Transparent serum oil system based on white pool seed oil

CN117982373BActive Publication Date: 2026-09-29SHANGHAI JAHWA UNITED
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Patent Information

Application Number
CN202410054202.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-01-15
Publication Date
2026-09-29
Estimated Expiration
2044-01-15

AI Technical Summary

Technical Problem

但是,不饱和脂肪酸结构不稳定,因此在加热、在空气中或与氧气接触时,容易氧化变质,当在化妆品中使用植物油脂时,往往需要额外添加抗氧化剂以帮助产品的货架期稳定性

Benefits of technology

[0036]本发明意外地发现,油醇聚醚-3磷酸酯和水溶性化妆品原料在一定比例下(如6:1至10:1范围内,优选为8:1至10:1范围内)可以在白池花籽油中实现增溶,将增溶后的组合物加入含白池花籽油的精华油后,精华油仍然能够保持透明外观且不变。

✦ Generated by Eureka AI based on patent content.

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Abstract

The present application provides a transparent serum oil system based on white pool seed oil, the system comprises white pool seed oil, emulsifying solubilizer and water-soluble efficacy raw materials, wherein the content of the white pool seed oil is at least 50wt% based on the total weight of the system, and the weight ratio of the emulsifying solubilizer and the water-soluble efficacy raw materials is at least 6:1. And a serum oil with uniform and consistent transparent appearance, which comprises 0-100wt% of a transparent serum oil system based on white pool seed oil.
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Description

Technical Field

[0001] This invention belongs to the field of cosmetic technology and relates to an essential oil system that can be used with meadowfoam seed oil as the main oil, and more specifically to an essential oil system composition containing water-soluble active ingredients and with meadowfoam seed oil as the main oil. Background Technology

[0002] With the rise of the "oil-based skincare" trend, more and more oil-based skincare products have appeared on the market in recent years, especially in the essential oil category, where market competition among major beauty brands has become increasingly fierce.

[0003] Because skin is naturally both lipophilic and oil-based, oil-based products penetrate the skin more easily than water-based products. They also carry beneficial ingredients more quickly, allowing them to work more effectively. Therefore, the principle of "oil-based skincare" is to replenish the skin's lipids, helping to form a sebum film on the skin's surface, thus preventing moisture loss and better retaining hydration. Simultaneously, it helps resist changes in the external environment, maintaining the skin barrier and microecological balance, protecting the skin from the influence of external bacteria, and greatly contributing to skin stability. Therefore, facial oil products are often among the key functional products promoted by major brands.

[0004] Looking at the domestic essential oil market, from a formulation technology perspective, it can be mainly divided into three categories: The first category is pure oil-based essential oils, such as Lin Qingxuan Camellia Repairing Essential Oil and Lan Time Oil; the second category is special essential oils with suspended oil droplets, such as Lan Ningguang Yuehuo Essence Oil and Quadi Suspended Oil Ampoules; the third category is dual-layer essential oils with oil and water layers, such as PMPM Rose Squalane Essential Oil, etc. These different types of essential oils have differentiated effects and user experiences, meeting the diverse skincare needs of different consumers for "oil-based skincare," especially the latter two types, which have a more refreshing feel and are popular among younger consumers. However, after analyzing the formulations of the above essential oils, we found that the reason why the latter two types of essential oils have a refreshing feel is because a large part of their formulation is water or water-based ingredients. In essence, they are not actually true essential oils, but rather innovative serum formulations, water-oil-based serum products that have emerged due to the market trend of "oil-based skincare."

[0005] True pure oil-based serums are usually made up of one or more compatible oils, presenting a uniform and transparent appearance. However, since oil and water are immiscible, it is generally difficult to add water-soluble ingredients to these serums. This greatly limits the use of some water-soluble active ingredients with skincare benefits in the serum category.

[0006] Cosmetic oils can be classified by source into mineral oils, vegetable oils, animal oils, and synthetic esters. Vegetable oils are primarily composed of fatty acid glycerides, containing a large amount of unsaturated fatty acids, which can help lower blood cholesterol levels and prevent cardiovascular disease. However, unsaturated fatty acids are structurally unstable and easily oxidize and deteriorate when heated, exposed to air, or contact with oxygen. Therefore, when using vegetable oils in cosmetics, antioxidants are often added to help maintain product shelf-life stability. Meadowfoam seed oil has a high content of long-chain fatty acids (over 98%) and a relatively low content of linoleic acid, thus exhibiting extremely strong antioxidant activity. The oxidative stability of meadowfoam seed oil is more than 10 times that of jojoba oil, making it one of the most stable vegetable oils. Studies have shown that meadowfoam seed oil has antioxidant and skin barrier repair effects and is widely used in cosmetics, especially in essential oil products.

[0007] Oleyl alcohol polyether-3 phosphate is an O / W oil-in-water emulsifier that is frequently used as a surfactant in cosmetics. In the cosmetics industry, the highest historical usage of oleyl alcohol polyether-3 phosphate in leave-on products is regulated to be no more than 7.5%, while there is currently no upper limit for rinse-off products.

[0008] Structural formula of oleyl alcohol polyether-3-phosphate

[0009] For example, Chinese patent CN109044857B (application number 201811122564.7) combines oleyl alcohol polyether-3 phosphate with alkylamidopropyl dimethylamine and polyglycerol ester emulsifiers to invent a silicone-free shampoo conditioning agent composition. This composition, used in shampoos, provides hair with good combability, anti-tangling, anti-static properties, and shine. Oleyl alcohol polyether-3 phosphate can also be combined with other emulsifiers containing PEG or PPG structures to prepare microemulsion systems. For instance, Chinese patent CN110934795A (application number 201911328646.1) combines oleyl alcohol polyether-3 phosphate and PPG-5-cetyl alcohol polyether-20 in a certain proportion to carry meadowfoam seed oil, water, and other additives, forming a microemulsion essence with better stratum corneum penetration and efficacy.

[0010] Currently, no similar technology has been found to use oleyl alcohol polyether-3 phosphate to solubilize water-soluble raw materials in oil-based systems, therefore, this invention has a certain degree of technical innovation.

