Capsule filling machine and method for the preparation of capsule granules

Abstract

The application relates to a capsule filling machine and a preparation method of capsule particles, which comprises a rack, a capsule stripping device, a filling device, a heating device, a capsule cover combining device and a controller. The rack comprises a capsule stripping station, a filling station, a heating station and a capsule cover combining station arranged in sequence. By arranging a first needle row group and a second needle row group in the filling device, the first shell is filled with medicine powder through the first needle row group, and the first shell is filled with medicine liquid through the second needle row group, so that the operations of filling the medicine powder and the medicine liquid can be simultaneously performed in one station, the production efficiency of the capsule particles is improved, and the process is reduced. In addition, the first needle row group and the second needle row group only need to be simultaneously driven by one driving mechanism, so that the purpose of reducing the equipment cost is achieved.

Description

Technical Field

[0001] This invention relates to the technical field of capsule filling, and more particularly to a capsule filling machine and a method for preparing capsule particles. Background Technology

[0002] In the manufacturing process of capsule drugs, it is generally necessary to go through a series of processing steps, including capsule peeling, powder filling, liquid filling, liquid drying, and capsule capping. These multiple processing steps are usually carried out by a capsule filling machine. The various processes are arranged in a circle with a turntable mechanism in the middle as a capsule filling turntable. As the capsule filling turntable rotates, each processing station will go through the above multiple processing steps in sequence, thereby completing the drug processing.

[0003] In the existing technology, the powder filling device and the liquid filling device are usually set up separately. The powder is filled by the powder filling device first, and then the liquid is filled by the liquid filling device. The capsule filling machine usually needs to be set up with five stations, which not only increases the process cost and reduces the production efficiency of capsule particles, but also increases the manufacturing cost of the capsule filling machine. Summary of the Invention

[0004] The first objective of this invention is to provide a capsule filling machine that addresses the technical problems of existing capsule filling machines having numerous processes, low capsule particle production efficiency, and high equipment costs.

[0005] To solve the above technical problems, a capsule filling machine is provided for preparing capsule shells into capsule granules. The capsule shell includes a first shell and a second shell, wherein the first shell is placed on a first material tray and the second shell is placed on a second material tray, comprising: The frame includes a capsule peeling station, a filling station, a heating station, and a capsule capping station arranged sequentially. A capsule stripping device is provided at the capsule stripping station; A filling device includes a moving component, a first driving component, a first needle array group, a second needle array group, a liquid supply component, and a powder supply component. The moving component, the first driving component, the liquid supply component, and the powder supply component are all mounted on the frame. The first needle array group and the second needle array group are both connected to the moving component. The first needle array group is connected to the powder supply component, and the second needle array group is connected to the liquid supply component. The moving component drives the first needle array group and the second needle array group to reciprocate along the X-axis and Z-axis directions. The first driving component drives the first material tray to rotate. A heating device is installed at the heating station; A capsule capping device is provided at the capsule capping station. The capsule capping device includes a second drive assembly, a pressing component, a third drive assembly, a collection container, and an air gun assembly. The second material tray is detachably connected to the second drive assembly, and the first material tray is installed on the third drive assembly. The second drive assembly and the collection container are respectively located on opposite sides of the third drive assembly. The second drive assembly is used to drive the pressing component and the second material tray closer to or away from the first material tray. The air gun assembly communicates with the first material tray and is located below the first material tray. The second drive assembly includes a telescopic component, a sliding component, and an elastic component. The pressing component is connected to the telescopic component. The telescopic component is provided with a sliding groove. The sliding component is slidably disposed in the sliding groove. The elastic component is disposed in the sliding groove and abuts against the telescopic component and the sliding component. The sliding component is used to connect to the second material tray. The third drive assembly is used to drive the first material tray to tilt. The controller is electrically connected to the capsule peeling device, the moving component, the first driving component, the drug supply liquid component, the drug powder component, the heating device, the second driving component, the third driving component, and the air gun component.

[0006] Further, the moving component includes a mounting component, a first drive motor, a second drive motor, a ball screw, a sliding rod, a sliding block, and an air chamber block. The mounting component is connected to the frame. The first drive motor and the sliding rod are mounted on the mounting component and connected to the ball screw. The sliding block is slidably mounted on the ball screw and the sliding rod. The second drive motor is connected between the sliding block and the air chamber block. The first needle array and the second needle array are respectively connected to the air chamber block. The liquid drug supply component and the powder drug supply component are respectively connected to the air chamber block. The first drive motor is used to drive the sliding block to reciprocate along the X-axis direction, and the second drive motor is used to drive the air chamber block to reciprocate along the Z-axis direction.

