading mode, if the water needle line does not need to be run while unloading, the air conditioner AHU-2 is started during unloading, controlling the start of the first isolator 103, the second isolator 104, the capping isolator 106 and the external washing isolator 107; if the water needle line needs to be run while unloading, the air conditioner AHU-2 is maintained, controlling the aforementioned isolators to continue running; after unloading is completed, the air conditioner AHU-2 is stopped, and all the aforementioned isolators stop running. When three air conditioners are configured in a linear layout, such as Figure 12 (c) shows that in the unloading mode, if the water jet line does not need to be running while discharging, the air conditioners AHU-2 and AHU-3 are started when discharging, controlling the start of the first isolator 103, the second isolator 104, the capping isolator 106, and the external washing isolator 107; if the water jet line needs to be running while discharging, the air conditioner AHU-2 is maintained, and the air conditioner AHU-3 is started when discharging, so that the first isolator 103 continues to run and the second isolator 104, the capping isolator 106, and the external washing isolator 107 are started again when discharging; after discharging is completed, the air conditioners AHU-2 and AHU-3 are stopped, and all the aforementioned isolators stop running; When a T-shaped layout is configured with one air conditioner, such as Figure 13 (c) shows that in the discharging mode, if the water injection line does not need to be run while discharging, the air conditioning AHU-1 is activated during discharging, controlling the bottle handling area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106 and external washing isolator 107 to start; if the water injection line needs to be run while discharging, the air conditioning AHU-1 is maintained, so that the aforementioned isolators continue to operate; after discharging is completed, the air conditioning AHU-1 is stopped, and the aforementioned isolators all stop operating. When two air conditioners are configured in a T-shaped layout, the first scenario is as follows: Figure 14(c) shows that in the discharging mode, if the water injection line does not need to be running simultaneously with discharging, then air conditioners AHU-1 and AHU-2 are activated during discharging, controlling the bottle unloading area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106, and external washing isolator 107 to start. If the water injection line needs to be running simultaneously with discharging, then air conditioner AHU-1 is maintained, and air conditioner AHU-2 is activated during discharging, so that bottle unloading area isolator 101, filling area isolator 102, inlet isolator 103, and inlet isolator 104 continue to run, and inlet isolator 105, capping isolator 106, and external washing isolator 107 are activated again when discharging. After discharging is completed, air conditioners AHU-1 and AHU-2 are stopped, and all the aforementioned isolators stop running. When two air conditioners are configured in a T-shaped layout, the second scenario is as follows: Figure 15 (c) shows that in the discharging mode, if the water injection line does not need to be running simultaneously with discharging, then air conditioners AHU-1 and AHU-2 are activated during discharging, controlling the bottle sorting area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 104, inlet isolator 105, capping isolator 106, and external washing isolator 107 to start. If the water injection line needs to be running simultaneously with discharging, then air conditioner AHU-2 is maintained, and air conditioner AHU-1 is activated during discharging, so that inlet isolator 104 continues to run and bottle sorting area isolator 101, filling area isolator 102, inlet isolator 103, inlet isolator 105, capping isolator 106, and external washing isolator 107 are activated again during discharging. After discharging is completed, air conditioners AHU-1 and AHU-2 are stopped, and all the aforementioned isolators stop running. When three air conditioners are configured in a T-shaped layout, such as Figure 16 (c) shows that in the unloading mode, if the water injection line does not need to be running while discharging, the air conditioners AHU-2 and AHU-3 are started when discharging, controlling the second inlet isolator 104, the third inlet isolator 105, the capping isolator 106, and the external washing isolator 107 to start; if the water injection line needs to be running while discharging, the air conditioner AHU-2 is maintained, and the air conditioner AHU-3 is started when discharging, so that the second inlet isolator 104 continues to run and the third inlet isolator 105, the capping isolator 106, and the external washing isolator 107 are started again when discharging; after discharging is completed, the air conditioners AHU-2 and AHU-3 are stopped, and all the aforementioned isolators stop running.
