Non-invasive flexible blood glucose sensing and sleep monitoring device

Abstract

The present application provides a non-invasive flexible blood glucose detection and sleep monitoring device for monitoring the sleep state and blood glucose state of a detected person. The non-invasive flexible blood glucose detection and sleep monitoring device comprises a detection module including a substrate, a plurality of optical modules including optical cover plates with a coating layer, a barrier wall disposed on the substrate, the barrier wall establishing a first space and a second space with the substrate and the optical modules, respectively, a light emitting unit disposed in the first space, a sensing unit disposed in the second space, and a flexible piezoelectric module for being disposed on the detected person, and a detection unit connected to the detection module and the flexible piezoelectric module.

Description

Technical Field

[0001] This invention is applied in the fields of sleep monitoring and blood glucose detection in biomedical technology, and in particular, it is a non-invasive, flexible blood glucose detection and sleep monitoring device for monitoring the sleep and blood glucose status of a subject. Background Technology

[0002] Traditionally, flexible piezoelectric film devices are mostly used in sleep monitoring devices, and rarely have non-invasive blood glucose detection functions.

[0003] A sleep monitoring device disclosed in US Patent Publication No. US20210038092A1 includes a layered sensor comprising at least one substrate layer comprising a plurality of laterally adjacent substrates. The substrate layer can be formed by interleaving the fingers of a first sheet with the fingers of a second sheet. Combining multiple substrates in a single layer of the layered sensor allows for the integration of various materials and / or sensing mechanisms within that single layer; however, it only provides sleep monitoring capabilities and does not possess non-invasive methods for observing bodily conditions, such as blood glucose monitoring.

[0004] In view of this, the present invention provides a non-invasive, flexible blood glucose detection and sleep monitoring device, which modifies the outermost layer design of known technologies by embedding a non-invasive blood glucose detection module after interlacing (setting) an array or random blind holes in the protective layer and adhesive layer above the electrode layer. This expands the scope of application of known technologies. Summary of the Invention

[0005] The primary objective of this invention is to provide a non-invasive, flexible blood glucose detection and sleep monitoring device for monitoring the sleep and blood glucose status of the subject.

[0006] To achieve the above or other objectives, the present invention provides a non-invasive flexible blood glucose detection and sleep monitoring device for monitoring the sleep and blood glucose status of a subject. The non-invasive flexible blood glucose detection and sleep monitoring device includes: a detection module comprising: a substrate; multiple optical modules, including an optical cover plate with a coating layer; a barrier wall disposed on the substrate, the barrier wall establishing a first space and a second space respectively through the substrate and the optical modules; a light-emitting unit disposed in the first space, the light-emitting unit generating a first light ray emitted towards the subject; and a sensing unit disposed in the second space, the sensing unit receiving a second light ray from the subject, and the sensing unit generating a corresponding first signal based on the second light ray. The system includes: a second light source, which is a reflected light source of the first light source; and a flexible piezoelectric module, which is disposed on the object being detected. The flexible piezoelectric module includes: a first protective layer with a first blind hole for housing the detection module; a first electrode layer electrically connected to the substrate and receiving a first signal; a second electrode layer; and a first piezoelectric layer disposed between one side of the first electrode layer and one side of the second electrode layer. After being subjected to an external force, the first piezoelectric layer induces a piezoelectric effect, generating a second signal between the first electrode layer and the second electrode layer; a second protective layer disposed on the other side of the second electrode layer; and a detection unit connected to the detection module and the flexible piezoelectric module, which receives the first signal and the second signal.

[0007] Furthermore, the flexible piezoelectric module also includes a support layer, one side of which is disposed on one side of the second electrode layer.

[0008] Furthermore, the flexible piezoelectric module also includes a grounding layer, which is located on the other side of the support layer.

[0009] Furthermore, the flexible piezoelectric module also includes an adhesive layer, which is selectively disposed on one side of the first protective layer, one side of the second protective layer, one side of the second electrode layer, one side of the support layer, and one side of the grounding layer.

