A hydrogel patch preparation device and a preparation method thereof

CN118105906BActive Publication Date: 2026-10-09ZHEJIANG DINGTAI PHARMA
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Patent Information

Application Number
CN202410113114.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-01-26
Publication Date
2026-10-09
Estimated Expiration
2044-01-26

AI Technical Summary

Technical Problem

[0003]在生产水凝胶贴片时,需要先将水凝胶的水项和油项单独搅拌,然后将搅拌好的水项和油项混合在反应釜内搅拌混合,接着将搅拌好的水凝胶转移到涂布机上涂布切片,最后将切好的贴片凝固好即可;但是在传统的反应釜在搅拌水凝胶的过程中,水凝胶内会掺杂大量的气泡,从而导致生产出来的水凝胶贴片内含有气泡,使用效果则会大打折扣

Benefits of technology

[0019] 1. The present invention involves injecting a hydrogel mixture into a feeding mechanism, and then activating the feeding mechanism. The feeding mechanism injects the hydrogel mixture into the vacuum mixing chamber while maintaining a vacuum, and the mixing chamber stirs the hydrogel mixture in a relatively vacuum environment. As the hydrogel mixture is stirred, the air bubbles in the colloid are directly discharged, thereby effectively improving the quality of the hydrogel after stirring.

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Abstract

The application discloses a hydrogel patch preparation device and a preparation method thereof in the technical field of hydrogel production, which comprises a bottom plate, a fixing frame fixedly connected to the bottom plate, and a vacuum stirring box fixedly connected to the fixing frame; a supporting frame is fixedly connected to the bottom plate, a material withdrawing mechanism is arranged on the supporting frame, and the material withdrawing mechanism is used for taking out the stirred hydrogel from the vacuum stirring box under the condition that the vacuum stirring box is kept in vacuum; a first driving mechanism is arranged on the bottom plate, and the first driving mechanism is used for driving the operation of the material withdrawing mechanism; when feeding and discharging, the device can effectively prevent air from entering the vacuum stirring box, can avoid the operation of pumping out the air in the vacuum stirring box after completing one stirring, can effectively save the cost, and can improve the efficiency and effect of hydrogel stirring.
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Description

Technical Field

[0001] This invention relates to the field of hydrogel production technology, specifically to a hydrogel patch preparation device and its preparation method. Background Technology

[0002] Hydrogels are materials with a three-dimensional hydrophilic polymer network structure that contain pure water as a dispersion medium and are highly absorbent, capable of absorbing large amounts of water, thus exhibiting flexibility similar to natural tissues.

[0003] In the production of hydrogel patches, the water and oil components of the hydrogel need to be stirred separately first. Then, the stirred water and oil components are mixed in a reaction vessel and stirred together. Next, the stirred hydrogel is transferred to a coating machine for coating and cutting. Finally, the cut patches are solidified. However, in the traditional reaction vessel, a large number of air bubbles are mixed into the hydrogel during the stirring process, resulting in air bubbles in the produced hydrogel patches, which greatly reduces their effectiveness. Summary of the Invention

[0004] The purpose of this invention is to provide a hydrogel patch preparation device and method to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a hydrogel patch preparation apparatus and its preparation method, comprising a base plate, a fixing frame fixedly connected to the base plate, and a vacuum mixing chamber fixedly connected to the fixing frame; a feeding mechanism is provided on the upper side of the vacuum mixing chamber, the feeding mechanism being used to inject the hydrogel mixture to be mixed into the vacuum mixing chamber while keeping air out of the vacuum mixing chamber; a support frame is fixedly connected to the base plate, the support frame being provided with a material removal mechanism, the material removal mechanism being used to remove the mixed hydrogel from the vacuum mixing chamber while maintaining a vacuum; a first driving mechanism is provided on the base plate, the first driving mechanism being used to drive the operation of the material removal mechanism.

