A tumor tissue sampling device

Abstract

The application relates to the field of medical devices, in particular to a tumor tissue sampling device which comprises a sampling shell, the inside of the sampling shell is sequentially provided with an air extraction mechanism, a buffer mechanism, a puncture mechanism and a suction sampling mechanism from top to bottom; the air extraction mechanism is connected to the upper part of the buffer mechanism, and the puncture mechanism is connected to the lower part of the buffer mechanism; the suction sampling mechanism is engaged with the left side of the puncture mechanism. The air extraction mechanism drives the piston to move in the piston barrel by rotating the crank handle, so that the pressure in the piston barrel changes, and then the gas enters the piston barrel; the buffer mechanism enters the gas buffer barrel through the air inlet one-way valve two after the gas compression spring B, and carries out static pressure; the puncture mechanism is driven by the gas to push the baffle one, and then compresses the spring C, the elastic force pushes the puncture needle to puncture; the suction sampling mechanism drives the baffle two to move upward to change the air pressure through the gear and rack engagement, and the tissue is sucked into the sampling barrel through the drainage pipe and stored. The device can realize the technical effects of pressure control puncture and drainage.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a tumor tissue sampling device. Background Technology

[0002] Hepatobiliary surgery primarily studies hepatocellular carcinoma, hepatobiliary stones, post-hepatitis cirrhosis, and acute liver failure caused by severe hepatitis, which are major diseases that seriously threaten the health of Chinese people. Combining the characteristics of hepatobiliary diseases in the Chinese population, China's hepatobiliary surgery department has developed a relatively complete theoretical and technical system for the surgical treatment of hepatocellular carcinoma, hepatobiliary stones, and traumatic bile duct strictures. When conducting laboratory tests on patients, hepatobiliary oncology surgeons need to use drainage and sampling equipment to perform puncture sampling.

[0003] A biopsy, a common medical surgical term, is a diagnostic and therapeutic technique that involves inserting a needle into a body cavity to extract secretions for testing, injecting gas or contrast agents into the cavity for imaging examinations, or injecting drugs into the cavity. Liver biopsy is short for liver biopsy. Liver biopsy pathology is primarily used for the differential diagnosis of various liver diseases, such as identifying the nature and cause of jaundice, understanding the degree and activity of liver lesions, providing etiological diagnostic evidence for various types of viral hepatitis, detecting early, quiescent, or compensated cirrhosis, and assessing clinical efficacy. It is internationally recognized as the "gold standard" for determining the severity of liver fibrosis. In addition, liver biopsy can also be used for diagnostic treatments, such as draining pus from liver abscesses, aspirating fluid from liver cysts, and injecting drugs or anhydrous alcohol into liver cancer tumors.

[0004] Chinese Patent Application No. 202020242398.0 discloses a tumor sampler, including a needle barrel assembly, a sampling assembly, a positioning assembly, and an adjustment assembly. The sampling assembly is disposed within and penetrates the needle barrel assembly. The positioning assembly is disposed at one end of the needle barrel assembly. The adjustment assembly is disposed within the needle barrel assembly. The sampling assembly includes a puncture module and a sampling needle. The puncture module includes a first handle, a sleeve, and a puncture needle. The first handle is disposed at one end of the sleeve, and the puncture needle is disposed at the other end of the sleeve. The sleeve is inserted into the needle barrel assembly. The sampling module includes a squeezing block, a connecting rod, and a sampling needle. The squeezing block is mounted on one end of the connecting rod, and the sampling needle is disposed at the other end of the connecting rod. The connecting rod is inserted into the sleeve, and the two are movably connected. The sampling needle is inserted into the puncture needle. The sampling needle includes a needle body, a first blade, and a second blade. One end of the needle body is fixedly connected to the connecting rod, and the other end of the needle body is fixedly connected to one end of the first blade. The other end of the first blade is provided with the second blade.

[0005] This tumor sampler can quickly extract a portion of tumor tissue using its sampling component, without causing excessive fragmentation of tumor cells in the sample. Its positioning component accurately determines the puncture site on the body surface, ensuring a constant insertion angle and position of the needle. The adjustment component quickly and accurately determines the depth of needle insertion, effectively avoiding inaccurate insertion depth and significantly improving the quality of tumor sampling. However, this tumor sampler cannot adjust the drainage pressure, and the drainage pressure is unstable, resulting in a slow sampling and drainage process. Summary of the Invention

[0006] In view of the technical problem in the prior art, the tumor sampler cannot adjust the drainage pressure and the drainage pressure is unstable during the sampling and drainage process, resulting in slow sampling and drainage.