[0011] The present invention unexpectedly discovered that oleyl alcohol polyether-3 phosphate and water-soluble cosmetic raw materials can be solubilized in meadowfoam seed oil in a certain ratio (such as 6:1 to 10:1, preferably 8:1 to 10:1). When the solubilized composition is added to an essential oil containing meadowfoam seed oil, the essential oil can still maintain its transparent appearance and remain unchanged.

[0012] This invention provides a composition containing oleyl alcohol polyether-3-phosphate and water-soluble active ingredients. Taking meadowfoam seed oil as an example, this composition can be used not only in systems where meadowfoam seed oil is the single oil, but also in essential oil systems where meadowfoam seed oil is the main oil and contains other mixed oils, so that the essential oil still maintains a transparent appearance. This solves the technical problem of applying water-soluble active ingredients to essential oils. Summary of the Invention

[0013] The purpose of this invention is to provide a composition containing water-soluble active ingredients that can be used in an essential oil system with meadowfoam seed oil as the main oil.

[0014] This invention provides a transparent essential oil system based on meadowfoam seed oil, the system comprising meadowfoam seed oil, emulsifying solubilizer and water-soluble active ingredients, wherein, based on the total weight of the system, the content of meadowfoam seed oil is at least 50 wt%, and the weight ratio of the emulsifying solubilizer to the water-soluble active ingredients is at least 6:1.

[0015] In a preferred embodiment, the weight ratio of the emulsifying solubilizer to the water-soluble functional ingredient is 6:1 to 10:1.

[0016] Preferably, the weight ratio of the emulsifying solubilizer to the water-soluble functional ingredient is 6:1 to 8:1.

[0017] In a preferred embodiment, the content of meadowfoam seed oil is 50-99.99 wt%.

[0018] Preferably, the content of meadowfoam seed oil is 59.32-99.4 wt%.

[0019] In a preferred embodiment, the emulsifying solubilizer is an oil-soluble amphiphilic surfactant with an HLB value of 5-12, and the emulsifying solubilizer is selected from at least one of oleyl alcohol polyether-3 phosphate, polyglycerol-3 polyricinoleate, and lauryl alcohol polyether-4.

[0020] In a preferred embodiment, the emulsifying solubilizer is oleyl alcohol polyether-3 phosphate.

[0021] In a preferred embodiment, the water-soluble active ingredient is selected from: plant extracts with a solid content ≥1wt%, water-soluble polypeptides with a polypeptide content ≥50ppm, fermentation broth and fermentation products with a solid content ≥0.9wt%, and at least one of other water-soluble vitamins, amino acids, sugars or polysaccharides.

[0022] In a preferred embodiment, the solid content of the plant extract is 1-7.5 wt%.

[0023] Preferably, the solid content of the plant extract is 1.4-7.5 wt%.

[0024] The plant extracts are selected from at least one of the following: Lindera strychnifolia, Portulaca oleracea, Lotus, Ginseng, Ganoderma lucidum, Artemisia annua, Polygonatum sibiricum, Astragalus membranaceus, Scutellaria baicalensis, Poria cocos, Paeonia lactiflora, Paeonia suffruticosa, Saussurea involucrata, Tuberculum truncata, Dendrobium nobile, Ginkgo biloba, Lycium barbarum, Perilla frutescens, Ganoderma lucidum, Hippophae rhamnoides, Ligusticum chuanxiong, Angelica sinensis, Polygonum multiflorum, Rehmannia glutinosa, Leonurus japonicus, Salvia miltiorrhiza, Epiphyllum oxypetalum, Osmanthus fragrans, Magnolia officinalis, Cherry blossom, Centella asiatica, Oat, Dioscorea opposita, Polygonatum odoratum, Orchid, Glycyrrhiza uralensis, Aloe vera, Fig, Peppermint, Atractylodes lancea, Artemisia argyi, Cedarwood, Sequoia glyptostroboides, Witch hazel, Lupinus oleracea, Pea, Schisandra chinensis, Sapindus mukorossi, Cuscuta chinensis, Cistanche deserticola, Nutmeg, Sesame, Ophiopogon japonicus, Tea, Carrot, Papaya, Coconut, Grape, Lemon, Cactus, Gynostemma pentaphyllum, Rhodiola rosea, etc., from the roots / stems / branches / leaves / flowers / seeds / kernels / barks / whole plants, etc.

[0025] In a preferred embodiment, the solid content of the fermentation broth and fermentation products is 0.9-5 wt%.

[0026] Preferably, the solid content of the fermentation broth and fermentation products is 1.5-3.0 wt%.

[0027] The fermentation broth and fermentation products are selected from: Bifida ferment lysate, Bifida ferment filtrate, Bifida ferment extract, rice ferment filtrate, Fermentosoma ferment extract, Galactomyces ferment filtrate, red yeast rice / rice fermentation product, Pseudomonas aeruginosa ferment extract, Alternaria aeruginosa ferment extract, yeast ferment extract, yeast / soybean protein fermentation product, yeast / rice ferment filtrate, yeast fermentation product, yeast ferment filtrate, yeast ferment lysate filtrate, yeast / Acetobacter xylinum / black tea fermentation product, and Lactobacillus. At least one of the following: soybean fermentation product extract, Lactobacillus / soybean extract fermentation product filtrate, Lactobacillus / rice fermentation product, Lactobacillus / soy milk fermentation product filtrate, Lactobacillus fermentation product, Lactobacillus fermentation lysate, Lactobacillus / milk fermentation lysate, Lactobacillus fermentation product, Lactobacillus fermentation lysate, Lactobacillus fermentation extract, Streptococcus thermophilus fermentation product, Thermophilus thermophilus fermentation product, Oscillatoria hygroscopica fermentation product, Bacillus / soybean fermentation product extract, Bacillus / glutamate fermentation product filtrate, Bacillus / rice bran extract / soybean extract fermentation product filtrate, and Bacillus fermentation product.

[0028] In a preferred embodiment, the water-soluble polypeptide contains ≥100 ppm of polypeptide.