[0063] Through step S4, the method of this embodiment can meet the requirements for water needle line operation during freeze drying. It can also automatically select whether to keep the isolator running before freeze drying based on the isolator layout and whether there is a separate air conditioner before the isolator of the freeze drying chamber. It can flexibly and reliably control the isolator according to the layout mode configured by the user, and meet the different requirements of all customers for the isolator layout mode.
[0064] Example 2 This embodiment is basically the same as Embodiment 1, except that, considering that Embodiment 1 only matches user recipes to commonly used isolator layout patterns, which may still not meet the needs of certain specific layouts, this embodiment makes further improvements by adding a user-defined page to the user recipe interface, such as... Figure 17 As shown, the user can modify the specified operating status of the isolators and air conditioners based on the isolator layout pattern obtained by matching the user recipe. Correspondingly, in step S4, before controlling each isolator and air conditioner to operate in the specified state according to the process mode in the user recipe, it also includes: waiting for and obtaining the operating status reassigned by the user to the target isolator and / or air conditioner.
[0065] For example, based on the product layout and number of air conditioners in the user's formula, an L-shaped layout with three air conditioners is matched. The process mode in the user's formula is water injection mode. By default, to control each isolator and air conditioner to operate in the specified state according to the process mode in the user's formula, air conditioners AHU-1, AHU-2, and AHU-3 need to be started to control the bottle handling area isolator 101, filling area isolator 102, first-stage isolator 103, second-stage isolator 104, third-stage isolator 105, capping isolator 106, and the outer... When the wash isolator 107 is started and forms a water jet line, if the user changes the operating status of the external wash isolator 107 controlled by the air conditioner AHU-3 to "stop" in the user-customized page of the user formula interface according to the actual situation, then in the actual water jet line, the air conditioners AHU-1, AHU-2 and AHU-3 are started, controlling the bottle handling area isolator 101, filling area isolator 102, first-stage isolator 103, second-stage isolator 104, third-stage isolator 105 and capping isolator 106 to start and the external wash isolator 107 to stop running.
[0066] Example 3 This embodiment proposes a freeze-drying line isolator control system, including an isolator layout module, an isolator operation module, and an air conditioning configuration module, wherein: The isolator layout module is used to match the product layout in the user's formula to obtain the corresponding isolator layout, which includes any one of L-shaped layout, straight layout and T-shaped layout; The air conditioning configuration module is used to configure the air conditioning of the isolator according to the number of air conditioners in the user's formula, wherein the number of air conditioners includes one to three air conditioners; The isolator operation module is used to control each isolator and air conditioner to operate in a specified state according to the process mode in the user's recipe. The process mode includes any one of the water needle mode, inlet mode and outlet mode.
[0067] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention in any way. Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the invention. Therefore, any simple modifications, equivalent changes, and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention should fall within the protection scope of the present invention.
Claims
1. A control method for an isolator in a freeze-drying line, characterized in that, Includes the following steps: User recipes are obtained through a user recipe interface, which includes buttons for creating, saving, retrieving, downloading, deactivating, and activating. The corresponding isolator layout is obtained by matching the product layout in the user's formula. The isolator layout includes any one of the L-shaped layout, the straight layout, and the T-shaped layout. The air conditioning configuration of the isolator is based on the number of air conditioners specified in the user's formula, where the number of air conditioners includes one to three air conditioners. Controlling each isolator and air conditioner to operate in a specified state according to the process mode in the user's formula, wherein the process mode includes any one of water injection mode, inlet mode, and outlet mode, and controlling each isolator and air conditioner to operate in a specified state according to the process mode in the user's formula includes: When the process mode in the user's formula is the in-box mode, start the second designated air conditioner and the corresponding isolator; After the feeding is completed, if water needle line operation is not required during freeze drying, the operation of the second designated air conditioner and its corresponding isolator is stopped. If water needle line operation is required during freeze drying, the operation of the third designated air conditioner and its corresponding isolator is maintained, and the operation of the remaining air conditioners and their corresponding isolators in the second designated air conditioner is stopped. The second designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze drying chamber, as well as the air conditioners corresponding to all isolators in the freeze drying line before the isolator connected to the freeze drying chamber. The third designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze drying chamber.
