一种基于高铁血红素的纳米酶及纳米酶库和其构建方法
By using methemoglobin, Fmoc-protected amino acids, and metal ions to self-assemble into nanozymes, the problems of harsh conditions and limited types in existing nanozyme preparation processes have been solved. Multiple nanozyme libraries have been constructed, which are suitable for drug screening and research, and have achieved low cost and wide application.
CN118179604BActive Publication Date: 2026-07-17ZHENGZHOU UNIV
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ZHENGZHOU UNIV
- Filing Date
- 2024-02-27
- Publication Date
- 2026-07-17
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Figure CN118179604B_ABST
Abstract
本发明公开了一种基于高铁血红素的纳米酶及纳米酶库和其构建方法，涉及纳米酶研究技术领域，本发明提供了一种新的纳米酶构建方法，以Hemin和Fmoc氨基酸之间的π‑π堆叠并以及加入不同的金属离子以促进配位的方式形成纳米酶的新种类，扩大了纳米酶的范围，根据氨基酸和金属离子的不同，还能构建由多种纳米酶组成的纳米酶库，便于多个领域药物的筛选和研究。
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