[0029] Preferably, the water-soluble polypeptides contain 350 ppm to 20000 ppm of polypeptides.

[0030] The water-soluble polypeptides are selected from anti-wrinkle polypeptides, soybean polypeptides, wheat polypeptides, oat polypeptides, wild soybean polypeptides, glutathione, dipeptide diaminobutyryl benzylamide diacetate, carnosine, yeast polypeptides, alanine / histidine / lysine polypeptide copper hydrochloride, arginine / lysine polypeptides, dipeptide-1, dipeptide-2, dipeptide-4, dipeptide-15, oligopeptide-1, oligopeptide-2, oligopeptide-29, oligopeptide-3, oligopeptide-32, oligopeptide-4, oligopeptide-5, oligopeptide-6, nonapeptide-1, hexapeptide-1, hexapeptide-11, hexapeptide-2, hexapeptide-3, hexapeptide-5, hexapeptide-9, heptapeptide-6, myristoyl hexapeptide-5, myristoyl pentapeptide-4, nisin, trifluoroacetyl tripeptide-2, tripeptide-1, tripeptide-1 copper, tripeptide-10 citrulline, tripeptide-2, tripeptide-3, and tripeptide-32. At least one of the following: decatheptide-1, decatheptide-4, retinol / yeast polypeptide, tetrapeptide-1, tetrapeptide-3, tetrapeptide-4, decarboxylated carnosine hydrochloride, pentapeptide-1, pentapeptide-3, acetyl octapeptide-3, acetyl hexapeptide-1, acetyl hexapeptide-7, acetyl hexapeptide-8, acetyl heptapeptide-4, acetyl tripeptide-1, acetyl tetrapeptide-11, acetyl tetrapeptide-2, acetyl tetrapeptide-3, acetyl tetrapeptide-5, acetyl tetrapeptide-9, palmitoyl dipeptide-7, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12, palmitoyl hexapeptide-12, palmitoyl hexapeptide-14, palmitoyl hexapeptide-15, palmitoyl tripeptide-1, palmitoyl tripeptide-5, palmitoyl tripeptide-8, palmitoyl tetrapeptide-10, palmitoyl tetrapeptide-5, palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, and palmitoyl pentapeptide-5.

[0031] In a preferred embodiment, the system further comprises other liquid oils at room temperature, excluding meadowfoam seed oil, wherein the content of the other liquid oils is at least 29 wt%, preferably 29.3-40.5 wt%.

[0032] In a preferred embodiment, the other liquid oils are selected from: squalane, caprylic / capric triglycerides, C9-12 alkylene, vitamin E acetate, vitamin E, jojoba oil, isononyl isononanoate, cetyl ethylhexanoate, cetearyl ethylhexanoate, cetearyl isononanoate, dioctyl carbonate, diethylhexyl carbonate, triethylhexyl glycerol, dibutyl adipate, pentaerythritol tetra(ethylhexanoate), cocoyl octanoate, cocoyl octanoate, etc. The following are at least one of the following: esters / decanoates, decyl cocoate, oleyl erucic acid ester, ethylhexyl palmitate, ethylhexyl stearate, C12-15 benzoate, isooctyl palmitate, isopropyl palmitate, isopropyl myristate, hexyl laurate, octyl dodecyl alcohol, octyl dodecyl myristate, dioctyl ether, hexyl decyl alcohol, hexyl decyl laurate, octyl caprylic / decanoate, propyl heptyl caprylate, decyl oleate, glyceryl cocoate esters, and hydrogenated polyisobutylene.

[0033] The present invention also provides a transparent, uniformly sized essential oil comprising a transparent essential oil system based on meadowfoam seed oil.

[0034] In a preferred embodiment, the system contains 0.001-100 wt% of the essential oil.

[0035] The beneficial effects of this invention are:

[0036] The present invention unexpectedly discovered that oleyl alcohol polyether-3 phosphate and water-soluble cosmetic raw materials can be solubilized in meadowfoam seed oil in a certain ratio (such as 6:1 to 10:1, preferably 8:1 to 10:1). When the solubilized composition is added to an essential oil containing meadowfoam seed oil, the essential oil can still maintain its transparent appearance and remain unchanged.

[0037] This invention provides a composition containing oleyl alcohol polyether-3-phosphate and water-soluble active ingredients. Taking meadowfoam seed oil as an example, this composition can be used not only in systems where meadowfoam seed oil is the single oil, but also in essential oil systems where meadowfoam seed oil is the main oil and contains other mixed oils, so that the essential oil still maintains a transparent appearance. This solves the technical problem of applying water-soluble active ingredients to essential oils.

[0038] The composition of this invention comprises three components: oleyl alcohol polyether-3-phosphate, water-soluble active ingredients, and meadowfoam seed oil. The water-soluble active ingredients include, but are not limited to, the following: various plant extracts, water-soluble polypeptides, lactobacillus / yeast fermentation broth and fermentation products, as well as other water-soluble vitamins, amino acids, sugars or polysaccharides, etc. Attached Figure Description

[0039] Figure 1 This is a photograph taken after the preparation of Example 5 was completed;

[0040] Figure 2 The image shown is a photograph of Comparative Example 2 after preparation. Detailed Implementation

[0041] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. While any methods and materials similar or equivalent to those described herein may be used to practice or test the invention, preferred methods and materials are described herein. For the purposes of this invention, the following terms are defined.

[0042] To provide a more concise description, some of the quantitative expressions given herein are not modified by the term "approximately". It should be understood that, whether or not the term "approximately" is explicitly used, each quantity given herein is intended to refer to an actual given value, and also to an approximation of such given values ​​that can be reasonably inferred by one of ordinary skill in the art, including approximations of such given values ​​caused by experimental and / or measurement conditions.

[0043] To provide a more concise description, some quantities in this document are described as a range from approximately X to approximately Y. It should be understood that when describing a range, the range is not limited to the upper and lower limits stated, but should include the entire range from approximately X to approximately Y, or any quantities in between.