2. The freeze-drying line isolator control method according to claim 1, characterized in that, Control each isolator and air conditioner to operate in a specified state according to the process mode in the user's formula, including: When the process mode in the user's formula is water needle mode, the first designated air conditioner and the corresponding isolator are started to form a water needle line. The first designated air conditioner specifically refers to the air conditioner corresponding to all isolators in the water needle line. After the material transfer of the water needle line is completed, stop the operation of the first designated air conditioner and the corresponding isolator.
3. The freeze-drying line isolator control method according to claim 1, characterized in that, Control each isolator and air conditioner to operate in a specified state according to the process mode in the user's formula, including: When the process mode in the user's formula is the box discharge mode, if the water needle line does not need to be run at the same time, the fourth designated air conditioner and the corresponding isolator will be started when discharging. If the water needle line needs to be run at the same time, the third designated air conditioner and the corresponding isolator will be maintained. When discharging, the remaining air conditioners in the fourth designated air conditioner and the corresponding isolators will be started. The fourth designated air conditioner is specifically the air conditioner corresponding to the isolator connected to the freeze-drying box, as well as the air conditioners corresponding to all isolators after the isolator connected to the freeze-drying box in the freeze-drying line. The third designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze-drying box. After the material discharge is completed, stop the operation of the third designated air conditioner and the corresponding isolator.
4. The freeze-drying line isolator control method according to claim 1, characterized in that, When matching the corresponding isolator layout based on the product layout in the user's formula, it includes: If the product layout is an L-shaped layout, the corresponding isolator layout is also an L-shaped layout, including a bottle handling area isolator, a filling area isolator, a first inlet isolator, and a second inlet isolator arranged in sequence along the vertical direction, and a third inlet isolator, a capping isolator, and an external washing isolator arranged in sequence along the horizontal direction. The second inlet isolator and the third inlet isolator are connected to form an L-shape, and the first inlet isolator is connected to the freeze-drying chamber.
5. The freeze-drying line isolator control method according to claim 4, characterized in that, When configuring the air conditioning system for the isolator according to the number of air conditioners specified in the user's formula, the following should be included: If the number of air conditioners is one, the air conditioner refers to the air conditioner corresponding to all isolators; If there are two air conditioners, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator, the filling area isolator, and the first inlet isolator, and the second air conditioner is the air conditioner corresponding to the second inlet isolator, the third inlet isolator, the capping isolator, and the external washing isolator; or, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator and the filling area isolator, and the second air conditioner is the air conditioner corresponding to the first inlet isolator, the second inlet isolator, the third inlet isolator, the capping isolator, and the external washing isolator. If there are three air conditioners, the third air conditioner corresponds to the bottle handling area isolator and the filling area isolator, the fourth air conditioner corresponds to the first inlet isolator and the second inlet isolator, and the fifth air conditioner corresponds to the third inlet isolator, the capping isolator, and the external washing isolator.
