An emergency portable blood purification system

Abstract

This invention discloses an emergency portable blood purification system, comprising a hemodialyzer for dialysis of a patient's blood, an emergency supply box detachably connected to the hemodialyzer, and a communicator connected to a telemedicine center. The emergency supply box contains a fixed amount of various raw materials for supplying the dialysate to the hemodialyzer. The communicator is used to send the current dialysis status parameters of the hemodialyzer to the telemedicine center and to receive prescriptions from the telemedicine center; wherein the prescription includes at least the proportions of the various raw materials stored in the emergency supply box. The emergency portable blood purification system provided by this invention enables convenient and timely hemodialysis treatment for patients, reduces dependence on the treatment environment, is easy to carry and assemble, and increases the maximum dialysis dose, achieving targeted and personalized treatment for patients.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to an emergency portable blood purification system. Background Technology

[0002] Currently, patients suffering from uremia require long-term hemodialysis treatment. Hemodialysis involves simultaneously introducing the patient's blood and dialysate into a dialyzer. Using the semi-permeable membrane of the dialyzer (artificial kidney), excess toxins and water accumulated in the blood are removed, while bases are replenished to correct acidosis, adjust electrolyte imbalances, and replace the excretory function of the kidneys. Hemodialysis can also be applied to end-stage renal disease, poisoning, biochemical trauma, and other diseases, providing dialysis filtration, detoxification, treatment, maintaining the body's acid-base and ion balance, and reducing the levels of various toxins in the body.

[0003] In existing technologies, patients with renal function replacement needs usually use outpatient dialysis, emergency dialysis, or CRRT (continuous renal replacement therapy). Patients need to have vascular access prepared in advance, and after arriving at the hospital, professional doctors will carry out treatment according to the prescription.

[0004] However, traditional dialysis treatment methods are only suitable for patients with stable conditions and slow disease progression. For patients with sudden illness, treatment can only be carried out after they are transferred from the accident site to the hospital. Timely treatment cannot be provided at the accident site, which can easily lead to the condition worsening during the transfer. In addition, traditional treatment equipment is installed in hospital wards. The equipment is expensive and bulky, difficult to install and maintain, and basically cannot be moved, making it difficult to access at any time. Furthermore, in traditional outpatient and emergency models, patients, consumables, equipment, and doctors must be present simultaneously, leading to a strong dependence on medical care, facilities, transportation, and timeliness. In situations involving mass casualties, such as mass heatstroke, even if emergency dialysis treatment can be performed using miniaturized dialyzers in existing technologies, the dialysis dose of these miniaturized dialyzers is very limited, typically purifying only a few hundred milliliters of blood, often insufficient to save critically ill patients. On the other hand, different patients have different conditions and therefore different needs for dialysis treatment, such as dialysis dose and dialysate composition. In addition to dialysis, some patients may require other treatments simultaneously. Existing miniaturized dialyzers can only provide uniform and simplified dialysis treatment, making it difficult to provide targeted and personalized treatment to different patients at the scene of an accident, resulting in a failure to improve the patients' conditions and potentially even worsening them.

[0005] Therefore, how to conveniently and promptly perform hemodialysis treatment on patients, reduce dependence on the treatment environment, make it easy to carry and disassemble, and increase the maximum dialysis dose to achieve targeted and personalized treatment for patients are technical problems faced by those skilled in the art. Summary of the Invention

[0006] The purpose of this invention is to provide an emergency portable blood purification system that can conveniently and promptly perform hemodialysis treatment on patients, reduce dependence on the treatment environment, and is easy to carry and disassemble, while increasing the maximum dialysis dose and achieving targeted and personalized treatment for patients.

[0007] To address the aforementioned technical problems, this invention provides an emergency portable blood purification system, comprising a hemodialyzer for dialyzing a patient's blood, an emergency supply box detachably connected to the hemodialyzer, and a communicator connected to a remote medical center. The emergency supply box contains a fixed amount of various raw materials for supplying the dialysis fluid required by the hemodialyzer. The communicator is used to send the current dialysis status parameters of the hemodialyzer to the remote medical center and to receive prescriptions from the remote medical center.

[0008] The prescription includes at least the proportions of the various raw materials stored in the emergency supply box.

[0009] Preferably, the hemodialyzer includes a main housing, a dialysis chamber opened within the main housing, and a dialysis module built into the dialysis chamber. The dialysis chamber is filled with dialysate. One end of the dialysis module is used to communicate with the patient's arterial blood vessels, and the other end of the dialysis module is used to communicate with the patient's venous blood vessels.

[0010] Preferably, the hemodialysis machine further includes an arterial assembly disposed at one end of the main housing and a venous assembly disposed at the other end of the main housing. The arterial assembly is used to introduce the patient's arterial blood into the fiber tubes of the dialysis module, and the venous assembly is used to draw the blood that has passed through the dialysis module out into the patient's vein.

[0011] Preferably, the arterial assembly includes an arterial housing, an arterial lumen formed within the arterial housing, and an arterial interface formed on the arterial housing and communicating with the arterial lumen. The arterial lumen is connected to one end of each fiber tube of the dialysis module, and the arterial interface is used to communicate with the patient's arterial blood vessels.

