A multi-channel, automated chemical synthesis, magnetic attraction and in-situ cleaning device

Abstract

The application relates to the technical field of automatic synthesis of magnetic micro-nano materials, in particular to a multi-channel, automatic chemical synthesis, magnetic attraction and in-situ cleaning device, which comprises a bottom plate, a magnetic attraction module and an ultrasonic stirring module; the magnetic attraction module is connected with the bottom plate through a transverse displacement module, and the transverse displacement module is used for controlling the transverse movement of the magnetic attraction module; the ultrasonic stirring module is connected with the bottom plate through a longitudinal displacement module, and the longitudinal displacement module is used for controlling the longitudinal movement of the ultrasonic stirring module; the transverse displacement module comprises a transverse displacement module transverse support, a transverse displacement module guide rail and a transverse displacement module motor used for controlling the transverse movement of the transverse displacement module transverse support on the transverse displacement module guide rail; and the longitudinal displacement module comprises a longitudinal displacement module transverse support and a longitudinal displacement module longitudinal support. The application can realize efficient and stable silicon coating reaction, and can realize automatic magnetic attraction and cleaning, thereby greatly improving the production efficiency and product quality.

Description

Technical Field

[0001] This application relates to the field of automated synthesis technology of magnetic micro-nano materials, and in particular to a multi-channel, automated chemical synthesis, magnetic attraction and in-situ cleaning device. Background Technology

[0002] Magnetic micro / nanomaterials have broad application prospects in fields such as biomedicine and environmental remediation. Among these, the silicon-coating preparation of magnetic micro / nanomaterials is a key technology, as it can endow these materials with better stability, biocompatibility, and functionality. Traditional silicon-coating methods suffer from problems such as long preparation cycles, uneven product distribution, and the inability to achieve large-scale production. Therefore, developing an automated silicon-coating reaction technology has become one of the current research focuses.

[0003] Meanwhile, in the fabrication of magnetic micro / nano materials, the magnetic attraction and cleaning processes are crucial steps to ensure product quality. Traditional magnetic attraction and cleaning processes suffer from problems such as complex operation, low efficiency, and incomplete cleaning. Therefore, developing a highly automated and easy-to-operate magnetic attraction and cleaning device is essential for improving production efficiency and reducing labor costs. Summary of the Invention

[0004] This application provides a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device. This device can achieve efficient and stable silicon-coating reaction, while also enabling automated magnetic attraction and cleaning, greatly improving production efficiency and product quality.

[0005] To address the aforementioned technical problems, this application provides a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device. The device includes: a base plate and a magnetic attraction module and an ultrasonic stirring module mounted on the base plate; the magnetic attraction module is connected to the base plate via a lateral displacement module, which controls the lateral movement of the magnetic attraction module; the ultrasonic stirring module is connected to the base plate via a longitudinal displacement module, which controls the longitudinal movement of the ultrasonic stirring module; the lateral displacement module includes a lateral support, a lateral displacement module guide rail, and a lateral displacement module motor for controlling the lateral movement of the lateral support on the lateral displacement module guide rail; the longitudinal displacement module includes a lateral support and a longitudinal support, with a longitudinal displacement module guide rail mounted on the longitudinal support, and a longitudinal displacement module motor for controlling the longitudinal movement of the lateral support on the longitudinal displacement module guide rail.

[0006] In some exemplary embodiments, the longitudinal displacement module includes two longitudinal displacement module supports disposed at both ends of the base plate, and a transverse support is disposed at both ends of the two longitudinal displacement module supports; the ultrasonic stirring module is fixedly connected to the transverse support of the longitudinal displacement module; the longitudinal displacement module motor is a lifting motor, used to control the longitudinal movement of the transverse support of the longitudinal displacement module, so as to drive the ultrasonic stirring module to move longitudinally; longitudinal is the direction perpendicular to the base plate.

[0007] In some exemplary embodiments, the lateral displacement module includes two modules, which are respectively mounted on the longitudinal supports of the longitudinal displacement modules at both ends of the base plate. The lateral displacement module supports are positioned between the longitudinal supports of the longitudinal displacement modules at both ends of the base plate, and the magnetic suction module is mounted on the lateral displacement module supports. The lateral displacement module motor is a stepper motor, and the output shaft of the stepper motor is connected to a lead screw. The stepper motor controls the movement of the lead screw to control the lateral movement of the lateral displacement module supports, thereby driving the magnetic suction module to move laterally. The lateral direction is parallel to the base plate and perpendicular to the lateral supports of the longitudinal displacement modules.

