A traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method and application thereof

Abstract

The application provides a traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 20-30 parts of rhizoma angelicae pubescentis, 3-7 parts of safflower, 8-12 parts of vinegar-labdanum, 5-10 parts of chuanxiong rhizome, 15-25 parts of ramulus cinnamomi, 20-30 parts of radix astragali, 20-30 parts of schizonepeta, 5-10 parts of zanthoxylum, 10-15 parts of vinegar-myrrh, 20-30 parts of radix alstroemeriae, 20-30 parts of chaenomelis, 12-18 parts of radix saposhnikoviae, 20-30 parts of radix glehniae, 15-25 parts of radix clematidis, and 20-30 parts of radix rubi. The traditional Chinese medicine composition has a good curative effect on rheumatoid arthritis.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method and application thereof. BACKGROUND

[0002] Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation, swelling, and dysfunction. RA gradually damages the cartilage and bone of the joints, leading to joint deformity and severely affecting the quality of life of patients. In addition, RA can also cause involvement of internal organs such as the heart and lungs, and in severe cases can cause complications such as pericarditis and pulmonary fibrosis.

[0003] Some RA drugs may have serious side effects, while traditional Chinese medicine often has less risk of side effects. Therefore, researching traditional Chinese medicine formulations can provide safer treatment options for RA patients. SUMMARY

[0004] In view of this, the present application provides a traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method and application thereof.

[0005] The technical solution of the present application is as follows:

[0006] A traditional Chinese medicine composition for treating rheumatoid arthritis, comprising the following weight parts of traditional Chinese medicinal materials: 20-30 parts of Angelica pubescens, 3-7 parts of Carthamus tinctorius, 8-12 parts of Commiphora myrrha, 5-10 parts of Ligusticum chuanxiong, 15-25 parts of Ramulus cinnamomi, 20-30 parts of Radix Millettiae, 20-30 parts of Schizonepeta tenuifolia, 5-10 parts of Zanthoxylum bungeanum, 10-15 parts of Commiphora myrrha, 20-30 parts of Alpinia chinensis, 20-30 parts of Chaenomeles speciosa, 12-18 parts of Saposhnikovia divaricata, 20-30 parts of Notopterygium incisum, 15-25 parts of Cynanchum koushienense, 20-30 parts of Dipsacus asper, and 23-27 parts of Radix et Rhizoma Polygoni Cuspidati.

[0007] Further, the traditional Chinese medicine composition for treating rheumatoid arthritis comprises the following weight parts of traditional Chinese medicinal materials: 23-27 parts of Angelica pubescens, 4-6 parts of Carthamus tinctorius, 9-11 parts of Commiphora myrrha, 7-9 parts of Ligusticum chuanxiong, 18-22 parts of Ramulus cinnamomi, 23-27 parts of Radix Millettiae, 23-27 parts of Schizonepeta tenuifolia, 7-9 parts of Zanthoxylum bungeanum, 12-14 parts of Commiphora myrrha, 23-27 parts of Alpinia chinensis, 23-27 parts of Chaenomeles speciosa, 14-16 parts of Saposhnikovia divaricata, 23-27 parts of Notopterygium incisum, 18-22 parts of Cynanchum koushienense, and 23-27 parts of Dipsacus asper.

[0008] Further, the traditional Chinese medicine composition for treating rheumatoid arthritis comprises the following ingredients by weight: 25 parts of angelica pubescens, 5 parts of safflower, 10 parts of vinegar frankincense, 8 parts of chuanxiong, 20 parts of cassia twig, 25 parts of radix astragali, 8 parts of zanthoxylum, 13 parts of vinegar myrrh, 25 parts of impatiens balfourii, 25 parts of papaya, 15 parts of siler, 25 parts of notopterygium, 20 parts of radix dipsaci, 25 parts of radix dipsaci.

[0009] Further, the frankincense is vinegar frankincense.

[0010] Further, the myrrh is vinegar myrrh.

[0011] The traditional Chinese medicine composition for treating rheumatoid arthritis in any of the present application is applied in the preparation of a medicine for treating rheumatoid arthritis.

[0012] Compared with the prior art, the present application has the following beneficial effects:

[0013] (1) The traditional Chinese medicine formula for rheumatoid arthritis can simultaneously regulate the immune system, reduce inflammation, improve blood circulation and other aspects, and has better comprehensive treatment effect, and has significant effect on treating rheumatoid arthritis.