[0012] Preferably, the arterial lumen is covered with an elastic pressure membrane for pressurizing the arterial blood entering the arterial lumen, and a one-way valve is provided in the arterial interface to prevent the blood in the arterial lumen from flowing back into the patient's arterial blood vessels.

[0013] Preferably, it also includes a booster pump, the actuator of which is poweredly connected to the outer wall of the elastic pressure diaphragm to repeatedly press the elastic pressure diaphragm.

[0014] Preferably, the vein assembly includes a vein housing, a vein lumen formed within the vein housing, and a vein interface formed on the vein housing and communicating with the vein lumen. The vein lumen is connected to the other end of each fiber tube of the dialysis module, and the vein interface is used to communicate with the patient's vein.

[0015] Preferably, a filter screen is provided in the venous lumen to intercept blood clots formed in the blood, and a one-way valve is provided in the venous interface to prevent blood in the patient's vein from flowing back into the venous lumen.

[0016] Preferably, a waste liquid chamber is further provided inside the main housing, and the waste liquid chamber is connected to the end of the dialysis chamber near the arterial assembly; a waste liquid switch is provided on the arterial housing for controlling the on / off state of the waste liquid chamber and the dialysis chamber.

[0017] Preferably, the main housing is further provided with a fluid replenishment chamber, which stores a preset amount of dialysate, and the fluid replenishment chamber is connected to the end of the dialysis chamber near the vein assembly; the vein housing is provided with a fluid replenishment switch for controlling the on / off state of the fluid replenishment chamber and the dialysis chamber.

[0018] Preferably, the main housing is provided with a first interface, which is connected to the end of the dialysis chamber near the artery assembly. The first interface is used to connect to external equipment to discharge waste liquid.

[0019] Preferably, the system further includes a quantitative discharge tank, one end of which is provided with a first female connector and the other end of which is provided with a first male connector. The first female connector is used to form a detachable connection with the first interface or to cascade with the first male connector to connect two adjacent quantitative discharge tanks.

[0020] Preferably, the main housing is further provided with a second interface, which is connected to the end of the dialysis chamber near the vein assembly. The second interface is used to connect to external equipment to introduce dialysis fluid.

[0021] Preferably, the device further includes a metering container, one end of which is provided with a second female connector and the other end of which is provided with a second male connector. The second female connector is used to form a detachable connection with the second interface, or to cascade with the second male connector to connect two adjacent metering containers.

[0022] Preferably, it also includes a pre-fill cleaner built into the dialysis chamber, the pre-fill cleaner storing a preset amount of cleaning fluid for cleaning the arterial interface of the arterial assembly and the venous interface of the venous assembly before dialysis.

[0023] Preferably, the pre-filled cleaner includes a tube body, a first lumen and a second lumen opened in the tube body and isolated from each other, a first piston slidably disposed in the first lumen, and a second piston slidably disposed in the second lumen. The space between the first piston and the inner wall of the first lumen is filled with compressed gas, and the space between the second piston and the inner wall of the second lumen is filled with compressed gas. The first lumen is connected to the arterial lumen of the arterial assembly, and the second lumen is connected to the venous lumen of the venous assembly.

[0024] Preferably, the dialysis module includes sealing plates distributed on opposite sides and multiple fiber tubes inserted between the sealing plates. Each sealing plate has a clearance hole in its central area, and each fiber tube is distributed around the clearance hole. The two ends of the pre-filled cleaner are respectively installed in the corresponding clearance holes.

[0025] The emergency portable blood purification system provided by this invention mainly includes a hemodialysis machine, an emergency supply box, and a communicator. The hemodialysis machine is primarily used for dialysis treatment of a patient's blood, providing emergency dialysis therapy. The emergency supply box is mounted on the hemodialysis machine and is detachably connected, allowing for easy disassembly and installation. The emergency supply box stores a certain amount of raw materials, including various types, which can be used according to a prescription or mixed in specific proportions to form specific medical supplies, such as dialysis fluid, which can be directly supplied to the hemodialysis machine to replenish the consumed dialysis fluid. The communicator maintains a signal connection with a remote medical center, enabling it to send the current dialysis status parameters of the hemodialysis machine (related to the patient's condition) to the remote medical center during on-site dialysis treatment. It can also receive prescriptions from the remote medical center after processing the received data, allowing on-site personnel to process the information on the prescription. The prescription information includes at least the proportions of the various raw materials stored in the emergency supply box, enabling on-site personnel to prepare dialysis fluid and other medical supplies on-site according to the patient's condition. Thus, the emergency portable blood purification system provided by this invention allows for on-site emergency quantitative dialysis treatment of patients with sudden illness requiring hemodialysis. If the patient's condition worsens or the dialysis time is prolonged, communication with a remote medical center can be maintained via a communicator to obtain a prescription matching the patient's current condition. Based on the prescription, dialysis fluid and other medical supplies can be specifically prepared in the emergency supply box to supplement the dialysis dosage, effectively slowing the progression of the condition and preventing it from worsening during transfer from the site to the hospital, providing buffer time for the arrival of an ambulance or site relocation. In summary, the emergency portable blood purification system provided by this invention enables convenient and timely hemodialysis treatment, reduces dependence on the treatment environment, is easy to carry and assemble, and increases the maximum dialysis dosage, achieving targeted and personalized treatment for patients. Attached Figure Description

[0026] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0027] Figure 1 This is a schematic diagram of the overall structure of a specific embodiment of the present invention.