[0007] Furthermore, the first needle row group includes a plurality of first filling needles, the second needle row group includes a plurality of second filling needles, the plurality of first filling needles are arranged in a single row at intervals along a first straight line, the plurality of second filling needles are arranged in a single row at intervals along a second straight line, and the first straight line and the second straight line have a first preset angle.

[0008] Furthermore, the liquid drug supply assembly includes a liquid drug storage container, a first pipeline, and a first power pump; the powder drug supply assembly includes a powder drug storage container, a second pipeline, and a second power pump. The liquid drug storage container and the powder drug storage container are mounted on the frame. The liquid drug storage container and the air chamber block are connected through the first pipeline, and the powder drug storage container and the air chamber block are connected through the second pipeline.

[0009] Furthermore, the second drive assembly also includes a rotating component, which is mounted on the frame and connected to the telescopic component. The rotating component is used to drive the telescopic component to rotate within a second preset angle range.

[0010] Furthermore, the first material tray includes a plurality of spaced placement holes, a first vent hole, a second vent hole, and a third vent hole. The first vent hole, the second vent hole, and the third vent hole are all connected to the placement holes and the air gun assembly. The first material tray includes a first venting area, a second venting area, and a third venting area. The first vent hole is disposed in the first venting area, the second vent hole is disposed in the second venting area, and the third vent hole is disposed in the third venting area. In the direction from the second driving assembly toward the collection container, the first venting area, the second venting area, and the third venting area are arranged sequentially, and the apertures of the first vent hole, the second vent hole, and the third vent hole gradually decrease.

[0011] Furthermore, the third drive assembly includes a rotary motor and a clamping member, the rotary motor being connected between the frame and the clamping member; and / or, The air gun assembly includes an air pump, a third pipeline, and a venting component. The venting component is connected to the first material tray, and the air pump and the venting component are connected through the third pipeline.

[0012] Furthermore, the pressing element includes a pressing body and an extension post. The pressing body is connected to the second driving component, and the extension post is connected to the pressing body and disposed on a side close to the third driving component.

[0013] A second objective of this invention is to provide a method for preparing capsule granules using the aforementioned capsule filling machine, characterized by comprising the following steps: S1: Place the first material tray and the second material tray at the capsule peeling station, separate the capsule shells using the capsule peeling device, and place the first shell in the first material tray and the second shell in the second material tray; S2: The first material tray is placed on the first driving component, and the controller controls the moving component to drive the first needle array to extend into the placement hole and fill it with medicine powder; S3: The controller controls the first drive component to drive the first tray to rotate at a first preset angle; S4: The controller controls the moving component to drive the first needle array and the second needle array to extend into the placement hole while simultaneously filling the powder and liquid medicine and stirring. S5: Repeat step S4 until the first material tray rotates 360°, then control the first material tray to rotate the first preset angle. S6: The controller controls the moving component to drive the second needle array to extend into the placement hole and fill it with medicine; S7: Place the first tray inside the heating device and heat it for a preset time before removing it; S8: The first material tray is installed on the third drive assembly, and the second material tray is installed on the second drive assembly; S9: The controller controls the second drive component to drive the pressing member and move the second material tray close to the first material tray, so that the first shell and the second shell are combined into capsule particles; S10: The controller controls the second drive component to drive the pressing element and move the second material tray away from the first material tray; S11: The controller controls the third drive component to drive the first tray to rotate at a third preset angle; S12: The controller controls the air gun assembly to open, so that the capsule particles move into the collection container.

[0014] Furthermore, step S4 specifically includes: S41: The controller controls the moving component to drive the first needle row group and the second needle row group to move a first preset distance from a preset initial position along the Z-axis direction; S42: The controller controls the moving component to drive the first needle row group and the second needle row group to move a second preset distance along the X-axis direction; S43: The controller controls the moving component to drive the first needle row group and the second needle row group back to the preset initial position along the Z-axis direction.