[0006] Preferably, the unloading mechanism includes a rotating frame located above a support frame. Unloading cylinders are symmetrically arranged on the front and rear sides of the support frame. A piston is installed inside each unloading cylinder, sealingly fitting against the inner wall of the cylinder, with a piston rod fixedly connected to the bottom end of the piston. The piston rod is slidably connected to the unloading cylinder. A first docking block is fixedly connected to the unloading cylinder, with first sealing plates symmetrically slidably connected to its left and right sides. A second docking block is fixedly connected to the bottom of the vacuum mixing tank, with second sealing plates symmetrically slidably connected to its left and right sides. A second driving mechanism is provided on the unloading cylinder to drive the first and second sealing plates to open. A first rotating mechanism is provided on the support frame to drive the rotating frame to rotate the two unloading cylinders relative to the support frame. A second rotating mechanism is provided on the support frame to drive the front unloading cylinder to rotate forward 90 degrees when the first rotating mechanism drives the two unloading cylinders to the front-rear position.

[0007] Preferably, the second driving mechanism includes an insert rod connected to a first sealing plate fixing rod; the second sealing plate has a slot, and the insert rod is clearance-fitted with the slot; a first push plate is provided at the bottom of the rotating cylinder and is slidably connected to a piston rod; the first push plate is in contact with the rotating cylinder and first slide rods are symmetrically slidably connected to the front and rear sides of the first push plate; connecting rods are symmetrically rotatably connected to the left and right sides of the first slide rods, and the other ends of the connecting rods on the left and right sides are respectively rotatably connected to the first sealing plates on the left and right sides; a first pushing mechanism is provided at the bottom of the first push plate, which is used to push the first docking block and the second docking block to seal and fit together, and after the first docking block and the second docking block are docked, push the two first slide rods to move upward.

[0008] Preferably, the first pushing mechanism includes a second push plate, which is located at the bottom of the first push plate and is slidably connected to the piston rod; a first spring is provided between the second push plate and the first push plate, with its upper and lower ends fixedly connected to the first push plate and the second push plate, respectively; a second spring is sleeved on the first slide rod, with its upper and lower ends fixedly connected to the first push plate and the first slide rod, respectively; the bottom part of the first slide rod is in contact with the second push plate; and the elastic force of the first spring is greater than the elastic force of the two second springs.

[0009] Preferably, the first rotating mechanism includes a first motor, which is fixedly connected to the support frame and the upper end of the output shaft of the first motor is fixedly connected to the rotating frame.

[0010] Preferably, the second rotating mechanism includes two rotating blocks, which are fixedly connected to piston rods on the front and rear sides respectively; each rotating block is rotatably connected to a rotating frame and a worm gear is fixedly connected to the rotating block, a worm is meshed on the worm gear, the worm is rotatably connected to the rotating frame and a gear is fixedly connected to the bottom end of the worm; a first rack and a second rack are fixedly connected to the left and right sides of the support frame respectively, the first rack and the second rack are both arc-shaped and have the same number of teeth, and the gears on the front and rear sides mesh with the first rack and the second rack respectively.

[0011] Preferably, the first driving mechanism includes a lifting frame, which is located inside the support frame and has cylinders fixedly connected to each of the four corners of the lifting frame. The bottom of each cylinder is fixedly connected to the base plate. The lifting frame is provided with a second pushing mechanism, which is used to push the second push plate on the rear side to move upward and to push the second push plate on the front side to move forward.

[0012] Preferably, the second pushing mechanism includes two threaded rods, which are distributed at the front and rear upper positions of the lifting frame. The threaded rods are rotatably connected to the lifting frame, and second slide rods are symmetrically arranged on the left and right sides of the threaded rods. The second slide rods are fixedly connected to the lifting frame. A push frame is threadedly connected to the threaded rod, and the push frame is slidably connected to the two second slide rods and is in contact with a second push plate. A second motor is fixedly connected to the rear position of the lifting frame. The upper end of the output shaft of the second motor is fixedly connected to the rear upper threaded rod, and the bottom end of the output shaft of the second motor is fixedly connected to a first bevel gear. A second bevel gear meshes with the first bevel gear, and both the first and second bevel gears are rotatably connected to the lifting frame. The second bevel gear is fixedly connected to the threaded rod at the front position.