[0010] Furthermore, the flexible piezoelectric module also includes a third electrode layer, a fourth electrode layer, and a second piezoelectric layer. The third electrode layer is disposed on the other side of the support layer, the fourth electrode layer is disposed on one side of the second protective layer, and the second piezoelectric layer is disposed between the third electrode layer and the fourth electrode layer. After being subjected to external force, the second piezoelectric layer induces a piezoelectric effect, generating a third signal between the third electrode layer and the fourth electrode layer, and the third signal is transmitted to the detection unit.

[0011] Furthermore, the second protective layer has a second blind hole, which is used to set another detection module.

[0012] Furthermore, the substrate of another detection module is electrically connected to the third electrode layer.

[0013] Furthermore, the number of second blind holes is greater than the number of other detection modules, and the number of second blind holes is not less than the number of other detection modules.

[0014] Furthermore, the number of first blind holes is greater than the number of detection modules, and the number of first blind holes is not less than the number of detection modules.

[0015] Furthermore, the arrangement of the first blind hole and the second blind hole can be either regular or arbitrary.

[0016] Compared to known technologies, the present invention provides a non-invasive, flexible blood glucose detection and sleep monitoring device that can not only collect and analyze the sleep patterns of the subject, but also detect changes in blood glucose levels during sleep, and its flexibility increases its ease of use. Attached Figure Description

[0017] Figure 1a This is a layered structure diagram of the detection module according to the first embodiment of the present invention.

[0018] Figure 1b This is a layered structure diagram of the flexible piezoelectric module according to the first embodiment of the present invention.

[0019] Figure 1c This is a layered structural diagram of a non-invasive flexible blood glucose detection and sleep monitoring device according to the first embodiment of the present invention.

[0020] Figure 2a This is a layered structure diagram of the flexible piezoelectric module according to the second embodiment of the present invention.

[0021] Figure 2b This is a layered structural diagram of a non-invasive flexible blood glucose detection and sleep monitoring device according to a second embodiment of the present invention.

[0022] Figure 3a This is a layered structural diagram of a non-invasive flexible blood glucose detection and sleep monitoring device according to the third embodiment of the present invention.

[0023] Figure 3b This is another layered structural diagram of the non-invasive flexible blood glucose detection and sleep monitoring device according to the third embodiment of the present invention.

[0024] Figure 4 This is a schematic diagram of the arrangement of the detection modules according to any embodiment of the present invention. Detailed Implementation

[0025] To fully understand the purpose, features, and effects of the present invention, the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments:

[0026] In this invention, the terms "a" or "an (kind)" are used to describe the units, elements, and components described herein. This is done for ease of explanation only and to provide a general meaning regarding the scope of the invention. Therefore, unless it is clearly intended otherwise, this description should be understood to include one, at least one, and the singular also includes the plural.

[0027] In this document, the terms “comprising,” “including,” “having,” “containing,” or any other similar terms are intended to cover non-exclusive inclusions. For example, an element, structure, article of manufacture, or apparatus containing a plural element is not limited to those listed herein, but may include other elements not expressly listed but which are typically inherent to that element, structure, article of manufacture, or apparatus. Furthermore, unless expressly stated to the contrary, the term “or” is a general “or,” not an exclusive “or.”

[0028] refer to Figures 1a to 1c , Figures 1a to 1c This is a schematic diagram of a non-invasive flexible blood glucose detection and sleep monitoring device according to a first embodiment of the present invention, used to monitor the sleep state and blood glucose state of a subject. The non-invasive flexible blood glucose detection and sleep monitoring device includes: a detection module, including: a substrate 1; multiple optical modules 2, including an optical cover plate 220 with a coating layer 210; a barrier 230 disposed on the substrate 1, the barrier 230 establishing a first space 231 and a second space 232 respectively through the substrate 1 and the optical modules 2; a light-emitting unit 240 disposed in the first space 231, the light-emitting unit 240 generating a first light ray that is emitted towards the subject; and a sensing unit 250 disposed in the second space 232, the sensing unit 250 receiving a second light ray from the subject, and the sensing unit 250 generating a corresponding first signal based on the second light ray, wherein the second light ray is a first The light source includes: reflected light; and a flexible piezoelectric module 3 for mounting on (or in contact with) the object being detected. The flexible piezoelectric module 3 includes: a first protective layer 311 with a first blind hole 351 for mounting the detection module 2; a first electrode layer 321 electrically connected to the substrate 1 and receiving a first signal; a second electrode layer 322; and a first piezoelectric layer 331 disposed between one side of the first electrode layer 321 and one side of the second electrode layer 322. After being subjected to an external force, the first piezoelectric layer 331 induces a piezoelectric effect, generating a second signal between the first electrode layer 321 and the second electrode layer 322; a second protective layer 312 disposed on the other side of the second electrode layer 322; and a detection unit 4 connected to the detection module 2 and the flexible piezoelectric module 3, which receives the first and second signals.