[0015] Implementing the embodiments of the present invention will have the following beneficial effects: In one embodiment, by setting a first needle row group and a second needle row group in the filling device, the first needle row group fills the first shell with powder and the second needle row group fills the first shell with liquid medicine, the operation of filling powder and liquid medicine can be carried out simultaneously at one station. This not only reduces the number of processes and improves the production efficiency of capsule particles, but also only requires one drive mechanism to drive the first needle row group and the second needle row group simultaneously, thereby reducing equipment costs. In another embodiment, the capsule filling machine of this application is equipped with an air gun assembly. After the capsule particles are prepared, the first material tray is tilted by the third drive assembly, and then the capsule particles are blown out into the collection container by the air gun assembly. In addition, with the first air hole, second air hole and third air hole of different aperture sizes, the third air hole closer to the collection container has a small aperture and the first air hole farther away from the collection container has a large aperture. This structural design can control the airflow so that all the capsule particles can fall into the first material tray and no capsule particles will remain in the first material tray. In another embodiment, in the method of preparing capsule granules using a capsule filling machine, when filling a first material tray, only powder is filled the first time, and only liquid is filled the last time. Otherwise, both liquid and powder are filled simultaneously. That is, assuming that the first material tray needs to rotate N times to complete one revolution, the method of preparing capsule granules in this application only needs to rotate the first material tray N+1 times to fill all the first shells in the first material tray with liquid and powder. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a top view of the capsule filling machine according to an embodiment of the present invention; Figure 2 for Figure 1 A sectional view along line AA. Figure 3 This is a perspective view of the capsule filling machine according to an embodiment of the present invention; Figure 4 for Figure 3 A magnified view of a portion of point B in the middle; Figure 5 This is a front view of the capsule filling machine according to an embodiment of the present invention; Figure 6 This is a schematic diagram of the combination of the first needle row group and the second needle row group according to an embodiment of the present invention; Figure 7 This is a top view of the first material tray according to an embodiment of the present invention; Figure 8 This is a schematic diagram of the control system of the capsule filling machine according to an embodiment of the present invention; Figure 9 This is a flowchart illustrating the method for preparing capsule granules using a capsule filling machine according to an embodiment of the present invention; Figure 10 This is a flowchart illustrating step S4 as described in an embodiment of the present invention. Figure 11 This is a schematic diagram showing the first filling needle in a preset initial position according to an embodiment of the present invention; Figure 12 This is a schematic diagram showing the position of the first filling needle extending into the first shell according to an embodiment of the present invention.

[0018] Wherein: 100, capsule filling machine; 101, first linear assembly; 102, second linear assembly; 110, machine frame; 111, capsule peeling station; 112, filling station; 113, heating station; 114, capsule capping station; 120, capsule peeling device; 130, filling device; 131, moving assembly; 1311, mounting component; 1312, first drive motor; 1313, second drive motor; 1314, ball screw; 1315, sliding rod; 1316, sliding block; 1317, air chamber block; 132, first drive assembly; 133, first needle assembly; 1331, first filling needle; 134, second needle assembly; 1341, second filling needle; 135, drug supply assembly; 1351, drug storage container; 1352, first pipeline; 136. Powder supply assembly; 1361. Powder storage container; 1362. Second pipeline; 140. Heating device; 150. Capsule closing device; 151. Second drive assembly; 1511. Telescopic component; 1512. Sliding component; 1513. Elastic component; 1514. Rotating component; 152. Pressing component; 1521. Pressing body; 1522. Extension column; 153. Third drive assembly; 1531. Rotary motor; 1532. Clamping component; 154. Collection container; 155. Air gun assembly; 1551. Air pump; 1552. Third pipeline; 1553. Ventilation component; 160. Controller; 200, First material tray; 210, Placement hole; 220, First vent hole; 230, Second vent hole; 240, Third vent hole; 250, First ventilation zone; 260, Second ventilation zone; 270, Third ventilation zone; 300. Second tray. Detailed Implementation

[0019] To facilitate understanding of the present invention, a more complete description will be given below with reference to the accompanying drawings. Preferred embodiments of the invention are shown in the drawings. However, the invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to provide a thorough and complete understanding of the disclosure of the invention.

[0020] It should be noted that when a component is said to be "fixed to" another component, it can be directly attached to the other component or there may be an intervening component. When a component is said to be "connected to" another component, it can be directly connected to the other component or there may be an intervening component. The terms "vertical," "horizontal," "left," "right," and similar expressions used in this document are for illustrative purposes only.