[0014] (2) The traditional Chinese medicine formula in the present application is scientifically matched based on the principle of monarch, minister, assistant and guide. Among them, angelica pubescens is pungent and warm, and belongs to kidney and bladder meridians, and can dispel wind and dampness, relieve pain and relieve pain.

[0015] Notopterygium is pungent, bitter and warm, and belongs to bladder and kidney meridians, and can relieve the surface cold, dispel wind and dampness, and relieve pain. Notopterygium is especially good at rising qi, which can directly rise to the top of the head and horizontally move the limbs and arms to perform the function of dispelling wind and relieving pain. Angelica pubescens can only pass through the chest, abdomen, waist, knees and ears. The teacher of the door always uses notopterygium to mainly treat upper wind, cold and dampness, which is completely different from the use of angelica pubescens to mainly treat the lower part of the body. Kidney is the main bone, rheumatoid arthritis is mainly bone joint disease, and rheumatoid arthritis is mainly caused by wind, cold, dampness and heat evil blocking in the collaterals, which can relieve pain and relieve pain. The two are monarch drugs.

[0016] Safflower can activate blood and relieve pain, dispel blood stasis and relieve pain. Modern research shows that safflower extract safflower yellow pigment has analgesic and sedative effect on experimental mice. Chuanxiong is pungent and warm, and belongs to liver, gallbladder and pericardium meridians, and can move qi, dispel wind and dampness, and activate blood to relieve pain. Mastic is pungent, bitter and warm, and can activate blood, promote blood circulation, relieve pain and promote tissue regeneration, and is used for treating various rheumatic arthralgia, muscle and tendon contracture, contusion, injury, abscess and ulcer. Myrrh is pungent, bitter and flat, and can dispel blood stasis, relieve pain, promote tissue regeneration, and is often used together with mastic. Mastic and myrrh are important drugs for promoting the circulation of viscera and meridians, so they can be used to treat pain in the heart, stomach, hypochondriac region, abdomen, limbs and joints. The four drugs are used together to activate blood and dispel blood stasis, dredge collaterals and relieve pain, and help the monarch drug to relieve pain and relieve pain.

[0017] Ramulus cinnamomi is acrid, sweet and warm, and it is meridian-entering heart, lung and bladder channels. The prescription uses its function of warming meridians to assist the ministerial herbs to dredge the meridians, relieve swelling and relieve pain. Zanthoxylum bungeanum is acrid and warm, and it is meridian-entering spleen, stomach and kidney channels, and it is used to warm middle-jiao and relieve pain.

[0018] It is combined with Radix Saposhnikoviae, Radix Clematidis, Chaenomelis Fructus and Rhizoma Polygoni Cuspidati. Chaenomelis Fructus is sour and warm, and it is meridian-entering liver and spleen channels, and it is used to relax the sinews and activate the collaterals and harmonize the stomach and eliminate dampness. Blood is heated and forced, and the sinews are painful, and qi is damp and stagnated, and the sinews are relaxed and soft. Chaenomelis Fructus cools blood and removes heat, and therefore it can be used to treat the combination of the above syndromes. Radix Saposhnikoviae is acrid and sweet, and it is slightly warm, and it is meridian-entering bladder, liver and spleen channels. It is used to dispel wind and relieve superficies, overcome dampness and relieve pain, relieve convulsion and relieve itching. Radix Clematidis is acrid, salty and warm, and it is meridian-entering bladder channel, and it is used to dispel wind and dampness and dredge the meridians. Rhizoma Polygoni Cuspidati is bitter and acrid and warm, and it is meridian-entering liver, spleen and kidney channels, and it is used to dispel wind and dampness and relax the sinews and activate the collaterals. The combination of the above herbs is used to relax the sinews and activate blood, and dispel wind, cold and dampness from the whole body. The addition of Radix Nelumbinis helps the herbs to descend to the joints. Radix Nelumbinis is sweet, bitter and flat, and it is meridian-entering liver and kidney channels. It is used to disperse blood stasis and resolve abscesses when raw, and it helps the herbs to descend to the joints. Herba Schizonepetae is acrid and warm and light in quality, and it helps the herbs to penetrate the skin and relieve the exogenous pathogen. It is meridian-entering lung and liver channels, and it is used to release the exterior, dispel wind and regulate blood. After being carbon-fried, it also has the function of stopping bleeding. Radix Stephaniae Tetrandrae is acrid, bitter and flat, and it is meridian-entering liver and kidney channels, and it is used to dispel wind and dampness, activate blood and resolve toxin. Through dispelling and removing dampness, it is used to treat the exogenous pathogen of wind, cold and dampness in the body. The combination of the above herbs has the functions of dispelling wind, dispelling cold, dispelling dampness, warming the channels, resolving stasis, relaxing the sinews, removing and descending, and it is used to treat the syndrome of arthralgia caused by wind, cold and dampness, and it has good curative effect. DETAILED DESCRIPTION

[0019] In order to better understand the technical content of the present application, the following specific examples are provided to further illustrate the present application.