[0028] Figure 2 This is a schematic diagram of the specific structure of a hemodialysis machine.

[0029] Figure 3 A schematic diagram of the main shell structure.

[0030] Figure 4 for Figure 3 A partial longitudinal sectional view.

[0031] Figure 5 This is a schematic diagram of the specific structure of the arterial assembly.

[0032] Figure 6 This is a schematic diagram of the specific structure of the vein assembly.

[0033] Figure 7 This is a schematic diagram of the specific structure of the dialysis module.

[0034] Figure 8 This is a structural diagram of the first interface, the second interface, the quantitative discharge tank, and the quantitative administration tank.

[0035] Figure 9 This is a longitudinal sectional view of the pre-charge cleaner.

[0036] Figure 10 This is a schematic diagram showing the flow of blood and dialysate within a hemodialysis machine.

[0037] Figure 11 The present invention provides a scenario application logic flowchart for an emergency portable blood purification system in a specific embodiment.

[0038] Figure 12 This is a product usage logic flowchart of a hemodialysis machine according to a specific embodiment of the present invention.

[0039] in, Figure 1 — Figure 12 middle:

[0040] Hemodialysis machine—1, emergency supply box—2, communicator—3, booster blood pump—4, pre-fill cleaner—5, first interface—6, quantitative drainage tank—7, second interface—8, quantitative drug delivery tank—9;

[0041] Main shell—11, dialysis chamber—12, dialysis mold bundle—13, arterial assembly—14, venous assembly—15, waste fluid chamber—16, replenishment fluid chamber—17, clamping groove—18;

[0042] Tube body—51, first cavity—52, second cavity—53, first piston—54, second piston—55;

[0043] First female connector—71, first male connector—72;

[0044] Second female connector—91, second male connector—92;

[0045] Sealing plate—131, fiber tube—132, clearance hole—133;

[0046] Artery shell—141, artery lumen—142, artery interface—143, elastic pressure membrane—144, waste liquid switch—145;

[0047] Vein housing—151, vein cavity—152, vein interface—153, filter—154, infusion switch—155. Detailed Implementation

[0048] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0049] Please refer to Figure 1 , Figure 1 This is a schematic diagram of the overall structure of a specific embodiment of the present invention.

[0050] In one specific embodiment of the present invention, the emergency portable blood purification system mainly includes a hemodialyzer 1, an emergency supply box 2, and a communicator 3.

[0051] Among them, the hemodialyzer 1 is mainly used to perform dialysis on the patient's blood for emergency dialysis treatment.

[0052] Emergency supply box 2 is installed on hemodialysis machine 1 and forms a detachable connection with it, allowing for easy disassembly and installation. Emergency supply box 2 stores a certain amount of raw materials, including various types such as dialysis water, dialysis concentrate, and ion salt powder. These materials can be used according to prescriptions or mixed in specific proportions to form specific medical supplies, such as dialysis fluid, which can be directly supplied to hemodialysis machine 1 to replenish the dialysis fluid consumed by it.

[0053] Generally, in addition to storing a certain amount of raw materials for dialysis fluid, such as sterile replacement fluid, anticoagulant, dialysis water, dialysis concentrate, and ionized salt powder, the emergency supply box 2 can also store commonly used emergency medicines and equipment, such as antibiotics, analgesics, sedatives, and respirators.

[0054] The communicator 3 is used to maintain a signal connection with the telemedicine center. During on-site dialysis treatment, it can monitor the current dialysis status parameters of the hemodialyzer 1 (related to the patient's condition) in real time and send them to the telemedicine center. It can also receive prescriptions from the telemedicine center after processing the data, allowing on-site personnel to take appropriate action based on the prescription information. Typically, the telemedicine center can be a hospital's emergency center, etc.

[0055] The prescription includes at least the proportions of various raw materials stored in Emergency Supply Box 2, enabling on-site personnel to prepare dialysis fluid and other medical supplies according to the patient's condition. Of course, depending on the patient's dialysis status, the prescription may also include other necessary medications and medical equipment, which can generally be obtained directly from Emergency Supply Box 2.

[0056] Thus, the emergency portable blood purification system provided in this embodiment allows for on-site emergency quantitative dialysis treatment using the hemodialyzer 1 when a patient suddenly falls ill and requires hemodialysis. If the condition worsens or the dialysis time is prolonged, the system can also communicate with the telemedicine center using the communicator 3 to obtain a prescription that matches the patient's current condition. Based on the prescription, the system can then specifically prepare dialysis fluid and other medical supplies in the emergency supply box 2 to supplement the dialysis dosage, effectively slow the progression of the condition, prevent the condition from worsening during the transfer from the site to the hospital, and provide buffer time for the arrival of the ambulance or site relocation.

[0057] In summary, the emergency portable blood purification system provided in this embodiment can conveniently and promptly perform hemodialysis treatment on patients, reduce dependence on the treatment environment, and is easy to carry and disassemble, while increasing the maximum dialysis dose and achieving targeted and personalized treatment for patients.

[0058] like Figure 2 As shown, Figure 2 This is a schematic diagram of the specific structure of hemodialysis machine 1.

[0059] In one alternative embodiment of the hemodialyzer 1, the hemodialyzer 1 has a split structure, mainly including a main housing 11, a dialysis chamber 12, and a dialysis module 13.