[0007] Technical Concept: This invention provides a novel tumor tissue sampling device. Existing puncture sampling devices cannot control the pressure of puncture and drainage, resulting in unstable and slow puncture and drainage. The innovative concept of this application lies in achieving puncture and sampling through two pressure differences. First, external gas is drawn into the piston barrel and then further transported to the buffer barrel to buffer the gas and stabilize the gas pressure. The puncture needle is driven to perform puncture using the principle of a single pressure difference. Then, the gear and rack meshing linkage drives the second baffle to move to further form a pressure difference, thereby using the air pressure to achieve the aspiration and storage of sampled tissue.

[0008] To achieve the above objectives, the technical solution adopted by the present invention is as follows: A tumor tissue sampling device includes a sampling shell, wherein an air extraction mechanism, a buffer mechanism, a puncture mechanism, and an aspiration sampling mechanism are arranged sequentially from top to bottom inside the sampling shell. The buffer mechanism is connected above an air extraction mechanism that changes the air pressure inside the cavity by moving up and down a pressure regulating component, and below an air-pressure-driven puncture mechanism. The puncture mechanism is engaged with a sampling mechanism on its left side, which uses air pressure difference to achieve sampling.

[0009] In the above technical solution, the sampling shell is made of transparent acrylic. After being placed at the patient's puncture site, the position of the needle can be observed at any time through the transparent acrylic sampling shell. The needle can be inserted more accurately by contacting the target area through the base.

[0010] Furthermore, the air extraction mechanism includes an air intake unit on the left and an air extraction unit on the right. The air intake unit completes air intake by changing the air pressure by moving the pressure regulating component in the air extraction unit up and down.

[0011] Specifically, the air intake unit includes: an air extraction tank with an air inlet at the left end; One air intake check valve is slidably installed inside the air intake pipe on the left side of the suction tank; one end of spring A is fixedly connected to one air intake check valve, and the other end is fixedly connected inside the suction tank.

[0012] More specifically, the vacuum unit includes: a crank handle, rotatably connected to the upper end of the sampling housing; The piston barrel is fixedly connected to a buffer mechanism at its lower end and to a suction barrel at its left end; the piston connecting rod is connected to the crank handle pin at its upper end and to a piston at its lower end.

[0013] It should be noted that the piston connecting rod is provided with multiple adjustment holes. By adjusting the position of the rocker arm and the piston connecting rod pin, the range of motion of the piston can be adjusted, thereby adjusting the stroke of puncture or aspiration, and thus affecting the intensity. By controlling the rotation speed of the rocker arm, the speed of the aspiration process can be controlled.

[0014] Furthermore, the buffer mechanism includes an external gas buffer tank and an internal buffer unit, wherein the buffer unit buffers the static pressure of the gas in the buffer tank.

[0015] In detail, the buffer mechanism includes: a gas buffer tank, with a piston tank fixedly connected to the upper end and a puncture mechanism fixedly connected to the lower end; an air inlet one-way valve II, which is slidably disposed at the lower port of the piston tank; and a spring B, with one end fixedly connected to the air inlet one-way valve II and the other end fixedly connected to the gas buffer tank through a connecting block.

[0016] Furthermore, the puncture mechanism includes a lower puncture needle and an upper pushing unit that pushes the puncture needle to complete the puncture.

[0017] Furthermore, the puncture unit includes a transmission module on the left and a lifting and pushing module on the right, wherein the transmission module and the lifting and pushing module are slidably connected.

[0018] In particular, the lifting and pushing module includes: a puncture cannula, with a gas buffer tank fixedly connected to its upper end; a baffle plate, which is slidably connected to the transmission module through a slot on the left side of the puncture cannula; and a spring C, with the baffle plate connected to its upper end and the puncture needle connected to its lower end.

[0019] The transmission module includes: a rack, which is slidably disposed on the left side of the puncture cannula and has a clearance groove on the side close to the puncture cannula; and a clearance groove, wherein the baffle extends through a slot on the left side of the puncture cannula and slides into the clearance groove.

