Molecular probe of dehydroascorbate reductase in higher plants and its application
CN118307437BActive Publication Date: 2026-08-28CHANGSHU INSTITUTE OF TECHNOLOGY
Patent Information
- Application Number
- CN202410421415.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-09
- Publication Date
- 2026-08-28
- Estimated Expiration
- 2044-04-09
AI Technical Summary
Technical Problem
[0003]目前市面上并没有专门针对脱氢抗坏血酸还原酶1的靶向抗体和分子探针，因此，对于该研究领域缺乏有效的抗体工具，用于不同植物类型、不同品系或不同发育时期该酶的细胞定位，活性以及表达水平的研究
Benefits of technology
[0020]本发明的一种高等植物脱氢抗坏血酸还原酶(DHAR)探针，对DHAR具有高亲和力和高特异性，能广泛地用于高等植物DHAR检测上，特别可用于检测植物体内脱氢抗坏血酸还原酶(DHAR)的活性，定位和含量；在蛋白质组学研究领域，本发明的探针提供了一个靶向蛋白研究的工具，使得对不同植物类型、不同品系或不同发育时期的蛋白表达变化及蛋白网络图谱的更深层次研究得以实现。
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Figure CN118307437B_ABST
Abstract
The present application belongs to the field of biotechnology, and relates to a high-selectivity probe for dehydroascorbate reductase in higher plants and application thereof. The present application provides a high-selectivity probe for dehydroascorbate reductase, which can specifically and covalently label proteins at cysteine residues. The present application can be used for detecting the activity, expression amount, and tissue and subcellular localization of dehydroascorbate reductase in higher plants. The probe of the present application provides a tool for targeted protein research, so that deeper research on protein expression changes and protein network maps of different plant types, different strains or different development periods can be realized.
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Citation Information
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