[0008] In some exemplary embodiments, the ultrasonic stirring module includes multiple ultrasonic stirring units arranged sequentially along the length of the transverse support of the longitudinal displacement module. Each ultrasonic stirring unit includes a support bracket and an ultrasonic stirring paddle that penetrates the support bracket. The support bracket is fixedly connected to the transverse support of the longitudinal displacement module.

[0009] In some exemplary embodiments, the above-mentioned multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device further includes: a heating module and an inlet / outlet pipe module disposed on the base plate; the heating module includes a heating rod disposed beside the ultrasonic stirring paddle, and the heating rod is fixedly connected to the support bracket; the inlet / outlet pipe module includes an inlet pipe, an outlet pipe, and an inlet / outlet pipe placement groove; the inlet pipe and the outlet pipe are respectively disposed on both sides of the ultrasonic stirring paddle, and both the inlet pipe and the outlet pipe pass through the support bracket and are fixedly connected to the support bracket; the inlet / outlet pipe placement groove is disposed above the support bracket.

[0010] In some exemplary embodiments, the above-mentioned multi-channel, automated chemical synthesis, magnetic attraction and in-situ cleaning device further includes: a reagent addition module disposed on the base plate; the reagent addition module is used to add chemical reagents to the solvent bottle during the chemical synthesis reaction; the reagent addition module includes a reagent dropper penetrating the support bracket and a reagent addition control pump for controlling the addition of reagents.

[0011] In some exemplary embodiments, the heating module, the inlet / outlet liquid pipe module, and the reagent dispensing module are all fixedly connected to the transverse support of the longitudinal displacement module; the longitudinal displacement module controls the longitudinal movement of the transverse support of the longitudinal displacement module to drive the heating module, the inlet / outlet liquid pipe module, and the reagent dispensing module to move longitudinally.

[0012] In some exemplary embodiments, the magnetic module includes multiple annular magnets, and each annular magnet corresponds to an ultrasonic stirring unit of the ultrasonic stirring module; the annular magnets are permanent magnets with an annular angle of 180 degrees.

[0013] In some exemplary embodiments, the above-mentioned multi-channel, automated chemical synthesis, magnetic attraction and in-situ cleaning device further includes: a reagent bottle holder disposed on the base plate, the reagent bottle holder being placed below the ultrasonic stirring module, and the reagent bottle holder having multiple reagent bottle grooves, the positions of the reagent bottle grooves corresponding one-to-one with the ultrasonic stirring units of the ultrasonic stirring module.

[0014] In some exemplary embodiments, both the longitudinal displacement module motor and the lateral displacement module motor are electrically connected to the control module. The control module has built-in control software, which is used to edit the motion flow to execute different chemical reaction execution flows.

[0015] The technical solutions provided in this application have at least the following advantages.

[0016] This application provides a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device. The device includes: a base plate and a magnetic attraction module and an ultrasonic stirring module disposed on the base plate; the magnetic attraction module is connected to the base plate via a lateral displacement module, which controls the lateral movement of the magnetic attraction module; the ultrasonic stirring module is connected to the base plate via a longitudinal displacement module, which controls the longitudinal movement of the ultrasonic stirring module; the lateral displacement module includes a lateral support, a lateral displacement module guide rail, and a lateral displacement module motor for controlling the lateral movement of the lateral support on the lateral displacement module guide rail; the longitudinal displacement module includes a lateral support and a longitudinal support, with a longitudinal displacement module guide rail disposed on the longitudinal support, and a longitudinal displacement module motor for controlling the longitudinal movement of the lateral support on the longitudinal displacement module guide rail.