[0020] In detail, after the gas in the gas buffer tank enters the puncture cannula, it pushes the baffle to slide downward along the relief groove, compressing the spring C, and the elastic force pushes the puncture needle to perform puncture.

[0021] Furthermore, the aspiration sampling mechanism includes a drainage tube connected to the puncture needle and an aspiration unit that engages with the transmission module.

[0022] Specifically, the suction unit includes: a sampling bucket with a drainage tube inside; a second rack slidably disposed on the right side of the sampling bucket; and gears on the left and right sides respectively meshing with the second rack and the first rack. Baffle 2 is slidably installed in the sampling bucket and its right end is connected to rack 2.

[0023] In the above technical solution, the puncture is completed when the baffle slides to the bottom of the relief groove. At this time, the baffle pushes the rack to move downward, the rack drives the gear to rotate, the gear meshes and drives the rack to slide upward, which in turn drives the baffle to move upward, so that the air pressure in the sampling bucket decreases and the tissue is drawn from the drainage tube into the sampling bucket for storage.

[0024] Compared with the prior art, the beneficial effects of the present invention are: 1. This invention controls the air pressure of the internal mechanism of the sampling housing by rotating a crank handle connected to the upper part of the sampling housing, thereby achieving the technical effect of puncture sampling through air pressure difference. The operation is simple and convenient. 2. This invention uses a piston in the suction tank to extract and control the pressure of gas. The gas then enters a gas buffer tank to buffer the static pressure. The stable gas pressure then pushes the puncture needle to puncture, making the puncture more accurate and successful in one go. Furthermore, the gear and rack meshing movement creates a pressure difference between the sampling bucket and the sampling shell, enabling tissue extraction and achieving a controllable and rapid puncture sampling effect.

[0025] 3. The present invention allows for observation of the needle position at any time by setting a transparent acrylic sampling shell, and the needle can be inserted more accurately by contacting the target area through the base.

[0026] 4. The present invention has multiple adjustment holes on the piston rod. By adjusting the position of the rocker handle and the piston rod pin, the movement range of the piston can be adjusted, thereby adjusting the stroke of puncture or aspiration, and thus affecting the intensity. By controlling the rotation speed of the rocker handle, the speed of the aspiration process can be controlled. Attached Figure Description

[0027] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0028] Figure 1 This is a top-view perspective view of the present invention; Figure 2 This is a bottom-view perspective view of the present invention; Figure 3 This is a schematic diagram of the right-side structure of the present invention; Figure 4 For the present invention Figure 3 A cross-sectional view along the AA direction; Figure 5 This is a schematic diagram of the main structure of the present invention; Figure 6 For the present invention Figure 5 Cross-sectional view along the BB direction; Figure 7 This is a top view of the present invention; Figure 8 This is a bottom view of the present invention; Figure 9 For the present invention Figure 4 Enlarged view of the circled area; Figure 10 For the present invention Figure 6 Sectional view along the DD direction; Figure 11 This is a perspective view of the buffer mechanism of the present invention; Figure 12 For the present invention Figure 11 The main view; Figure 13 For the present invention Figure 12 A bottom view; In the diagram: 1. Suction mechanism; 11. Handle; 12. Piston barrel; 13. Piston connecting rod; 14. Piston; 15. Suction tank; 16. Air inlet; 17. Inlet one-way valve; 18. Spring A; 2. Buffer mechanism; 21. Gas buffer tank; 22. Inlet one-way valve; 23. Spring B; 24. Connecting block; 3. Puncture mechanism; 31. Puncture cannula; 32. Rack one; 33. Relief groove; 34. Baffle one; 35. Spring C; 36. Puncture needle; 4. Sampling mechanism; 41. Sampling barrel; 42. Gear; 43. Rack two; 44. Baffle two; 45. Drainage tube. Detailed Implementation

[0029] To enable those skilled in the art to better understand the technical solutions of the present invention, the technical solutions of the present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0030] In the description of this invention, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "front end", "rear end", "inner side", "outer side", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0031] In the description of this application, it should also be noted that, unless otherwise expressly specified and limited, the terms "set up," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0032] The inventors discovered that with the advancement of medicine, puncture sampling can reveal the process and extent of diseases such as cancer, and further determine the treatment plan based on the sampled tissue. However, existing puncture sampling devices cannot control the air pressure of puncture drainage, resulting in an unstable or inaccurate puncture process and a slow drainage sampling speed.