[0029] Furthermore, the flexible piezoelectric module 3 also includes: a support layer 37, one side of which is disposed on one side of the second electrode layer 322; a ground layer 38, disposed on the other side of the support layer 37; and an adhesive layer 36, selectively disposed on one side of the first protective layer 311, one side of the second protective layer 312, one side of the second electrode layer 322, one side of the support layer 37, and one side of the ground layer 38.

[0030] refer to Figure 2a and Figure 2b , Figure 2a and Figure 2b This is a schematic diagram of a non-invasive flexible blood glucose detection and sleep monitoring device according to a second embodiment of the present invention. The flexible piezoelectric module 3 further includes a third electrode layer 323, a fourth electrode layer 324, and a second piezoelectric layer 332. The third electrode layer 323 is disposed on the other side of the support layer 37, the fourth electrode layer 324 is disposed on one side of the second protective layer 312, and the second piezoelectric layer 332 is disposed between the third electrode layer 323 and the fourth electrode layer 324. After being subjected to an external force, the second piezoelectric layer 332 induces a piezoelectric effect, generating a third signal between the third electrode layer 323 and the fourth electrode layer 324. The third signal is transmitted to the detection unit 4. The second protective layer 312 has a second blind hole 352, which is used to house another detection module 2. The substrate of the other detection module is electrically connected to the fourth electrode layer 324.

[0031] refer to Figure 3a and Figure 3b , Figure 3a and Figure 3b This is a schematic diagram of a non-invasive flexible blood glucose detection and sleep monitoring device according to a third embodiment of the present invention. Figure 3a This is a layered structural diagram of the non-invasive flexible blood glucose detection and sleep monitoring device according to the third embodiment of the present invention. Figure 3b This is another layered structural diagram of the non-invasive flexible blood glucose detection and sleep monitoring device according to the third embodiment of the present invention.

[0032] The flexible piezoelectric module 3 further includes a third electrode layer 323, a fourth electrode layer 324, and a second piezoelectric layer 332. The third electrode layer 323 is disposed on the other side of the support layer 37, the fourth electrode layer 324 is disposed on one side of the second protective layer 312, and the second piezoelectric layer 332 is disposed between the third electrode layer 323 and the fourth electrode layer 324. After being subjected to an external force, the second piezoelectric layer 332 induces a piezoelectric effect, generating a third signal between the third electrode layer 323 and the fourth electrode layer 324. The third signal is transmitted to the detection unit 4, and the detection module 2 is disposed in the first blind hole 351 formed in the first protective layer 311 or in the second blind hole 352 formed in the second protective layer 312, depending on the desired direction.

[0033] Furthermore, the number of second blind holes 352 is greater than the number of other detection modules 2, and the number of second blind holes 352 is not less than the number of other detection modules 2; the number of first blind holes 351 is greater than the number of detection modules 2, and the number of first blind holes 351 is not less than the number of detection modules 2.

[0034] refer to Figure 4 , Figure 4 This is a schematic diagram of the arrangement of the detection module according to an embodiment of the present invention, wherein the first blind hole 351 and the second blind hole 352 are arranged in a regular or arbitrary manner.

[0035] The present invention has been disclosed above with reference to preferred embodiments. However, those skilled in the art should understand that these embodiments are for illustrative purposes only and should not be construed as limiting the scope of the invention. It should be noted that, for example, equivalent variations and substitutions to these embodiments should be included within the scope of the present invention. Therefore, the scope of protection of the present invention should be determined by the claims.

