Traditional Chinese medicine patch with cough relieving and asthma relieving effects and preparation method thereof

Abstract

The application discloses a traditional Chinese medicine patch with effects of relieving cough and asthma and a preparation method thereof. The traditional Chinese medicine paste used in the traditional Chinese medicine patch comprises the following raw materials in parts by weight: honeysuckle 40-50 parts, Zhejiang fritillary bulb 25-35 parts, wind-preventing plant 25-35 parts, Stachys 40-50 parts, momordica grosvenori 25-35 parts, platycodon 10-20 parts, aletris 40-50 parts, loquat leaf 70-80 parts, perilla 40-50 parts, forsythia 40-50 parts, licorice 25-35 parts, frankincense 10-20 parts, myrrh 10-20 parts, yellow rice wine 10-20 parts, old vinegar 10-20 parts, lubricant 30-40 parts and honey 400-500 parts. The traditional Chinese medicine combination of honeysuckle, Zhebei, wind-preventing plant, Stachys, momordica grosvenori, platycodon, aletris, loquat leaf, perilla, forsythia, licorice, frankincense and myrrh is used as the functional component for relieving cough and asthma. The mouse test proves that the traditional Chinese medicine patch has very significant antitussive effect. The human efficacy test proves that the traditional Chinese medicine patch has significant curative effect on infantile cough, and the total effective rate is as high as 93.3%, and the cough symptoms, asthma and other accompanying symptoms of the children with constipation are obviously improved.

Description

Technical Field

[0001] This invention belongs to the field of medical and health care products technology, specifically relating to a traditional Chinese medicine patch with antitussive and antiasthmatic effects and its preparation method. Background Technology

[0002] Coughing is the most common complaint and cause of respiratory diseases in children, and its incidence is on the rise. Traditional Chinese medicine believes that the pathogenesis of cough is due to impaired lung function and upward flow of lung qi, caused by external pathogens invading the lungs or internal organ damage. Because children's organs are delicate and easily susceptible to external pathogens, leading to impaired lung function, the incidence of cough is even higher.

[0003] Clinically, children's coughs differ significantly from adult coughs, severely impacting children's physical and mental health, learning, and daily life. This can cause parental anxiety and lead to unnecessary unnecessary tests and financial waste. Currently, Western medicine primarily treats coughs with anti-infection and expectorant therapies, but the clinical results are not ideal. Furthermore, parents worry that excessive use of antibiotics and cough suppressants may have adverse effects on their children.

[0004] Traditional Chinese medicine (TCM) external therapies, guided by the holistic view and syndrome differentiation of TCM, employ methods such as massage and acupoint application to treat pediatric coughs. They offer significant symptom relief with few adverse reactions and are a widely used clinical treatment method. Acupoint application therapy involves mixing pulverized or ground Chinese medicinal herbs into a paste using various liquid media, applying it to acupoints or affected areas on the skin. The active ingredients penetrate the skin, stimulating acupoints and invigorating the meridians, thereby achieving the goal of treating the disease. It is a commonly used external therapy. Children's thin and delicate skin facilitates the absorption of active ingredients, making it a common treatment for common pediatric ailments such as coughs. Furthermore, children's digestive systems are not fully developed; external application reduces damage to the digestive system, liver, and kidneys, resulting in stable and significant effects with minimal side effects and high safety. Summary of the Invention

[0005] In view of the shortcomings of the existing technology, the purpose of this invention is to provide a traditional Chinese medicine patch with antitussive and antiasthmatic effects and its preparation method.

[0006] Acupoint application primarily works by stimulating the meridians with medication to unblock them, harmonize qi and blood, balance the yin and yang of the internal organs, restore bodily functions, and ultimately treat diseases. The acupoint application therapy involved in this invention is convenient to use, combining medication with acupoints to allow the active ingredients to directly reach the lesion, achieving transdermal absorption and acupoint stimulation, thereby achieving the health benefits of regulating qi, relieving cough, clearing lung heat, and calming asthma. The Tian Tu acupoint has the function of regulating qi and resolving phlegm, and absorbing lung heat. The Tan Zhong acupoint has the function of regulating the body's qi mechanism and can be used for all diseases caused by qi stagnation, such as upward reversal of lung qi, stagnation of qi and blood in the heart, and liver qi stagnation. Stimulating this acupoint can unblock the qi mechanism of the upper jiao, clear the meridians, regulate qi and disperse blood stasis; it can be used for all qi-related diseases. The combination of Tan Zhong and Tian Tu acupoints has the effect of lowering qi and calming asthma, and can treat cough and asthma. In addition, the Feishu acupoint is an important acupoint for treating lung diseases. It is mainly used to treat lung lesions and has a certain effect on improving lung function and eliminating the symptoms caused by lung dysfunction. Therefore, it has the functions of regulating qi, relieving asthma, relieving exterior symptoms and promoting lung qi circulation, and clearing lung qi. When these three acupoints are used together, they work together to promote blood circulation, clear the meridians, regulate qi, stop cough and relieve asthma.