[0021] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein in the specification of this invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0022] like Figure 1-12As shown, a capsule filling machine 100 is used to prepare capsule shells into capsule granules. The capsule shells include a first shell and a second shell. The first shell is placed on a first material tray 200, and the second shell is placed on a second material tray. The capsule filling machine 100 includes a frame 110, a capsule peeling device 120, a filling device 130, a heating device 140, a capsule capping device 150, and a controller 160. The frame 110 includes a capsule peeling station 111, a filling station 112, a heating station 113, and a capsule capping station 114 arranged sequentially. The capsule peeling device 120 is set at the capsule peeling station 111; the filling device 130 includes a moving component 131, a first driving component 132, a first needle row group 133, a second needle row group 134, a liquid supply component 135, and a powder supply component 136. The moving component 131, the first driving component 132, the liquid supply component 135, and the powder supply component 136 are all set on the frame 110. The first needle row group 133 and the second needle row group 134 are both connected to the moving component 131. The first needle row group 133 is connected to the powder supply component 136, and the second needle row group 134 is connected to the liquid supply component 135. The moving component 131 is used to drive the first needle row group 133 and the second needle row group 134 to reciprocate along the X-axis and Z-axis directions. The first driving component 132 is used to drive the first material tray 200 to rotate. A heating device 140 is installed at the heating station 113; a capsule capping device 150 is installed at the capsule capping station 114. The capsule capping device 150 includes a second drive assembly 151, a pressing element 152, a third drive assembly 153, a collection container 154, and an air gun assembly 155. A second material tray is detachably connected to the second drive assembly 151, and a first material tray 200 is installed on the third drive assembly 153. The second drive assembly 151 and the collection container 154 are respectively located on opposite sides of the third drive assembly 153. The second drive assembly 151 is used to drive the pressing element 152 and the second material tray to move closer to or away from the first material tray. The first material tray 200 and the air gun assembly 155 are connected to the first material tray 200 and are located below the first material tray 200. The second drive assembly 151 includes a telescopic member 1511, a sliding member 1512, and an elastic member 1513. The pressing member 152 is connected to the telescopic member 1511. The telescopic member 1511 is provided with a sliding groove. The sliding member 1512 is slidably disposed in the sliding groove. The elastic member 1513 is disposed in the sliding groove and abuts against the telescopic member 1511 and the sliding member 1512. The sliding member 1512 is used for connecting the second material tray. The third drive assembly 153 is used to drive the first material tray 200 to tilt. The controller 160 is electrically connected to the capsule peeling device 120, the moving assembly 131, the first drive assembly 132, the liquid medicine supply assembly 135, the powder medicine supply assembly 136, the heating device 140, the second drive assembly 151, the third drive assembly 153, and the air gun assembly 155.For example, the elastic element 1513 is a compression spring, used to move the second tray away from the first tray 200 and return it to its original position when the pressing element 152 does not apply pressure to the second tray. The capsule peeling device 120 adopts the prior art, which is common knowledge to those skilled in the art, so it is not described in detail here. Reference can also be made to Chinese Patent A Capsule Dispensing Device (Publication No. CN114053149A, Publication Date 2022.02.18); the heating device 140 adopts the prior art, which is common knowledge to those skilled in the art, so it is not described in detail here. Reference can also be made to Chinese Patent A Hard Capsule Drying Equipment (Publication No. CN219868884U, Publication Date 2023.10.20).

[0023] like Figure 1 , Figure 3 , Figure 5 As shown, in one embodiment, by setting a first needle row group 133 and a second needle row group 134 in the filling device 130, the first needle row group fills the first shell with powder, and the second needle row group 134 fills the first shell with liquid medicine. This enables the simultaneous filling of powder and liquid medicine at one station, which not only reduces the number of processes and improves the production efficiency of capsule particles, but also allows the first needle row group 133 and the second needle row group 134 to be driven by only one drive mechanism, thereby reducing equipment costs.

[0024] like Figure 1 , Figure 3 , Figure 5 As shown, in one possible implementation, the moving component 131 includes a mounting member 1311, a first drive motor 1312, a second drive motor 1313, a ball screw 1314, a sliding rod 1315, a sliding block 1316, and an air chamber block 1317. The mounting member 1311 is connected to the frame 110. The first drive motor 1312 and the sliding rod 1315 are mounted on the mounting member 1311 and connected to the ball screw 1314. The sliding block 1316 is slidably mounted on the ball screw 1314. 4. On the sliding rod 1315, the second drive motor 1313 is connected between the sliding block 1316 and the air chamber block 1317. The first needle row group 133 and the second needle row group 134 are respectively connected to the air chamber block 1317. The liquid medicine supply component 135 and the powder medicine supply component 136 are respectively connected to the air chamber block 1317. The first drive motor 1312 is used to drive the sliding block 1316 to reciprocate along the X-axis direction, and the second drive motor 1313 is used to drive the air chamber block 1317 to reciprocate along the Z-axis direction.