[0013] Preferably, the feeding mechanism includes a feeding cylinder, which is fixedly connected to the vacuum mixing box and has two solenoid valves fixedly connected to it, with the two solenoid valves distributed on the upper and lower sides of the feeding cylinder.

[0014] A method for preparing a hydrogel patch, the specific steps of which are as follows:

[0015] Step 1: Inject the hydrogel mixture into the feeding mechanism. Start the feeding mechanism to inject the hydrogel mixture into the vacuum mixing chamber while ensuring the vacuum inside the vacuum mixing chamber.

[0016] Step 2: After mixing is complete, start the first drive mechanism, which will drive the unloading mechanism to run;

[0017] Step 3: The material removal mechanism removes the mixed hydrogel while maintaining a vacuum in the vacuum mixing chamber.

[0018] Compared with the prior art, the beneficial effects of the present invention are:

[0019] 1. The present invention involves injecting a hydrogel mixture into a feeding mechanism, and then activating the feeding mechanism. The feeding mechanism injects the hydrogel mixture into the vacuum mixing chamber while maintaining a vacuum, and the mixing chamber stirs the hydrogel mixture in a relatively vacuum environment. As the hydrogel mixture is stirred, the air bubbles in the colloid are directly discharged, thereby effectively improving the quality of the hydrogel after stirring.

[0020] 2. This invention, after the mixing in the vacuum mixing chamber is completed, activates the first drive mechanism, which in turn drives the unloading mechanism. The unloading mechanism can remove the mixed hydrogel while maintaining a relative vacuum in the vacuum mixing chamber. By using the loading and unloading mechanisms, air can be effectively prevented from entering the vacuum mixing chamber during loading and unloading. This avoids the need to remove air from the vacuum mixing chamber after each mixing cycle, effectively saving costs and improving the efficiency and effectiveness of hydrogel mixing. Attached Figure Description

[0021] Figure 1 This is a flowchart of the method of the present invention;

[0022] Figure 2 This is a schematic diagram of the overall structure of the present invention;

[0023] Figure 3 This is a schematic diagram of the rear view structure of the present invention;

[0024] Figure 4 This is a schematic diagram of the disassembled structure of the present invention;

[0025] Figure 5 This is a schematic diagram of the lifting frame in this invention;

[0026] Figure 6 This is a schematic diagram of the rotating frame in this invention;

[0027] Figure 7 This is a schematic diagram of the disassembled structure of the ejector cylinder in this invention;

[0028] Figure 8 This is a schematic diagram of the structure of the vacuum mixing tank in this invention.

[0029] The attached diagram lists the components represented by each number as follows:

[0030] 1. Base plate; 2. Fixing frame; 3. Vacuum mixing tank; 4. Support frame; 5. Rotating frame; 6. Unloading cylinder; 7. Piston; 8. Piston rod; 9. First docking block; 10. First sealing plate; 11. Second docking block; 12. Second sealing plate; 13. Insert rod; 14. Slot; 15. First push plate; 16. First slide rod; 17. Connecting rod; 19. Second push plate; 20. First spring; 21. Second spring; 22. First motor; 23. Rotating block; 24. Worm gear; 25. Worm; 26. Gear; 27. First rack; 28. Second rack; 29. ​​Lifting frame; 30. Cylinder; 31. Threaded rod; 32. Second slide rod; 33. Push frame; 34. Second motor; 35. First bevel gear; 36. Second bevel gear; 37. Loading cylinder; 38. Solenoid valve. Detailed Implementation

[0031] Preferred embodiments of the present invention will be described with reference to the accompanying drawings to provide a full understanding of the invention. Embodiments of the present invention can be varied in many forms, and the scope of the invention is not limited to the embodiments described in the following detailed description. These embodiments are provided to provide a more complete explanation of the invention to those skilled in the art. Therefore, to further emphasize the clear description, the shapes of elements in the drawings may be shown enlarged. In the various drawings, the same reference numerals are assigned to the same parts. Detailed descriptions of well-known functions and structures that are deemed likely to obscure the essence of the invention will be omitted.