[0017] This application addresses numerous problems existing in the integration of existing silicon-coated magnetic micro / nano material preparation devices with advanced manufacturing platforms such as intelligent and automated experimental platforms. It proposes a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device. By integrating a magnetic attraction module, an ultrasonic stirring module, a heating module, and a cleaning module, intelligent and automated experimental preparation is achieved. This eliminates the need to separate synthesis and cleaning processes, and also eliminates the need for multiple transfers of cleaning reagent bottles after adsorbing the magnetic rod, reducing manual operations and significantly improving experimental efficiency. Furthermore, the experimental equipment presented in this application has been experimentally verified and demonstrates excellent operational results. Attached Figure Description

[0018] One or more embodiments are illustrated by way of example with reference to the accompanying drawings. These illustrations do not constitute a limitation on the embodiments, and unless otherwise stated, the figures in the drawings are not to be limited by scale.

[0019] Figure 1 This is a three-dimensional structural schematic diagram of a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device provided in an embodiment of this application.

[0020] Figure 2 A three-dimensional structural schematic diagram of a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device provided in another embodiment of this application.

[0021] Figure 3 This is a front view of a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning apparatus provided in an embodiment of this application.

[0022] Figure 4 This is a side view of a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning apparatus provided in an embodiment of this application.

[0023] Figure 5 This is a top view of a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning apparatus provided in an embodiment of this application.

[0024] Figure 6 This is a schematic diagram of an ultrasonic stirring impeller, heating module, and liquid inlet / outlet module provided in an embodiment of this application.

[0025] Figure 7 A schematic diagram of the bottom lateral displacement module of a multi-channel, automated chemical synthesis, magnetic attraction and in-situ cleaning device provided in an embodiment of this application.

[0026] Among them, 1 is the base plate, 2 is the longitudinal displacement module, 201 is the longitudinal support of the longitudinal displacement module, 202 is the transverse support of the longitudinal displacement module, 203 is the guide rail of the longitudinal displacement module, 204 is the motor of the longitudinal displacement module, 3 is the transverse displacement module, 301 is the transverse support of the transverse displacement module, 302 is the guide rail of the transverse displacement module, 303 is the motor of the transverse displacement module, 4 is the reagent bottle holder, 401 is the reagent bottle groove, 5 is the magnetic suction module, 501 is the ring magnet, 6 is the ultrasonic stirring module, 601 is the ultrasonic stirring unit, 602 is the bearing support, 603 is the ultrasonic stirring paddle, 604 is the ultrasonic stirring motor, 7 is the heating module, 701 is the heating rod, 8 is the liquid inlet / outlet module, 801 is the liquid inlet pipe, 802 is the liquid outlet pipe, 803 is the liquid inlet / outlet pipe placement slot, 9 is the reagent adding module, 901 is the reagent adding control pump, and 10 is the motor controller. Detailed Implementation

[0027] As the background technology shows, traditional magnetic attraction and cleaning processes suffer from problems such as complex operation, low efficiency, and incomplete cleaning. Specifically, existing silicon-coated fabrication devices for magnetic micro / nano materials mainly have the following problems:

[0028] (1) In the current methods for preparing magnetic micro and nano materials, most of the synthesis and cleaning steps are carried out separately. First, the magnetic beads are coated with silicon and then transferred to a magnetic cleaning station for magnetic attraction and cleaning. This increases the number of transfer steps and is not conducive to the integration of intelligent and automated experimental schemes.

[0029] (2) At present, magnetic attraction is mostly done by magnetic rods. Magnetic micro-nano materials such as magnetic beads are adsorbed onto the magnetic rods and then transferred to a reagent bottle containing a clean cleaning solution by the magnetic rods for cleaning. Since the magnetic beads need to be cleaned multiple times, the reagent bottle needs to be transferred multiple times after being adsorbed by the magnetic rods to complete the cleaning work.

[0030] (3) Currently, most experiments on the preparation of magnetic micro / nano materials such as magnetic beads are carried out in a single, sequential manner, requiring manual execution of multiple steps, resulting in low experimental efficiency. This application proposes a multi-channel, automated approach that enables efficient and high-throughput large-volume synthesis experiments.