[0025] like Figure 1 , Figure 3 , Figure 6As shown, in one possible implementation, the first needle assembly 133 includes a plurality of first filling needles 1331, and the second needle assembly 134 includes a plurality of second filling needles 1341. The plurality of first filling needles 1331 are arranged in a single row with intervals along a first straight line 101, and the plurality of second filling needles 1341 are arranged in a single row with intervals along a second straight line 102. The first straight line 101 and the second straight line 102 have a first preset angle α. Exemplarily, in this embodiment, the first needle assembly 133 is provided with eight first filling needles 1331, and the second needle assembly 134 is provided with eight second filling needles 1341. That is, the capsule filling machine 100 of this application can fill eight capsule shells at one time, which is beneficial to improving the preparation efficiency of capsule particles. The first preset angle α is set to 10°, that is, the first material tray 200 needs to rotate 36 times for one revolution.

[0026] like Figure 1 , Figure 3 , Figure 5 As shown, in one possible implementation, the liquid medicine supply assembly 135 includes a liquid medicine storage container 1351, a first pipeline 1352, and a first power pump; the powder medicine supply assembly 136 includes a powder medicine storage container 1361, a second pipeline 1362, and a second power pump. The liquid medicine storage container 1351 and the powder medicine storage container 1361 are mounted on the frame 110. The liquid medicine storage container 1351 and the air chamber block 1317 are connected via the first pipeline 1352, and the powder medicine storage container 1361 and the air chamber block 1317 are connected via the second pipeline 1362. Exemplarily, the liquid medicine storage container 1351 is used to store liquid medicine, the main component of which is anhydrous ethanol; the powder medicine storage container 1361 is used to store powder medicine or granules. The first power pump is a water pump, and the second power pump is an air pump 1551, used to provide power to supply the liquid medicine and powder medicine.

[0027] like Figure 2 , Figure 3 , Figure 4 As shown, in one possible implementation, the second drive assembly 151 further includes a rotating member 1514, which is mounted on the frame 110 and connected to the telescopic member 1511. The rotating member 1514 drives the telescopic member 1511 to rotate within a second preset angle range. For example, the second preset angle is 180°. When the pressing member 152 applies pressure to the first and second shells to close them and form capsule particles, the rotating member 1514 drives the pressing member 152 to rotate 180°, ensuring that the pressing member 152 does not affect the subsequent removal of capsule particles.

[0028] like Figure 2 , Figure 4 , Figure 6As shown, in one possible implementation, the first tray 200 includes a plurality of spaced placement holes 210, a first vent hole 220, a second vent hole 230, and a third vent hole 240. The first vent hole 220, the second vent hole 230, and the third vent hole 240 are all connected to the placement hole 210 and the air gun assembly 155. The first tray 200 includes a first venting area 250, a second venting area 260, and a third venting area 270. The first vent hole 220 is located in the first venting area 250, the second venting hole 230 is located in the second venting area 260, and the third venting hole 240 is located in the third venting area 270. In the direction from the second drive assembly 151 toward the collection container 154, the first venting area 250, the second venting area 260, and the third venting area 270 are arranged sequentially, and the apertures of the first vent hole 220, the second venting hole 230, and the third venting hole 240 gradually decrease. For example, since the distance from the capsule particles to the collection container 154 is different at different locations, the force required to move the capsule to the collection container 154 is also different. It is understood that the aperture of the first vent 220 in the first venting zone 250, which is farther away from the collection container 154, is set to be larger, and the aperture of the third vent 240 in the third venting zone 270, which is closer to the collection container 154, is set to be smaller. The capsule filling machine 100 of this application is equipped with an air gun assembly 155. After the capsule particles are prepared, the first material tray 200 is tilted by the third drive assembly 153, and then the capsule particles are blown out into the collection container 154 by the air gun assembly 155. In addition, with the first air hole 220, the second air hole 230 and the third air hole 240 with different aperture sizes, the third air hole 240 closer to the collection container 154 has a smaller aperture, and the first air hole 220 farther away from the collection container 154 has a larger aperture. This structural design can control the airflow so that all the capsule particles can fall into the first material tray 200 and no capsule particles will remain in the first material tray 200.