[0032] Please see Figure 1-8 This invention provides a technical solution: a hydrogel patch preparation device and its preparation method, comprising a base plate 1, a fixing frame 2 fixedly connected to the base plate 1, and a vacuum mixing chamber 3 fixedly connected to the fixing frame 2; a feeding mechanism is provided on the upper side of the vacuum mixing chamber 3, which is used to inject the hydrogel mixture to be stirred into the vacuum mixing chamber 3 while keeping air out of the vacuum mixing chamber 3; a support frame 4 is fixedly connected to the base plate 1, and a material removal mechanism is provided on the support frame 4, which is used to remove the stirred hydrogel from the vacuum mixing chamber 3 while maintaining a vacuum; a first driving mechanism is provided on the base plate 1, which is used to drive the operation of the material removal mechanism;

[0033] like Figure 2-4As shown, when it is necessary to stir the hydrogel mixture, the hydrogel mixture is injected into the feeding mechanism, and then the feeding mechanism is started. The feeding mechanism will inject the hydrogel mixture into the vacuum mixing chamber 3 while maintaining a vacuum. When the hydrogel mixture is stirred in a relatively vacuum environment, the air bubbles in the colloid will be directly discharged, thereby effectively improving the quality of the stirred hydrogel. After the vacuum mixing chamber 3 has finished stirring, the first drive mechanism is started, which will drive the unloading mechanism to run. The unloading mechanism can remove the stirred hydrogel while maintaining a relatively vacuum in the vacuum mixing chamber 3. By using the feeding mechanism and the unloading mechanism during loading and unloading, air can be effectively prevented from entering the vacuum mixing chamber 3. This avoids the need to remove the air from the vacuum mixing chamber 3 after each stirring, effectively saving costs and improving the efficiency and effect of hydrogel stirring.

[0034] like Figure 6-8 As shown, as a further embodiment of the present invention, the unloading mechanism includes a rotating frame 5, which is located above the support frame 4. Unloading cylinders 6 are symmetrically arranged on the front and rear sides of the support frame 4. A piston 7 is provided inside the unloading cylinder 6, and the piston 7 is sealed to the inner wall of the unloading cylinder 6. A piston rod is fixedly connected to the bottom end of the piston 7, and the piston rod is slidably connected to the unloading cylinder 6. A first docking block 9 is fixedly connected to the unloading cylinder 6, and a first sealing plate 10 is symmetrically slidably connected to the left and right sides of the first docking block 9. A second docking block is fixedly connected to the bottom side of the vacuum mixing tank 3. 11. A second sealing plate 12 is symmetrically slidably connected to the left and right sides of the second docking block 11; a second driving mechanism is provided on the ejector cylinder 6, which is used to drive the first sealing plate 10 and the second sealing plate 12 to open; a first rotating mechanism is provided on the support frame 4, which is used to drive the rotating frame 5 to rotate the two ejector cylinders 6 relative to the support frame 4; a second rotating mechanism is provided on the support frame 4, which is used to drive the front ejector cylinder 6 to rotate forward 90 degrees when the first rotating mechanism drives the two ejector cylinders 6 to rotate to the front and rear positions;

[0035] After the hydrogel in the vacuum mixing chamber 3 is stirred, the first rotating mechanism is activated to drive the rotating frame 5 to rotate. The rotating frame 5 then drives an empty ejector cylinder 6 to rotate to the rear position. At this time, the ejector cylinder 6 is located directly below the vacuum mixing chamber 3. Then, the ejector cylinder 6 is driven to move upward. Since the piston 7 is initially located above the ejector cylinder 6 and cannot move upward, the space above the piston 7 in the ejector cylinder 6 is a relatively vacuum environment during the upward movement of the ejector cylinder 6. When the ejector cylinder 6 drives the first docking block 9 to move upward to the position where it docks with the second docking block 11, the second driving mechanism drives the first sealing plate 10 and the second sealing plate 12 to open, connecting the ejector cylinder 6 with the vacuum mixing chamber 3. The hydrogel in the vacuum mixing chamber 3 will then flow into the ejector cylinder 6. At the same time, the ejector cylinder 6 can also absorb the air generated during the stirring of the hydrogel in the vacuum mixing chamber 3. When the ejector cylinder 6 is filled with hydrogel, the second driving mechanism drives the first sealing plate 10 and the second sealing plate 12 to close, and then the ejector cylinder 6 is separated.