[0060] like Figure 3 , Figure 4 As shown, Figure 3 A schematic diagram of the main shell 11 is shown below. Figure 4 for Figure 3 A partial longitudinal sectional view.

[0061] The main housing 11 is the main structure of the hemodialysis machine 1, and is typically elongated cylindrical in shape. The dialysis chamber 12, located within the main housing 11, is a sealed cavity filled with a predetermined amount of dialysate, primarily used to provide the dialysis treatment environment; it is also typically cylindrical. The dialysis module 13 is installed within the dialysis chamber 12. One end of the dialysis module 13 is connected to the patient's arterial blood vessel, while the other end is connected to the patient's venous blood vessel. It is mainly used to draw arterial blood from the patient and exchange substances with the dialysate in the dialysis chamber 12 during its flow, diffusing toxic substances from the blood into the dialysate to purify the blood. The purified blood then flows back into the venous blood vessel.

[0062] like Figure 7 As shown, Figure 7 This is a schematic diagram of the specific structure of the dialysis module 13.

[0063] In one optional embodiment of the dialysis module 13, the dialysis module 13 mainly includes sealing plates 131 and fiber tubes 132. The fiber tubes 132 are the core component, being hollow tubes with a small diameter and semi-permeable membrane walls. A large number of fiber tubes 132 are typically bundled together, such as 10,000 to 15,000 tubes. Two sealing plates 131 are generally provided, distributed on opposite sides, positioned at both ends of the fiber tubes 132, respectively forming tight contact with the arterial housing 141 in the arterial assembly 14 and the venous housing 151 in the venous assembly 15, and sealing the arterial lumen 142 and venous lumen 143, respectively. Specifically, both ends of each fiber tube 132 are inserted into the sealing plates 131 on both sides, fixing and connecting the fiber tubes 132, sealing the gaps between the fiber tubes 132, without affecting the conductivity of the fiber tubes 132. During hemodialysis, dialysate fills the gaps between each fiber tube 132. Blood flows inside each fiber tube 132, while dialysate flows outside each fiber tube 132. The two flow in opposite directions. Toxins in the blood are removed through the principle of semipermeable membrane, and excess water in the blood is removed through ultrafiltration and osmosis.

[0064] To facilitate blood extraction and return, this embodiment includes an arterial assembly 14 and a venous assembly 15. The arterial assembly 14 is located at one end of the main housing 11 and is primarily used to connect to the patient's arterial blood vessels, allowing arterial blood to be drawn into the main housing 11 and then into the fiber tubes 132 of the dialysis module 13. The venous assembly 15 is located at the other end of the main housing 11 and is primarily used to extract and return blood after dialysis via the dialysis module 13 to the patient's venous blood vessels.

[0065] like Figure 5 As shown, Figure 5 This is a schematic diagram of the specific structure of the arterial assembly 14.

[0066] In one alternative embodiment of the arterial assembly 14, the arterial assembly 14 mainly includes an arterial housing 141, an arterial cavity 142, and an arterial interface 143. The arterial housing 141 is the main structure of the arterial assembly 14, its shape matching that of the main housing 11, such as a curved triangle, and is typically plate-shaped, fastened to one end face of the main housing 11. The arterial cavity 142 is located within the arterial housing 141 and is mainly used to temporarily store a certain amount of arterial blood. It is typically circular, and its size is comparable to that of the sealing plate 131 in the dialysis module 13. It can temporarily store a certain amount of arterial blood between the cavity wall and the sealing plate 131. Simultaneously, the sealing plate 131 seals both ends of the dialysis cavity 12, preventing blood from the arterial cavity 142 from entering the dialysis cavity 12 and mixing with the dialysate, ensuring that blood can only enter one end of each fiber tube 132 exposed on the sealing plate 131. The arterial interface 143 is located on the arterial housing 141, typically on its side wall, and communicates with the arterial lumen 142 inside the housing. It is primarily used to connect to the patient's arterial vessels. Generally, an arterial fistula needle is installed in the arterial interface 143 for easy connection to the patient's arterial vessels. With this configuration, the patient's arterial blood can enter the arterial lumen 142 through the arterial interface 143 and then flow into each of the fiber optic tubes 132.

[0067] Furthermore, due to the physiological pressure difference between arteries and veins in the human body, when the arterial assembly 14 is connected to an artery and the venous assembly 15 is connected to a vein, blood can naturally flow through the dialysis module 13 under the influence of this physiological pressure difference. However, for some patients with low blood volume or insufficient blood flow, blood flow may be obstructed. To address this, this embodiment also adds an elastic pressure membrane 144 to the arterial assembly 14. The elastic pressure membrane 144 covers the arterial lumen 142, acting as one side wall of the arterial lumen 142, and is elastic, capable of elastic expansion and contraction. When the elastic pressure membrane 144 is pressed, a certain pressure is applied to the arterial lumen 142. Since a certain amount of blood is temporarily stored in the arterial lumen 142, the blood can be pressurized, allowing it to flow smoothly through the dialysis module 13.

[0068] Furthermore, to prevent pressurized blood from flowing back from the arterial interface 143 into the patient's arterial blood vessels, this embodiment also includes a one-way valve within the arterial interface 143. Specifically, this one-way valve functions like a one-way valve, allowing blood to flow in only one direction, from the arterial blood vessels into the arterial lumen 142, and preventing reverse flow.

