Intraocular lens

Abstract

The application discloses an artificial lens, which comprises a capsule, a cavity formed in the capsule, a sealing valve arranged on the capsule, a silica gel sealing valve, and a parylene layer arranged on the outer surface of the sealing valve. Thus, the silica gel sealing valve of the application can be self-sealed under the protection of the rigid parylene layer, thereby playing a sealing and leakage-proof role for a long time, preventing the optical fluid medium filled in the capsule from leaking, and thereby guaranteeing the reliability and safety of the artificial lens.

Description

Technical Field

[0001] This invention relates to the field of ophthalmic medical device technology, and in particular to an artificial lens. Background Technology

[0002] Cataract extraction combined with intraocular lens implantation remains the only effective treatment for cataracts for the foreseeable future. While implantation of a traditional monofocal intraocular lens after cataract surgery can provide excellent distance vision, the lack of focusing capability of monofocal intraocular lenses generally results in postoperative hyperopia, requiring patients to rely on glasses for various close-range tasks.

[0003] Multifocal intraocular lenses employ a unique optical design that can simultaneously form two or more focal points within the eye. After surgery, patients can adjust the size of their pupils to select different focal points to meet their needs for both near and far vision, thus reducing the rate of wearing glasses after cataract surgery. However, the presence of multiple focal points can cause drawbacks such as halos and glare for patients.

[0004] In recent years, many scholars have attempted to design adjustable intraocular lenses (IOLs) by altering the amount or type of optical fluid medium (such as silicone oil) within the capsular bag, thereby changing the shape or optical path of the IOL and thus adjusting its refractive power. However, ensuring the long-term sealing of the optical fluid medium after injection remains a challenge that needs to be addressed by those skilled in the art. Summary of the Invention

[0005] The present invention aims to at least solve one of the technical problems existing in the prior art. Therefore, one object of the present invention is to provide an intraocular lens that can effectively prevent leakage of the optical fluid medium filling the intraocular lens.

[0006] An intraocular lens according to an embodiment of the present invention includes: a capsule having a chamber formed therein; a sealing valve disposed on the capsule, the sealing valve being a silicone sealing valve; and a phenelzine layer disposed on the outer surface of the sealing valve.

[0007] Therefore, by adjusting the amount or type of optical fluid medium filling the intraocular lens (IOL), the shape or optical path of the IOL can be altered, thereby adjusting its refractive power. Furthermore, the silicone sealing valve, protected by a rigid phenelzine layer, can self-close, providing a long-term leak-proof seal and preventing leakage of the optical fluid medium within the capsule, thus ensuring the reliability and safety of the IOL.

[0008] According to some embodiments of the present invention, the pyreline layer covers the outer surface of the sealing valve and also partially covers the outer surface of the bladder.

[0009] According to some embodiments of the present invention, the sealing valve includes: a ring body and a body, the ring body being disposed on the bladder body, the body being disposed within the ring body, and the hardness of the body being less than the hardness of the ring body.

[0010] According to some embodiments of the present invention, the pyreline layer is disposed on the outer surfaces of both the ring and the body.

[0011] According to some embodiments of the present invention, the ring body is a hard silicone body, and the body is a soft silicone body.

[0012] According to some embodiments of the present invention, the hardness of the ring is between Shore 80A and 90A, and the hardness of the body is between Shore 20A and 40A.

[0013] According to some embodiments of the present invention, the hardness of the body is less than or equal to the hardness of the capsule.

[0014] According to some embodiments of the present invention, the number of sealing valves is two, the number of perylene layers is two, and the two sealing valves and the two perylene layers are arranged in a one-to-one correspondence.

[0015] According to some embodiments of the present invention, the two sealing valves are symmetrically arranged about the central axis of the bladder.

[0016] According to some embodiments of the present invention, the capsule has an equator, and the capsule includes an anterior capsule and a posterior capsule connected together, wherein the connection between the anterior capsule and the posterior capsule avoids the equator.

[0017] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0018] The above and / or additional aspects and advantages of the present invention will become apparent and readily understood from the description of the embodiments taken in conjunction with the following drawings, in which:

[0019] Figure 1 This is a cross-sectional view of an intraocular lens according to an embodiment of the present invention;

[0020] Figure 2 This is a cross-sectional view of an intraocular lens containing two sealing valves according to an embodiment of the present invention;

[0021] Figure 3This is a cross-sectional view of an intraocular lens containing a groove according to an embodiment of the present invention;

[0022] Figure 4 This is a cross-sectional view of an intraocular lens containing an optical convex lens according to an embodiment of the present invention;

[0023] Figure 5 This is a schematic diagram of the structure of an intraocular lens containing a haptic according to an embodiment of the present invention;

[0024] Figure 6 This is a schematic diagram of the structure for separating an intraocular lens according to an embodiment of the present invention;

[0025] Figure 7 This is a schematic diagram of the structure of the anterior capsule and posterior capsule in conjunction according to an embodiment of the present invention;

[0026] Figure 8 This is a cross-sectional view of the anterior and posterior capsules in conjunction according to an embodiment of the present invention;

[0027] Figure 9 This is a schematic diagram of the structure of an intraocular lens in the eye according to an embodiment of the present invention.