[0029] like Figure 2 , Figure 4 , Figure 6 As shown, in one possible implementation, the third drive assembly 153 includes a rotary motor 1531 and a clamping member 1532, with the rotary motor 1531 connected between the frame 110 and the clamping member 1532. Exemplarily, the clamping member 1532 is used to secure the first tray 200 located at the capsule capping station 114.

[0030] like Figure 2 , Figure 4 , Figure 6 As shown, the air gun assembly 155 includes an air pump 1551, a third pipeline 1552, and an air vent 1553. The air vent 1553 is connected to the first material tray 200, and the air pump 1551 and the air vent 1553 are connected through the third pipeline 1552.

[0031] like Figure 2 , Figure 4 , Figure 6 As shown, in one possible implementation, the pressing member 152 includes a pressing body 1521 and an extension post 1522. The pressing body 1521 is connected to the second drive assembly 151, and the extension post 1522 is connected to the pressing body 1521 and disposed on a side close to the third drive assembly 153. Exemplarily, when the first shell and the second shell are closed, the telescopic member 1511 drives the pressing member 152 to move, thereby causing the extension post 1522 to apply pressure to the second shell, thus connecting the second shell to the first shell.

[0032] like Figure 8 , Figure 9 , Figure 10 As shown, a second objective of this invention is to provide a method for preparing capsule granules using the aforementioned capsule filling machine 100, characterized by comprising the following steps: S1: Place the first material tray 200 and the second material tray at the capsule peeling station 111, separate the capsule shells by the capsule peeling device 120, and place the first shell in the first material tray 200 and the second shell in the second material tray; S2: The first tray 200 is placed on the first drive assembly 132, and the controller 160 controls the moving assembly 131 to drive the first needle array 133 to extend into the placement hole 210 and fill it with powder; for example, the second needle array 134 is not working at this time.

[0033] S3: The controller 160 controls the first drive component 132 to drive the first tray 200 to rotate at a first preset angle α; for example, in this embodiment, the first preset angle α is 10°.

[0034] S4: Controller 160 controls the moving component 131 to drive the first needle row group 133 and the second needle row group 134 to extend into the placement hole 210, simultaneously filling the powder and liquid medicine and stirring. S5: Repeat step S4 until the first material tray 200 rotates 360°, then control the first material tray 200 to rotate the first preset included angle α; for example, step S4 needs to be repeated 35 times, that is, the first time is to fill the powder alone, the second to the 36th times are to fill the powder and liquid medicine at the same time, and the 37th time is to fill the liquid medicine alone.

[0035] S6: The controller 160 controls the moving component 131 to drive the second needle assembly 134 to extend into the placement hole 210 and fill it with liquid medicine; exemplarily, the first needle assembly 133 is not working at this time.

[0036] S7: Place the first tray 200 into the heating device 140 and heat for a preset time before removing it; S8: The first material tray 200 is installed on the third drive assembly 153, and the second material tray is installed on the second drive assembly 151; S9: Controller 160 controls the second drive assembly 151 to drive the pressing element 152 and move the second material tray close to the first material tray 200 so that the first shell and the second shell are combined into capsule particles. S10: Controller 160 controls the second drive assembly 151 to drive the pressing element 152 and move the second material tray away from the first material tray 200; S11: Controller 160 controls the third drive component 153 to drive the first material tray 200 to rotate at a third preset angle; exemplaryly, in this embodiment, the third preset angle is within the range of [24°, 40°]. When the first material tray 200 is tilted, the position near the collection container 154 is lower, and the position near the second drive component 151 is higher, which is more conducive to the capsule particles entering the collection container 154.

[0037] S12: Controller 160 controls the air gun assembly 155 to open, so that the capsule particles move into the collection container 154.

[0038] In another embodiment, the method of preparing capsule granules using the capsule filling machine 100 involves filling a first material tray 200. The first time, only powder is filled, and the last time, only liquid is filled. Otherwise, both liquid and powder are filled simultaneously. That is, assuming that the first material tray 200 needs to rotate N times to complete one revolution, the method of preparing capsule granules in this application only requires the first material tray 200 to rotate N+1 times to fill all the first shells in the first material tray 200 with liquid and powder.