[0031] To address the aforementioned technical problems, this application provides a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device. The device includes: a base plate and a magnetic attraction module and an ultrasonic stirring module mounted on the base plate; the magnetic attraction module is connected to the base plate via a lateral displacement module, which controls the lateral movement of the magnetic attraction module; the ultrasonic stirring module is connected to the base plate via a longitudinal displacement module, which controls the longitudinal movement of the ultrasonic stirring module; the lateral displacement module includes a lateral support, a lateral displacement module guide rail, and a lateral displacement module motor for controlling the lateral movement of the lateral support on the lateral displacement module guide rail; the longitudinal displacement module includes a lateral support and a longitudinal support, with a longitudinal displacement module guide rail mounted on the longitudinal support, and a longitudinal displacement module motor for controlling the longitudinal movement of the lateral support on the longitudinal displacement module guide rail. This application provides an automated and intelligent weighing device based on Internet control. This device can achieve efficient and stable silicon-coating reaction, and can also achieve automated magnetic attraction and cleaning, which greatly improves production efficiency and product quality.

[0032] The embodiments of this application will now be described in detail with reference to the accompanying drawings. However, those skilled in the art will understand that many technical details have been provided in the embodiments of this application to facilitate a better understanding of the application. However, the technical solutions claimed in this application can be implemented even without these technical details and various variations and modifications based on the following embodiments.

[0033] refer to Figure 1 and Figure 2 This application provides a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device. The device includes: a base plate 1 and a magnetic attraction module 5 and an ultrasonic stirring module 6 mounted on the base plate 1; the magnetic attraction module 5 is connected to the base plate 1 via a lateral displacement module 3, which controls the lateral movement of the magnetic attraction module 5; the ultrasonic stirring module 6 is connected to the base plate 1 via a longitudinal displacement module 2, which controls the longitudinal movement of the ultrasonic stirring module 6; the lateral displacement module 3 includes a lateral displacement module support 301, a lateral displacement module guide rail 302, and a lateral displacement module motor 303 for controlling the lateral movement of the lateral displacement module support 301 on the lateral displacement module guide rail 302; see also... Figure 4 The longitudinal displacement module 2 includes a longitudinal displacement module transverse support 202 and a longitudinal displacement module longitudinal support 201. The longitudinal displacement module longitudinal support 201 is provided with a longitudinal displacement module guide rail 203. The longitudinal displacement module 2 also includes a longitudinal displacement module motor 204 for controlling the longitudinal movement of the longitudinal displacement module transverse support 202 on the longitudinal displacement module guide rail 203.

[0034] This application primarily addresses the challenge of integrating the in-situ silicon-coating synthesis of magnetic micro / nano materials such as magnetic beads with the magnetic attraction and cleaning processes in existing magnetic micro / nano material preparation methods, and enabling large-scale experimental deployment. The device provided in this application features multiple magnetic attraction and cleaning channels, and automates the magnetic attraction and cleaning processes. Simultaneously, the device incorporates ultrasonic and stirring functions through an ultrasonic stirring module 6. Furthermore, the device includes a multi-channel control displacement module, comprising a longitudinal multi-channel displacement module (longitudinal displacement module 2) and a transverse multi-channel displacement module (transverse displacement module 3). The longitudinal multi-channel displacement module controls the longitudinal movement of the ultrasonic, stirring, heating, liquid inlet / outlet, and reagent droplet modules. The transverse multi-channel displacement module controls the transverse movement of the multi-channel magnets.

[0035] Please continue reading. Figure 1In some embodiments, the longitudinal displacement module 2 includes two longitudinal displacement module supports 201 disposed at both ends of the base plate 1, and a transverse support 202 of the longitudinal displacement module is disposed at both ends of the two longitudinal displacement module supports 201; the ultrasonic stirring module 6 is fixedly connected to the transverse support 202 of the longitudinal displacement module; the longitudinal displacement module motor 204 is a lifting motor used to control the longitudinal movement of the transverse support 202 of the longitudinal displacement module, so as to drive the ultrasonic stirring module 6 to move longitudinally; the longitudinal direction is perpendicular to the base plate 1, that is, the height direction of the longitudinal displacement module supports 201.