[0036] [Symbol Explanation]

[0037] 1...Substrate

[0038] 2…Optical Module

[0039] 210…coating layer

[0040] 220… Optical cover plate

[0041] 230… retaining wall

[0042] 231…First Space

[0043] 232…Second Space

[0044] 240…light-emitting units

[0045] 250…sensing units

[0046] 3… Flexible piezoelectric module

[0047] 311…First protective layer

[0048] 312…Second protective layer

[0049] 321…First Electrode Layer

[0050] 322…Second Electrode Layer

[0051] 323…Third electrode layer

[0052] 324…Fourth electrode layer

[0053] 331…First piezoelectric layer

[0054] 332…Second piezoelectric layer

[0055] 351…First blind hole

[0056] 352…Second blind hole

[0057] 36… Adhesive layer

[0058] 37… Support layer

[0059] 38…grounding layer

[0060] 4… Detection Unit

Claims

1. A non-invasive, flexible blood glucose detection and sleep monitoring device for monitoring the sleep and blood glucose status of a subject, the non-invasive, flexible blood glucose detection and sleep monitoring device comprising: The detection module includes: substrate; Multiple optical modules, including an optical cover plate with a coating layer; A barrier is set on the substrate, and the barrier establishes a first space and a second space respectively through the substrate and the optical module; A light-emitting unit is disposed in the first space, the light-emitting unit generates a first ray of light and the first ray of light is emitted toward the detected object; A sensing unit, disposed in the second space, receives a second light ray from the detected object and generates a corresponding first signal based on the second light ray, wherein the second light ray is the reflected light of the first light ray; and A flexible piezoelectric module for mounting on the subject being detected, the flexible piezoelectric module comprising: The first protective layer has a first blind hole, which is used to set up the detection module. The first electrode layer is electrically connected to the substrate and receives the first signal; Second electrode layer; and A first piezoelectric layer is disposed between one side of the first electrode layer and one side of the second electrode layer. After being subjected to an external force, the first piezoelectric layer induces a piezoelectric effect and generates a second signal between the first electrode layer and the second electrode layer. The second protective layer is disposed on the other side of the second electrode layer; The detection unit is connected to the detection module and the flexible piezoelectric module. The detection unit receives the first signal and the second signal.

2. The non-invasive flexible blood glucose detection and sleep monitoring device according to claim 1, wherein, The flexible piezoelectric module also includes a support layer, one side of which is disposed on one side of the second electrode layer.

3. The non-invasive flexible blood glucose detection and sleep monitoring device according to claim 2, wherein, The flexible piezoelectric module also includes a grounding layer, which is located on the other side of the support layer.

4. The non-invasive flexible blood glucose detection and sleep monitoring device according to claim 2, wherein, The flexible piezoelectric module also includes an adhesive layer, which is selectively disposed on one side of the first protective layer, one side of the second protective layer, one side of the second electrode layer, one side of the support layer, and one side of the grounding layer.

5. The non-invasive, flexible blood glucose detection and sleep monitoring device according to claim 1 or 2, wherein, The flexible piezoelectric module also includes a third electrode layer, a fourth electrode layer and a second piezoelectric layer. The third electrode layer is disposed on the other side of the support layer, the fourth electrode layer is disposed on one side of the second protective layer, and the second piezoelectric layer is disposed between the third electrode layer and the fourth electrode layer. After the second piezoelectric layer is subjected to external force, the piezoelectric effect is triggered in the second piezoelectric layer, thereby generating a third signal between the third electrode layer and the fourth electrode layer, and the third signal is transmitted to the detection unit.

6. The non-invasive, flexible blood glucose detection and sleep monitoring device according to claim 5, wherein, The second protective layer has a second blind hole, which is used to set up another detection module.

7. The non-invasive flexible blood glucose detection and sleep monitoring device according to claim 6, wherein, The substrate of the other detection module is electrically connected to the fourth electrode layer.

8. The non-invasive flexible blood glucose detection and sleep monitoring device according to claim 6, wherein, The number of second blind holes is greater than the number of the other detection modules, and the number of second blind holes is not less than the number of the other detection modules.

9. The non-invasive flexible blood glucose detection and sleep monitoring device according to claim 1, wherein, The number of first blind holes is greater than the number of detection modules, and the number of first blind holes is not less than the number of detection modules.

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