[0039] like Figure 8 , Figure 9 , Figure 10 As shown, in one possible implementation, step S4 specifically includes: S41: Controller 160 controls the moving component 131 to drive the first needle array 133 and the second needle array 134 to move a first preset distance along the Z-axis from a preset initial position. For example, the first preset distance can be set by the user according to actual conditions. The purpose of setting the first preset distance is to control the position of the first needle array 133 and the second needle array 134 extending into the first housing. It is understood that the first needle array 133 and the second needle array 134 should not touch the bottom of the inner wall of the first housing. Specifically, assuming the inner cavity length of the first housing is L, and the bottom wall of the inner cavity is taken as the initial distance, the needle tip position of the first needle array 133 and the second needle array 134 when delivering powder or liquid medicine should be between [1 / 4L, 1 / 2L], which is beneficial for the liquid medicine and powder medicine to mix fully. Figure 12 This is a schematic diagram showing the position of the first filling needle 1331 extending into the first shell.

[0040] S42: Controller 160 controls moving component 131 to drive the first needle array 133 and the second needle array 134 to move a second preset distance along the X-axis direction; exemplary, the first needle array 133 and the second needle array 134 should not touch the inner cavity sidewall of the first shell. Specifically, assuming the inner cavity radius of the first shell is D, with the center of the inner cavity as the initial distance, the position of the needle tip of the second needle array 134 when delivering the medicine should be between [-3 / 4D, 3 / 4D], and the mixing of the medicine and powder is further enhanced by the stirring of the second needle array 134.

[0041] S43: Controller 160 controls the moving component 131 to drive the first needle row group 133 and the second needle row group 134 back to the preset initial position along the Z-axis. For example, the preset initial position is the position where the first needle row group 133 and the second needle row group 134 are not in operation, such as... Figure 11 As shown, it is located above the placement hole 210.

[0042] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the scope of protection of the present invention. Therefore, the scope of protection of this patent should be determined by the appended claims.

Claims

1. A capsule filling machine for preparing capsule shells into capsule granules, the capsule shell comprising a first shell and a second shell, the first shell being placed on a first material tray and the second shell being placed on a second material tray, characterized in that, include: The frame includes a capsule peeling station, a filling station, a heating station, and a capsule capping station arranged sequentially. A capsule stripping device is provided at the capsule stripping station; A filling device includes a moving component, a first driving component, a first needle array group, a second needle array group, a liquid supply component, and a powder supply component. The moving component, the first driving component, the liquid supply component, and the powder supply component are all mounted on the frame. The first needle array group and the second needle array group are both connected to the moving component. The first needle array group is connected to the powder supply component, and the second needle array group is connected to the liquid supply component. The moving component drives the first needle array group and the second needle array group to reciprocate along the X-axis and Z-axis directions. The first driving component drives the first material tray to rotate. A heating device is installed at the heating station; A capsule capping device is provided at the capsule capping station. The device includes a second drive assembly, a pressing component, a third drive assembly, a collection container, and an air gun assembly. A second material tray is detachably connected to the second drive assembly, and a first material tray is mounted on the third drive assembly. The second drive assembly and the collection container are respectively located on opposite sides of the third drive assembly. The second drive assembly drives the pressing component and the second material tray to move closer to or away from the first material tray. The first material tray includes multiple spaced placement holes, a first vent hole, a second vent hole, and a third vent hole. The air gun assembly communicates with the first vent hole, the second vent hole, the third vent hole, and the placement hole of the first material tray, and is located below the first material tray. The first material tray includes a first venting area, a second venting area, and a third venting area. The first vent is located in the first venting area, the second vent is located in the second venting area, and the third vent is located in the third venting area. In the direction from the second driving component toward the collection container, the first venting area, the second venting area, and the third venting area are arranged sequentially, and the diameters of the first vent, the second vent, and the third vent gradually decrease. The second driving component includes a telescopic member, a sliding member, and an elastic member. The pressing member is connected to the telescopic member. The telescopic member is provided with a sliding groove, and the sliding member is slidably disposed within the sliding groove. The elastic member is disposed within the sliding groove and abuts against the telescopic member and the sliding member. The sliding member is used to connect to the second material tray. The third driving component is used to drive the first material tray to tilt, and when tilted, the third vent is closer to the collection container than the first vent. The controller is electrically connected to the capsule peeling device, the moving component, the first driving component, the drug supply liquid component, the drug powder component, the heating device, the second driving component, the third driving component, and the air gun component.