[0033] Based on the above findings, this application provides a tumor tissue sampling device, including a sampling shell, wherein an air extraction mechanism 1, a buffer mechanism 2, a puncture mechanism 3 and an aspiration sampling mechanism 4 are arranged sequentially from top to bottom inside the sampling shell; the air extraction mechanism 1 is connected above the buffer mechanism 2 and the puncture mechanism 3 is connected below the buffer mechanism 2; the aspiration sampling mechanism 4 is engaged on the left side of the puncture mechanism 3. Example 1

[0034] Reference Figure 1-10 As shown, this application provides a tumor tissue sampling device, including a sampling shell. Inside the sampling shell, from top to bottom, there are a suction mechanism 1, a buffer mechanism 2, a puncture mechanism 3, and an aspiration sampling mechanism 4. The upper part of the buffer mechanism 2 is connected to the suction mechanism 1, which changes the air pressure in the cavity by moving up and down through a pressure regulating component, and the lower part is connected to the puncture mechanism 3, which pushes the puncture through air pressure. The left side of the puncture mechanism 3 is engaged with the aspiration sampling mechanism 4, which achieves sampling through air pressure difference.

[0035] In the above technical solution, the air extraction mechanism 1, the puncture mechanism 3, the sampling mechanism 4 and the sampling shell are all fixedly connected and their relative positions remain unchanged.

[0036] Furthermore, the air extraction mechanism 1 includes an air intake unit on the left and an air extraction unit on the right. The air intake unit changes the air pressure by moving the pressure regulating component in the air extraction unit up and down to complete the air intake.

[0037] Specifically, the intake unit and the extraction unit are fixedly connected by an air supply pipe, and the gas in the intake unit can be delivered to the extraction unit.

[0038] Specifically, the air intake unit includes: an air extraction tank 15, with an air inlet 16 at the left end; An air intake check valve 17 is slidably installed inside the air intake pipe on the left side of the suction tank 15; a spring A18 is fixedly connected at one end to the air intake check valve 17 and at the other end to the suction tank 15.

[0039] More specifically, the suction unit includes: a crank handle 11, rotatably connected to the upper end of the sampling housing; a piston barrel 12, with a buffer mechanism 2 fixedly connected to the lower end and a suction barrel 15 fixedly connected to the left end; and a piston connecting rod 13, with the upper end connected to the crank handle 11 by a pin and the lower end connected to a piston 14.

[0040] It should be noted that the piston connecting rod 13 is provided with multiple adjustment holes. By adjusting the position of the rocker handle 11 and the piston connecting rod 13 shaft pin, the range of motion of the piston 14 can be adjusted.

[0041] During the specific operation, medical staff manually crank the handle 11. The handle 11 is connected by a pin and drives the piston rod 13 to move up and down. The piston rod 13 drives the piston 14 to move up and down synchronously with the piston rod 13. The movement of the piston 14 causes a change in the air pressure in the piston barrel 12, making the air pressure in the piston barrel 12 smaller. At this time, the external air pressure is greater than the air pressure in the piston barrel 12, which causes the external gas to enter the air intake pipe through the air inlet 16. The gas pushes the air intake one-way valve 17 to slide into the air extraction tank 15 in the air intake pipe. At this time, the spring A is compressed, and the gas enters the gas delivery pipe from the air intake pipe and is finally delivered to the piston barrel 12.

[0042] Furthermore, the puncture mechanism 3 includes a lower puncture needle 36 and an upper pushing unit that pushes the puncture needle 36 to complete the puncture.

[0043] Furthermore, the puncture unit includes a transmission module on the left and a lifting and pushing module on the right, wherein the transmission module and the lifting and pushing module are slidably connected.

[0044] In detail, the lifting and pushing module includes: a puncture sleeve 31, with a gas buffer tank 21 fixedly connected to its upper end; a baffle 34, which is slidably connected to the transmission module through a slot on the left side of the puncture sleeve 31; and a spring C35, with the baffle 34 connected to its upper end and the puncture needle 36 connected to its lower end.