[0036] Figure 2 This is a 3D view of the device from the rear side. See also... Figure 2 In some embodiments, the lateral displacement module includes two modules 3, which are respectively mounted on the longitudinal supports 201 of the longitudinal displacement module at both ends of the base plate 1. The lateral support 301 of the lateral displacement module is mounted between the longitudinal supports 201 of the longitudinal displacement module at both ends of the base plate 1, and the magnetic module 5 is mounted on the lateral support 301 of the lateral displacement module. The lateral displacement module motor 303 is a stepper motor, and the output shaft of the stepper motor is connected to a lead screw. The stepper motor controls the movement of the lead screw to control the lateral movement of the lateral support 301 of the lateral displacement module, thereby driving the magnetic module 5 to move laterally. The lateral direction is parallel to the base plate 1 and perpendicular to the lateral support 202 of the longitudinal displacement module, that is, the lateral direction is the length direction of the lateral support 301 of the lateral displacement module.

[0037] It should be noted that both the longitudinal displacement module motor 204 and the lateral displacement module motor 303 are electrically connected to the motor controller 10, and the motor controller 10 controls different motors to perform corresponding actions.

[0038] See Figure 1 and Figure 3 In some embodiments, the ultrasonic stirring module 6 includes multiple ultrasonic stirring units 601 arranged sequentially along the length of the transverse support 202 of the longitudinal displacement module. Each ultrasonic stirring unit 601 includes a support bracket 602 and an ultrasonic stirring paddle 603 penetrating the support bracket 602. The support bracket 602 is fixedly connected to the transverse support 202 of the longitudinal displacement module. The ultrasonic stirring paddle 603 is connected to the output shaft of the ultrasonic stirring motor 604, and the ultrasonic stirring motor 604 controls the movement of the ultrasonic stirring paddle 603 to achieve ultrasonic and stirring operations.

[0039] Please continue reading. Figure 1 In some embodiments, the aforementioned multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device further includes: a heating module 7 and an inlet / outlet liquid pipe module 8 disposed on the base plate 1; see also Figure 5 and Figure 6The heating module 7 includes a heating rod 701 disposed beside the ultrasonic stirring paddle 603, and the heating rod 701 is fixedly connected to the support bracket 602; the liquid inlet / outlet pipe module 8 includes a liquid inlet pipe 801, a liquid outlet pipe 802, and a liquid inlet / outlet pipe placement groove 803; the liquid inlet pipe 801 and the liquid outlet pipe 802 are respectively disposed on both sides of the ultrasonic stirring paddle 603, and both the liquid inlet pipe 801 and the liquid outlet pipe 802 pass through the support bracket 602 and are fixedly connected to the support bracket 602; the liquid inlet / outlet pipe placement groove 803 is disposed above the support bracket 602.

[0040] like Figure 6 As shown, the inlet pipe 801 and the outlet pipe 802 provide inlet and outlet channels respectively, and can be automatically controlled by the program to inject cleaning liquid, perform cleaning, and discharge waste liquid after cleaning.

[0041] In some embodiments, the above-described multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device further includes: a reagent addition module 9 disposed on the base plate 1; see below. Figure 5 The reagent addition module 9 is used to add chemical reagents to the solvent bottle during the chemical synthesis reaction. The reagent addition module 9 includes a reagent dropper that penetrates the support bracket 602 and a reagent addition control pump 901 that controls the reagent addition. The reagent addition control pump 901 is electrically connected to the control module, and the reagent addition operation of the reagent dropper of the reagent addition module 9 is realized by controlling the reagent addition control pump 901.

[0042] In some embodiments, the heating module 7, the inlet / outlet pipe module 8, and the reagent adding module 9 are all fixedly connected to the transverse support 202 of the longitudinal displacement module; the longitudinal displacement module 2 controls the longitudinal movement of the transverse support 202 of the longitudinal displacement module, thereby driving the heating module 7, the inlet / outlet pipe module 8, and the reagent adding module 9 to move longitudinally.

[0043] In some embodiments, the magnetic module 5 includes a plurality of annular magnets 501, and each annular magnet 501 corresponds one-to-one with an ultrasonic stirring unit 601 of the ultrasonic stirring module 6. The movement direction of the annular magnets 501 is automatically controlled by a program to control whether they are magnetically attracted.

[0044] In some embodiments, the annular magnet 501 is a permanent magnet with an annular angle of 180 degrees.