[0069] Furthermore, considering that patients with severe conditions may require prolonged dialysis treatment and frequent blood pressurization, a booster pump 4 is added in this embodiment. Specifically, the actuator of the booster pump 4 is dynamically connected to the outer wall of the elastic pressure diaphragm 144, enabling repeated pressing of the outer wall of the elastic pressure diaphragm 144 at a certain frequency, thereby continuously pressurizing the blood. Generally, the booster pump 4 can be a peristaltic pump or the like, capable of pressurizing the arterial cavity 142 through hydraulic pressure, or by driving the piston rod of a micro-cylinder to extend and retract, thereby repeatedly pressing the elastic pressure diaphragm 144. Simultaneously, the booster pump 4 can be designed with a battery compartment for battery power, avoiding cable power supply, thus minimizing structural size and weight, and making it easy to carry and use. Of course, the elastic compression membrane 144 can also be replaced by pressure-increasing components such as elastic balloons and plungers. Correspondingly, the actuator of the booster pump 4 can repeatedly squeeze the elastic balloon or repeatedly push and pull the plunger at a certain frequency, which can also achieve the effect of pressurizing the arterial cavity 142.

[0070] like Figure 6 As shown, Figure 6 This is a schematic diagram of the specific structure of the vein assembly 15.

[0071] Similarly, in one optional embodiment of the vein assembly 15, the vein assembly 15 mainly includes a vein housing 151, a vein lumen 152, and a vein interface 153. The vein housing 151 is the main structure of the vein assembly 15, its shape matching that of the main housing 11, such as a curved triangle, and is typically plate-shaped, fastened to the other end face of the main housing 11, and aligned with the aforementioned arterial housing 141. The vein lumen 152 is located within the vein housing 151 and is mainly used to temporarily store a certain amount of purified blood. It is typically circular, and its size is comparable to that of the sealing plate 131 in the dialysis module 13. It can temporarily store a certain amount of purified blood between the lumen wall and the sealing plate 131, while the sealing plate 131 seals both ends of the dialysis chamber 12, preventing blood in the vein lumen 152 from entering the dialysis chamber 12 and mixing with the dialysate. The venous interface 153 is located on the venous housing 151, usually on the side wall of the venous housing 151, and is connected to the venous lumen 152 inside the venous housing 151. It is mainly used to connect with the patient's venous blood vessels.

[0072] Typically, a venous fistula needle is installed in the venous interface 153 to facilitate connection with the patient's venous blood vessels. With this configuration, purified blood flows out from the other end of the fiber optic tube 132 and enters the venous lumen 152, then flows back into the patient's venous blood vessels through the venous interface 153.

[0073] Furthermore, considering the possibility of blood clots forming in the patient's blood, in order to prevent blood clots from flowing back into the patient's veins, this embodiment also provides a filter 154 in the vein lumen 152 to physically intercept the blood and remove blood clots from the blood.

[0074] Furthermore, to prevent blood from flowing back into the venous lumen 152 from the patient's vein, this embodiment also includes a one-way valve within the venous interface 153. Specifically, this one-way valve functions like a one-way valve, allowing blood to flow in only one direction, from the venous lumen 152 into the vein, while preventing reverse flow.

[0075] In addition, to facilitate the collection of consumed dialysate, this embodiment also includes a waste fluid chamber 16 within the main housing 11. Specifically, the waste fluid chamber 16 is typically located within the main housing 11 on one side of the dialysis chamber 12, maintaining the same length as the dialysis chamber 12, and is usually cylindrical. The opening of the waste fluid chamber 16 is also connected to one end sidewall of the dialysis chamber 12, specifically to the end sidewall of the dialysis chamber 12 near the arterial assembly 14. Correspondingly, this embodiment also includes a waste fluid switch 145 on the arterial housing 141 to control the opening and closing state between the opening of the waste fluid chamber 16 and the sidewall opening of the dialysis chamber 12. Specifically, the waste fluid switch 145 can be a control valve or similar component, allowing for convenient adjustment of the opening degree.

[0076] Meanwhile, considering that the dialysis chamber 12 is usually pre-filled with a certain amount of dialysate, but the dialysate may be insufficient during long dialysis treatments, this embodiment provides a refill chamber 17 within the main housing 11. Specifically, the refill chamber 17 is typically located on the other side of the dialysis chamber 12 within the main housing 11, maintaining the same length as the dialysis chamber 12, and is usually cylindrical. The opening of the refill chamber 17 also communicates with the other end sidewall of the dialysis chamber 12, specifically with the end sidewall of the dialysis chamber 12 near the venous assembly 15. Correspondingly, this embodiment also provides a refill switch 155 on the venous housing 151 to control the opening and closing state between the opening of the refill chamber 17 and the sidewall opening of the dialysis chamber 12. Specifically, the refill switch 155 can be a control valve or similar component, allowing for convenient adjustment of the opening degree.