[0020] The experimental methods used in the embodiments of the present application are conventional methods unless otherwise specified.

[0021] The materials and reagents used in the embodiments of the present application can be obtained from commercial channels unless otherwise specified.

[0022] Example 1 - Chinese medicine formula for treating rheumatoid arthritis

[0023] Radix Angelicae Pubescentis 25g, Flos Carthami 5g, Olibanum Acetate 10g, Rhizoma Chuanxiong 8g, Ramulus Cinnamomi 20g, Radix Nelumbinis 25g, Herba Schizonepetae 25g, Zanthoxylum bungeanum 8g, Myrrh Acetate 13g, Radix Stephaniae Tetrandrae 25g, Chaenomelis Fructus 25g, Radix Saposhnikoviae 15g, Radix Notopterygii 25g, Radix Clematidis 20g, Rhizoma Polygoni Cuspidati 25g.

[0024] Preparation of Chinese medicine powder: according to the weight ratio, the above-mentioned Chinese medicinal materials are taken and mixed and ground into powder, and the Chinese medicine powder for treating rheumatoid arthritis is obtained.

[0025] Usage of Chinese medicine powder: Take an appropriate amount of Chinese medicine powder, hot water into paste (pains in the affected area of 10 cm * 10 cm, about 20 grams of powder is needed, hot water and drug powder dosage is about 1:1), coated with an open sterile gauze block, external application to the pain site (according to the affected area to choose the appropriate size), then wrapped with plastic wrap, each time for 2 hours, once a day.

[0026] Example 2 - Chinese medicine formula for treating rheumatoid arthritis

[0027] Rhizoma Angelicae Pubescentis 20g, Carthamus tinctorius L. 3g, Olibanum Acetate 8g, Ligusticum Chuanxiong Hort. 5g, Ramulus Cinnamomi 15g, Radix Nelumbinis 20g, Schizonepeta 20g, Zanthoxylum 5g, Myrrha Acetate 10g, Alpinia 20g, Chaenomelis Fructus 30g, Radix Saposhnikoviae 18g, Notopterygium 20g, Radix Clematidis 15g, Rhizoma Polygoni Multiflori 30g.

[0028] Preparation of Chinese medicine powder: Take the above-mentioned Chinese medicinal materials according to the weight ratio, mix and grind into powder, and you get the Chinese medicine powder for treating rheumatoid arthritis.

[0029] Example 3 - Chinese medicine formula for treating rheumatoid arthritis

[0030] Rhizoma Angelicae Pubescentis 30g, Carthamus tinctorius L. 6g, Olibanum Acetate 12g, Ligusticum Chuanxiong Hort. 10g, Ramulus Cinnamomi 25g, Radix Nelumbinis 30g, Schizonepeta 30g, Zanthoxylum 10g, Myrrha Acetate 15g, Alpinia 30g, Chaenomelis Fructus 20g, Radix Saposhnikoviae 12g, Notopterygium 30g, Radix Clematidis 25g, Rhizoma Polygoni Multiflori 20g.

[0031] Preparation of Chinese medicine powder: Take the above-mentioned Chinese medicinal materials according to the weight ratio, mix and grind into powder, and you get the Chinese medicine powder for treating rheumatoid arthritis.

[0032] I. Clinical research

[0033] 1 General information

[0034] This study developed diagnostic criteria and efficacy evaluation criteria according to the "Diagnosis and Treatment Criteria for TCM Syndromes" of the State Administration of Traditional Chinese Medicine. The cases came from patients treated in the hospital, and were randomly divided into study group and control group, with 40 cases in each group.

[0035] 2 Diagnostic criteria

[0036] It meets the RA-related diagnostic criteria in the "2018 China Rheumatoid Arthritis Diagnosis and Treatment Guidelines", and imaging examination shows signs such as narrowing of joint space and destruction of articular surface bone. Patients have typical clinical symptoms such as joint movement limitation and swelling. The diagnosis meets the diagnostic criteria of arthralgia and arthralgia in the "Diagnosis and Treatment Criteria for TCM Syndromes".