[0028] Figure label:

[0029] 100. Intraocular lens;

[0030] 10. Capsule body; 11. Groove; 12. Anterior capsule body; 13. Posterior capsule body; 14. Equator; 15. Optical convex lens;

[0031] 20. Sealing valve; 21. Ring body; 22. Body;

[0032] 30. Perylene Layer;

[0033] 40. Loop body; 41. Front connecting arm; 42. Rear connecting arm; 43. Free end;

[0034] 50. Seam thread. Detailed Implementation

[0035] The embodiments of the present invention are described in detail below, and the embodiments described with reference to the accompanying drawings are exemplary.

[0036] The following is for reference. Figures 1-9 The artificial lens 100 according to an embodiment of the present invention includes: a capsule 10, a sealing valve 20, and a phenelzine layer 30. A chamber is formed within the capsule 10. The sealing valve 20 is disposed on the capsule 10 and is a silicone sealing valve 20. The phenelzine layer 30 is disposed on the outer surface of the sealing valve 20. The capsule 10 may be made of silicone, siloxane, fluorosilane, hydrophilic or hydrophobic acrylate, preferably silicone.

[0037] Specifically, such asFigure 1 As shown, a valve hole is provided on the capsule 10, and a sealing valve 20 is disposed in the valve hole. A pyrene layer 30 (preferably pyrene C, and can be produced by vapor deposition) is provided on the outer surface of the sealing valve 20. The Young's modulus and hardness of the pyrene layer 30 are significantly higher than those of the silicone sealing valve 20. Moreover, the pyrene layer 30 has good adhesion to the silicone sealing valve 20, which is equivalent to adding a reinforcing baffle to the outside of the silicone sealing valve 20. Therefore, when the injection needle is withdrawn, the optical fluid medium (silicone oil) inside the sealing valve 20 can generate outward pressure on the silicone sealing valve 20. The outward pressure can cause the silicone sealing valve 20 to self-close under the protection of the rigid pyrene layer 30, thereby providing a long-term sealing and leak-proof function.

[0038] The intraocular lens 100 of this invention can change its shape or optical path by adjusting the amount of optical fluid medium filling the capsule 10 or by changing the type of optical fluid medium, thereby adjusting the refractive power of the intraocular lens 100. Furthermore, the sealing valve 20 and the phenelzine layer 30 on the capsule 10 can prevent leakage of the optical fluid medium filling the capsule 10, and can also avoid deformation and stress concentration in the capsule 10, thereby ensuring the reliability and safety of the intraocular lens 100.

[0039] like Figure 1 As shown, the pyrene layer 30 covers the outer surface of the sealing valve 20, and the pyrene layer 30 also partially covers the outer surface of the bladder 10, which increases the contact area between the pyrene layer 30 and the sealing valve 20 and can avoid stress concentration at the connection between the sealing valve 20 and the bladder 10.

[0040] The sealing valve 20 includes an annular body 21 and a body 22. The annular body 21 is disposed on the capsule 10, and the body 22 is disposed inside the annular body 21. The hardness of the body 22 is less than that of the annular body 21. The body 22 is preferably circular, and the annular body 21 is preferably circular. When an optical fluid medium needs to be injected from the sealing valve 20, the lower hardness of the body 22 facilitates the insertion of the injection needle into the capsule 10, and makes it easier to achieve a seal after the injection needle is withdrawn, preventing leakage of the optical fluid medium. The higher hardness of the body 22 avoids deformation and stress concentration on the capsule 10 during injection, making the injection simpler and more reliable.

[0041] The Parylene layer 30 is simultaneously disposed on the outer surfaces of both the ring 21 and the body 22, resulting in a larger contact area. Preferably, the ring 21 is made of hard silicone, and the body 22 is made of soft silicone; the organic combination of the soft and hard silicone forms a closed whole. Specifically, the hardness of the ring 21 is between Shore A and 90 A, and the hardness of the body 22 is between Shore A and 40 A, which can prevent deformation of the body 22 and the capsule 10. Furthermore, the hardness of the body 22 can be less than or equal to the hardness of the capsule 10. Preferably, the body 22 and the capsule 10 are made of the same material, facilitating processing and manufacturing.