[0045] In some embodiments, the above-mentioned multi-channel, automated chemical synthesis, magnetic attraction and in-situ cleaning device further includes: a reagent bottle holder 4 disposed on the base plate 1, the reagent bottle holder 4 being placed below the ultrasonic stirring module 6, and the reagent bottle holder 4 having a plurality of reagent bottle grooves 401, the positions of the reagent bottle grooves 401 corresponding one-to-one with the ultrasonic stirring units 601 of the ultrasonic stirring module 6.

[0046] like Figure 7As shown, the base plate 1 is also equipped with a multi-position reagent bottle storage platform that matches the number of ultrasonic stirring units 601 of the ultrasonic stirring module 6. Each bottle position is in the shape of a groove and is used to place chemical reaction reagent bottles, so that the device can carry out multi-channel chemical synthesis experiments that include heating, ultrasonication, stirring and other functions operating simultaneously or partially.

[0047] In some embodiments, both the longitudinal displacement module motor 204 and the lateral displacement module motor 303 are electrically connected to the control module. The control module has built-in control software, which is used to edit the action flow to execute different chemical reaction execution flows.

[0048] The following is a detailed description of the multi-channel, automated chemical synthesis, magnetic adsorption, and in-situ cleaning apparatus provided in this application through a specific embodiment.

[0049] This application provides a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device, mainly comprising a base plate 1, a longitudinal displacement module 2, a transverse displacement module 3, a reagent bottle holder 4, a magnetic attraction module 5, an ultrasonic stirring module 6, a heating module 7, a liquid inlet / outlet module 8, a reagent addition module 9, and a motor controller 10. The base plate 1 primarily supports all components. The longitudinal displacement module 2 includes a longitudinal support 201 and a transverse support 202. The transverse support 202 primarily supports the liquid inlets of the ultrasonic stirring module 6, heating module 7, liquid inlet / outlet module 8, and reagent addition module 9, and serves as the support 602 for the ultrasonic stirring module 6. The reagent bottle holder 4 is mainly used to hold reagent bottles for chemical synthesis experiments. The magnetic attraction module 5 is mainly used to adsorb magnetic micro / nano materials onto the reagent bottle wall to fix the magnetic micro / nano materials during the cleaning process. The ultrasonic stirring paddle 603 is mainly used for ultrasonication and stirring during the chemical synthesis reaction and cleaning process. Heating module 7 is mainly used for heating during chemical synthesis reactions. Liquid inlet / outlet module 8 is mainly used for adding liquid and removing cleaning waste liquid after the magnetic micro / nano material reaction is completed. Reagent addition module 9 is mainly used for adding reagents during the reaction process. The support bracket 602 of ultrasonic stirring module 6 is mainly used to support components such as ultrasonic stirring, heating, and liquid inlet / outlet. Motor controller 10 is mainly used to control the longitudinal movement of longitudinal displacement module 2 and the lateral movement of lateral displacement module 3.

[0050] The apparatus of this application will be described in detail below through an application example of multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning.

[0051] During the chemical synthesis reaction, the reagent bottle containing the reaction solution is placed on the reagent bottle holder 4. After placement, the motor controller 10 controls the longitudinal displacement module 2 to move the transverse support 202 of the longitudinal displacement module downward, so that the support 602 of the ultrasonic stirring module 6 reaches the vicinity of the upper edge of the reagent bottle, and the ultrasonic stirring paddle 603 and other modules enter the reaction solution. The solution is then heated, sonicated, and stirred under specific temperature conditions. Auxiliary reagents are added dropwise during the reaction. After the reaction is complete, the sonication and heating modules are stopped, and the stirring mode is activated. The magnetic suction module 5 is moved closer to the reagent bottle by controlling the lateral displacement module 3. Under the action of the magnetic suction module, the magnetic micro / nanomaterial is adsorbed onto the bottle wall. Then, the inlet / outlet module 8 is activated to drain the solution, removing waste liquid through the outlet pipe 802. After draining, anhydrous ethanol solution is injected into the reagent bottle through the inlet pipe 801. The magnetic suction module is then moved away, releasing the magnetic micro / nanomaterial from the bottle wall. Stirring and cleaning are performed again for 5 minutes. The magnetic suction module is moved again to fix the magnetic micro / nanomaterial to the bottle wall, and draining is performed again. This cleaning process is repeated 5 times to meet the reagent cleaning requirements. After cleaning, stirring is stopped, the magnetic suction module is moved away, a certain volume of anhydrous ethanol solution is injected through the inlet pipe, and the longitudinal displacement module 2 is activated to raise the support bracket 602 of the ultrasonic stirring module 6, obtaining an ethanol solution of the reacted magnetic micro / nanomaterial.