[0044] A transparent essential oil system based on meadowfoam seed oil

[0045] The transparent essential oil system based on meadowfoam seed oil of the present invention has a meadowfoam seed oil content of ≥50wt% in the composition, preferably 50-99.99wt%, and even more preferably 59.32-99.4wt%.

[0046] Emulsifying solubilizer

[0047] The emulsifying solubilizer of the present invention is an oil-soluble amphiphilic surfactant with an HLB value of 5-12. The emulsifying solubilizer is selected from at least one of oleyl alcohol polyether-3 phosphate, polyglycerol-3 polyricinoleate, and lauryl alcohol polyether-4, preferably oleyl alcohol polyether-3 phosphate.

[0048] Water-soluble functional ingredients

[0049] The water-soluble active ingredients described in this invention include, but are not limited to, the following: various plant extracts, water-soluble polypeptides, fermentation broth and fermentation products, as well as other water-soluble vitamins, amino acids, sugars or polysaccharides, etc.

[0050] The plant extract has a solid content ≥1 wt%, preferably 1-7.5 wt%, and even more preferably 1.4-7.5 wt%.

[0051] The plant extracts are selected from at least one of the following: Lindera strychnifolia, Portulaca oleracea, Lotus, Ginseng, Ganoderma lucidum, Artemisia annua, Polygonatum sibiricum, Astragalus membranaceus, Scutellaria baicalensis, Poria cocos, Paeonia lactiflora, Paeonia suffruticosa, Saussurea involucrata, Tuberculum truncata, Dendrobium nobile, Ginkgo biloba, Lycium barbarum, Perilla frutescens, Ganoderma lucidum, Hippophae rhamnoides, Ligusticum chuanxiong, Angelica sinensis, Polygonum multiflorum, Rehmannia glutinosa, Leonurus japonicus, Salvia miltiorrhiza, Epiphyllum oxypetalum, Osmanthus fragrans, Magnolia officinalis, Cherry blossom, Centella asiatica, Oat, Dioscorea opposita, Polygonatum odoratum, Orchid, Glycyrrhiza uralensis, Aloe vera, Fig, Peppermint, Atractylodes lancea, Artemisia argyi, Cedarwood, Sequoia glyptostroboides, Witch hazel, Lupinus oleracea, Pea, Schisandra chinensis, Sapindus mukorossi, Cuscuta chinensis, Cistanche deserticola, Nutmeg, Sesame, Ophiopogon japonicus, Tea, Carrot, Papaya, Coconut, Grape, Lemon, Cactus, Gynostemma pentaphyllum, Rhodiola rosea, etc., and are water-soluble extracts obtained from the roots / stems / branches / leaves / flowers / seeds / kernels / barks / whole plants.

[0052] The solid content of the fermentation broth and fermentation product is ≥0.9wt%, preferably 0.9-5wt%, and even more preferably 1.5-3.0wt%. The fermentation broth and fermentation product are selected from: Bifida ferment lysate, Bifida ferment filtrate, Bifida ferment extract, rice ferment filtrate, Fermentosoma ferment extract, Galactomyces ferment filtrate, red yeast rice / rice fermentation product, Pseudomonas aeruginosa ferment extract, Alternaria aeruginosa ferment extract, yeast ferment extract, yeast / soybean protein fermentation product, yeast / rice ferment filtrate, yeast fermentation product, and yeast fermentation product. The fermentation product filtrate, yeast fermentation lysate filtrate, yeast / Acetobacter xylinum / black tea fermentation product, Lactobacillus / soybean fermentation product extract, Lactobacillus / soybean extract fermentation product filtrate, Lactobacillus / rice fermentation product, Lactobacillus / soy milk fermentation product filtrate, Lactobacillus fermentation product, Lactobacillus fermentation lysate, Lactobacillus / milk fermentation lysate, Lactobacillus fermentation product, Lactobacillus fermentation lysate, Lactobacillus / milk fermentation lysate, Lactobacillus fermentation product, Lactobacillus fermentation lysate, Lactobacillus fermentation extract, Streptococcus thermophilus fermentation product, Thermostable thermophilus fermentation product, Oscillatoria hygroscopica fermentation product, Bacillus / soybean fermentation product extract, Bacillus / glutamate fermentation product filtrate, Bacillus / rice bran extract / soybean extract fermentation product filtrate, and Bacillus fermentation product.

[0053] The water-soluble polypeptides contain ≥50 ppm of polypeptides, preferably ≥100 ppm, and even more preferably 350 ppm-20000 ppm of polypeptides. The water-soluble polypeptides are selected from anti-wrinkle polypeptides, soybean polypeptides, wheat peptides, oat peptides, wild soybean peptides, glutathione, dipeptide diaminobutyryl benzylamide diacetate, carnosine, yeast polypeptides, and alanine / histidine / lysine. Copper Hydrochloride, Arginine / Lysine Peptide, Dipeptide-1, Dipeptide-2, Dipeptide-4, Dipeptide-15, Oligopeptide-1, Oligopeptide-2, Oligopeptide-29, Oligopeptide-3, Oligopeptide-32, Oligopeptide-4, Oligopeptide-5, Oligopeptide-6, Nonapeptide-1, Hexapeptide-1, Hexapeptide-11, Hexapeptide-2, Hexapeptide-3, Hexapeptide-5, Hexapeptide-9, Heptapeptide-6, Myristoyl Hexapeptide-5, Myristoyl Pentapeptide-4, Nipponil Peptide, Trifluoroacetyl Tripeptide-2 Tripeptide-1, Tripeptide-1 Copper, Tripeptide-10 Citrulline, Tripeptide-2, Tripeptide-3, Tripeptide-32, Tridecapeptide-1, Decapeptide-4, Retinol / Yeast Polypeptide, Tetrapeptide-1, Tetrapeptide-3, Tetrapeptide-4, Decarboxylated Carnosine Hydrochloride, Pentapeptide-1, Pentapeptide-3, Acetyl Octapeptide-3, Acetyl Hexapeptide-1, Acetyl Hexapeptide-7, Acetyl Hexapeptide-8, Acetyl Heptapeptide-4, Acetyl Tripeptide-1, Acetyl Tetrapeptide-11, Acetyl At least one of the following: tetrapeptide-2, acetyl tetrapeptide-3, acetyl tetrapeptide-5, acetyl tetrapeptide-9, palmitoyl dipeptide-7, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12, palmitoyl hexapeptide-12, palmitoyl hexapeptide-14, palmitoyl hexapeptide-15, palmitoyl tripeptide-1, palmitoyl tripeptide-5, palmitoyl tripeptide-8, palmitoyl tetrapeptide-10, palmitoyl tetrapeptide-5, palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, and palmitoyl pentapeptide-5.