[0007] The objective of this invention is achieved through the following technical solution: In a first aspect, the present invention provides a traditional Chinese medicine ointment comprising the following raw materials in parts by weight: 40-50 parts honeysuckle, 25-35 parts fritillaria thunbergii, 25-35 parts saposhnikovia divaricata, 40-50 parts stemona japonica, 25-35 parts monk fruit, 10-20 parts platycodon grandiflorus, 40-50 parts lepidium apetalum, 70-80 parts loquat leaf, 40-50 parts perilla frutescens, 40-50 parts coltsfoot flower, 25-35 parts licorice root, 10-20 parts frankincense, 10-20 parts myrrh, 10-20 parts rice wine, 10-20 parts aged vinegar, 30-40 parts lubricant, and 400-500 parts honey.

[0008] Preferably, the ingredients include the following parts by weight: 45 parts honeysuckle, 30 parts fritillaria thunbergii, 30 parts saposhnikovia divaricata, 45 parts stemona japonica, 30 parts monk fruit, 15 parts platycodon grandiflorus, 45 parts lepidium apetalum, 75 parts loquat leaf, 45 parts perilla frutescens, 45 parts coltsfoot flower, 30 parts licorice, 15 parts frankincense, 15 parts myrrh, 15 parts rice wine, 15 parts aged vinegar, 35 parts lubricant, and 470 parts honey.

[0009] Preferably, the ingredients include the following parts by weight: 40 parts honeysuckle, 35 parts fritillaria thunbergii, 25 parts saposhnikovia divaricata, 50 parts stemona japonica, 25 parts monk fruit, 20 parts platycodon grandiflorus, 50 parts lepidium apetalum, 80 parts loquat leaf, 40 parts perilla, 50 parts coltsfoot flower, 35 parts licorice, 10 parts frankincense, 20 parts myrrh, 10 parts rice wine, 20 parts aged vinegar, 30 parts lubricant, and 460 parts honey.

[0010] Preferably, the ingredients include the following parts by weight: 50 parts honeysuckle, 25 parts fritillaria thunbergii, 35 parts saposhnikovia divaricata, 40 parts stemona japonica, 35 parts monk fruit, 10 parts platycodon grandiflorus, 40 parts lepidium apetalum, 70 parts loquat leaf, 50 parts perilla, 40 parts coltsfoot flower, 25 parts licorice, 20 parts frankincense, 10 parts myrrh, 20 parts rice wine, 10 parts aged vinegar, 40 parts lubricant, and 480 parts honey.

[0011] Preferably, the lubricant is glycerin and sesame oil.

[0012] Preferably, the glycerin and sesame oil are present in weight parts of 10-20 parts and 20 parts, respectively.

[0013] Secondly, the present invention provides an application of traditional Chinese medicine ointment in the preparation of traditional Chinese medicine patches.

[0014] Thirdly, the present invention provides a traditional Chinese medicine patch with antitussive and antiasthmatic effects, comprising an applicator containing medical pressure-sensitive adhesive and the aforementioned traditional Chinese medicine ointment.

[0015] Fourthly, the present invention provides a method for preparing a traditional Chinese medicine patch with antitussive and antiasthmatic effects as described above, comprising the following steps: A1. Refining honey: Heat the honey to a boil, then keep it at a gentle boil to remove foam and floating wax. Then refine it for a certain period of time. Remove the refined honey from the pot and let it cool. A2. Grinding: Grind the honeysuckle, fritillaria thunbergii, saposhnikovia divaricata, stemona japonica, monk fruit, platycodon grandiflorus, lepidium seed, loquat leaf, perilla, coltsfoot flower, licorice, frankincense, and myrrh separately and then sift them. A3. Mixing and forming: Weigh out the Chinese herbal raw materials that have been crushed and sieved in step A2 according to the proportion and mix them together. While mixing, add aged vinegar and rice wine, then add refined honey and continue mixing to obtain a mixture of medicines. A4. Shaping: After the drug mixture is cooled, it is made into strips of uniform thickness, then lubricant is added and it is cut and pressed into cake-shaped Chinese medicine paste. A5. Assembly and Packaging: Assemble and package the cake-shaped herbal ointment with the applicator containing medical pressure-sensitive adhesive.