[0077] With this configuration, when the replenishment switch 155 and the waste liquid switch 145 are turned on, the dialysate stored in the replenishment chamber 17 can automatically flow into the dialysis chamber 12 under the action of pressure difference, and then enter the waste liquid chamber 16 after the dialysis operation is completed. Of course, the replenishment switch 155 and the waste liquid switch 145 can also be disassembled so that the replenishment chamber 17 can be directly connected to external equipment (such as the emergency supply box 2), and the same applies to the waste liquid chamber 16.

[0078] like Figure 8 As shown, Figure 8 This is a schematic diagram of the structure of the first interface 6, the second interface 8, the quantitative discharge tank 7, and the quantitative drug delivery tank 9.

[0079] Furthermore, if the waste liquid chamber 16 is not installed on the main housing 11, a first interface 6 can be provided on the main housing 11 to facilitate the discharge of waste liquid. This first interface 6 can be connected to external equipment to directly discharge waste liquid to the external equipment. Of course, similar to the waste liquid chamber 16, the first interface 6 needs to be connected to one end sidewall of the dialysis chamber 12, specifically to the end sidewall of the dialysis chamber 12 near the arterial assembly 14.

[0080] Furthermore, to facilitate the collection of waste liquid discharged from the first interface 6, a quantitative discharge tank 7 is added in this embodiment. Specifically, the quantitative discharge tank 7 is a standardized product, such as having a volume of 100mL, and is a vacuum slow-release low-pressure tank, capable of providing transmembrane pressure difference and quantitative ultrafiltration. Simultaneously, one end of the quantitative discharge tank 7 is provided with a first female connector 71, allowing for a detachable connection with the first interface 6, such as a threaded connection or a snap-fit ​​connection, facilitating easy installation on or removal from the main housing 11. Moreover, to enable the simultaneous use of multiple quantitative discharge tanks 7 and increase waste liquid capacity, this embodiment also provides a first male connector 72 at the other end of the quantitative discharge tank 7. This first male connector 72 can cascade with the first female connector 71 (also a detachable connection method) to connect adjacent quantitative discharge tanks 7 end-to-end, thus allowing multiple quantitative discharge tanks 7 to be cascaded sequentially, thereby significantly increasing the waste liquid capacity.

[0081] Similarly, to facilitate the introduction of dialysate into the dialysis chamber 17, this embodiment also provides a second interface 8 on the main housing 11, which is connected to an external drug delivery device so that dialysate can be directly introduced into the dialysis chamber 17 through the external drug delivery device. Of course, similar to the fluid replenishment chamber 17, the second interface 8 needs to be connected to the other end sidewall of the dialysis chamber 12, specifically to the end sidewall of the dialysis chamber 12 near the venous assembly 15.

[0082] Furthermore, to facilitate the introduction of dialysate into the dialysis chamber 12 via the second interface 8, a quantitative drug delivery container 9 is added in this embodiment. Specifically, this quantitative drug delivery container 9 is a standardized product, such as having a volume of 100 mL, and is internally low-pressure or pressureless. Its formulation can be pre-adjusted according to different task risks to provide quantitative dialysate or transmembrane replacement and rapid transmembrane release of small and medium-sized molecule drugs for treatment. Simultaneously, one end of the quantitative drug delivery container 9 is provided with a second female connector 91 to form a detachable connection with the second interface 8, such as a threaded connection or a snap-fit ​​connection, allowing for easy installation on or removal from the main housing 11. Moreover, to enable the simultaneous use of multiple quantitative drug delivery containers 9 and increase the treatment dosage, this embodiment also provides a second male connector 92 at the other end of the quantitative drug delivery container 9. The second male connector 92 can be cascaded with the second female connector 91 (also a detachable connection method) to connect two adjacent quantitative dosing canisters 9 end to end, thus enabling multiple quantitative dosing canisters 9 to be cascaded in sequence, thereby significantly increasing the dosage.

[0083] To facilitate maintaining the stable position of the arterial fistula needle in the arterial interface 143 and the venous fistula needle in the venous interface 153, this embodiment also provides a clamping groove 18 on the side wall of the main housing 11 to clamp the arterial fistula needle and the venous fistula needle through the clamping groove 18.

[0084] Considering that the arterial interface 143 in the arterial assembly 14 needs to be connected to the patient's arterial blood vessels, and the venous interface 153 in the venous assembly 15 needs to be connected to the patient's venous blood vessels, in order to ensure the cleanliness of the equipment and prevent bacteria, dust, and other harmful substances on the arterial interface 143 or venous interface 153 from entering the patient's blood vessels, a pre-filling cleaner 5 is added in this embodiment. This pre-filling cleaner 5 is built into the dialysis chamber 12 and is mainly used to discharge a portion of the pre-filled cleaning fluid through the principle of pressure loss expansion before the arterial interface 143 and venous interface 153 are connected to the patient's blood vessels, thereby achieving the effect of pre-cleaning the arterial interface 143 and venous interface 153.

[0085] like Figure 9 , Figure 10 As shown, Figure 9 This is a longitudinal sectional view of the pre-charge cleaner 5. Figure 10 This is a schematic diagram of the flow of blood and dialysate within hemodialysis unit 1 (solid lines represent blood, and dashed lines represent dialysate).