[0052] Based on the above technical solutions, this application provides a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device. The device includes: a base plate 1 and a magnetic attraction module 5 and an ultrasonic stirring module 6 disposed on the base plate 1; the magnetic attraction module 5 is connected to the base plate 1 via a lateral displacement module, which controls the lateral movement of the magnetic attraction module 5; the ultrasonic stirring module 6 is connected to the base plate 1 via a longitudinal displacement module, which controls the longitudinal movement of the ultrasonic stirring module 6; the lateral displacement module includes a lateral displacement module support 30. 1. A transverse displacement module guide rail 302 and a transverse displacement module motor 303 for controlling the transverse support 301 of the transverse displacement module to move laterally on the transverse displacement module guide rail 302; the longitudinal displacement module includes a longitudinal displacement module transverse support 202 and a longitudinal displacement module longitudinal support 201, the longitudinal displacement module longitudinal support 201 is provided with a longitudinal displacement module guide rail 203, and the longitudinal displacement module also includes a longitudinal displacement module motor 204 for controlling the longitudinal displacement module transverse support 202 to move longitudinally on the longitudinal displacement module guide rail 203.

[0053] This application addresses numerous problems existing in the integration of existing silicon-coated magnetic micro / nano material preparation devices with advanced manufacturing platforms such as intelligent and automated experimental platforms. It proposes a multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device. By integrating the magnetic attraction module 5, ultrasonic stirring module 6, heating module 7, and cleaning module, intelligent and automated experimental preparation is achieved. This eliminates the need to separate synthesis and cleaning processes, and also eliminates the need for multiple transfers of cleaning reagent bottles after adsorbing the magnetic rod, reducing manual operations and significantly improving experimental efficiency. Furthermore, the experimental equipment presented in this application has been experimentally verified and demonstrates excellent operational results.

[0054] Those skilled in the art will understand that the above-described embodiments are specific examples of implementing this application, and in practical applications, various changes in form and detail may be made without departing from the spirit and scope of this application. Any person skilled in the art can make their own modifications and alterations without departing from the spirit and scope of this application; therefore, the scope of protection of this application should be determined by the scope defined in the claims.

Claims

1. A multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device for the automated chemical synthesis of magnetic micro / nano materials, characterized in that, include: The base plate and the magnetic suction module, ultrasonic stirring module, heating module, inlet / outlet pipe module and reagent bottle holder disposed on the base plate; the inlet / outlet pipe module includes an inlet pipe and an outlet pipe, which respectively provide an inlet channel and an outlet channel; The magnetic suction module is connected to the base plate via a lateral displacement module, which controls the lateral movement of the magnetic suction module. After the reaction is complete, the magnetic suction module is moved closer to the reagent bottle on the reagent bottle holder by controlling the lateral displacement module. Under the action of the magnetic suction module, the magnetic micro / nano material is adsorbed onto the reagent bottle wall. Waste liquid is discharged through the outlet pipe. After the discharge is complete, cleaning solution is injected into the reagent bottle through the inlet pipe. Then the magnetic suction module moves away, and the magnetic micro / nano material is released from the reagent bottle wall. After stirring and cleaning again, the magnetic suction module is moved again to fix the magnetic micro / nano material on the bottle wall, and the liquid is discharged again. After cleaning is complete, stirring is stopped, the magnetic suction module moves away, a certain volume of solution is injected through the inlet pipe, and the longitudinal displacement module is activated to raise the support bracket of the ultrasonic stirring module, thus obtaining a solution of the magnetic micro / nano material after the reaction is completed. The ultrasonic stirring module, the heating module, and the inlet / outlet pipe module are all connected to the base plate via a longitudinal displacement module, and the longitudinal displacement module is used to control the synchronous longitudinal movement of the ultrasonic stirring module, the heating module, and the inlet / outlet pipe module. The lateral displacement module includes a lateral displacement module support, a lateral displacement module guide rail, and a lateral displacement module motor for controlling the lateral displacement module support to move laterally on the lateral displacement module guide rail. The longitudinal displacement module includes a transverse support and a longitudinal support. The longitudinal support is provided with a longitudinal displacement module guide rail. The longitudinal displacement module also includes a longitudinal displacement module motor for controlling the longitudinal movement of the transverse support on the longitudinal displacement module guide rail.

