A trifluorophenylpyrimidine-containing formulation and use thereof

Abstract

The application provides a triflumezopyrim-containing preparation and application thereof, and the preparation is a suspension agent, which contains the following ingredients in percentage by weight: 5-15% of triflumezopyrim, 2-8% of a dispersing agent, 2-8% of a wetting agent, 0.5-2% of a thickening agent, 2-6% of an antifreezing agent, 0.05-0.2% of a preservative, 0.1-0.5% of an antifoaming agent, 0.5-3% of a suspending agent, and deionized water to 100%; the dispersing agent contains Morwet D-425 and sodium lignosulphonate; and the wetting agent is one or both of Terwet 1004 and Morwet EFW. The prepared suspension agent can significantly improve the wetting and penetration performance of the pesticide, improve the contact between the diluent of the pesticide and the rice leaves, significantly improve the control effect of the pesticide, reduce the dosage of the pesticide, and slow down the generation of pest resistance.

Description

Technical Field

[0001] This invention belongs to the field of pesticide technology, specifically relating to a formulation containing trifluoropyrimidine and its application. Background Technology

[0002] Rice is a major food crop in my country, and rice planthoppers pose a serious threat to rice yields. Rice planthoppers belong to the order Hemiptera, family Planthopperidae. They damage rice and other crops by sucking sap from plants with their stylets. They are one of the most significant migratory pests of rice, characterized by long migration distances, large affected areas, devastating impacts upon landing, and sudden onset of disease, seriously affecting food security. Rice planthoppers include the brown planthopper, white-backed planthopper, and gray planthopper. In addition to causing severe damage to rice, they also transmit rice viral diseases such as rice black-streaked dwarf virus and southern rice black-streaked dwarf virus.

[0003] Many pesticides are used to control rice planthoppers in agricultural production. However, due to the long-term, excessive, and irrational use of chemical agents, rice planthoppers have developed varying degrees of resistance to several pesticides, including imidacloprid, pymetrozine, thiamethoxam, and acetamiprid. For example, imidacloprid is rarely used in production due to resistance issues; in most areas of Shanghai, Jiangsu, Zhejiang, Anhui, Jiangxi, Fujian, Guangdong, and Guangxi, brown planthopper populations have moderate to high levels of resistance to pymetrozine. Therefore, screening new pesticides and formulations for the control of rice planthoppers is imperative.

[0004] Trifluoropyrimidine is a novel pyrimidinone compound developed by DuPont, primarily used to control rice planthoppers and leafhoppers. Existing literature mainly focuses on synergistic effects of pesticides mixed with trifluoropyrimidine, screening out pesticide compositions with significant synergistic effects. However, research on trifluoropyrimidine formulations is limited; currently registered formulations only include 10% trifluoropyrimidine suspension concentrate and 20% trifluoropyrimidine water-dispersible granules. This invention primarily conducts a comparative study of trifluoropyrimidine suspension concentrates, screening out highly effective suspension concentrate formulations through field efficacy comparison trials, aiming to provide a new approach for controlling rice planthoppers. Summary of the Invention

[0005] To address the problems existing in the prior art, the present invention provides the following technical solution: A formulation containing trifluoropyrimidine, wherein the formulation is a suspension, comprising the following components in weight percentage: trifluoropyrimidine 5-15%, dispersant 2-8%, wetting agent 2-8%, thickener 0.5-2%, antifreeze agent 2-6%, preservative 0.05-0.2%, defoamer 0.1-0.5%, suspending agent 0.5-3%, and deionized water to make up to 100%; Preferably, the product contains the following components in weight percentage: 8-12% trifluoropyrimidine, 2-8% dispersant, 2-8% wetting agent, 0.5-2% thickener, 2-6% antifreeze, 0.05-0.2% preservative, 0.1-0.5% defoamer, 0.5-3% suspending agent, and deionized water to make up to 100%. Preferably, the product contains the following components in weight percentage: 10% trifluoropyrimidine, 2-8% dispersant, 2-8% wetting agent, 0.5-2% thickener, 2-6% antifreeze, 0.05-0.2% preservative, 0.1-0.5% defoamer, 0.5-3% suspending agent, and deionized water to make up to 100%. Preferably, the dispersant comprises Morwet D-425 and sodium lignin benzenesulfonate; the wetting agent is one or both of Terwet 1004 and Morwet EFW. More preferably, the mass ratio of Morwet D-425 to sodium lignin benzenesulfonate is 1:4 to 4:1; the wetting agent comprises Terwet 1004 and Morwet EFW; and the mass ratio of Terwet 1004 to Morwet EFW is 1:4 to 4:1.

[0006] The thickener in the suspending agent of this invention comprises magnesium aluminum silicate and xanthan gum; the mass ratio of magnesium aluminum silicate and xanthan gum is 1:5-5:1; the antifreeze is ethylene glycol; the preservative is sodium benzoate; the defoamer is dimethyl silicone oil; and the suspending agent is organobentonite.

[0007] Preferably, the product comprises the following components in weight percentage: 10% trifluorophenylpyrimidine, 2% Morwet D-425, 2% sodium lignosulfonate, 2% Terwet 1004, 2% Morwet EFW, 0.85% magnesium aluminum silicate, 0.35% xanthan gum, 4% ethylene glycol, 0.1% sodium benzoate, 0.25% dimethyl silicone oil, 1.5% organobentonite, and deionized water to make up to 100%.