[0054] Other liquid oils

[0055] The other liquid oils mentioned in this invention are oil raw materials that are liquid at room temperature, excluding meadowfoam seed oil. These other oils are selected from: squalane, caprylic / capric triglycerides, C9-12 alkylene, vitamin E acetate, vitamin E, jojoba oil, isononyl isononanoate, cetyl ethylhexanoate, cetearyl ethylhexanoate, cetearyl isononanoate, dioctyl carbonate, diethylhexyl carbonate, triethylhexyl glycerol, dibutyl adipic acid, pentaerythritol tetra(ethylhexanoate), and coconut oil alcohol. -At least one of the following: octanoate, cocoyl octanoate / decanoate, decyl cocoate, oleyl erucate, ethylhexyl palmitate, ethylhexyl stearate, C12-15 benzoate, isooctyl palmitate, isopropyl palmitate, isopropyl myristate, hexyl laurate, octyl dodecyl alcohol, octyl dodecyl myristate, dioctyl ether, hexyl decyl alcohol, hexyl decyl laurate, octanoic acid / decanoate, propyl heptaethyl octanoate, decyl oleate, glyceryl cocoate esters, and hydrogenated polyisobutylene.

[0056] The following describes the technical solution of the present invention in detail through preferred embodiments. However, the scope of the present invention is not limited to these embodiments, which are intended to illustrate the technical solution of the present invention and not to limit the scope of the present invention. Test methods in the following embodiments that do not specify specific conditions are generally performed under conventional conditions or as recommended by the manufacturer. Unless otherwise stated, all percentages and parts are by weight.

[0057] The experimental materials used in the embodiments of the present invention are as follows:

[0058] I. Experimental Materials

[0059]

[0060]

[0061] II. Experimental Instruments

[0062] 1. Fixed mixer IKA RW20

[0063] 2. Electric Thermostatic Water Bath, Shanghai Yiheng Scientific Instruments Co., Ltd., Model HWS28

[0064] 3. Weighing balance METTLER TOLEDO PL602-S

[0065] 4. Jiemeng brand ultrasonic cleaner JP-060S model

[0066] 5. 48℃ drying oven: MMM group MMM707

[0067] 6.4℃ Refrigerator: MMM group FRIOCELL 707 90570

[0068] 7. -18℃ Refrigerator: Haier DW-40L

[0069] Test Example 1: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0070] Add 1g of oleyl alcohol polyether-3 phosphate to 10g of meadowfoam seed oil, stir and mix well to obtain a yellow transparent liquid, which remains unchanged after standing for 12 hours.

[0071] Test Example 2: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0072] Add 2g of oleyl alcohol polyether-3 phosphate to 10g of meadowfoam seed oil, stir and mix well to obtain a yellow transparent liquid, which remains unchanged after standing for 12 hours.

[0073] Test Example 3: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0074] Add 4g of oleyl alcohol polyether-3 phosphate to 10g of meadowfoam seed oil, stir and mix well to obtain a yellow transparent liquid, which remains unchanged after standing for 12 hours.

[0075] Test Example 4: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0076] Add 1g of oleyl alcohol polyether-3 to 10g of meadowfoam seed oil, stir and mix well to obtain a light yellow liquid, which immediately contains filamentous insoluble matter suspended in the liquid.

[0077] Test Example 5: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0078] Add 2g of oleyl alcohol polyether-3 to 10g of meadowfoam seed oil, stir and mix well to obtain a light yellow liquid, which immediately contains filamentous insoluble matter suspended in the liquid.

[0079] Test Example 6: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0080] Add 4g of oleyl alcohol polyether-3 to 10g of meadowfoam seed oil, stir and mix well to obtain a light yellow liquid, which immediately contains filamentous insoluble matter suspended in the liquid.

[0081] Test Example 7: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0082] Add 1g of oleyl alcohol polyether-5 to 10g of meadowfoam seed oil and stir until well mixed to obtain a yellow turbid liquid.

[0083] Test Example 8: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0084] Add 2g of oleyl alcohol polyether-5 to 10g of meadowfoam seed oil and stir until well mixed to obtain a yellow turbid liquid.

[0085] Test Example 9: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0086] Add 4g of oleyl alcohol polyether-5 to 10g of meadowfoam seed oil and stir until well mixed to obtain a yellow turbid liquid.

[0087] Test Example 10: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0088] Add 1g of polyglycerol-3 diisostearate to 10g of meadowfoam seed oil, stir and mix well to obtain a light yellow misty liquid.

[0089] Test Example 11: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0090] Add 2g of polyglycerol-3 diisostearate to 10g of meadowfoam seed oil, stir and mix well to obtain a light yellow misty liquid.

[0091] Test Example 12: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0092] Add 4g of polyglycerol-3 diisostearate to 10g of meadowfoam seed oil, stir and mix well to obtain a light yellow misty liquid.

[0093] Test Example 13: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0094] Add 1g of polyglycerol-3 polyricinoleate to 10g of meadowfoam seed oil, stir and mix well to obtain a yellow transparent liquid, which remains unchanged after standing for 12 hours.

[0095] Test Example 14: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0096] Add 2g of polyglycerol-3 polyricinoleate to 10g of meadowfoam seed oil, stir and mix well to obtain a yellow transparent liquid, which remains unchanged after standing for 12 hours.

[0097] Test Example 15: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0098] Add 4g of polyglycerol-3 polyricinoleate to 10g of meadowfoam seed oil, stir and mix well to obtain a yellow transparent liquid, which remains unchanged after standing for 12 hours.