[0036] like Figure 7-8 As shown, as a further embodiment of the present invention, the second driving mechanism includes a rod 13, which is connected to the fixing rod of the first sealing plate 10; the second sealing plate 12 is provided with a slot 14, and the rod 13 is clearance-fitted with the slot 14; a first push plate 15 is provided at the bottom of the rotating cylinder and is slidably connected to the piston rod 7; the first push plate 15 is in contact with the rotating cylinder and first slide rods 16 are symmetrically slidably connected to the front and rear sides of the first push plate 15; connecting rods 17 are symmetrically rotatably connected to the left and right sides of the first slide rods 16, and the other ends of the connecting rods 17 on the left and right sides are respectively rotatably connected to the first sealing plates 10 on the left and right sides; a first pushing mechanism is provided at the bottom of the first push plate 15, which is used to push the first docking block 9 and the second docking block 11 to seal and fit together, and pushes the two first slide rods 16 to move upward after the first docking block 9 and the second docking block 11 are docked;

[0037] The first pushing mechanism includes a second push plate 19, which is located at the bottom of the first push plate 15 and is slidably connected to the piston rod 7. A first spring 20 is provided between the second push plate 19 and the first push plate 15, with its upper and lower ends fixedly connected to the first push plate 15 and the second push plate 19, respectively. A second spring 21 is sleeved on the first slide rod 16, with its upper and lower ends fixedly connected to the first push plate 15 and the first slide rod 16, respectively. The bottom part of the first slide rod 16 is in contact with the second push plate 19. The elastic force of the first spring 20 is greater than the elastic force of the two second springs 21.

[0038] When the second push plate 19 moves upward, it drives the first push plate 15 upward via the first spring 20. The first push plate 15 then drives the ejector cylinder 6 upward and the first slide rod 16 upward via the second spring 21. When the first mating block 9 on the ejector cylinder 6 is in contact with the second mating block 11, the insert rod 13 on the first sealing plate 10 is inserted into the slot 14 on the second sealing plate 12. At this time, the ejector cylinder 6 cannot move upward. When the second push plate 19 continues to move upward, it will start to compress the first spring 20 and push the two first slide rods 16 upward. When the first slide rods 16 move upward, they open... The first spring 21 is compressed and, through the two connecting rods 17 connected to it, drives the first sealing plates 10 on the left and right sides to move to the left and right sides respectively. When the first sealing plates 10 on the left and right sides move, they will drive the second sealing plates 12 on the left and right sides to move and open respectively. When the hydrogel in the vacuum mixing box 3 fills the discharge cylinder 6, it drives the second push plate 19 to move downward. At this time, the first spring 20 slowly returns to its original position. Under the action of the second spring 21, the first slide rod 16 moves downward against the second push plate 19. The second slide rod 32 will drive the first sealing plates 10 and the second sealing plates 12 on the left and right sides to close through the two connecting rods 17.

[0039] like Figure 6 As shown, as a further embodiment of the present invention, the first rotating mechanism includes a first motor 22, which is fixedly connected to the support frame 4 and the upper end of the output shaft of the first motor 22 is fixedly connected to the rotating frame 5.

[0040] The second rotating mechanism includes two rotating blocks 23, which are fixedly connected to the piston rods 7 on the front and rear sides respectively. The rotating blocks 23 are rotatably connected to the rotating frame 5 and a worm gear 24 is fixedly connected to the rotating blocks 23. A worm 25 meshes with the worm gear 24. The worm 25 is rotatably connected to the rotating frame 5 and a gear 26 is fixedly connected to the bottom end of the worm 25. A first rack 27 and a second rack 28 are fixedly connected to the left and right sides of the support frame 4 respectively. The first rack 27 and the second rack 28 are both arc-shaped and have the same number of teeth. The gears 26 on the front and rear sides mesh with the first rack 27 and the second rack 28 respectively.