[0045] The transmission module includes: a rack 32, which is slidably disposed on the left side of the puncture tube 31 and has a relief groove 33 on the side close to the puncture tube 31; the relief groove 33 is formed by the baffle 34 extending into the relief groove 33 through the slot opened on the left side of the puncture tube 31.

[0046] The specific process is as follows: After the gas in the piston barrel 12 enters the puncture sleeve 31, the gas pushes the baffle 34 to move downward in the puncture sleeve 31. At this time, one end of the baffle 34 extends through the slot opened on the left side of the puncture sleeve 31 to slide in the relief groove 33 set on the rack 32. At this time, the spring C35 is compressed, and the elastic force of the spring C35 pushes the puncture needle 36 to complete the puncture.

[0047] In the above technical solution, the aspiration sampling mechanism 4 includes a drainage tube 45 connected to the puncture needle 36 and an aspiration unit that meshes with the transmission module.

[0048] More specifically, the suction unit includes: a sampling bucket 41, with a drainage tube 45 inside; a second rack 43, which is slidably disposed on the right side of the sampling bucket 41; a gear 42, which meshes with the second rack 43 and the first rack 32 on the left and right sides respectively; and a second baffle 44, which is slidably disposed in the sampling bucket 41 and connected to the second rack 43 on the right end.

[0049] The specific implementation process is as follows: When the baffle 34 slides to the bottom of the clearance groove 33, the puncture needle 36 completes the puncture. At this time, the gas pushes the baffle 34 to continue moving downward. The baffle 34 drives the rack 32 to slide downward. Both racks 32 and 43 mesh with gear 42. The downward movement of rack 32 drives the meshing and rotation of gear 42. The rotation of gear 42 then drives rack 43 to slide upward. The movement directions of racks 32 and 43 are opposite. Rack 43 drives the baffle 44 to move upward, thereby reducing the air pressure in the sampling container 41. This allows the tumor tissue to enter the drainage tube 45 through the puncture needle 36 and finally be sucked into the sampling container 41 for storage, thus completing the puncture sampling process. Example 2

[0050] Based on Embodiment 1, the present invention provides a buffer mechanism 2 between the air extraction mechanism 1 and the puncture mechanism 3, which can buffer the static pressure of the gas in the air extraction mechanism 1. The stable gas pressure makes the puncture by the puncture mechanism 3 more stable and accurate.

[0051] Reference Figure 4 , 6 As shown in Figures 11-13, a tumor tissue sampling device includes a sampling shell, and the sampling shell is provided with an air extraction mechanism 1, a buffer mechanism 2, a puncture mechanism 3 and an aspiration sampling mechanism 4 arranged sequentially from top to bottom. The buffer mechanism 2 is connected to the air extraction mechanism 1 above and the puncture mechanism 3 below.

[0052] In the above technical solution, the buffer mechanism 2 includes an external gas buffer tank 21 and an internal buffer unit, wherein the buffer unit buffers the static pressure of the gas in the buffer tank 21.

[0053] Specifically, the buffer unit includes a buffer part that is slidably sleeved on the lower port of the piston barrel 12, and a connecting part that is connected at one end to the buffer part and at the other end to the buffer barrel 21.

[0054] More specifically, the buffer section includes: an intake one-way valve 22, which is slidably disposed at the lower port of the piston barrel 12; and a spring B23, one end of which is fixedly connected to the intake one-way valve 22, and the other end of which is fixedly connected to the connecting section.

[0055] It should be noted that the connecting block 24 is a circular block structure and has a soft air vent. The lower end face of the connecting block 24 is provided with a connecting seat that connects to the gas buffer tank 21.

[0056] By adopting the above technical solution, the gas in the piston barrel 12 pushes the air inlet check valve 22 located at the lower port of the piston barrel 12 to slide downward. At this time, the spring B23 is compressed, and the gas enters the gas buffer barrel 21 from the piston barrel 12. The gas pressure entering the gas buffer barrel 21 is further buffered, so that the gas pressure in the gas buffer barrel 21 is in a stable state. In this way, the gas with buffered static pressure will push the puncture needle 36 to perform puncture more stably.