[0016] Preferably, in step A1, the refining process is carried out for a certain period of time until the material is sticky when rubbed between the fingers, but no long white threads appear when the two fingers are separated, and the relative density is 1.38~1.42.

[0017] Preferably, in step A2, the sieving is done through a 100-mesh sieve.

[0018] Preferably, in step A3, the weight of the herbal ointment for the symptoms is 1.5 to 2.5 g / piece.

[0019] Compared with the prior art, the present invention has the following beneficial effects: This invention utilizes a combination of traditional Chinese medicine ingredients—honeysuckle, fritillaria thunbergii, saposhnikovia divaricata, stemona japonica, monk fruit, platycodon grandiflorus, lepidium apetalum, loquat leaf, perilla frutescens, coltsfoot flower, licorice, frankincense, and myrrh—as the active ingredients for relieving cough and asthma. After being formulated into a herbal paste and then into a health patch, mouse experiments demonstrated its significant antitussive effect (significantly reduced cough frequency and significantly prolonged cough latency compared to the model group). Further human efficacy tests demonstrated its significant therapeutic effect on pediatric cough (wind-heat invading the lungs syndrome), with a total effective rate as high as 93.3%. It also showed significant improvement in cough symptoms (p<0.01) and other accompanying symptoms such as asthma (p<0.05) in children with constipation. Detailed Implementation

[0020] The present invention will now be described in detail with reference to specific embodiments. These embodiments will help those skilled in the art to further understand the present invention, but do not limit the invention in any way. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention. These all fall within the scope of protection of the present invention.

[0021] The terms "preferred," "more preferably," and "more suitable" used in this invention refer to embodiments of the invention that provide certain beneficial effects under certain circumstances. However, other embodiments may also be preferred under the same or other circumstances. Furthermore, the description of one or more preferred embodiments does not imply that other embodiments are unavailable, nor is it intended to exclude other embodiments from the scope of this invention.

[0022] It should be understood that, except in any operational instance or otherwise indicated, all figures representing the amounts of ingredients used, for example, in the specification and claims, should be understood to be modified in all cases by the term "about". Therefore, unless otherwise stated, the numerical parameters set forth in the following specification and appended claims are approximations varying with the desired performance to be obtained according to the invention. It is not at all an attempt to limit the application of the doctrine of equivalents to the scope of the claims; each numerical parameter should be interpreted at least according to the number of significant figures reported and by applying ordinary rounding techniques.

[0023] Although the numerical ranges and parameters illustrating the broad scope of the invention are approximate, the values ​​listed in the specific examples are reported as precisely as possible. However, any numerical value inherently contains some error that is necessarily caused by the standard deviation found in their respective test measurements.

[0024] In the following examples, all raw materials used are commercially available.

[0025] Example 1 This embodiment provides a traditional Chinese medicine patch for use on acupoints such as Tian Tu, Fei Shu, and Tan Zhong, which has the effect of relieving cough and asthma. The patch includes an applicator containing medical pressure-sensitive adhesive and a traditional Chinese medicine ointment. The ointment comprises the raw materials and their weight proportions shown in Table 1 below.

[0026] The preparation method of the herbal patch includes the following steps: A1. Honey Refining: Place the purified honey in a honey refining pot and heat it to a gentle boil (approximately 116-118°C). Maintain a gentle boil, removing any foam and floating wax. Continue refining at a gentle boil until the honey is sticky when rubbed between your fingers, but no long white threads appear when you separate your fingers, and the relative density is 1.38-1.42. Immediately remove it from the pot and transfer it to a special honey storage container to cool.

[0027] A2. Grinding: Grind the following thirteen Chinese medicinal herbs separately using a Chinese medicine grinder and pass them through a 100-mesh sieve: honeysuckle, fritillaria thunbergii, saposhnikovia divaricata, stemona japonica, monk fruit, platycodon grandiflorus, lepidium apetalum, loquat leaf, perilla frutescens, coltsfoot flower, licorice, frankincense, and myrrh.