[0041] When it is necessary to move the ejector cylinder 6 to the bottom position of the vacuum mixing tank 3, the first motor 22 is started, which drives the rotating frame 5 to rotate. The rotation of the rotating frame 5 drives the two ejector cylinders 6 to rotate, thus moving one of the ejector cylinders 6 to the bottom position of the vacuum mixing tank 3. At this point, the first motor 22 is stopped, and the hydrogel mixed in the vacuum mixing tank 3 is injected into the ejector cylinder 6. After the ejector cylinder 6 is full of mixed hydrogel, the first motor 22 is started again, driving the rotating frame 5 to rotate. The rotation of the rotating frame 5 drives the two gears 26 connected to it to rotate. When the gear 26 corresponding to the ejector cylinder 6 rotates to the position where it meshes with the second rack 28... At this time, as the rotating frame 5 rotates, the gear 26 begins to drive the worm 25 to rotate. When the worm 25 rotates, it drives the worm wheel 24 to rotate. The worm wheel 24 then drives the piston 7 rod to rotate through the rotating block 23. When the rotating frame 5 drives the ejector cylinder 6 to the foremost position, the piston 7 rod corresponding to the ejector cylinder 6 rotates exactly ninety degrees. At this time, the ejector cylinder 6 is in a folded-down state, which facilitates the discharge of hydrogel from the ejector cylinder 6. At the same time as the rotating frame 5 rotates, another gear 26 meshes with the first rack 27. Under the action of the first rack 27, when the other ejector cylinder 6 rotates to the rearmost position, the ejector cylinder 6 will remain in a vertical state.

[0042] like Figure 5 As shown, as a further embodiment of the present invention, the first driving mechanism includes a lifting frame 29, which is located inside the support frame 4 and has cylinders 30 fixedly connected to each of the four corners of the lifting frame 29. The bottom end of the cylinders 30 is fixedly connected to the base plate 1. A second pushing mechanism is provided on the lifting frame 29. The second pushing mechanism is used to push the second push plate 19 on the rear side to move upward and to push the second push plate 19 on the front side to move forward.

[0043] The second pushing mechanism includes two threaded rods 31, which are distributed in front of and above the rear of the lifting frame 29. The threaded rods 31 are rotatably connected to the lifting frame 29, and second slide rods 32 are symmetrically arranged on the left and right sides of the threaded rods 31. The second slide rods 32 are fixedly connected to the lifting frame 29. A pusher 33 is threadedly connected to the threaded rods 31. The pusher 33 is slidably connected to the two second slide rods 32 and is in contact with the second push plate 19. A second motor 34 is fixedly connected to the rear of the lifting frame 29. The upper end of the output shaft of the second motor 34 is fixedly connected to the threaded rod 31 above the rear, and the bottom end of the output shaft of the second motor 34 is fixedly connected to a first bevel gear 35. A second bevel gear 36 meshes with the first bevel gear 35, and both the first bevel gear 35 and the second bevel gear 36 are rotatably connected to the lifting frame 29. The second bevel gear 36 is fixedly connected to the threaded rod 31 at the front.

[0044] When the rotating frame 5 drives the two unloading cylinders 6 to the front and rear positions, the four cylinders 30 are activated to move the lifting frame 29 upward. As the lifting frame 29 moves upward, it drives the pushers 33 on both sides to move upward. The rear pusher 33 moves directly to a position where it contacts the bottom of the rear second push plate 19, and the front pusher 33 moves to a position where it contacts the rear of the front second push plate 19. At this point, the four cylinders 30 are stopped and the second motor 34 is activated. The second motor 34 drives the first bevel gear 35 and the rear screw... When the threaded rod 31 rotates, the first bevel gear 35 drives the second bevel gear 36 to rotate, and the second bevel gear 36 drives the front threaded rod 31 to rotate. When the threaded rods 31 on the front and rear sides rotate, they will drive the pushers 33 on the front and rear sides to move forward and upward respectively. When the second push plate 19 on the front side moves forward, it will open the two first sealing plates 10 on the front ejector cylinder 6. When the second push plate 19 on the rear side moves upward, it will drive the ejector cylinder 6 on the rear side to move upward and drive the first connecting block to dock with the second connecting block.

