一种铁纳米酶及其制备方法和快速检测诺氟沙星中的应用
By preparing dumbbell-shaped iron nanozymes and combining them with enzyme inhibitors and chromogenic substrates, a rapid and low-cost quantitative detection of norfloxacin was achieved, solving the problems of high detection cost and poor stability in existing technologies, and providing a highly sensitive and selective method for the detection of norfloxacin.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- NANCHANG UNIV
- Filing Date
- 2024-03-21
- Publication Date
- 2026-07-17
AI Technical Summary
Existing norfloxacin detection methods are costly, have poor operational stability, are sensitive to reaction environments, are difficult to recover and reuse, and are time-consuming and complex, which limits their application in rapid detection.
Dumbbell-shaped iron nanozymes were prepared, and norfloxacin was visualized and detected using an ultraviolet spectrophotometer or RGB extraction detection method with enzyme inhibitors and chromogenic substrates. This simplified the pretreatment steps, reduced costs, and improved sensitivity and accuracy.
It enables rapid, simple, and low-cost quantitative detection of norfloxacin, with a detection range of 0.05-6.00 μmol/L and a detection limit of 27 nmol/L. It has good selectivity and anti-interference ability and is suitable for on-site visual detection.
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Figure CN118268037B_ABST