[0028] A3. Mixing and Forming: Weigh the herbal raw material powders obtained in step A2 according to the weight proportions shown in Table 1 and place them in a mixer. While mixing, spray in aged vinegar and rice wine, and mix for 30 minutes. Then, remove the mixture and place it in a trough mixer, add the corresponding amount of refined honey obtained in step A1, and mix for 15 minutes to obtain the drug mixture.

[0029] A4. Shaping: Cool the drug mixture obtained in step A3, then add it to the feeding hopper of the strip-making machine to make strips of uniform thickness. Use glycerin and sesame oil as lubricants, cut with a knife, and press with a mold to make round cake-shaped Chinese medicine ointment of 1.8~2.0g / piece.

[0030] A5. Assembly and Packaging: Assemble and package the round, disc-shaped herbal ointment obtained in A4 with the applicator containing medical pressure-sensitive adhesive.

[0031] Example 2 This embodiment provides a traditional Chinese medicine patch for relieving cough and asthma at acupoints such as Tian Tu, Fei Shu, and Tan Zhong, comprising a patch containing medical pressure-sensitive adhesive and a traditional Chinese medicine ointment. The traditional Chinese medicine ointment comprises the raw materials and their weight proportions shown in Table 1 below.

[0032] The preparation method of the herbal patch is the same as that in Example 1.

[0033] Example 3 This embodiment provides a traditional Chinese medicine patch for relieving cough and asthma at acupoints such as Tian Tu, Fei Shu, and Tan Zhong, comprising a patch containing medical pressure-sensitive adhesive and a traditional Chinese medicine ointment. The traditional Chinese medicine ointment comprises the raw materials and their weight proportions shown in Table 1 below.

[0034] The preparation method of the herbal patch is the same as that in Example 1.

[0035] Table 1 Comparative Example 1 This comparative example provides a traditional Chinese medicine patch for relieving cough and asthma at acupoints such as Tian Tu, Fei Shu, and Tan Zhong. It includes a patch containing medical pressure-sensitive adhesive and a traditional Chinese medicine ointment. The ointment comprises the raw materials and their weight proportions shown in Table 2 below. Compared with Example 2, the only difference is that the weight proportions of honeysuckle are adjusted to 40 parts, and the weight proportions of Stemona japonica are adjusted to 60 parts.

[0036] The preparation method of the herbal patch is the same as that in Example 1.

[0037] Comparative Example 2 This comparative example provides a traditional Chinese medicine patch for relieving cough and asthma at acupoints such as Tian Tu, Fei Shu, and Tan Zhong. The patch includes an applicator containing medical pressure-sensitive adhesive and a traditional Chinese medicine ointment. The ointment comprises the raw materials and their weight proportions shown in Table 2 below. Compared to Example 2, only the addition of Lepidium apetalum is omitted, and the weight proportion of honey is 510 parts.

[0038] The preparation method of the herbal patch is the same as that in Example 1.

[0039] Comparative Example 3 This comparative example provides a traditional Chinese medicine patch for relieving cough and asthma at acupoints such as Tian Tu, Fei Shu, and Tan Zhong. The patch includes an applicator containing medical pressure-sensitive adhesive and a traditional Chinese medicine ointment. The ointment comprises the raw materials and their weight proportions shown in Table 2 below. Compared to Example 2, only myrrh is not added, and the weight proportion of honey is 480 parts.

[0040] The preparation method of the herbal patch is the same as that in Example 1.

[0041] Comparative Example 4 This comparative example provides a traditional Chinese medicine patch for relieving cough and asthma at acupoints such as Tian Tu, Fei Shu, and Tan Zhong. The patch includes a medical pressure-sensitive adhesive applicator and a traditional Chinese medicine ointment. The ointment comprises the raw materials and their weight proportions shown in Table 2 below. Compared to Example 2, only the coltsfoot flower is omitted, and the honey weight proportion is 510 parts.

[0042] The preparation method of the herbal patch is the same as that in Example 1.

[0043] Table 2 Efficacy verification test Experimental Example 1: (1) Experimental materials: Chinese herbal patches and pediatric heat-clearing and lung-ventilating plasters prepared in Examples 1-3 and Comparative Examples 1-4.