[0045] like Figure 8 As shown, as a further embodiment of the present invention, the feeding mechanism includes a feeding cylinder 37, which is fixedly connected to the vacuum mixing box 3 and has two solenoid valves 38 fixedly connected to it. The two solenoid valves 38 are distributed on the upper and lower sides of the feeding cylinder 37.

[0046] When it is necessary to inject the hydrogel mixture into the vacuum mixing tank 3, first open the solenoid valve 38 at the upper position inside the feeding cylinder 37. The hydrogel mixture will directly enter the feeding cylinder 37. When the hydrogel mixture fills the feeding cylinder 37, there is no air inside the feeding cylinder 37. Then close the solenoid valve 38 at the upper position and open the solenoid valve 38 at the lower position. At this time, the hydrogel mixture in the feeding tank will flow directly into the vacuum mixing tank 3.

[0047] like Figure 1 As shown, as a further aspect of the present invention, a method for preparing a hydrogel patch includes the following specific steps:

[0048] Step 1: Inject the hydrogel mixture into the feeding mechanism. Start the feeding mechanism to inject the hydrogel mixture into the vacuum mixing chamber 3 while ensuring a vacuum in the vacuum mixing chamber 3.

[0049] Step 2: After mixing is complete, start the first drive mechanism, which will drive the unloading mechanism to run;

[0050] Step 3: The material removal mechanism removes the mixed hydrogel while maintaining a vacuum in the vacuum mixing chamber 3.

[0051] The embodiments of the present invention described above are merely examples, and those skilled in the art can make various modifications or derive other equivalent embodiments. Therefore, the present invention is not limited to the embodiments mentioned in the above detailed description. Thus, the true scope of protection of the present invention should be determined according to the technical concept of the appended claims. Furthermore, it should be understood that the present invention includes all variations, equivalents, and alternatives to the concept of the present invention as defined by the appended claims.

Claims

1. A hydrogel patch preparation apparatus, comprising a base plate, characterized in that: A fixed frame is fixedly connected to the base plate, and a vacuum mixing chamber is fixedly connected to the fixed frame. A feeding mechanism is provided on the upper side of the vacuum mixing chamber, which is used to inject the hydrogel mixture to be mixed into the vacuum mixing chamber while keeping air out of the vacuum mixing chamber. A support frame is fixedly connected to the base plate, and a material ejection mechanism is provided on the support frame. The material ejection mechanism is used to remove the mixed hydrogel from the vacuum mixing chamber while maintaining a vacuum. A first drive mechanism is provided on the base plate, which is used to drive the operation of the material ejection mechanism. The unloading mechanism includes a rotating frame located above a support frame. Unloading cylinders are symmetrically arranged on the front and rear sides of the support frame. A piston is installed inside each unloading cylinder, sealingly fitting against the inner wall of the cylinder. A piston rod is fixedly connected to the bottom of the piston, and the piston rod is slidably connected to the unloading cylinder. A first docking block is fixedly connected to the unloading cylinder, and a first sealing plate is symmetrically slidably connected to the left and right sides of the first docking block. A second docking block is fixedly connected to the bottom of the vacuum mixing tank, and a second sealing plate is symmetrically slidably connected to the left and right sides of the second docking block. A second driving mechanism is provided on the unloading cylinder to drive the first and second sealing plates to open. A first rotating mechanism is provided on the support frame to drive the rotating frame to rotate the two unloading cylinders relative to the support frame. A second rotating mechanism is provided on the support frame to drive the front unloading cylinder to rotate forward 90 degrees when the first rotating mechanism drives the two unloading cylinders to the front and rear positions. The second driving mechanism includes an insert rod connected to a first sealing plate fixing rod; the second sealing plate has a slot, and the insert rod is clearance-fitted into the slot; a first push plate is provided at the bottom of the ejector cylinder and is slidably connected to a piston rod; the first push plate is in contact with the ejector cylinder and first sliding rods are symmetrically slidably connected to the front and rear sides of the first push plate; connecting rods are symmetrically rotatably connected to the left and right sides of the first sliding rods, and the other ends of the connecting rods on the left and right sides are respectively rotatably connected to the first sealing plates on the left and right sides; a first pushing mechanism is provided at the bottom of the first push plate, which is used to push the first docking block and the second docking block to seal and fit together, and push the two first sliding rods upward after the first docking block and the second docking block are docked; The first pushing mechanism includes a second push plate, which is located at the bottom of the first push plate and is slidably connected to the piston rod; a first spring is provided between the second push plate and the first push plate, with its upper and lower ends fixedly connected to the first push plate and the second push plate, respectively; a second spring is sleeved on the first slide rod, with its upper and lower ends fixedly connected to the first push plate and the first slide rod, respectively; the bottom part of the first slide rod is in contact with the second push plate; the elastic force of the first spring is greater than the elastic force of the two second springs.