[0057] Specific application examples: Taking hepatobiliary surgery as an example, this paper describes in detail the specific application of a tumor tissue sampling device in hepatobiliary surgery.

[0058] Hepatobiliary surgery primarily studies hepatocellular carcinoma, hepatobiliary stones, post-hepatitis cirrhosis, and acute liver failure caused by severe hepatitis, which are major diseases that seriously threaten the health of Chinese people. Combining the characteristics of hepatobiliary diseases in the Chinese population, China's hepatobiliary surgery department has developed a relatively complete theoretical and technical system for the surgical treatment of hepatocellular carcinoma, hepatobiliary stones, and traumatic bile duct strictures. When conducting laboratory tests on patients, hepatobiliary oncology surgeons need to use drainage and sampling equipment to perform puncture sampling.

[0059] Liver biopsy refers to the procedure of inserting a needle into the liver under the guidance of external ultrasound or CT scans. Its main purposes include diagnosis, treatment, and prognostic assessment. For example, in a liver biopsy, guided by external ultrasound, a needle is inserted directly through the skin to access the liver and extract pathological tissue. This tissue is then subjected to immunohistochemistry or microscopic examination to determine if any abnormal lesions are present.

[0060] If a liver tumor cannot be definitively identified, a liver biopsy is performed to remove tumor tissue to determine its benign or malignant nature, as well as the specific pathological type of the tumor. If a liver abscess is present, a liver biopsy is performed to aspirate the pus from the abscess cavity, promoting healing. Additionally, intrahepatic bile duct puncture is performed for obstructive jaundice to drain bile and relieve jaundice. Biopsies are also performed for certain cases of unexplained cirrhosis, or after treatment to assess the effectiveness of the treatment. These are just some of the procedures involved.

[0061] Existing puncture and sampling devices cannot control the puncture and drainage pressure, and the drainage pressure is unstable, resulting in a slow sampling and drainage process.

[0062] Based on this, this application provides a tumor tissue sampling device. In clinical use, the sampling housing is placed at the site where the patient needs to be punctured through its bottom. Under the guidance of external ultrasound or CT, puncture is performed on the liver inside the body. The specific operation process is as follows: medical staff manually crank the handle 11. The handle 11 is connected by a pin and drives the piston rod 13 to move up and down. The piston rod 13 drives the piston 14 to move up and down synchronously with the piston rod 13. The movement of the piston 14 causes a change in the air pressure in the piston barrel 12, making the air pressure inside the piston barrel 12 lower. At this time, the external air pressure is greater than the air pressure inside the piston barrel 12, so that the external gas enters the air inlet pipe through the air inlet 16. The gas pushes the air inlet one-way valve 17 to slide into the air suction tank 15 in the air inlet pipe. At this time, the spring A is compressed, and the gas enters the gas delivery pipe from the air inlet pipe and is finally delivered to the piston barrel 12.

[0063] Furthermore, the gas inside the piston barrel 12 pushes the air inlet check valve 22 located at the lower port of the piston barrel 12 to slide downward. At this time, the spring B23 is compressed, and the gas enters the gas buffer barrel 21 from the piston barrel 12. The gas pressure entering the gas buffer barrel 21 is further buffered, so that the gas pressure inside the gas buffer barrel 21 is in a stable state. In this way, the gas with buffered static pressure will push the puncture needle 36 to perform puncture more stably.

[0064] Furthermore, after the gas in the gas buffer tank 21 enters the puncture cannula 31, the gas pushes the baffle 34 to move downward in the puncture cannula 31. At this time, one end of the baffle 34 extends through the slot on the left side of the puncture cannula 31 to slide into the relief groove 33 provided on the rack 32. At this time, the spring C35 is compressed, and the elastic force of the spring C35 pushes the puncture needle 36 to complete the puncture.

[0065] Then, when the baffle 34 slides to the bottom of the clearance groove 33, the puncture needle 36 completes the puncture. At this time, the gas pushes the baffle 34 to continue moving downward. The baffle 34 drives the rack 32 to slide downward. Both racks 32 and 43 mesh with gear 42. The downward movement of rack 32 drives the meshing and rotation of gear 42. The rotation of gear 42 then drives rack 43 to slide upward. The directions of movement of racks 32 and 43 are opposite. Rack 43 drives the baffle 44 to move upward, thereby reducing the air pressure in the sampling container 41. This allows the tumor tissue to enter the drainage tube 45 through the puncture needle 36 and finally be aspirated into the sampling container 41 for storage, thus completing the puncture sampling process.