[0042] like Figure 2 As shown, there are two sealing valves 20 and two pyrene layers 30, with each valve corresponding to the other. One of the two sealing valves 20 is used for injection, while the other provides mechanical compensation and balance, and can also serve as a backup valve. Furthermore, the two sealing valves 20 can be positioned at different locations on the capsule 10, thus creating different injection paths and allowing injection in different directions for flexible operation. Preferably, the two sealing valves 20 are symmetrically arranged about the central axis of the capsule 10, which ensures uniform deformation of the optical area on the upper surface of the capsule 10.

[0043] like Figure 3 As shown, a groove 11 is provided in the middle of the posterior side of the capsule 10, facing the cavity, and the sealing valve 20 is spaced apart from the groove 11. The groove 11 reduces tissue contact between the artificial lens 100 and the posterior wall of the lens capsule and avoids the influence of allogeneic tissue hyperplasia. The spaced arrangement of the optical path sealing valve 20 and the groove 11 further avoids stress concentration.

[0044] like Figure 5 and Figure 6 As shown, the capsule 10 includes an anterior capsule 12 and a posterior capsule 13, which are connected together. A sealing valve 20 is disposed in the anterior capsule 12, and a groove 11 is provided in the middle of the posterior capsule 13. The anterior capsule 12 and the posterior capsule 13 can be bonded together to form a near-ellipsoidal structure that mimics the human lens.

[0045] In addition, a groove 11 may be provided in the middle of the anterior capsule 12. The groove 11 is formed by the inward recess in the middle of the anterior capsule 12. The inward recessed space of the groove 11 can reduce the tissue contact with the anterior wall of the lens capsule, thereby avoiding interference with the light path.

[0046] The groove 11 portion can be made of a silicone membrane with an initial power. The liquid filling the capsule 10 causes micro-deformation of this silicone membrane, thereby adjusting the overall power of the artificial lens 100. For example... Figure 4As shown, the bottom of the groove 11 of the anterior capsule 12 and / or the posterior capsule 13 is constructed as an optical convex lens 15, which can help with focusing and can be set according to actual needs.

[0047] The optical convex lens 15 is preferably made of PMMA (polymethyl methacrylate), which has the characteristics of high transparency and low refractive index. The hardness of the optical convex lens 15 is between Shore A and 90A, which can prevent the PMMA film from deforming.

[0048] The outer radius of curvature of the optical convex lens 15 on the anterior capsule 12 is ρ1, which satisfies the relationship: 9mm≤ρ1≤11mm. The outer radius of curvature of the optical convex lens 15 on the posterior capsule 13 is ρ2, which satisfies the relationship: 5mm≤ρ2≤7mm. During the filling of the optical fluid medium, the PMMA film layer of the optical convex lens 15 at the groove 11 of the anterior capsule 12 and the posterior capsule 13 hardly deforms. By adjusting the deformation of the capsule 10, the distance between the PMMA film layer at the groove 11 of the anterior capsule 12 and the PMMA film layer at the groove 11 of the posterior capsule 13 can be changed, thereby adjusting the optical path of the intraocular lens 100 and achieving the change of focal point.

[0049] like Figure 6 As shown, the capsule 10 has an equator 14 and includes an anterior capsule 12 and a posterior capsule 13 connected together. The connection point between the anterior capsule 12 and the posterior capsule 13 avoids the equator 14, meaning the area of ​​the connection point is smaller than the area of ​​the equator 14. The capsule 10 is an asymmetrical ellipsoid, with its diameter increasing from front to back, reaching its maximum value, and then decreasing backward. This maximum value is the equator 14. Because stress concentration or slight deformation is prone to occur at the equator 14, affecting refractive effect, the connection point between the anterior capsule 12 and the posterior capsule 13 is designed to avoid the equator 14, thus preventing deformation of the capsule 10.

[0050] like Figure 7As shown, the distance from the junction of the anterior capsule 12 and the posterior capsule 13 to the equator 14 is d, where d satisfies the relationship: 1mm ≤ d ≤ 1.5mm. Specifically, the junction is parallel to the plane of the equator 14, and the distance from the equator 14 ranges from 1mm to 1.5mm. The junction can form a suture line 50, which forms an integral ring. The junction of the anterior capsule 12 and the posterior capsule 13 is preferably located on the posterior side of the equator 14, but it can also be located on the anterior side of the equator 14, depending on the actual situation. Furthermore, the junction of the anterior capsule 12 and the posterior capsule 13 is positioned away from the equator 14. Through mechanical analysis, this reduces stress concentration and achieves good mechanical properties, thereby facilitating the adjustment of the refractive effect of the intraocular lens 100.