[0099] Test Example 16: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0100] Add 1g of lauryl alcohol polyether-4 to 10g of meadowfoam seed oil, stir and mix well to obtain a light yellow transparent liquid, which remains unchanged after standing for 12 hours.

[0101] Test Example 17: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0102] Add 2g of lauryl alcohol polyether-4 to 10g of meadowfoam seed oil, stir and mix well to obtain a light yellow transparent liquid, which remains unchanged after standing for 12 hours.

[0103] Test Example 18: Screening for emulsifying solubilizers compatible with meadowfoam seed oil

[0104] Add 4g of lauryl alcohol polyether-4 to 10g of meadowfoam seed oil, stir and mix well to obtain a light yellow transparent liquid, which remains unchanged after standing for 12 hours.

[0105] Table 1. Compatibility test between different emulsifying solubilizers and meadowfoam seed oil

[0106]

[0107] Analysis of Table 1 reveals that the emulsifying solubilizers used in Test Examples 4-12, such as oleyl alcohol polyether-3, oleyl alcohol polyether-5, and polyglycerol-3 diisostearate, are immiscible with meadowfoam seed oil. Conversely, the emulsifying solubilizers used in Test Examples 1-3 and 13-18, such as oleyl alcohol polyether-3 phosphate, polyglycerol-3 polyricinoleate, and lauryl alcohol polyether-4, are miscible with meadowfoam seed oil at different ratios. This indicates that oleyl alcohol polyether-3 phosphate, polyglycerol-3 polyricinoleate, lauryl alcohol polyether-4, and meadowfoam seed oil have good compatibility and can be tried as solubilizers in meadowfoam seed oil systems.

[0108] Example 1: Solubilizing Active Ingredients – Taking “Lindera Root Extract” as an Example

[0109] Weigh 0.1g of Lindera root extract and 0.3g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.6g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow turbid liquid.

[0110] Example 2: Solubilizing Active Ingredients – Taking “Lindera Root Extract” as an Example

[0111] Weigh 0.1g of Lindera root extract and 0.5g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.4g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow turbid liquid.

[0112] Example 3: Solubilizing Active Ingredients – Taking “Lindera Root Extract” as an Example

[0113] Weigh 0.1g of Lindera root extract and 0.6g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.3g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow turbid liquid.

[0114] Example 4: Solubilizing Active Ingredients – Taking “Lindera Root Extract” as an Example

[0115] Weigh 0.1g of Lindera root extract and 0.7g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.2g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow semi-transparent mist liquid.

[0116] Example 5: Solubilizing Active Ingredients – Taking “Lindera Root Extract” as an Example

[0117] Weigh 0.1g of Lindera root extract and 0.8g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.1g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow transparent liquid.

[0118] Example 6: Solubilizing Active Ingredients – Taking “Lindera Root Extract” as an Example

[0119] Weigh 0.1g of Lindera root extract and 0.9g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.0g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow transparent liquid.

[0120] Counterexample 1: Solubilizing active ingredients – taking “Lindera root extract” as an example

[0121] 0.1g of Lindera root extract, 0.8g of oleyl alcohol polyether-3 phosphate, and 99.1g of meadowfoam seed oil were weighed and dissolved by stirring or sonication at room temperature to 40℃ to obtain a turbid liquid.

[0122] Comparative Example 1: Solubilizing Active Ingredients – Taking “Lindera Root Extract” as an Example

[0123] Weigh 0.1g of Lindera root extract and 0.8g of polyglycerol-3 polyricinoleate, stir and mix evenly to form a gel, then add 99.1g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow turbid liquid.

[0124] Comparative Example 2: Solubilizing Active Ingredients – Taking “Lindera Root Extract” as an Example

[0125] Weigh 0.1g of Lindera root extract and 0.8g of lauryl alcohol polyether-4, stir and mix evenly to form a gel, then add 99.1g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow turbid liquid.

[0126] Analysis of Examples 1-6 revealed that in the meadowfoam seed oil system, the solubilization of Lindera root extract could only be achieved when the ratio of oleyl alcohol polyether-3 phosphate to Lindera root extract was ≥8 / 1. When the ratio of oleyl alcohol polyether-3 phosphate to Lindera root extract was <8 / 1 (i.e., 3 / 1 to 7 / 1), the solubilization of Lindera root extract could not be achieved.

[0127] This indicates that solubilizing Lindera root extract in meadowfoam seed oil is relatively difficult, requiring the addition of a high concentration of solubilizer, specifically oleyl alcohol polyether-3-phosphate / Lindera root extract ≥ 8 / 1. This may be related to the inherent properties of plant oils, as their main components include unsaturated fatty acids, saturated fatty acids, polyunsaturated fatty acids, vitamins, and organic acids, making their composition quite complex. Based on the solubilization results of oleyl alcohol polyether-3-phosphate in meadowfoam seed oil, it is possible to achieve solubilization of Lindera root extract in plant oil systems such as meadowfoam seed oil. However, a relatively high concentration of oleyl alcohol polyether-3-phosphate is required, such as achieving the ≥ 8 / 1 ratio shown in Examples 5 and 6.

[0128] Analysis of Example 5 and Comparative Examples 1-2 revealed that although polyglycerol-3 polyricinoleate and lauryl ether-4 have good compatibility with meadowfoam seed oil, their use as solubilizers to solubilize Lindera root extract in meadowfoam seed oil was not ideal. Even when the emulsification solubilizer / Lindera root extract ratio reached 8:1, polyglycerol-3 polyricinoleate and lauryl ether-4 still failed to solubilize Lindera root extract. This indicates that in the meadowfoam seed oil system, oleyl alcohol polyether-3 phosphate can solubilize Lindera root extract at a ratio ≥8:1, while polyglycerol-3 polyricinoleate and lauryl ether-4 cannot achieve solubilization. This further demonstrates that the solubilizing ability of a solubilizer is unrelated to the compatibility between the solubilizer itself and the oil.