[0008] Preferably, the product comprises the following components in weight percentage: 10% trifluorophenylpyrimidine, 2% Morwet D-425, 2% sodium lignosulfonate, 4% Morwet EFW, 0.85% magnesium aluminum silicate, 0.35% xanthan gum, 4% ethylene glycol, 0.1% sodium benzoate, 0.25% dimethyl silicone oil, 1.5% organobentonite, and deionized water to make up to 100%.

[0009] The aforementioned trifluorophenylpyrimidine formulation is used for the control of rice planthoppers; rice planthoppers include brown planthoppers, white-backed planthoppers, or gray planthoppers.

[0010] By adopting the above technical solution, the present invention has the following beneficial effects: The suspension formulations 5 and 9 prepared by this invention can significantly improve the wetting and penetration properties of the pesticide, enhance the contact between the pesticide dilution and rice leaves, thereby significantly improving the control effect of the pesticide, reducing the dosage of the pesticide, and slowing down the development of pesticide resistance in pests. Detailed Implementation

[0011] The present invention will be further explained below with reference to specific embodiments.

[0012] Example 1: Preparation of Trifluorophenylpyrimidine Suspension Experimental materials: Trifluorophenylpyrimidine, TERSPERSE2700, SP-2700, Morwet D-425, sodium lignobenzenesulfonate, Terwet 1004, Morwet EFW, sodium dodecylbenzenesulfonate, magnesium aluminum silicate, xanthan gum, sodium benzoate, dimethyl silicone oil, ethylene glycol, organobentonite, deionized water; Preparation method: Weigh the active ingredient and excipients according to the proportion, mix them with deionized water as the dispersion medium, add zirconia beads and perform wet grinding to reduce the average particle size of the suspension to less than 3μm. After separating the zirconia beads, the pesticide suspension is obtained.

[0013] Table 1. Composition of Suspension Formulations 1-5

[0014] Table 2. Composition of Suspension Formulations 6-10

[0015] Tests have shown that all of the above-mentioned suspension formulations are qualified products.

[0016] Example 2: Field efficacy test of trifluorophenylpyrimidine suspension against rice planthopper Experimental crop: Rice variety Fengtianyou 553; Test pests: Rice planthoppers (brown planthopper, white-backed planthopper) Test reagents: Formulation 1-10; Positive control: 10% trifluoropyrimidine suspension (PD20171740). Experimental Methods: The experiment consisted of 10 treatments, a positive control, and a water control. Each treatment was replicated four times, with a plot area of ​​60 m², arranged in a randomized block design. Protective rows were set up between plots and around the experimental field. A 45 cm high ridge was constructed between plots using specialized waterproofing boards to prevent cross-contamination. At the early tillering stage of the rice, a backpack electric sprayer was used with 45 L / mu of diluted water for uniform spraying. No rain occurred during the application period.

[0017] Data Survey and Statistics: A plate sampling method was used, with 10 parallel skip sampling points per plot, 2 rice clumps per point, for a total of 20 clumps. The initial insect population in each plot was surveyed before pesticide application, and the residual insect population was surveyed 7 days after application. The control efficacy of each pesticide treatment against rice planthoppers was calculated using the following formula: Insect population reduction rate (%) = (Insect population before application - Insect population after application) / Insect population before application × 100; Control effect (%) = (Pest population reduction rate in the treatment area - Pest population reduction rate in the control area) / (1 - Pest population reduction rate in the control area) × 100.

[0018] Results and Analysis: As shown in Table 3, compared with formulations 1-4, 6-8, 10 and the known 10% trifluoropyrimidine suspension, the 10% trifluoropyrimidine suspension prepared by formulations 5 and 9 can significantly improve its control effect on rice planthoppers. It is speculated that this is because the use of a suitable combination of dispersant and wetting agent in the suspension can significantly improve the wetting and penetration performance of the agent, increase the contact between the diluted agent and the rice leaves, thereby significantly improving the control effect of the agent, reducing the dosage of the agent, and slowing down the development of pesticide resistance in pests.

[0019] Table 3. Field control efficacy of trifluoropyrimidine suspension against rice planthoppers.

[0020] The experimental results were statistically analyzed using Duncan's new multiple range method. Different lowercase letters in the same column of the table indicate significant differences among the treatments (P<0.05). Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and are not intended to limit it.

Claims

1. A formulation containing trifluoropyrimidine, characterized in that, It contains the following ingredients by weight percentage: 10% trifluorophenylpyrimidine, 2% Morwet D-425, 2% sodium lignosulfonate, 2% Terwet 1004, 2% MorwetEFW, 0.85% magnesium aluminum silicate, 0.35% xanthan gum, 4% ethylene glycol, 0.1% sodium benzoate, 0.25% dimethyl silicone oil, 1.5% organobentonite, and deionized water to make up to 100%.

2. A formulation containing trifluorophenylpyrimidine, characterized in that, It contains the following ingredients by weight percentage: 10% trifluorophenylpyrimidine, 2% Morwet D-425, 2% sodium lignosulfonate, 4% Morwet EFW, 0.85% magnesium aluminum silicate, 0.35% xanthan gum, 4% ethylene glycol, 0.1% sodium benzoate, 0.25% dimethyl silicone oil, 1.5% organobentonite, and deionized water to make up to 100%.

3. The use of the trifluorophenylpyrimidine formulation according to any one of claims 1-2 for the control of rice planthoppers.

4. The use according to claim 3, characterized in that, Rice planthoppers include brown planthoppers, white-backed planthoppers, or gray planthoppers.

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