[0037] (1) Synovial inflammation for more than 6 weeks;

[0038] (2) Joint swelling more than 3, persistent swelling for more than 6 weeks;

[0039] (3) Wrist, metacarpophalangeal or proximal interphalangeal joint swelling, persistent for more than 6 weeks;

[0040] (4) Symmetrical joint;

[0041] (5) Hand X-ray film changes;

[0042] (6) Subcutaneous nodules;

[0043] (7) Rheumatoid factor positive titer > 1:32.

[0044] With four or more can be diagnosed as RA.

[0045] 3 Inclusion and exclusion criteria

[0046] 3.1 Inclusion criteria:

[0047] ① Western medicine comprehensive diagnosis of rheumatoid arthritis;

[0048] ② Age 18-60 years, regardless of men and women;

[0049] ③ No related treatment of the disease in the past four weeks.

[0050] 3.2 Exclusion criteria:

[0051] ① Women in the preconception, pregnancy or lactation period;

[0052] ② Joint severe deformity or loss of mobility, completely unable to self-care;

[0053] ③ There are heart, liver, kidney and other important organ dysfunction;

[0054] ④ Mental abnormalities;

[0055] ⑤ Institute of drug allergy.

[0056] 4 Treatment method

[0057] Control group: given routine treatment, oral methotrexate tablets 10mg, 1 times a week. Continuous use for 4 weeks.

[0058] Research group: adopt the invention example 1 traditional Chinese medicine composition external application: 25g, safflower 5g, vinegar 10g, chuanqiong 8g, 20g, 25g, 25g, 8g, vinegar 13g, 25g, 25g, 25g, 15g, 25g, 20g, 25g. The above-mentioned drugs are finely ground, take the appropriate amount of powder, hot water into paste (painful parts every 10cm*10cm, about 20 grams of powder is needed, hot water and drug powder dosage is about 1:1), coated with an open sterile gauze block, external application to the painful part (according to the choice of appropriate size), then wrapped with plastic wrap, each external application 2 hours, once a day. 7 times for a course of treatment, 4 courses of treatment.

[0059] 5 Observation index

[0060] (1) Main symptoms: including joint pain, swelling, limited activity, all take 0-3 points, no pain / swelling / limited activity is 0, mild is 1, moderate is 2, severe is 3.

[0061] (2) hypersensitive C reactive protein (CRP): detection of CRP before and after treatment.

[0062] (3) safety: blood, urine routine, liver, kidney function, routine electrocardiogram and other tests, to observe whether there are dizziness, vomiting, diarrhea, rash and other adverse reactions during medication.

[0063] 6 Efficacy criteria

[0064] Clinical control: clinical symptoms, joint function significantly relieved or disappeared, the total score of TCM syndrome after treatment was reduced by ≥95% compared with before treatment.

[0065] Markedly effective: clinical symptoms, joint function improved significantly, 70%≤total score of TCM syndrome reduced<95%.

[0066] Effective: clinical symptoms, joint function improved, 30%≤total score of TCM syndrome reduced<70%.

[0067] No effect: the disease is getting worse or no change.

[0068] Total effective cases = cured cases + markedly effective cases + effective cases

[0069] Total effective rate = total effective cases / total cases x 100%.

[0070] 7 Treatment results

[0071] Table 1 Improvement of clinical symptoms and joint function

[0072] Group Number of cases Clinical control cases Cases of marked effectiveness Effective cases Ineffective cases Total effective cases Total effective rate Control group 40 4 7 6 18 17 42.5％ Study group 40 17 11 10 2 38 95.0％

[0073] Table 2 CRP value reduction after treatment

[0074] Group Number of cases Average CRP value before treatment Average CRP value after treatment Percentage of CRP value reduction Control group 40 34.3 18.7 45.5％ Study group 40 35.2 5.1 85.5％

[0075] The results show that there is a significant difference (p<0.05) between the research group and the comparison group, the clinical symptoms, joint function improvement, and CRP value are obviously decreased, and the prepared medicine in the embodiment of the application can better treat rheumatoid arthritis.