2. The multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device according to claim 1, characterized in that, The longitudinal displacement module includes two longitudinal displacement module supports disposed at both ends of the base plate, and the transverse longitudinal displacement module supports are horizontally disposed at both ends of the two longitudinal displacement module supports. The ultrasonic stirring module is fixedly connected to the transverse support of the longitudinal displacement module; The longitudinal displacement module motor is a lifting motor, used to control the longitudinal movement of the transverse support of the longitudinal displacement module, so as to drive the ultrasonic stirring module to move longitudinally; the longitudinal direction is perpendicular to the base plate.

3. The multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device according to claim 1, characterized in that, The lateral displacement module includes two modules, which are respectively mounted on the longitudinal support of the longitudinal displacement module at both ends of the base plate. The transverse support of the transverse displacement module is disposed between the longitudinal supports of the longitudinal displacement module at both ends of the base plate, and the magnetic suction module is disposed on the transverse support of the transverse displacement module. The lateral displacement module motor is a driving stepper motor, and the output shaft of the driving stepper motor is connected to a lead screw. The driving stepper motor controls the lateral movement of the lateral displacement module's lateral support by controlling the movement of the lead screw, thereby driving the magnetic module to move laterally. The lateral movement is parallel to the base plate and perpendicular to the longitudinal displacement module's lateral support.

4. The multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device according to claim 1, characterized in that, The ultrasonic stirring module includes multiple ultrasonic stirring units arranged sequentially along the length of the transverse support of the longitudinal displacement module. Each ultrasonic stirring unit includes a support bracket and an ultrasonic stirring paddle that passes through the support bracket. The support bracket is fixedly connected to the transverse support of the longitudinal displacement module.

5. The multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device according to claim 4, characterized in that, The heating module includes a heating rod disposed next to the ultrasonic stirring paddle, and the heating rod is fixedly connected to the support bracket. The inlet and outlet pipe module also includes an inlet and outlet pipe placement groove; the inlet pipe and the outlet pipe are respectively arranged on both sides of the ultrasonic stirring paddle, and the inlet pipe and the outlet pipe both pass through the support bracket and are fixedly connected to the support bracket; the inlet and outlet pipe placement groove is arranged above the support bracket.

6. The multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device according to claim 5, characterized in that, Also includes: The reagent dispensing module is mounted on the base plate; The reagent addition module is used to add chemical reagents to the solvent bottle during the chemical synthesis reaction process. The reagent dispensing module includes a reagent dropper that runs through the support bracket and a reagent dispensing control pump that controls the dispensing of reagents.

7. The multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device according to claim 6, characterized in that, The heating module, the inlet / outlet liquid pipe module, and the reagent dispensing module are all fixedly connected to the transverse support of the longitudinal displacement module; the longitudinal displacement module controls the longitudinal movement of the transverse support of the longitudinal displacement module, thereby driving the heating module, the inlet / outlet liquid pipe module, and the reagent dispensing module to move longitudinally.

8. The multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device according to claim 1, characterized in that, The magnetic module includes multiple ring magnets, and each ring magnet corresponds to one of the ultrasonic stirring units of the ultrasonic stirring module; the ring magnets are permanent magnets with a ring angle of 180 degrees.

9. The multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device according to claim 1, characterized in that, The reagent bottle holder is placed below the ultrasonic stirring module, and the reagent bottle holder has multiple reagent bottle grooves, the positions of which correspond one-to-one with the ultrasonic stirring units of the ultrasonic stirring module.

10. The multi-channel, automated chemical synthesis, magnetic attraction, and in-situ cleaning device according to claim 1, characterized in that, Both the longitudinal displacement module motor and the lateral displacement module motor are electrically connected to the control module. The control module has built-in control software, which is used to edit the action flow to execute different chemical reaction execution flows.

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