6. The freeze-drying line isolator control method according to claim 1, characterized in that, When the corresponding isolator layout is obtained by matching the product layout in the user's formula, it includes: if the product layout is a straight layout, the corresponding isolator layout is a straight layout, including a bottle handling area isolator, a filling area isolator, a first inlet isolator, a second inlet isolator, a capping isolator and an external washing isolator arranged in sequence along the vertical direction, wherein the first inlet isolator is connected to the freeze-drying chamber; When configuring the air conditioning system for the isolator according to the number of air conditioners specified in the user's formula, the following should be included: If the number of air conditioners is one, the air conditioner refers to the air conditioner corresponding to all isolators; If there are two air conditioners, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator, the filling area isolator, and the first inlet isolator, and the second air conditioner is the air conditioner corresponding to the second inlet isolator, the capping isolator, and the external washing isolator; or, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator and the filling area isolator, and the second air conditioner is the air conditioner corresponding to the first inlet isolator, the second inlet isolator, the capping isolator, and the external washing isolator. If there are three air conditioners, the third air conditioner corresponds to the bottle handling area isolator and the filling area isolator, the fourth air conditioner corresponds to the first inlet isolator, and the fifth air conditioner corresponds to the second inlet isolator, the capping isolator, and the external washing isolator.
7. The freeze-drying line isolator control method according to claim 1, characterized in that, When matching the corresponding isolator layout based on the product layout in the user's formula, it includes: If the product layout is a T-shaped layout, the corresponding isolator layout is also a T-shaped layout, including a bottle handling area isolator, a filling area isolator, a first inlet isolator, and a second inlet isolator arranged in sequence along the vertical direction, and a third inlet isolator, a capping isolator, and an external washing isolator arranged in sequence along the horizontal direction. The third inlet isolator is connected to the first inlet isolator and the second inlet isolator respectively to form a T-shape, and the second inlet isolator is connected to the freeze-drying chamber.
8. The freeze-drying line isolator control method according to claim 7, characterized in that, When configuring the air conditioning system for the isolator according to the number of air conditioners specified in the user's formula, the following should be included: If the number of air conditioners is one, the air conditioner refers to the air conditioner corresponding to all isolators; If there are two air conditioners, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator, filling area isolator, inlet isolator 1, and inlet isolator 2, and the second air conditioner is the air conditioner corresponding to the inlet isolator 3, capping isolator, and external washing isolator; or, the first air conditioner is the air conditioner corresponding to the bottle sorting area isolator, filling area isolator, inlet isolator 1, inlet isolator 3, capping isolator, and external washing isolator, and the second air conditioner is the air conditioner corresponding to the inlet isolator 2. If there are three air conditioners, the third air conditioner corresponds to the bottle handling area isolator, the filling area isolator, and the first inlet isolator; the fourth air conditioner corresponds to the second inlet isolator; and the fifth air conditioner corresponds to the third inlet isolator, the capping isolator, and the external washing isolator.
9. A freeze-drying line isolator control system, characterized in that, This includes an isolator layout module, an isolator operation module, and an air conditioning configuration module, among which: The isolator layout module is used to match the product layout in the user's formula to obtain the corresponding isolator layout, which includes any one of L-shaped layout, straight layout and T-shaped layout; The air conditioning configuration module is used to configure the air conditioning of the isolator according to the number of air conditioners in the user's formula, wherein the number of air conditioners includes one to three air conditioners; The isolator operation module is used to control each isolator and air conditioner to operate in a specified state according to the process mode in the user's recipe. The process mode includes any one of water injection mode, inlet mode, and outlet mode. Controlling each isolator and air conditioner to operate in a specified state according to the process mode in the user's recipe includes: When the process mode in the user's formula is the in-box mode, start the second designated air conditioner and the corresponding isolator; After the feeding is completed, if water needle line operation is not required during freeze drying, the operation of the second designated air conditioner and its corresponding isolator is stopped. If water needle line operation is required during freeze drying, the operation of the third designated air conditioner and its corresponding isolator is maintained, and the operation of the remaining air conditioners and their corresponding isolators in the second designated air conditioner is stopped. The second designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze drying chamber, as well as the air conditioners corresponding to all isolators in the freeze drying line before the isolator connected to the freeze drying chamber. The third designated air conditioner specifically refers to the air conditioner corresponding to the isolator connected to the freeze drying chamber.
Citation Information
Patent Citations
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