β-细辛醚在改善线虫寿命以及制备缓解衰老性运动衰减药物中的应用

By using β-asarone as the active ingredient, a drug to alleviate age-related motor decline was prepared, solving the problems of unclear drug composition and high production cost in existing technologies, and achieving the effects of extending the lifespan and enhancing the motor ability of Caenorhabditis elegans.

CN118078784BActive Publication Date: 2026-07-17HUNAN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HUNAN UNIV
Filing Date
2024-01-31
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In the existing technology, the drug components used to prolong the lifespan of Caenorhabditis elegans and enhance its motor ability are unclear, and the production cost is high. There is a lack of industrialized drug preparation methods, and it cannot effectively alleviate age-related motor decline.

Method used

Using β-asarone as the active ingredient, and combining it with pharmaceutically acceptable excipients, oral or injectable formulations are prepared for the development of drugs to alleviate age-related motor decline and enhance the motility and lifespan of *C. elegans*.

Benefits of technology

β-Asauropin significantly prolongs the lifespan of Caenorhabditis elegans and enhances its motility, providing a pharmaceutically acceptable dosage form that solves the problems of unclear drug composition and high production costs in existing technologies, and achieves the effect of alleviating age-related motor decline.

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Abstract

本发明属于药物应用领域,具体涉及β‑细辛醚延长线虫寿命和缓解衰老性运动衰减中的应用。本发明研究表明,β‑细辛醚能够延长线虫寿命和缓解运动性神经衰减,可以用于开展线虫及其关联运动衰减药物的开发研究。
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