Use of 9,10-dihydroacridine derivatives in the gas phase detection of crack cocaine N-methylamphetamine or crack cocaine mimetic N-methylphenethylamine

CN117890340BActive Publication Date: 2026-07-21JILIN UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JILIN UNIVERSITY
Filing Date
2024-01-04
Publication Date
2026-07-21

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Abstract

The application provides application of 9,10-dihydroacridine derivatives in gas-phase fluorescence detection of crack or crack analog N-methylphenethylamine, and belongs to the technical field of fluorescence sensing. In the application, an electron acceptor group is introduced into the 9,10-dihydroacridine derivative to construct a donor-acceptor type (D-A) organic fluorescent material, which can effectively realize gas-phase fluorescence detection of N-methylphenethylamine (MPEA) and has the advantages of visualization, quantification, high efficiency, accuracy and repeatable detection. Specifically, the thin film fluorescence sensor shows a double-peak enhanced fluorescence response of MPEA gas at 420 nm and 520 nm, and the fluorescence color can be observed to change from blue to cyan under excitation of an ultraviolet lamp; the thin film sensor is combined with a smart phone, the fluorescence signal can be converted into a quantifiable color difference value (Delta E) through digital means, and then on-site visual quantitative detection of MPEA is realized.
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