[0129] Furthermore, a comparison between Example 5 and Counterexample 1 shows that while the components and contents of the two groups are completely identical, the difference lies in the solubilization technique described in this invention. Specifically, the emulsifying solubilizer and the water-soluble active ingredient are pre-mixed to form a solubilizing gel, which is then mixed with meadowfoam seed oil to obtain a transparent and homogeneous liquid. In contrast, Counterexample 1 directly mixes the emulsifying solubilizer, the water-soluble active ingredient, and the meadowfoam seed oil, resulting in a turbid liquid, indicating that the solubilization of the water-soluble active ingredient in the meadowfoam seed oil system was not successfully achieved. This further illustrates that even with identical component types and contents, the success of solubilization is closely related to the order of addition and mixing method of the components.

[0130] Example 7: Solubilizing other plant extracts

[0131] Weigh 0.1g of purslane extract and 0.8g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.1g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow transparent liquid.

[0132] Example 8: Solubilizing other plant extracts

[0133] Weigh 0.1g of purslane extract and 0.7g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.2g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow transparent liquid.

[0134] Example 9: Solubilizing other plant extracts

[0135] Weigh 0.1g of purslane extract and 0.6g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.3g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow transparent liquid.

[0136] Example 10: Solubilizing other plant extracts Weigh 0.1g of purslane extract and 0.5g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.4g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40°C to obtain a yellow turbid liquid.

[0137] Counterexample 2: Solubilizing other plant extracts

[0138] Weigh out 0.1g of purslane extract, 0.8g of oleyl alcohol polyether-3 phosphate, and 99.1g of meadowfoam seed oil, and dissolve them by stirring or sonication at room temperature to 40°C to obtain a turbid liquid.

[0139] Analysis of Examples 7 to 10 revealed that in the meadowfoam seed oil system, the oleyl alcohol polyether-3 phosphate / purslane extract ratio ≥ 6 / 1 can achieve solubilization of purslane extract, while the ratio < 6 / 1 (e.g., 5 / 1) cannot achieve solubilization.

[0140] Comparative analysis of Examples 7 to 10 and Examples 1 to 6 revealed that, within the same meadowfoam seed oil system, the solubilizing effect of oleyl alcohol polyether-3-phosphate varies depending on the water-soluble extract. Specifically, when solubilizing Lindera root extract, the ratio of oleyl alcohol polyether-3-phosphate to Lindera root extract needs to be ≥8 / 1, while when solubilizing Portulaca oleracea extract, only a ratio of oleyl alcohol polyether-3-phosphate to Portulaca oleracea extract needs to be ≥6 / 1. This indicates that the solubilizing effect of oleyl alcohol polyether-3-phosphate in the meadowfoam seed oil system is closely related to the properties of the water-soluble extract, and different plant extracts will exhibit different solubilizing effects.

[0141] Example 11: Solubilizing other plant extracts

[0142] Weigh 0.1g of lotus extract and 0.6g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.3g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow misty liquid.

[0143] Example 12: Solubilizing other plant extracts

[0144] Weigh 0.1g of lotus extract and 0.7g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.2g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow transparent liquid.

[0145] Example 13: Solubilizing other plant extracts

[0146] Weigh 0.1g of lotus extract and 0.8g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.1g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow transparent liquid.

[0147] Counterexample 3: Solubilizing other plant extracts

[0148] Weigh out 0.5g of lotus extract, 0.7g of oleyl alcohol polyether-3 phosphate, and 99.2g of meadowfoam seed oil, and dissolve them by stirring or sonication at room temperature to 40°C to obtain a turbid liquid.

[0149] Analysis of Examples 11 to 13 revealed that in the meadowfoam seed oil system, a ratio of oleyl alcohol polyether-3-phosphate to lotus extract ≥ 7 / 1 could solubilize lotus extract, while a ratio of oleyl alcohol polyether-3-phosphate to purslane extract < 7 / 1 (e.g., 6 / 1) could not solubilize it. This indicates that the solubilizing effect of different plant extracts varies in the meadowfoam seed oil system, specifically: a ratio of oleyl alcohol polyether-3-phosphate to Lindera root extract ≥ 8 / 1 can solubilize Lindera root extract; a ratio of oleyl alcohol polyether-3-phosphate to purslane extract ≥ 6 / 1 can solubilize purslane extract; and a ratio of oleyl alcohol polyether-3-phosphate to lotus extract ≥ 7 / 1 can solubilize lotus extract.

[0150] The above results further demonstrate that when oleyl alcohol polyether-3 phosphate is used to solubilize water-soluble extracts in meadowfoam seed oil system, its solubilizing effect is closely related to the properties of the water-soluble extracts, and different solubilizing effects will be observed for different plant extracts.

[0151] Furthermore, comparing Example 7 with Counterexample 2, and Example 12 with Counterexample 3, it can be seen that the components and contents of the two groups are completely identical. However, the difference lies in the fact that Example 7 and Example 12 employed the solubilization technology described in this invention, that is, the emulsifying solubilizer and the water-soluble active ingredient were pre-mixed to form a solubilizing phase gel, and then the solubilizing phase gel was mixed with meadowfoam seed oil to obtain a transparent and uniform liquid. In contrast, Counterexample 2 and Counterexample 3 directly mixed the emulsifying solubilizer, the water-soluble active ingredient, and the meadowfoam seed oil, resulting in a turbid liquid, indicating that the solubilization of the water-soluble active ingredient in the meadowfoam seed oil system was not successfully achieved. This further illustrates that even if the types and contents of components are completely identical, the success of solubilization is closely related to the order of addition and the mixing method of the components.

[0152] Example 14: Active ingredients in solubilized yeast fermentation broth

[0153] Weigh 0.1g of Bifida ferment lysate and 0.6g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.3g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a light yellow semi-transparent mist liquid.

[0154] Example 15: Active ingredients in solubilized yeast fermentation broth

[0155] Weigh 0.1g of Bifida ferment lysate and 0.7g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.2g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a light yellow semi-transparent mist liquid.