[0044] (2) Experimental animals: 90 Kunming mice, weighing between 18 and 22g, half male and half female.

[0045] (3) Experimental methods: The above-mentioned Kunming mice were randomly divided into 9 groups according to their body weight, namely, the model group, the positive control group, and 7 traditional Chinese medicine patch treatment groups, with 10 mice in each group. The mice were treated by hair removal, and 8% sodium sulfide was applied to the abdomen and back of the mice, with a hair removal area of ​​3cm×3cm. After 1 minute, the skin was washed with distilled water and the mice were fed normally for 24 hours. The model group was not treated with medication, the positive control group (the children's heat-clearing and lung-ventilating plaster was cut into 2cm×2cm pieces, one piece each for the abdomen and back), and the traditional Chinese medicine patch treatment group (the traditional Chinese medicine patches prepared in Examples 1-3 and Comparative Examples 1-4, one piece each for the abdomen and back) were administered medication continuously for 7 days. The mice were fasted for 12 hours before the last administration. After being given the test sample for 1 hour, they were placed in a glass cover with a filter paper of 0.5 mL concentrated ammonia water suspended in it to induce coughing for 30 seconds. They were then quickly removed and placed in a beaker. The signs of coughing in mice, such as abdominal muscle contraction, chest retraction, and mouth opening (with or without coughing), were observed as the standard for coughing. The number of coughs and the cough latency (s) of mice within 5 minutes were recorded.

[0046] (4) Experimental results: The number of coughs and the cough latency period of the mice were counted, and the results are shown in Table 3.

[0047] Table 3. Effects of traditional Chinese medicine patch on antitussive effect in ammonia-induced cough mice (±s, n=10) Note: Compared with the model group, **P<0.01, *P<0.05 As shown in Table 3, compared with the model group, the herbal patches prepared in Examples 1-3 significantly prolonged the cough latency period in mice (P<0.01, P<0.05, P<0.05), and the herbal patch treatment group prepared in Example 1 showed better results than the positive control group, exhibiting the best effect. Compared with the model group, the herbal patches prepared in Examples 1-3 significantly reduced the number of coughs in mice (P<0.01, P<0.05, P<0.05), and the herbal patch treatment group prepared in Example 1 again showed better results than the positive control group, exhibiting the best effect. However, compared with the model group, there were no statistically significant differences in the herbal patch treatment groups prepared in Comparative Examples 1-4 (P>0.05). Furthermore, compared with the herbal patch treatment groups prepared in Comparative Examples 1-4, the herbal patch treatment group prepared in Example 2 significantly prolonged the cough latency period and reduced the number of coughs in mice, indicating that the present invention, by adjusting the content of honeysuckle and stemona, and specifically adding lepidium seed, myrrh, and coltsfoot flower, has an enhanced antitussive effect.

[0048] Experimental Example 2: (1) Test drug: the cough-relieving and asthma-relieving Chinese herbal patch prepared in Example 1.

[0049] (2) Subjects: Children aged 1-12 years with cough due to wind-heat invading the lungs. Symptoms include: cough with sound, cough with sputum or no sputum, accompanied by chills, fever, red tongue with thin yellow coating, floating and rapid pulse or floating purple finger veins, etc.

[0050] (3) Experimental Methods: Sixty eligible subjects were randomly divided into two groups of 30 each. There were no statistically significant differences between the two groups in terms of gender, age, and course of disease. All cases presented with cough as the main symptom, accompanied by wheezing and rattling in the throat. The control group received routine anti-infective treatment and symptomatic supportive treatment such as antispasmodic, antitussive, expectorant, and antipyretic treatments based on accompanying symptoms. The treatment group received the traditional Chinese medicine patch prepared in Example 1 of this invention in addition to the treatment provided to the control group. The patch was applied to the disinfected Tian Tu, Fei Shu, and Tan Zhong acupoints, one patch per acupoint, 2-3 times daily, for 6-8 hours each time. It was important to keep the patient warm and to observe whether the patch was properly fixed after application to prevent the medication from slipping off.

[0051] (4) Observation indicators: The main observation is the time of improvement of clinical symptoms, including the time of disappearance of cough, the time of return of body temperature to normal, and the time of relief of other accompanying symptoms.