[0051] Furthermore, such as Figure 5 As shown, the intraocular lens 100 also includes a loop 40, which is connected to the equator 14. The loop 40 supports the capsule 10 within the lens capsule, is associated with the movement of the ciliary muscle, adjusts the shape of the capsule 10, and performs focusing movements. The loop 40 can be made of polyvinylidene fluoride (PVDF), polymethyl methacrylate (PMMA), polyimide, acrylate, etc.

[0052] like Figures 6-8 As shown, in another embodiment of the present invention, the loop 40 includes a front connecting arm 41, a rear connecting arm 42, and a free end 43. The front connecting arm 41 is connected to the outer surface of the front bladder 12, and the rear connecting arm 42 is connected to the outer surface of the rear bladder 13. The ends of the front connecting arm 41 and the rear connecting arm 42 form the free end 43, and there is an included angle between the front connecting arm 41 and the rear connecting arm 42. The loop 40 is generally Y-shaped. The connection point between the front connecting arm 41 and the front bladder 12 is located near the 1 / 2 position of the thickness of the front bladder 12. The specific connection position can be determined through mechanical simulation analysis and experimental verification to find the optimal stress position as the connection position of the loop 40.

[0053] In refractive adjustment, the angled structure of the anterior connecting arm 41 and the posterior connecting arm 42 facilitates balanced force distribution on the capsule 10 during refractive adjustment and allows for controllable deformation, thereby increasing the accuracy and effectiveness of refractive adjustment. Furthermore, the loop 40 can be fabricated as an anterior connecting arm 41 and a posterior connecting arm 42, and then the free ends 43 of the anterior connecting arm 41 and the posterior connecting arm 42 can be bonded together with silicone. Alternatively, the loop 40 can be made as a single unit using a stainless steel mold, and then bonded to the anterior capsule 12 and the posterior capsule 13 respectively using silicone, thereby improving the fabrication efficiency of the intraocular lens 100.

[0054] The number of loops 40 is at least two, and the at least two loops 40 are evenly distributed about the center of the capsule 10. In this way, the capsule 10 can be subjected to uniform force and the deformation can be controlled, thereby increasing the accuracy and effectiveness of refractive accommodation.

[0055] According to some embodiments of the present invention, the intraocular lens 100 further includes a pre-filler disposed within the cavity. The pre-filler is the aforementioned optical fluid medium, which can be injected into the cavity of the capsule 10. Suitable pre-fillers include silicone oil, silicone, ophthalmic sterile heavy water (perfluoronaphthene C10F18), sodium hyaluronate (healon GV), etc., with silicone oil being preferred. During surgery, additional filler can be added to the cavity of the capsule 10 until the desired shape or optical path is achieved.

[0056] Although embodiments of the invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. An artificial lens, characterized in that, include: A capsule, wherein a cavity is formed within the capsule; A sealing valve, wherein the sealing valve is disposed on the bladder body, and the sealing valve is a silicone sealing valve; as well as A perrelin layer is disposed on the outer surface of the sealing valve; The sealing valve includes: a ring body and a body body, the ring body being disposed on the bladder body, the body body being disposed within the ring body, the hardness of the body body being less than the hardness of the ring body, and the body body and the bladder body being made of the same material; The paraffin layer is disposed on the outer surface of both the ring and the body; The ring is made of hard silicone, and the body is made of soft silicone. The capsule has an equator and includes a front capsule and a rear capsule, the front capsule and the rear capsule are connected, and the connection between the front capsule and the rear capsule avoids the equator. The intraocular lens further includes a haptic body, which includes an anterior connecting arm, a posterior connecting arm, and a free end. The anterior connecting arm is connected to the outer surface of the anterior capsule, and the posterior connecting arm is connected to the outer surface of the posterior capsule. The ends of the anterior connecting arm and the posterior connecting arm form the free end, and there is an included angle between the anterior connecting arm and the posterior connecting arm.

2. The intraocular lens according to claim 1, characterized in that, The perylene layer covers the outer surface of the sealing valve and also partially covers the outer surface of the bladder.

3. The intraocular lens according to claim 1, characterized in that, The hardness of the ring is between Shore A 80A and 90A, and the hardness of the body is between Shore A 20A and 40A.

4. The intraocular lens according to any one of claims 1 to 2, characterized in that, The number of sealing valves is two, and the number of perylene layers is two, with the two sealing valves and the two perylene layers arranged in a one-to-one correspondence.

5. The intraocular lens according to claim 4, characterized in that, The two sealing valves are symmetrically arranged about the central axis of the bladder.

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