[0086] Specifically, the pre-filled cleaner 5 is generally cylindrical, mainly comprising a tube body 51, a first cavity 52, a second cavity 53, a first piston 54, and a second piston 55. The tube body 51 is the main structure of the pre-filled cleaner 5, specifically a hollow cylindrical tube. The first cavity 52 is located at one axial end of the tube body 51, and the second cavity 53 is located at the other axial end of the tube body 51; the two are isolated from each other by baffles or other components. The first piston 54 is embedded in the first cavity 52 and can slide within it. The second piston 55 is embedded in the second cavity 53 and can slide within it. Simultaneously, the first piston 54 and the baffle form a cylindrical cavity within the first cavity 52, which is pre-filled with compressed gas. Similarly, the second piston 55 and the baffle form a cylindrical cavity within the second cavity 53, which is also pre-filled with compressed gas. Furthermore, a certain amount of cleaning fluid is filled in the cavity outside the first piston 54 in the first cavity 52 and the cavity outside the second piston 55 in the second cavity 53 to assist in gas purging and enhance the cleaning effect.

[0087] With this configuration, since the arterial fistula needle in the arterial interface 143 and the venous fistula needle in the venous interface 153 are usually equipped with clamps, they maintain a sealed state when not in use, thereby maintaining a certain high pressure in the arterial lumen 142 and venous lumen 152 within the main housing 11. This high pressure keeps the first piston 54 and the second piston 55 in a stable position. When needed, the clamps on the arterial fistula needle and the venous fistula needle are removed simultaneously. At this time, both the arterial lumen 142 and the venous lumen 152 are depressurized, and the compressed gas in the first lumen 52 and the second lumen 53 expands due to depressurization, which in turn pushes the first piston 54 and the second piston 55 to their respective positions. 54. The second piston 55 is pushed outward (finally stopping at the outer end of the first lumen 52 and the second lumen 53, or stopping in the relief hole 133), thereby venting the pre-filled cleaning fluid in the first lumen 52 and the second lumen 53, as well as the gas in the arterial lumen 142 and the venous lumen 152, to the outside. The gas is then discharged to the outside through the arterial lumen 142 and the arterial interface 143, and the venous lumen 152 and the venous interface 153, respectively, thus realizing the depressurization and venting operation and the cleaning operation (including gas blowing and cleaning with cleaning fluid) of the arterial interface 143 and the arterial fistula needle, and the venous interface 153 and the venous fistula needle.

[0088] In addition, to minimize the space occupied by the pre-filled cleaner 5 in the dialysis chamber 12 and avoid interfering with the installation of the dialysis module 13 in the dialysis chamber 12, in this embodiment, the dialysis module 13 is specifically a hollow structure, that is, a clearance hole 133 is provided on both sides of the sealing plate 131, and each fiber tube 132 is arranged in a ring around the clearance hole 133, thereby leaving a cylindrical cavity in the central area of ​​each fiber tube 132, and the pre-filled cleaner 5 can be installed in the cylindrical cavity. The two ends of the tube body 51 of the pre-filled cleaner 5 are respectively installed in the clearance holes 133 of the sealing plate 131 on both sides to achieve positioning connection.

[0089] In one optional embodiment of the emergency supply box 2, to facilitate the installation and removal of the emergency supply box 2 on the hemodialysis machine 1, the emergency supply box 2 can be threadedly connected to the main housing 11 of the hemodialysis machine 1 using fasteners such as bolts, screws, and I-beams, or it can be locked to the main housing 11 of the hemodialysis machine 1 using snap-fit ​​components such as clips and slots. Of course, if necessary, the emergency supply box 2 can also be directly fixedly connected to the main housing 11 of the hemodialysis machine 1, such as by welding.

[0090] In one optional embodiment of the communicator 3, the communicator 3 can specifically adopt wireless communication devices such as WIFI, 4G, and 5G, and can also be configured with components such as a screen, printer, and interactive panel. It can not only send the real-time monitored current dialysis status parameters of the hemodialysis machine 1 to the remote medical center, but also enable on-site personnel and patients to communicate with the remote medical center via audio and video, and send information such as the patient's condition to the remote medical center so that the remote medical center can promptly correct and supplement the content of the prescription, and at the same time realize operations such as printing prescriptions.

[0091] like Figure 11 , Figure 12 As shown, Figure 11 This invention provides a scenario application logic flowchart for an emergency portable blood purification system according to a specific embodiment. Figure 12 The present invention provides a product usage logic flowchart for a hemodialyzer 1 in a specific embodiment.

[0092] In summary, the emergency portable blood purification system provided by this invention not only enables convenient and timely hemodialysis treatment for patients, reducing dependence on the treatment environment, but also facilitates portability and disassembly, increases the maximum dialysis volume, and achieves targeted and personalized treatment for patients. Furthermore, through quantitative pre-treatment and follow-up prescription treatment, it meets the emergency needs of patients and ensures that subsequent treatment can continue without deviation. Moreover, the hemodialyzer 1 in the system can be used independently as an emergency product or connected with other devices to complete the entire treatment process.