[0052] (5) Efficacy criteria: Refer to the "Standards for Diagnosis and Efficacy of Diseases and Syndromes in Traditional Chinese Medicine". Cured: Cough and other clinical symptoms and signs disappear, and body temperature returns to normal. Effective: Cough and other clinical symptoms and signs are significantly relieved, and body temperature decreases. Ineffective: Cough and other clinical symptoms and signs do not improve, or even worsen.

[0053] (6) Experimental results: Before treatment, patients in the treatment group and the control group were compared. There were no significant differences between the two groups in terms of age, disease duration, severity of illness, and symptoms of abdominal distension and pain. The results of the treatment group and the control group after treatment are shown in Tables 4 and 5.

[0054] Table 4 Comparison of symptom improvement between the two groups Table 5 Comparison of clinical efficacy between the two groups As can be seen from the results in Tables 4 and 5, the herbal patch prepared in this invention (treatment group) has a significant therapeutic effect on pediatric cough (wind-heat invading the lungs syndrome), with a total effective rate of up to 93.3%. It significantly improves the cough symptoms (p<0.01) and other accompanying symptoms such as wheezing (p<0.05) in children with constipation, and the effect is better than that of the control group. Furthermore, no serious adverse events were found in the experiment.

[0055] Typical case: 1. Ms. Wang, female, 4 years old, had a cold a week prior, presenting with symptoms such as runny nose, cough, fever, and nasal congestion. She had taken oral antibiotics and traditional Chinese medicine for 5 days. The fever subsided, but the cough worsened, producing phlegm that was difficult to expectorate, accompanied by rattling sounds in the throat. She also experienced poor sleep, frequently waking up coughing, poor appetite, a pale red tongue with a thin, yellow, greasy coating, and a wiry, slippery pulse. The cough-relieving and asthma-relieving traditional Chinese medicine patch prepared in Example 1 was applied to the sterilized Tian Tu (CV22), Fei Shu (BL13), and Tan Zhong (CV17) acupoints, one patch per acupoint, twice daily. After 3 days of use, the cough significantly improved; she no longer coughed at night, only coughed slightly during activity, and there was no rattling sound in the throat. Her appetite increased. After 5 days of use, she was cured.

[0056] 2. Zhao, male, 7 years old, presented with fever and cough for 2 days due to an external pathogenic factor. After taking ibuprofen oral solution, the fever subsided, but he developed a cough, paroxysmal cough, with phlegm that was difficult to expectorate, sore throat, snoring, no nasal congestion or runny nose, poor appetite, and normal sleep. His tongue was red with a thick, yellowish coating, and his pulse was thready and rapid. The cough-relieving and asthma-relieving herbal patches prepared in Example 2 were applied to the sterilized Tian Tu (CV22), Fei Shu (BL13), and Tan Zhong (CV17) acupoints, one patch per acupoint, twice daily. After 4 days of use, he experienced occasional cough, easily expectorated yellow phlegm, improved appetite, and restful sleep. After 7 days of use, he was cured.

[0057] 3. Mr. Li, male, 6 years old. The child began to have a fever and a slight cough 3 days ago. He had taken ibuprofen oral solution and children's cold medicine. The fever subsided after 2 days, but the cough worsened. He was treated with cough syrup and other medications, but the cough did not decrease. The cough was worse at night, making it difficult to sleep. After coughing, he had a dry mouth, did not like to drink, had a rough voice and was irritable. His appetite was poor. His tongue was reddish with a thick, greasy, slightly yellow coating, and his pulse was rapid. The cough-relieving and asthma-relieving Chinese herbal patches prepared in Example 3 were applied to the disinfected Tian Tu, Fei Shu, and Tan Zhong acupoints, one patch per acupoint, twice a day. After 4 days of use, the patient's spirits improved, the cough was significantly reduced, and he slept soundly at night with only occasional coughing. After 7 days of use, he was cured.

[0058] This invention has many specific applications, and the above description is only a preferred embodiment. It should be noted that the above embodiments are for illustrative purposes only and are not intended to limit the scope of protection of this invention. For those skilled in the art, several improvements can be made without departing from the principle of this invention, and these improvements should also be considered within the scope of protection of this invention.