[0076] II. Clinical application - typical cases

[0077] Case 1: Huang, female, 65 years old, complained of “repeated multiple joint pain for more than 30 years, aggravated for 1 week”. The patient complained of no obvious cause for more than 30 years of repeated multiple joint pain, and the initial interphalangeal joint pain was the main symptom. The pain was more obvious when it was cold or the weather changed, and the pain was tolerable. Later, the symptoms gradually worsened, and wrist, knee, and ankle pain occurred. The pain was more severe when it was cold or the weather changed, and it was relieved after 1 hour of activity. The pain was reduced when it was warm. At present, the bilateral interphalangeal joints, wrist joints, and knee joints are painful, and there is occasional joint swelling. The left middle finger, index finger, and ring finger interphalangeal joints, right ring finger, index finger, small finger, and middle finger interphalangeal joints are slightly deformed and swollen. The double hand finger flexion is limited, the wrist joint extension and flexion is slightly limited, and the bilateral knee joint flexion is slightly limited. The pain score is: interphalangeal joint: 3 points, wrist joint: 3 points, knee joint: 3 points; swelling score: interphalangeal joint: 3 points, wrist joint: 1 point, knee joint: 0 point; activity limitation score: interphalangeal joint: 3 points, wrist joint: 2 points, knee joint: 2 points; CRP: 35 mmol / L; diagnosis: rheumatoid arthritis. The patient's joints are externally applied with the traditional Chinese medicine powder prepared in Example 1, 2 hours each time, once a day. After two weeks of treatment, the score indicators are: pain score: interphalangeal joint: 2 points, wrist joint: 1 point, knee joint: 2 points; swelling score: interphalangeal joint: 1 point, wrist joint: 0 point, knee joint: 0 point; activity limitation score: interphalangeal joint: 2 points, wrist joint: 1 point, knee joint: 1 point; CRP: 15 mmol / L; after four weeks of treatment, the score indicators are: pain score: interphalangeal joint: 1 point, wrist joint: 0 point, knee joint: 0 point; swelling score: interphalangeal joint: 0 point, wrist joint: 0 point, knee joint: 0 point; activity limitation score: interphalangeal joint: 0 point, wrist joint: 0 point, knee joint: 0 point; CRP: 7 mmol / L.

[0078] Case 2: Li, female, 40 years old, because "repeated bilateral interphalangeal joint pain for more than 10 years." For the complaint to the clinic, the patient complained that after washing with cold water for a long time, she had recurrent joint pain for more than 10 years. The main symptom was bilateral interphalangeal joint pain, which was more obvious when it was cold or the weather changed, and was relieved when it was warm. She took medicine every time she had unbearable pain, mainly non-steroidal anti-inflammatory analgesic drugs, which could relieve symptoms after taking medicine. But often recurrent. Later the symptoms gradually worsened, with severe swelling of the fingers, which needed to be moved for about thirty minutes to relieve the pain. The bilateral interphalangeal joint pain was severe, and occasionally had joint swelling pain. The left middle finger and ring finger interphalangeal joint, right hand ring finger interphalangeal joint was slightly deformed, and the swelling was obvious. The flexion of the fingers was limited. The pain score was 3 points; the swelling score was 2 points; the activity limitation score was 3 points; the CRP was 31 mmol / L. Diagnosis: rheumatoid arthritis. The patient was given external application of the traditional Chinese medicine powder prepared in Example 1, 2 hours each time, once a day. After two weeks of treatment, the scores were: pain score: 2 points; swelling score: 1 point; activity limitation score: 2 points; CRP: 19 mmol / L; after four weeks of treatment, the scores were: pain score: 0 points; swelling score: 0 points; activity limitation score: 0 points; CRP: 5.5 mmol / L.