2. The capsule filling machine according to claim 1, characterized in that, The moving component includes a mounting component, a first drive motor, a second drive motor, a ball screw, a sliding rod, a sliding block, and an air chamber block. The mounting component is connected to the frame. The first drive motor and the sliding rod are mounted on the mounting component and connected to the ball screw. The sliding block is slidably mounted on the ball screw and the sliding rod. The second drive motor is connected between the sliding block and the air chamber block. The first needle row assembly and the second needle row assembly are respectively connected to the air chamber block. The liquid drug supply assembly and the powder drug supply assembly are respectively connected to the air chamber block. The first drive motor is used to drive the sliding block to reciprocate along the X-axis direction, and the second drive motor is used to drive the air chamber block to reciprocate along the Z-axis direction.

3. The capsule filling machine according to claim 2, characterized in that, The first needle row group includes a plurality of first filling needles, and the second needle row group includes a plurality of second filling needles. The plurality of first filling needles are arranged in a single row with intervals along a first straight line, and the plurality of second filling needles are arranged in a single row with intervals along a second straight line, and the first straight line and the second straight line have a first preset angle.

4. The capsule filling machine according to claim 2, characterized in that, The liquid drug supply assembly includes a liquid drug storage container, a first pipeline, and a first power pump. The powder drug supply assembly includes a powder drug storage container, a second pipeline, and a second power pump. The liquid drug storage container and the powder drug storage container are mounted on the frame. The liquid drug storage container and the air chamber block are connected through the first pipeline, and the powder drug storage container and the air chamber block are connected through the second pipeline.

5. The capsule filling machine according to claim 1, characterized in that, The second drive assembly further includes a rotating component, which is mounted on the frame and connected to the telescopic component. The rotating component is used to drive the telescopic component to rotate within a second preset angle range.

6. The capsule filling machine according to claim 1, characterized in that, The third drive assembly includes a rotary motor and a clamping member, the rotary motor being connected between the frame and the clamping member; and / or, the air gun assembly includes an air pump, a third pipeline, and an air vent, the air vent being connected to the first material tray, and the air pump and the air vent being connected through the third pipeline.

7. The capsule filling machine according to claim 5, characterized in that, The pressing component includes a pressing body and an extension post. The pressing body is connected to the second driving component, and the extension post is connected to the pressing body and disposed on a side close to the third driving component.

8. A method for preparing capsule granules, using a capsule filling machine as described in any one of claims 1-7, characterized in that, Includes the following steps: S1: Place the first material tray and the second material tray at the capsule peeling station, separate the capsule shells using the capsule peeling device, and place the first shell in the first material tray and the second shell in the second material tray; S2: The first material tray is placed on the first driving component, and the controller controls the moving component to drive the first needle array to extend into the placement hole and fill it with medicine powder; S3: The controller controls the first drive component to drive the first tray to rotate at a first preset angle; S4: The controller controls the moving component to drive the first needle array and the second needle array to extend into the placement hole while simultaneously filling the powder and liquid medicine and stirring. S5: Repeat step S4 until the first material tray rotates 360°, then control the first material tray to rotate the first preset angle. S6: The controller controls the moving component to drive the second needle array to extend into the placement hole and fill it with medicine; S7: Place the first tray inside the heating device and heat it for a preset time before removing it; S8: The first material tray is installed on the third drive assembly, and the second material tray is installed on the second drive assembly; S9: The controller controls the second drive component to drive the pressing member and move the second material tray close to the first material tray, so that the first shell and the second shell are combined into capsule particles; S10: The controller controls the second drive component to drive the pressing element and move the second material tray away from the first material tray; S11: The controller controls the third drive component to drive the first tray to rotate at a third preset angle; S12: The controller controls the air gun assembly to open, so that the capsule particles move into the collection container.

9. The method for preparing capsule granules according to claim 8, characterized in that, Step S4 specifically includes: S41: The controller controls the moving component to drive the first needle row group and the second needle row group to move a first preset distance from a preset initial position along the Z-axis direction; S42: The controller controls the moving component to drive the first needle row group and the second needle row group to move a second preset distance along the X-axis direction; S43: The controller controls the moving component to drive the first needle row group and the second needle row group back to the preset initial position along the Z-axis direction.

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