Claims

1. A traditional Chinese medicine ointment for relieving cough and asthma, characterized in that, Made from the following ingredients in parts by weight: honeysuckle 40-50 parts, fritillaria thunbergii 25-35 parts, saposhnikovia divaricata 25-35 parts, stemona japonica 40-50 parts, monk fruit 25-35 parts, platycodon grandiflorus 10-20 parts, lepidium apetalum 40-50 parts, loquat leaf 70-80 parts, perilla 40-50 parts, coltsfoot flower 40-50 parts, licorice root 25-35 parts, frankincense 10-20 parts, myrrh 10-20 parts, rice wine 10-20 parts, aged vinegar 10-20 parts, lubricant 30-40 parts, honey 400-500 parts; The lubricant is glycerin and sesame oil.

2. The herbal ointment for relieving cough and asthma according to claim 1, characterized in that, Made from the following ingredients in parts by weight: honeysuckle 45 parts, fritillaria thunbergii 30 parts, saposhnikovia divaricata 30 parts, stemona japonica 45 parts, monk fruit 30 parts, platycodon grandiflorus 15 parts, lepidium apetalum 45 parts, loquat leaf 75 parts, perilla 45 parts, coltsfoot flower 45 parts, licorice 30 parts, frankincense 15 parts, myrrh 15 parts, rice wine 15 parts, aged vinegar 15 parts, lubricant 35 parts, honey 470 parts.

3. The herbal ointment for relieving cough and asthma according to claim 1, characterized in that, Made from the following ingredients in parts by weight: honeysuckle 40 parts, fritillaria thunbergii 35 parts, saposhnikovia divaricata 25 parts, stemona japonica 50 parts, monk fruit 25 parts, platycodon grandiflorus 20 parts, lepidium apetalum 50 parts, loquat leaf 80 parts, perilla 40 parts, coltsfoot flower 50 parts, licorice 35 parts, frankincense 10 parts, myrrh 20 parts, rice wine 10 parts, aged vinegar 20 parts, lubricant 30 parts, and honey 460 parts.

4. The herbal ointment for relieving cough and asthma according to claim 1, characterized in that, The ingredients include the following parts by weight: honeysuckle 50 parts, fritillaria thunbergii 25 parts, saposhnikovia divaricata 35 parts, stemona japonica 40 parts, monk fruit 35 parts, platycodon grandiflorus 10 parts, lepidium apetalum 40 parts, loquat leaf 70 parts, perilla 50 parts, coltsfoot flower 40 parts, licorice 25 parts, frankincense 20 parts, myrrh 10 parts, rice wine 20 parts, aged vinegar 10 parts, lubricant 40 parts, and honey 480 parts.

5. The application of a traditional Chinese medicine ointment for relieving cough and asthma according to any one of claims 1-4 in the preparation of traditional Chinese medicine patches.

6. A traditional Chinese medicine patch with antitussive and antiasthmatic effects, characterized in that, It includes an applicator containing medical pressure-sensitive adhesive and the traditional Chinese medicine ointment as described in any one of claims 1-4.

7. A method for preparing a traditional Chinese medicine patch with antitussive and antiasthmatic effects according to claim 6, characterized in that, Includes the following steps: A1. Refining honey: Heat the honey to a boil, then keep it at a gentle boil to remove foam and floating wax. Then refine it for a certain period of time. Remove the refined honey from the pot and let it cool. A2. Grinding: Grind the honeysuckle, fritillaria thunbergii, saposhnikovia divaricata, stemona japonica, monk fruit, platycodon grandiflorus, lepidium seed, loquat leaf, perilla, coltsfoot flower, licorice, frankincense, and myrrh separately and then sieve them; A3. Mixing and forming: Weigh out the Chinese herbal raw materials that have been crushed and sieved in step A2 according to the proportion and mix them together. While mixing, add aged vinegar and rice wine, then add refined honey and continue mixing to obtain a mixture of medicines. A4. Shaping: After the drug mixture is cooled, it is made into strips of uniform thickness, then lubricant is added and it is cut and pressed into cake-shaped Chinese medicine paste. A5. Assembly and Packaging: Assemble and package the cake-shaped herbal ointment with the applicator containing medical pressure-sensitive adhesive.

8. The method for preparing the herbal patch with antitussive and antiasthmatic effects according to claim 7, characterized in that, In step A2, the sieving is done through a 100-mesh sieve.

9. The method for preparing the traditional Chinese medicine patch with antitussive and antiasthmatic effects according to claim 7, characterized in that, In step A3, the weight of the cake-shaped traditional Chinese medicine paste is 1.5 to 2.5 g / piece.

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