[0079] Case 3: Sun, male, 65 years old, because "repeated joint pain for more than 20 years, aggravated for 1 day." For the chief complaint to the clinic, the patient complained of no obvious cause for more than 20 years of repeated joint pain. Initially, bilateral wrist and ankle joint pain was the main symptom, and then interphalangeal joint pain occurred. The pain was more obvious when it was cold or the weather changed. The above-mentioned joints were swollen to varying degrees, and the morning stiffness was obvious. After the disease, the patient went to the local hospital for treatment, and was diagnosed with rheumatoid arthritis. He was treated with sulfasalazine, and the symptoms were relieved. After the symptoms improved, he did not continue to take the medicine. Today, the weather changed, and the above-mentioned symptoms aggravated again. The pain was slightly relieved after hot compress. The bilateral interphalangeal joints, wrist joints and ankle joints were all painful, and occasionally had joint swelling pain. There was no obvious deformation of the bilateral fingers, but the swelling was obvious. The flexion of the fingers was limited, the wrist joint extension and flexion was slightly limited, and the bilateral ankle joint activity was not limited. Pain score: interphalangeal joint: 3 points, wrist joint: 3 points, ankle joint: 2 points; swelling score: interphalangeal joint: 3 points, wrist joint: 1 point, ankle joint: 1 point; activity limitation score: interphalangeal joint: 3 points, wrist joint: 2 points, ankle joint: 1 point; CRP: 27 mmol / L; The patient was given external application of the traditional Chinese medicine powder prepared in Example 1, 2 hours each time, once a day. After two weeks of treatment, the scores were: pain score: interphalangeal joint: 2 points, wrist joint: 1 point, ankle joint: 1 point; swelling score: interphalangeal joint: 1 point, wrist joint: 0 point, ankle joint: 0 point; activity limitation score: interphalangeal joint: 1 point, wrist joint: 1 point, ankle joint: 1 point; CRP: 9 mmol / L; After four weeks of treatment, the scores were: pain score: interphalangeal joint: 1 point, wrist joint: 0 point, ankle joint: 0 point; swelling score: interphalangeal joint: 0 point, wrist joint: 0 point, ankle joint: 0 point; activity limitation score: interphalangeal joint: 0 point, wrist joint: 0 point, ankle joint: 0 point; CRP: 3.5 mmol / L.

[0080] The above only describes the preferred embodiments of the present application and is not intended to limit the present application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A traditional Chinese medicine composition for treating rheumatoid arthritis, characterized in that, The Chinese medicinal materials are prepared by the following weight parts: 23-27 parts of Angelica pubescens, 4-6 parts of Carthamus tinctorius, 9-11 parts of Boswellia carterii, 7-9 parts of Ligusticum chuanxiong, 18-22 parts of Ramulus cinnamomi, 23-27 parts of Achyranthes bidentata, 23-27 parts of Schizonepeta tenuifolia, 7-9 parts of Zanthoxylum bungeanum, 12-14 parts of Commiphora myrrha, 23-27 parts of Alpinia oxyphylla, 23-27 parts of Chaenomeles speciosa, 14-16 parts of Saposhnikovia divaricata, 23-27 parts of Notopterygium incisum, 18-22 parts of Clematis finetiana, and 23-27 parts of Sedi Herba.

2. The Chinese medicine composition for treating rheumatoid arthritis according to claim 1, characterized in that, The Chinese medicinal materials are prepared by the following weight parts: 25 parts of Angelica pubescens, 5 parts of Carthamus tinctorius, 10 parts of Boswellia carterii, 8 parts of Ligusticum chuanxiong, 20 parts of Ramulus cinnamomi, 25 parts of Achyranthes bidentata, 25 parts of Schizonepeta tenuifolia, 8 parts of Zanthoxylum bungeanum, 13 parts of Commiphora myrrha, 25 parts of Alpinia oxyphylla, 25 parts of Chaenomeles speciosa, 15 parts of Saposhnikovia divaricata, 25 parts of Notopterygium incisum, 20 parts of Clematis finetiana, and 25 parts of Sedi Herba.

3. The Chinese medicine composition for treating rheumatoid arthritis according to claim 1, characterized in that, The Boswellia carterii is acetic Boswellia carterii.

4. The Chinese medicine composition for treating rheumatoid arthritis according to claim 1, characterized in that, The Commiphora myrrha is acetic Commiphora myrrha.

5. A Chinese medicine powder for treating rheumatoid arthritis, characterized in that, The Chinese medicinal powder is prepared from the Chinese medicinal composition for treating rheumatoid arthritis according to claim 1, and the preparation method of the Chinese medicinal powder comprises the following steps: taking Angelica pubescens, Carthamus tinctorius, Boswellia carterii, Ligusticum chuanxiong, Ramulus cinnamomi, Achyranthes bidentata, Schizonepeta tenuifolia, Zanthoxylum bungeanum, Commiphora myrrha, Alpinia oxyphylla, Chaenomeles speciosa, Saposhnikovia divaricata, Notopterygium incisum, Clematis finetiana, and Sedi Herba, and grinding them into powder.

6. The Chinese medicinal composition for treating rheumatoid arthritis according to any one of claims 1-2 in the preparation of a medicament for treating rheumatoid arthritis.