[0156] Example 16: Active ingredients in solubilized yeast fermentation broth

[0157] Weigh 0.1g of Bifida ferment lysate and 0.8g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.1g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a light yellow transparent liquid.

[0158] Counterexample 4: Solubilizing yeast fermentation liquid as a type of functional ingredient

[0159] Weigh out 0.1g of Bifida ferment lysate, 0.8g of oleyl alcohol polyether-3 phosphate, and 99.1g of meadowfoam seed oil, and dissolve them by stirring or sonication at room temperature to 40°C to obtain a turbid liquid.

[0160] Analysis of Examples 14 to 16 revealed that, in the meadowfoam seed oil system, the solubilization of Bifida ferment lysate can only be achieved when the ratio of oleyl alcohol polyether-3 phosphate to Bifida ferment lysate is ≥8 / 1.

[0161] Furthermore, a comparison between Example 16 and Counterexample 4 reveals that while the components and contents of the two groups are completely identical, the difference lies in the solubilization technique described in this invention. Specifically, the emulsifying solubilizer and the water-soluble active ingredient are pre-mixed to form a solubilizing gel, which is then mixed with meadowfoam seed oil to obtain a transparent and homogeneous liquid. In contrast, Counterexample 4 directly mixes the emulsifying solubilizer, the water-soluble active ingredient, and the meadowfoam seed oil, resulting in a turbid liquid, indicating that the solubilization of the water-soluble active ingredient in the meadowfoam seed oil system was not successfully achieved. This further illustrates that even with identical component types and contents, the success of solubilization is closely related to the order of addition and mixing method of the components.

[0162] Example 17: Solubilizing polypeptide active ingredients

[0163] Weigh 0.1g of anti-wrinkle peptide and 0.6g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a light yellow gel, then add 99.3g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow transparent liquid.

[0164] Example 18: Solubilizing polypeptide active ingredients

[0165] Weigh 0.1g of anti-wrinkle peptide and 0.5g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.4g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a yellow transparent liquid.

[0166] Example 19: Solubilizing polypeptide active ingredients

[0167] Weigh 0.1g of anti-wrinkle peptide and 0.4g of oleyl alcohol polyether-3 phosphate, stir and mix evenly to form a milky yellow gel, then add 99.5g of meadowfoam seed oil, and dissolve by stirring or sonication at room temperature to 40℃ to obtain a light yellow semi-transparent mist liquid.

[0168] Counterexample 5: Solubilizing polypeptide functional ingredients

[0169] Weigh out 0.1g of anti-wrinkle peptide, 0.5g of oleyl alcohol polyether-3 phosphate and 99.4g of meadowfoam seed oil respectively, and dissolve them by stirring or sonication at room temperature to 40℃ to obtain a turbid liquid.

[0170] Analysis of Examples 17-19 revealed that in the meadowfoam seed oil system, the solubilization of anti-wrinkle peptides only requires that the ratio of oleyl alcohol polyether-3 phosphate to anti-wrinkle peptides be ≥5 / 1. Compared with the solubilization of plant extract raw materials and Bifida ferment lysate, oleyl alcohol polyether-3 phosphate is relatively easier to achieve in the meadowfoam seed oil system for solubilizing anti-wrinkle peptides.

[0171] Furthermore, a comparison between Example 18 and Counterexample 5 reveals that while the components and contents of the two groups are completely identical, the difference lies in the solubilization technique described in this invention. Specifically, the emulsifying solubilizer and the water-soluble active ingredient are pre-mixed to form a solubilizing gel, which is then mixed with meadowfoam seed oil to obtain a transparent and homogeneous liquid. In contrast, Counterexample 5 directly mixes the emulsifying solubilizer, the water-soluble active ingredient, and the meadowfoam seed oil, resulting in a turbid liquid, indicating that the solubilization of the water-soluble active ingredient in the meadowfoam seed oil system was not successfully achieved. This further illustrates that even with identical component types and contents, the success of solubilization is closely related to the order of addition and mixing method of the components.

[0172] Preparation of essential oils with meadowfoam seed oil as the main oil

[0173] Application Example 1: Preparation of an essential oil containing Lindera root extract

[0174]

[0175] Application Example 2: Preparation of essential oils containing Bifida ferment lysate.

[0176]

[0177] Application Example 3: Preparation of an essential oil containing anti-wrinkle peptides

[0178]

[0179]

Claims

1. The use of oleyl alcohol polyether-3-phosphate in solubilizing water-soluble raw materials in a meadowfoam seed oil transparent essential oil system, wherein the meadowfoam seed oil transparent essential oil system is composed of meadowfoam seed oil, oleyl alcohol polyether-3-phosphate, and water-soluble active ingredients, wherein... Based on the total weight of the system The content of meadowfoam seed oil is 59.32-99.4 wt%. The content of the oleyl alcohol polyether-3 phosphate ester is 0.8-7.5 wt%. The water-soluble active ingredient is Lindera root extract, and the weight ratio of the oleyl alcohol polyether-3 phosphate ester to the Lindera root extract is 8:1 to 9:

1. Alternatively, the water-soluble active ingredient may be purslane extract, and the weight ratio of the oleyl alcohol polyether-3 phosphate ester to the purslane extract may be 6:1 to 8:

1. Alternatively, the water-soluble active ingredient may be lotus extract, and the weight ratio of the oleyl alcohol polyether-3 phosphate to the lotus extract may be 7:1 to 8:

1. Alternatively, the water-soluble active ingredient may be Bifida ferment lysate, and the weight ratio of the oleyl alcohol polyether-3 phosphate to the Bifida ferment lysate may be 8:

1. The transparent essential oil system is obtained by pre-mixing oleyl alcohol polyether-3 phosphate with water-soluble active ingredients to form a solubilizing phase gel, and then mixing the solubilizing phase gel with meadowfoam seed oil to obtain a transparent and uniform liquid.

Citation Information

Patent Citations

  • A silicone-free shampoo conditioning agent composition, a silicone-free shampoo and its preparation method

    CN109044857B

  • Preparation method of micro-emulsified essence

    CN110934795A