2. The hydrogel patch preparation apparatus according to claim 1, characterized in that: The first rotating mechanism includes a first motor, which is fixedly connected to the support frame and the upper end of the output shaft of the first motor is fixedly connected to the rotating frame.

3. The hydrogel patch preparation apparatus according to claim 1, characterized in that: The second rotating mechanism includes two rotating blocks, which are fixedly connected to piston rods on the front and rear sides respectively. Each rotating block is rotatably connected to a rotating frame and a worm gear is fixedly connected to the rotating block. A worm is meshed on the worm gear, and the worm is rotatably connected to the rotating frame and a gear is fixedly connected to the bottom end of the worm. A first rack and a second rack are fixedly connected to the left and right sides of the support frame respectively. Both the first rack and the second rack are arc-shaped and have the same number of teeth. The gears on the front and rear sides mesh with the first rack and the second rack respectively.

4. The hydrogel patch preparation apparatus according to claim 1, characterized in that: The first driving mechanism includes a lifting frame, which is located inside the support frame and has cylinders fixedly connected to the four corners of the lifting frame. The bottom of the cylinders is fixedly connected to the base plate. The lifting frame is provided with a second pushing mechanism, which is used to push the second push plate on the rear side to move upward and push the second push plate on the front side to move forward.

5. The hydrogel patch preparation apparatus according to claim 4, characterized in that: The second pushing mechanism includes two threaded rods, which are distributed at the front and upper rear positions of the lifting frame. The threaded rods are rotatably connected to the lifting frame, and second sliding rods are symmetrically arranged on the left and right sides of the threaded rods. The second sliding rods are fixedly connected to the lifting frame. A push frame is threadedly connected to the threaded rod, and the push frame is slidably connected to the two second sliding rods and is in contact with a second push plate. A second motor is fixedly connected to the rear position of the lifting frame. The upper end of the output shaft of the second motor is fixedly connected to the upper rear threaded rod, and the bottom end of the output shaft of the second motor is fixedly connected to a first bevel gear. A second bevel gear meshes with the first bevel gear, and both the first and second bevel gears are rotatably connected to the lifting frame. The second bevel gear is fixedly connected to the threaded rod at the front position.

6. The hydrogel patch preparation apparatus according to claim 1, characterized in that: The feeding mechanism includes a feeding cylinder, which is fixedly connected to the vacuum mixing box and has two solenoid valves fixedly connected to it. The two solenoid valves are distributed on the upper and lower sides of the feeding cylinder.

7. A method for preparing a hydrogel patch, applicable to the hydrogel patch preparation apparatus according to any one of claims 1-6, characterized in that: The specific steps of this method are as follows: Step 1: Inject the hydrogel mixture into the feeding mechanism. Start the feeding mechanism to inject the hydrogel mixture into the vacuum mixing chamber while ensuring the vacuum inside the vacuum mixing chamber. Step 2: After mixing is complete, start the first drive mechanism, which will drive the unloading mechanism to run; Step 3: The material removal mechanism removes the mixed hydrogel while maintaining a vacuum in the vacuum mixing chamber.

Citation Information

Patent Citations

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