[0066] It should be noted that those skilled in the art can make various modifications and improvements without departing from the structure of this invention, and these should also be considered within the scope of protection of this invention. These modifications and improvements will not affect the effectiveness of the invention or the practicality of the patent. The scope of protection claimed in this application shall be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A tumor tissue sampling device, comprising a sampling housing, characterized in that: The sampling housing is equipped with an air extraction mechanism (1), a buffer mechanism (2), a puncture mechanism (3), and an aspiration sampling mechanism (4). The buffer mechanism (2) is connected above to an air extraction mechanism (1) that changes the air pressure in the cavity by moving up and down through a pressure regulating component, and below to a puncture mechanism (3) that pushes the puncture through air pressure. The puncture mechanism (3) is engaged with a sampling mechanism (4) on the left side, which achieves sampling through air pressure difference. The puncture mechanism (3) includes a lower puncture needle (36) and an upper push unit that pushes the puncture needle (36) to complete the puncture. The pushing unit includes a transmission module on the left and a lifting pushing module on the right, and the transmission module and the lifting pushing module are slidably connected. The lifting and pushing module includes: The upper end of the puncture cannula (31) is fixedly connected to the gas buffer tank (21). The baffle (34) is slidably connected to the transmission module through the slot opened on the left side of the puncture sleeve (31); Spring C (35) has a baffle (34) connected to its upper end and a puncture needle (36) connected to its lower end. The transmission module includes: The rack (32) is slidably disposed on the left side of the puncture cannula (31) and has a relief groove (33) on the side close to the puncture cannula (31). The baffle (34) extends into the relief groove (33) through the slot opened on the left side of the piercing sleeve (31) and slides therein; The aspiration sampling mechanism (4) includes a drainage tube (45) connected to the puncture needle (36) and an aspiration unit that meshes with the transmission module; The suction unit includes: The sampling bucket (41) has a drainage tube (45) inside. Rack 2 (43) is slidably positioned on the right side of the sampling bucket (41); The gear (42) meshes with rack two (43) and rack one (32) on the left and right sides respectively; Baffle 2 (44) is slidably set in the sampling bucket (41) and its right end is connected to rack 2 (43); After the gas enters the puncture cannula (31), the gas pushes the baffle (34) to move downward in the puncture cannula (31). At this time, one end of the baffle (34) extends through the slot on the left side of the puncture cannula (31) to slide in the relief groove (33) provided on the rack (32). At this time, the spring C (35) is compressed, and the elastic force of the spring C (35) pushes the puncture needle (36) to puncture. When the baffle (34) slides to the bottom of the relief groove (33), the puncture needle (36) completes the puncture. At this time, the gas pushes the baffle (34) to continue to move downward. The baffle (34) drives the rack (32) to slide downward. The rack (32) and the rack (43) are both engaged with the gear (42). The downward movement of the rack (32) drives the gear (42) to rotate. The rotation of the gear (42) then drives the rack (43) to slide upward. The rack (32) and the rack (43) move in opposite directions. The rack (43) drives the baffle (44) to move upward, which in turn reduces the air pressure in the sampling bucket (41). This allows the tumor tissue to enter the drainage tube (45) through the puncture needle (36) and finally be sucked into the sampling bucket (41) for storage, thus completing the puncture sampling process.

2. The tumor tissue sampling device according to claim 1, characterized in that: The air extraction mechanism (1) includes an air intake unit on the left and an air extraction unit on the right. The air intake unit changes the air pressure by moving the pressure regulating component in the air extraction unit up and down to complete the air intake.

3. The tumor tissue sampling device according to claim 2, characterized in that: The buffer mechanism (2) includes an external gas buffer tank (21) and an internal buffer unit, which buffers the static pressure of the gas in the gas buffer tank (21).

4. A tumor tissue sampling device according to claim 3, characterized in that: The buffer unit includes a buffer part that is slidably sleeved on the lower port of the piston barrel (12), and a connecting part that is connected at one end to the buffer part and at the other end to the gas buffer barrel (21).

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