[0093] The above description of the disclosed embodiments enables those skilled in the art to make or use the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. An emergency portable blood purification system, characterized in that, The device includes a hemodialyzer (1) for dialysis of a patient's blood, an emergency supply box (2) detachably connected to the hemodialyzer (1), and a communicator (3) connected to a telemedicine center. The emergency supply box (2) contains a fixed amount of various raw materials for supplying the dialysis fluid required by the hemodialyzer (1). The communicator (3) is used to send the current dialysis status parameters of the hemodialyzer (1) to the telemedicine center and to receive prescriptions from the telemedicine center. The prescription includes at least the proportions of various raw materials stored in the emergency supply box (2); The hemodialyzer (1) includes a main housing (11), a dialysis chamber (12) opened in the main housing (11), and a dialysis module (13) built into the dialysis chamber (12). The dialysis chamber (12) is filled with dialysis fluid. One end of the dialysis module (13) is used to communicate with the patient's arterial blood vessels, and the other end of the dialysis module (13) is used to communicate with the patient's venous blood vessels. The hemodialyzer (1) further includes an arterial assembly (14) disposed at one end of the main housing (11) and a venous assembly (15) disposed at the other end of the main housing (11). The arterial assembly (14) is used to introduce the patient's arterial blood into each fiber tube (132) of the dialysis module (13), and the venous assembly (15) is used to draw the blood that has passed through the dialysis module (13) out to the patient's venous blood. It also includes a pre-fill cleaner (5) built into the dialysis chamber (12), the pre-fill cleaner (5) being used to clean the arterial interface (143) of the arterial assembly (14) and the venous interface (153) of the venous assembly (15) before dialysis; The pre-charge cleaner (5) includes a tube body (51), a first cavity (52) and a second cavity (53) opened in the tube body (51) and isolated from each other, a first piston (54) slidably disposed in the first cavity (52), and a second piston (55) slidably disposed in the second cavity (53). The first piston (54) and the inner wall of the first cavity (52) are filled with compressed gas, and the second piston (55) and the inner wall of the second cavity (53) are filled with compressed gas. The first cavity (52) is connected to the arterial cavity (142) of the arterial assembly (14), and the second cavity (53) is connected to the venous cavity (152) of the venous assembly (15).

2. The emergency portable blood purification system according to claim 1, characterized in that, The arterial assembly (14) includes an arterial housing (141), an arterial lumen (142) opened in the arterial housing (141), and an arterial interface (143) opened on the arterial housing (141) and communicating with the arterial lumen (142). The arterial lumen (142) is connected to one end of each fiber tube (132) of the dialysis module (13), and the arterial interface (143) is used to communicate with the patient's arterial blood vessels.

3. The emergency portable blood purification system according to claim 1, characterized in that, The vein assembly (15) includes a vein housing (151), a vein lumen (152) opened in the vein housing (151), and a vein interface (153) opened on the vein housing (151) and communicating with the vein lumen (152). The vein lumen (152) is connected to the other end of each fiber tube (132) of the dialysis module (13), and the vein interface (153) is used to communicate with the patient's vein.

4. The emergency portable blood purification system according to claim 3, characterized in that, A filter (154) is provided in the venous cavity (152) to intercept blood clots formed in the blood, and a one-way valve is provided in the venous interface (153) to prevent blood in the patient's vein from flowing back into the venous cavity (152).

5. The emergency portable blood purification system according to claim 2, characterized in that, The main housing (11) is also provided with a waste liquid chamber (16), and the waste liquid chamber (16) is connected to the end of the dialysis chamber (12) near the arterial assembly (14); the arterial housing (141) is provided with a waste liquid switch (145) for controlling the on / off state of the waste liquid chamber (16) and the dialysis chamber (12).

6. The emergency portable blood purification system according to claim 3, characterized in that, The main housing (11) is also provided with a fluid replenishment chamber (17), which stores a preset amount of dialysis fluid, and the fluid replenishment chamber (17) is connected to the end of the dialysis chamber (12) near the vein assembly (15); the vein housing (151) is provided with a fluid replenishment switch (155) for controlling the on / off state of the fluid replenishment chamber (17) and the dialysis chamber (12).

7. The emergency portable blood purification system according to claim 1, characterized in that, The main housing (11) is provided with a first interface (6), which is connected to the end of the dialysis chamber (12) near the arterial assembly (14). The first interface (6) is used to connect to external equipment to discharge waste liquid.

8. The emergency portable blood purification system according to claim 7, characterized in that, It also includes a quantitative discharge tank (7), one end of which is provided with a first female connector (71) and the other end of which is provided with a first male connector (72). The first female connector (71) is used to form a detachable connection with the first interface (6) or to form a cascade with the first male connector (72) to connect two adjacent quantitative discharge tanks (7).

9. The emergency portable blood purification system according to claim 1, characterized in that, The main housing (11) is also provided with a second interface (8), which is connected to the end of the dialysis chamber (12) near the vein assembly (15). The second interface (8) is used to connect to external equipment to introduce dialysis fluid.

10. The emergency portable blood purification system according to claim 9, characterized in that, It also includes a metering container (9), one end of which is provided with a second female connector (91) and the other end of which is provided with a second male connector (92). The second female connector (91) is used to form a detachable connection with the second interface (8) or to form a cascade with the second male connector (92) to connect two adjacent metering containers (9).

11. The emergency portable blood purification system according to claim 1, characterized in that, The dialysis module (13) includes sealing plates (131) distributed on opposite sides and multiple fiber tubes (132) inserted between each sealing plate (131). Each sealing plate (131) has a clearance hole (133) in its central area, and each fiber tube (132) is distributed around the clearance hole (133). The two ends of the pre-filled cleaner (5) are respectively installed in the corresponding clearance holes (133).

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